Search

Your search keyword '"D. Descamps"' showing total 667 results
Start Over Author "D. Descamps"
667 results on '"D. Descamps"'

1. Real-time determination of enantiomeric and isomeric content using photoelectron elliptical dichroism

Author

A. Comby, E. Bloch, C. M. M. Bond, D. Descamps, J. Miles, S. Petit, S. Rozen, J. B. Greenwood, V. Blanchet, and Y. Mairesse

Subjects
Science
Abstract

The analysis of chiral chemical mixtures is crucial for many applications. Here, the authors perform real-time analysis of samples by ionizing them with elliptically polarized femtosecond laser pulses and detecting the angular distributions of the photoelectrons.

Published
2018
Full Text
View/download PDF

2. Revealing the Influence of Molecular Chirality on Tunnel-Ionization Dynamics

Author

E. Bloch, S. Larroque, S. Rozen, S. Beaulieu, A. Comby, S. Beauvarlet, D. Descamps, B. Fabre, S. Petit, R. Taïeb, A. J. Uzan, V. Blanchet, N. Dudovich, B. Pons, and Y. Mairesse

Subjects
Physics, QC1-999
Abstract

Light-matter interaction based on strong laser fields enables probing the structure and dynamics of atomic and molecular systems with unprecedented resolutions, through high-order harmonic spectroscopy, laser-induced electron diffraction, and holography. All strong-field processes rely on a primary ionization mechanism where electrons tunnel through the target potential barrier lowered by the laser field. Tunnel ionization is, thus, of paramount importance in strong-field physics and attoscience. However, the tunneling dynamics and properties of the outgoing electronic wave packets often remain hidden beneath the influence of the subsequent scattering of the released electron onto the ionic potential. Here, we present a joint experimental-theoretical endeavor to characterize the influence of sub-barrier dynamics on the amplitude and phase of the wave packets emerging from the tunnel. We use chiral molecules, whose photoionization by circularly polarized light produces forward-backward asymmetric electron distributions with respect to the light propagation direction. These asymmetric patterns provide a background-free signature of the chiral potential in the ionization process. We first implement the attoclock technique, using bicircular two-color fields. We find that, in the tunnel-ionization process, molecular chirality induces a strong forward-backward asymmetry in the electron yield, while the subsequent scattering of the freed electron onto the chiral potential leads to an asymmetric angular streaking of the electron momentum distribution. In order to access the phase of the tunneling wave packets, we introduce subcycle gated chiral interferometry. We employ an orthogonally polarized two-color laser field whose optical chirality is manipulated on a sub-laser-cycle timescale. Numerical simulations are used to interpret the electron interference patterns inherent to this interaction scheme. They show that the combined action of the chiral potential and rotating laser field not only imprints asymmetric ionization amplitudes during the tunneling process, but also induces a forward-backward asymmetric phase profile onto the outgoing electron wave packets. Chiral light-matter interaction thus induces subtle angular-dependent shaping of both the amplitude and the phase of tunneling wave packets.

Published
2021
Full Text
View/download PDF

3. Controlling Subcycle Optical Chirality in the Photoionization of Chiral Molecules

Author

S. Rozen, A. Comby, E. Bloch, S. Beauvarlet, D. Descamps, B. Fabre, S. Petit, V. Blanchet, B. Pons, N. Dudovich, and Y. Mairesse

Subjects
Physics, QC1-999
Abstract

Controlling the polarization state of electromagnetic radiation enables the investigation of fundamental symmetry properties of matter through chiroptical processes. Over the past decades, many strategies have been developed to reveal structural or dynamical information about chiral molecules with high sensitivity, from the microwave to the extreme ultraviolet range. Most schemes employ circularly or elliptically polarized radiation, and more sophisticated configurations involve, for instance, light pulses with time-varying polarization states. All these schemes share a common property—the polarization state of light is always considered as constant over one optical cycle. In this study, we focus on the optical cycle in order to resolve and control a subcyle chiroptical process. We engineer an electric field whose instantaneous chirality can be controlled within the optical cycle, by combining two phase-locked orthogonally polarized fundamental and second harmonic fields. While the composite field has zero net ellipticity, it shows an instantaneous optical chirality which can be controlled via the two-color delay. We theoretically and experimentally investigate the photoionization of chiral molecules with this controlled chiral field. We find that electrons are preferentially ejected forward or backward relative to the laser propagation direction depending on the molecular handedness, similarly to the well-established photoelectron circular dichroism process. However, since the instantaneous chirality switches sign from one half-cycle to the next, electrons ionized from two consecutive half-cycles of the laser show opposite forward-backward asymmetries. This chiral signal, the enantiosensitive subcycle antisymmetric response gated by electric-field rotation, provides a unique insight into the influence of instantaneous chirality in the dynamical photoionization process. More generally, our results demonstrate the important role of subcycle polarization shaping of electric fields as a new route to study and manipulate chiroptical processes.

Published
2019
Full Text
View/download PDF

6. Pharmacokinetic Model of Tenofovir and Emtricitabine and Their Intracellular Metabolites in Patients in the ANRS 134-COPHAR 3 Trial Using Dose Records

Author

Julie Bertrand, Aurélie Barrail-Tran, Lucie Fayette, Rada Savic, Cécile Goujard, Elina Teicher, Caroline Barau, Alain Pruvost, Anne-Marie Taburet, France Mentré, Céline Verstuyft, A. Barrail-Tran, A. Brunet, M.-J. Commoy, S. Couffin-Cadiergues, D. Descamps, X. Duval, C. Goujard, C. Le Guellec, F. Mentré, G. Nembot, A.-M. Taburet, B. Vrijens, •• Ajana, •• Aissi, •• Baclet, •• Besnier, •• Bollens, •• Boulanger, •• Brochier, •• Brunet, •• Chaix, •• Ciuchete, •• Ghosn, •• Duval, •• Ferret, •• Gaubin, •• Goujard, •• Girard, •• Kouadio, •• Lupin, •• Parienti, •• Parrinello, •• Poinçon de la Blanchardière, •• May, •• Marien, •• Medintzeff, •• Metivier, •• Mole, •• Molina, •• Nau, •• Ouazene, •• Pintado, •• Quertainmont, •• Ramani, •• Rami, •• Sellier, •• Simon, •• Talbi, •• Thoirain, •• Verdon, •• Trépo, •• Wassoumbou, •• Yazdanpanah, •• Barrail-Tran, •• Gagneux, •• Delhotal, •• Hoizey, •• Houdret, •• Leguellec, •• Peytavin, •• Poirier, •• Sauvageon, •• Taburet, •• André, •• Soulié, •• Calvez, •• Morand-Joubert, •• Harchi, •• Bocket, •• Mourez, •• Palmer, •• Pallier, •• Deschamps, •• Mazeron, •• Bolmann, •• Storto, •• Thanh Thuy, G. Unal, X. Panhard, and R. Savic

Subjects
Pharmacology, Infectious Diseases, Pharmacology (medical)
Abstract

Tenofovir (TFV) and emtricitabine (FTC) are part of the recommended highly active antiretroviral therapy (ART). Both molecules show a large interindividual pharmacokinetic (PK) variability.

Published
2023
Full Text
View/download PDF

11. First cases of Omicron in France are exhibiting mild symptoms, November 2021-January 2022

Author

A. Maisa, G. Spaccaferri, L. Fournier, J. Schaeffer, J. Deniau, P. Rolland, B. Coignard, A. Andrieu, O. Broustal, S. Chene, S. Chent, E. Fougère, G. Gbaguidi, M. Hamidouche, A. Lamy, Q. Mano, B. Mastrovito, A. Mercier, G. Modenesi, G. Picard, J. Prudhomme, F. Rapilly, A. Riondel, M. Rivière, B. Villegas Ramirez, A. Zhu-Soubise, M. Zurbaran, A. Amzert, L. Andreoletti, A. Bal, R. Beaurepere, S. Behillil, L. Belec, C. Bernard, L. Bocket, L. Bouri, T. Bourlet, C. Bressollette-Bodin, S. Brichler, C. Brugerolles, S. Cado, V. Calvez, N. Capron, S. Castelain, J. Castro-Alvarez, M.-L. Chaix, C. Charpentier, D. Che, C. Chillou, P. Colson, P. Coudene, A. Crinquette, A. De Rougemont, H. Delagrèverie, C. Delamare, T. Denecker-Berardino, D. Descamps, M. Desroches, G. Destras, G. Dos Santos, A. Ducancelle, S. Ducreux, T. Duret, V. Enouf, S. Fafi-Kremer, C. Felici, S. Fourati, P.-E. Fournier, C. Gaudy, H. Germain, V. Giordanengo, O. Gorge, S. Haim-Boukobza, C. Henquell, A. Holstein, L. Houhamdi, J. Izopet, V. Jacomo, A. Jacques, M.-C. Jaffar-Bandjee, M. Jimenez, L. Josset, S. Kemeny, M.-E. Lafon, A. Le Bars, G. Le Corguille, Q. Lepiller, A. Levasseur, N. Leveque, B. Lina, C. Madelaine, C. Malabat, S. Marque-Juillet, T. Martin-Dunavit, P. Mavingui, A. Merens, I. Messak, L. Morand-Joubert, X. Naudot, P. Neybecker, J.-M. Pawlotsky, L. Pilorge, J.-C. Plantier, C. Poggi, M. Pretet, C. Ragot, H. Raoul, S. Rogez, A.-M. Roque-Afonso, B. Roquebert, D. Rousset, F. Rozenberg, C. Sagot, S. Sahnoune, D. Salgado, O. Sand, C. Saudemont, E. Schvoerer, E. Simon-Loriere, R. Stephan, J. Sudour, V. Thibault, E. Tuaillon, A. Vabret, E. Vallee, S. Van Der Werf, J. Van Helden, L. Verdurme, A. Vignola, D. Wilkinson, Y. Yazdanpanah, Santé publique France - French National Public Health Agency [Saint-Maurice, France], EMERGEN consortium, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), NASA Ames Research Center (ARC), Service d'Hépato-Gastro-Entérologie et Nutrition [CHU Limoges], CHU Limoges, Département lmage et Traitement Information (IMT Atlantique - ITI), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Equipe DECIDE (Lab-STICC_DECIDE), Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (Lab-STICC), École Nationale d'Ingénieurs de Brest (ENIB)-Université de Bretagne Sud (UBS)-Université de Brest (UBO)-École Nationale Supérieure de Techniques Avancées Bretagne (ENSTA Bretagne)-Institut Mines-Télécom [Paris] (IMT)-Centre National de la Recherche Scientifique (CNRS)-Université Bretagne Loire (UBL)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-École Nationale d'Ingénieurs de Brest (ENIB)-Université de Bretagne Sud (UBS)-Université de Brest (UBO)-École Nationale Supérieure de Techniques Avancées Bretagne (ENSTA Bretagne)-Institut Mines-Télécom [Paris] (IMT)-Centre National de la Recherche Scientifique (CNRS)-Université Bretagne Loire (UBL)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT), Institut des Géosciences de l’Environnement (IGE), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP), Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Santé publique France, the French national public health agency.Caisse nationale d’assurance maladie (Cnam), the national health insurance funds.'Enhancing Whole Genome Sequencing (WGS) and/or Reverse Transcription Polymerase Chain Reaction (RT-PCR) national infrastructures and capacities to respond to the COVID-19 pandemic in the European Union and European Economic Area' Grant Agreement ECDC/HERA/2021/007 ECD. 12221., Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées (IRBA), and COMBE, Isabelle

Subjects
Adult, Epidemiology, MESH: Hospitalization, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: COVID-19, Humans, MESH: SARS-CoV-2, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Signs and symptoms, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, MESH: Humans, SARS-CoV-2, Vaccination, COVID-19, MESH: Adult, MESH: Vaccination, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, MESH: France, Hospitalization, Infectious Diseases, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, France, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Surveys and questionnaires, [SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology
Abstract

International audience; ObjectivesWe aimed to investigate the first Omicron cases detected in France in order to assess case characteristics and provide supporting information on the possible impact of this variant on the healthcare system.MethodsA standardized questionnaire was used to collect information from confirmed and probable Omicron cases.ResultsMedian age of 468 investigated cases was 35 years, 376 were symptomatic (89%); 64% were vaccinated with two doses and 7% had received three doses. Loss of smell and taste were reported by 8.3% and 9% of cases, respectively. Seven cases were hospitalized, three of those were unvaccinated (including two with reported precondition). No admissions to intensive care and no deaths were reported.ConclusionsOur results confirm a mild clinical presentation among the first Omicron cases detected in France and highlight the importance for the national COVID-19 surveillance system to quickly detect and adapt to the emergence of a new variant.

Published
2022
Full Text
View/download PDF

12. [Pulmonary mucosa during the perinatal period: Can understanding of the lung help to combat the infant's sensitivity to bronchiolitis?]

Author

C, Chottin, Q, Marquant, V, Saint-Criq, M, Thomas, S, Riffault, and D, Descamps

Subjects
Mucous Membrane, Adolescent, Respiratory Syncytial Virus, Human, Bronchiolitis, Humans, Infant, Respiratory Syncytial Virus Infections, Lung
Abstract

Due to infection with the respiratory syncytial virus (RSV), bronchiolitis is the main respiratory disease in infants, and no effective treatments currently exist. The perinatal period is an important stage in the maturation of the lung mucosa, insofar as it largely determines the host's pulmonary reactivity to pathogens. Understanding the physiological, immunological and microbiological characteristics of the lungs in early life may lead to new innovative strategies against infectious agents. We hypothesize that the lung microbiota represents a regulatory factor of paramount importance in young people's health.

Published
2022

14. 50W Yb:YAG Thin-Disk Picosecond Regenerative Amplifier Operating At 1 KHz

Author

M.-C. Nadeau, P. Balcou, D. Descamps, C. Féral, V. Fortin, J. Lhermite, D. Marion, E. Mével, A. Rohm, and S. Petit

Abstract

We report the development of a 1 kHz-900-fs Yb:YAG thin-disk regenerative amplifier delivering 50 mJ. We discuss how to address thermal issues in Pockels cell to further increase the output energy up to 100 mJ.

Published
2022
Full Text
View/download PDF

17. Role of Spin-Orbit Coupling in High-order Harmonic Generation Revealed by Super-Cycle Rydberg Trajectories

Author

N. Mayer, S. Beaulieu, Á. Jiménez-Galán, S. Patchkovskii, O. Kornilov, D. Descamps, S. Petit, O. Smirnova, Y. Mairesse, and M. Y. Ivanov

Subjects
Atomic Physics (physics.atom-ph), General Physics and Astronomy, FOS: Physical sciences, Physics - Atomic Physics, Physics - Optics, Optics (physics.optics)
Abstract

High-harmonic generation is typically thought of as a sub-laser-cycle process, with the electron's excursion in the continuum lasting a fraction of the optical cycle. However, it was recently suggested that long-lived Rydberg states can play a particularly important role in atoms driven by the combination of the counter-rotating circularly polarized fundamental light field and its second harmonic. Here we report direct experimental evidence of long and stable Rydberg trajectories contributing to high-harmonic generation. We confirm their effect on the harmonic emission via Time-Dependent Schr{\"o}dinger Equation simulations and track their dynamics inside the laser pulse using the spin-orbit evolution in the ionic core, utilizing the spin-orbit Larmor clock. Our observations contrast sharply with the general view that long-lived Rydberg orbits should generate negligible contribution to the macroscopic far-field high harmonic response of the medium. Indeed, we show how and why radiation from such states can lead to well collimated macroscopic signal in the far field.

Published
2021
Full Text
View/download PDF

18. Optics-free focusing and application to spectral filtering of XUV beam

Author

F. Catoire, C. Péjot, E. Constant, Eric Mével, Frédéric Burgy, C. Valentin, J. Vabék, K. Veyrinas, D. Descamps, Centre d'Etudes Lasers Intenses et Applications (CELIA), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), ELI Beamlines, Czech Technical University in Prague (CTU), Structure et dynamique multi-échelle des édifices moléculaires (DYNAMO), Institut Lumière Matière [Villeurbanne] (ILM), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institute of Physics of the Czech Academy of Sciences (FZU / CAS), Czech Academy of Sciences [Prague] (CAS)-Czech Academy of Sciences [Prague] (CAS), and OSA

Subjects
Physics, [PHYS]Physics [physics], [PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics], 0303 health sciences, business.industry, Spectral filtering, Physics::Optics, 01 natural sciences, 03 medical and health sciences, [SPI]Engineering Sciences [physics], Optics, Physics::Plasma Physics, Extreme ultraviolet, 0103 physical sciences, Physics::Atomic and Molecular Clusters, [CHIM]Chemical Sciences, ISBN: 978-1-943580-83-5, 010306 general physics, business, Beam (structure), 030304 developmental biology
Abstract

Poster session III (Tu4A); International audience; We experimentally characterize XUV intensity profiles and wavefronts, and demonstrate XUV beams focusing without resorting any optics. We use this coherent effect to spectrally filter group of harmonics. Simulations show possible control of attosecond temporal structure.

Published
2020
Full Text
View/download PDF

20. Universality of photoelectron circular dichroism in the photoionization of chiral molecules

Author

S Beaulieu, A Ferré, R Géneaux, R Canonge, D Descamps, B Fabre, N Fedorov, F Légaré, S Petit, T Ruchon, V Blanchet, Y Mairesse, and B Pons

Subjects
photoelectron circular dichroism, chirality, strong fields, multiphoton ionization, 33.55.+b, 78.20.Ek, Science, Physics, QC1-999
Abstract

Photoionization of chiral molecules by circularly polarized radiation gives rise to a strong forward/backward asymmetry in the photoelectron angular distribution, referred to as photoelectron circular dichroism (PECD). Here we show that PECD is a universal effect that reveals the inherent chirality of the target in all ionization regimes: single photon, multiphoton, above-threshold and tunnel ionization. These different regimes provide complementary spectroscopic information at electronic and vibrational levels. The universality of the PECD can be understood in terms of a classical picture of the ionizing process, in which electron scattering on the chiral potential under the influence of a circularly polarized electric field results in a strong forward/backward asymmetry.

