29 results on '"D. Cusack"'
Search Results
2. Amalgamation of Silt Smears on Normal Faults at Outcrop Scale
- Author
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Robert P. Worthington, H. Winter, Andrew Nicol, D. Cusack, G. Watson, and Conrad Childs
- Subjects
Scale (ratio) ,Outcrop ,Silt ,Geomorphology ,Geology - Published
- 2019
3. Poster Session 4: Friday 9 December 2011, 14:00-18:00 * Location: Poster Area
- Author
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M. Wang, G. Yan, W. Yue, C. Siu, H. Tse, A. Perperidis, D. Cusack, A. White, T. Macgillivray, W. Mcdicken, T. Anderson, V. Ryabov, V. Shurupov, T. Suslova, V. Markov, N. Elmstedt, K. Ferm Widlund, B. Lind, L.-A. Brodin, M. Westgren, F. Mantovani, A. Barbieri, F. Bursi, C. Valenti, M. Quaglia, M. Modena, D. Peluso, D. Muraru, L. Dal Bianco, M. Beraldo, E. Solda', M. Tuveri, U. Cucchini, A. Al Mamary, L. Badano, S. Iliceto, A. Goncalves, C. Almeria, P. Marcos-Alberca, G. Feltes, R. Hernandez-Antolin, H. Rodriguez, L. Maroto, J. Silva Cardoso, C. Macaya, J. Zamorano, S. Squarciotta, F. Innocenti, A. Guzzo, S. Bianchi, D. Lazzeretti, E. De Villa, S. Vicidomini, B. Del Taglia, C. Donnini, R. Pini, C. Mennie, A. M. Salmasi, V. Kutyifa, V. Nagy, E. Edes, A. Apor, B. Merkely, S. Nyrnes, L. Lovstakken, H. Torp, B. Haugen, K. Said, A. Shehata, Z. Ashour, S. El-Tobgy, M. Cameli, E. Bigio, M. Lisi, F. Righini, F. Franchi, S. Scolletta, S. Mondillo, E. Gayat, L. Weinert, C. Yodwut, V. Mor-Avi, R. Lang, N. Hrynchyshyn, N. Kachenoura, B. Diebold, R. Khedim, M. Senesi, A. Redheuil, E. Mousseaux, L. Perdrix, S. Yurdakul, V. Erdemir, Y. Tayyareci, K. Memic, O. Yildirimturk, V. Aytekin, M. Gurel, S. Aytekin, L. Gargani, C. Fernandez Cimadevilla, S. La Falce, P. Landi, E. Picano, R. Sicari, M. K. Smedsrud, J. Gravning, C. Eek, L. Morkrid, H. Skulstad, L. Aaberge, B. Bendz, J. Kjekshus, T. Edvardsen, G. Bajraktari, V. Hyseni, B. Morina, A. Batalli, R. Tafarshiku, R. Olloni, M. Henein, O. Mjolstad, S. Snare, L. Folkvord, F. Helland, O. Haraldseth, A. Grimsmo, M. Berry, O. Zaghden, J. Nahum, L. Macron, O. Lairez, T. Damy, A. Bensaid, J. Dubois Rande, P. Gueret, P. Lim, N. Nciri, Z. Issaoui, C. Tlili, I. Wanes, H. Foudhil, F. Dachraoui, J. Grapsa, D. Dawson, P. Nihoyannopoulos, L. Gianturco, M. Turiel, F. Atzeni, P. Sarzi-Puttini, D. Stella, L. Donato, L. Tomasoni, P. Jung, M. Mueller, T. Huber, G. Sevilmis, F. Kroetz, H. Sohn, V. Panoulas, A. Bratsas, R. Raso, G. Tartarisco, G. Pioggia, P. Gargiulo, M. Petretta, A. Cuocolo, M. Prastaro, C. D'amore, E. Vassallo, G. Savarese, C. Marciano, S. Paolillo, P. Perrone Filardi, C. Aggeli, I. Felekos, G. Roussakis, E. Poulidakis, P. Pietri, K. Toutouzas, C. Stefanadis, A. Kaladaridis, I. Skaltsiotis, G. Kottis, D. Bramos, D. Takos, I. Matthaios, I. Agrios, E. Papadopoulou, S. Moulopoulos, S. Toumanidis, P. Carrilho-Ferreira, N. Cortez-Dias, C. Jorge, D. Silva, J. Silva Marques, R. Placido, L. Santos, S. Ribeiro, M. Fiuza, F. Pinto, V. Stoickov, S. Ilic, M. Deljanin Ilic, W. Kim, J. Woo, J. Bae, K. Kim, M. Descalzo, J. Rodriguez, S. Moral, I. Otaegui, P. Mahia, L. Garcia Del Blanco, T. Gonzalez Alujas, J. Figueras, A. Evangelista, D. Garcia-Dorado, M. Takeuchi, K. Kaku, K. Otani, M. Iwataki, H. Kuwaki, N. Haruki, H. Yoshitani, Y. Otsuji, M. Kukucka, M. Pasic, A. Unbehaun, S. Dreysse, A. Mladenow, H. Kuppe, R. Hetzer, N. Rajamannan, A. Tanrikulu, L. Kristiansson, S. Gustafsson, K. Lindmark, M. Y. Henein, C. Evdoridis, P. Stougiannos, M. Thomopoulos, M. Fosteris, P. Spanos, G. Sionis, D. Giatsios, A. Paschalis, C. Sakellaris, A. Trikas, Z. Y. Yong, K. Boerlage-Van Dijk, K. Koch, M. Vis, B. Bouma, J. Piek, J. Baan, L. Abid, Z. Frikha, K. Makni, N. Maazoun, D. Abid, M. Hentati, S. Kammoun, P. Barbier, A. Staron, C. Cefalu', G. Berna, P. Gripari, D. Andreini, G. Pontone, M. Pepi, L. Ring, B. Rana, S. Ho, F. Wells, A. Dogan, O. Karaca, G. Guler, E. Guler, H. Gunes, E. Alizade, H. Agus, G. Gol, O. Esen, A. Esen, M. Turkmen, E. Agricola, G. Ingallina, M. Ancona, S. Maggio, M. Slavich, V. Tufaro, M. Oppizzi, A. Margonato, C. Orsborne, B. Irwin, K. Pearce, S. Ray, C. Garcia Alonso, N. Vallejo, C. Labata, J. Lopez Ayerbe, A. Teis, E. Ferrer, R. Nunez Aragon, F. Gual, M. Pedro Botet, A. Bayes Genis, C. M. Santos, M. Carvalho, M. Andrade, H. Dores, S. Madeira, G. Cardoso, A. Ventosa, C. Aguiar, R. Ribeiras, M. Mendes, M. Petrovic, G. Milasinovic, B. Vujisic-Tesic, I. Nedeljkovic, D. Zamaklar-Trifunovic, I. Petrovic, G. Draganic, M. Banovic, M. Boricic, H. Villarraga, C. Molini-Griggs Bs, P. Silen-Rivera Bs, B. Payne Mph Ms, Y. Koshino Md Phd, J. Hsiao Md, V. Monivas Palomero, S. Mingo Santos, C. Mitroi, I. Garcia Lunar, P. Garcia Pavia, V. Castro Urda, J. Toquero, J. Gonzalez Mirelis, M. Cavero Gibanel, I. Fernandez Lozano, Z. Oko-Sarnowska, H. Wachowiak-Baszynska, A. Katarzynska-Szymanska, O. Trojnarska, S. Grajek, D. Bellavia, P. Pellikka, A. Dispenzieri, J. K. Oh, V. Polizzi, F. Pitrolo, F. Musumeci, F. Miller, R. Ancona, S. Comenale