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1. CUORE Opens the Door to Tonne-scale Cryogenics Experiments

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alessandria, F., Alfonso, K., Andreotti, E., Avignone III, F. T., Azzolini, O., Balata, M., Bandac, I., Banks, T. I., Bari, G., Barucci, M., Beeman, J. W., Bellini, F., Benato, G., Beretta, M., Bersani, A., Biare, D., Biassoni, M., Bragazzi, F., Branca, A., Brofferio, C., Bryant, A., Buccheri, A., Bucci, C., Bulfon, C., Camacho, A., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Capodiferro, M., Cappelli, L., Cardani, L., Cariello, M., Carniti, P., Carrettoni, M., Casali, N., Cassina, L., Celi, E., Cereseto, R., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Conventi, D., Copello, S., Cosmelli, C., Cremonesi, O., Crescentini, C., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Datskov, V., Davis, C. J., Del Corso, F., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Dompè, V., Di Vacri, M. L., Di Paolo, L., Drobizhev, A., Ejzak, L., Faccini, R., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fu, S. H., Fujikawa, B. K., Gaigher, R., Ghislandi, S., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Goett, J., Gorla, P., Gotti, C., Guandalini, C., Guerzoni, M., Guetti, M., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E. V., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, R. G., Huang, H. Z., Iannone, M., Ioannucci, L., Johnston, J., Kadel, R., Keppel, G., Kogler, L., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, R., Ma, L., Ma, Y. G., Maiano, C., Maino, M., Marini, L., Martinez, M., Amaya, C. Martinez, Maruyama, R. H., Mayer, D., Mazza, R., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Olcese, M., Olivieri, E., Orio, F., Orlandi, D., Ouellet, J. L., Pagan, S., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pedrotta, R., Pelosi, A., Perego, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Reindl, F., Rimondi, F., Risegari, L., Rosenfeld, C., Rossi, C., Rusconi, C., Sakai, M., Sala, E., Salvioni, C., Sangiorgio, S., Santone, D., Schaeffer, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Smith, A. R., Speller, D., Stivanello, F., Surukuchi, P. T., Taffarello, L., Tatananni, L., Tenconi, M., Terranova, F., Tessaro, M., Tomei, C., Ventura, G., Vetter, K. J., Vignati, M., Wagaarachchi, S. L., Wallig, J., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zarra, C., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution - comparable to semiconductor detectors - and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined., Comment: 45 pages, 14 figures
Published: 2021
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2. CUORE opens the door to tonne-scale cryogenics experiments

Author: Adams, DQ, Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Avignone, FT, Azzolini, O, Balata, M, Bandac, I, Banks, TI, Bari, G, Barucci, M, Beeman, JW, Bellini, F, Benato, G, Beretta, M, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Celi, E, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Datskov, V, Davis, CJ, Del Corso, F, Dell’Oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Di Vacri, ML, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Gaigher, R, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Guetti, M, Gutierrez, TD, Haller, EE, Han, K, Hansen, EV, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, and Huang, RG
Subjects: Nuclear and Plasma Physics, Synchrotrons and Accelerators, Physical Sciences, Cryogenic temperatures, Neutrinoless double beta decay, Dilution refrigerator, Ton-scale detector, Low temperature calorimeter, Rare event searches, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Nuclear and plasma physics, Particle and high energy physics
Abstract: The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution – comparable to semiconductor detectors – and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined.
Published: 2022

3. CUORE opens the door to tonne-scale cryogenics experiments

Author: Adams, DQ, Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Avignone, FT, Azzolini, O, Balata, M, Bandac, I, Banks, TI, Bari, G, Barucci, M, Beeman, JW, Bellini, F, Benato, G, Beretta, M, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Celi, E, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Datskov, V, Davis, CJ, Corso, FD, Dell'Oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Di Vacri, ML, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, SH, Fujikawa, BK, Gaigher, R, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Guetti, M, Gutierrez, TD, Haller, EE, Han, K, Hansen, EV, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, and Huang, RG
Subjects: Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics
Abstract: The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution – comparable to semiconductor detectors – and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined.
Published: 2021

4. Improved Limit on Neutrinoless Double-Beta Decay in $^{130}$Te with CUORE

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Di Domizio, S., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Ligi, C., Ma, Y. G., Ma, L., Marini, L., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Schmidt, B., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Speller, D., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zanotti, L., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment
Abstract: We report new results from the search for neutrinoless double-beta decay in $^{130}$Te with the CUORE detector. This search benefits from a four-fold increase in exposure, lower trigger thresholds and analysis improvements relative to our previous results. We observe a background of $(1.38\pm0.07)\cdot10^{-2}$ counts$/($keV$\cdot$kg$\cdot$yr$)$ in the $0\nu\beta\beta$ decay region of interest and, with a total exposure of 372.5 kg$\cdot$yr, we attain a median exclusion sensitivity of $1.7\cdot10^{25}$ yr. We find no evidence for $0\nu\beta\beta$ decay and set a $90\%$ CI Bayesian lower limit of $3.2\cdot10^{25}$ yr on the $^{130}$Te half-life for this process. In the hypothesis that $0\nu\beta\beta$ decay is mediated by light Majorana neutrinos, this results in an upper limit on the effective Majorana mass of 75-350 meV, depending on the nuclear matrix elements used., Comment: 7 pages, 5 figures
Published: 2019
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5. Results of CUORE

Author: Dell'Oro, S., Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Di Domizio, S., Dompè, V., Drobizhev, A., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Ma, Y. G., Ma, L., Marini, L., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Schmidt, B., Scielzo, N. D., Singh, V., Sisti, M., Speller, D., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) at the Laboratori Nazionali del Gran Sasso, Italy, is the world's largest bolometric experiment. The detector consists of an array of 988 TeO2 crystals, for a total mass of 742 kg. CUORE is presently in data taking, searching for the neutrinoless double beta decay of 130 Te. CUORE is operational since the spring of 2017. The initial science run already allowed to provide the most stringent limit on the neutrinoless double beta decay half-life of 130Te, and to perform the most precise measurement of the two-neutrino double beta decay half-life. Up to date, we have more than doubled the collected exposure. In this talk, we presenteded the most recent results and discuss the present status of the CUORE experiment., Comment: contribution to the 2019 EW/QCD/Gravitation session of the 54th Rencontres de Moriond
Published: 2019

6. Status and results from the CUORE experiment

Author: Campani, A, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Di Domizio, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Ligi, C, G., Y, Ma, L, Marini, L, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Sharma, V, Singh, V, Sisti, M, Speller, D, Surukuchi, PT, Taffarello, L, and Terranova, F
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Neutrinoless double beta decay, two-neutrino double beta decay, background model, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Astronomical sciences, Nuclear and plasma physics, Particle and high energy physics
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is a tonne-scale cryogenic experiment located at the Laboratori Nazionali del Gran Sasso that exploits bolometric technique to search for neutrinoless double beta decay (0νββ) of 130Te. The detector consists of a segmented array of 988 natural TeO2 cubic crystals arranged in a cylindrical compact structure of 19 towers. The detector construction was completed in August 2016 and data taking started in Spring 2017. In this work, we present a brief description of the bolometric technique for rare events search and the CUORE detector, then we concentrate on the data analysis results. In this respect, we focus on the procedure for data processing and on the first 0νββ results we obtained from a total TeO2 exposure of 86.3kg yr. Next, we illustrate the main background sources and the CUORE background model, from which we obtain the most precise measurement of 130Te 2νββ half-life to date. Finally, we discuss the improvements achieved with 2018 and 2019 detector optimization campaigns and the current perspectives of our experiment.
Published: 2020

7. Perspectives of lowering CUORE thresholds with Optimum Trigger

Author: Dompe, V, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Domizio, SD, Drobizhev, A, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Singh, V, Sisti, M, Speller, D, Taffarello, L, and Terranova, F
Subjects: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences
Abstract: CUORE is a cryogenic experiment that focuses on the search of neutrinoless double beta decay in 130Te and it is located at the Gran Sasso National Laboratories. Its detector consists of 988 TeO2 crystals operating at a base temperature of ∼10 mK. It is the first ton-scale bolometric experiment ever realized for this purpose. Thanks to its large target mass and ultra-low background, the CUORE detector is also suitable for the search of other rare phenomena. In particular the low energy part of the spectra is interesting for the detection of WIMP-nuclei scattering reactions. One of the most important requirements to perform these studies is represented by the achievement of a stable energy threshold lower than 10 keV. Here, the CUORE capability to accomplish this purpose using a low energy software trigger will be presented and described.
Published: 2020

8. Lowering the Energy Threshold of the CUORE Experiment: Benefits in the Surface Alpha Events Reconstruction: Comparison Between Optimum Trigger and Derivative Trigger Performance in the Search for 0 νββ

Author: Campani, A, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Di Domizio, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Ligi, C, Ma, YG, Ma, L, Marini, L, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Sharma, V, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, and Tomei, C
Subjects: Neutrinoless double beta decay, Trigger algorithms, Digital signal processing, Bolometers for dark matter research, Mathematical Physics, Classical Physics, Condensed Matter Physics, General Physics
Abstract: CUORE is a tonne-scale cryogenic experiment located at the Laboratori Nazionali del Gran Sasso that exploits bolometric technique to search for neutrinoless double beta decay of 130Te. Thanks to its very low background and large mass, CUORE is also a powerful tool to study a broad class of phenomena, such as solar axions and WIMP scattering. The ability to conduct such sensitive searches crucially depends on the energy threshold, which has to be kept as low as possible. In this contribution, we show how the trigger algorithm affects the sensitivity to low-energy phenomena and the interpretation of the energy spectrum. In particular, we focus on the impact that the trigger algorithm has on the identification of the coincidence events among different crystals and, consequently, on the reconstruction of the background.
Published: 2020