Published
2016
Full Text
View/download PDF

21. Caractéristiques cliniques et pronostiques des bactériémies à Staphylococcus aureus dans un centre hospitalier général

Author

O. Oddoux, S. Nguyen, D. Descamps, and P. Wallard

Subjects
Infectious Diseases
Abstract

Introduction Cette etude a pour but d’evaluer prospectivement les caracteristiques et le pronostic des bacteriemies a S. aureus (SA) dans un CH general. Materiels et methodes Dans notre centre, les bacteriemies sont suivies de maniere prospective par un infectiologue, avec intervention sur la prise en charge si necessaire, recueil de donnees cliniques, microbiologiques, et d’antibiotherapie (ATB). Ces donnees sont inserees dans une base de donnees anonymisee (logiciel Epidata). Une extraction a ete realisee sur les bacteriemies a SA pour la periode du 01/05/17 au 31/12/2019. Resultats Durant la periode d’etude, 219 episodes de bacteriemies a SA etaient identifies (16 % des 1395 episodes bacteriemiques). L’âge moyen etait de 68 ± 17 ans, avec 56 % d’hommes, et un taux d’immunodepression de 66 % (144/219, principalement diabete [n = 80], neoplasie [n = 47], immunosuppresseur [n = 42]). Le taux d’infections associees aux soins etait de 49 %, et les portes d’entrees principales etaient : dispositif vasculaire (n = 49, 23 %), inconnues (n = 41, 19 %) et cutanees (n = 34, 16 %). Une endocardite etait identifiee dans 8 % cas (n = 17). Le taux de resistance a la methicilline des SA etait de 15 %. Des hemocultures de controle etaient realisees a j2–j4 dans 156/167 cas (93 %), et une echographie cardiaque dans 152/167 cas (92 %). La PCR pour identification de la resistance a la methicilline etait realisee dans 132 cas (60 %). Le taux de sepsis grave/choc septique etait de 45 % (99/219). L’ATB probabiliste etait instauree dans 71 % cas (155/219), avec une antibiotherapie efficace dans 135/155 episodes (87 %). Le delai median d’ATB adaptee a la bacteriemie a SA etait de 1 j ± 1,3 j. Le taux de deces a j7 etait de 31/219 (14 %), similaire au taux de deces pour les bacteriemies a autres germes (122/1176 [10 %], p = 0,1). Le taux de deces a j30 etait de 48/219 (22 %), tendant a etre plus eleve que les bacteriemies a autre germe (194/1176 [16 %], p = 0,052). L’âge, les CMI de la vancomycine, le taux de resistance a la methicilline, et l’efficacite de l’ATB probabiliste n’etaient pas associes au deces a j7, alors que les CMI de la teicoplanine tendaient a etre plus elevees chez les patients decedes a j7 (0,62 ± 0,46 mg/L vs 0,45 ± 0,22 mg/L chez les survivants, p = 0,052). Une CMI de teicoplanine Conclusion Dans notre centre, les bacteriemies a SA sont frequemment associees a une immunosuppression et aux infections associees aux soins. La mortalite precoce a j7 etait plus basse en cas d’utilisation de la PCR pour detection de la resistance a la methicilline, et pour les souches de SA avec une CMI a la teicoplanine

Published
2020
Full Text
View/download PDF

22. In vitro susceptibility to mecillinam of Escherichia coli strains isolated from the urine of pregnant women

Author

Claire Duployez, C. Cattoen, Caroline Loïez, D. Descamps, A. Vachée, and Frédéric Wallet

Subjects
Adult, 0301 basic medicine, Bacteriuria, Urinary system, 030106 microbiology, Urine, Biology, medicine.disease_cause, beta-Lactamases, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Disk Diffusion Antimicrobial Tests, Pregnancy, medicine, Humans, Uropathogenic Escherichia coli, Prodrugs, Acute Cystitis, Prospective Studies, Agar diffusion test, Pregnancy Complications, Infectious, Mecillinam, Escherichia coli, Escherichia coli Infections, digestive, oral, and skin physiology, Amdinocillin, Amdinocillin Pivoxil, Drug Resistance, Microbial, medicine.disease, Anti-Bacterial Agents, Pivmecillinam, Infectious Diseases, chemistry, Asymptomatic Diseases, Urinary Tract Infections, Female, medicine.drug
Abstract

Objectives Pivmecillinam is a safe beta-lactam for use in pregnancy. It has been widely used for the treatment of lower urinary tract infections (UTIs) in the Nordic countries where its efficacy, minor impact on the microbiota, and low level of resistance among the Escherichia coli strains have been proven. However, susceptibility data related to E . coli involved in asymptomatic bacteriuria and lower UTIs in pregnant women is lacking. We aimed to support the 2015 recommendations issued by the French Infectious Diseases Society (SPILF) on gestational UTI, with a particular focus on pivmecillinam. Material and methods Antimicrobial susceptibility testing was performed by 12 hospitals with a maternity department on 235 E . coli strains isolated from the urine of pregnant women. Susceptibility to mecillinam was tested by disk diffusion method using the 2015 recommendations of the antibiogram committee of the French microbiology society (CA-SFM). Results Global susceptibility to mecillinam was 86.4%. Susceptibility to mecillinam was 96.5% for strains susceptible to amoxicillin-clavulanic acid and 38.7% for resistant strains. All six extended-spectrum beta-lactamase-producing E . coli strains were susceptible to mecillinam. Conclusion Given the efficacy and safety of pivmecillinam during pregnancy, it may be used for the documented treatment of asymptomatic bacteriuria and acute cystitis in pregnant women. It also represents an alternative for the treatment of multidrug-resistant bacterial infections.

Published
2016
Full Text
View/download PDF

23. Prise en charge de l’ostéite du pied diabétique par chirurgie conservatrice

Author

O. Robineau, D. Descamps, Eric Senneville, S. Nguyen, and P. Wallard

Subjects
Infectious Diseases
Abstract

Introduction L’osteite du pied chez le patient diabetique (OPD) est une complication grave associee a un risque eleve d’amputation. Deux types de prises en charge de l’OPD sont rapportes : l’approche medicale (sans resection osseuse) et l’approche medicochirurgicale qui est parfois une chirurgie conservatrice (CS) assez peu etudiee et qui correspond a une resection limitee a la zone infectee associee a une antibiotherapie (ATB) guidee par biopsie osseuse. Materiels et methodes Etude retrospective des episodes d’OPD traites par CS completee par une ATB adaptee a la biopsie osseuse, dans deux centres hospitaliers entre juin 2007 et decembre 2017. Au terme d’un suivi d’un an, la remission etait definie par l’absence de dermohypodermite, une cicatrisation complete de la plaie maintenue au moins un mois, une stabilisation ou amelioration des images osteoarticulaires et l’absence de reprise chirurgicale. Resultats Durant la periode d’analyse, 47 episodes chez 41 patients ont ete identifies. La moyenne d’âge des patients etait de 69,4 ± 8,9 ans, l’HBA1 C etait en moyenne de 7,2 ± 1,1 %. Un antecedent d’amputation etait trouve dans 43 % des cas (n = 20), et dans 32 % des episodes (n = 15) les patients etaient porteurs d’une stenose arterielle. Staphylococcus spp. etaient predominants (40 %, 50/124 souches), et 72 % des episodes etaient polymicrobiens (n = 34). En excluant les 3 deces tous non relies a l’episode infectieux et les perdus de vue avant 1 an (n = 5), le taux de remission infectieuse a 1 an etait de 64 % (25/39). Les echecs survenaient precocement dans les 6 mois du suivi (11/14, soit 79 %). Les patients en echec de traitement etaient plus frequemment porteurs d’une stenose arterielle du membre inferieur homolateral a l’osteite que les patients en remission : 57 % (8/14) versus 24 % (6/25) respectivement (p = 0,04). Le taux de CRP initial chez les patients en echec a un an etait significativement plus eleve (116 ± 112 mg/L) que celui des patients en remission (48 ± 46 mg/L) (p = 0,02). Il existait une tendance a avoir plus d’abces dans le groupe echec que dans le groupe remission : 29 % (4/14) versus 4 % (1/23) (p = 0,06). Les durees et type d’ATB (rifampicine sur Staphylococcus spp. et fluoroquinolones sur les bacilles Gram negatif) etaient similaires dans les deux groupes. Au suivi a un an, des lesions de transfert par modification de la statique du pied etaient retrouvees chez 26 % des patients. Parmi les patients en remission a 1 an, 92 % (23/25) restaient en remission au cours du suivi ulterieur, avec un suivi moyen de 2,9 ± 1,7 ans. La cicatrisation de l’ulcere etait obtenue pour 31/47 patients (66 %), et durable pour 28 patients au dernier suivi (moyenne 2,1 ± 1,7 ans). Conclusion La CS est associee a un taux de remission de l’infection comparable a ce qui a deja ete rapporte dans la litterature malgre le profil moins favorable de nos patients (antecedent d’amputation, abces, arterite). L’evaluation des OPD a un an post-traitement semble suffisante. La prise en charge vasculaire est essentielle.

Published
2020
Full Text
View/download PDF

24. Analyse des bactériémies chez les patients cirrhotiques dans un centre hospitalier général

Author

C. Baillie, D. Descamps, O. Oddoux, S. Nguyen, A. Hilmoine, and M. Anastay

Subjects
Infectious Diseases
Abstract

Introduction Il existe peu de donnees dans la litterature sur les bacteriemies survenant chez les patients cirrhotiques. Notre but etait d’evaluer les bacteriemies de cette population dans notre etablissement sur une periode consecutive de 8 mois. Materiels et methodes Analyse realisee a partir d’une base de donnees anonymisee (logiciel Epidata), recueillant de maniere prospective des donnees cliniques, microbiologiques et d’antibiotherapie empirique (ATB) pour les bacteriemies significatives survenues entre le 01/05/17 et le 31/12/2017 dans un centre hospitalier general (CHG). Resultats Pendant la periode d’etude, 30/346 (8,7 %) episodes bacteriemiques sont survenus chez des patients cirrhotiques. Les patients cirrhotiques etaient significativement plus jeunes que les non-cirrhotiques (67,7 ans vs 71,6 ans ; p Le taux d’instauration de l’ATB probabiliste etait similaire entre patients cirrhotiques et non cirrhotiques (76,7 % [23/30] vs 79,4 % [251/316] ; p = 0,72), de meme que l’efficacite de l’ATB instauree (87 % [20/23] vs 84,5 % [212/251] ; p = 1). On notait un taux de sepsis grave/choc septique plus eleve en cas de cirrhose compare au patients non cirrhotiques (60 % [18/30] vs 30,9 % [126/316] ; p = 0,03) et un taux de mortalite plus eleve a j30 (36,7 % [11/30] vs 15,9 % [50/316] ; p = 0,004), la mortalite tendant a etre plus elevee a j7 (20 % [6/30] vs 10,1 % [32/316] ; p = 0,12). Conclusion Dans notre etablissement, les bacteriemies des patients cirrhotiques concernent des sujets plus jeunes et plus frequemment instables que les patients non cirrhotiques. Le taux de mortalite etait significativement plus eleve en cas de cirrhose, malgre un taux d’instauration et d’efficacite de l’ATB probabiliste similaire aux patients non cirrhotiques. Sur le plan microbiologique, les taux de SARM et d’enterobacteries resistantes aux C3G n’etaient pas significativement plus eleves en cas de cirrhose.

Published
2018
Full Text
View/download PDF

25. Tentative d’autolyse compliquée d’une pneumopathie d’inhalation révélant… une légionellose. Apport de l’antigène légionelle urinaire dans le diagnostic

Author

D. Descamps, A. Skalli, D. Trivier, E. Beclin, S. Nguyen, A. Ratsimbazafy, and S. Dekeyser

Subjects
medicine.medical_specialty, Suicide attempt, business.industry, Urinary system, Biochemistry (medical), Clinical Biochemistry, Aspiration pneumonia, medicine.disease, Delayed diagnosis, Gastroenterology, New diagnosis, Clavulanic acid, Internal medicine, medicine, Pancreatitis, Acute pneumonia, Intensive care medicine, business, medicine.drug
Abstract

Summary We present an atypical case of legionellosis, with delayed diagnosis. A woman was hospitalised for suicide attempt complicated by aspiration pneumonia, and secondarily by acute renal failure and pancreatitis. Diagnosis of legionellosis was made lately, thanks to urinary antigen test. This case figures out the difficulty of diagnosing this infection in case of neuropsychiatric disorders, and the usefulness of new diagnosis tools. Partial improvement of the patient under treatment with amoxicillin-clavulanic acid may be explained by bactericidal activity of clavulanic acid on the bacteria, described on cellular and in murine models of acute pneumonia.

Published
2012
Full Text
View/download PDF

26. Outcome of patients with diabetes with negative percutaneous bone biopsy performed for suspicion of osteomyelitis of the foot

Author

E. Beltrand, D. Descamps, L. Legout, J. P. Canonne, M. Caillaux, D. Gaworowska, E. Senneville, H. Topolinski, B. Singer, Yazdan Yazdanpanah, S. Nguyen, and F. Devemy

Subjects
medicine.medical_specialty, Percutaneous, medicine.diagnostic_test, business.industry, Endocrinology, Diabetes and Metabolism, Osteomyelitis, Radiography, Retrospective cohort study, medicine.disease, Surgery, Endocrinology, Diabetes mellitus, Biopsy, Internal Medicine, medicine, Radiology, business, Foot (unit), Bone biopsy
Abstract

Diabet. Med. 29, 56–61 (2012) Abstract Aims To assess the outcome of patients with diabetes with suspicion of osteomyelitis of the foot who had undergone a percutaneous bone biopsy that yielded negative microbiological results, with focus on the occurrence of osteomyelitis at the biopsied site. Methods Medical charts of adult patients with diabetes with a negative percutaneous bone biopsy were reviewed. Patients’ outcome was evaluated at least 2 years after the initial bone biopsy according to wound healing, the results of a new bone biopsy and bone imaging evaluation when applicable. Results From January 2001 to January 2008, 41 patients with diabetes (30 men/11 women; mean age 58.1 ± 9.6 years; mean diabetes duration 15.8 ± 6.7 years) met study criteria. Osteomyelitis was suspected based on combined clinical and imaging diagnostic criteria. On follow-up at a mean duration of 41.2 ± 22.5 months post-bone biopsy, 16 patients had complete wound healing (39.0%). Of the 25 other patients, 15 had a new bone biopsy performed, six of which yielded positive microbiological results, and among the 10 patients who neither healed nor underwent bone biopsy, comparative radiography of the foot showed a stable aspect of the biopsied site in six of them, for whom the data were available. Finally, osteomyelitis of the foot at the site where the initial bone biopsy had been performed was confirmed during follow-up in six patients (14.6%) and was suspected in four additional patients (9.7%). Conclusions The results of the present study suggest that, of patients with diabetes with the suspicion of osteomylelitis and a negative percutaneous bone biopsy, only one out of four will develop osteomyelitis within 2 years of the biopsy.

Published
2011
Full Text
View/download PDF

27. Bactériémies et Programme de médicalisation des systèmes d’information : valorisation financière de l’infectiologue à l’hôpital

Author

D. Descamps, S. Dekeyser, S. Nguyen, and F. Dufossez

Subjects
Infectious Diseases, Medical staff, Political science, Humanities, Cost savings
Abstract

Resume Objectif La surveillance des bacteriemies est une des missions du referent en antibiotherapie. Nous proposons une approche originale de valorisation financiere de cette surveillance, grâce a la correction des codages du Programme de medicalisation des systemes d’information (PMSI) a partir d’une base de donnees recensant les bacteriemies. Methode Une base de donnees recensant les bacteriemies communautaires et associees aux soins a ete mise en place au CH Bethune depuis le 1er janvier 2009 a l’aide du logiciel EPI-Info (EPI Data). Lorsqu’elles etaient manquantes, les donnees de bacteriemies, leur caractere communautaire/associe aux soins et leur porte d’entree ont ete inseres par le departement d’information medicale dans les codages PMSI des patients pris en charge en MCO (410 lits) en 2009. Le gain financier etait evalue par la difference de recettes T2A avant et apres correction des codages. Resultat En 2009, parmi les 35 000 patients hospitalises en MCO, 383 ont presente un episode bacteriemique. Apres ajout des codes manquants, 64 dossiers ont finalement ete revalorises financierement en T2A, avec un gain de 229 291 euros. Conclusion Ce travail de surveillance des bacteriemies, transversal et centre sur la qualite des soins, se traduit par un gain T2A mesurable. Cette approche est interessante car tout medecin exercant en transversal eprouve des difficultes a valoriser son activite dans le systeme T2A actuel, en particulier sans activite d’hospitalisation. Notre travail traduit aussi la difficulte des praticiens a coder toutes les pathologies, ce qui peut etre responsable d’une perte financiere dans le systeme T2A.

Published
2011
Full Text
View/download PDF

28. Intérêt de la mise en place de la recherche des gènes vanA et vanB par technique PCR en système clos (Xpert vanA/vanB Cepheid®) dans un laboratoire de microbiologie dans le cadre de la gestion d’une épidémie à Enterococcus faecium résistant aux glycopeptides (EfRG)

Author

E. Beclin, S. Dekeyser, and D. Descamps

Subjects
Enterocoque, General Medicine, Biology, Molecular biology
Abstract

Resume Objet Face aux difficultes rencontrees lors de la gestion de deux epidemies a ERG, le laboratoire a etudie l’interet de rechercher les genes vanA et vanB par PCR temps reel en systeme clos (Xpert vanA/vanB Cepheid ® ) pour ameliorer le delai de reponse, la prise en charge des patients et le controle de la transmission croisee. Methode De mars a decembre 2009, 565 prelevements ont ete analyses par PCR, associe a un ensemencement systematique pendant deux mois de 75 echantillons puis culture uniquement des echantillons positifs en PCR pour les genes vanA et/ou vanB . Resultats La sensibilite et la valeur predictive negative de la PCR etaient de 100 %. La specificite a ete evaluee en contexte et hors contexte epidemique : 69,3 et 76,8 % respectivement. Les variations interservices du taux de faux-positif en phase non epidemique sont moins importantes qu’en phase epidemique. Le taux global de faux-positif de 23,9 %. Conclusion Cette technologie est d’integration facile en routine : resultats en une heure pour quatre echantillons testes versus 72 heures pour la culture. Malgre son cout reactif, elle represente un outil diagnostique important a l’echelle d’un etablissement : amelioration de la gestion des lits des zones de regroupement, transferts facilites, adaptation des mesures d’hygiene et de la prise en charge therapeutique des patients. La culture reste cependant indispensable pour confirmer tout resultat positif obtenu en PCR et suivre epidemiologiquement la sensibilite des souches.

Published
2011
Full Text
View/download PDF

31. Épidémie à Enterococcus faecium résistant à la vancomycine de type Van B au centre hospitalier de Béthune (Pas-de-Calais). Réalisation de deux enquêtes de prévalence en mai 2008 et en janvier 2009

Author

D. Descamps, E. Beclin, S. Nguyen, F. Dufossez, and S. Dekeyser

Subjects
Gynecology, Point prevalence survey, medicine.medical_specialty, Medical treatment, business.industry, Vancomycin resistant, medicine, General Medicine, Outbreak control, business
Abstract

Resume But de l’etude Dans le cadre de la maitrise de l’epidemie a Enterococcus faecium ( E. faecium ) resistant a la vancomycine (EfRV) de type Van B qui sevit au centre hospitalier de Bethune depuis mars 2008 (deux vagues successives), deux enquetes de prevalence ont ete organisees en mai 2008 et en janvier 2009, dans les services non encore touches pour tous les patients hospitalises depuis au moins 24 heures dans l’etablissement. Patients et methode Dans chaque service, information au patient, recueil des donnees administratives et therapeutiques necessaires a l’enquete : realisation des prelevements (ecouvillonnage intrarectal profond ou selle), mise en culture sur milieu selectif chromogene, saisie et exploitation des resultats avec le logiciel Epidata apres verification et anonymisation des fiches. Resultats En mai 2008, sur les 239 patients preleves le jour de l’enquete, neuf se sont reveles porteurs (taux de prevalence : 3,76 %) avec identification de trois nouveaux services : neurologie, chirurgie viscerale et soins continus d’urgence. En janvier 2009, 157 patients ont ete depistes : seul un patient hospitalise en soins intensifs cardiologiques s’est revele porteur d’EfRV (taux de prevalence 0,63%). Conclusion Le but de ces deux enquetes etait de mieux controler les deux vagues epidemiques en etablissant un etat des lieux du portage ERV au centre hospitalier de Bethune. Les patients colonises nouvellement identifies ont ete rapidement pris en charge en zone de cohorting . Cinq cas secondaires ont ete identifies parmi les 181 contacts generes en mai 2008 et aucun cas secondaire (32 contacts) en janvier 2009.