Pinto, P. Caso, S. Severino, C. Cavallaro, F. Vecchione, A. D'onofrio, R. Calabro', A. M. Maceira Gonzalez, C. Ripoll, J. Cosin-Sales, B. Igual, J. Salazar, V. Belloch, J. Cosin-Aguilar, B. Pinamonti, A. Iorio, M. Bobbo, M. Merlo, G. Barbati, L. Massa, G. Faganello, A. Di Lenarda, G. F. Sinagra, T. Ishizu, Y. Seo, M. Enomoto, Y. Kameda, N. Ishibashi, M. Inoue, K. Aonuma, A. Saleh, A. Matsumori, H. Negm, H. Fouad, A. Onsy, E. Hamodraka, I. Paraskevaidis, M. Kallistratos, V. Lezos, T. Zamfir, C. Manetos, D. Mavropoulos, L. Poulimenos, D. Kremastinos, A. Manolis, R. Citro, F. Rigo, Q. Ciampi, M. Patella, G. Provenza, C. Zito, E. Tagliamonte, F. Rotondi, F. Silvestri, E. Bossone, P. Beltran Correas, C. Gutierrez Landaluce, M. Gomez Bueno, J. Segovia Cubero, C. Beladan, F. Matei, B. Popescu, A. Calin, M. Rosca, A. Boanta, R. Enache, O. Savu, C. Usurelu, C. Ginghina, A. O. Ciobanu, R. Dulgheru, S. Magda, R. Dragoi, M. Florescu, D. Vinereanu, S. Robalo Martins, C. Calisto, S. Goncalves, I. Barrigoto, J. Carvalho De Sousa, A. Almeida, A. Nunes Diogo, L. Sargento, M. Satendra, C. Sousa, N. Lousada, R. Palma Reis, V. Schiano Lomoriello, R. Esposito, A. Santoro, R. Raia, P. Schiattarella, E. Dores, M. Galderisi, N. Mansencal, V. Caille, A. Dupland, S. Perrot, K. Bouferrache, A. Vieillard-Baron, R. Jouffroy, P. Moceri, E. Liodakis, M. Gatzoulis, W. Li, K. Dimopoulos, M. Sadron, P. E. Seguela, B. Arnaudis, Y. Dulac, T. Cognet, P. Acar, Y. Shiina, H. Uemura, K. Kupczynska, J. Kasprzak, B. Michalski, P. Lipiec, V. Carvalho, A. M. G. Almeida, C. David, J. Marques, P. Ferreira, M. Amaro, P. Costa, A. Diogo, V. Tritakis, I. Ikonomidis, J. Lekakis, S. Tzortzis, N. Kadoglou, I. Papadakis, P. Trivilou, C. Koukoulis, M. Anastasiou-Nana, T. Bombardini, S. Gherardi, G. Arpesella, M. Maccherini, W. Serra, G. Magnani, R. Del Bene, E. Pasanisi, U. Startari, L. Panchetti, A. Rossi, M. Piacenti, M. Morales, I. El Hajjaji, R. El Mahmoud, F. Digne, O. Dubourg, G. Agoston, A. Moreo, L. Pratali, A. Moggi Pignone, A. Pavellini, M. Doveri, F. Musca, A. Varga, F. Faita, S. Rimoldi, C. Sartori, Y. Alleman, C. Salinas Salmon, M. Villena, U. Scherrer, R. Baptista, S. Serra, G. Castro, R. Martins, M. Salvador, P. Monteiro, J. Silva, L. Szudi, A. Temesvary, B. Fekete, I. Kassai, L. Szekely, S. S. Abdel Moneim, M. Martinez, S. Mankad, M. Bernier, A. Dhoble, K. Chandrasekaran, J. Oh, S. Mulvagh, G. R. Hong, J. Y. Kim, S. C. Lee, S. H. Choi, I. S. Sohn, H. S. Seo, J. H. Choi, K. I. Cho, S. J. Yoon, S. J. Lim, P. Wejner-Mik, J. Kusmierek, A. Plachcinska, R. Szuminski, S. Stoebe, A. Tarr, T. Trache, A. Hagendorff, C. Jenkins, H. Kuhl, H. Nesser, T. Marwick, A. Franke, J. Niel, L. Sugeng, S. Soderberg, P. Lindqvist, J. Necas, S. Kovalova, S. K. Saha, A. Kiotsekoglou, R. Toole, S. Govind, A. Gopal, M.-S. Amzulescu, A. Florian, J. Bogaert, S. Janssens, J. Voigt, V. Parisi, M. Losi, L. Parrella, C. Contaldi, E. Chiacchio, A. Caputi, A. Scatteia, A. Buonauro, S. Betocchi, R. Rimbas, S. Mihaila, M. Caputo, R. Navarri, P. Innelli, R. Urselli, E. Capati, P. Ballo, F. Furiozzi, R. Favilli, R. Lindquist, A. Miller, C. Reece, P. O'leary, F. Cetta, B. W. Eidem, M. Cikes, H. Gasparovic, B. Bijnens, V. Velagic, T. Kopjar, B. Biocina, D. Milicic, A. Ta-Shma, A. Nir, Z. Perles, S. Gavri, J. Golender, A. Rein, G. Pinnacchio, L. Barone, I. Battipaglia, A. Cosenza, L. Marinaccio, I. Coviello, G. Scalone, A. Sestito, G. Lanza, F. Crea, S. Cakal, E. Eroglu, B. Ozkan, S. Kulahcioglu, M. Bulut, A. Koyuncu, G. Acar, G. Alici, C. Dundar, F. Labombarda, E. Zangl, A. Pellissier, D. Bougle, P. Maragnes, P. Milliez, E. Saloux, S. Lagoudakou, E. Gialafos, A. Tsokanis, A. Nagy, T. Kovats, H. Vago, A. Toth, B. Sax, A. Kovacs, M. F. Elnoamany, H. Badran, I. Abdelfattah, T. Khalil, M. Salama, T. Butz, C. Taubenberger, F. Thangarajah, A. Meissner, M. Van Bracht, M. Prull, H. Yeni, G. Plehn, H. Trappe, R. Rydman, D. Bone, M. Alam, K. Caidahl, F. Larsen, Z. Gasior, Z. Tabor, P. Sengupta, D. Liu, M. Niemann, K. Hu, S. Herrmann, S. Stoerk, C. Morbach, S. Knop, W. Voelker, G. Ertl, F. Weidemann, P. Cawley, C. Hamilton-Craig, L. Mitsumori, J. Maki, C. Otto, M. Astrom Aneq, E. Nylander, T. Ebbers, J. Engvall, P. Arvanitis, F. Flachskampf, O. Duvernoy, F. De Torres Alba, S. Valbuena Lopez, G. Guzman Martinez, J. Gomez De Diego, J. Rey Blas, E. Armada Romero, E. Lopez De Sa, M. Moreno Yanguela, J. Lopez Sendon, N. Trikalinos, G. Siasos, A. Aggeli, A. Tomaszewski, A. Kutarski, M. Tomaszewski, O. Vriz, C. Driussi, M. Bettio, D. Pavan, F. Antonini Canterin, A. Doltra Magarolas, J. Fernandez-Armenta, E. Silva, N. Solanes, M. Rigol, A. Barcelo, L. Mont, A. Berruezo, J. Brugada, M. Sitges, F. L. Ciciarello, S. Mandolesi, F. Fedele, L. Agati, A. Marceca, S. Rhee, S. Shin, S. Kim, K. Yun, N. Yoo, N. Kim, S. Oh, J. Jeong, and N. Alabdulkarim
