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2. Industry Perspectives

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A. De Domenico, R. Gerzaguet, N. Cassiau, A. Clemente, R. D'Errico, C. Dehos, J. L. Gonzalez, D. Ktenas, L. Manat, V. Savin, A. Siligaris

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2017
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9. The rapid atmospheric monitoring system of the Pierre Auger Observatory

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Abreu, P., Aglietta, M, Ahlers, M., Ahn, M., Albuquerque, E. J., Allard, I. F. M., Allekotte, D., Allen, I., Allison, J., Almela, P., Castillo, A., Alvarez Muniz, J. A., Batista, J., Ambrosio, R. A., Aminaei, M., Anchordoqui, A., Andringa, L., Antici'C, S., Aramo, T., Arganda, C., Arqueros, E., Asorey, F., Assis, H., Aublin, P., Ave, J., Avenier, M., Avila, M., Badescu, G., Balzer, A. M., Barber, M., Barbosa, K. B., Bardenet, A. F., Barroso, R., Baughman, S. L. C., Bauml, B., Baus, J., Beatty, C., Becker, J. J., Belletoile, K. H., Bellido, A., Benzvi, J. A., Berat, S., Bertou, C., Biermann, X., Billoir, P. L., Blanco, P., Blanco, F., Bleve, M., Blumer, C., Bohacova, H., Boncioli, M., Bonifazi, D., Bonino, C., Borodai, R., Brack, N., Brancus, J., Brogueira, I., Brown, P., Bruijn, W. C., Buchholz, R., Bueno, P., Buroker, A., Burton, L., Caballero Mora, R. E., Caccianiga, K. S., Caramete, B., Caruso, L., Castellina, R., Catalano, A., Cataldi, O., Cazon, G., Cester, L., Chauvin, R., Cheng, J., Chiavassa, S. H., Chinellato, A., Diaz, J. A., Chudoba, J. C., Cilmo, J., Clay, M., Cocciolo, R. W., Collica, G., Coluccia, L., Conceicao, M. R., Contreras, R., Cook, F., Cooper, H., Coppens, M. J., Cordier, J., Coutu, A., Covault, S., Creusot, C. E., Criss, A., Cronin, A., Curutiu, J., Dagoret Campagne, A., Dallier, S., Daniel, R., Dasso, B., Daumiller, S., Dawson, K., de Almeida, B. R., De Domenico, R. M., De Donato, M., de Jong, C., De la Vega, S. J., de Mello, G., Neto, W. J. M., Mitri, Jrtd, de Souza, I., de Vries, V., del Peral, K. D., del Rio, L., Deligny, M., Dembinski, O., Dhital, H., Di Giulio, N., Castro, C., Diep, M. L. D., Diogo, P. N., Dobrigkeit, F., Docters, C., D'Olivo, W., Dong, J. C., Dorofeev, P. N., dos Anjos, A., Dova, J. C., D'Urso, M. T., Dutan, D., Ebr, I., Engel, J., Erdmann, R., Escobar, M., Espadanal, C. O., Etchegoyen, J., Luis, A., Falcke, P. F. S., Fang, H., Farrar, K., Fauth, G., Fazzini, A. C., Ferguson, N., Fick, A. P., Figueira, B., Filevich, J. M., Filipcic, A., Fliescher, A., Fracchiolla, S., Fraenkel, C. E., Fratu, E. D., Frohlich, O., Fuchs, U., Gaior, B., Gamarra, R., Gambetta, R. F., Garcia, S., Roca, B., Garcia Gamez, S. T. G., Garcia Pinto, D., Garilli, D., Bravo, G., Gemmeke, A. G., Ghia, H., Giller, P. L., Gitto, M., Glass, J., Gold, H., Golup, M. S., Albarracin, G., Berisso, F. G., Vitale, M. G., Goncalves, P. F. G., Gonzalez, P., Gookin, G., Gorgi, B., Gouffon, A., Grashorn, P., Grebe, E., Griffith, S., Grillo, N., Guardincerri, A. F., Guarino, Y., Guedes, F., Hansen, G. P., Harari, P., Harrison, D., Harton, T. A., Haungs, J. L., Hebbeker, A., Heck, T., Herve, D., Hojvat, A. E., Hollon, C., Holmes, N., Homola, V. C., Horandel, P., Horvath, J. R., Hrabovsky, P., Huber, M., Huege, D., Insolia, T., Ionita, A., Italiano, F., Jansen, A., Jarne, S., Jiraskova, C., Josebachuili, S., Kadija, M., Kampert, K., Karhan, K. H., Kasper, P., Katkov, P., Kegl, I., Keilhauer, B., Keivani, B., Kelley, A., Kemp, J. L., Kieckhafer, E., Klages, R. M., Kleifges, H. O., Kleinfeller, M., Knapp, J., Koang, J., Kotera, D. H., Krohm, K., Kromer, N., Kruppke Hansen, O., Kuempel, D., Kulbartz, D., Kunka, J. K., La Rosa, N., Lachaud, G., Lahurd, C., Latronico, D., Lauer, L., Lautridou, R., Le Coz, P., Leao, S., Lebrun, Msab and, Lebrun, D., de Oliveira, P., Letessier Selvon, M. A. L., Lhenry Yvon, A., Link, I., Lopez, K., Aguera, R., Louedec, A. L., Bahilo, K., J. L., Lu, Lucero, L., Ludwig, A., Lyberis, M., Maccarone, H., Macolino, M. C., Maldera, C., Maller, S., Mandat, J., Mantsch, D., Mariazzi, P., Marin, A. G., Marin, J., Maris, V., Falcon, I. C., Marsella, H. R. M., Martello, G., Martin, D., Martinez, L., Bravo, H., Martraire, O. M., Meza, D., Mathes, J. J. M., Matthews, H. J., Matthews, J., Matthiae, A. J., Maurel, G., Maurizio, D., Mazur, D., Medina