9. The CUORE Detector and Results

Author: Nutini, I, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Domizio, SD, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Ligi, C, Ma, YG, Ma, L, Marini, L, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, and Vignati, M
Subjects: Neutrinos, nu beta beta, Macro-calorimeters, Cryogenics, CUORE, Mathematical Physics, Classical Physics, Condensed Matter Physics, General Physics
Abstract: The cryogenic underground observatory for rare events (CUORE) is a cryogenic experiment searching for neutrinoless double beta decay (0 νββ) of 130Te. The detector consists of an array of 988TeO2 crystals arranged in a compact cylindrical structure of 19 towers. We report the CUORE initial operations and optimization campaigns. We then present the CUORE results on 0 νββ and 2 νββ decay of 130Te obtained from the analysis of the physics data acquired in 2017.
Published: 2020

10. CUORE: The first bolometric experiment at the ton scale for the search for neutrino-less double beta decay

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Ma, YG, Marini, L, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, and Tomei, C
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Neutrinoless double beta decay, Ton-scale detector, Bolometers, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences, Nuclear & Particles Physics, Nuclear and plasma physics
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the most massive bolometric experiment searching for neutrino-less double beta (0νββ) decay. The detector consists of an array of 988 TeO2 crystals (742 kg) arranged in a compact cylindrical structure of 19 towers. This paper will describe the CUORE experiment, including the cryostat, and present the detector performance during the first year of running. Additional detail will describe the effort made in improving the energy resolution in the 130Te 0νββ decay region of interest (ROI) and the suppression of backgrounds. A description of work to lower the energy threshold in order to give CUORE the sensitivity to search for other rare events, such as dark matter, will also be provided.
Published: 2020

11. Improved Limit on Neutrinoless Double-Beta Decay in Te130 with CUORE

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Di Domizio, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Ligi, C, G., Y, Ma, L, Marini, L, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Sharma, V, Singh, V, Sisti, M, Speller, D, Surukuchi, PT, Taffarello, L, and Terranova, F
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, CUORE Collaboration, nucl-ex, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract: We report new results from the search for neutrinoless double-beta decay in ^{130} Te with the CUORE detector. This search benefits from a fourfold increase in exposure, lower trigger thresholds, and analysis improvements relative to our previous results. We observe a background of (1.38±0.07)×10^{-2} counts/(keV kg yr)) in the 0νββ decay region of interest and, with a total exposure of 372.5 kg yr, we attain a median exclusion sensitivity of 1.7×10^{25} yr. We find no evidence for 0νββ decay and set a 90% credibility interval Bayesian lower limit of 3.2×10^{25} yr on the ^{130} Te half-life for this process. In the hypothesis that 0νββ decay is mediated by light Majorana neutrinos, this results in an upper limit on the effective Majorana mass of 75-350 meV, depending on the nuclear matrix elements used.
Published: 2020

12. Improved Limit on Neutrinoless Double-Beta Decay in ^{130} Te with CUORE.

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Di Domizio, S, Dompè, V, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Ligi, C, Ma, YG, Ma, L, Marini, L, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Sharma, V, Singh, V, Sisti, M, Speller, D, Surukuchi, PT, Taffarello, L, and Terranova, F
Subjects: CUORE Collaboration, nucl-ex, General Physics, Mathematical Sciences, Physical Sciences, Engineering
Abstract: We report new results from the search for neutrinoless double-beta decay in ^{130} Te with the CUORE detector. This search benefits from a fourfold increase in exposure, lower trigger thresholds, and analysis improvements relative to our previous results. We observe a background of (1.38±0.07)×10^{-2} counts/(keV kg yr)) in the 0νββ decay region of interest and, with a total exposure of 372.5 kg yr, we attain a median exclusion sensitivity of 1.7×10^{25} yr. We find no evidence for 0νββ decay and set a 90% credibility interval Bayesian lower limit of 3.2×10^{25} yr on the ^{130} Te half-life for this process. In the hypothesis that 0νββ decay is mediated by light Majorana neutrinos, this results in an upper limit on the effective Majorana mass of 75-350 meV, depending on the nuclear matrix elements used.
Published: 2020

13. Initial performance of the CUORE detector

Author: Cushman, JS, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, SD, Vacri, MLD, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V
Subjects: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract: CUORE, the Cryogenic Underground Observatory for Rare Events, is an experiment searching for the neutrinoless double-beta decay of 130Te. The first CUORE dataset was acquired in May and June 2017 and consisted of 10.6 kg-yr of TeO2 exposure, with several days of calibration data before and after the physics dataset. We discuss here the initial performance of the CUORE detector and cryostat in this first dataset.
Published: 2020

14. First results from the CUORE experiment

Author: Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, SD, Vacri, MLD, Dompe, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND
Subjects: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract: CUORE (Cryogenic Underground Observatory for Rare Events) is a ton-scale experiment aiming to the search of neutrino-less double beta decay in 130Te with a projected sensitivity on the Majorana effective mass close to the inverted hierarchy region. The CUORE detector consists of a segmented array of 988 TeO2 bolometers, organized in 19 towers and operated at a temperature of about 10 mK thanks to a custom cryogenic system which, besides the uncommon scale, observes several constraints from the radio-purity of the materials to the mechanical decoupling of the cooling systems. The successful commissioning of the CUORE cryogenic system has been completed early in 2016 and represents an outstanding achievement by itself. The installation of the detector proceeded along 2016 followed by the cooldown to base temperature at the beginning of 2017. The CUORE detector is now operational and has been taking science data since Spring 2017. With the first ∼3 weeks of collected data, we present here the most stringent constraint on the 130Te half-live for the neutrino-less double beta decay.
Published: 2020

15. Results of cuore

Author: Dell'Oro, S, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Ma, L, Marini, L, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, ND, Singh, V, Sisti, M, Speller, D, Taffarello, L, and Terranova, F
Subjects: nucl-ex
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) at the Laboratori Nazionali del Gran Sasso, Italy, is the world's largest bolometric experiment. The detector consists of an array of 988 TeO2 crystals, for a total mass of 742 kg. CUORE is presently in data taking, searching for the neutrinoless double beta decay of 130Te. CUORE is operational since the spring of 2017. The initial science run already allowed to provide the most stringent limit on the neutrinoless double beta decay half-life of 130Te, and to perform the most precise measurement of the two-neutrino double beta decay half-life. Up to date, we have more than doubled the collected exposure. In this talk, we presenteded the most recent results and discuss the present status of the CUORE experiment.
Published: 2020

16. Update on the recent progress of the CUORE experiment

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Dompè, V., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Ma, Y. G., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Reindl, F., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Scielzo, N. D., Singh, V., Sisti, M., Speller, D., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: CUORE is a 741 kg array of 988 TeO$_2$ bolometeric crystals designed to search for the neutrinoless double beta decay of $^{130}$Te and other rare processes. CUORE has been taking data since summer 2017, and as of summer 2018 collected a total of 86.3 kg$\cdot$yr of TeO$_2$ exposure. Based on this exposure, we were able to set a limit on the $0\nu\beta\beta$ half-life of $^{130}$Te of $T^{0\nu}_{1/2}>1.5\times10^{25}$ yr at 90% C.L. At this conference, we showed the decomposition of the CUORE background and were able to extract a $^{130}$Te $2\nu\beta\beta$ half-life of $T_{1/2}^{2\nu}=[7.9\pm0.1 \mathrm{(stat.)}\pm0.2 \mathrm{(syst.)}]\times10^{20}$ yr. This is the most precise measurement of this half-life and is consistent with previous measurements., Comment: Proceedings of the Neutrino 2018 Conference. 8 pages, 7 figures
Published: 2018

17. The CUORE cryostat

Author: D'Addabbo, A., Biassoni, M., Bucci, C., Caminata, A., Alduino, C., Bersani, A., Canonica, L., Cappelli, L., Ceruti, G., Chott, N., Copello, S., Cremonesi, O., Cushman, J. S., D'Aguanno, D., Davis, C. J., Dell'Oro, S., Di Domizio, S., Drobizhev, A., Faverzani, M., Ferri, E., Franceschi, M. A., Gladstone, L., Gorla, P., Ligi, C., Marini, L., Napolitano, T., Nucciotti, A., Nutini, I., Ouellet, J. L., Pagliarone, C. E., Pattavina, L., Rusconi, C., Santone, D., Schmidt, B., Singh, V., Speller, D., Taffarello, L., Terranova, F., Wallig, J., Welliver, B., and Wise, T.
Subjects: Physics - Instrumentation and Detectors
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is a bolometric experiment for neutrinoless double-beta decay in $^{130}$Te search, currently taking data at the underground facility of Laboratori Nazionali del Gran Sasso (LNGS). The CUORE cryostat successfully cooled down a mass of about 1 ton at $\sim$7\,mK, delivering an uniform and constant base temperature. This result marks a fundamental milestone in low temperature detectors techniques, opening the path for future ton-scale bolometric experiments searching for rare events. In this paper we present the CUORE cryogenic infrastructure, briefly describing its critical subsystems., Comment: 7 pages, 3 pictures, accepted by JLTP
Published: 2018
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18. Study of Rare Nuclear Processes with CUORE

