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The objective of this work is to propose a standard classification of seismic signals generated by gravitational processes and detected at close distances ( km). We review the studies where seismic instruments have been installed on unstable slopes and discuss the choice of the seismic instruments and the network geometries. Seismic observations acquired at 13 unstable slopes are analyzed in order to construct the proposed typology. The selected slopes are affected by various landslide types (slide, fall, topple and flow) triggered in various material (from unconsolidated soils to consolidated rocks). We investigate high-frequency bands (>1 Hz) where most of the seismic energy is recorded at the 1 km sensor to source distances. Several signal properties (duration, spectral content and spectrogram shape) are used to describe the sources. We observe that similar gravitational processes generate similar signals at different slopes. Three main classes can be differentiated mainly from the length of the signals, the number of peaks and the duration of the autocorrelation. The classes are the “slopequake” class, which corresponds to sources potentially occurring within the landslide body; the “rockfall” class, which corresponds to signals generated by rock block impacts; and the “granular flow” class, which corresponds to signals generated by wet or dry debris/rock flows. Subclasses are further proposed to differentiate specific signal properties (frequency content, resonance, precursory signal). The signal properties of each class and subclass are described and several signals of the same class recorded at different slopes are presented. Their potential origins are discussed. The typology aims to serve as a standard for further comparisons of the endogenous microseismicity recorded on landslides.

The eastern limestone cliff of Mount Néron (French Alps) was the theater for two medium-size rockfalls between summer and winter 2011. On 14 August 2011, a ~2000 m3 rock compartment detached from the cliff, fell 100 m below and propagated down the slope. Although most of the fallen rocks deposited on the upper part of the slope, some blocks of about 15 m in size were stopped by a ditch and an earthen barrier after a run-out of 800 m. An unstable overhanging ~2600 m3 compartment remained attached to the cliff and was blasted on 13 December 2011. During this artificially triggered event, 7 blocks reached the same ditch, with volumes ranging from 0.8 to 12 m3. A semi-permanent seismic array located about 2.5 km from the site recorded the two events, providing a unique opportunity to understand and to compare the seismic phases generated during natural and artificially triggered rockfalls. Both events have signal duration of ~100 s with comparable maximum amplitudes recorded at large distances (computed local magnitude of 1.14 and 1.05, respectively), most of the energy lying below 20 Hz. Remote sensing techniques (photogrammetry and lidar) were employed before and after the provoked rockfall, allowing the volume and fracturing to be characterized. This event was filmed by two video cameras, and the generated ground motions were recorded using two temporary 3C seismic sensors and three seismic arrays deployed at the slope toe. Videos and seismogram processing provided estimates of the propagation velocity during the successive rockfall phases, which ranges from 12 to 30 m s−1. The main seismic phases were obtained from combined video and seismic signal analyses. The two most energetic phases are related to the ground impact of fallen material after free fall, and to individual rock block impacts into the ditch and the earthen barrier. These two phases are characterized by similar low-frequency content but show very different particle motions. The discrete element technique allowed reproducing the key features of the rockfall dynamics, yielding propagation velocities compatible with experimental observations.

Rockfalls are common instabilities in alpine areas and can cause significant damage. Since high mountains have been affected by an increasing number of these phenomena in the last years, a possible correlation with permafrost degradation induced by climate change has been hypothesized. To investigate this topic, a monitoring system, made of 5 triaxial geophones and 1 thermometer, was installed in 2007 at the Carrel hut (3829 m a.s.l., Matterhorn, North-western Alps), in the frame of the Interreg IIIA Alcotra project n. 196 "Permadataroc". The preliminary data processing relates to the classification of recorded signals, the identification of the significant microseismic events and the analysis of their distribution in time and space. The first results indicated a possible correlation between clusters of events and temperature trend, and a concentration of events in specific sectors of the rock mass. Research is still in progress. The recording of data for a longer period is planned to fully understand seasonal trends and spatial distribution of microseismic activity, and possible relations with permafrost degradation. Nevertheless, the preliminary observations prove that the monitoring system can detect noises generated by rock slope deformation. Once fully developed, this technique could become a helpful tool for early warning and preliminary stability assessments.