Tanco, P. O., Melissas, G., Melo, M., Menichetti, D., Menshikov, E., Mertsch, A., Meurer, P., Meyhandan, C., Mi'Canovi'C, R., Micheletti, S., Minaya, M. I., Miramonti, I. A., Molina Bueno, L., Mollerach, L., Monasor, S., Ragaigne, M., Montanet, D. M., Morales, F., Morello, B., Moreno, C., Moreno, E., Mostafa, J. C., Moura, M., Muller, C. A., Muller, M. A., Munchmeyer, G., Mussa, M., Navarra, R., Navarro, G., Navas, J. L., Necesal, S., Nellen, P., Nelles, L., Neuser, A., Nhung, J., Niechciol, P. T., Niemietz, M., Nierstenhoefer, L., Nitz, N., Nosek, D., Nozka, D., Oehlschlager, L., Olinto, J., Ortiz, A., Pacheco, M., Selmi Dei, N., Palatka, D. P., Pallotta, M., Palmieri, J., Parente, N., Parizot, G., Parra, E., Pastor, A., Paul, S., Pech, T., Pekala, M., Pelayo, J., Pepe, R., Perrone, I. M., Pesce, L., Petermann, R., Petrera, E., Petrolini, Alessandro, Petrov, A., Pfendner, Y., Piegaia, C., Pierog, R., Pieroni, T., Pimenta, P., Pirronello, M., Platino, V., Plum, M., Ponce, M., Pontz, V. H., Porcelli, M., Privitera, A., Prouza, P., Quel, M., Querchfeld, E. J., Rautenberg, S., Ravel, J., Ravignani, O., Revenu, D., Ridky, B., Riggi, J., Risse, S., Ristori, M., Rivera, P., Rizi, H., Roberts, V., de Carvalho, J., Rodriguez, W. R., Cabo, G., Martino, I. R., Rojo, J. R., Rodriguez Frias, J. R., Ros, M. D., Rosado, G., Rossler, J., Roth, T., Rouille d'Orfeuil, M., Roulet, B., Rovero, E., Ruhle, A. C., Saftoiu, C., Salamida, A., Salazar, F., Greus, H., Salina, F. S., Sanchez, G., Santo, F., Santos, C. E., Santos, E., Sarazin, E. M., Sarkar, F., Sarkar, B., Sato, S., Scharf, R., Scherini, N., Schieler, V., Schiffer, H., Schmidt, P., Scholten, A., Schoorlemmer, O., Schovancova, H., Schovanek, J., Schroder, P., Schulte, F., Schuster, S., Sciutto, D., Scuderi, S. J., Segreto, M., Settimo, A., Shadkam, M., Shellard, A., Sidelnik, R. C., Sigl, I., Lopez, G., Sima, H. H. S., Smialkowski, O., Smida, A., Snow, R., Sommers, G. R., Sorokin, P., Spinka, J., Squartini, H., Srivastava, R., Stanic, Y. N., Stapleton, S., Stasielak, J., Stephan, J., Stutz, M., Suarez, A., Suomijarvi, F., Supanitsky, T., Susa, A. D., Sutherland, T., Swain, M. S., Szadkowski, J., Szuba, Z., Tapia, M., Tartare, A., Tascau, M., Tcaciuc, O., Thao, R., Thomas, N. T., Tiffenberg, D., Timmermans, J., Tkaczyk, C., Peixoto, W., Toma, C. J. T., Tomankova, G., Tome, L., Tonachini, B., Travnicek, A., Tridapalli, P., Tristram, D. B., Trovato, G., Tueros, E., Ulrich, M., Unger, R., Urban, M., Galicia, M., Valino, J. F. V., Valore, I., Van Aar, L., van den Berg, G., van Vliet, A. M., Varela, A., Cardenas, E., Vazquez, B. V., Vazquez, J. R., Veberic, R. A., Verzi, D., Vicha, V., Videla, J., Villasenor, M., Wahlberg, L., Wahrlich, H., Wainberg, P., Walz, O., Watson, D., Weber, A. A., Weidenhaupt, M., Weindl, K., Werner, A., Westerhoff, F., Whelan, S., Widom, B. J., Wieczorek, A., Wiencke, G., Wilczynska, L., Wilczynski, B., Will, H., Williams, M., Winchen, C., Wommer, T., Wundheiler, M., Yamamoto, B., Yapici, T., Younk, T., Yuan, P., Yushkov, G., Garcia, A., Zas, B. Z., Zavrtanik, E., Zavrtanik, D., Zaw, M., Zepeda, I., Zhou, A., Zhu, J., Silva, Y., Ziolkowski, M. Z., Pierre Auger, M., APC - Astrophysique des Hautes Energies (APC - AHE), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire SUBATECH Nantes (SUBATECH), Mines Nantes (Mines Nantes)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire d'Orsay (IPNO), PIERRE AUGER, P., Abreu, M., Aglietta, M., Ahler, E. J., Ahn, I. F. M., Albuquerque, D., Allard, I., Allekotte, J., Allen, P., Allison, A., Almela, J., Alvarez Castillo, J., Alvarez Muñiz, R., Alves Batista, M., Ambrosio, A., Aminaei, L., Anchordoqui, S., Andringa, T., Antičić, C., Aramo, E., Arganda, F., Arquero, H., Asorey, P., Assi, J., Aublin, M., Ave, M., Avenier, G., Avila, A. M., Badescu, M., Balzer, K. B., Barber, A. F., Barbosa, R., Bardenet, S. L. C., Barroso, B., Baughman f, J., Bäuml, C., Bau, J. J., Beatty, K. H., Becker, A., Bellétoile, J. A., Bellido, S., Benzvi, C., Berat, X., Bertou, P. L., Biermann, P., Billoir, F., Blanco, M., Blanco, C., Bleve, H., Blümer, M., Boháčová, D., Boncioli, C., Bonifazi, R., Bonino, N., Borodai, J., Brack, I., Brancu, P., Brogueira, W. C., Brown, R., Bruijn