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education.field_of_study ,medicine.medical_specialty ,business.industry ,Multiple sclerosis ,Population ,Hemodynamics ,General Medicine ,Cerebro ,medicine.disease ,Internal medicine ,Cardiology ,Medicine ,Radiology, Nuclear Medicine and imaging ,Cardiology and Cardiovascular Medicine ,education ,business - Published
- 2011
4. The National Exposure Registry: history and lessons learned
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Myron G, Schultz, James H, Sapp, Caroline D, Cusack, and Jennifer M, Fink
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Benzene ,Environmental Exposure ,History, 20th Century ,Dioxins ,United States ,Trichloroethylene ,Solvents ,Humans ,Environmental Pollutants ,Trichloroethanes ,Public Health ,Registries ,Biomarkers ,Program Evaluation - Abstract
The National Exposure Registry (NER) was created as a comprehensive group of data repositories that sought, over time, to relate specific environmental exposures to dioxin, trichloroethylene (TCE), benzene, and trichloroethane (TCA) to registrants' health conditions. Some parts of the NER were well conceived, whereas others were not. The most important design deficiency of the NER was its inability to adequately assess exposure. This was the key missing element and the Achilles heel of the NER program. At least three other important issues were never satisfactorily resolved in the design of the NER. They were unverified self-reporting, appropriate control groups, and the use of biomarkers. The many health effects that were observed to be in excess when compared with national norms might be explained by methodological differences in data analysis and reliance on self-reported nonverified data. Creating and maintaining a population-based chemical exposure registry is a more difficult challenge than creating and maintaining an outcome registry, such as a cancer registry.
- Published
- 2010
5. Case/control study of the role of splenectomy in chronic lymphocytic leukemia
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Susan Lerner, John F. Seymour, M J Keating, Raphael E. Pollock, and J D Cusack
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Adult ,Male ,Cancer Research ,medicine.medical_specialty ,medicine.medical_treatment ,Chronic lymphocytic leukemia ,Splenectomy ,Atelectasis ,Internal medicine ,medicine ,Humans ,Aged ,Retrospective Studies ,Performance status ,business.industry ,Retrospective cohort study ,Hemoglobin A ,Perioperative ,Organ Size ,Middle Aged ,medicine.disease ,Leukemia, Lymphocytic, Chronic, B-Cell ,Hematologic Response ,Surgery ,Leukemia ,Oncology ,Case-Control Studies ,Splenomegaly ,Female ,Morbidity ,business - Abstract
PURPOSE This retrospective analysis was performed to evaluate critically the morbidity and mortality of splenectomy in patients with chronic lymphocytic leukemia and to determine the probability of hematologic response. Further, using a case/control format based on multivariate analysis-derived predictors of survival, we evaluated the influence of splenectomy on survival. PATIENTS AND METHODS Between 1971 and 1993, 55 patients with chronic lymphocytic leukemia underwent splenectomy. They were compared with 55 fludarabine-treated patients who had been matched for age, serum albumin level, sex, hemoglobin level, Rai stage, number of prior therapies, and time from diagnosis. RESULTS In the perioperative period, blood-product usage was modest, and common morbidities were limited to minor infections in 18% of the patients and pneumonia/atelectasis in 25%. Perioperative mortality was 9%. Deaths were related to septic complications in all cases and associated with a preoperative performance status > or = 2 (P = .05). The only predictor identified for hemoglobin and neutrophil increments was spleen weight (P < .05). No factors predictive of platelet increment were identified. The early death rate (within 30 days) and overall survival of splenectomy and control patients were not significantly different (P > .2). Among Rai stage IV patients, those who were splenectomized displayed a strong trend for improved overall survival (P = .15 by log-rank test). The 2-year actuarial survival rate of Rai stage IV patients was 51% +/- 9% in the splenectomy group and 28% +/- 9% in the control group. CONCLUSION Splenectomy can be performed with modest morbidity, mortality, and resource utilization in patients with advanced chronic lymphocytic leukemia and significant cytopenias. The procedure results in major hematologic benefits in most patients, with hemoglobin and neutrophil increments correlated with spleen weight. Overall, the survival of splenectomized patients is equivalent to control patients. Thrombocytopenic patients (< 100 x 10(9)/L) are most likely to obtain hematologic benefit, and potentially enjoy improved survival. These patients would be suitable for a randomized study to establish definitively the role of splenectomy in chronic lymphocytic leukemia.
