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15 results on '"Czakó Z"'

2. Synthesis and glycogen phosphorylase inhibitor activity of functionalized 1,4-benzodioxanes.

Author

Czakó Z, Docsa T, Gergely P, Juhász L, and Antus S

Subjects
Chromatography, Thin Layer, Hypoglycemic Agents chemical synthesis, Hypoglycemic Agents pharmacology, Indicators and Reagents, Magnetic Resonance Spectroscopy, Structure-Activity Relationship, Dioxanes chemical synthesis, Dioxanes pharmacology, Enzyme Inhibitors chemical synthesis, Enzyme Inhibitors pharmacology, Glycogen Phosphorylase antagonists & inhibitors
Abstract

A series of novel 1,4-benzodioxanes 11a-e and rac-12a-d carrying thiazolidine-2,4-dione moiety was synthesized and their glycogen phosphorylase inhibitor activity was also evaluated.

Published
2010

3. Synthesis and glycogen phosphorylase inhibitory activity of N-(beta-D-glucopyranosyl)amides possessing 1,4-benzodioxane moiety.

Author

Czakó Z, Juhász L, Kenéz A, Czifrák K, Somsák L, Docsa T, Gergely P, and Antus S

Subjects
Amides chemical synthesis, Animals, Dioxanes chemical synthesis, Molecular Structure, Rabbits, Structure-Activity Relationship, Amides chemistry, Amides pharmacology, Dioxanes chemistry, Dioxanes pharmacology, Glycogen Phosphorylase, Muscle Form antagonists & inhibitors, Glycogen Phosphorylase, Muscle Form metabolism
Abstract

A series of N-(beta-D-glucopyranosyl)amides 5d-i were synthesized by PMe(3) mediated Staudinger reaction of O-peracetylated beta-D-glucopyranosyl azide (1) followed by acylation with carboxylic acids 3d-i and subsequent Zemplén deacetylation. The new compounds were tested for their inhibitory activity against rabbit muscle glycogen phosphorylase and the structure-activity relationships of these compounds are also discussed in this paper.

Published
2009
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4. [Methicillin levels in the human serum, pericardial effusion and myocardium].

Author

Kiss J, Faragó E, Gömöry A, Czakó Z, Fäbiän E, and Bacsa S

Subjects
Adolescent, Adult, Bacterial Infections drug therapy, Child, Female, Heart Diseases surgery, Humans, Male, Methicillin blood, Methicillin therapeutic use, Preoperative Care, Methicillin metabolism, Myocardium metabolism, Pericardial Effusion metabolism
Abstract

The antibiotic level in the serum, pericardial fluid and myocardium of 11 patients prepared for heart surgery was tested by means of the agar-diffusion method after the intramuscular administration of 1 g of methicillin. The mean level after 1 to 3 hours was 14.7 mcg/ml in serum, 1.7 mcg/ml in the pericardial fluid and 8.2 mcg/g in the myocardium. In the case of drug sensitivity, the myocardial methicillin concentration is sufficient for the treatment of Gram-positive infections. If the infection is localized in the pericardium, higher doses, local applications, drug combination or complex therapy might be called for.

Published
1975

5. [Programmed pacemakers in clinical practice].

Author

Wórum F, Lörincz I, Gömöry A, Czakó Z, Kovács P, and Wórum I

Subjects
Adult, Aged, Aortic Valve Stenosis therapy, Coronary Disease therapy, Female, Heart Septal Defects, Atrial therapy, Humans, Male, Middle Aged, Myocardial Infarction therapy, Rheumatic Heart Disease therapy, Heart Diseases therapy, Pacemaker, Artificial instrumentation
Published
1979

6. [Problems of thoracic surgery in old age].

Author

Czakó Z, Schnitzler J, and Molnár E

Subjects
Age Factors, Bronchial Neoplasms surgery, Female, Humans, Lung Neoplasms surgery, Male, Postoperative Complications mortality, Aging, Thoracic Diseases surgery
Published
1974

7. [Cylindroma of the trachea].

Author

Czakó Z, Kollár S, and Jónás J

Subjects
Adult, Bronchoscopy, Carcinoma, Adenoid Cystic diagnostic imaging, Fascia Lata transplantation, Female, Humans, Radiography, Suture Techniques, Tracheal Neoplasms diagnostic imaging, Carcinoma, Adenoid Cystic surgery, Tracheal Neoplasms surgery
Published
1981

8. Effect of antibiotics on the results and complications or thoracic operations. Par II.

Author

Kiss J, Schnitzler J, Czakó Z, Juhász I, Molnár E, Móricz F, and Jékel P

Subjects
Anti-Bacterial Agents administration & dosage, Fever drug therapy, Humans, Respiratory Tract Diseases drug therapy, Surgical Wound Infection drug therapy, Wound Healing drug effects, Anti-Bacterial Agents therapeutic use, Postoperative Care, Postoperative Complications drug therapy, Thoracic Surgery adverse effects
Abstract

The role of antibiotics in the therapeutical result and in the postoperative complications was studied after 557 thoracic operations. It was found that antibiotics have no decisive role in the therapeutic result and there was no difference in the incidence of wound infections between the groups treated with different antibiotics. The principles and practice of treatment of would infections and pyothorax are discussed in detail. No relationship was found between the incidence of postoperative respiratory complications and the various drug treatments. Prevention and treatment of postoperative respiratory complications are discussed. The length of the febrile period was independent of the antibiotics applied. Their time of application, the problem of changing drugs and their side-effects after thoracic operations are analyzed.

Published
1978

9. The complications of mediastinoscopy.

Author

Bacsa S, Czakó Z, and Vezendi S

Subjects
Anesthesia adverse effects, Azygos Vein injuries, Bronchi, Child, Female, Foreign Bodies, Hemorrhage etiology, Humans, Lung Diseases diagnosis, Middle Aged, Pneumothorax etiology, Mediastinal Diseases diagnosis, Mediastinoscopy adverse effects
Published
1974

10. [Familial idiopathic fibrosing alveolitis].

Author

Barzó P, Szokol M, and Czakó Z

Subjects
Adult, Chronic Disease, Female, Humans, Pulmonary Alveoli pathology, Pulmonary Fibrosis pathology, Pulmonary Fibrosis genetics
Published
1981

11. [Early results of the resection of primary bronchiectasis].

Author

Czakó Z, Schnitzler J, Nagy M, and Kónya L

Subjects
Adolescent, Adult, Bronchial Fistula etiology, Child, Empyema etiology, Female, Humans, Male, Middle Aged, Pneumonectomy, Postoperative Complications, Bronchiectasis surgery
Published
1967

13. [Lieomyoma of the esophagus].

Author

Kiss J, Szentkereszty B, Czakó Z, and Nagy M

Subjects
Adult, Esophageal Neoplasms diagnostic imaging, Esophagogastric Junction surgery, Esophagoplasty, Female, Gastrectomy, Humans, Male, Middle Aged, Radiography, Esophageal Neoplasms surgery, Leiomyoma surgery
Published
1968

15. [Surgical results in primary bronchiectasis].

Author

Czakó Z, Schnitzler J, and Nagy M

Subjects
Adolescent, Adult, Anti-Bacterial Agents therapeutic use, Bronchiectasis drug therapy, Child, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prognosis, Bronchiectasis surgery
Published
1968

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