i, P., Buchholz, A., Bueno, L., Buroker, R. E., Burton, K. S., Caballero Mora, B., Caccianiga, L., Caramete, R., Caruso, A., Castellina, O., Catalano, G., Cataldi, L., Cazon, R., Cester, J., Chauvin, S. H., Cheng, A., Chiavassa, J. A., Chinellato, J., Chirinos Diaz, J., Chudoba, M., Cilmo, R. W., Clay, Cocciolo, Giuseppe, L., Collica, Coluccia, MARIA RITA, R., Conceição, F., Contrera, H., Cook, M. J., Cooper, J., Coppen, A., Cordier, S., Coutu, C. E., Covault, A., Creusot, A., Cri, J., Cronin, A., Curutiu, S., Dagoret Campagne, R., Dallier, B., Daniel, S., Dasso, K., Daumiller, B. R., Dawson, R. M., de Almeida, M., De Domenico, C., De Donato, S. J., de Jong, G., De La Vega, W. J. M., de Mello Junior, J. R. T., de Mello Neto, DE MITRI, Ivan, V., de Souza, K. D., de Vrie, L., del Peral, M., del Río, O., Deligny, H., Dembinski, N., Dhital, C., Di Giulio, M. L., Díaz Castro, P. N., Diep, F., Diogo, C., Dobrigkeit, W., Docter, J. C., D'Olivo, P. N., Dong, A., Dorofeev, J. C., dos Anjo, M. T., Dova, D., D'Urso, I., Dutan, J., Ebr, R., Engel, M., Erdmann, C. O., Escobar, J., Espadanal, A., Etchegoyen, P., Facal San Lui, H., Falcke, K., Fang, G., Farrar, A. C., Fauth, N., Fazzini, A. P., Ferguson, B., Fick, J. M., Figueira, A., Filevich, A., Filipčič, S., Fliescher, C. E., Fracchiolla, E. D., Fraenkel!, O., Fratu, U., Fröhlich, B., Fuch, R., Gaior, R. F., Gamarra, S., Gambetta, B., García, S. T., Garcia Roca, D., Garcia Gamez, D., Garcia Pinto, G., Garilli, A., Gascon Bravo, H., Gemmeke, P. L., Ghia, M., Giller, J., Gitto, H., Gla, M. S., Gold, G., Golup, F., Gomez Albarracin, M., Gómez Berisso, P. F., Gómez Vitale, P., Gonçalve, J. G., Gonzalez, B., Gookin, A., Gorgi, P., Gouffon, E., Grashorn, S., Grebe, N., Griffith, A. F., Grillo, Y., Guardincerri, F., Guarino, G. P., Guede, P., Hansen, D., Harari, T. A., Harrison, J. L., Harton, A., Haung, T., Hebbeker, D., Heck, A. E., Herve, C., Hojvat, N., Hollon, V. C., Holme, P., Homola, J. R., Hörandel, P., Horvath, M., Hrabovský, D., Huber, T., Huege, A., Insolia, F., Ionita, A., Italiano, S., Jansen, C., Jarne, S., Jiraskova, M., Josebachuili, K., Kadija, K. H., Kampert, P., Karhan, P., Kasper, I., Katkov, B., Kégl, B., Keilhauer, A., Keivani, J. L., Kelley, E., Kemp, R. M., Kieckhafer, H. O., Klage, M., Kleifge, J., Kleinfeller, J., Knapp, D. H., Koang, K., Kotera, N., Krohm, O., Krömer, D., Kruppke Hansen, D., Kuempel, J. K., Kulbartz, N., Kunka, G., La Rosa, C., Lachaud, D., Lahurd, L., Latronico, R., Lauer, P., Lautridou, S., Le Coz, M. S. A. B., Leão, D., Lebrun, P., Lebrun, M. A., Leigui de Oliveira, A., Letessier Selvon, I., Lhenry Yvon, K., Link, R., López, A., Lopez Agüera, K., Louedec, J., Lozano Bahilo, L., Lu, A., Lucero, M., Ludwig, H., Lyberi, M. C., Maccarone, C., Macolino, S., Maldera, J., Maller, D., Mandat, P., Mantsch, A. G., Mariazzi, J., Marin, V., Marin, I. C., Mari, H. R., Marquez Falcon, Marsella, Giovanni, Martello, Daniele, L., Martin, H., Martinez, O., Martínez Bravo, D., Martraire, J. J., Masías Meza, H. J., Mathe, J., Matthew, J. A. J., Matthew, G., Matthiae, D., Maurel, D., Maurizio, P. O., Mazur, G., Medina Tanco, M., Melissa, D., Melo, E., Menichetti, A., Menshikov, P., Mertsch, C., Meurer, R., Meyhandan, S., Mićanović, M. I., Micheletti, I. A., Minaya, L., Miramonti, L., Molina Bueno, S., Mollerach, M., Monasor, D., Monnier Ragaigne, F., Montanet, B., Morale, C., Morello, E., Moreno, J. C., Moreno, M., Mostafá, C. A., Moura, M. A., Muller, G., Müller, M., Münchmeyer, R., Mussa, G., Navarra ‡, J. L., Navarro, S., Nava, P., Necesal, L., Nellen, A., Nelle, J., Neuser, P. T., Nhung, M., Niechciol, L., Niemietz, N., Nierstenhoefer, D., Nitz, D., Nosek, L., Nožka, J., Oehlschläger, A., Olinto, M., Ortiz, N., Pacheco, D., Pakk Selmi Dei, M., Palatka, J., Pallotta, N., Palmieri, G., Parente, E., Parizot, A., Parra, S., Pastor, T., Paul, M., Pech, J., Pękala, R., Pelayo, I. M., Pepe, Perrone, Lorenzo, R., Pesce, E., Petermann, S., Petrera, A., Petrolini, Y., Petrov, C., Pfendner, R., Piegaia, T., Pierog, P., Pieroni, M., Pimenta, V., Pirronello, M., Platino, M., Plum, V. H., Ponce, M., Pontz, A., Porcelli, P., Privitera, M., Prouza, E. J., Quel, S., Querchfeld, J., Rautenberg, O., Ravel, D., Ravignani, B., Revenu, J., Ridky, S., Riggi, M., Risse, P., Ristori, H., Rivera, V., Rizi, J., Robert, W., Rodrigues