Volume estimation of specific objects via close-range remote sensing is a complex task requiring expensive hardware and/or significant computational burden, often discouraging users potentially interested in the technology. This paper presents an innovative system for cost-effective near real-time volume estimation based on a custom platform equipped with depth and tracking cameras. Its performance has been tested in different application-oriented scenarios and compared against measurements and state-of-the-art photogrammetry. The comparison showed that the developed architecture is able to provide estimates fully comparable with the benchmark, resulting in a quick, reliable and cost-effective solution to the problem of volumetric estimates within the functioning range of the exploited sensors.

This data article provides a series of 492 stress-strain curves and compressive strength values obtained under the uniaxial compression of concrete samples fabricated from three different normal-weight concrete mixtures with four different cylindrical sample sizes ranging from 40 × 80 mm to 160 × 320 mm. These data are related to two research articles: "Revisiting statistical size effects on compressive failure of heterogeneous materials, with a special focus on concrete" (Vu et al., 2018) [1] and "Revisiting the concept of characteristic compressive strength of concrete" (Vu et al., 2020) [2]. In those papers, the strength values were used to (i) analyze and interpret statistical size effects on compressive strength of concrete (in ref. [1]), and (ii) discuss and evaluate the genuine characteristic compressive strength of concrete when size effects on strength are taken into account (in ref. [2]). This dataset could be reused for other statistical analyses on the mechanical behavior of concrete (e.g. elastic and strength properties) and associated possible mixture or size effects. In addition, the characteristic properties of the hardened concrete samples such as the apparent density, the moisture content, the modulus of elasticity as well as the internal microstructures are also provided., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships which have, or could be perceived to have, influenced the work reported in this article., (© 2020 The Authors.)

Plasticity in soft amorphous materials typically involves collective deformation patterns that emerge on intense shearing. The microscopic basis of amorphous plasticity has been commonly established through the notion of "Eshelby"-type events, localized abrupt rearrangements that induce flow in the surrounding material via nonlocal elastic-type interactions. This universal mechanism in flowing disordered solids has been proposed despite their diversity in terms of scales, microscopic constituents, or interactions. Using a numerical particle-based study, we argue that the presence of frictional interactions in granular solids alters the dynamics of flow by nucleating micro shear cracks that continually coalesce to build up system-spanning fracturelike formations on approach to failure. The plastic-to-brittle failure transition is controlled by the degree of frictional resistance which is in essence similar to the role of heterogeneities that separate the abrupt and smooth yielding regimes in glassy structures.

Acoustic emission (AE) measurements performed during the compressive loading of concrete samples with three different microstructures (aggregate sizes and porosity) and four sample sizes revealed that failure is preceded by an acceleration of the rate of fracturing events, power law distributions of AE energies and durations near failure, and a divergence of the fracturing correlation length and time towards failure. This argues for an interpretation of compressive failure of disordered materials as a critical transition between an intact and a failed state. The associated critical exponents were found to be independent of sample size and microstructural disorder and close to mean-field depinning values. Although compressive failure differs from classical depinning in several respects, including the nature of the elastic redistribution kernel, an analogy between the two processes allows deriving (finite-) sizing effects on strength that match our extensive data set. This critical interpretation of failure may have also important consequences in terms of natural hazards forecasting, such as volcanic eruptions, landslides, or cliff collapses.

