1. 3D Muscle Loss (3DML) assessment: A novel CT-based quantitative method to evaluate rotator cuff muscle fatty infiltration
- Author
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Werthel, Jean-David, Boux De Casson, François, Walch, Gilles, Gaudin, Pascal, Moroder, Philipp, Sanchez-Sotelo, Joaquin, CHAOUI, Jean, Burdin, Valérie, Hôpital Ambroise Paré [AP-HP], Département lmage et Traitement Information (IMT Atlantique - ITI), IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire de Traitement de l'Information Medicale (LaTIM), Institut National de la Santé et de la Recherche Médicale (INSERM)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-Université de Brest (UBO)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO), Département recherche et développement, Tornier SA, Tornier SA, Centre orthopédique Santy, 24, avenue Paul-Santy, 69008 Lyon, France, parent, Ramsay Générale de Santé - Hôpital Privé La Louvière, Clinique Jouvenet, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Mayo Clinic [Rochester], and IMASCAP Shoulder Augmented Surgery (Entreprise) (IMASCAP)
- Subjects
[SDV.IB]Life Sciences [q-bio]/Bioengineering - Abstract
International audience; IntroductionRotator cuff fatty infiltration (FI) is one of the most important parameters to predict the outcome of certain shoulder conditions. The primary objective of this study was to define a new computed tomography (CT)-based quantitative 3-dimensional (3D) measure of muscle loss (3DML) based on the rationale of the 2-dimensional (2D) qualitative Goutallier score. The secondary objective of this study was to compare this new measurement method to traditional 2D qualitative assessment of FI according to Goutallier et al and to a 3D quantitative measurement of fatty infiltration (3DFI).Materials and Methods102 CT scans from healthy shoulders (46) and shoulders with cuff tear arthropathy (21), irreparable rotator cuff tears (18), and primary osteoarthritis (17) were analyzed by three experienced shoulder surgeons for subjective grading of fatty infiltration according to Goutallier and their rotator cuff muscles were manually segmented. Quantitative 3D measurements of fatty infiltration (3DFI) were completed. The volume of muscle fibers without intra-muscular fat was then calculated for each rotator cuff muscle and normalized to the patient’s scapular volume to account for the effect of body size (NVfibers). Three-dimensional muscle mass (3DMM) was calculated by dividing the NVfibers value of a given muscle by the mean expected volume in healthy shoulders. Three-dimensional muscle loss (3DML) was defined as 1-(3DMM). The correlation between Goutallier grading, 3DFI, and 3DML was compared using a Spearman Rank correlation.ResultsInterobserver reliability for the traditional 2D Goutallier grading was moderate for the infraspinatus (ISP=0.42) and fair for the supraspinatus (SSP=0.38), subscapularis (SSC=0.27) and teres minor (TM=0.27). 2D Goutallier grading was found to be significantly and highly correlated with 3DFI (SSP=0.79, ISP=0.83, SSC=0.69, TM=0.45) and 3DML (SSP=0.87, ISP=0.85, SSC=0.69, TM=0.46) for all four rotator cuff muscles (p
- Published
- 2021