de Carvalho, G., Rodriguez, I., Rodriguez Cabo, J., Rodriguez Martino, J., Rodriguez Rojo, M. D., Rodríguez Fría, G., Ro, J., Rosado, T., Rossler, M., Roth, B., Rouillé d'Orfeuil, E., Roulet, A. C., Rovero, C., Rühle, A., Saftoiu, F., Salamida, H., Salazar, F., Salesa Greu, G., Salina, F., SÃ! ¡nchez, C. E., Santo, E., Santo, E. M., Santo, F., Sarazin, B., Sarkar, S., Sarkar, R., Sato, N., Scharf, V., Scherini, H., Schieler, P., Schiffer, A., Schmidt, O., Scholten, H., Schoorlemmer, J., Schovancova, P., Schovánek, F., Schröder, S., Schulte, D., Schuster, S. J., Sciutto, M., Scuderi, A., Segreto, M., Settimo, A., Shadkam, R. C., Shellard, I., Sidelnik, G., Sigl, H. H., Silva Lopez, O., Sima, A., Śmiałkowski, R., Šmída, G. R., Snow, P., Sommer, J., Sorokin, H., Spinka, R., Squartini, Y. N., Srivastava, S., Stanic, J., Stapleton, J., Stasielak, M., Stephan, A., Stutz, F., Suarez, T., Suomijärvi, A. D., Supanitsky, T., Šuša, M. S., Sutherland, J., Swain, Z., Szadkowski, M., Szuba, A., Tapia, M., Tartare, O., Taşcău, R., Tcaciuc, N. T., Thao, D., Thoma, J., Tiffenberg, C., Timmerman, W., Tkaczyk, C. J., Todero Peixoto, G., Toma, L., Tomankova, B., Tomé, A., Tonachini, P., Travnicek, D. B., Tridapalli, G., Tristram, E., Trovato, M., Tuero, R., Ulrich, M., Unger, M., Urban, J. F., Valdés Galicia, I., Valiño, L., Valore, G., van Aar, A. M., van den Berg, A., van Vliet, E., Varela, B., Vargas Cárdena, J. R., Vázquez, R. A., Vázquez, D., Veberič, V., Verzi, J., Vicha, M., Videla, L., Villaseñor, H., Wahlberg, P., Wahrlich, O., Wainberg, D., Walz, A. A., Watson, M., Weber, K., Weidenhaupt, A., Weindl, F., Werner, S., Westerhoff, B. J., Whelan, A., Widom, G., Wieczorek, L., Wiencke, B., Wilczyńska, H., Wilczyński, M., Will, C., William, T., Winchen, M., Wommer, B., Wundheiler, T., Yamamoto a, T., Yapici, P., Younk, G., Yuan, A., Yushkov, B., Zamorano Garcia, E., Za, D., Zavrtanik, M., Zavrtanik, I., Zaw h, A., Zepeda b, J., Zhou, Y., Zhu, M., Zimbres Silva, M. Ziolkowski, ., P. Abreu, M. Aglietta, M. Ahler, E.J. Ahn, I.F.M. Albuquerque, D. Allard, I. Allekotte, J. Allen, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, R. Alves Batista, M. Ambrosio, A. Aminaei, L. Anchordoqui, S. Andringa, T. Antičić, C. Aramo, E. Arganda, F. Arquero, H. Asorey, P. Assi, J. Aublin, M. Ave, M. Avenier, G. Avila, A.M. Badescu, M. Balzer, K.B. Barber, A.F. Barbosa, R. Bardenet, S.L.C. Barroso, B. Baughman f, J. Bäuml, C. Bau, J.J. Beatty, K.H. Becker, A. Bellétoile, J.A. Bellido, S. BenZvi, C. Berat, X. Bertou, P.L. Biermann, P. Billoir, F. Blanco, M. Blanco, C. Bleve, H. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, R. Bonino, N. Borodai, J. Brack, I. Brancu, P. Brogueira, W.C. Brown, R. Bruijn i, P. Buchholz, A. Bueno, L. Buroker, R.E. Burton, K.S. Caballero-Mora, B. Caccianiga, L. Caramete, R. Caruso, A. Castellina, O. Catalano, G. Cataldi, L. Cazon, R. Cester, J. Chauvin, S.H. Cheng, A. Chiavassa, J.A. Chinellato, J. Chirinos Diaz, J. Chudoba, M. Cilmo, R.W. Clay, G. Cocciolo, L. Collica, M.R. Coluccia, R. Conceição, F. Contrera, H. Cook, M.J. Cooper, J. Coppen, A. Cordier, S. Coutu, C.E. Covault, A. Creusot, A. Cri, J. Cronin, A. Curutiu, S. Dagoret-Campagne, R. Dallier, B. Daniel, S. Dasso, K. Daumiller, B.R. Dawson, R.M. de Almeida, M. De Domenico, C. De Donato, S.J. de Jong, G. De La Vega, W.J.M. de Mello Junior, J.R.T. de Mello Neto, I. De Mitri, V. de Souza, K.D. de Vrie, L. del Peral, M. del Río, O. Deligny, H. Dembinski, N. Dhital, C. Di Giulio, M.L. Díaz Castro, P.N. Diep, F. Diogo, C. Dobrigkeit, W. Docter, J.C. D'Olivo, P.N. Dong, A. Dorofeev, J.C. dos Anjo, M.T. Dova, D. 