Author: CUORE Collaboration, Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Dompè, V., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Reindl, F., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment, Physics - Instrumentation and Detectors
Abstract: TeO2 bolometers have been used for many years to search for neutrinoless double beta decay in 130-Te. CUORE, a tonne-scale TeO2 detector array, recently published the most sensitive limit on the half-life, $T_{1/2}^{0\nu} > 1.5 \times 10^{25}\,$yr, which corresponds to an upper bound of $140-400$~meV on the effective Majorana mass of the neutrino. While it makes CUORE a world-leading experiment looking for neutrinoless double beta decay, it is not the only study that CUORE will contribute to in the field of nuclear and particle physics. As already done over the years with many small-scale experiments, CUORE will investigate both rare decays (such as the two-neutrino double beta decay of 130-Te and the hypothesized electron capture in 123-Te), and rare processes (e.g., dark matter and axion interactions). This paper describes some of the achievements of past experiments that used TeO2 bolometers, and perspectives for CUORE., Comment: 36 pages, 13 figures, sumbitted to IJMPA Special Issue "Results and Developments in the investigation of rare nuclear decays and processes"
Published: 2018

19. CUORE: The first bolometric experiment at the ton scale for rare decay searches

Author: Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, SD, Vacri, MLD, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, and Santone, D
Subjects: Cryogenic, Superconductive Devices, Nuclear & Particles Physics, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Other Physical Sciences
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in August 2016 and data taking started in spring 2017. In this contribution the achievement of the commissioning phase and the performance of the detector and the cryostat during the first physics run will be presented.
Published: 2019

20. Results from the CUORE experiment

Author: Chiesa, D, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, and Schmidt, B
Subjects: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta (0νββ) decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in 2016 and data taking started in 2017. In this conference we present the 0νββ decay results of CUORE from examining a total TeO2 exposure of 86.3 kg yr, characterized by an effective energy resolution of 7.7 keV FWHM and a background in the region of interest of 0.014 counts/(keV kg yr). Based on these data, CUORE places a lower limit on the 0νββ decay half-life of (90% C.L.). We then discuss the latest updates in the analysis of background and in the evaluation of the half-life of 2νββ decay of 130Te.
Published: 2019

21. Results from the CUORE experiment

Author: Moggi, N, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fu, Z, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gruszko, J, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, and Schmidt, B
Subjects: Astronomy & Astrophysics
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. In this talk we present the neutrinoless doube beta decay results of CUORE from examining a total TeO2 exposure of 86.3 kg yr, characterized by an effective energy resolution of 7.7 keV FWHM and a background in the region of interest of 0.014 counts/(keV kg yr). In this physics run, CUORE placed a lower limit on the decay half-life of 130Te > 1.3×1025 yr (90% C.L.). We then discuss the additional improvements in the detector performance achieved in 2018 and the latest update on the evaluation of the background budget.
Published: 2019

22. Results from the CUORE experiment

Author: Campani, A, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomansi, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, and Scielzo, ND
Subjects: Astronomy & Astrophysics
Abstract: Neutrinoless double beta decay (0νββ) is a rare, second-order nuclear transition that occurs only if neutrinos are massive Majorana particles or through new physics beyond Standard Model. This process explicitly violates the lepton number (L) by two units and, therefore, the observation of 0νββ would demonstrate that L is not a symmetry of nature. Combined with flavour mixing and cosmological measurements, it can provide unique contraints on neutrino mass scale and establish whether neutrinos are Dirac or Majorana particles. The Cryogenic Underground Observatory for Rare Events (CUORE) is an experiment located at the LNGS searching for 0νββ decay of 130Te. CUORE exploits the bolometric technique to reach high resolution around the Q-value (2527.5 keV). It consists of an array of 988 natural TeO2 cubic crystals grouped into 19 towers. With a total active mass of 742 kg (∼206 kg of 130Te), CUORE is operated at very low temperature with a new 3He/4He refrigerator. Data taking started at the beginning of 2017. After a brief introduction on the detector and the way data analysis is performed, I describe CUORE first results for the search of the 0νββ decay that were published in March 2018.
Published: 2019

23. Results from the cuore experiment

Author: Caminata, A, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, R, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Singh, V, Sisti, M, and Speller, D
Subjects: neutrinoless double beta decay, CUORE, Majorana Neutrino
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO 2 crystals arranged in a cylindrical compact structure of 19 towers, each of them made of 52 crystals. The construction of the experiment was completed in August 2016 and the data taking started in spring 2017 after a period of commissioning and tests. In this work we present the neutrinoless double beta decay results of CUORE from examining a total TeO 2 exposure of 86.3 kg yr, characterized by an effective energy resolution of 7.7 keV FWHM and a background in the region of interest of 0.014 counts/(keV kg yr). In this physics run, CUORE placed a lower limit on the decay half-life of neutrinoless double beta decay of 130 Te ≤ 1.3 · 10 25 yr (90% C.L.). Moreover, an analysis of the background of the experiment is presented as well as the measurement of the 130 Te 2vββ decay with a resulting half-life of T 2v1/2 = [7.9 ± 0.1 (stat.) ± 0.2 (syst.)] x 10 20 yr which is the most precise measurement of the half-life and compatible with previous results.
Published: 2019

24. First Results from CUORE: A Search for Lepton Number Violation via $0\nu\beta\beta$ Decay of $^{130}$Te

Author: CUORE Collaboration, Alduino, C., Alfonso, K., Andreotti, E., Arnaboldi, C., Avignone III, F. T., Azzolini, O., Bandac, I., Banks, T. I., Bari, G., Barucci, M., Beeman, J. W., Bellini, F., Benato, G., Bersani, A., Biare, D., Biassoni, M., Branca, A., Brofferio, C., Bryant, A., Buccheri, A., Bucci, C., Bulfon, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Capodiferro, M., Cappelli, L., Cardani, L., Carniti, P., Carrettoni, M., Casali, N., Cassina, L., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Crescentini, C., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Del Corso, F., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Di Paolo, L., Drobizhev, A., Ejzak, L., Faccini, R., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Goett, J., Gorla, P., Gotti, C., Guandalini, C., Guerzoni, M., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E. V., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Iannone, M., Kadel, R., Keppel, G., Kogler, L., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Maiano, C., Marini, L., Martinez, M., Amaya, C. Martinez, Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Olivieri, E., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pelosi, A., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Reindl, F., Rimondi, F., Risegari, L., Rosenfeld, C., Rusconi, C., Sakai, M., Sala, E., Salvioni, C., Sangiorgio, S., Santone, D., Schaeffer, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Stivanello, F., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Ventura, G., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Wise, T., Zanotti, L., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: The CUORE experiment, a ton-scale cryogenic bolometer array, recently began operation at the Laboratori Nazionali del Gran Sasso in Italy. The array represents a significant advancement in this technology, and in this work we apply it for the first time to a high-sensitivity search for a lepton-number--violating process: $^{130}$Te neutrinoless double-beta decay. Examining a total TeO$_2$ exposure of 86.3 kg$\cdot$yr, characterized by an effective energy resolution of (7.7 $\pm$ 0.5) keV FWHM and a background in the region of interest of (0.014 $\pm$ 0.002) counts/(keV$\cdot$kg$\cdot$yr), we find no evidence for neutrinoless double-beta decay. The median statistical sensitivity of this search is $7.0\times10^{24}$ yr. Including systematic uncertainties, we place a lower limit on the decay half-life of $T^{0\nu}_{1/2}$($^{130}$Te) > $1.3\times 10^{25}$ yr (90% C.L.). Combining this result with those of two earlier experiments, Cuoricino and CUORE-0, we find $T^{0\nu}_{1/2}$($^{130}$Te) > $1.5\times 10^{25}$ yr (90% C.L.), which is the most stringent limit to date on this decay. Interpreting this result as a limit on the effective Majorana neutrino mass, we find $m_{\beta\beta}<(110 - 520)$ meV, where the range reflects the nuclear matrix element estimates employed., Comment: Published in PRL, reference and DOI added
Published: 2017
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25. Search for Neutrinoless $\beta^{+}\hspace{-0.2em}EC$ Decay of $^{120}$Te with CUORE-0

Author: CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.
Subjects: Nuclear Experiment
Abstract: We have performed a search for neutrinoless $\beta^{+}\hspace{-0.2em}EC$ decay of $^{120}$Te using the final CUORE-0 data release. We describe a new analysis method for the simultaneous fit of signatures with different event topology, and of data subsets with different signal efficiency, obtaining a limit on the half-life of the decay of $T_{1/2}>1.6\cdot10^{21}$ yr at $90\%$ CI. Combining this with results from Cuoricino, a predecessor experiment, we obtain the strongest limit to date, corresponding to $T_{1/2}>2.7\cdot10^{21}$ yr at $90\%$ CI., Comment: 10 pages, 6 figures, 3 tables
Published: 2017
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26. Low Energy Analysis Techniques for CUORE