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- 1997
6. The behavioral consequences of a communication intervention on institutionalized residents with aphasia and dysarthria
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K C, Buckwalter, D, Cusack, M, Beaver, E, Sidles, and K, Wadle
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Male ,Behavior Therapy ,Dysarthria ,Aphasia ,Language Therapy ,Homes for the Aged ,Humans ,Middle Aged ,Speech Therapy ,Combined Modality Therapy ,Speech Disorders ,Aged ,Nursing Homes - Published
- 1988
7. HEMATOMA OF THE RECTUS ABDOMINIS MUSCLE SIMULATING AN ACUTE ABDOMEN IN PREGNANCY
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J D, CUSACK and F C, LAWLER
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Abdomen, Acute ,Diagnosis, Differential ,Pregnancy Complications ,Hematoma ,Pregnancy ,Abdomen ,Abdominal Wall ,Pregnancy Complications, Cardiovascular ,Rectus Abdominis ,Humans ,Abdominal Cavity ,Female - Published
- 1964
8. Systematic hand-held echocardiography in patients hospitalized with acute coronary syndrome.
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Geers J, Balfour A, Molek P, Barron P, Botezatu S, Joshi SS, White A, Buchwald M, Everett R, McCarley J, Cusack D, Japp AG, Gibson PH, Lang CCE, Stirrat C, Grubb NR, Bing R, Cruden NL, Denvir MA, Soliman Aboumarie H, Cosyns B, Newby DE, and Dweck MR
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- Humans, Male, Female, Aged, Middle Aged, Feasibility Studies, Hospitalization, Cohort Studies, Acute Coronary Syndrome diagnostic imaging, Echocardiography methods
- Abstract
Aims: Transthoracic echocardiography is recommended in all patients with acute coronary syndrome but is time-consuming and lacks an evidence base. We aimed to assess the feasibility, diagnostic accuracy, and time efficiency of hand-held echocardiography in patients with acute coronary syndrome and describe the impact of echocardiography on clinical management in this setting., Methods and Results: Patients with acute coronary syndrome underwent both hand-held and transthoracic echocardiographies with agreement between key imaging parameters assessed using kappa statistics. The immediate clinical impact of hand-held echocardiography in this population was systematically evaluated. Overall, 262 patients (65 ± 12 years, 71% male) participated. Agreement between hand-held and transthoracic echocardiographies was good-to-excellent (kappa 0.60-1.00) with hand-held echocardiography having an overall negative predictive value of 95%. Hand-held echocardiography was performed rapidly (7.7 ± 1.6 min) and completed a median of 5 (interquartile range 3-20) h earlier than transthoracic echocardiography. Systematic hand-held echocardiography in all patients with acute coronary syndrome identified an important cardiac abnormality in 50%, and the clinical management plan was changed by echocardiography in 42%. In 85% of cases, hand-held echocardiography was sufficient for patient decision-making, and transthoracic echocardiography was no longer deemed necessary., Conclusion: In patients with acute coronary syndrome, hand-held echocardiography provides comparable results to transthoracic echocardiography, can be more rapidly applied, and gives sufficient imaging information for decision-making in the vast majority of patients. Systematic echocardiography has clinical impact in half of patients, supporting the clinical utility of echocardiography in this population and providing an evidence base for current guidelines., Competing Interests: Conflict of interest: None declared., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.)
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- 2024
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9. Current status of undergraduate teaching in forensic & legal medicine in Europe.
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Payne-James J, Payne-James G, Cecchi R, Cusack D, Keller E, Ludes B, Madea B, Väli M, Vieira DN, and Sajantila A
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- Humans, Europe, Surveys and Questionnaires, Curriculum, Education, Medical, Undergraduate, Forensic Medicine education
- Abstract
The European Council of Legal Medicine (ECLM) is the body established in 1992 to represent practitioners forensic & legal medicine and is composed of delegates of the countries of the European Union (EU) and from other countries which form part of Europe to a current total of 34 member countries. The aims of this study were to determine the current status of undergraduate forensic & legal medicine teaching in the curriculum of medical studies in ECLM countries and to use the results of this study to determine whether it would be appropriate to develop new guidelines and standards for harmonising the content of undergraduate forensic medicine training across ECLM member countries. A detailed questionnaire was sent to all individuals or organisations listed on the ECLM contact database. Responses were received from 21 of 33 countries on the database. These responses showed considerable emphasis on undergraduate teaching of forensic medicine in all countries with the exception of Belgium and the United Kingdom. There was great general consistency in the subjects taught. The data from this survey provide a baseline which should assist in developing a strategy to harmonise forensic & legal medicine undergraduate training in member countries of the ECLM. The ECLM is now in a good position to establish a pan-European working group to coordinate a consensus document identifying an appropriate and modern core undergraduate forensic medicine curriculum that can be presented to the medical education authorities in each country, and which can be adapted for local requirements, based on available personnel, the forensic medicine structure in the country, and most importantly, the needs of the local population., (© 2024. The Author(s).)
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- 2024
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10. European Council of Legal Medicine (ECLM) on-site inspection forms for forensic pathology, anthropology, odontology, genetics, entomology and toxicology for forensic and medico-legal scene and corpse investigation: the Parma form.