Objective: We aimed to develop a model to predict unfavorable outcome in patients with acute ischemic stroke treated with intravenous thrombolytic therapy (IVT), based on simple variables present on admission., Methods: Retrospective analysis of acute ischemic stroke patients treated with IVT in a hospital in Rio de Janeiro. Clinical and radiographic variables were selected for analysis. Multivariate logistic regression was used to develop a predictive model., Results: We analyzed a total of 82 patients. Median National Institutes of Health Stroke Scale (NIHSS) on admission was 9 (3-22), 40.2% presented with a hyperdense artery sign (HAS), 62% had identifiable early parenchymal changes and 61.6% experienced a favorable outcome. An NIHSS score of > 12 on arrival, age > 70 and the presence of HAS were associated with the outcome, even after correction in a logistic regression model., Conclusion: An NIHSS > 12 on arrival, presence of HAS and age > 70 years were predictors of unfavorable outcome at three months in patients with acute ischemic stroke treated with IVT.

Internal fluid pressure often plays an important role in the rupture of brittle materials. This is a major concern for many engineering applications and for natural hazards. More specifically, the mechanisms through which fluid pressure, applied at a microscale, can enhance the failure at a macroscale and accelerate damage dynamics leading to failure remains unclear. Here we revisit the fiber bundle model by accounting for the effect of fluid under pressure that contributes to the global load supported by the fiber bundle. Fluid pressure is applied on the broken fibers, following Biot's theory. The statistical properties of damage avalanches and their evolution toward macrofailure are analyzed for a wide range of fluid pressures. The macroscopic strength of the new model appears to be strongly controlled by the action of the fluid, particularly when the fluid pressure becomes comparable with the fiber strength. The behavior remains consistent with continuous transition, i.e., second order, including for large pressure. The main change concerns the damage acceleration toward the failure that is well modeled by the concept of sweeping of an instability. When pressure is increased, the exponent β characterizing the power-law distribution avalanche sizes significantly decreases and the exponent γ characterizing the cutoff divergence when failure is approached significantly increases. This proves that fluid pressure plays a key role in failure process acting as destabilization factor. This indicates that macrofailure occurs more readily under fluid pressure, with a behavior that becomes progressively unstable as fluid pressure increases. This may have considerable consequences on our ability to forecast failure when fluid pressure is acting.

The larger structures are, the lower their mechanical strength. Already discussed by Leonardo da Vinci and Edmé Mariotte several centuries ago, size effects on strength remain of crucial importance in modern engineering for the elaboration of safety regulations in structural design or the extrapolation of laboratory results to geophysical field scales. Under tensile loading, statistical size effects are traditionally modeled with a weakest-link approach. One of its prominent results is a prediction of vanishing strength at large scales that can be quantified in the framework of extreme value statistics. Despite a frequent use outside its range of validity, this approach remains the dominant tool in the field of statistical size effects. Here we focus on compressive failure, which concerns a wide range of geophysical and geotechnical situations. We show on historical and recent experimental data that weakest-link predictions are not obeyed. In particular, the mechanical strength saturates at a nonzero value toward large scales. Accounting explicitly for the elastic interactions between defects during the damage process, we build a formal analogy of compressive failure with the depinning transition of an elastic manifold. This critical transition interpretation naturally entails finite-size scaling laws for the mean strength and its associated variability. Theoretical predictions are in remarkable agreement with measurements reported for various materials such as rocks, ice, coal, or concrete. This formalism, which can also be extended to the flowing instability of granular media under multiaxial compression, has important practical consequences for future design rules.

Objective: To identify all interventions that increase or reduce mortality in patients with acute kidney injury (AKI) and to establish the agreement between stated beliefs and actual practice in this setting., Design and Setting: Systematic literature review and international web-based survey., Participants: More than 300 physicians from 62 countries., Interventions: Several databases, including MEDLINE/PubMed, were searched with no time limits (updated February 14, 2012) to identify all the drugs/techniques/strategies that fulfilled all the following criteria: (a) published in a peer-reviewed journal, (b) dealing with critically ill adult patients with or at risk for acute kidney injury, and (c) reporting a statistically significant reduction or increase in mortality., Measurements and Main Results: Of the 18 identified interventions, 15 reduced mortality and 3 increased mortality. Perioperative hemodynamic optimization, albumin in cirrhotic patients, terlipressin for hepatorenal syndrome type 1, human immunoglobulin, peri-angiography hemofiltration, fenoldopam, plasma exchange in multiple-myeloma-associated AKI, increased intensity of renal replacement therapy (RRT), CVVH in severely burned patients, vasopressin in septic shock, furosemide by continuous infusion, citrate in continuous RRT, N-acetylcysteine, continuous and early RRT might reduce mortality in critically ill patients with or at risk for AKI; positive fluid balance, hydroxyethyl starch and loop diuretics might increase mortality in critically ill patients with or at risk for AKI. Web-based opinion differed from consensus opinion for 30% of interventions and self-reported practice for 3 interventions., Conclusion: The authors identified all interventions with at least 1 study suggesting a significant effect on mortality in patients with or at risk of AKI and found that there is discordance between participant stated beliefs and actual practice regarding these topics., (Copyright © 2013 Elsevier Inc. All rights reserved.)