Published
2010
Full Text
View/download PDF

32. Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women

Author

J, Paavonen, P, Naud, J, Salmerón, C M, Wheeler, S-N, Chow, D, Apter, H, Kitchener, X, Castellsague, J C, Teixeira, S R, Skinner, J, Hedrick, U, Jaisamrarn, G, Limson, S, Garland, A, Szarewski, B, Romanowski, F Y, Aoki, T F, Schwarz, W A J, Poppe, F X, Bosch, D, Jenkins, K, Hardt, T, Zahaf, D, Descamps, F, Struyf, M, Lehtinen, G, Dubin, and J-L, Maroye

Subjects
Adult, Oncology, medicine.medical_specialty, Adolescent, Sexual Behavior, Uterine Cervical Neoplasms, HPV vaccines, Cervical intraepithelial neoplasia, Mass Vaccination, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Internal medicine, medicine, Humans, Papillomavirus Vaccines, 030212 general & internal medicine, Neoplasm Staging, Vaginal Smears, Cervical cancer, Human papillomavirus 16, Human papillomavirus 18, business.industry, Gardasil, Papillomavirus Infections, HPV infection, General Medicine, Uterine Cervical Dysplasia, medicine.disease, Vaccine efficacy, female genital diseases and pregnancy complications, 3. Good health, Vaccination, Treatment Outcome, 030220 oncology & carcinogenesis, Immunology, Female, Cervarix, Safety, business, Precancerous Conditions, medicine.drug
Abstract

Summary Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections, and associated precancerous lesions in an event-triggered interim analysis of the phase III randomised, double-blind, controlled PApilloma TRIal against Cancer In young Adults (PATRICIA). We now assess the vaccine efficacy in the final event-driven analysis. Methods Women (15–25 years) were vaccinated at months 0, 1, and 6. Analyses were done in the according-to-protocol cohort for efficacy (ATP-E; vaccine, n=8093; control, n=8069), total vaccinated cohort (TVC, included all women receiving at least one vaccine dose, regardless of their baseline HPV status; represents the general population, including those who are sexually active; vaccine, n=9319; control, n=9325), and TVC-naive (no evidence of oncogenic HPV infection at baseline; represents women before sexual debut; vaccine, n=5822; control, n=5819). The primary endpoint was to assess vaccine efficacy against cervical intraepithelial neoplasia 2+ (CIN2+) that was associated with HPV-16 or HPV-18 in women who were seronegative at baseline, and DNA negative at baseline and month 6 for the corresponding type (ATP-E). This trial is registered with ClinicalTrials.gov, number NCT00122681. Findings Mean follow-up was 34·9 months (SD 6·4) after the third dose. Vaccine efficacy against CIN2+ associated with HPV-16/18 was 92·9% (96·1% CI 79·9–98·3) in the primary analysis and 98·1% (88·4–100) in an analysis in which probable causality to HPV type was assigned in lesions infected with multiple oncogenic types (ATP-E cohort). Vaccine efficacy against CIN2+ irrespective of HPV DNA in lesions was 30·4% (16·4–42·1) in the TVC and 70·2% (54·7–80·9) in the TVC-naive. Corresponding values against CIN3+ were 33·4% (9·1–51·5) in the TVC and 87·0% (54·9–97·7) in the TVC-naive. Vaccine efficacy against CIN2+ associated with 12 non-vaccine oncogenic types was 54·0% (34·0–68·4; ATP-E). Individual cross-protection against CIN2+ associated with HPV-31, HPV-33, and HPV-45 was seen in the TVC. Interpretation The HPV-16/18 AS04-adjuvanted vaccine showed high efficacy against CIN2+ associated with HPV-16/18 and non-vaccine oncogenic HPV types and substantial overall effect in cohorts that are relevant to universal mass vaccination and catch-up programmes. Funding GlaxoSmithKline Biologicals.

Published
2009
Full Text
View/download PDF

33. National survey of the prevalence and conditions of selection of HIV-1 reverse transcriptase K70E mutation

Author

C, Delaugerre, P, Flandre, A G, Marcelin, D, Descamps, C, Tamalet, J, Cottalorda, V, Schneider, S, Yerly, J, LeGoff, L, Morand-Joubert, M L, Chaix, D, Costagliola, and V, Calvez

Subjects
Combination therapy, Anti-HIV Agents, Mutation, Missense, HIV Infections, Drug resistance, Virology, Drug Resistance, Viral, Humans, Selection, Genetic, Sida, Retrospective Studies, biology, virus diseases, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, HIV Reverse Transcriptase, Reverse transcriptase, Regimen, Infectious Diseases, Amino Acid Substitution, Concomitant, Lentivirus, Mutation (genetic algorithm), HIV-1, France
Abstract

Tenofovir disoproxil fumarate (TDF) has become an important component of HIV combination therapy because of its potency and once-daily dosing. Key mutation associated with resistance to TDF is a K65R in the reverse transcriptase (RT) gene. According to occurrence of K70E mutation after failure to TDF regimen, this mutation was recently reported as a mutation associated with TDF resistance in most resistance genotypic algorithms. The aim of this study was to analyze, retrospectively, the prevalence and conditions of selection of HIV-1 RT K70E mutation from a national clinical survey. Absence of selection of K70E in 850 HIV-1-infected naive patients suggests its role in NRTI drug resistance. Prevalence of K70E RT was low (99/41601, 0.24%) in patients treated between 1999 and 2005. Conversely with K65R mutation, thymidine analog mutations (TAMs) can be concomitantly observed with K70E mutation but its frequency decreased as the number of TAM increases. Concomitant association of K65R and K70E was possible but infrequent (11%). At the time of K70E selection, 60% of patients had received or received TDF-containing regimen and one-third received exclusive NRTI regimen. In conclusion, the K70E mutation could be an alternative pathway of TDF resistance, but as the K65R mutation, other NRTI as ABC, ddI, and 3TC could be also associated with the K70E selection.

Published
2008
Full Text
View/download PDF

34. Prévalence de la résistance d’Escherichia coli isolés de prélèvements urinaires (U) ou gastro-intestinaux (D) à l’association ticarcilline-acide clavulanique et aux autres antibiotiques

Author

C. Cattoen, M. Vasseur, M. Menouar, M. Roussel-Delvallez, D. Descamps, S. Samaille, A. Decoster, M.N. Noulard, A. Vachée, M. Caillaux, A. Verhaeghe, J.G. Paul, C. Rolland, F. Wallet, N. Gravelines, L. Lecci, R.J. Courcol, M.P. Pelletier, S. Hendricx, and A. Charlet

Subjects
Infectious Diseases, Pharmacology (medical)
Abstract

Resume Objectif Cette etude evalue la prevalence de la sensibilite a l’association ticarcilline-acide clavulanique (TCC) d’ E. coli et analyse les resultats en fonction des methodes d’antibiogramme utilisees. Resultats Le taux d’ E. coli sensible a l’association ticarcilline-acide clavulanique est eleve. De l’ordre de 85 % sans difference significative selon que les souches soient isolees de prelevements urinaires (87 % a 90 % selon la technique utilisee) ou des prelevements gastro-intestinaux (84 % a 87 %). Le nombre de souches presentant une beta-lactamase a spectre etendu est reduit mais en augmentation et necessite une surveillance. Taux de sensibilite aux antibiotiques (autres que β-lactamines) Les pourcentages de souches sensibles a l’acide nalidixique, la norfloxacine et la ciprofloxacine sont respectivement de 87,7 %, 89,4 % et 91,2 % sans difference significative selon l’origine des souches. Le pourcentage de sensibilite au cotrimoxazole est de 81,7 %. Conclusion Sur la base des donnees de notre etude, l’association ticarcilline-acide clavulanique peut etre une alternative au traitement des infections a E. coli .

Published
2007
Full Text
View/download PDF

35. Prévalence de la résistance d’Escherichia coli isolés de prélèvements d’origine urinaire ou gastro-intestinale vis-à-vis de l’association amoxicilline-acide clavulanique et de divers antibiotiques

Author

C. Rolland, F. Delpierre, S. Samaille, A. Decoster, S. Hendricx, D. Descamps, M. Roussel-Delvallez, R.J. Courcol, C. Cattoen, M. Vasseur, M. Menouar, M.N. Noulard, A. Vachée, M.P. Pelletier, N. Graveline, F. Wallet, J.G. Paul, M. Caillaux, and A. Verhaeghe

Subjects
Infectious Diseases, ácido clavulánico, Multicenter study, β lactams, Pharmacology (medical), Digestive tract, Acide clavulanique, Biology, Molecular biology, Biological fluid, Antibacterial agent
Abstract

Resume Cette etude evalue la prevalence de la resistance a l’amoxicilline-clavulanate d’ E. coli et analyse les resultats en fonction des differents tests de sensibilite utilises. Les souches testees avec l’ATB Expression sont plus resistantes qu’avec les methodes E-test ou de reference par dilution en gelose, ce qui induit un pourcentage de resistance d’ E. coli faussement eleve vis a vis de cet antibiotique. Le pourcentage d’ E. coli resistant a l’amoxicilline-clavulanate est bas : 3,2 % et 2 %, respectivement pour les souches isolees de prelevements d’origine gastro-intestinale et urinaire. De plus, 67 % des souches intermediaires ont une CMI de l’amoxicilline-clavulanate ≤ 8 mg/L. Les pourcentages de souches resistantes a l’acide nalidixique, la norfloxacine et la ciprofloxacine sont respectivement de 17,9 %, 11,3 % et 10,6 % pour les souches isolees de prelevements gastro-intestinaux et de 5 %, 8,5 % et 5,1 % pour celles isolees de prelevements urinaires. Devant cette augmentation de la resistance d’ E. coli aux fluoroquinolones, l’amoxicilline-clavulanate demeure une alternative au traitement des infections a E. coli .

Published
2007
Full Text
View/download PDF

36. [European Antibiotic Awareness Day: What is new in France?]

Author

C, Pulcini, S, Alfandari, F, Ballereau, E, Bonnet, F, Bruneel, B, Castan, C, Chidiac, R, Cohen, D, Descamps, T, Doco-Lecompte, R, Gauzit, B, Guéry, V, Jarlier, P, Lesprit, A G, Marcelin, J M, Molina, C, Rabaud, A, Riché, D, Salmon-Céron, E, Senneville, J P, Stahl, P, Tattevin, E, Varon, and F, Roblot

Subjects
Anniversaries and Special Events, Drug Resistance, Bacterial, Humans, France, Health Education, Anti-Bacterial Agents
Published
2015

37. Evaluating the management of 493 patients presenting with bacteremia in 23 northern French hospitals

Author

D. Descamps, P. Cabaret, A. Vachée, N. Van Grunderbeeck, C. Cattoen, Serge Alfandari, and S. Nguyen

Subjects
0301 basic medicine, Male, medicine.medical_specialty, Pediatrics, medicine.drug_class, 030106 microbiology, Antibiotics, Hospital Departments, Bacteremia, Hospitals, Private, Time-to-Treatment, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Intensive care, Drug Resistance, Multiple, Bacterial, Epidemiology, Medicine, Antimicrobial stewardship, Humans, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Aged, Aged, 80 and over, Cross Infection, Hematology, business.industry, Septic shock, Hospitals, Public, Disease Management, Middle Aged, medicine.disease, Shock, Septic, Anti-Bacterial Agents, Community-Acquired Infections, Infectious Diseases, Treatment Outcome, Female, France, Guideline Adherence, business
Abstract

Objectives We aimed to update the epidemiology of bacteremia and evaluate their management and short-term outcome. Methods We conducted a prospective multicenter survey from October to November 2011. Consecutive patients with at least one positive blood culture (BC) were included in the study. We evaluated the type and adequacy of empirical and documented antibiotic therapy, time to active antibiotic therapy, compliance with guidelines, and 10-day outcome. Results A total of 23 public and private hospitals and 633 patients (493 true pathogens and 140 contaminants) were included in the study. Patients’ wards were medicine (57%), surgery (19%), intensive care (14%), onco/hematology (3.7%), pediatrics (3.4%), infectious diseases (1.8%), and obstetrics (1.2%). Main pathogens were Escherichia coli (36%), Staphylococcus aureus (16%), coagulase-negative staphylococci, and Klebsiella sp. (8% each). A total of 43 (8.7%) multidrug-resistant strains were observed, including 26 extended-spectrum beta-lactamase strains and 15 methicillin-resistant S. aureus strains. An antibiotic active against the isolated pathogen was used in 74% of empirical and 96% of documented therapies. Median time between BC and administration of an active drug was 0.61 day. Empirical antibiotic therapies were protocol-compliant in 77% of cases. Few (4%) patients with contaminated BC received an antibiotic therapy (all inappropriate). Day-10 mortality was 12.1%, higher in patients presenting with severe sepsis or septic shock (22.5%) than in patients presenting with non-severe bacteremia (7.1%; P Conclusion The management of bacteremia seems satisfactory in these volunteer hospitals but bacteremia remains a severe infection.

Published
2015

38. Développement d'une source EUV plasma laser pour la micro-lithographie

Author

P. Haltebourg, J.-F. Hergott, F. Chichmanian, Didier Normand, E. Caprin, D. Descamps, T. Ceccotti, O. Sublemontier, M. Schmidt, Marc Segers, S. Hulin, and M. Bougeard

Subjects
General Physics and Astronomy
Abstract

Le Groupe des Applications Plasma (GAP) du CEA a Saclay participe au projet national PREUVE du Reseau Micro- et Nano-Technologies. Ce projet a ete lance fin 1999 pour reunir et developper les competences en France sur la lithographie dans l'extreme ultraviolet (LEUV). Au sein de PREUVE, notre objectif a ete le developpement d'une source plasma laser dans l'EUV autour de 13nm afin de contribuer a la realisation d'un premier banc d'essai pour la lithographie (BEL) en Europe. Afin de realiser cette source, nous utilisons un plasma emetteur qui est produit par l'interaction d'un laser de type Nd :YAG sur un jet de gouttelettes de xenon. A la fin du projet PREUVE, cette source satisfait les principales specifications et repond en particulier aux besoins en flux de photons EUV pour realiser des tests d'insolation EUV avec le banc d'essai. Suite a ces resultats prometteurs, nous demarrons actuellement un projet industriel EXULITE avec nos partenaires du CEA, d'Alcatel et de Thales sur le developpement d'une source EUV de puissance pour des machines de lithographie de production. Ce projet se terminera en 2005.

Published
2003
Full Text
View/download PDF

40. 32-fs Kerr-lens mode-locked Yb:CaGdAlO₄ oscillator optically pumped by a bright fiber laser

Author

P, Sévillano, P, Georges, F, Druon, D, Descamps, and E, Cormier

Abstract

In this study, we report on a pure Kerr-lens mode-locked Yb:CaGdAlO₄ oscillator optically pumped by a diffraction-limited fiber laser. At the repetition rate of 96 MHz, several configurations have been studied to achieve either pulse duration of 40 fs with average powers up to the watt level or shorter pulse duration down to 32 fs. To the best of our knowledge, this represents the shortest pulse duration ever achieved with an Yb-doped bulk material and the highest average power for sub-40-fs Kerr-lens mode-locked Yb-bulk oscillator.

Published
2014

41. Observatoire régional Pseudomonas aeruginosa du Nord-Pas-de-Calais: Données épidémiologiques et microbiologiques

Author

D. Descamps, C. Cattoen, T. Levent, Réseau de microbiologistes de l'ARECLIN, G. Beaucaire, Bruno Coignard, B. Grandbastien, and L. Bouillet

Subjects
Infectious Diseases, Geography, Nord pas de calais, Forestry, Antibacterial agent
Abstract

Resume Une etude d'incidence de Pseudomonas aeruginosa a ete menee en 1996 par 25 centres hospitaliers (13913 lits) de la region Nord-Pas-de-Calais. L'enquete s'est deroulee sur deux periodes trimestrielles durant lesquelles ces etablissements ont realise 230 018 entrees. L'incidence des patients infectes ou colonises par P. aeruginosa s'etablit a 9,4/1 000 admissions et rapportee a l'annee a 31,2/100 lits. Les incidences d'isolement calculees par discipline montrent des taux eleves pour les services de reanimation : 425,8 P. aeruginosa par an et pour 100 lits. Trois serotypes (O 11 , O 6 , O 4 ) representent plus de 40 % du recrutement. Les pourcentages de sensibilite aux antibiotiques (3 056 souches) sont de 66,5 % pour la ticarcilline, 84,7 % pour la ceftazidime, 82,2 % pour l'imipeneme, 73,3 % pour l'amikacine et 61,2 % pour la ciprofloxacine. Cette enquete confirme l'importance de P. aeruginosa dans les hopitaux de la region mais montre de tres grandes differences quant a la situation locale de chaque etablissement tant en termes d'incidence qu'en termes de niveau de resistance.

Published
1999
Full Text
View/download PDF

43. HIV-1 integrase variability and relationship with drug resistance in antiretroviral-naive and -experienced patients with different HIV-1 subtypes

Author

S, Reigadas, A G, Marcelin, A, Houssaïni, S, Yerly, D, Descamps, J C, Plantier, A, Ruffault, C, Amiel, M A, Trabaud, Philippe, Flandre, H, Fleury, B, Masquelier, S, Marque-Juillet, Microbiologie Fondamentale et Pathogénicité (MFP), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Epidémiologie, stratégies thérapeutiques et virologie cliniques dans l'infection à VIH, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de virologie [Rouen], Hôpital Charles Nicolle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Unité de Rétrovirologie, Hôpital Pontchaillou, Infectious Diseases Department, Université Montpellier 1 (UM1), Virology Laboratory, Bordeaux University Hospital, Bordeaux, France, Service de virologie et d'immunologie biologique, CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Microbiologie cellulaire et moléculaire et pathogénicité (MCMP), Service de virologie [CHU Pitié-Salpêtrière], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Université de Rouen Normandie (UNIROUEN), and Normandie Université (NU)-Normandie Université (NU)-Département de microbiologie : Bactério, Virologie, Parasito, Hygiène-Hôpital Charles Nicolle [Rouen]-CHU Rouen

Subjects
Microbiology (medical), Anti-HIV Agents, HIV Integrase/genetics, Molecular Sequence Data, Human immunodeficiency virus (HIV), Mutation, Missense, HIV Infections, Drug resistance, HIV Integrase, Bioinformatics, medicine.disease_cause, 03 medical and health sciences, Anti-HIV Agents/pharmacology, Drug Resistance, Viral, medicine, Antiretroviral naive, Humans, Pharmacology (medical), ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, ddc:616, HIV-1/drug effects/genetics/isolation & purification, Pharmacology, 0303 health sciences, biology, Group study, 030306 microbiology, Genetic Variation, Sequence Analysis, DNA, Hiv subtype, Virology, 3. Good health, Integrase, Infectious Diseases, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Hiv 1 integrase, biology.protein, HIV-1, HIV Infections/virology
Abstract

H-932. American Society for Microbiology, Washington, DC, USA. 10 Nouhin J, Donchai T, Hoang KT et al. Natural polymorphisms of HIV-1 CRF01_AE integrase coding region in ARV-naive individuals in Cambodia, Thailand and Vietnam: an ANRS AC12 working group study. Infect Genet Evol 2011; 11: 38–43. 11 Wainberg MA, Brenner BG. Role of HIV subtype diversity in the development of resistance to antiviral drugs. Viruses 2010; 2: 2493–508. Research letter

Published
2013

44. Interstitial cells of Cajal in human colon and in Hirschsprung's disease

Author

Jean-Jacques Vanderhaeghen, JJ Rumessen, D Descamps, M H De Laet, Jean-Marie Vanderwinden, and H Liu

Subjects
Male, Pathology, medicine.medical_specialty, Colon, Stem cell factor, digestive system, Receptor tyrosine kinase, symbols.namesake, Submucosa, medicine, Humans, Hirschsprung Disease, Hirschsprung's disease, Myenteric plexus, Stem Cell Factor, Hepatology, biology, Megacolon, Infant, Newborn, Gastroenterology, Infant, medicine.disease, digestive system diseases, Interstitial cell of Cajal, Proto-Oncogene Proteins c-kit, medicine.anatomical_structure, Child, Preschool, biology.protein, symbols, Immunohistochemistry, Female
Abstract

BACKGROUND & AIMS: Subpopulations of interstitial cells of Cajal are regarded as the source of spontaneous slow waves of the gut musculature (pacemaker cells). Their ontogeny remains unclear, but a role of the tyrosine kinase receptor c-kit in their development has recently been recognized. This study examined the interstitial cells in the human colon and in Hirschsprung's disease (aganglionosis). METHODS: The distribution of the c-kit receptor was studied using specific antibodies in 5 normal patients, 10 patients with Hirschsprung's disease, and 3 patients with diversion loop enterostomies. c-kit immunohistochemistry was also combined with reduced nicotinamide adenine dinucleotide phosphate diaphorase histochemistry or with c-kit ligand (stem cell factor) immunohistochemistry. Transmission electron microscopy was performed in 1 patient with Hirschsprung's disease. RESULTS: c-kit immunoreactivity labeled a network of interstitial cells at the outer edge of the submucosa, in the muscular layers, and around the myenteric plexus. In aganglionic segments, interstitial cells were scarce and its network appeared disrupted. Interstitial cells of Cajal were identified in aganglionic regions by electron microscopy. Interstitial cells of Cajal are identifiable in newborns and exhibit similar distribution in diversion loops independent of contact with luminal nutrients. CONCLUSIONS: Our morphological data may explain the abnormal spontaneous electrical activity in aganglionic segments of Hirschsprung's disease and may give new insight into the ontogeny of interstitial cells.