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Meurer, R. Meyhandan, S. Mićanović, M.I. Micheletti, I.A. Minaya, L. Miramonti, L. Molina-Bueno, S. Mollerach, M. Monasor, D. Monnier Ragaigne, F. Montanet, B. Morale, C. Morello, E. Moreno, J.C. Moreno, M. Mostafá, C.A. Moura, M.A. Muller, G. Müller, M. Münchmeyer, R. Mussa, G. Navarra ‡, J.L. Navarro, S. Nava, P. Necesal, L. Nellen, A. Nelle, J. Neuser, P.T. Nhung, M. Niechciol, L. Niemietz, N. Nierstenhoefer, D. Nitz, D. Nosek, L. Nožka, J. Oehlschläger, A. Olinto, M. Ortiz, N. Pacheco, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, N. Palmieri, G. Parente, E. Parizot, A. Parra, S. Pastor, T. Paul, M. Pech, J. Pękala, R. Pelayo, I.M. Pepe, L. Perrone, R. Pesce, E. Petermann, S. Petrera, A. Petrolini, Y. Petrov, C. Pfendner, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, V.H. Ponce, M. Pontz, A. Porcelli, P. Privitera, M. Prouza, E.J. Quel, S. Querchfeld, J. Rautenberg, O. Ravel, D. Ravignani, B. Revenu, J. Ridky, S. Riggi, M. Risse, P. Ristori, H. 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Ziolkowski ., Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Dipartimento di Astronomia, Universita degli Studi di Bologna, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO)-Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Nantes (UN)-Mines Nantes (Mines Nantes), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Aramo, Carla, D'Urso, Domenico, Guarino, Fausto, Valore, Laura, The Pierre Auger, Collaboration, KVI - Center for Advanced Radiation Technology, Research unit Astroparticle Physics, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Dipartimento di Astronomia, Universita degli Studi di Bologna, Università di Bologna [Bologna] (UNIBO)-Università di Bologna [Bologna] (UNIBO), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), and PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)

Subjects
[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Astronomy, FOS: Physical sciences, Cosmic ray, Real-time monitoring, 01 natural sciences, Large detector systems for particle and astroparticle physics, Real-time monitoring, Control and monitor systems online, Optical telescope, Observatory, 0103 physical sciences, SHOWERS, Large detector systems for particle and astroparticle physics, Control and monitor systems online, FLUORESCENCE, 010303 astronomy & astrophysics, Instrumentation, Instrumentation and Methods for Astrophysics (astro-ph.IM), DETECTOR, Mathematical Physics, Remote sensing, Event reconstruction, Pierre Auger Observatory, High Energy Astrophysical Phenomena (astro-ph.HE), 010308 nuclear & particles physics, [SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Física, ENERGY-SPECTRUM, Monitoring program, Aerosol, ATMOSFERA (MONITORAMENTO), Air shower, Experimental High Energy Physics, Física nuclear, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The Pierre Auger Observatory is a facility built to detect air showers produced by cosmic rays above 1017 eV. During clear nights with a low illuminated moon fraction, the UV fluorescence light produced by air showers is recorded by optical telescopes at the Observatory. To correct the observations for variations in atmospheric conditions, atmospheric monitoring is performed at regular intervals ranging from several minutes (for cloud identification) to several hours (for aerosol conditions) to several days (for vertical profiles of temperature, pressure, and humidity). In 2009, the monitoring program was upgraded to allow for additional targeted measurements of atmospheric conditions shortly after the detection of air showers of special interest, e. g., showers produced by very high-energy cosmic rays or showers with atypical longitudinal profiles. The former events are of particular importance for the determination of the energy scale of the Observatory, and the latter are characteristic of unusual air shower physics or exotic primary particle types. The purpose of targeted (or "rapid") monitoring is to improve the resolution of the atmospheric measurements for such events. In this paper, we report on the implementation of the rapid monitoring program and its current status. The rapid monitoring data have been analyzed and applied to the reconstruction of air showers of high interest, and indicate that the air fluorescence measurements affected by clouds and aerosols are effectively corrected using measurements from the regular atmospheric monitoring program. We find that the rapid monitoring program has potential for supporting dedicated physics analyses beyond the standard event reconstruction.