Author: CUORE Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Bari, G., Beeman, J. W., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zimmermann, S., and Zucchelli, S.
Subjects: Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract: CUORE is a tonne-scale cryogenic detector operating at the Laboratori Nazionali del Gran Sasso (LNGS) that uses tellurium dioxide bolometers to search for neutrinoless double-beta decay of $^{130}$Te. CUORE is also suitable to search for low energy rare events such as solar axions or WIMP scattering, thanks to its ultra-low background and large target mass. However, to conduct such sensitive searches requires improving the energy threshold to 10 keV. In this paper, we describe the analysis techniques developed for the low energy analysis of CUORE-like detectors, using the data acquired from November 2013 to March 2015 by CUORE-0, a single-tower prototype designed to validate the assembly procedure and new cleaning techniques of CUORE. We explain the energy threshold optimization, continuous monitoring of the trigger efficiency, data and event selection, and energy calibration at low energies in detail. We also present the low energy background spectrum of CUORE-0 below 60keV. Finally, we report the sensitivity of CUORE to WIMP annual modulation using the CUORE-0 energy threshold and background, as well as an estimate of the uncertainty on the nuclear quenching factor from nuclear recoils in CUORE-0., Comment: 11 pages, 6 figures
Published: 2017

27. CUORE opens the door to tonne-scale cryogenics experiments

Author: Adams, D.Q., Alduino, C., Alessandria, F., Alfonso, K., Andreotti, E., Avignone, F.T., III, Azzolini, O., Balata, M., Bandac, I., Banks, T.I., Bari, G., Barucci, M., Beeman, J.W., Bellini, F., Benato, G., Beretta, M., Bersani, A., Biare, D., Biassoni, M., Bragazzi, F., Branca, A., Brofferio, C., Bryant, A., Buccheri, A., Bucci, C., Bulfon, C., Camacho, A., Camilleri, J., Caminata, A., Campani, A., Canonica, L., Cao, X.G., Capelli, S., Capodiferro, M., Cappelli, L., Cardani, L., Cariello, M., Carniti, P., Carrettoni, M., Casali, N., Cassina, L., Celi, E., Cereseto, R., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Conventi, D., Copello, S., Cosmelli, C., Cremonesi, O., Crescentini, C., Creswick, R.J., Cushman, J.S., D’Addabbo, A., D’Aguanno, D., Dafinei, I., Datskov, V., Davis, C.J., Corso, F. Del, Dell’Oro, S., Deninno, M.M., Di Domizio, S., Dompè, V., Di Vacri, M.L., Di Paolo, L., Drobizhev, A., Ejzak, L., Faccini, R., Fang, D.Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fu, S.H., Fujikawa, B.K., Gaigher, R., Ghislandi, S., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Goett, J., Gorla, P., Gotti, C., Guandalini, C., Guerzoni, M., Guetti, M., Gutierrez, T.D., Haller, E.E., Han, K., Hansen, E.V., Heeger, K.M., Hennings-Yeomans, R., Hickerson, K.P., Huang, R.G., Huang, H.Z., Iannone, M., Ioannucci, L., Johnston, J., Kadel, R., Keppel, G., Kogler, L., Kolomensky, Yu.G., Leder, A., Ligi, C., Lim, K.E., Liu, R., Ma, L., Ma, Y.G., Maiano, C., Maino, M., Marini, L., Martinez, M., Amaya, C. Martinez, Maruyama, R.H., Mayer, D., Mazza, R., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P.J., Nagorny, S.S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E.B., Novati, V., Nucciotti, A., Nutini, I., O’Donnell, T., Olcese, M., Olivieri, E., Orio, F., Orlandi, D., Ouellet, J.L., Pagan, S., Pagliarone, C.E., Pagnanini, L., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pedrotta, R., Pelosi, A., Perego, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Reindl, F., Rimondi, F., Risegari, L., Rosenfeld, C., Rossi, C., Rusconi, C., Sakai, M., Sala, E., Salvioni, C., Sangiorgio, S., Santone, D., Schaeffer, D., Schmidt, B., Schmidt, J., Scielzo, N.D., Sharma, V., Singh, V., Sisti, M., Smith, A.R., Speller, D., Stivanello, F., Surukuchi, P.T., Taffarello, L., Tatananni, L., Tenconi, M., Terranova, F., Tessaro, M., Tomei, C., Ventura, G., Vetter, K.J., Vignati, M., Wagaarachchi, S.L., Wallig, J., Wang, B.S., Wang, H.W., Welliver, B., Wilson, J., Wilson, K., Winslow, L.A., Wise, T., Zanotti, L., Zarra, C., Zhang, G.Q., Zhu, B.X., Zimmermann, S., and Zucchelli, S.
Published: 2022
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28. Update on the recent progress of the CUORE experiment

Author: Collaboration, CUORE, Adams, DQ, Alduino, C, Alfonso, K, III, FT Avignone, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Domizio, S Di, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, and Santone, D
Subjects: nucl-ex, hep-ex, physics.ins-det
Abstract: CUORE is a 741 kg array of 988 TeO$_2$ bolometeric crystals designed tosearch for the neutrinoless double beta decay of $^{130}$Te and other rareprocesses. CUORE has been taking data since summer 2017, and as of summer 2018collected a total of 86.3 kg$\cdot$yr of TeO$_2$ exposure. Based on thisexposure, we were able to set a limit on the $0u\beta\beta$ half-life of$^{130}$Te of $T^{0u}_{1/2}>1.5\times10^{25}$ yr at 90% C.L. At thisconference, we showed the decomposition of the CUORE background and were ableto extract a $^{130}$Te $2u\beta\beta$ half-life of$T_{1/2}^{2u}=[7.9\pm0.1 \mathrm{(stat.)}\pm0.2\mathrm{(syst.)}]\times10^{20}$ yr. This is the most precise measurement ofthis half-life and is consistent with previous measurements.
Published: 2018

29. The CUORE and CUORE-0 experiments at LNGS

Author: Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND
Subjects: Atomic, Molecular, Nuclear, Particle and Plasma Physics, Condensed Matter Physics, Other Physical Sciences
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in August 2016 and commissioning started in fall 2016. The experiment has completed the pre-operation phase and is currently in data taking. We present here the achievements of CUORE during the commissioning phase and the limit on the 130Te half-life for the neutrinoless double beta decay that has been released after the first 3 weeks of collected data. Physics results from CUORE-0 will also be updated.
Published: 2018

30. Search for neutrinoless β+ EC decay of Te 120 with CUORE-0

Author: Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V
Subjects: nucl-ex
Abstract: We have performed a search for neutrinoless β+EC decay of Te120 using the final CUORE-0 data release. We describe a new analysis method for the simultaneous fit of signatures with different event topology, and of data subsets with different signal efficiency, obtaining a limit on the half-life of the decay of T1/2>1.6×1021 yr at 90% credibility interval (CI). Combining this with results from Cuoricino, a predecessor experiment, we obtain the strongest limit to date, corresponding to T1/2>2.7×1021 yr at 90% CI.
Published: 2018

31. Search for neutrinoless β+EC decay of Te120 with CUORE-0

Author: Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, CJ, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, G., Y, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O'Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, nucl-ex, Nuclear and plasma physics
Abstract: We have performed a search for neutrinoless β+EC decay of Te120 using the final CUORE-0 data release. We describe a new analysis method for the simultaneous fit of signatures with different event topology, and of data subsets with different signal efficiency, obtaining a limit on the half-life of the decay of T1/2>1.6×1021 yr at 90% credibility interval (CI). Combining this with results from Cuoricino, a predecessor experiment, we obtain the strongest limit to date, corresponding to T1/2>2.7×1021 yr at 90% CI.
Published: 2018

32. Study of rare nuclear processes with CUORE

Author: Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, G., Y, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, nucl-ex, physics.ins-det, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Nuclear & Particles Physics, Astronomical sciences, Nuclear and plasma physics, Particle and high energy physics
Abstract: TeO2 bolometers have been used for many years to search for neutrinoless double beta decay in 130Te. CUORE, a tonne-scale TeO2 detector array, recently published the most sensitive limit on the half-life, > 1.5 × 1025 yr, which corresponds to an upper bound of 140-400 meV on the effective Majorana mass of the neutrino. While it makes CUORE a world-leading experiment looking for neutrinoless double beta decay, it is not the only study that CUORE will contribute to in the field of nuclear and particle physics. As already done over the years with many small-scale experiments, CUORE will investigate both rare decays (such as the two-neutrino double beta decay of 130Te and the hypothesized electron capture in 123Te), and rare processes (e.g. dark matter and axion interactions). This paper describes some of the achievements of past experiments that used TeO2 bolometers, and perspectives for CUORE.
Published: 2018