Published
1996
Full Text
View/download PDF

45. HIV-1 dynamics and coreceptor usage in Maraviroc-treated patients with ongoing replication

Author

P, Recordon-Pinson, S, Raymond, P, Bellecave, A G, Marcelin, C, Soulie, D, Descamps, V, Calvez, P R, Harrigan, H, Fleury, J, Izopet, B, Masquelier, Theresa, Mo, Microbiologie Fondamentale et Pathogénicité (MFP), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), Service de virologie et d'immunologie biologique, CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Virologie [CHU Toulouse], Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Epidémiologie, stratégies thérapeutiques et virologie cliniques dans l'infection à VIH, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Service de Virologie [CHU Bichat], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Numerical Medicine (NUMED), Unité de Mathématiques Pures et Appliquées (UMPA-ENSL), École normale supérieure de Lyon (ENS de Lyon)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Centre National de la Recherche Scientifique (CNRS)-Inria Grenoble - Rhône-Alpes, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), British Columbia Centre for Excellence in HIV/AIDS [Vancouver], Laboratoire de Virologie, BC Centre for Excellence in HIV/AIDS, ANRS AC11 Resistance Study Group, Microbiologie cellulaire et moléculaire et pathogénicité (MCMP), Laboratoire de Virologie [Purpan], CHU Toulouse [Toulouse]-Institut Fédératif de Biologie (IFB) - Hôpital Purpan, Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Virologie [Toulouse], Service de virologie [CHU Pitié-Salpêtrière], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Inria Grenoble - Rhône-Alpes, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Unité de Mathématiques Pures et Appliquées (UMPA-ENSL), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon), and Le Corre, Morgane

Subjects
MESH: Selection, Genetic, HIV Infections, HIV Envelope Protein gp120, V3 loop, MESH: Receptors, CCR5, Maraviroc, MESH: Genotype, MESH: HIV-1, chemistry.chemical_compound, MESH: HIV Envelope Protein gp120, HIV Fusion Inhibitors, Genotype, MESH: Sequence Analysis, RNA, Pharmacology (medical), MESH: Peptide Fragments, MESH: High-Throughput Nucleotide Sequencing, MESH: Evolution, Molecular, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Genetics, 0303 health sciences, education.field_of_study, MESH: Drug Resistance, Viral, High-Throughput Nucleotide Sequencing, virus diseases, MESH: HIV Infections, MESH: Cyclohexanes, 3. Good health, Infectious Diseases, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Viral evolution, CCR5 Receptor Antagonists, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Receptors, CXCR4, Receptors, CCR5, Population, Viral quasispecies, Biology, Antiviral Agents, MESH: Receptors, CXCR4, Evolution, Molecular, 03 medical and health sciences, Cyclohexanes, Drug Resistance, Viral, Humans, Selection, Genetic, education, MESH: HIV Fusion Inhibitors, Tropism, 030304 developmental biology, Pharmacology, MESH: Humans, Sequence Analysis, RNA, 030306 microbiology, Triazoles, Virology, Peptide Fragments, body regions, Viral Tropism, chemistry, MESH: Triazoles, HIV-1, Tissue tropism, MESH: Viral Tropism, human activities
Abstract

There is evidence that HIV-1 evolution under maraviroc (MVC) pressure can lead to the selection of either X4-tropic variants and/or R5-tropic, MVC-resistant isolates. However, the viral dynamics of HIV-1 variants in patients with virological failure (VF) on MVC-containing regimens remain poorly studied. Here, we investigated the V3 loop evolution of HIV-1 on MVC in relation to coreceptor usage and the nature of HIV-1 quasispecies before MVC therapy using bulk population sequences and ultradeep sequencing. The majority of patients had no detectable minority X4 variant at baseline. The evolution of tropism was followed up until VF and showed three possibilities for viral evolution in these patients: emergence of preexisting X4 variants, de novo selection of R5 variants presenting V3 loop mutations, or replication of R5 variants without selection of known mutations.

Published
2013
Full Text
View/download PDF

46. Candidémie a candida utilis chez un patient de réanimation, résistant au traitement par fluconazole

Author

T Desmettre, D Descamps, L Scala, S Dekeyser, D Belletante, and M.-C Dufossez

Subjects
Resuscitation, medicine.medical_specialty, Chemotherapy, biology, business.industry, medicine.medical_treatment, Fungi imperfecti, medicine.disease, biology.organism_classification, Gastroenterology, Catheter, Infectious Diseases, Intensive care, Internal medicine, medicine, business, Fluconazole, Mycosis, Fungemia, medicine.drug
Published
2003
Full Text
View/download PDF

47. [Bacteremia and French computerized disease surveillance system: financial valorisation of an infectious diseases specialist in a hospital]

Author

S, Nguyen, F, Dufossez, S, Dekeyser, and D, Descamps

Subjects
Cross Infection, Infectious Disease Medicine, Databases, Factual, Hospital Departments, Bacteremia, Anti-Bacterial Agents, Community-Acquired Infections, Vocabulary, Controlled, Cost Savings, Population Surveillance, Patients' Rooms, Medical Staff, Hospital, Humans, France, Hospital Costs, Surgery Department, Hospital
Abstract

Bacteremia surveillance is a mission assumed by the referent person for antimicrobial therapy. We propose an original financial valorization of this activity, using the computerized disease surveillance system (CDSS).A database collecting community-acquired and care-associated bacteremia was created on January 1, 2009 at the Bethune Hospital, France, using EPI-Info software (EPI Data). This database was used to complete missing data (presence of bacteremia, origin [community-acquired or care-associated], site of infection) in CDSS codes of patients hospitalized in surgical and medical wards (410 beds) during 2009. Financial benefit was assessed by the difference of funds allocated on the basis of CDSS, before and after completion of the missing data.In 2009, 383 out of the 35,000 patients presented with bacteremia. When missing CDSS codes were added, a financial gain of 229,291 euros was obtained, concerning 64 patients.Bacteremia surveillance is a transversal task based on quality of care, which may have a positive financial impact. This study may be helpful for clinicians with transversal activities, for whom financial valorization is difficult to implement in the CDSS, particularly without hospitalization beds. The lack of complete notification in the CDSS may cause a substantial financial loss.

Published
2010

48. [Implementation of vanA and vanB genes by PCR technique research interest in system (Xpert vanA/vanB CepheidR) closed in a laboratory of microbiology in managing an outbreak to Enterococcus faecium resistant glycopeptide (EfRG)]

Author

S, Dekeyser, E, Beclin, and D, Descamps

Subjects
Cross Infection, Enterococcus faecium, Glycopeptides, Laboratories, Hospital, Polymerase Chain Reaction, Sensitivity and Specificity, Anti-Bacterial Agents, Disease Outbreaks, Early Diagnosis, Bacterial Proteins, Computer Systems, Predictive Value of Tests, Drug Resistance, Multiple, Bacterial, Humans, France, Carbon-Oxygen Ligases, Gram-Positive Bacterial Infections
Abstract

The closed system PCR for the rapid detection of vanA and vanB genes (Xpert vanA/vanB Cepheid(®)) was evaluated in our laboratory, to improve the rapidity of the response and thus the management of patients and isolation measures during two GRE outbreaks.From March to December2009, 565 samples were analysed by PCR associated to bacterial culture initially for all samples for 2months (n = 75), and thereafter for PCR-positive samples only.In this study, sensitivity and negative predictive values of the PCR were 100%. Specificity was evaluated in the presence and absence of outbreak: 69.3 and 76.8% respectively. The variability of false positive rates between units were lower in nonepidemic than during epidemic phase. The global false positive rate was 23.9%.This easy-to-use technology provides rapid results… four samples are tested in 1h versus 72h for culture. Despite its reagent cost, it represents an important hospital diagnostic tool: improvement of the management of cohorting areas and patient transfer between units, adaptation of isolation measures and treatments. However, culture remains necessary to confirm any positive result obtained by PCR and for epidemiological surveillance.