Published
2012
Full Text
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15. Poster session II * Thursday 9 December 2010, 14:00-18:00

Author

Pabari, P. A., primary, Kyriacou, A., additional, Moraldo, M., additional, Unsworth, B., additional, Baruah, R., additional, Sutaria, N., additional, Hughes, A., additional, Mayet, J., additional, Francis, D. P., additional, Uejima, T., additional, Loboz, K., additional, Antonini-Canterin, F., additional, Polombo, C., additional, Carerj, S., additional, Vinereanu, D., additional, Evangelista, A., additional, Leftheriotis, G., additional, Fraser, A. G., additional, Kiotsekoglou, A., additional, Govindan, M., additional, Govind, S. C., additional, Saha, S. K., additional, Camm, A. J., additional, Azcarate, P. M., additional, Castano, S., additional, Rodriguez-Manero, M., additional, Arraiza, M., additional, Levy, B., additional, Barba, J., additional, Rabago, G., additional, Bastarrika, G., additional, Nemes, A., additional, Takacs, R., additional, Varkonyi, T., additional, Gavaller, H., additional, Baczko, I., additional, Forster, T., additional, Wittmann, T., additional, Papp, J. G., additional, Lengyel, C., additional, Varro, A., additional, Tumasyan, L. R., additional, Adamyan, K. G., additional, Savu, O., additional, Mieghem, T., additional, Dekoninck, P., additional, Gucciardo, L., additional, Jurcut, R., additional, Giusca, S., additional, Popescu, B. A., additional, Ginghina, C., additional, Deprest, J., additional, Voigt, J. U., additional, Versiero, M., additional, Galderisi, M., additional, Esposito, R., additional, Rapacciuolo, A., additional, Esposito, G., additional, Raia, R., additional, Morgillo, T., additional, Piscione, F., additional, De Simone, G., additional, Oraby, M. A., additional, Maklady, F. A., additional, Mohamed, E. M., additional, Eraki, A. Z., additional, Zaliaduonyte-Peksiene, D., additional, Tamuleviciute, E., additional, Janenaite, J., additional, Marcinkeviciene, J., additional, Mizariene, V., additional, Bucyte, S., additional, Vaskelyte, J., additional, Trifunovic, D., additional, Nedeljkovic, I., additional, Popovic, D., additional, Ostojic, M., additional, Vujisic-Tesic, B., additional, Petrovic, M., additional, Stankovic, S., additional, Sobic-Saranovic, D., additional, Banovic, M., additional, Dikic-Djordjevic, A., additional, Savino, K., additional, Lilli, A., additional, Grikstaite, E., additional, Giglio, V., additional, Bordoni, E., additional, Maragoni, G., additional, Cavallini, C., additional, Ambrosio, G., additional, Jakovljevic, B., additional, Beleslin, B., additional, Nedeljkovic, M., additional, Petrovic, O., additional, Moral, S., additional, Rodriguez-Palomares, J., additional, Descalzo, M., additional, Marti, G., additional, Pineda, V., additional, Mahia, P., additional, Gutierrez, L., additional, Gonzalez-Alujas, T., additional, Garcia-Dorado, D., additional, Schnell, F., additional, Donal, E., additional, Thebault, C., additional, Bernard, A., additional, Corbineau, H., additional, Le Breton, H., additional, Kochanowski, J., additional, Scislo, P., additional, Piatkowski, R., additional, Roik, M., additional, Marchel, M., additional, Kosior, D., additional, Opolski, G., additional, Lesniak-Sobelga, A. 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M., additional, Faber, L., additional, Scholtz, W., additional, Boergermann, J., additional, Wiemer, M., additional, Kleikamp, G., additional, Bogunovic, N., additional, Dimitriadis, Z., additional, Gummert, J., additional, Hering, D., additional, Horstkotte, D., additional, Luca', F., additional, Gelsomino, S., additional, Lorusso, R., additional, Caciolli, S., additional, Carella, R., additional, Bille', G., additional, De Cicco, G., additional, Pazzagli, V., additional, Gensini, G. F., additional, Borowiec, A., additional, Dabrowski, R., additional, Janas, J., additional, Kraska, A., additional, Firek, B., additional, Kowalik, I., additional, Szwed, H., additional, Marcus, K. A., additional, De Korte, C. L., additional, Feuth, T., additional, Thijssen, J. M., additional, Kapusta, L., additional, Dahl, J., additional, Videbaek, L., additional, Poulsen, M. K., additional, Pellikka, P. A., additional, Veien, K., additional, Andersen, L. 