33. First Results from CUORE: A Search for Lepton Number Violation via 0νββ Decay of Te130

Author: Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Arnaboldi, C, Avignone, FT, Azzolini, O, Balata, M, Bandac, I, Banks, TI, Bari, G, Barucci, M, Beeman, JW, Bellini, F, Benato, G, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Datskov, V, Davis, CJ, Del Corso, F, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Gaigher, R, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Gutierrez, TD, Haller, EE, Han, K, Hansen, EV, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Iannone, M, Ioannucci, L, Kadel, R, Keppel, G, Kogler, L, Kolomensky, Yu G, Leder, A, Ligi, C, and Lim, KE
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, CUORE Collaboration, nucl-ex, hep-ex, physics.ins-det, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract: The CUORE experiment, a ton-scale cryogenic bolometer array, recently began operation at the Laboratori Nazionali del Gran Sasso in Italy. The array represents a significant advancement in this technology, and in this work we apply it for the first time to a high-sensitivity search for a lepton-number-violating process: ^{130}Te neutrinoless double-beta decay. Examining a total TeO_{2} exposure of 86.3 kg yr, characterized by an effective energy resolution of (7.7±0.5) keV FWHM and a background in the region of interest of (0.014±0.002) counts/(keV kg yr), we find no evidence for neutrinoless double-beta decay. Including systematic uncertainties, we place a lower limit on the decay half-life of T_{1/2}^{0ν}(^{130}Te)>1.3×10^{25} yr (90% C.L.); the median statistical sensitivity of this search is 7.0×10^{24} yr. Combining this result with those of two earlier experiments, Cuoricino and CUORE-0, we find T_{1/2}^{0ν}(^{130}Te)>1.5×10^{25} yr (90% C.L.), which is the most stringent limit to date on this decay. Interpreting this result as a limit on the effective Majorana neutrino mass, we find m_{ββ}
Published: 2018

34. First Results from CUORE: A Search for Lepton Number Violation via 0νββ Decay of ^{130}Te.

Author: Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Arnaboldi, C, Avignone, FT, Azzolini, O, Balata, M, Bandac, I, Banks, TI, Bari, G, Barucci, M, Beeman, JW, Bellini, F, Benato, G, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, RJ, Cushman, JS, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Datskov, V, Davis, CJ, Del Corso, F, Dell'Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Gaigher, R, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Gutierrez, TD, Haller, EE, Han, K, Hansen, EV, Heeger, KM, Hennings-Yeomans, R, Hickerson, KP, Huang, HZ, Iannone, M, Ioannucci, L, Kadel, R, Keppel, G, Kogler, L, Kolomensky, Yu G, Leder, A, Ligi, C, and Lim, KE
Subjects: CUORE Collaboration, nucl-ex, hep-ex, physics.ins-det, General Physics, Mathematical Sciences, Physical Sciences, Engineering
Abstract: The CUORE experiment, a ton-scale cryogenic bolometer array, recently began operation at the Laboratori Nazionali del Gran Sasso in Italy. The array represents a significant advancement in this technology, and in this work we apply it for the first time to a high-sensitivity search for a lepton-number-violating process: ^{130}Te neutrinoless double-beta decay. Examining a total TeO_{2} exposure of 86.3 kg yr, characterized by an effective energy resolution of (7.7±0.5) keV FWHM and a background in the region of interest of (0.014±0.002) counts/(keV kg yr), we find no evidence for neutrinoless double-beta decay. Including systematic uncertainties, we place a lower limit on the decay half-life of T_{1/2}^{0ν}(^{130}Te)>1.3×10^{25} yr (90% C.L.); the median statistical sensitivity of this search is 7.0×10^{24} yr. Combining this result with those of two earlier experiments, Cuoricino and CUORE-0, we find T_{1/2}^{0ν}(^{130}Te)>1.5×10^{25} yr (90% C.L.), which is the most stringent limit to date on this decay. Interpreting this result as a limit on the effective Majorana neutrino mass, we find m_{ββ}
Published: 2018

35. Results from the CUORE experiment

Author: Marini, L, Adams, DQ, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, RG, Huang, HZ, Johnston, J, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Ma, YG, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, and Schmidt, B
Subjects: Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Nuclear and plasma physics, Particle and high energy physics
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment operated at about 10 mK reaching the ton-scale. CUORE main goal is the search for neutrinoless double beta decay in 130Te, while it is suitable also for other kinds of rare event searches, such as dark matter and axions. The detector is situated at Laboratori Nazionali del Gran Sasso (LNGS), Italy, and consists in an array of 988 TeO2 crystals, being both the detector and the source of the decay. Since the beginning of 2017, CUORE operations had both phases for physics data taking and campaigns of detector optimization to obtain the maximum from its potential. Here we briefly discuss one of the procedures for the optimization of the detector regarding noise reduction and report the achievements of CUORE concerning energy resolution and background in the region of interest after the first few months of data taking. Finally we conclude by examining the results from our first neutrinoless double beta decay analysis published at the beginning of 2018, which with a total TeO2 exposure of 86.3 kg·y allowed to place a lower limit on the decay half-life of T1/20ν(130Te) > 1.3 ×1025 yr (90% C.L.) .
Published: 2018

36. The CUORE bolometric detector for neutrinoless double beta decay searches

Author: Cassina, L, Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment reaching the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in 19 towers. The construction of the experiment and the installation of the detector was completed in August 2016. In this paper, the technical challenges of the construction, the design choices and measured performance of the electronic instrumentation are presented.
Published: 2018

37. Low energy analysis techniques for CUORE

Author: Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Beeman, JW, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Haller, EE, Han, K, Hansen, E, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Kadel, R, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Maino, M, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Mosteiro, PJ, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, and Sangiorgio, S
Subjects: physics.ins-det, nucl-ex, Nuclear & Particles Physics, Quantum Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Atomic, Molecular, Nuclear, Particle and Plasma Physics
Abstract: CUORE is a tonne-scale cryogenic detector operating at the Laboratori Nazionali del Gran Sasso (LNGS) that uses tellurium dioxide bolometers to search for neutrinoless double-beta decay of 130Te. CUORE is also suitable to search for low energy rare events such as solar axions or WIMP scattering, thanks to its ultra-low background and large target mass. However, to conduct such sensitive searches requires improving the energy threshold to 10 keV. In this paper, we describe the analysis techniques developed for the low energy analysis of CUORE-like detectors, using the data acquired from November 2013 to March 2015 by CUORE-0, a single-tower prototype designed to validate the assembly procedure and new cleaning techniques of CUORE. We explain the energy threshold optimization, continuous monitoring of the trigger efficiency, data and event selection, and energy calibration at low energies in detail. We also present the low energy background spectrum of CUORE-0 below 60keV. Finally, we report the sensitivity of CUORE to WIMP annual modulation using the CUORE-0 energy threshold and background, as well as an estimate of the uncertainty on the nuclear quenching factor from nuclear recoils inCUORE-0.
Published: 2017

38. Results from CUORE and CUORE-0

Author: Moggi, N, Alduino, C, Alfonso, K, Artusa, DR, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, Yu G, Leder, A, Ligi, C, Lim, KE, G., Y, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Morganti, S, Mosteiro, PJ, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Novati, V, Nucciotti, A, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, ND, and Singh, V
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and the installation of all towers in the cryostat was completed in August 2016: the experiment is now in data taking phase. In this talk, beyond updating the physics results from CUORE-0, we will discuss the achievements and technical challenges of the CUORE construction phase, with particular emphasis on the background reduction strategy, the performance of the detector during pre-operation and the projected first results from the full detector run.
Published: 2017

39. The commissioning of the CUORE experiment: The mini-tower run

Author: Copello, S, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, and Morganti, S
Abstract: © Copyright owned by the author(s). CUORE is a ton-scale experiment approaching the data taking phase in Gran Sasso National Laboratory. Its primary goal is to search for the neutrinoless double-beta decay in130Te using 988 crystals of tellurim dioxide. The crystals are operated as bolometers at about 10 mK taking advantage of one of the largest dilution cryostat ever built. Concluded in March 2016, the cryostat commissioning consisted in a sequence of cool down runs each one integrating new parts of the apparatus. The last run was performed with the fully configured cryostat and the thermal load at 4 K reached the impressive mass of about 14 tons. During that run the base temperature of 6.3 mK was reached and maintained for more than 70 days. An array of 8 crystals, called mini-tower, was used to check bolometers operation, readout electronics and DAQ. Results will be presented in terms of cooling power, electronic noise, energy resolution and preliminary background measurements.
Published: 2017

40. CUORE: First results and prospects

Author: Novati, V, Alduino, C, Alfonso, K, Avignone, FT, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, XG, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, RJ, Cushman, JS, D’Addabbo, A, D’Aguanno, D, Daﬁnei, I, Davis, CJ, Dell’Oro, S, Deninno, MM, Di Domizio, S, Di Vacri, ML, Dompè, V, Drobizhev, A, Fang, DQ, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, MA, Freedman, SJ, Fujikawa, BK, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, TD, Han, K, Heeger, KM, Hennings-Yeomans, R, Huang, HZ, Keppel, G, Kolomensky, YG, Leder, A, Ligi, C, Lim, KE, Ma, YG, Marini, L, Martinez, M, Maruyama, RH, Mei, Y, Moggi, N, Morganti, S, Nagorny, SS, Napolitano, T, Nastasi, M, Nones, C, Norman, EB, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, JL, Pagliarone, CE, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, and Scielzo, ND
Abstract: CUORE is the ﬁrst bolometric tonne-scale experiment aiming at the investigation of neutrinoless double-beta (0ν2β) decay of 130Te. The cryogenic commissioning followed by the detector installation and cool down took place during 2016. After the optimisation of all the detectors, the data-taking started in spring 2017. We report about the results of the ﬁrst dataset acquired in May, which led to a limit on the 0ν2β half-life of 130Te of 6.6×1024 yr. An upgrade of CUORE, named CUPID, is planned to improve the 0ν2β-decay sensitivity via passive and active background reduction and crystal enrichment. Some technologies for CUPID are currently under study and two of them are presented here, involving the detection of Cherenkov and scintillation light emitted by enriched 130TeO2 and Li1002MoO4 crystals respectively. This will allow us to reject the currently dominant α background.
Published: 2017