Published
2010

49. Alignment of the CMS silicon tracker during commissioning with cosmic rays

Author

Chatrchyan, S. Khachatryan, V. Sirunyan, A. M. Adam, W. and Arnold, B. Bergauer, H. Bergauer, T. Dragicevic, M. and Eichberger, M. Eroe, J. Friedl, M. Fruehwirth, R. Ghete, V. M. Hammer, J. Haensel, S. Hoch, M. Hoermann, N. and Hrubec, J. Jeitler, M. Kasieczka, G. Kastner, K. and Krammer, M. Liko, D. de Abril, I. Magrans Mikulec, I. and Mittermayr, F. Neuherz, B. Oberegger, M. Padrta, M. and Pernicka, M. Rohringer, H. Schmid, S. Schoefbeck, R. and Schreiner, T. Stark, R. Steininger, H. Strauss, J. and Taurok, A. Teischinger, F. Themel, T. Uhl, D. Wagner, P. and Waltenberger, W. Walzel, G. Widl, E. Wulz, C. -E. and Chekhovsky, V. Dvornikov, O. Emeliantchik, I. Litomin, A. and Makarenko, V. Marfin, I. Mossolov, V. Shumeiko, N. and Solin, A. Stefanovitch, R. Gonzalez, J. Suarez Tikhonov, A. and Fedorov, A. Karneyeu, A. Korzhik, M. Panov, V. and Zuyeuski, R. Kuchinsky, P. Beaumont, W. Benucci, L. and Cardaci, M. De Wolf, E. A. Delmeire, E. Druzhkin, D. and Hashemi, M. Janssen, X. Maes, T. Mucibello, L. Ochesanu, S. Rougny, R. Selvaggi, M. Van Haevermaet, H. Van Mechelen, P. Van Remortel, N. Adler, V. Beauceron, S. and Blyweert, S. D'Hondt, J. De Weirdt, S. Devroede, O. and Heyninck, J. Kalogeropoulos, A. Maes, J. Maes, M. Mozer, M. U. Tavernier, S. Van Doninck, W. Van Mulders, P. and Villella, I. Bouhali, O. Chabert, E. C. Charaf, O. and Clerbaux, B. De Lentdecker, G. Dero, V. Elgammal, S. and Gay, A. P. R. Hammad, G. H. Marage, P. E. Rugovac, S. and Vander Velde, C. Vanlaer, P. Wickens, J. Grunewald, M. and Klein, B. Marinov, A. Ryckbosch, D. Thyssen, F. Tytgat, M. Vanelderen, L. Verwilligen, P. Basegmez, S. Bruno, G. and Caudron, J. Delaere, C. Demin, P. Favart, D. and Giammanco, A. Gregoire, G. Lemaitre, V. Militaru, O. and Ovyn, S. Piotrzkowski, K. Quertenmont, L. Schul, N. and Beliy, N. Daubie, E. Alves, G. A. Pol, M. E. Souza, M. H. G. Carvalho, W. De Jesus Damiao, D. De Oliveira Martins, C. Fonseca De Souza, S. Mundim, L. Oguri, V. Santoro, A. and Silva Do Amaral, S. M. Sznajder, A. Fernandez Perez Tomei, T. R. Ferreira Dias, M. A. Gregores, E. M. Novaes, S. F. and Abadjiev, K. Anguelov, T. Damgov, J. Darmenov, N. and Dimitrov, L. Genchev, V. Iaydjiev, P. Piperov, S. and Stoykova, S. Sultanov, G. Trayanov, R. Vankov, I. and Dimitrov, A. Dyulendarova, M. Kozhuharov, V. Litov, L. and Marinova, E. Mateev, M. Pavlov, B. Petkov, P. Toteva, Z. and Chen, G. M. Chen, H. S. Guan, W. Jiang, C. H. Liang, D. Liu, B. Meng, X. Tao, J. Wang, J. Wang, Z. and Xue, Z. Zhang, Z. Avila, C. Baquero Ruiz, M. Carrillo Montoya, C. A. Gomez, A. Gomez Moreno, B. Ocampo Rios, A. A. and Osorio Oliveros, A. F. Reyes Romero, D. Sanabria, J. C. and Godinovic, N. Lelas, K. Plestina, R. Polic, D. Puljak, I. Antunovic, Z. Dzelalija, M. Brigljevic, V. Duric, S. and Kadija, K. Morovic, S. Fereos, R. Galanti, M. Mousa, J. Papadakis, A. Ptochos, F. Razis, P. A. Tsiakkouri, D. and Zinonos, Z. Hektor, A. Kadastik, M. Kannike, K. and Muentel, M. Raidal, M. Rebane, L. Anttila, E. Czellar, S. Harkonen, J. Heikkinen, A. Karimaki, V. Kinnunen, R. and Klem, J. Kortelainen, M. J. Lampen, T. Lassila-Perini, K. Lehti, S. Linden, T. Luukka, P. Maenpaa, T. and Nysten, J. Tuominen, E. Tuominiemi, J. Ungaro, D. and Wendland, L. Banzuzi, K. Korpela, A. Tuuva, T. Nedelec, P. Sillou, D. Besancon, M. Chipaux, R. Dejardin, M. and Denegri, D. Descamps, J. Fabbro, B. Faure, J. L. Ferri, F. Ganjour, S. Gentit, F. X. Givernaud, A. Gras, P. and de Monchenault, G. Hamel Jarry, P. Lemaire, M. C. Locci, E. and Malcles, J. Marionneau, M. Millischer, L. Rander, J. and Rosowsky, A. Rousseau, D. Titov, M. Verrecchia, P. and Baffioni, S. Bianchini, L. Bluj, M. Busson, P. Charlot, C. Dobrzynski, L. de Cassagnac, R. Granier Haguenauer, M. and Mine, P. Paganini, P. Sirois, Y. Thiebaux, C. Zabi, A. Agram, J. -L. Besson, A. Bloch, D. Bodin, D. and Brom, J. -M. Conte, E. Drouhin, F. Fontaine, J. -C. and Gele, D. Goerlach, U. Gross, L. Juillot, P. Le Bihan, A. -C. Patois, Y. Speck, J. Van Hove, P. Baty, C. and Bedjidian, M. Blaha, J. Boudoul, G. Brun, H. Chanon, N. and Chierici, R. Contardo, D. Depasse, P. Dupasquier, T. and El Mamouni, H. Fassi, F. Fay, J. Gascon, S. Ille, B. and Kurca, T. Le Grand, T. Lethuillier, M. Lumb, N. and Mirabito, L. Perries, S. Vander Donckt, M. Verdier, P. and Djaoshvili, N. Roinishvili, N. Roinishvili, V. Amaglobeli, N. Adolphi, R. Anagnostou, G. Brauer, R. Braunschweig, W. Edelhoff, M. Esser, H. Feld, L. Karpinski, W. and Khomich, A. Klein, K. Mohr, N. Ostaptchouk, A. and Pandoulas, D. Pierschel, G. Raupach, F. Schael, S. von Dratzig, A. Schultz Schwering, G. Sprenger, D. Thomas, M. and Weber, M. Wittmer, B. Wlochal, M. Actis, O. and Altenhoefer, G. Bender, W. Biallass, P. Erdmann, M. and Fetchenhauer, G. Frangenheim, J. Hebbeker, T. Hilgers, G. and Hinzmann, A. Hoepfner, K. Hof, C. Kirsch, M. and Klimkovich, T. Kreuzer, P. Lanske, D. Merschmeyer, M. and Meyer, A. Philipps, B. Pieta, H. Reithler, H. Schmitz, S. A. Sonnenschein, L. Sowa, M. Steggemann, J. Szczesny, H. Teyssier, D. Zeidler, C. Bontenackels, M. Davids, M. and Duda, M. Fluegge, G. Geenen, H. Giffels, M. Ahmad, W. Haj Hermanns, T. Heydhausen, D. Kalinin, S. Kress, T. and Linn, A. Nowack, A. Perchalla, L. Poettgens, M. and Pooth, O. Sauerland, P. Stahl, A. Tornier, D. Zoeller, H. Martin, M. Aldaya Behrens, U. Borras, K. Campbell, A. and Castro, E. Dammann, D. Eckerlin, G. Flossdorf, A. and Flucke, G. Geiser, A. Hatton, D. Hauk, J. Jung, H. and Kasemann, M. Katkov, I. Kleinwort, C. Kluge, H. and Knutsson, A. Kuznetsova, E. Lange, W. Lohmann, W. and Mankel, R. Marienfeld, M. Meyer, A. B. Miglioranzi, S. and Mnich, J. Ohlerich, M. Olzem, J. Parenti, A. Rosemann, C. Schmidt, R. Schoerner-Sadenius, T. Volyanskyy, D. and Wissing, C. Zeuner, W. D. Autermann, C. Bechtel, F. and Draeger, J. Eckstein, D. Gebbert, U. Kaschube, K. and Kaussen, G. Klanner, R. Mura, B. Naumann-Emme, S. Nowak, F. Pein, U. Sander, C. Schleper, P. Schum, T. and Stadie, H. Steinbrueck, G. Thomsen, J. Wolf, R. Bauer, J. Bluem, P. Buege, V. Cakir, A. Chwalek, T. De Boer, W. Dierlamm, A. Dirkes, G. Feindt, M. Felzmann, U. and Frey, M. Furgeri, A. Gruschke, J. Hackstein, C. and Hartmann, F. Heier, S. Heinrich, M. Held, H. and Hirschbuehl, D. Hoffmann, K. H. Honc, S. Jung, C. Kuhr, T. Liamsuwan, T. Martschei, D. Mueller, S. Mueller, Th. and Neuland, M. B. Niegel, M. Oberst, O. Oehler, A. Ott, J. Peiffer, T. Piparo, D. Quast, G. Rabbertz, K. and Ratnikov, F. Ratnikova, N. Renz, M. Saout, C. Sartisohn, G. Scheurer, A. Schieferdecker, P. Schilling, F. -P. and Schott, G. Simonis, H. J. Stober, F. M. Sturm, P. and Troendle, D. Trunov, A. Wagner, W. Wagner-Kuhr, J. and Zeise, M. Zhukov, V. Ziebarth, E. B. Daskalakis, G. and Geralis, T. Karafasoulis, K. Kyriakis, A. Loukas, D. and Markou, A. Markou, C. Mavrommatis, C. Petrakou, E. and Zachariadou, A. Gouskos, L. Katsas, P. Panagiotou, A. and Evangelou, I. Kokkas, P. Manthos, N. Papadopoulos, I. and Patras, V. Triantis, F. A. Bencze, G. Boldizsar, L. and Debreczeni, G. Hajdu, C. Hernath, S. Hidas, P. Horvath, D. Krajczar, K. Laszlo, A. Patay, G. Sikler, F. and Toth, N. Vesztergombi, G. Beni, N. Christian, G. Imrek, J. Molnar, J. Novak, D. Palinkas, J. Szekely, G. and Szillasi, Z. Tokesi, K. Veszpremi, V. Kapusi, A. Marian, G. Raics, P. Szabo, Z. Trocsanyi, Z. L. Ujvari, B. and Zilizi, G. Bansal, S. Bawa, H. S. Beri, S. B. Bhatnagar, V. Jindal, M. Kaur, M. Kaur, R. Kohli, J. M. Mehta, M. Z. Nishu, N. Saini, L. K. Sharma, A. Singh, A. and Singh, J. B. Singh, S. P. Ahuja, S. Arora, S. and Bhattacharya, S. Chauhan, S. Choudhary, B. C. Gupta, P. and Jain, S. Jain, S. Jha, M. Kumar, A. Ranjan, K. and Shivpuri, R. K. Srivastava, A. K. Choudhury, R. K. Dutta, D. and Kailas, S. Kataria, S. K. Mohanty, A. K. Pant, L. M. and Shukla, P. Topkar, A. Aziz, T. Guchait, M. Gurtu, A. and Maity, M. Majumder, D. Majumder, G. Mazumdar, K. Nayak, A. Saha, A. Sudhakar, K. Banerjee, S. Dugad, S. and Mondal, N. K. Arfaei, H. Bakhshiansohi, H. Fahim, A. and Jafari, A. Najafabadi, M. Mohammadi Moshaii, A. Mehdiabadi, S. Paktinat Rouhani, S. Safarzadeh, B. Zeinali, M. and Felcini, M. Abbrescia, M. Barbone, L. Chiumarulo, F. and Clemente, A. Colaleo, A. Creanza, D. Cuscela, G. De Filippis, N. De Palma, M. De Robertis, G. Donvito, G. and Fedele, F. Fiore, L. Franco, M. Iaselli, G. Lacalamita, N. Loddo, F. Lusito, L. Maggi, G. Maggi, M. Manna, N. Marangelli, B. My, S. Natali, S. Nuzzo, S. and Papagni, G. Piccolomo, S. Pierro, G. A. Pinto, C. and Pompili, A. Pugliese, G. Rajan, R. Ranieri, A. Romano, F. Roselli, G. Selvaggi, G. Shinde, Y. Silvestris, L. and Tupputi, S. Zito, G. Abbiendi, G. Bacchi, W. and Benvenuti, A. C. Boldini, M. Bonacorsi, D. and Braibant-Giacomelli, S. Cafaro, V. D. Caiazza, S. S. and Capiluppi, P. Castro, A. Cavallo, F. R. Codispoti, G. and Cuffiani, M. D'Antone, I. Dallavalle, G. M. Fabbri, F. and Fanfani, A. Fasanella, D. Giacomelli, P. Giordano, V. and Giunta, M. Grandi, C. Guerzoni, M. Marcellini, S. and Masetti, G. Montanari, A. Navarria, F. L. Odorici, F. and Pellegrini, G. Perrotta, A. Rossi, A. M. Rovelli, T. and Siroli, G. Torromeo, G. Travaglini, R. Albergo, S. and Costa, S. Potenza, R. Tricomi, A. Tuve, C. Barbagli, G. and Broccolo, G. Ciulli, V. Civinini, C. D'Alessandro, R. and Focardi, E. Frosali, S. Gallo, E. Genta, C. Landi, G. Lenzi, P. Meschini, M. Paoletti, S. Sguazzoni, G. and Tropiano, A. Benussi, L. Bertani, M. Bianco, S. and Colafranceschi, S. Colonna, D. Fabbri, F. Giardoni, M. and Passamonti, L. Piccolo, D. Pierluigi, D. Ponzio, B. and Russo, A. Fabbricatore, P. Musenich, R. Benaglia, A. and Calloni, M. Cerati, G. B. D'Angelo, P. De Guio, F. and Farina, F. M. Ghezzi, A. Govoni, P. Malberti, M. and Malvezzi, S. Martelli, A. Menasce, D. Miccio, V. Moroni, L. Negri, P. Paganoni, M. Pedrini, D. Pullia, A. and Ragazzi, S. Redaelli, N. Sala, S. Salerno, R. de Fatis, T. Tabarelli Tancini, V. Taroni, S. Buontempo, S. and Cavallo, N. Cimmino, A. De Gruttola, M. Fabozzi, F. and Iorio, A. O. M. Lista, L. Lomidze, D. Noli, P. Paolucci, P. Sciacca, C. Azzi, P. Bacchetta, N. Barcellan, L. and Bellan, P. Bellato, M. Benettoni, M. Biasotto, M. and Bisello, D. Borsato, E. Branca, A. Carlin, R. and Castellani, L. Checchia, P. Conti, E. Dal Corso, F. De Mattia, M. Dorigo, T. Dosselli, U. Fanzago, F. and Gasparini, F. Gasparini, U. Giubilato, P. Gonella, F. and Gresele, A. Gulmini, M. Kaminskiy, A. Lacaprara, S. and Lazzizzera, I. Margoni, M. Maron, G. Mattiazzo, S. and Mazzucato, M. Meneghelli, M. Meneguzzo, A. T. Michelotto, M. and Montecassiano, F. Nespolo, M. Passaseo, M. Pegoraro, M. and Perrozzi, L. Pozzobon, N. Ronchese, P. Simonetto, F. and Toniolo, N. Torassa, E. Tosi, M. Triossi, A. Vanini, S. and Ventura, S. Zotto, P. Zumerle, G. Baesso, P. and Berzano, U. Bricola, S. Necchi, M. M. Pagano, D. Ratti, S. P. Riccardi, C. Torre, P. Vicini, A. Vitulo, P. and Viviani, C. Aisa, D. Aisa, S. Babucci, E. Biasini, M. and Bilei, G. M. Caponeri, B. Checcucci, B. Dinu, N. and Fano, L. Farnesini, L. Lariccia, P. Lucaroni, A. and Mantovani, G. Nappi, A. Piluso, A. Postolache, V. and Santocchia, A. Servoli, L. Tonoiu, D. Vedaee, A. Volpe, R. Azzurri, P. Bagliesi, G. Bernardini, J. Berretta, L. and Boccali, T. Bocci, A. Borrello, L. Bosi, F. and Calzolari, F. Castaldi, R. Dell'Orso, R. Fiori, F. Foa, L. Gennai, S. Giassi, A. Kraan, A. Ligabue, F. and Lomtadze, T. Mariani, F. Martini, L. Massa, M. Messineo, A. Moggi, A. Palla, F. Palmonari, F. Petragnani, G. and Petrucciani, G. Raffaelli, F. Sarkar, S. Segneri, G. and Serban, A. T. Spagnolo, P. Tenchini, R. Tolaini, S. and Tonelli, G. Venturi, A. Verdini, P. G. Baccaro, S. and Barone, L. Bartoloni, A. Cavallari, F. Dafinei, I. Del Re, D. Di Marco, E. Diemoz, M. Franci, D. Longo, E. and Organtini, G. Palma, A. Pandolfi, F. Paramatti, R. and Pellegrino, F. Rahatlou, S. Rovelli, C. Alampi, G. and Amapane, N. Arcidiacono, R. Argiro, S. Arneodo, M. and Biino, C. Borgia, M. A. Botta, C. Cartiglia, N. and Castello, R. Cerminara, G. Costa, M. Dattola, D. and Dellacasa, G. Demaria, N. Dughera, G. Dumitrache, F. and Graziano, A. Mariotti, C. Marone, M. Maselli, S. and Migliore, E. Mila, G. Monaco, V. Musich, M. Nervo, M. and Obertino, M. M. Oggero, S. Panero, R. Pastrone, N. and Pelliccioni, M. Romero, A. Ruspa, M. Sacchi, R. Solano, A. Staiano, A. Trapani, P. P. Trocino, D. Pereira, A. Vilela Visca, L. Zampieri, A. Ambroglini, F. Belforte, S. Cossutti, F. Della Ricca, G. Gobbo, B. Penzo, A. and Chang, S. Chung, J. Kim, D. H. Kim, G. N. Kong, D. J. and Park, H. Son, D. C. Bahk, S. Y. Song, S. Jung, S. Y. and Hong, B. Kim, H. Kim, J. H. Lee, K. S. Moon, D. H. and Park, S. K. Rhee, H. B. Sim, K. S. Kim, J. Choi, M. and Hahn, G. Park, I. C. Choi, S. Choi, Y. Goh, J. and Jeong, H. Kim, T. J. Lee, J. Lee, S. Janulis, M. and Martisiute, D. Petrov, P. Sabonis, T. Castilla Valdez, H. and Sanchez Hernandez, A. Carrillo Moreno, S. Morelos Pineda, A. and Allfrey, P. Gray, R. N. C. Krofcheck, D. Rodrigues, N. Bernardino Butler, P. H. Signal, T. Williams, J. C. and Ahmad, M. Ahmed, I. Ahmed, W. Asghar, M. I. Awan, M. I. M. Hoorani, H. R. Hussain, I. Khan, W. A. Khurshid, T. and Muhammad, S. Qazi, S. Shahzad, H. Cwiok, M. and Dabrowski, R. Dominik, W. Doroba, K. Konecki, M. and Krolikowski, J. Pozniak, K. Romaniuk, R. Zabolotny, W. and Zych, P. Frueboes, T. Gokieli, R. Goscilo, L. Gorski, M. and Kazana, M. Nawrocki, K. Szleper, M. Wrochna, G. and Zalewski, P. Almeida, N. Antunes Pedro, L. Bargassa, P. and David, A. Faccioli, P. Ferreira Parracho, P. G. Freitas Ferreira, M. Gallinaro, M. Guerra Jordao, M. Martins, P. and Mini, G. Musella, P. Pela, J. Raposo, L. Ribeiro, P. Q. and Sampaio, S. Seixas, J. Silva, J. Silva, P. Soares, D. Sousa, M. Varela, J. Wohri, H. K. Altsybeev, I. and Belotelov, I. Bunin, P. Ershov, Y. Filozova, I. Finger, M. Finger, Jr., M. Golunov, A. Golutvin, I. Gorbounov, N. Kalagin, V. Kamenev, A. Karjavin, V. Konoplyanikov, V. Korenkov, V. Kozlov, G. Kurenkov, A. Lanev, A. and Makankin, A. Mitsyn, V. V. Moisenz, P. Nikonov, E. and Oleynik, D. Palichik, V. Perelygin, V. Petrosyan, A. and Semenov, R. Shmatov, S. Smirnov, V. Smolin, D. and Tikhonenko, E. Vasil'ev, S. Vishnevskiy, A. Volodko, A. and Zarubin, A. Zhiltsov, V. Bondar, N. Chtchipounov, L. and Denisov, A. Gavrikov, Y. Gavrilov, G. Golovtsov, V. and Ivanov, Y. Kim, V. Kozlov, V. Levchenko, P. Obrant, G. and Orishchin, E. Petrunin, A. Shcheglov, Y. Shchetkovskiy, A. Sknar, V. Smirnov, I. Sulimov, V. Tarakanov, V. and Uvarov, L. Vavilov, S. Velichko, G. Volkov, S. Vorobyev, A. Andreev, Yu. Anisimov, A. Antipov, P. Dermenev, A. and Gninenko, S. Golubev, N. Kirsanov, M. Krasnikov, N. and Matveev, V. Pashenkov, A. Postoev, V. E. Solovey, A. and Solovey, A. Toropin, A. Troitsky, S. Baud, A. Epshteyn, V. Gavrilov, V. Ilina, N. Kaftanov, V. Kolosov, V. and Kossov, M. Krokhotin, A. Kuleshov, S. Oulianov, A. and Safronov, G. Semenov, S. Shreyber, I. Stolin, V. Vlasov, E. Zhokin, A. Boos, E. Dubinin, M. Dudko, L. Ershov, A. Gribushin, A. Klyukhin, V. Kodolova, O. Lokhtin, I. and Petrushanko, S. Sarycheva, L. Savrin, V. Snigirev, A. and Vardanyan, I. Dremin, I. Kirakosyan, M. Konovalova, N. and Rusakov, S. V. Vinogradov, A. Akimenko, S. Artamonov, A. and Azhgirey, I. Bitioukov, S. Burtovoy, V. Grishin, V. and Kachanov, V. Konstantinov, D. Krychkine, V. Levine, A. and Lobov, I. Lukanin, V. Mel'nik, Y. Petrov, V. Ryutin, R. and Slabospitsky, S. Sobol, A. Sytine, A. Tourtchanovitch, L. Troshin, S. Tyurin, N. Uzunian, A. Volkov, A. and Adzic, P. Djordjevic, M. Jovanovic, D. Krpic, D. and Maletic, D. Puzovic, J. Smiljkovic, N. Aguilar-Benitez, M. and Alberdi, J. Alcaraz Maestre, J. Arce, P. Barcala, J. M. and Battilana, C. Burgos Lazaro, C. Caballero Bejar, J. and Calvo, E. Cardenas Montes, M. Cepeda, M. Cerrada, M. and Chamizo Llatas, M. Clemente, F. Colino, N. Daniel, M. De La Cruz, B. Delgado