327 results on '"Džubák, Petr"'
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2. Improved syntheses of P2X7 ligands based on substituted benzyl amide of pyroglutamic acid motif labelled with iodine-123 or iodine-125
3. Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells – Synthesis, potency, and mitochondrial mechanism of action
4. Nucleoside-based anticancer drugs: Mechanism of action and drug resistance
5. Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone)
6. Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition
7. Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes
8. Triterpenoid pyrazines and pyridines – Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
9. Activity of 1-aryl-4-(naphthalimidoalkyl) piperazine derivatives against Leishmania major and Leishmania mexicana
10. Characterization of drug effects on cell cultures from phase-contrast microscopy images
11. Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides
12. Identification of Cellular Targets of Active Substances Using Microscopic Methods and Fluorescent Probes
13. Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties
14. Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters
15. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX
16. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors
17. Antimicrobial and cytotoxic activity of (thio)alkyl hexopyranosides, nonionic glycolipid mimetics
18. Novel 5-Substituted Oxindole Derivatives as Bruton’s Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation
19. Síntesis y actividad antiproliferativa de una mezcla de derivados de (⁺ ̸ ₋) 7-cloro-(4-tioalquilquinolina). Inducción de apoptosis y daño sobre el ADN/ARN
20. Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives
21. Synthesis and Biological Evaluation of Oxindole Sulfonamide Derivatives as Bruton's Tyrosine Kinase Inhibitors**
22. Synthesis and Biological Profiling of Benzofuro‐Fused 7‐Deazapurine Nucleosides
23. A unique case of AH-dominant type nodular pulmonary amyloidosis presenting as a spontaneous pneumothorax: a case report and review of the literature
24. Design, Synthesis, and Cytotoxicity of New Oxindole Sulfonamide Derivatives as Bruton's Tyrosine Kinase Inhibitors
25. Cardiac amyloidosis: from clinical suspicion to morphological diagnosis
26. Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin
27. Anti-cancer activities of cytokinin ribosides
28. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells
29. The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the “classical” cytokinin ribosides
30. Synthesis and Biological Evaluation of Oxindole Sulfonamide Derivatives as Bruton's Tyrosine Kinase Inhibitors.
31. Supplementary Materials and Methods. Supplementary Figure 1. from 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action
32. Data from 7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action
33. Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells
34. Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation
35. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides
36. Improved syntheses of P2X7 ligands based on substituted benzyl amide of pyroglutamic acid motif labelled with iodine-123 or iodine-125.
37. Proteome Mapping of Cervical Mucus and Its Potential as a Source of Biomarkers in Female Tract Disorders
38. Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells
39. Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton
40. Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer’s disease
41. Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C–H Dibenzothiophenation and Negishi Coupling
42. Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage
43. Mixture Effects of Tryptophan Intestinal Microbial Metabolites on Aryl Hydrocarbon Receptor Activity
44. Toll-Like Receptor 7/8 Ligand, S28463, Suppresses Ascaris suum-induced Allergic Asthma in Nonhuman Primates
45. Synthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2H)-one Derivatives
46. Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity
47. Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid
48. Antiviral Activity of Selected Lamiaceae Essential Oils and Their Monoterpenes Against SARS-Cov-2
49. Learning to segment cell nuclei in phase-contrast microscopy from fluorescence images for drug discovery
50. Synthesis of various 5-alkoxymethyluracil analogues and structure–cytotoxic activity relationship study
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