41. CUORE: The first bolometric experiment at the ton scale for the search for neutrino-less double beta decay

Author: Adams, D.Q., Alduino, C., Alfonso, K., Avignone, F.T., III, Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X.G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R.J., Cushman, J.S., D’Addabbo, A., D’Aguanno, D., Dafinei, I., Davis, C.J., Dell’Oro, S., Di Domizio, S., Dompè, V., Drobizhev, A., Fang, D.Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fujikawa, B.K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T.D., Han, K., Heeger, K.M., Huang, R.G., Huang, H.Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Ma, Y.G., Marini, L., Maruyama, R.H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nones, C., Norman, E.B., Novati, V., Nucciotti, A., Nutini, I., O’Donnell, T., Ouellet, J.L., Pagliarone, C.E., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Schmidt, B., Scielzo, N.D., Singh, V., Sisti, M., Speller, D., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S.L., Wang, B.S., Welliver, B., Wilson, J., Wilson, K., Winslow, L.A., Wise, T., Zanotti, L., Zimmermann, S., and Zucchelli, S.
Published: 2020
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42. The CUORE Bolometric Detector for Neutrinoless Double Beta Decay Searches

Author: Cassina, L., Alduino, C., Alfonso, K., Artusa, D. R., Avignone, F. T., III, Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D’Addabbo, A., D’Aguanno, D., Dafinei, I., Davis, C. J., Dell’Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Keppel, G., Kolomensky, Y. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O’Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zimmermann, S., Zucchelli, S., and Liu, Zhen-An, editor
Published: 2018
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43. CUORE: The first bolometric experiment at the ton scale for rare decay searches

Author: Adams, D.Q., Alduino, C., Alfonso, K., Avignone, F.T., III, Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X.G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R.J., Cushman, J.S., D’Addabbo, A., D’Aguanno, D., Dafinei, I., Davis, C.J., Dell’Oro, S., Deninno, M.M., Domizio, S. Di, Vacri, M.L. Di, Dompè, V., Drobizhev, A., Fang, D.Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fujikawa, B.K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T.D., Han, K., Heeger, K.M., Hennings-Yeomans, R., Huang, R.G., Huang, H.Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Ma, Y.G., Marini, L., Martinez, M., Maruyama, R.H., Mei, Y., Moggi, N., Morganti, S., Nagorny, S.S., Napolitano, T., Nastasi, M., Nones, C., Norman, E.B., Novati, V., Nucciotti, A., Nutini, I., O’Donnell, T., Ouellet, J.L., Pagliarone, C.E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Reindl, F., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Scielzo, N.D., Singh, V., Sisti, M., Speller, D., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S.L., Wang, B.S., Wang, H.W., Welliver, B., Wilson, J., Wilson, K., Winslow, L.A., Wise, T., Zanotti, L., Zhang, G.Q., Zimmermann, S., and Zucchelli, S.
Published: 2019
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44. CUORE opens the door to tonne-scale cryogenics experiments

Author: Adams, D, Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Avignone, F, Azzolini, O, Balata, M, Bandac, I, Banks, T, Bari, G, Barucci, M, Beeman, J, Bellini, F, Benato, G, Beretta, M, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Celi, E, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Datskov, V, Davis, C, Corso, F, Dell'Oro, S, Deninno, M, Di Domizio, S, Dompe, V, Di Vacri, M, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fu, S, Fujikawa, B, Gaigher, R, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Guetti, M, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, R, Huang, H, Iannone, M, Ioannucci, L, Johnston, J, Kadel, R, Keppel, G, Kogler, L, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Liu, R, Ma, L, Ma, Y, Maiano, C, Maino, M, Marini, L, Martinez, M, Amaya, C, Maruyama, R, Mayer, D, Mazza, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Nagorny, S, Napolitano, T, Nastasi, M, Nikkel, J, Nisi, S, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Olcese, M, Olivieri, E, Orio, F, Orlandi, D, Ouellet, J, Pagan, S, Pagliarone, C, Pagnanini, L, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, M, Pedrotta, R, Pelosi, A, Perego, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Reindl, F, Rimondi, F, Risegari, L, Rosenfeld, C, Rossi, C, Rusconi, C, Sakai, M, Sala, E, Salvioni, C, Sangiorgio, S, Santone, D, Schaeffer, D, Schmidt, B, Schmidt, J, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Smith, A, Speller, D, Stivanello, F, Surukuchi, P, Taffarello, L, Tatananni, L, Tenconi, M, Terranova, F, Tessaro, M, Tomei, C, Ventura, G, Vetter, K, Vignati, M, Wagaarachchi, S, Wallig, J, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Adams D. Q., Alduino C., Alessandria F., Alfonso K., Andreotti E., Avignone F. T., Azzolini O., Balata M., Bandac I., Banks T. I., Bari G., Barucci M., Beeman J. W., Bellini F., Benato G., Beretta M., Bersani A., Biare D., Biassoni M., Bragazzi F., Branca A., Brofferio C., Bryant A., Buccheri A., Bucci C., Bulfon C., Camacho A., Camilleri J., Caminata A., Campani A., Canonica L., Cao X. G., Capelli S., Capodiferro M., Cappelli L., Cardani L., Cariello M., Carniti P., Carrettoni M., Casali N., Cassina L., Celi E., Cereseto R., Ceruti G., Chiarini A., Chiesa D., Chott N., Clemenza M., Conventi D., Copello S., Cosmelli C., Cremonesi O., Crescentini C., Creswick R. J., Cushman J. S., D'Addabbo A., D'Aguanno D., Dafinei I., Datskov V., Davis C. J., Corso F. D., Dell'Oro S., Deninno M. M., Di Domizio S., Dompe V., Di Vacri M. L., Di Paolo L., Drobizhev A., Ejzak L., Faccini R., Fang D. Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fu S. H., Fujikawa B. K., Gaigher R., Ghislandi S., Giachero A., Gironi L., Giuliani A., Gladstone L., Goett J., Gorla P., Gotti C., Guandalini C., Guerzoni M., Guetti M., Gutierrez T. D., Haller E. E., Han K., Hansen E. V., Heeger K. M., Hennings-Yeomans R., Hickerson K. P., Huang R. G., Huang H. Z., Iannone M., Ioannucci L., Johnston J., Kadel R., Keppel G., Kogler L., Kolomensky Y. G., Leder A., Ligi C., Lim K. E., Liu R., Ma L., Ma Y. G., Maiano C., Maino M., Marini L., Martinez M., Amaya C. M., Maruyama R. H., Mayer D., Mazza R., Mei Y., Moggi N., Morganti S., Mosteiro P. J., Nagorny S. S., Napolitano T., Nastasi M., Nikkel J., Nisi S., Nones C., Norman E. B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Olcese M., Olivieri E., Orio F., Orlandi D., Ouellet J. L., Pagan S., Pagliarone C. E., Pagnanini L., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pedretti M., Pedrotta R., Pelosi A., Perego M., Pessina G., Pettinacci V., Piperno G., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Quitadamo S., Reindl F., Rimondi F., Risegari L., Rosenfeld C., Rossi C., Rusconi C., Sakai M., Sala E., Salvioni C., Sangiorgio S., Santone D., Schaeffer D., Schmidt B., Schmidt J., Scielzo N. D., Sharma V., Singh V., Sisti M., Smith A. R., Speller D., Stivanello F., Surukuchi P. T., Taffarello L., Tatananni L., Tenconi M., Terranova F., Tessaro M., Tomei C., Ventura G., Vetter K. J., Vignati M., Wagaarachchi S. L., Wallig J., Wang B. S., Wang H. W., Welliver B., Wilson J., Wilson K., Winslow L. A., Wise T., Zanotti L., Zarra C., Zhang G. Q., Zhu B. X., Zimmermann S., Zucchelli S., Adams, D, Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Avignone, F, Azzolini, O, Balata, M, Bandac, I, Banks, T, Bari, G, Barucci, M, Beeman, J, Bellini, F, Benato, G, Beretta, M, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Celi, E, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Datskov, V, Davis, C, Corso, F, Dell'Oro, S, Deninno, M, Di Domizio, S, Dompe, V, Di Vacri, M, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fu, S, Fujikawa, B, Gaigher, R, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Guetti, M, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, R, Huang, H, Iannone, M, Ioannucci, L, Johnston, J, Kadel, R, Keppel, G, Kogler, L, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Liu, R, Ma, L, Ma, Y, Maiano, C, Maino, M, Marini, L, Martinez, M, Amaya, C, Maruyama, R, Mayer, D, Mazza, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Nagorny, S, Napolitano, T, Nastasi, M, Nikkel, J, Nisi, S, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Olcese, M, Olivieri, E, Orio, F, Orlandi, D, Ouellet, J, Pagan, S, Pagliarone, C, Pagnanini, L, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, M, Pedrotta, R, Pelosi, A, Perego, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Reindl, F, Rimondi, F, Risegari, L, Rosenfeld, C, Rossi, C, Rusconi, C, Sakai, M, Sala, E, Salvioni, C, Sangiorgio, S, Santone, D, Schaeffer, D, Schmidt, B, Schmidt, J, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Smith, A, Speller, D, Stivanello, F, Surukuchi, P, Taffarello, L, Tatananni, L, Tenconi, M, Terranova, F, Tessaro, M, Tomei, C, Ventura, G, Vetter, K, Vignati, M, Wagaarachchi, S, Wallig, J, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Adams D. Q., Alduino C., Alessandria F., Alfonso K., Andreotti E., Avignone F. T., Azzolini O., Balata M., Bandac I., Banks T. I., Bari G., Barucci M., Beeman J. W., Bellini F., Benato G., Beretta M., Bersani A., Biare D., Biassoni M., Bragazzi F., Branca A., Brofferio C., Bryant A., Buccheri A., Bucci C., Bulfon C., Camacho A., Camilleri J., Caminata A., Campani A., Canonica L., Cao X. G., Capelli S., Capodiferro M., Cappelli L., Cardani L., Cariello M., Carniti P., Carrettoni M., Casali N., Cassina L., Celi E., Cereseto R., Ceruti G., Chiarini A., Chiesa D., Chott N., Clemenza M., Conventi D., Copello S., Cosmelli C., Cremonesi O., Crescentini C., Creswick R. J., Cushman J. S., D'Addabbo A., D'Aguanno D., Dafinei I., Datskov V., Davis C. J., Corso F. D., Dell'Oro S., Deninno M. M., Di Domizio S., Dompe V., Di Vacri M. L., Di Paolo L., Drobizhev A., Ejzak L., Faccini R., Fang D. Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fu S. H., Fujikawa B. K., Gaigher R., Ghislandi S., Giachero A., Gironi L., Giuliani A., Gladstone L., Goett J., Gorla P., Gotti C., Guandalini C., Guerzoni M., Guetti M., Gutierrez T. D., Haller E. E., Han K., Hansen E. V., Heeger K. M., Hennings-Yeomans R., Hickerson K. P., Huang R. G., Huang H. Z., Iannone M., Ioannucci L., Johnston J., Kadel R., Keppel G., Kogler L., Kolomensky Y. G., Leder A., Ligi C., Lim K. E., Liu R., Ma L., Ma Y. G., Maiano C., Maino M., Marini L., Martinez M., Amaya C. M., Maruyama R. H., Mayer D., Mazza R., Mei Y., Moggi N., Morganti S., Mosteiro P. J., Nagorny S. S., Napolitano T., Nastasi M., Nikkel J., Nisi S., Nones C., Norman E. B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Olcese M., Olivieri E., Orio F., Orlandi D., Ouellet J. L., Pagan S., Pagliarone C. E., Pagnanini L., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pedretti M., Pedrotta R., Pelosi A., Perego M., Pessina G., Pettinacci V., Piperno G., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Quitadamo S., Reindl F., Rimondi F., Risegari L., Rosenfeld C., Rossi C., Rusconi C., Sakai M., Sala E., Salvioni C., Sangiorgio S., Santone D., Schaeffer D., Schmidt B., Schmidt J., Scielzo N. D., Sharma V., Singh V., Sisti M., Smith A. R., Speller D., Stivanello F., Surukuchi P. T., Taffarello L., Tatananni L., Tenconi M., Terranova F., Tessaro M., Tomei C., Ventura G., Vetter K. J., Vignati M., Wagaarachchi S. L., Wallig J., Wang B. S., Wang H. W., Welliver B., Wilson J., Wilson K., Winslow L. A., Wise T., Zanotti L., Zarra C., Zhang G. Q., Zhu B. X., Zimmermann S., and Zucchelli S.
Abstract: The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution – comparable to semiconductor detectors – and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined.
Published: 2022