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Cecchi R, Cusack D, Ludes B, Madea B, Vieira DN, Keller E, Payne-James J, Sajantila A, Vali M, Zoia R, Cucurachi N, Schirripa ML, Marezza F, Anzillotti L, Donato L, Cattaneo C, Favretto D, Pelotti S, Pinchi V, Vanin S, and Gherardi M
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- Anthropology, Cadaver, Forensic Pathology, Humans, Entomology, Forensic Medicine methods
- Abstract
Further to a previous publication by the European Council of Legal Medicine (ECLM) concerning on-site forensic and medico-legal scene and corpse investigation, this publication provides guidance for forensic medical specialists, pathologists and, where present, coroners' activity at a scene of death inspection and to harmonize the procedures for a correct search, detection, collection, sampling and storage of all elements which may be useful as evidence, and ensure documentation of all these steps. This ECLM's inspection form provides a checklist to be used on-site for the investigation of a corpse present at a crime or suspicious death scene. It permits the collection of all relevant data not only for the pathologist, but also for forensic anthropologists, odontologists, geneticists, entomologists and toxicologists, thus supporting a collaborative work approach. Detailed instructions for the completion of forms are provided., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2022
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11. A clinical investigation into the ability of subjects with lung disease to provide breath specimens using the EvidenzerIRL evidential breath analyser in alcohol intoxicant driving in criminal justice evidence.
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Dowling S, Reynolds D, O'Reilly A, Nolan G, Kranidi A, Gallagher CG, and Cusack D
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- Aged, Case-Control Studies, Central Nervous System Depressants analysis, Ethanol analysis, Female, Humans, Male, Middle Aged, Respiratory Function Tests, Substance Abuse Detection instrumentation, Breath Tests instrumentation, Driving Under the Influence, Lung Diseases complications
- Abstract
The EvidenzerIRL instrument has been in use as an evidential breath analyser in the application of drink driving laws in the Republic of Ireland since 2011. The result of the analysis is used as evidence in prosecutions before the Courts in per se offences of driving under the influence of alcohol as distinct from screening results at the roadside. This study aims to assist doctors, lawyers and judges in assessing drivers' failure to provide valid evidential breath specimens. Since the introduction of the EvidenzerIRL, approximately 10% of evidential breath tests annually result in failure or refusal to provide a successful breath specimen, this is an offence under Irish road traffic laws. The presence of lung disease has been given as a reason for the driver failing to provide evidential breath specimens. The aim of this study is to assess the ability of subjects with lung disease to provide breath specimens using the EvidenzerIRL. Pulmonary function tests (PFT) were carried out on volunteers from outpatients of the pulmonary laboratory in St Vincent's University Hospital, Dublin (n = 58) and a control group with no underlying lung disease (n = 19). After the PFTs all volunteers were asked to provide breath specimens using the EvidenzerIRL. Fourteen (24%) out of 58 lung disease volunteers failed to provide a breath specimen, no one from the control group was unsuccessful. Thirteen females and one male volunteer could not successfully provide. Female volunteers were more likely to fail to provide than male volunteers. A significant difference was found between the median age of successful (62.2 years) and unsuccessful (69.2 years) lung disease volunteers. Only one PFT, percentage predicted of Forced Expiratory Volume in 1 second (FEV
1 ), had a significant difference between the mean of successful (86.6%) and unsuccessful (66.5%) lung disease volunteers. A subject with lung disease was more likely to be successful than unsuccessful. Drivers' effort and operators' guidance through the process were found to be crucial parts to a successful outcome., (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)- Published
- 2021
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12. The Ecology Underground coalition: building a collaborative future of belowground ecology and ecologists.
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Defrenne CE, Abs E, Longhi Cordeiro A, Dietterich L, Hough M, Jones JM, Kivlin SN, Chen W, Cusack D, Franco ALC, Khasanova A, Stover D, and Romero-Olivares AL
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- Ecology, Ecosystem
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- 2021
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13. A clinical investigation into the ability of subjects with a lung disease to provide breath specimens using the Dräger 6510.
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Dowling S, Reynolds D, O'Reilly A, Nolan G, Gallagher C, and Cusack D
- Subjects
- Adult, Aged, Aged, 80 and over, Bronchodilator Agents therapeutic use, Case-Control Studies, Driving Under the Influence legislation & jurisprudence, Female, Humans, Male, Middle Aged, Respiratory Function Tests, Young Adult, Breath Tests instrumentation, Lung Diseases drug therapy, Substance Abuse Detection instrumentation
- Abstract
In the enforcement of drink driving laws failing to provide a breath specimen for alcohol analysis at the roadside when requested by a Police Officer is an offence in many countries. Some drivers claim that a lung disease prevented their ability to be successful. This study aims to investigate the relationship between the presence of a lung disease and the ability to provide a successful breath specimen using the Dräger 6510 screening device. Sixty participants with lung disease and nineteen control participants underwent pulmonary function tests and were then tested with a Dräger 6510 screening device. Only one participant was unsuccessful using the Dräger 6510, this participant suffered from interstitial lung disease. The pulmonary function test results did not indicate if someone would be successful or how many attempts would be needed to be successful. The presence of a lung disease did not indicate if a driver would be unsuccessful however all participants were free from infection and the participants with a lung disease were stable at the time of testing. Correct instruction, subject cooperation and the technique used by the driver to provide a breath specimen were found to be important factors in the success of a breath test., Competing Interests: Declaration of competing interest None., (Copyright © 2020 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF
14. European council of legal medicine (ECLM) guidelines for the examination of suspected elder abuse.
- Author
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Keller E, Santos C, Cusack D, Väli M, Ferrara D, Ludes B, Mangin P, Payne-James JJ, and Vieira DN
- Subjects
- Aged, Europe, Geriatric Assessment, Humans, Informed Consent, Medical History Taking, Surveys and Questionnaires, Elder Abuse diagnosis, Elder Abuse legislation & jurisprudence
- Abstract
Article 25 of the Charter of Fundamental Rights of the European Union (adopted in Nice on 7 December 2000) recognizes and respects the rights of older people to lead a life of dignity and independence and to participate in social and cultural life. It also highlights the importance of prevention and recognition of elder abuse, especially since exposure to violence is likely as the population ages, either in familial or in institutional settings. Elder abuse has some issues in common with child abuse but in spite of this fact currently is less recognized. Health professionals have a major role to play in early detection and management of cases of elder abuse. This protocol summarizes some key concepts and approaches to assist in the timely detection and investigation of elder abuse cases by healthcare professionals and forensic practitioners.