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J., additional, Ferrer Sistach, E., additional, Delgado, L., additional, Lopez Ayerbe, J., additional, Vallejo Camazon, N., additional, Gual Capllonch, F., additional, Espriu Simon, M., additional, Ruyra, X., additional, Caballero Parrilla, A., additional, Bayes Genis, A., additional, Lecuyer, L., additional, Berrebi, A., additional, Florens, E., additional, Noghin, M., additional, Huerre, C., additional, Achouh, P., additional, Zegdi, R., additional, Fabiani, J. N., additional, De Chiara, B., additional, Moreo, A., additional, Musca, F., additional, De Marco, F., additional, Lobiati, E., additional, Belli, O., additional, Mauri, F., additional, Klugmann, S., additional, Caballero, A., additional, Vallejo, N., additional, Gonzalez Guardia, A., additional, Nunez Aragon, R., additional, Bosch, C., additional, Ferrer, E., additional, Pedro Botet, M. L., additional, Gual, F., additional, Cusma-Piccione, M., additional, Zito, C., additional, Oreto, G., additional, Giuffre, R., additional, Todaro, M. C., additional, Barbaro, C. M., additional, Lanteri, S., additional, Longordo, C., additional, Salvia, J., additional, Bensaid, A., additional, Gallet, R., additional, Fougeres, E., additional, Lim, P., additional, Nahum, J., additional, Deux, J. F., additional, Gueret, P., additional, Teiger, E., additional, Dubois-Rande, J. L., additional, Monin, J. L., additional, Behramoglu, F., additional, Colakoglu, Z., additional, Aytekin, V., additional, Demiroglu, C., additional, Gargani, L., additional, Poggianti, E., additional, Bucalo, R., additional, Rizzo, M., additional, Agrusta, F., additional, Landi, P., additional, Sicari, R., additional, Picano, E., additional, Sutandar, A., additional, Siswanto, B. B., additional, Irmalita, I., additional, Harimurti, G., additional, Hayashi, S. Y., additional, Nascimento, M. M., additional, Lindholm, B., additional, Lind, B., additional, Seeberger, A., additional, Pachaly, M. A., additional, Riella, M. C., additional, Bjallmark, A., additional, Brodin, L. A., additional, Poanta, L., additional, Porojan, M., additional, Dumitrascu, D. L., additional, Ikonomidis, I., additional, Tzortzis, S., additional, Lekakis, J., additional, Kremastinos, D. T., additional, Paraskevaidis, I., additional, Andreadou, I., additional, Nikolaou, M., additional, Katsibri, P., additional, Anastasiou-Nana, M., additional, Maceira Gonzalez, A. M., additional, Ripoll, C., additional, Cosin-Sales, J., additional, Igual, B., additional, Salazar, J., additional, Belloch, V., additional, Cosin-Aguilar, J., additional, Pennell, D. J., additional, Masaki, M., additional, Pulido, J. N., additional, Yuasa, T., additional, Gillespie, S., additional, Afessa, B., additional, Brown, D. R., additional, Mankad, S. V., additional, Oh, J. K., additional, Gurghean, A. L., additional, Mihailescu, A. M., additional, Tudor, I., additional, Homentcovschi, C., additional, Muraru, M., additional, Bruckner, I. V., additional, Correia, C. E., additional, Rodrigues, B., additional, Moreira, D., additional, Santos, L. 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S., additional, Gaspar, P., additional, Lourenco, A., additional, Medeiros, R., additional, Almeida, J., additional, L Bennani, S., additional, Algalarrondo, V., additional, Dinanian, S., additional, Guiader, J., additional, Juin, C., additional, Adams, D., additional, Slama, M. S., additional, Onaindia, J. J., additional, Quintana, O., additional, Velasco, S., additional, Astigarraga, E., additional, Cacicedo, A., additional, Gonzalez, J., additional, Rodriguez, I., additional, Sadaba, M., additional, Eneriz, M., additional, Laraudogoitia Zaldumbide, E., additional, Nunez-Gil, I., additional, Luaces, M., additional, Zamorano, J., additional, Garcia Rubira, J. C., additional, Vivas, D., additional, Ibanez, B., additional, Marcos Alberca, P., additional, Fernandez Golfin, C., additional, Alonso, J., additional, Macaya, C., additional, Silva Marques, J., additional, Almeida, A. G., additional, Carvalho, V., additional, Jorge, C., additional, Silva, D., additional, Gato Varela, M., additional, Martins, S., additional, Brito, D., additional, Lopes, M. G., additional, Tripodi, E., additional, Miserrafiti, B., additional, Montemurro, V., additional, Scali, R., additional, Tripodi, P., additional, Winkler, A., additional, Madej, A., additional, Hausmanowa-Petrusewicz, I., additional, Fijalkowski, M., additional, Koprowski, A., additional, Jaguszewski, M., additional, Galaska, R., additional, Taszner, M., additional, Rynkiewicz, A., additional, Citro, R., additional, Rigo, F., additional, Provenza, G., additional, Ciampi, Q., additional, Patella, M. M., additional, D'andrea, A., additional, Vriz, O., additional, Astarita, C., additional, Bossone, E., additional, Heggemann, F., additional, Walter, T. H., additional, Kaelsch, T. H., additional, Sueselbeck, T., additional, Papavassiliu, T. H., additional, Borggrefe, M., additional, Haghi, D., additional, Monk-Hansen, T., additional, Have Dall, C., additional, Bisgaard Christensen, S., additional, Snoer, M., additional, Gustafsson, F., additional, Rasmusen, H., additional, Prescott, E., additional, Finocchiaro, G., additional, Pinamonti, B., additional, Merlo, M., additional, Barbati, G., additional, Di Lenarda, A., additional, Bussani, R., additional, Sinagra, G., additional, Butz, T., additional, Lang, C. N., additional, Meissner, A., additional, Plehn, G., additional, Yeni, H., additional, Langer, C., additional, Trappe, H. J., additional, Gu, X., additional, Gu, X. Y., additional, He, Y. H., additional, Li, Z. A., additional, Han, J. 