45. The CUORE Cryostat

Author: D’Addabbo, A., Alduino, C., Bersani, A., Biassoni, M., Bucci, C., Caminata, A., Canonica, L., Cappelli, L., Ceruti, G., Chott, N., Copello, S., Cremonesi, O., Cushman, J. S., D’Aguanno, D., Davis, C. J., Dell’Oro, S., Di Domizio, S., Drobizhev, A., Faverzani, M., Ferri, E., Franceschi, M. A., Gladstone, L., Gorla, P., Ligi, C., Marini, L., Napolitano, T., Nucciotti, A., Nutini, I., Ouellet, J. L., Pagliarone, C. E., Pattavina, L., Rusconi, C., Santone, D., Schmidt, B., Singh, V., Speller, D., Taffarello, L., Terranova, F., Wallig, J., Welliver, B., and Wise, T.
Published: 2018
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46. Results of cuore

Author: Auge, E, Dumarchez, J, Tron Thanh Van, J, Dell'Oro, S, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Di Domizio, S, Dompe, V, Drobizhev, A, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Ma, Y, Ma, L, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zimmermann, S, Zucchelli, S, Dell'Oro S., Adams D. Q., Alduino C., Alfonso K., Avignone F. T., Azzolini O., Bari G., Bellini F., Benato G., Biassoni M., Branca A., Brofferio C., Bucci C., Caminata A., Campani A., Canonica L., Cao X. G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R. J., Cushman J. S., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C. J., Di Domizio S., Dompe V., Drobizhev A., Fang D. Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fujikawa B. K., Giachero A., Gironi L., Giuliani A., Gorla P., Gotti C., Gutierrez T. D., Han K., Heeger K. M., Huang R. G., Huang H. Z., Johnston J., Keppel G., Kolomensky Yu. G., Leder A., Ligi C., Ma Y. G., Ma L., Marini L., Maruyama R. H., Mei Y., Moggi N., Morganti S., Napolitano T., Nastasi M., Nones C., Norman E. B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J. L., Pagliarone C. E., Pagnanini L., Pallavicini M., Pattavina L., Pavan M., Pessina G., Pettinacci V., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Schmidt B., Scielzo N. D., Singh V., Sisti M., Speller D., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S. L., Wang B. S., Welliver B., Wilson J., Wilson K., Winslow L. A., Wise T., Zanotti L., Zimmermann S., Zucchelli S., Auge, E, Dumarchez, J, Tron Thanh Van, J, Dell'Oro, S, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Di Domizio, S, Dompe, V, Drobizhev, A, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Ma, Y, Ma, L, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Singh, V, Sisti, M, Speller, D, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zimmermann, S, Zucchelli, S, Dell'Oro S., Adams D. Q., Alduino C., Alfonso K., Avignone F. T., Azzolini O., Bari G., Bellini F., Benato G., Biassoni M., Branca A., Brofferio C., Bucci C., Caminata A., Campani A., Canonica L., Cao X. G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R. J., Cushman J. S., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C. J., Di Domizio S., Dompe V., Drobizhev A., Fang D. Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fujikawa B. K., Giachero A., Gironi L., Giuliani A., Gorla P., Gotti C., Gutierrez T. D., Han K., Heeger K. M., Huang R. G., Huang H. Z., Johnston J., Keppel G., Kolomensky Yu. G., Leder A., Ligi C., Ma Y. G., Ma L., Marini L., Maruyama R. H., Mei Y., Moggi N., Morganti S., Napolitano T., Nastasi M., Nones C., Norman E. B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J. L., Pagliarone C. E., Pagnanini L., Pallavicini M., Pattavina L., Pavan M., Pessina G., Pettinacci V., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Schmidt B., Scielzo N. D., Singh V., Sisti M., Speller D., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S. L., Wang B. S., Welliver B., Wilson J., Wilson K., Winslow L. A., Wise T., Zanotti L., Zimmermann S., and Zucchelli S.
Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) at the Laboratori Nazionali del Gran Sasso, Italy, is the world's largest bolometric experiment. The detector consists of an array of 988 TeO2 crystals, for a total mass of 742 kg. CUORE is presently in data taking, searching for the neutrinoless double beta decay of 130Te. CUORE is operational since the spring of 2017. The initial science run already allowed to provide the most stringent limit on the neutrinoless double beta decay half-life of 130Te, and to perform the most precise measurement of the two-neutrino double beta decay half-life. Up to date, we have more than doubled the collected exposure. In this talk, we presenteded the most recent results and discuss the present status of the CUORE experiment.
Published: 2020