- Published
- 2019
- Full Text
- View/download PDF
15. Guidelines examination of victims of sexual assault harmonization of forensic and medico-legal examination of persons.
- Author
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Ludes B, Geraut A, Väli M, Cusack D, Ferrara D, Keller E, Mangin P, and Vieira DN
- Subjects
- Documentation standards, Female, Humans, Male, Medical History Taking, Specimen Handling standards, Crime Victims, Forensic Medicine standards, Physical Examination standards, Sex Offenses
- Abstract
Sexual assault is a complex situation with medical, psychological, and legal aspects. Forensic experts play a major role in terms of forensic and gynecological medical examination and evidence collection in order to maintain the chain of custody. Victims should be examined by a specially trained medico-legal examiner in order to avoid multiple examinations in the surroundings that do not meet minimum health standards. The evolution and treatment of sexual assault victims are time-intensive and should optimally be provided by a team that includes a forensic medical doctor. These guidelines will be of interest to forensic medical doctors who will have responsibility for the examination and assessment of victims of sexual violence and can be used as a day-to-day service document and/or a guide to develop health service for victims of sexual violence.
- Published
- 2018
- Full Text
- View/download PDF
16. An atmospheric pressure chemical ionisation liquid chromatographic-tandem mass spectrometry method for the analysis of benzodiazepines in urine.
- Author
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Dunlop S, Hayes K, Leavy P, Cusack D, and Maguire R
- Subjects
- Humans, Limit of Detection, Linear Models, Reproducibility of Results, Benzodiazepines urine, Chromatography, Liquid methods, Tandem Mass Spectrometry methods
- Abstract
The objective of this work was to establish an analytical method for the analysis of 7 Benzodiazepines (diazepam, oxazepam, temazepam, nordiazepam, desalkylflurazepam, alprazolam and α-hydroxyalprazolam) in urine specimens taken from drivers suspected of driving under the influence of drugs. The specimen, calibrator and control preparation involved hydrolysis of conjugated benzodiazepines using β-glucuronidase in sodium acetate buffer, with incubation at 60°C for 2h. Specimens were then centrifuged, before being diluted 1 in 5 (total dilution 1 in 10), with 10% acetonitrile in water. Specimens were analysed using a Shimadzu Prominence UPLC coupled to an AB Sciex 4000 QTrap LC-MS-MS. The chromatographic column was a Shim-pack XR ODS 2.2μm. 3.0×50mm column and the mobile phase was a binary gradient system comprising of mobile phase A which was an ammonium formate/formic acid buffer dissolved in water and mobile phase B which was an ammonium formate/formic acid buffer dissolved in Acetonitrile. APCI was selected as the ionisation technique and the MS was operated in MRM mode, monitoring 2 transitions per analyte. The validation of the method is described. The method was found to be linear, accurate and precise (within day and between day) for diazepam, oxazepam, temazepam, nordiazepam, desalkylflurazepam, alprazolam and α-hydroxyalprazolam. The results of 480 cases are reviewed and show that alprazolam use was found in 35% of cases. Use of benzodiazepines resulting in oxazepam, nordiazepam or temazepam were found ca. 70% of cases analysed., (Copyright © 2017 Elsevier B.V. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
17. Dynamic Enhancement of B-Mode Cardiac Ultrasound Image Sequences.
- Author
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Perperidis A, Cusack D, White A, McDicken N, MacGillivray T, and Anderson T
- Subjects
- Humans, Reproducibility of Results, Sensitivity and Specificity, Algorithms, Echocardiography methods, Heart Ventricles diagnostic imaging, Image Enhancement methods, Image Interpretation, Computer-Assisted methods
- Abstract
Limited contrast, along with speckle and acoustic noise, can reduce the diagnostic value of echocardiographic images. This study introduces dynamic histogram-based intensity mapping (DHBIM), a novel approach employing temporal variations in the cumulative histograms of cardiac ultrasound images to contrast enhance the imaged structures. DHBIM is then combined with spatial compounding to compensate for noise and speckle. The proposed techniques are quantitatively assessed (32 clinical data sets) employing (i) standard image quality measures and (ii) the repeatability of routine clinical measurements, such as chamber diameter and wall thickness. DHBIM introduces a mean increase of 120.9% in tissue/chamber detectability, improving the overall repeatability of clinical measurements by 17%. The integrated approach of DHBIM followed by spatial compounding provides the best overall enhancement of image quality and diagnostic value, consistently outperforming the individual approaches and achieving a 401.4% average increase in tissue/chamber detectability with an associated 24.3% improvement in the overall repeatability of clinical measurements., (Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
18. European Council of Legal Medicine (ECLM) principles for on-site forensic and medico-legal scene and corpse investigation.
- Author
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Cusack D, Ferrara SD, Keller E, Ludes B, Mangin P, Väli M, and Vieira N
- Subjects
- Equipment and Supplies, Europe, Humans, Specimen Handling standards, Forensic Sciences standards
- Abstract
Forensic medical practitioners need to define the general principles governing procedures to be used for the on-site examination of a body where the death has occurred in unnatural, violent or suspicious circumstances. These principles should be followed whenever a medical expert is required to perform an on-site corpse inspection and should be utilised as a set of general guidelines to be adapted to the specific situation in hand and interpreted using common sense and scientific knowledge of the relevant procedures and facts of the case. The aim of these principles is to ensure that forensic evidence at the scene of a death is properly observed and assessed and all necessary relevant evidence gathered in order to ensure that a comprehensive report is available to the judicial authority (investigating judge or coroner) in the justice system. The on-site corpse inspection by a forensic practitioner is a mandatory and essential stage of the forensic and medico-legal autopsy, as it may provide important information for subsequent investigation stages.