Peris, A. Diez Pardos, C. Fernandez Bedoya, C. Fernandez Ramos, J. P. Ferrando, A. Flix, J. and Fouz, M. C. Garcia-Abia, P. Garcia-Bonilla, A. C. Gonzalez Lopez, O. Goy Lopez, S. Hernandez, J. M. Josa, M. I. and Marin, J. Merino, G. Molina, J. Molinero, A. Navarrete, J. J. Oller, J. C. Puerta Pelayo, J. Romero, L. and Santaolalla, J. Villanueva Munoz, C. Willmott, C. Yuste, C. and Albajar, C. Blanco Otano, M. de Troconiz, J. F. Garcia Raboso, A. Lopez Berengueres, J. O. Cuevas, J. Fernandez Menendez, J. Gonzalez Caballero, I. Lloret Iglesias, L. and Naves Sordo, H. Vizan Garcia, J. M. Cabrillo, I. J. and Calderon, A. Chuang, S. H. Diaz Merino, I. Diez Gonzalez, C. and Duarte Campderros, J. Fernandez, M. Gomez, G. Gonzalez Sanchez, J. Gonzalez Suarez, R. Jorda, C. Lobelle Pardo, P. and Lopez Virto, A. Marco, J. Marco, R. Martinez Rivero, C. and Martinez Ruiz del Arbol, P. Matorras, F. Rodrigo, T. and Ruiz Jimeno, A. Scodellaro, L. Sobron Sanudo, M. Vila, I. and Vilar Cortabitarte, R. Abbaneo, D. Albert, E. Alidra, M. and Ashby, S. Auffray, E. Baechler, J. Baillon, P. Ball, A. H. Bally, S. L. Barney, D. Beaudette, F. Bellan, R. and Benedetti, D. Benelli, G. Bernet, C. Bloch, P. and Bolognesi, S. Bona, M. Bos, J. Bourgeois, N. Bourrel, T. and Breuker, H. Bunkowski, K. Campi, D. Camporesi, T. and Cano, E. Cattai, A. Chatelain, J. P. Chauvey, M. and Christiansen, T. Perez, J. A. Coarasa Garcia, A. Conde and Covarelli, R. Cure, B. De Roeck, A. Delachenal, V. and Deyrail, D. Di Vincenzo, S. Dos Santos, S. Dupont, T. and Edera, L. M. Elliott-Peisert, A. Eppard, M. Favre, M. and Frank, N. Funk, W. Gaddi, A. Gastal, M. Gateau, M. and Gerwig, H. Gigi, D. Gill, K. Giordano, D. Girod, J. P. and Glege, F. Garrido, R. Gomez-Reino Goudard, R. Gowdy, S. and Guida, R. Guiducci, L. Gutleber, J. Hansen, M. and Hartl, C. Harvey, J. Hegner, B. Hoffmann, H. F. Holzner, A. Honma, A. Huhtinen, M. Innocente, V. Janot, P. Le Godec, G. Lecoq, P. Leonidopoulos, C. Loos, R. Lourenco, C. Lyonnet, A. Macpherson, A. Magini, N. Maillefaud, J. D. Maire, G. Maeki, T. Malgeri, L. Mannelli, M. and Masetti, L. Meijers, F. Meridiani, P. Mersi, S. Meschi, E. Cordonnier, A. Meynet Moser, R. Mulders, M. Mulon, J. and Noy, M. Oh, A. Olesen, G. Onnela, A. Orimoto, T. and Orsini, L. Perez, E. Perinic, G. Pernot, J. F. Petagna, P. Petiot, P. Petrilli, A. Pfeiffer, A. Pierini, M. and Pimiae, M. Pintus, R. Pirollet, B. Postema, H. Racz, A. and Ravat, S. Rew, S. B. Antunes, J. Rodrigues Rolandi, G. and Rovere, M. Ryjov, V. Sakulin, H. Samyn, D. Sauce, H. and Schaefer, C. Schlatter, W. D. Schroeder, M. Schwick, C. and Sciaba, A. Segoni, I. Sharma, A. Siegrist, N. and Siegrist, P. Sinanis, N. Sobrier, T. Sphicas, P. Spiga, D. Spiropulu, M. Stoeckli, F. Traczyk, P. Tropea, P. and Troska, J. Tsirou, A. Veillet, L. Veres, G. I. and Voutilainen, M. Wertelaers, P. Zanetti, M. Bertl, W. and Deiters, K. Erdmann, W. Gabathuler, K. Horisberger, R. and Ingram, Q. Kaestli, H. C. Koenig, S. Kotlinski, D. and Langenegger, U. Meier, F. Renker, D. Rohe, T. Sibille, J. Starodumov, A. Betev, B. Caminada, L. Chen, Z. and Cittolin, S. Di Calafiori, D. R. Da Silva Dambach, S. and Dissertori, G. Dittmar, M. Eggel, C. Eugster, J. Faber, G. Freudenreich, K. Grab, C. Herve, A. Hintz, W. and Lecomte, P. Luckey, P. D. Lustermann, W. Marchica, C. and Milenovic, P. Moortgat, F. Nardulli, A. Nessi-Tedaldi, F. and Pape, L. Pauss, F. Punz, T. Rizzi, A. Ronga, F. J. and Sala, L. Sanchez, A. K. Sawley, M. -C. Sordini, V. and Stieger, B. Tauscher, L. Thea, A. Theofilatos, K. and Treille, D. Trueb, P. Weber, M. Wehrli, L. Weng, J. and Zelepoukine, S. Amsler, C. Chiochia, V. De Visscher, S. and Regenfus, C. Robmann, P. Rommerskirchen, T. Schmidt, A. and Tsirigkas, D. Wilke, L. Chang, Y. H. Chen, E. A. Chen, W. T. Go, A. Kuo, C. M. Li, S. W. Lin, W. Bartalini, P. Chang, P. Chao, Y. Chen, K. F. Hou, W. -S. and Hsiung, Y. Lei, Y. J. Lin, S. W. Lu, R. -S. Schuemann, J. Shiu, J. G. Tzeng, Y. M. Ueno, K. Velikzhanin, Y. and Wang, C. C. Wang, M. Adiguzel, A. Ayhan, A. Gokce, A. Azman Bakirci, M. N. Cerci, S. Dumanoglu, I. Eskut, E. and Girgis, S. Gurpinar, E. Hos, I. Karaman, T. Karaman, T. Topaksu, A. Kayis Kurt, P. Oenenguet, G. Goekbulut, G. Oenenguet Ozdemir, K. Ozturk, S. Polatoez, A. Sogut, K. Tali, B. Topakli, H. Uzun, D. Vergili, L. N. and Vergili, M. Akin, I. V. Aliev, T. Bilmis, S. Deniz, M. and Gamsizkan, H. Guler, A. M. Oecalan, K. Serin, M. and Sever, R. Surat, U. E. Zeyrek, M. Deliomeroglu, M. and Demir, D. Guelmez, E. Halu, A. Isildak, B. Kaya, M. and Kaya, O. Ozkorucuklu, S. Sonmez, N. Levchuk, L. and Lukyanenko, S. Soroka, D. Zub, S. Bostock, F. Brooke, J. J. Cheng, T. L. Cussans, D. Frazier, R. Goldstein, J. and Grant, N. Hansen, M. Heath, G. P. Heath, H. F. Hill, C. Huckvale, B. Jackson, J. Mackay, C. K. Metson, S. and Newbold, D. M. Nirunpong, K. Smith, V. J. Velthuis, J. and Walton, R. Bell, K. W. Brew, C. Brown, R. M. Camanzi, B. and Cockerill, D. J. A. Coughlan, J. A. Geddes, N. I. and Harder, K. Harper, S. Kennedy, B. W. Murray, P. and Shepherd-Themistocleous, C. H. Tomalin, I. R. Williams, J. H. and Womersley, W. J. Worm, S. D. Bainbridge, R. Ball, G. and Ballin, J. Beuselinck, R. Buchmuller, O. Colling, D. and Cripps, N. Davies, G. Della Negra, M. Foudas, C. and Fulcher, J. Futyan, D. Hall, G. Hays, J. Iles, G. and Karapostoli, G. MacEvoy, B. C. Magnan, A. -M. Marrouche, J. and Nash, J. Nikitenko, A. Papageorgiou, A. Pesaresi, M. and Petridis, K. Pioppi, M. Raymond, D. M. Rompotis, N. and Rose, A. Ryan, M. J. Seez, C. Sharp, P. Sidiropoulos, G. and Stettler, M. Stoye, M. Takahashi, M. Tapper, A. and Timlin, C. Tourneur, S. Acosta, M. Vazquez Virdee, T. and Wakefield, S. Wardrope, D. Whyntie, T. Wingham, M. Cole, J. E. Goitom, I. Hobson, P. R. Khan, A. Kyberd, P. and Leslie, D. Munro, C. Reid, I. D. Siamitros, C. Taylor, R. Teodorescu, L. Yaselli, I. Bose, T. Carleton, M. and Hazen, E. Heering, A. H. Heister, A. John, J. St. and Lawson, P. Lazic, D. Osborne, D. Rohlf, J. Sulak, L. and Wu, S. Andrea, J. Avetisyan, A. Bhattacharya, S. Chou, J. P. Cutts, D. Esen, S. Kukartsev, G. Landsberg, G. and Narain, M. Nguyen, D. Speer, T. Tsang, K. V. Breedon, R. and Sanchez, M. Calderon De La Barca Case, M. Cebra, D. and Chertok, M. Conway, J. Cox, P. T. Dolen, J. Erbacher, R. and Friis, E. Ko, W. Kopecky, A. Lander, R. Lister, A. and Liu, H. Maruyama, S. Miceli, T. Nikolic, M. Pellett, D. Robles, J. Searle, M. Smith, J. Squires, M. and Stilley, J. Tripathi, M. Sierra, R. Vasquez Veelken, C. and Andreev, V. Arisaka, K. Cline, D. Cousins, R. Erhan, S. and Hauser, J. Ignatenko, M. Jarvis, C. Mumford, J. and Plager, C. Rakness, G. Schlein, P. Tucker, J. Valuev, V. and Wallny, R. Yang, X. Babb, J. Bose, M. Chandra, A. and Clare, R. Ellison, J. A. Gary, J. W. Hanson, G. and Jeng, G. Y. Kao, S. C. Liu, F. Liu, H. Luthra, A. and Nguyen, H. Pasztor, G. Satpathy, A. Shen, B. C. and Stringer, R. Sturdy, J. Sytnik, V. Wilken, R. Wimpenny, S. Branson, J. G. Dusinberre, E. Evans, D. Golf, F. and Kelley, R. Lebourgeois, M. Letts, J. Lipeles, E. and Mangano, B. Muelmenstaedt, J. Norman, M. Padhi, S. and Petrucci, A. Pi, H. Pieri, M. Ranieri, R. Sani, M. and Sharma, V. Simon, S. Wuerthwein, F. Yagil, A. and Campagnari, C. D'Alfonso, M. Danielson, T. Garberson, J. and Incandela, J. Justus, C. Kalavase, P. Koay, S. A. and Kovalskyi, D. Krutelyov, V. Lamb, J. Lowette, S. and Pavlunin, V. Rebassoo, F. Ribnik, J. Richman, J. Rossin, R. Stuart, D. To, W. Vlimant, J. R. Witherell, M. and Apresyan, A. Bornheim, A. Bunn, J. Chiorboli, M. and Gataullin, M. Kcira, D. Litvine, V. Ma, Y. Newman, H. B. and Rogan, C. Timciuc, V. Veverka, J. Wilkinson, R. and Yang, Y. Zhang, L. Zhu, K. Zhu, R. Y. Akgun, B. and Carroll, R. Ferguson, T. Jang, D. W. Jun, S. Y. Paulini, M. Russ, J. Terentyev, N. Vogel, H. Vorobiev, I. and Cumalat, J. P. Dinardo, M. E. Drell, B. R. Ford, W. T. and Heyburn, B. Lopez, E. Luiggi Nauenberg, U. Stenson, K. and Ulmer, K. Wagner, S. R. Zang, S. L. Agostino, L. and Alexander, J. Blekman, F. Cassel, D. Chatterjee, A. Das, S. Gibbons, L. K. Heltsley, B. Hopkins, W. and Khukhunaishvili, A. Kreis, B. Kuznetsov, V. Patterson, J. R. and Puigh, D. Ryd, A. Shi, X. Stroiney, S. Sun, W. and Teo, W. D. Thom, J. Vaughan, J. Weng, Y. Wittich, P. and Beetz, C. P. Cirino, G. Sanzeni, C. Winn, D. Abdullin, S. Afaq, M. A. Albrow, M. Ananthan, B. Apollinari, G. and Atac, M. Badgett, W. Bagby, L. Bakken, J. A. Baldin, B. Banerjee, S. Banicz, K. Bauerdick, L. A. T. Beretvas, A. Berryhill, J. Bhat, P. C. Biery, K. Binkley, M. and Bloch, I. Borcherding, F. Brett, A. M. Burkett, K. and Butler, J. N. Chetluru, V. Cheung, H. W. K. Chlebana, F. and Churin, I. Cihangir, S. Crawford, M. Dagenhart, W. and Demarteau, M. Derylo, G. Dykstra, D. Eartly, D. P. and Elias, J. E. Elvira, V. D. Evans, D. Feng, L. Fischler, M. Fisk, I. Foulkes, S. Freeman, J. Gartung, P. and Gottschalk, E. Grassi, T. Green, D. Guo, Y. Gutsche, O. and Hahn, A. Hanlon, J. Harris, R. M. Holzman, B. and Howell, J. Hufnagel, D. James, E. Jensen, H. Johnson, M. and Jones, C. D. Joshi, U. Juska, E. Kaiser, J. Klima, B. Kossiakov, S. Kousouris, K. Kwan, S. Lei, C. M. and Limon, P. Perez, J. A. Lopez Los, S. Lueking, L. and Lukhanin, G. Lusin, S. Lykken, J. Maeshima, K. and Marraffino, J. M. Mason, D. McBride, P. Miao, T. Mishra, K. Moccia, S. Mommsen, R. Mrenna, S. Muhammad, A. S. and Newman-Holmes, C. Noeding, C. O'Dell, V. Prokofyev, O. and Rivera, R. Rivetta, C. H. Ronzhin, A. Rossman, P. Ryu, S. Sekhri, V. Sexton-Kennedy, E. Sfiligoi, I. Sharma, S. and Shaw, T. M. Shpakov, D. Skup, E. Smith, R. P. Soha, A. Spalding, W. J. Spiegel, L. Suzuki, I. Tan, P. and Tanenbaum, W. Tkaczyk, S. Trentadue, R. Uplegger, L. and Vaandering, E. W. Vidal, R. Whitmore, J. Wicklund, E. and Wu, W. Yarba, J. Yumiceva, F. Yun, J. C. Acosta, D. and Avery, P. Barashko, V. Bourilkov, D. Chen, M. Di Giovanni, G. P. Dobur, D. Drozdetskiy, A. Field, R. D. and Fu, Y. Furic, I. K. Gartner, J. Holmes, D. Kim, B. and Klimenko, S. Konigsberg, J. Korytov, A. Kotov, K. and Kropivnitskaya, A. Kypreos, T. Madorsky, A. Matchev, K. and Mitselmakher, G. Pakhotin, Y. Gomez, J. Piedra Prescott, C. and Rapsevicius, V. Remington, R. Schmitt, M. Scurlock, B. and Wang, D. Yelton, J. Ceron, C. Gaultney, V. Kramer, L. Lebolo, L. M. Linn, S. Markowitz, P. Martinez, G. and Rodriguez, J. L. Adams, T. Askew, A. Baer, H. Bertoldi, M. Chen, J. Dharmaratna, W. G. D. Gleyzer, S. V. Haas, J. Hagopian, S. Hagopian, V. Jenkins, M. Johnson, K. F. and Prettner, E. Prosper, H. Sekmen, S. Baarmand, M. M. and Guragain, S. Hohlmann, M. Kalakhety, H. Mermerkaya, H. and Ralich, R. Vodopiyanov, I. Abelev, B. Adams, M. R. and Anghel, I. M. Apanasevich, L. Bazterra, V. E. Betts, R. R. and Callner, J. Castro, M. A. Cavanaugh, R. Dragoiu, C. and Garcia-Solis, E. J. Gerber, C. E. Hofman, D. J. Khalatian, S. Mironov, C. Shabalina, E. Smoron, A. Varelas, N. and Akgun, U. Albayrak, E. A. Ayan, A. S. Bilki, B. Briggs, R. Cankocak, K. Chung, K. Clarida, W. Debbins, P. and Duru, F. Ingram, F. D. Lae, C. K. McCliment, E. Merlo, J. -P. Mestvirishvili, A. Miller, M. J. Moeller, A. and Nachtman, J. Newsom, C. R. Norbeck, E. Olson, J. Onel, Y. Ozok, F. Parsons, J. Schmidt, I. Sen, S. Wetzel, J. Yetkin, T. Yi, K. Barnett, B. A. Blumenfeld, B. and Bonato, A. Chien, C. Y. Fehling, D. Giurgiu, G. Gritsan, A. V. Guo, Z. J. Maksimovic, P. Rappoccio, S. Swartz, M. and Tran, N. V. Zhang, Y. Baringer, P. Bean, A. Grachov, O. Murray, M. Radicci, V. Sanders, S. Wood, J. S. and Zhukova, V. Bandurin, D. Bolton, T. Kaadze, K. Liu, A. and Maravin, Y. Onoprienko, D. Svintradze, I. Wan, Z. and Gronberg, J. Hollar, J. Lange, D. Wright, D. Baden, D. and Bard, R. Boutemeur, M. Eno, S. C. Ferencek, D. and Hadley, N. J. Kellogg, R. G. Kirn, M. Kunori, S. and Rossato, K. Rumerio, P. Santanastasio, F. Skuja, A. and Temple, J. Tonjes, M. B. Tonwar, S. C. Toole, T. Twedt, E. Alver, B. Bauer, G. Bendavid, J. Busza, W. Butz, E. Cali, I. A. Chan, M. D'Enterria, D. Everaerts, P. and Ceballos, G. Gomez Hahn, K. A. Harris, P. Jaditz, S. and Kim, Y. Klute, M. Lee, Y. -J. Li, W. Loizides, C. and Ma, T. Miller, M. Nahn, S. Paus, C. Roland, C. and Roland, G. Rudolph, M. Stephans, G. Sumorok, K. Sung, K. and Vaurynovich, S. Wenger, E. A. Wyslouch, B. Xie, S. and Yilmaz, Y. Yoon, A. S. Bailleux, D. Cooper, S. I. and Cushman, P. Dahmes, B. De Benedetti, A. Dolgopolov, A. and Dudero, P. R. Egeland, R. Franzoni, G. Haupt, J. and Inyakin, A. Klapoetke, K. Kubota, Y. Mans, J. Mirman, N. and Petyt, D. Rekovic, V. Rusack, R. Schroeder, M. and Singovsky, A. Zhang, J. Cremaldi, L. M. Godang, R. and Kroeger, R. Perera, L. Rahmat, R. Sanders, D. A. Sonnek, P. Summers, D. Bloom, K. Bockelman, B. Bose, S. and Butt, J. Claes, D. R. Dominguez, A. Eads, M. Keller, J. and Kelly, T. Kravchenko, I. Lazo-Flores, J. Lundstedt, C. and Malbouisson, H. Malik, S. Snow, G. R. Baur, U. and Iashvili, I. Kharchilava, A. Kumar, A. Smith, K. Strang, M. Alverson, G. Barberis, E. Boeriu, O. Eulisse, G. and Govi, G. McCauley, T. Musienko, Y. Muzaffar, S. Osborne, I. Paul, T. Reucroft, S. Swain, J. Taylor, L. Tuura, L. Anastassov, A. Gobbi, B. Kubik, A. Ofierzynski, R. A. and Pozdnyakov, A. Schmitt, M. Stoynev, S. Velasco, M. and Won, S. Antonelli, L. Berry, D. Hildreth, M. Jessop, C. and Karmgard, D. J. Kolberg, T. Lannon, K. Lynch, S. and Marinelli, N. Morse, D. M. Ruchti, R. Slaunwhite, J. and Warchol, J. Wayne, M. Bylsma, B. Durkin, L. S. Gilmore, J. Gu, J. Killewald, P. Ling, T. Y. Williams, G. and Adam, N. Berry, E. Elmer, P. Garmash, A. Gerbaudo, D. and Halyo, V. Hunt, A. Jones, J. Laird, E. Marlow, D. and Medvedeva, T. Mooney, M. Olsen, J. Piroue, P. and Stickland, D. Tully, C. Werner, J. S. Wildish, T. Xie, Z. Zuranski, A. Acosta, J. G. Del Alamo, M. Bonnett and Huang, X. T. Lopez, A. Mendez, H. Oliveros, S. Vargas, J. E. Ramirez Santacruz, N. Zatzerklyany, A. Alagoz, E. and Antillon, E. Barnes, V. E. Bolla, G. Bortoletto, D. and Everett, A. Garfinkel, A. F. Gecse, Z. Gutay, L. and Ippolito, N. Jones, M. Koybasi, O. Laasanen, A. T. and Leonardo, N. Liu, C. Maroussov, V. Merkel, P. Miller, D. H. Neumeister, N. Sedov, A. Shipsey, I. Yoo, H. D. and Zheng, Y. Jindal, P. Parashar, N. Cuplov, V. Ecklund, K. M. Geurts, F. J. M. Liu, J. H. Maronde, D. Matveev, M. and Padley, B. P. Redjimi, R. Roberts, J. Sabbatini, L. and Tumanov, A. Betchart, B. Bodek, A. Budd, H. Chung, Y. S. and de Barbaro, P. Demina, R. Flacher, H. Gotra, Y. and Harel, A. Korjenevski, S. Miner, D. C. Orbaker, D. and Petrillo, G. Vishnevskiy, D. Zielinski, M. Bhatti, A. and Demortier, L. Goulianos, K. Hatakeyama, K. Lungu, G. and Mesropian, C. Yan, M. Atramentov, O. Bartz, E. and Gershtein, Y. Halkiadakis, E. Hits, D. Lath, A. Rose, K. and Schnetzer, S. Somalwar, S. Stone, R. Thomas, S. and Watts, T. L. Cerizza, G. Hollingsworth, M. Spanier, S. and Yang, Z. C. York, A. Asaadi, J. Aurisano, A. Eusebi, R. and Golyash, A. Gurrola, A. Kamon, T. Nguyen, C. N. and Pivarski, J. Safonov, A. Sengupta, S. Toback, D. and Weinberger, M. Akchurin, N. Berntzon, L. Gumus, K. and Jeong, C. Kim, H. Lee, S. W. Popescu, S. Roh, Y. and Sill, A. Volobouev, I. Washington, E. Wigmans, R. and Yazgan, E. Engh, D. Florez, C. Johns, W. Pathak, S. and Sheldon, P. Andelin, D. Arenton, M. W. Balazs, M. and Boutle, S. Buehler, M. Conetti, S. Cox, B. Hirosky, R. and Ledovskoy, A. Neu, C. Phillips, II, D. Ronquest, M. and Yohay, R. Gollapinni, S. Gunthoti, K. Harr, R. Karchin, P. E. Mattson, M. Sakharov, A. Anderson, M. Bachtis, M. and Bellinger, J. N. Carlsmith, D. Crotty, I. Dasu, S. and Dutta, S. Efron, J. Feyzi, F. Flood, K. Gray, L. and Grogg, K. S. Grothe, M. Hall-Wilton, R. Jaworski, M. and Klabbers, P. Klukas, J. Lanaro, A. Lazaridis, C. and Leonard, J. Loveless, R. de Abril, M. Magrans Mohapatra, A. and Ott, G. Polese, G. Reeder, D. Savin, A. Smith, W. H. and Sourkov, A. Swanson, J. Weinberg, M. Wenman, D. and Wensveen, M. White, A. CMS Collaboration