47. Initial performance of the CUORE detector

Author: Cushman, J, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Domizio, S, Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, Zucchelli, S, Cushman J. S., Alduino C., Alfonso K., Avignone F. T., Azzolini O., Bari G., Bellini F., Benato G., Bersani A., Biassoni M., Branca A., Brofferio C., Bucci C., Camacho A., Caminata A., Canonica L., Cao X. G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Cassina L., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R. J., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C. J., Dell'Oro S., Deninno M. M., Domizio S. D., Vacri M. L. D., Drobizhev A., Fang D. Q., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fujikawa B. K., Giachero A., Gironi L., Giuliani A., Gladstone L., Gorla P., Gotti C., Gutierrez T. D., Han K., Heeger K. M., Hennings-Yeomans R., Huang H. Z., Keppel G., Kolomensky Y. G., Leder A., Ligi C., Lim K. E., Ma Y. G., Marini L., Martinez M., Maruyama R. H., Mei Y., Moggi N., Morganti S., Nagorny S. S., Napolitano T., Nastasi M., Nones C., Norman E. B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J. L., Pagliarone C. E., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pessina G., Pira C., Pirro S., Pozzi S., Previtali E., Reindl F., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Santone D., Schmidt B., Schmidt J., Scielzo N. D., Singh V., Sisti M., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S. L., Wang B. S., Wang H. W., Welliver B., Wilson J., Wilson K., Winslow L. A., Wise T., Zanotti L., Zhang G. Q., Zimmermann S., Zucchelli S., Cushman, J, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Domizio, S, Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, Zucchelli, S, Cushman J. S., Alduino C., Alfonso K., Avignone F. T., Azzolini O., Bari G., Bellini F., Benato G., Bersani A., Biassoni M., Branca A., Brofferio C., Bucci C., Camacho A., Caminata A., Canonica L., Cao X. G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Cassina L., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R. J., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C. J., Dell'Oro S., Deninno M. M., Domizio S. D., Vacri M. L. D., Drobizhev A., Fang D. Q., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M. A., Freedman S. J., Fujikawa B. K., Giachero A., Gironi L., Giuliani A., Gladstone L., Gorla P., Gotti C., Gutierrez T. D., Han K., Heeger K. M., Hennings-Yeomans R., Huang H. Z., Keppel G., Kolomensky Y. G., Leder A., Ligi C., Lim K. E., Ma Y. G., Marini L., Martinez M., Maruyama R. H., Mei Y., Moggi N., Morganti S., Nagorny S. S., Napolitano T., Nastasi M., Nones C., Norman E. B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J. L., Pagliarone C. E., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pessina G., Pira C., Pirro S., Pozzi S., Previtali E., Reindl F., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Santone D., Schmidt B., Schmidt J., Scielzo N. D., Singh V., Sisti M., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S. L., Wang B. S., Wang H. W., Welliver B., Wilson J., Wilson K., Winslow L. A., Wise T., Zanotti L., Zhang G. Q., Zimmermann S., and Zucchelli S.
Abstract: CUORE, the Cryogenic Underground Observatory for Rare Events, is an experiment searching for the neutrinoless double-beta decay of 130Te. The first CUORE dataset was acquired in May and June 2017 and consisted of 10.6 kg-yr of TeO2 exposure, with several days of calibration data before and after the physics dataset. We discuss here the initial performance of the CUORE detector and cryostat in this first dataset.
Published: 2020

48. Improved Limit on Neutrinoless Double-Beta Decay in Te 130 with CUORE

Author: CUORE Collaboration, Adams, D. Q., Alduino, C., Alfonso, K., Avignone III, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Caminata, A., Campani, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Di Domizio, S., Dompè, V., Fang, D. Q., Fantini, G., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Huang, R. G., Huang, H. Z., Johnston, J., Keppel, G., Kolomensky, Yu. G., Ligi, C., Ma, Y. G., Ma, L., Marini, L., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pagnanini, L., Pallavicini, M., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Puiu, A., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Schmidt, B., Scielzo, N. D., Sharma, V., Singh, V., Sisti, M., Speller, D., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Zanotti, L., Zimmermann, S., Zucchelli, S., Adams D.Q., Alduino C., Alfonso K., Avignone F.T., Azzolini O., Bari G., Bellini F., Benato G., Biassoni M., Branca A., Brofferio C., Bucci C., Caminata A., Campani A., Canonica L., Cao X.G., Capelli S., Cappelli L., Cardani L., Carniti P., Casali N., Chiesa D., Chott N., Clemenza M., Copello S., Cosmelli C., Cremonesi O., Creswick R.J., D'Addabbo A., D'Aguanno D., Dafinei I., Davis C.J., Dell'Oro S., Di Domizio S., Dompe V., Fang D.Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M.A., Freedman S.J., Fujikawa B.K., Giachero A., Gironi L., Giuliani A., Gorla P., Gotti C., Gutierrez T.D., Han K., Heeger K.M., Huang R.G., Huang H.Z., Johnston J., Keppel G., Kolomensky Y.G., Ligi C., Ma Y.G., Ma L., Marini L., Maruyama R.H., Mei Y., Moggi N., Morganti S., Napolitano T., Nastasi M., Nikkel J., Nones C., Norman E.B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Ouellet J.L., Pagliarone C.E., Pagnanini L., Pallavicini M., Pattavina L., Pavan M., Pessina G., Pettinacci V., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Rosenfeld C., Rusconi C., Sakai M., Sangiorgio S., Schmidt B., Scielzo N.D., Sharma V., Singh V., Sisti M., Speller D., Surukuchi P.T., Taffarello L., Terranova F., Tomei C., Vignati M., Wagaarachchi S.L., Wang B.S., Welliver B., Wilson J., Wilson K., Winslow L.A., Zanotti L., Zimmermann S., Zucchelli S., Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, Adams, D, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, C, Dell’Oro, S, Di Domizio, S, Dompè, V, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Huang, R, Huang, H, Johnston, J, Keppel, G, Kolomensky, Y, Ligi, C, Ma, Y, Ma, L, Marini, L, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nikkel, J, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, J, Pagliarone, C, Pagnanini, L, Pallavicini, M, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Schmidt, B, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Speller, D, Surukuchi, P, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Zanotti, L, Zimmermann, S, Zucchelli, S, and Département de Physique des Particules (ex SPP) (DPhP)
Subjects: S076H0N, CUORE, Neutrinoless Double-Beta Decay, neutrino, cryogenics detector, background, nucleus, FOS: Physical sciences, trigger: threshold, semileptonic decay, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Neutrinoless double beta decay, neutrino physics, sensitivity, Bayesian, energy: threshold, double-beta decay: (0neutrino), mass: Majorana, S076MW, neutrino: Majorana, Nuclear Experiment (nucl-ex), Nuclear Experiment, Nuclear Physics
Abstract: We report new results from the search for neutrinoless double-beta decay in $^{130}$Te with the CUORE detector. This search benefits from a four-fold increase in exposure, lower trigger thresholds and analysis improvements relative to our previous results. We observe a background of $(1.38\pm0.07)\cdot10^{-2}$ counts$/($keV$\cdot$kg$\cdot$yr$)$ in the $0\nu\beta\beta$ decay region of interest and, with a total exposure of 372.5 kg$\cdot$yr, we attain a median exclusion sensitivity of $1.7\cdot10^{25}$ yr. We find no evidence for $0\nu\beta\beta$ decay and set a $90\%$ CI Bayesian lower limit of $3.2\cdot10^{25}$ yr on the $^{130}$Te half-life for this process. In the hypothesis that $0\nu\beta\beta$ decay is mediated by light Majorana neutrinos, this results in an upper limit on the effective Majorana mass of 75-350 meV, depending on the nuclear matrix elements used., Comment: 7 pages, 5 figures
Published: 2020
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49. P043 3-oxo-C12:2, a Quorum Sensing molecule from the gut, exerts anti-inflammatory effects through a bitter taste receptor

Author: Coquant, G, primary, Aguanno, D, additional, Brot, L, additional, Belloir, C, additional, Briand, L, additional, Grill, J P, additional, De Sordi, L, additional, Thenet, S, additional, and Seksik, P, additional
Published: 2022
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50. P064: 3-oxo-C12:2, a Quorum Sensing molecule from the gut, exerts anti-inflammatory effects through a bitter taste receptor

Author: Croquant, G., Aguanno, D., Peyrottes, A., Brot, L., Belloir, Christine, Briand, Loïc, Grill, J.P., Thenet, S., de Sordi, L., Seksik, P., Sorbonne Université (SU), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL), École normale supérieure - Paris (ENS Paris), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), and Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
Subjects: Gastroenterology, lipids (amino acids, peptides, and proteins), [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, General Medicine, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
Abstract: Background Acyl-Homoserine Lactones (AHLs) are Quorum Sensing molecules involved in the communication network of bacteria and can also have an impact on the host’s cells. We recently showed, in the gut ecosystems, the presence AHLs and among them we identified one that has never been described: 3-oxo-C12:2. This molecule was decreased in Inflammatory Bowel Disease (IBD) patients, especially during flare, and its presence was correlated to normobiosis. Interestingly, 3-oxo-C12:2 is structurally close to an AHL well described and synthesized by P. aeruginosa, 3-oxo-C12. We intent to describe 3-oxo-C12:2 effects on gut inflammation and to identified which signalling pathways are involved. Given its analogous structure to 3-oxo-C12, we hypothesized that 3-oxo-C12:2 can interact with the same cellular partners, in particular a bitter taste receptor (BTR), called T2R138, which is a GPCR expressed by immune and epithelial gut cells. Methods To test our hypothesis, we used murine macrophages cell line RAW264.7, stimulated by interferon-ɣ (IFN-g, 20U/mL) and lipopolysaccharide (LPS, 10ng/mL). We performed a transcriptome analysis using RNAseq to identify inflammatory pathways involved in the effects. Inflammatory response was monitored by measuring cytokine secretion TFNα via ELISA. Probenecid, a known allosteric inhibitor for T2R138, was used to study T2R138 role in AHL signalling. BTR screening assay was performed to extend search for 3-oxo-C12:2 receptors. Cytotoxicity was measured via Lactate Dehydrogenase release. Results After LPS/IFN-γ activation, we observed a decrease of secreted TNFα when cells are exposed to 3-oxo-C12:2, in a dose dependent manner: 15μM (-30%, p Conclusion 3-oxo-C12:2 exerts a dose dependent anti-inflammatory effect on murine immune cells. This response is partly mediated by the bitter taste receptor T2R138. This receptor is a potential target of our AHL of interest and we are currently studying the inflammatory pathways involved behind those effects. Studying the signalling between the receptor and the anti-inflammatory response would allow us to better understand the inter-kingdom dialogue between microbiota involving AHL in IBD.
Published: 2021
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