We investigate compressive failure of heterogeneous materials on the basis of a continuous progressive-damage model. The model explicitly accounts for tensile and shear local damage and reproduces the main features of compressive failure of brittle materials like rocks or ice. We show that the size distribution of damage clusters, as well as the evolution of an order parameter--the size of the largest damage cluster--argue for a critical interpretation of fracture. The compressive failure strength follows a normal distribution with a very small size effect on the mean strength, in good agreement with experiments.

Aim: Paroxysmal supraventricular tachycardia (PSVT) is a very frequent type of arrhythmia. Atrioventricular nodal reciprocating tachycardia (AVNRT) and atrioventricular reciprocating tachycardia through extranodal accessory pathways (AVRT) are the most common types of paroxysmal supraventricular tachycardia. We describe our experience in diagnosing these tachycardia by electrophysiological transesophageal study (ETS)., Methods: Three hundred patients, 155 men and 145 women, (mean age, 37.2 +/- 16 years), with a history of palpitations underwent clinical evaluation and ETS. The clinical features of those with AVNRT and those with AVRT were compared., Results: Of a total of 300 patients, tachycardia was diagnosed only in 234, of which 136 (58%) had AVNRT and 98 (42%) had AVRT. AVNRT patients were older than those with AVRT (P = or < 0.004); patients with AVRT had palpitations earlier (P = or < 0.0001). Dyspnea and asthenia were the most frequent symptoms in the AVNRT patients (P = or < 0,02; P = or < 0.04). There were statistically significant differences between the two patient groups in Wencke-bach time (P = or < 0.05), ventricular-atrial (V-A) interval (P = or < 0.03) and period of induced tachycardia (P = or < 0.04)., Conclusions: ETS revealed important clinical and electrophysiological differences between patients with AVRT and those with AVNRT.

This study tested the hypotheses that chronic allergic inflammation induces not only bronchial but also lung parenchyma remodeling, and that these histologic changes are associated with concurrent changes in respiratory mechanics. For this purpose, airway and lung parenchyma remodeling were evaluated by quantitative analysis of collagen and elastin, immunohistochemistry (smooth-muscle actin expression, eosinophil, and dendritic cell densities), and electron microscopy. In vivo (airway resistance, viscoelastic pressure, and static elastance) and in vitro (tissue elastance, resistance, and hysteresivity) respiratory mechanics were also analyzed. BALB/c mice were sensitized with ovalbumin and exposed to repeated ovalbumin challenges. A marked eosinophilic infiltration was seen in lung parenchyma and in large and distal airways. Neutrophils, lymphocytes, and dendritic cells also infiltrated the lungs. There was subepithelial fibrosis, myocyte hypertrophy and hyperplasia, elastic fiber fragmentation, and increased numbers of myofibroblasts in airways and lung parenchyma. Collagen fiber content was increased in the alveolar walls. The volume proportion of smooth muscle-specific actin was augmented in distal airways and alveolar duct walls. Airway resistance, viscoelastic pressure, static elastance, and tissue elastance and resistance were significantly increased. In conclusion, prolonged allergen exposure induced remodeling not only of the airway wall but also of the lung parenchyma, leading to in vivo and in vitro mechanical changes.