- Published
- 2017
- Full Text
- View/download PDF
19. Repatriation of human remains following death in international travellers.
- Author
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Connolly R, Prendiville R, Cusack D, and Flaherty G
- Subjects
- Family psychology, Humans, Body Remains, Cause of Death, Transients and Migrants, Travel, Travel Medicine methods
- Abstract
Background: Death during international travel and the repatriation of human remains to one's home country is a distressing and expensive process. Much organization is required involving close liaison between various agencies., Methods: A review of the literature was conducted using the PubMed database. Search terms included: 'repatriation of remains', 'death', 'abroad', 'tourism', 'travel', 'travellers', 'travelling' and 'repatriation'. Additional articles were obtained from grey literature sources and reference lists., Results: The local national embassy, travel insurance broker and tour operator are important sources of information to facilitate the repatriation of the deceased traveller. Formal identification of the deceased's remains is required and a funeral director must be appointed. Following this, the coroner in the country or jurisdiction receiving the repatriated remains will require a number of documents prior to providing clearance for burial. Costs involved in repatriating remains must be borne by the family of the deceased although travel insurance may help defray some of the costs. If the death is secondary to an infectious disease, cremation at the site of death is preferred. No standardized procedure is in place to deal with the remains of a migrant's body at present and these remains are often not repatriated to their country of origin., Conclusions: Repatriation of human remains is a difficult task which is emotionally challenging for the bereaving family and friends. As a travel medicine practitioner, it is prudent to discuss all eventualities, including the risk of death, during the pre-travel consultation. Awareness of the procedures involved in this process may ease the burden on the grieving family at a difficult time., (© International Society of Travel Medicine, 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com)
- Published
- 2017
- Full Text
- View/download PDF
20. Temporal compounding: a novel implementation and its impact on quality and diagnostic value in echocardiography.
- Author
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Perperidis A, Cusack D, White A, McDicken N, MacGillivray T, and Anderson T
- Subjects
- Algorithms, Humans, Observer Variation, Reproducibility of Results, Signal-To-Noise Ratio, Echocardiography methods, Image Processing, Computer-Assisted methods
- Abstract
Temporal compounding can be used to suppress acoustic noise in transthoracic cardiac ultrasound by spatially averaging partially decorrelated images acquired over consecutive cardiac cycles. However, the reliable spatial and temporal alignment of the corresponding frames in consecutive cardiac cycles is vital for effective implementation of temporal compounding. This study introduces a novel, efficient, accurate and robust technique for the spatiotemporal alignment of consecutive cardiac cycles with variable temporal characteristics. Furthermore, optimal acquisition parameters, such as the number of consecutive cardiac cycles used, are derived. The effect of the proposed implementation of temporal compounding on cardiac ultrasound images is quantitatively assessed (32 clinical data sets providing a representative range of image qualities and diagnostic values) using measures such as tissue signal-to-noise ratio, chamber signal-to-noise ratio, tissue/chamber contrast and detectability index, as well as a range of clinical measurements, such as chamber diameter and wall thickness, performed during routine echocardiographic examinations. Temporal compounding (as implemented) consistently improved the image quality and diagnostic value of the processed images, when compared with the original data by: (i) increasing tissue and cavity signal-to-noise ratios as well as tissue/cavity detectability index, (ii) improving the corresponding clinical measurement repeatability and inter-operator measurement agreement, while (iii) reducing the number of omitted measurements caused by data corruption., (Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.)
- Published
- 2015
- Full Text
- View/download PDF
21. European Council of Legal Medicine (ECLM) accreditation of forensic pathology services in Europe.
- Author
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Mangin P, Bonbled F, Väli M, Luna A, Bajanowski T, Hougen HP, Ludes B, Ferrara D, Cusack D, Keller E, and Vieira N
- Subjects
- Disaster Planning standards, Europe, Forensic Toxicology standards, Humans, Laboratories standards, Photography standards, Quality Control, Research Report standards, Security Measures standards, Societies, Scientific, Specimen Handling standards, Accreditation, Forensic Pathology standards
- Abstract
Forensic experts play a major role in the legal process as they offer professional expert opinion and evidence within the criminal justice system adjudicating on the innocence or alleged guilt of an accused person. In this respect, medico-legal examination is an essential part of the investigation process, determining in a scientific way the cause(s) and manner of unexpected and/or unnatural death or bringing clinical evidence in case of physical, psychological, or sexual abuse in living people. From a legal perspective, these types of investigation must meet international standards, i.e., it should be independent, effective, and prompt. Ideally, the investigations should be conducted by board-certified experts in forensic medicine, endowed with a solid experience in this field, without any hierarchical relationship with the prosecuting authorities and having access to appropriate facilities in order to provide forensic reports of high quality. In this respect, there is a need for any private or public national or international authority including non-governmental organizations seeking experts qualified in forensic medicine to have at disposal a list of specialists working in accordance with high standards of professional performance within forensic pathology services that have been successfully submitted to an official accreditation/certification process using valid and acceptable criteria. To reach this goal, the National Association of Medical Examiners (NAME) has elaborated an accreditation/certification checklist which should be served as decision-making support to assist inspectors appointed to evaluate applicants. In the same spirit than NAME Accreditation Standards, European Council of Legal Medicine (ECLM) board decided to set up an ad hoc working group with the mission to elaborate an accreditation/certification procedure similar to the NAME's one but taking into account the realities of forensic medicine practices in Europe and restricted to post-mortem investigations. This accreditation process applies to services and not to individual practitioners by emphasizing policies and procedures rather than professional performance. In addition, the standards to be complied with should be considered as the minimum standards needed to get the recognition of performing and reliable forensic pathology service.
- Published
- 2015
- Full Text
- View/download PDF
22. Temporal compounding of cardiac ultrasound data: Improving image quality and clinical measurement repeatability.
- Author
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Perperidis A, Cusack D, McDicken N, Macgillivray T, and Anderson T
- Subjects
- Adult, Aged, Aged, 80 and over, Algorithms, Automation, Female, Humans, Male, Middle Aged, Models, Statistical, Reproducibility of Results, Time Factors, Echocardiography methods, Heart physiology, Image Processing, Computer-Assisted methods
- Abstract
Echocardiography provides a powerful and versatile tool for assessing cardiac morphology and function. However, cardiac ultrasound suffers from speckle as well as static and dynamic noise. Over the last three decades, a number of studies have attempted to address the challenging problem of speckle/noise suppression in cardiac ultrasound data. No single method has managed to provide a widely accepted solution. Temporal Compounding is a noise suppression method that utilises spatial averaging of temporally aligned cardiac B-Mode data. Reliable temporal alignment is vital for effective Temporal Compounding. In this study we introduce a novel, accurate and robust technique for the temporal alignment of cardiac cycles with variable temporal characteristics and examine the effect of Temporal Compounding in four clinical measurements performed on routine echocardiographic examinations. Results from 32 patients demonstrate speckle/noise suppression, shadowing reduction, anatomical structure enhancement and improvement in measurement repeatability with no significant or systematic bias introduced. Temporally compound data may be able to provide a good alternative to B-Mode data in clinical measurements as well as a first step to further post-processing of cardiac ultrasound data.