Subjects
Physics::Instrumentation and Detectors
Abstract

The CMS silicon tracker, consisting of 1440 silicon pixel and 15 148 silicon strip detector modules, has been aligned using more than three million cosmic ray charged particles, with additional information from optical surveys. The positions of the modules were determined with respect to cosmic ray trajectories to an average precision of 3-4 microns RMS in the barrel and 3-14 microns RMS in the endcap in the most sensitive coordinate. The results have been validated by several studies, including laser beam cross-checks, track fit self-consistency, track residuals in overlapping module regions, and track parameter resolution, and are compared with predictions obtained from simulation. Correlated systematic effects have been investigated. The track parameter resolutions obtained with this alignment are close to the design performance.

Published
2010

50. Observation of long-range, near-side angular correlations in proton-proton collisions at the LHC

Author

Khachatryan, V. Sirunyan, A. M. Tumasyan, A. Adam, W. and Bergauer, T. Dragicevic, M. Eroe, J. Fabjan, C. Friedl, M. Fruehwirth, R. Ghete, V. M. Hammer, J. Hansel, S. and Hartl, C. Hoch, M. Ormann, N. H. Hrubec, J. Jeitler, M. and Kasieczka, G. Kiesenhofer, W. Krammer, M. Liko, D. and Mikulec, I. Pernicka, M. Rohringer, H. Schoefbeck, R. and Strauss, J. Taurok, A. Teischinger, F. Waltenberger, W. and Walzel, G. Widl, E. Wulz, C. -E. Mossolov, V. Shumeiko, N. Gonzalez, J. Suarez Benucci, L. Ceard, L. De Wolf, E. A. Janssen, X. Macs, T. Mucibello, L. Ochesanu, S. and Roland, B. Rougny, R. Selvaggi, M. Van Haevermaet, H. and Van Mechelen, P. Van Remortel, N. Adler, V. Beauceron, S. and Blyweert, S. D'Hondt, J. Devroede, O. Kalogeropoulos, A. and Maes, J. Maes, M. Tavernier, S. Van Doninck, W. Van Mulders, P. Villella, I. Chabert, E. C. Charaf, O. and Clerbaux, B. De Lentdecker, G. Dero, V. Gay, A. P. R. and Hammad, G. H. Hreus, T. Marage, P. E. Velde, C. Vander and Vanlaer, P. Wickens, J. Costantini, S. Grunewald, M. and Klein, B. Marinov, A. Ryckbosch, D. Thyssen, F. Tytgat, M. Vanelderen, L. Verwilligen, P. Walsh, S. Zaganidis, N. Basegmez, S. Bruno, G. Caudron, J. de Jeneret, J. De Favereau Delaere, C. Demin, P. Favart, D. Giammanco, A. and Gregoire, G. Hollar, J. Lemaitre, V. Militaru, O. and Ovyn, S. Pagano, D. Pin, A. Piotrzkowski, K. and Quertenmont, L. Schul, N. Beliy, N. Caebergs, T. Daubie, E. Alves, G. A. Damiao, D. De Jesus Pol, M. E. Souza, M. H. G. Carvalho, W. Da Costa, E. M. Martins, C. De Oliveira and Fonseca De Souza, S. Mundim, L. Nogima, H. Oguri, V. and Goicochea, M. Otalora Da Silva, W. L. Prado Santoro, A. Do Amaral, S. M. Silva Sznajder, A. Da Silva De Araujo, F. Torres and Dias, F. A. Dias, M. A. F. Fernandez Perez Tomei, T. R. and Gregores, E. M. Marinho, F. Novaes, S. F. Padula, Sandra S. and Darmenov, N. Dimitrov, L. Genchev, V. Iaydjiev, P. and Piperov, S. Rodozov, M. Stoykova, S. Sultanov, G. and Tcholakov, V. Trayanov, R. Vankov, I. Dyulendarova, M. and Hadjiiska, R. Kozhuharov, V. Litov, L. Marinova, E. and Mateev, M. Pavlov, B. Petkov, P. Bian, J. G. Chen, G. M. and Chen, H. S. Jiang, C. H. Liang, D. Liang, S. Wang, J. Wang, J. Wang, X. Wang, Z. Yang, M. Zang, J. and Zhang, Z. Ban, Y. Guo, S. Hu, Z. Li, W. Mao, Y. and Qian, S. J. Teng, H. Zhu, B. Cabrera, A. Moreno, B. Gomez Rios, A. A. Ocampo Oliveros, A. F. Osorio Sanabria, J. C. Godinovic, N. Lelas, D. Lelas, K. Plestina, R. and Polic, D. Puljak, I. Antunovic, Z. Dzelalija, M. and Brigljevic, V. Duric, S. Kadija, K. Morovic, S. Attikis, A. Fereos, R. Galanti, M. Mousa, J. Nicolaou, C. and Ptochos, F. Razis, P. A. Rykaczewski, H. Assran, Y. and Mahmoud, M. A. Hektor, A. Kadastik, M. Muentel, M. and Raidal, M. Rebane, L. Azzolini, V. Eerola, P. Czellar, S. Harkonen, J. Heikkinen, A. Karimaki, V. Kinnunen, R. and Klem, J. Kortelainen, M. J. Lampen, T. Lassila-Perini, K. Lehti, S. Linden, T. Luukka, P. Maenpaa, T. and Tuominen, E. Tuominiemi, J. Tuovinen, E. Ungaro, D. and Wendland, L. Banzuzi, K. Korpela, A. Tuuva, T. Sillou, D. Besancon, M. Dejardin, M. Denegri, D. Descamps, J. and Fabbro, B. Faure, J. L. Ferri, F. Ganjour, S. and Gentit, F. X. Givernaud, A. Gras, P. de Monchenault, G. Hamel Jarry, P. Locci, E. Malcles, J. Marionneau, M. and Millischer, L. Rander, J. Rosowsky, A. Rousseau, D. and Titov, M. Verrecchia, P. Baffioni, S. Bianchini, L. and Bluj, M. Broutin, C. Busson, P. Charlot, C. Dobrzynski, L. de Cassagnac, R. Granier Haguenauer, M. Mine, P. and Mironov, C. Ochando, C. Paganini, P. Sabes, D. Salerno, R. Sirois, Y. Thiebaux, C. Zabi, A. Agram, J. -L. and Besson, A. Bloch, D. Bodin, D. Brom, J. -M. Cardaci, M. and Conte, E. Drouhin, F. Ferro, C. Fontaine, J. -C. and Gele, D. Goerlach, U. Greder, S. Juillot, P. Karim, M. and Le Bihan, A. -C. Mikami, Y. Van Hove, P. Fassi, F. and Mercier, D. Baty, C. Beaupere, N. Bedjidian, M. Bondu, O. Boudoul, G. Boumediene, D. Brun, H. Chanon, N. and Chierici, R. Contardo, D. Depasse, P. El Mamouni, H. and Falkiewicz, A. Fay, J. Gascon, S. Ille, B. Kurca, T. and Le Grand, T. Lethuillier, M. Mirabito, L. Perries, S. and Sordini, V. Tosi, S. Tschudi, Y. Verdier, P. Xiao, H. and Roinishvili, V. Anagnostou, G. Edelhoff, M. Feld, L. and Heracleous, N. Hindrichs, O. Jussen, R. Klein, K. Merz, J. Mohr, N. Ostapchuk, A. Perieanu, A. Raupach, F. and Sammet, J. Schael, S. Sprenger, D. Weber, H. Weber, M. and Wittmer, B. Ata, M. Bender, W. Erdmann, M. and Frangenheim, J. Hebbeker, T. Hinzmann, A. Hoepfner, K. and Hof, C. Klimkovich, T. Klingebiel, D. Kreuzer, P. and Lanske, D. Magass, C. Masetti, G. Merschmeyer, M. Meyer, A. Papacz, P. Pieta, H. Reithler, H. Schmitz, S. A. and Sonnenschein, L. Steggemann, J. Teyssier, D. Bontenackels, M. Davids, M. Duda, M. Flueggee, G. Geenen, H. and Giffels, M. Ahmad, W. Haj Heydhausen, D. Kress, T. and Kuessel, Y. Linn, A. Nowack, A. Perchalla, L. Pooth, O. and Rennefeld, J. Sauerland, P. Stahl, A. Thomas, M. and Tornier, D. Zoeller, M. H. Martin, M. Aldaya Behrenhoff, W. and Behrens, U. Bergholz, M. Borras, K. Campbell, A. and Castro, E. Dammann, D. Eckerlin, G. Flossdorf, A. and Flucke, G. Geiser, A. Glushkov, I. Hauk, J. Jung, H. and Kasemann, M. Katkov, I. Katsas, P. Kleinwort, C. Kluge, H. Knutsson, A. Kruecker, D. Kuznetsova, E. Lange, W. and Lohmann, W. Mankel, R. Marienfeld, M. Melzer-Pellmann, I. -A. Meyer, A. B. Mnich, J. Mussgiller, A. Olzem, J. and Parenti, A. Raspereza, A. Raval, A. Schmidt, R. and Schoerner-Sadenius, T. Sen, N. Stein, M. Tomaszewska, J. and Volyanskyy, D. Walsh, R. Wissing, C. Autermann, C. and Bobrovskyi, S. Draeger, J. Eckstein, D. Enderle, H. and Gebbert, U. Kaschube, K. Kaussen, G. Klanner, R. Mura, B. Naumann-Emme, S. Nowak, F. Pietsch, N. Sander, C. and Schettler, H. Schleper, P. Schroeder, M. Schum, T. and Schwandt, J. Srivastava, A. K. Stadie, H. Steinbrueck, G. and Thomsen, J. Wolf, R. Bauer, J. Buege, V. Cakir, A. and Chwalek, T. Daeuwel, D. De Boer, W. Dierlamm, A. and Dirkes, G. Feindt, M. Gruschke, J. Hackstein, C. and Hartmann, F. Heinrich, M. Held, H. Hoffmann, K. H. Honc, S. Kuhr, T. Martschei, D. Mueller, S. Mueller, Th. and Neuland, M. B. Niegel, M. Oberst, O. Oehler, A. Ott, J. and Peiffer, T. Piparo, D. Quast, G. Rabbertz, K. and Ratnikov, F. Renz, M. Sabellek, A. Saout, C. Scheurer, A. Schieferdecker, P. Schilling, F. -P. Schott, G. and Simonis, H. J. Stober, F. M. Troendle, D. Wagner-Kuhr, J. and Zeise, M. Zhukov, V. Ziebarth, E. B. Daskalakis, G. and Geralis, T. Kesisoglou, S. Kyriakis, A. Loukas, D. and Manolakos, I. Markou, A. Markou, C. Mavrommatis, C. and Petrakou, E. Gouskos, L. Mertzimekis, T. Panagiotou, A. and Evangelou, I. Kokkas, P. Manthos, N. Papadopoulos, I. and Patras, V. Triantis, F. A. Aranyi, A. Bencze, G. and Boldizsar, L. Debreczeni, G. Hajdu, C. Horvath, D. and Kapusi, A. Krajczar, K. Laszlo, A. Sikler, F. and Vesztergombi, G. Beni, N. Molnar, J. Palinkas, J. and Szillasi, Z. Veszpremi, V. Raics, P. Trocsanyi, Z. L. and Ujvari, B. Bansal, S. Beri, S. B. Bhatnagar, V. Jindal, M. Kaur, M. Kohli, J. M. Mehta, M. Z. Nishu, N. and Saini, L. K. Sharma, A. Sharma, R. Singh, A. P. Singh, J. B. Singh, S. P. Ahuja, S. Bhattacharya, S. Chauhan, S. Choudhary, B. C. Gupta, P. Jain, S. Jain, S. and Kumar, A. Shivpuri, R. K. Choudhury, R. K. Dutta, D. and Kailas, S. Kataria, S. K. Mohanty, A. K. Pant, L. M. and Shukla, P. Suggisetti, P. Aziz, T. Guchait, M. Gurtu, A. and Maity, M. Majumder, D. Majumder, G. Mazumdar, K. and Mohanty, G. B. Saha, A. Sudhakar, K. Wickramage, N. and Banerjee, S. Dugad, S. Mondal, N. K. Arfaei, H. and Bakhshiansohi, H. Etesami, S. M. Fahim, A. Hashemi, M. and Jafari, A. Khakzad, M. Mohammadi, A. Najafabadi, M. Mohammadi Mehdiabadi, S. Paktinat Safarzadeh, B. Zeinali, M. and Abbrescia, M. Barbone, L. Calabria, C. Colaleo, A. and Creanza, D. De Filippis, N. De Palma, M. Dimitrov, A. and Fedele, F. Fiore, L. Iaselli, G. Lusito, L. Maggi, G. and Maggi, M. Manna, N. Marangelli, B. My, S. Nuzzo, S. and Pierro, G. A. Pompili, A. Pugliese, G. Romano, F. and Roselli, G. Selvaggi, G. Silvestris, L. Trentadue, R. and Tupputi, S. Zito, G. Abbiendi, G. Benvenuti, A. C. and Bonacorsi, D. Braibant-Giacomelli, S. Capiluppi, P. Castro, A. Cavallo, F. R. Cuffiani, M. Dallavalle, G. M. Fabbri, F. Fanfani, A. Fasanella, D. Giacomelli, P. Giunta, M. and Grandi, C. Marcellini, S. Meneghelli, M. Montanari, A. and Navarria, F. L. Odorici, F. Perrotta, A. Rossi, A. M. and Rovelli, T. Siroli, G. Travaglini, R. Albergo, S. and Cappello, G. Chiorboli, M. Costa, S. Tricomi, A. Tuve, C. Barbagli, G. Broccolo, G. Ciulli, V. Civinini, C. and D'Alessandro, R. Focardi, E. Frosali, S. Gallo, E. and Lenzi, P. Meschini, M. Paoletti, S. Sguazzoni, G. and Tropiano, A. Benussi, L. Bianco, S. Colafranceschi, S. and Fabbri, F. Piccolo, D. Fabbricatore, P. Musenich, R. and Benaglia, A. Cerati, G. B. De Guio, F. Di Matteo, L. and Ghezzi, A. Govoni, P. Malberti, M. Malvezzi, S. and Martelli, A. Massironi, A. Menasce, D. Miccio, V. and Moroni, L. Paganoni, M. Pedrini, D. Ragazzi, S. and Redaelli, N. Sala, S. de Fatis, T. Tabarelli Tancini, V. and Buontempo, S. Montoya, C. A. Carrillo Cimmino, A. De Cosa, A. De Gruttola, M. Fabozzi, F. Iorio, A. O. M. Lista, L. and Noli, P. Paolucci, P. Azzi, P. Bacchetta, N. Bellan, P. Bisello, D. Branca, A. Carlin, R. Checchia, P. and Conti, E. De Mattia, M. Dorigo, T. Dosselli, U. Fanzago, F. Gasparini, F. Gasparini, U. Giubilato, P. Gresele, A. and Lacaprara, S. Lazzizzera, I. Margoni, M. Mazzucato, M. and Meneguzzo, A. T. Perrozzi, L. Pozzobon, N. Ronchese, P. and Simonetto, F. Torassa, E. Tosi, M. Vanini, S. Zotto, P. Zumerle, G. Baesso, P. Berzano, U. Riccardi, C. and Torre, P. Vitulo, P. Viviani, C. Biasini, M. Bilei, G. M. Caponeri, B. Fano, L. Lariccia, P. Lucaroni, A. and Mantovani, G. Menichelli, M. Nappi, A. Santocchia, A. and Servoli, L. Taroni, S. Valdata, M. Volpe, R. Azzurri, P. and Bagliesi, G. Bernardini, J. Boccali, T. Castaldi, R. and D'Agnolo, R. T. Dell'Orso, R. Fiori, F. Foa, L. Giassi, A. Kraan, A. Ligabue, F. Lomtadze, T. Martini, L. and Messineo, A. Palla, F. Palmonari, F. Sarkar, S. Segneri, G. Serban, A. T. Spagnolo, P. Tenchini, R. Tonelli, G. and Venturi, A. Verdini, P. G. Barone, L. Cavallari, F. and Del Re, D. Di Marco, E. Diemoz, M. Franci, D. Grassi, M. and Longo, E. Organtini, G. Palma, A. Pandolfi, F. and Paramatti, R. Rahatlou, S. Amapane, N. Arcidiacono, R. and Argiro, S. Arneodo, M. Biino, C. Botta, C. Cartiglia, N. and Castello, R. Costa, M. Demaria, N. Graziano, A. and Mariotti, C. Marone, M. Maselli, S. Migliore, E. Mila, G. Monaco, V. Musich, M. Obertino, M. M. Pastrone, N. and Pelliccioni, M. Romero, A. Ruspa, M. Sacchi, R. and Sola, V. Solano, A. Staiano, A. Trocino, D. Pereira, A. Vilela Ambroglini, F. Belforte, S. Cossutti, F. Della Ricca, G. Gobbo, B. Montanino, D. Penzo, A. Heo, S. G. and Chang, S. Chung, J. Kim, D. H. Kim, G. N. Kim, J. E. and Kong, D. J. Park, H. Son, D. Son, D. C. Kim, Zero and Kim, J. Y. Song, S. Choi, S. Hong, B. Jo, M. and Kim, H. Kim, J. H. Kim, T. J. Lee, K. S. Moon, D. H. and Park, S. K. Rhee, H. B. Seo, E. Shin, S. Sim, K. S. and Choi, M. Kang, S. Kim, H. Park, C. Park, I. C. Park, S. Ryu, G. Choi, Y. Choi, Y. K. Goh, J. Lee, J. and Lee, S. Seo, H. Yu, I. Bilinskas, M. J. Grigelionis, I. and Janulis, M. Martisiute, D. Petrov, P. Sabonis, T. and Castilla Valdez, H. De La Cruz Burelo, E. Lopez-Fernandez, R. and Sanchez Hernandez, A. Villasenor-Cendejas, L. M. Carrillo Moreno, S. Vazquez Valencia, F. Salazar Ibarguen, H. A. and Casimiro Linares, E. Morelos Pineda, A. Reyes-Santos, M. A. and Allfrey, P. Krofcheck, D. Tam, J. Butler, P. H. and Doesburg, R. Silverwood, H. Ahmad, M. Ahmed, I. Asghar, M. I. Hoorani, H. R. Khan, W. A. Khurshid, T. Qazi, S. and Cwiok, M. Dominik, W. Doroba, K. Kalinowski, A. and Konecki, M. Krolikowski, J. Frueboes, T. Gokieli, R. and Gorski, M. Kazana, M. Nawrocki, K. Szleper, M. Wrochna, G. Zalewski, P. Almeida, N. David, A. Faccioli, P. and Parracho, P. G. Ferreira Gallinaro, M. Martins, P. Mini, G. and Musella, P. Nayak, A. Raposo, L. Ribeiro, P. Q. and Seixas, J. Silva, P. Soares, D. Varela, J. Woehri, H. K. and Belotelov, I. Bunin, P. Finger, M. Finger, Jr., M. and Golutvin, I. Kamenev, A. Karjavin, V. Kozlov, G. Lanev, A. Moisenz, P. Palichik, V. Perelygin, V. Shmatov, S. and Smirnov, V. Volodko, A. Zarubin, A. Bondar, N. and Golovtsov, V. Ivanov, Y. Kim, V. Levchenko, P. Murzin, V. Oreshkin, V. Smirnov, I. Sulimov, V. Uvarov, L. and Vavilov, S. Vorobyev, A. Andreev, Yu. Gninenko, S. and Golubev, N. Kirsanov, M. Krasnikov, N. Matveev, V. and Pashenkov, A. Toropin, A. Troitsky, S. Epshteyn, V. and Gavrilov, V. Kaftanov, V. Kossov, M. Krokhotin, A. and Kuleshov, S. Lychkovskaya, N. Oulianov, A. Safronov, G. and Semenov, S. Shreyber, I. Stolin, V. Vlasov, E. Zhokin, A. Boos, E. Dubinin, M. Dudko, L. Ershov, A. and Gribushin, A. Kodolova, O. Lokhtin, I. Obraztsov, S. and Petrushanko, S. Sarycheva, L. Savrin, V. Snigirev, A. and Andreev, V. Azarkin, M. Dremin, I. Kirakosyan, M. and Rusakov, S. V. Vinogradov, A. Azhgirey, I. Bitioukov, S. and Grishin, V. Kachanov, V. Konstantinov, D. Krychkine, V. and Petrov, V. Ryutin, R. Slabospitsky, S. Sobol, A. and Tourtchanovitch, L. Troshin, S. Tyurin, N. Uzunian, A. and Volkov, A. Adzic, P. Djordjevic, M. Krpic, D. Maletic, D. Milosevic, J. Puzovic, J. Aguilar-Benitez, M. Alcaraz Maestre, J. Arce, P. Battilana, C. Calvo, E. Cepeda, M. and Cerrada, M. Colino, N. De La Cruz, B. Diez Pardos, C. and Fernandez Bedoya, C. Fernandez Ramos, J. P. Ferrando, A. and Flix, J. Fouz, M. C. Garcia-Abia, P. Gonzalez Lopez, O. and Goy Lopez, S. Hernandez, J. M. Josa, M. I. Merino, G. and Puerta Pelayo, J. Redondo, I. Romero, L. Santaolalla, J. and Willmott, C. Albajar, C. Codispoti, G. de Troconiz, J. F. and Cuevas, J. Fernandez Menendez, J. Folgueras, S. Gonzalez Caballero, I. Lloret Iglesias, L. Vizan Garcia, J. M. and Cabrillo, I. J. Calderon, A. Chamizo Llatas, M. Chuang, S. H. Diaz Merino, I. Diez Gonzalez, C. Duarte Campderros, J. and Felcini, M. Fernandez, M. Gomez, G. Gonzalez Sanchez, J. and Gonzalez Suarez, R. Jorda, C. Lobelle Pardo, P. Lopez Virto, A. Marco, J. Marco, R. Martinez Rivero, C. and Matorras, F. Piedra Gomez, J. Rodrigo, T. Ruiz