- Published
- 2009
- Full Text
- View/download PDF
23. Stoichiometry of soil enzyme activity at global scale.
- Author
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Sinsabaugh RL, Lauber CL, Weintraub MN, Ahmed B, Allison SD, Crenshaw C, Contosta AR, Cusack D, Frey S, Gallo ME, Gartner TB, Hobbie SE, Holland K, Keeler BL, Powers JS, Stursova M, Takacs-Vesbach C, Waldrop MP, Wallenstein MD, Zak DR, and Zeglin LH
- Subjects
- Climate, Humic Substances analysis, Hydrogen-Ion Concentration, Principal Component Analysis, Regression Analysis, Ecosystem, Enzymes metabolism, Soil analysis
- Abstract
Extracellular enzymes are the proximate agents of organic matter decomposition and measures of these activities can be used as indicators of microbial nutrient demand. We conducted a global-scale meta-analysis of the seven-most widely measured soil enzyme activities, using data from 40 ecosystems. The activities of beta-1,4-glucosidase, cellobiohydrolase, beta-1,4-N-acetylglucosaminidase and phosphatase g(-1) soil increased with organic matter concentration; leucine aminopeptidase, phenol oxidase and peroxidase activities showed no relationship. All activities were significantly related to soil pH. Specific activities, i.e. activity g(-1) soil organic matter, also varied in relation to soil pH for all enzymes. Relationships with mean annual temperature (MAT) and precipitation (MAP) were generally weak. For hydrolases, ratios of specific C, N and P acquisition activities converged on 1 : 1 : 1 but across ecosystems, the ratio of C : P acquisition was inversely related to MAP and MAT while the ratio of C : N acquisition increased with MAP. Oxidative activities were more variable than hydrolytic activities and increased with soil pH. Our analyses indicate that the enzymatic potential for hydrolyzing the labile components of soil organic matter is tied to substrate availability, soil pH and the stoichiometry of microbial nutrient demand. The enzymatic potential for oxidizing the recalcitrant fractions of soil organic material, which is a proximate control on soil organic matter accumulation, is most strongly related to soil pH. These trends provide insight into the biogeochemical processes that create global patterns in ecological stoichiometry and organic matter storage.
- Published
- 2008
- Full Text
- View/download PDF
24. Testing migrant workers for communicable diseases.
- Author
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Cusack D
- Subjects
- Humans, Prejudice, Communicable Diseases diagnosis, Mass Screening methods, Transients and Migrants
- Published
- 2003
25. Family involvement with communication-impaired residents in long-term care settings.
- Author
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Buckwalter KC, Cusack D, Kruckeberg T, and Shoemaker A
- Subjects
- Communication Disorders therapy, Hospitals, Veterans, Humans, Nursing Evaluation Research, Nursing Homes, Speech Therapy standards, Communication Aids for Disabled standards, Communication Disorders nursing, Family psychology, Patient Education as Topic standards
- Abstract
This article describes the outcomes of a study involving family members of communication-impaired long-term care residents in a collaborative nursing/speech language pathology intervention designed to increase the residents' communication ability. Family members provided memorabilia and artifacts or produced audio or video tapes, for use in conjunction with a speech therapy enhancement program (STEP). Findings revealed that, despite a minimal improvement in speech ability, there was a dramatic increase in family members' satisfaction.
- Published
- 1991
- Full Text
- View/download PDF
26. Increasing communication ability in aphasic/dysarthric patients.
- Author
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Buckwalter KC, Cusack D, Sidles E, Wadle K, and Beaver M
- Subjects
- Aged, Aged, 80 and over, Aphasia nursing, Dysarthria nursing, Humans, Skilled Nursing Facilities, Aphasia rehabilitation, Dysarthria rehabilitation, Speech Disorders rehabilitation, Speech Therapy
- Published
- 1989
- Full Text
- View/download PDF
27. Substance P plasma levels in pregnancy and in various clinical disorders.
- Author
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Cusack D, Cannon D, Skrabanek P, and Powell D
- Subjects
- Cystic Fibrosis blood, Female, Humans, Intestinal Diseases blood, Neoplasms blood, Radioimmunoassay, Thyroid Diseases blood, Pregnancy, Substance P blood
- Abstract
Using radioimmunoassay, immunoreactive SP (iSP) has been measured in the plasma of 162 hospital patients with various disorders and in the plasma of 67 pregnant women. In pregnancy, iSP was undetectable in 40% women as compared to 12% in other hospital patients. The mean iSP plasma level in pregnancy was 37.8 +/- 4.6 (SEM) as compared to 77.1 +/- 4.9 (SEM) pg/ml in other hospital patients. The results support earlier observations based on bioassay, suggesting that the blood of pregnant women contains higher concentrations of a SP-inactivating factor. Of the hospital patients, elevated levels of iSP were found in patients with chronic leukaemia, in one patient with a basaloid carcinoma of the anus, and in one patient with toxic liver damage and pancreatic insufficiency. No correlation was found between thyroid function and iSP plasma levels. ISP plasma levels in various gastrointestinal disorders were similar to those found in normal subjects.
- Published
- 1979
- Full Text
- View/download PDF
28. I.g.A. nephropathy in association with Yersinia enterocolitica.
- Author
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Cusack D, Martin P, Schinittger T, McCafferky M, Keane C, and Keogh B
- Subjects
- Adult, Glomerulonephritis immunology, Humans, Male, Yersinia Infections immunology, Yersinia enterocolitica, Glomerulonephritis complications, Immunoglobulin A analysis, Yersinia Infections complications
- Published
- 1983
- Full Text
- View/download PDF
29. The behavioral consequences of a communication intervention on institutionalized residents with aphasia and dysarthria.
- Author
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Buckwalter KC, Cusack D, Beaver M, Sidles E, and Wadle K
- Subjects
- Aged, Combined Modality Therapy, Homes for the Aged, Humans, Language Therapy, Male, Middle Aged, Nursing Homes, Speech Therapy, Aphasia nursing, Behavior Therapy, Dysarthria nursing, Speech Disorders nursing
- Published
- 1988
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