Jimeno, A. and Scodellaro, L. Sobron Sanudo, M. Vila, I. Vilar Cortabitarte, R. Abbaneo, D. Auffray, E. Baillon, P. and Ball, A. H. Barney, D. Beaudette, F. Bell, A. J. and Benedetti, D. Bernet, C. Bhattacharyya, A. K. Bialas, W. and Bloch, P. Bocci, A. Bolognesi, S. Breuker, H. Brona, G. and Bunkowski, K. Camporesi, T. Cano, E. Cattai, A. and Cerminara, G. Christiansen, T. Perez, J. A. Coarasa and Covarelli, R. Cure, B. D'Enterria, D. Dahms, T. De Roeck, A. Elliott-Peisert, A. Funk, W. Gaddi, A. Gennai, S. Georgiou, G. Gerwig, H. Gigi, D. Gill, K. and Giordano, D. Glege, F. Garrido, R. Gomez-Reino Gouzevitch, M. Gowdy, S. Guiducci, L. Hansen, M. Harvey, J. and Hegeman, J. Hegner, B. Henderson, C. Hoffmann, H. F. and Honma, A. Innocente, V. Janot, P. Karavakis, E. Lecoq, P. Leonidopoulos, C. Lourenco, C. Macpherson, A. Maki, T. Malgeri, L. Mannelli, M. Masetti, L. Meijers, F. and Mersi, S. Meschi, E. Moser, R. Mozer, M. U. Mulders, M. and Nesvold, E. Orsini, L. Perez, E. Petrilli, A. and Pfeiffer, A. Pierini, M. Pimiae, M. Polese, G. Racz, A. and Rolandi, G. Rovelli, C. Rovere, M. Sakulin, H. and Schaefer, C. Schwick, C. Segoni, I. Sharma, A. Siegrist, P. Simon, M. Sphicas, P. Spiga, D. Spiropulu, M. and Stoeckli, F. Stoye, M. Tropea, P. Tsirou, A. Veres, G. I. Vichoudis, P. Voutilainen, M. Zeuner, W. D. Bertl, W. and Deiters, K. Erdmann, W. Gabathuler, K. Horisberger, R. and Ingram, Q. Kaestli, H. C. Koenig, S. Kotlinski, D. and Langenegger, U. Meier, F. Renker, D. Rohe, T. Sibille, J. Starodumov, A. Caminada, L. Chen, Z. Cittolin, S. and Dissertori, G. Dittmar, M. Eugster, J. Freudenreich, K. and Grab, C. Herve, A. Hintz, W. Lecomte, P. Lustermann, W. and Marchica, C. del Arbol, P. Martinez Ruiz Meridiani, P. and Milenovic, P. Moortgat, F. Nardulli, A. Nef, P. and Nessi-Tedaldi, F. Pape, L. Pauss, F. Punz, T. Rizzi, A. and Ronga, F. J. Sala, L. Sanchez, A. K. Sawley, M. -C. and Stieger, B. Tauscher, L. Thea, A. Latos, K. Theo Fi and Treille, D. Urscheler, C. Wallny, R. Weber, M. Wehrli, L. Weng, J. Aguilo, E. Amsler, C. Chiochia, V. De Visscher, S. Favaro, C. Rikova, M. Ivova Jaeger, A. and Mejias, B. Millan Regenfus, C. Robmann, P. Rommerskirchen, T. Schmidt, A. Snoek, H. Wilke, L. Chang, Y. H. and Chen, K. H. Chen, W. T. Dutta, S. Go, A. Kuo, C. M. and Li, S. W. Lin, W. Liu, M. H. Liu, Z. K. Lu, Y. J. and Wu, J. H. Yu, S. S. Bartalini, P. Chang, P. Chang, Y. H. and Chang, Y. W. Chao, Y. Chen, K. F. Hou, W. -S. and Hsiung, Y. Kao, K. Y. Lei, Y. J. Lu, R. -S. Shiu, J. G. and Tzeng, Y. M. Wang, M. Wei, J. T. Adiguzel, A. and Bakirci, M. N. Cerci, S. Demir, Z. Dozen, C. Dumanoglu, I. Eskut, E. Girgis, S. Gokbulut, G. Guler, Y. and Gurpinar, E. Hos, I. Kangal, E. E. Karaman, T. Topaksu, A. Kayis Nart, A. Onengut, G. Ozdemir, K. Ozturk, S. and Polatoz, A. Sogut, K. Tali, B. Topakli, H. Uzun, D. and Vergili, L. N. Vergili, M. Zorbilmez, C. Akin, I. V. and Aliev, T. Bilmis, S. Deniz, M. Gamsizkan, H. Guler, A. M. Ocalan, K. Ozpineci, A. Serin, M. Sever, R. and Surat, U. E. Yildirim, E. Zeyrek, M. Deliomeroglu, M. and Demir, D. Gulmez, E. Halu, A. Isildak, B. Kaya, M. and Kaya, O. Ozbek, M. Ozkorucuklu, S. Sonmez, N. Levchuk, L. Bell, P. Bostock, F. Brooke, J. J. Cheng, T. L. and Cussans, D. Frazier, R. Goldstein, J. Grimes, M. Hansen, M. Heath, G. P. Heath, H. F. Hill, C. Huckvale, B. and Jackson, J. Kreczko, L. Metson, S. Newbold, D. M. and Nirunpong, K. Poll, A. Smith, V. J. Ward, S. Basso, L. and Bell, K. W. Belyaev, A. Brew, C. Brown, R. M. and Camanzi, B. Cockerill, D. J. A. Coughlan, J. A. Harder, K. and Harper, S. Kennedy, B. W. Olaiya, E. Petyt, D. and Radburn-Smith, B. C. Shepherd-Themistocleous, C. H. Tomalin, I. R. Womersley, W. J. Worm, S. D. Bainbridge, R. Ball, G. and Ballin, J. Beuselinck, R. Buchmuller, O. Colling, D. and Cripps, N. Cutajar, M. Davies, G. Della Negra, M. and Foudas, C. Fulcher, J. Futyan, D. Bryer, A. Guneratne and Hall, G. Hatherell, Z. Hays, J. Iles, G. Karapostoli, G. and Lyons, L. Magnan, A. -M. Marrouche, J. Nandi, R. and Nash, J. Nikitenko, A. Papageorgiou, A. Pesaresi, M. and Petridis, K. Pioppi, M. Raymond, D. M. Rompotis, N. and Rose, A. Ryan, M. J. Seez, C. Sharp, P. Sparrow, A. and Tapper, A. Tourneur, S. Acosta, M. Vazquez Virdee, T. and Wakefield, S. Wardrope, D. Whyntie, T. Barrett, M. and Chadwick, M. Cole, J. E. Hobson, P. R. Khan, A. Kyberd, P. Leslie, D. Martin, W. Reid, I. D. Teodorescu, L. and Hatakeyama, K. Bose, T. Jarrin, E. Carrera Clough, A. and Fantasia, C. Heister, A. St John, J. Lawson, P. Lazic, D. Rohlf, J. Sulak, L. Andrea, J. Avetisyan, A. and Bhattacharya, S. Chou, J. P. Cutts, D. Esen, S. and Ferapontov, A. Heintz, U. Jabeen, S. Kukartsev, G. and Landsberg, G. Narain, M. Nguyen, D. Segala, M. Speer, T. and Tsang, K. V. Borgia, M. A. Breedon, R. Sanchez, M. Calderon De La Barca Cebra, D. Chertok, M. Conway, J. and Cox, P. T. Dolen, J. Erbacher, R. Friis, E. Ko, W. and Kopecky, A. Lander, R. Liu, H. Maruyama, S. Miceli, T. and Nikolic, M. Pellett, D. Robles, J. Schwarz, T. and Searle, M. Smith, J. Squires, M. Tripathi, M. Sierra, R. Vasquez Veelken, C. Andreev, V. Arisaka, K. Cline, D. and Cousins, R. Deisher, A. Duris, J. Erhan, S. Farrell, C. Hauser, J. Ignatenko, M. Jarvis, C. Plager, C. and Rakness, G. Schlein, P. Tucker, J. Valuev, V. Babb, J. and Clare, R. Ellison, J. Gary, J. W. Giordano, F. and Hanson, G. Jeng, G. Y. Kao, S. C. Liu, F. Liu, H. and Luthra, A. Nguyen, H. Pasztor, G. Satpathy, A. Shen, B. C. Stringer, R. Sturdy, J. Sumowidagdo, S. Wilken, R. and Wimpenny, S. Andrews, W. Branson, J. G. Dusinberre, E. and Evans, D. Golf, F. Holzner, A. Kelley, R. and Lebourgeois, M. Letts, J. Mangano, B. Muelmenstaedt, J. and Padhi, S. Palmer, C. Petrucciani, G. Pi, H. Pieri, M. and Ranieri, R. Sani, M. Sharma, V. Simon, S. Tu, Y. and Vartak, A. Wuerthwein, F. Yagil, A. Barge, D. Bellan, R. and Campagnari, C. D'Alfonso, M. Danielson, T. Ert, P. Ge Ff and Incandela, J. Justus, C. Kalavase, P. Koay, S. A. and Kovalskyi, D. Krutelyov, V. Lowette, S. Mccoll, N. and Pavlunin, V. Rebassoo, F. Ribnik, J. Richman, J. Rossin, R. Stuart, D. To, W. Vlimant, J. R. Witherell, M. and Bornheim, A. Bunn, J. Chen, Y. Gataullin, M. Kcira, D. and Litvine, V. Ma, Y. Mott, A. Newman, H. B. Rogan, C. and Shin, K. Timciuc, V. Traczyk, P. Veverka, J. and Wilkinson, R. Yang, Y. Zhu, R. Y. Akgun, B. Calamba, A. and Carroll, R. Ferguson, T. Iiyama, Y. Jang, D. W. Jun, S. Y. Liu, Y. F. Paulini, M. Russ, J. Terentyev, N. and Vogel, H. Vorobiev, I. Cumalat, J. P. Dinardo, M. E. and Drell, B. R. Edelmaier, C. J. Ford, W. T. Heyburn, B. and Lopez, E. Luiggi Nauenberg, U. Smith, J. G. Stenson, K. and Ulmer, K. A. Wagner, S. R. Zang, S. L. Agostino, L. and Alexander, J. Blekman, F. Chatterjee, A. Das, S. Eggert, N. Fields, L. J. Gibbons, L. K. Heltsley, B. Henriksson, K. Hopkins, W. Khukhunaishvili, A. Kreis, B. Kuznetsov, V. Liu, Y. Kaufman, G. Nicolas Patterson, J. R. Puigh, D. Riley, D. Ryd, A. Saelim, M. Shi, X. Sun, W. and Teo, W. D. Thom, J. Thompson, J. Vaughan, J. Weng, Y. and Wittich, P. Biselli, A. Cirino, G. Winn, D. and Abdullin, S. Albrow, M. Anderson, J. Apollinari, G. and Atac, M. Bakken, J. A. Banerjee, S. Bauerdick, L. A. T. and Beretvas, A. Berryhill, J. Bhat, P. C. Bloch, I. and Borcherding, F. Burkett, K. Butler, J. N. Chetluru, V. and Cheung, H. W. K. Chlebana, F. Cihangir, S. Demarteau, M. and Eartly, D. P. Elvira, V. D. Fisk, I. Freeman, J. Gao, Y. and Gottschalk, E. Green, D. Gunthoti, K. Gutsche, O. and Hahn, A. Hanlon, J. Harris, R. M. Hirschauer, J. James, E. Jensen, H. Johnson, M. Joshi, U. Khatiwada, R. and Kilminster, B. Klima, B. Kousouris, K. Kunori, S. Kwan, S. Limon, P. Lipton, R. Lykken, J. Maeshima, K. No, J. M. Marra Ffi Mason, D. McBride, P. McCauley, T. Miao, T. Mishra, K. Mrenna, S. Musienko, Y. Newman-Holmes, C. and O'Dell, V. Popescu, S. Pordes, R. Prokofyev, O. and Saoulidou, N. Sexton-Kennedy, E. Sharma, S. Soha, A. and Spalding, W. J. Spiegel, L. Tan, P. Taylor, L. Tkaczyk, S. Uplegger, L. Vaandering, E. W. Vidal, R. Whitmore, J. and Wu, W. Yang, F. Yumiceva, F. Yun, J. C. Acosta, D. and Avery, P. Bourilkov, D. Chen, M. Di Giovanni, G. P. and Dobur, D. Drozdetskiy, A. Field, R. D. Fisher, M. Fu, Y. and Furic, I. K. Gartner, J. Goldberg, S. Kim, B. and Klimenko, S. Konigsberg, J. Korytov, A. Kotov, K. and Kropivnitskaya, A. Kypreos, T. Matchev, K. Mitselmakher, G. and Muniz, L. Pakhotin, Y. Petterson, M. Prescott, C. and Remington, R. Schmitt, M. Scurlock, B. Sellers, P. and Snowball, M. Wang, D. Yelton, J. Zakaria, M. Ceron, C. and Gaultney, V. Kramer, L. Lebolo, L. M. Linn, S. and Markowitz, P. Martinez, G. Mesa, D. Rodriguez, J. L. and Adams, T. Askew, A. Bochenek, J. Chen, J. Diamond, B. and Gleyzer, S. V. Haas, J. Hagopian, S. Hagopian, V. and Jenkins, M. Johnson, K. F. Prosper, H. Sekmen, S. and Veeraraghavan, V. Baarmand, M. M. Dorney, B. Guragain, S. and Hohlmann, M. Kalakhety, H. Ralich, R. Vodopiyanov, I. and Adams, M. R. Anghel, I. M. Apanasevich, L. Bai, Y. and Bazterra, V. E. Betts, R. R. Callner, J. Cavanaugh, R. and Dragoiu, C. Garcia-Solis, E. J. Gerber, C. E. Hofman, D. J. and Khalatyan, S. Lacroix, F. O'Brien, C. Shabalina, E. and Silvestre, C. Smoron, A. Strom, D. Varelas, N. Akgun, U. and Albayrak, E. A. Bilki, B. Cankocak, K. Clarida, W. and Duru, F. Lae, C. K. McCliment, E. Merlo, J. -P. and Mermerkaya, H. Mestvirishvili, A. Moeller, A. Nachtman, J. and Newsom, C. R. Norbeck, E. Olson, J. Onel, Y. Ozok, F. Sen, S. Wetzel, J. Yetkin, T. Yi, K. Barnett, B. A. Blumenfeld, B. Bonato, A. Eskew, C. Fehling, D. and Giurgiu, G. Gritsan, A. V. Guo, Z. J. Hu, G. Maksimovic, P. Rappoccio, S. Swartz, M. Tran, N. V. Whitbeck, A. and Baringer, P. Bean, A. Benelli, G. Grachov, O. Murray, M. and Noonan, D. Radicci, V. Sanders, S. Wood, J. S. and Zhukova, V. Bandurin, D. Bolton, T. Chakaberia, I. and Ivanov, A. Makouski, M. Maravin, Y. Shrestha, S. and Svintradze, I. Wan, Z. Gronberg, J. Lange, D. Wright, D. and Baden, A. Boutemeur, M. Eno, S. C. Ferencek, D. and Gomez, J. A. Hadley, N. J. Kellogg, R. G. Kirn, M. Lu, Y. Mignerey, A. C. Rossato, K. Rumerio, P. and Santanastasio, F. Skuja, A. Temple, J. Tonjes, M. B. and Tonwar, S. C. Twedt, E. Alver, B. Bauer, G. Bendavid, J. and Busza, W. Butz, E. Cali, I. A. Chan, M. Dutta, V. and Everaerts, P. Ceballos, G. Gomez Goncharov, M. Hahn, K. A. Harris, P. Kim, Y. Klute, M. Lee, Y. -J. Li, W. and Loizides, C. Luckey, P. D. Ma, T. Nahn, S. Paus, C. and Roland, C. Roland, G. Rudolph, M. Stephans, G. S. F. and Sumorok, K. Sung, K. Wenger, E. A. Wyslouch, B. Xie, S. and Yang, M. Yilmaz, Y. Yoon, A. S. Zanetti, M. Cole, P. and Cooper, S. I. Cushman, P. Dahmes, B. De Benedetti, A. and Dudero, P. R. Franzoni, G. Haupt, J. Klapoetke, K. and Kubota, Y. Mans, J. Rekovic, V. Rusack, R. Sasseville, M. Singovsky, A. Cremaldi, L. M. Godang, R. Kroeger, R. and Perera, L. Rahmat, R. Sanders, D. A. Summers, D. and Bloom, K. Bose, S. Butt, J. Claes, D. R. Dominguez, A. and Eads, M. Keller, J. Kelly, T. Kravchenko, I. and Lazo-Flores, J. Lundstedt, C. Malbouisson, H. Malik, S. and Snow, G. R. Baur, U. Godshalk, A. Iashvili, I. and Kharchilava, A. Kumar, A. Smith, K. Zennamo, J. and Alverson, G. Barberis, E. Baumgartel, D. Boeriu, O. and Chasco, M. Kaadze, K. Reucroft, S. Swain, J. Wood, D. and Zhang, J. Anastassov, A. Kubik, A. Odell, N. and Ofierzynski, R. A. Pollack, B. Pozdnyakov, A. Schmitt, M. and Stoynev, S. Velasco, M. Won, S. Antonelli, L. Berry, D. Hildreth, M. Jessop, C. Karmgard, D. J. Kolb, J. and Kolberg, T. Lannon, K. Luo, W. Lynch, S. Marinelli, N. and Morse, D. M. Pearson, T. Ruchti, R. Slaunwhite, J. and Valls, N. Warchol, J. Wayne, M. Ziegler, J. Bylsma, B. and Durkin, L. S. Gu, J. Killewald, P. Ling, T. Y. and Rodenburg, M. Williams, G. Adam, N. Berry, E. Elmer, P. and Gerbaudo, D. Halyo, V. Hebda, P. Hunt, A. Jones, J. and Laird, E. Pegna, D. Lopes Marlow, D. Medvedeva, T. and Mooney, M. Olsen, J. Piroue, P. Saka, H. Stickland, D. and Tully, C. Werner, J. S. Zuranski, A. Acosta, J. G. and Huang, X. T. Lopez, A. Mendez, H. Oliveros, S. Vargas, J. E. Ramirez Zatserklyaniy, A. Alagoz, E. Barnes, V. E. and Bolla, G. Borrello, L. Bortoletto, D. Everett, A. and Garfinkel, A. F. Gecse, Z. Gutay, L. Jones, M. Koybasi, O. Laasanen, A. T. Leonardo, N. Liu, C. Maroussov, V. and Meier, M. Merkel, P. Miller, D. H. Neumeister, N. and Potamianos, K. Shipsey, I. Silvers, D. Svyatkovskiy, A. and Yoo, H. D. Zablocki, J. Zheng, Y. Jindal, P. Parashar, N. Boulahouache, C. Cuplov, V. Ecklund, K. M. Geurts, F. J. M. Liu, J. H. Morales, J. Padley, B. P. Redjimi, R. and Roberts, J. Zabel, J. Betchart, B. Bodek, A. Chung, Y. S. de Barbaro, P. Demina, R. Eshaq, Y. Flacher, H. and Garcia-Bellido, A. Goldenzweig, P. Gotra, Y. Han, J. and Harel, A. Miner, D. C. Orbaker, D. Petrillo, G. and Vishnevskiy, D. Zielinski, M. Bhatti, A. Demortier, L. and Goulianos, K. Lungu, G. Mesropian, C. Yan, M. and Atramentov, O. Barker, A. Duggan, D. Gershtein, Y. Gray, R. Halkiadakis, E. Hidas, D. Hits, D. Lath, A. and Panwalkar, S. Patel, R. Richards, A. Rose, K. Schnetzer, S. Somalwar, S. Stone, R. Thomas, S. Cerizza, G. and Hollingsworth, M. Spanier, S. Yang, Z. C. York, A. and Asaadi, J. Eusebi, R. Gilmore, J. Gurrola, A. Kamon, T. and Khotilovich, V. Montalvo, R. Nguyen, C. N. Pivarski, J. and Safonov, A. Sengupta, S. Tatarinov, A. Toback, D. and Weinberger, M. Akchurin, N. Bardak, C. Damgov, J. Jeong, C. Kovitanggoon, K. Lee, S. W. Mane, P. Roh, Y. and Sill, A. Volobouev, I. Wigmans, R. Yazgan, E. Appelt, E. and Brownson, E. Engh, D. Florez, C. Gabella, W. Johns, W. Kurt, P. Maguire, C. Melo, A. Sheldon, P. and Velkovska, J. Arenton, M. W. Balazs, M. Boutle, S. and Buehler, M. Conetti, S. Cox, B. Francis, B. Hirosky, R. and Ledovskoy, A. Lin, C. Neu, C. Patel, T. Yohay, R. and Gollapinni, S. Harr, R. Karchin, P. E. Loggins, V. and Mattson, M. Milstene, C. Sakharov, A. Anderson, M. and Bachtis, M. Bellinger, J. N. Carlsmith, D. Dasu, S. and Efron, J. Gray, L. Grogg, K. S. Grothe, M. Hall-Wilton, R. Herndon, M. Klabbers, P. Klukas, J. Lanaro, A. and Lazaridis, C. Leonard, J. Liu, J. Lomidze, D. Loveless, R. Mohapatra, A. Parker, W. Reeder, D. Ross, I. and Savin, A. Smith, W. H. Swanson, J. Weinberg, M. CMS Collaboration

Subjects
High Energy Physics::Experiment, Nuclear Experiment
Abstract

Results on two-particle angular correlations for charged particles emitted in proton-proton collisions at center-of-mass energies of 0.9, 2.36, and 7TeV are presented, using data collected with the CMS detector over a broad range of pseudorapidity (eta) and azimuthal angle (phi). Short-range correlations in Delta(eta), which are studied in minimum bias events, are characterized using a simple “independent cluster” parametrization in order to quantify their strength (cluster size) and their extent in eta (cluster decay width). Long-range azimuthal correlations are studied differentially as a function of charged particle multiplicity and particle transverse momentum using a 980 nb(-1) data set at 7TeV. In high multiplicity events, a pronounced structure emerges in the two-dimensional correlation function for particle pairs with intermediate p(T) of 1-3 GeV/c, 2.0

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results