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M., additional, Rosca, M., additional, O' Connor, K., additional, Romano, G., additional, Magne, J., additional, Calin, A., additional, Muraru, D., additional, Pierard, L., additional, Lancellotti, P., additional, Roushdy, A., additional, Elfiky, I., additional, El Shahid, G., additional, Elfiky, A., additional, El Sayed, M., additional, Wierzbowska-Drabik, K., additional, Chrzanowski, L., additional, Kapusta, A., additional, Plonska-Goscinak, E., additional, Krzeminska-Pakula, M., additional, Kurpesa, M., additional, Rechcinski, T., additional, Trzos, E., additional, Kasprzak, J. D., additional, Ersboll, M. K., additional, Valeur, N., additional, Mogensen, U. M., additional, Andersen, M., additional, Hassager, C., additional, Sogaard, P., additional, Kober, L. V., additional, Kloeckner, M., additional, Hayat, D., additional, Dussault, C., additional, Lellouche, N., additional, Elbaz, N., additional, Demopoulos, A., additional, Hatzigeorgiou, G., additional, Leontiades, E., additional, Motsi, A., additional, Karatasakis, G., additional, Athanassopoulos, G., additional, Zycinski, P., additional, Kasprzak, J., additional, Vazquez Alvarez, M. C., additional, Medrano Lopez, C., additional, Camino Lopez, M., additional, Granja, S., additional, Zunzunegui Martinez, J. L., additional, Maroto Alvaro, E., additional, Tsai, W.-C., additional, Chen, J.-Y., additional, Liu, Y.-W., additional, Lin, C.-C., additional, Tsai, L.-M., additional, Gomes, D. C., additional, Robalo Martins, S., additional, Gois, M. R., additional, Ribeiro, S., additional, Nunes Diogo, A., additional, Sengupta, P., additional, Di Bella, G., additional, Caracciolo, G., additional, Lentini, S., additional, Kinova, E., additional, Zlatareva, N., additional, Goudev, A., additional, Papagiannis, N., additional, Mpouki, M., additional, Papagianni, A., additional, Vorria, M., additional, Mpenetos, G., additional, Lytra, D., additional, Papadopoulou, E., additional, Sgourakis, P., additional, Malakos, J., additional, Kyriazis, J., additional, Kodali, V., additional, Toole, R., additional, Gopal, A. S., additional, Celutkiene, J., additional, Rudys, A., additional, Grabauskiene, V., additional, Glaveckaite, S., additional, Sadauskiene, E., additional, Lileikiene, Z., additional, Bickauskaite, N., additional, Ciburiene, E., additional, Skorniakov, V., additional, Laucevicius, A., additional, Attenhofer Jost, C. H., additional, Pfyffer, M., additional, Lindquist, R., additional, Santos, J. L. F., additional, Coelho, O. R. C., additional, Mady, C. M., additional, Picard, M. H. P., additional, Salemi, V. M. C., additional, Funk, L., additional, Prull, M. W., additional, Shih, J.-Y., additional, Huang, Y.-Y., additional, O'connor, K., additional, Moonen, M., additional, Pierard, L. A., additional, Cozma, D. C., additional, Mornos, C., additional, Ionac, A., additional, Petrescu, L., additional, Dragulescu, D., additional, Dan, R., additional, Popescu, I., additional, Dragulescu, S. I., additional, Von Lueder, T. G., additional, Hodt, A., additional, Gjerdalen, G. F., additional, Andersen, T. E., additional, Solberg, E. E., additional, Steine, K., additional, Van Mieghem, T., additional, Rostek, M., additional, Pikto-Pietkiewicz, W., additional, Dluzniewski, M., additional, Antoniewicz, A., additional, Poletajew, S., additional, Borowka, A., additional, Pasierski, T., additional, Malyutina, S. K., additional, Ryabikov, M., additional, Ragino, J., additional, Ryabikov, A., additional, Sitia, S., additional, Tomasoni, L., additional, Atzeni, F., additional, Gianturco, L., additional, Sarzi-Puttini, P., additional, De Gennaro Colonna, V., additional, Turiel, M., additional, Gutierrez, F. R., additional, Lefhtheriotis, G., additional, Hurst, R. T., additional, Nelson, M. R., additional, Mookadam, F., additional, Thota, V., additional, Emani, U., additional, Al Harthi, M., additional, Stepanek, J., additional, Cha, S., additional, Lester, S. J., additional, Ho, E. M. M., additional, Hemeryck, L., additional, Hall, M., additional, Scott, K., additional, Bennett, K., additional, Mahmud, A., additional, Daly, C., additional, King, G., additional, Murphy, R. T., additional, Brown, A. S., additional, Teske, A. J., additional, D'Hooge, J., additional, Claus, P., additional, Rademakers, F., additional, Santos, L., additional, Cortez-Dias, N., additional, Goncalves, S., additional, Almeida Ribeiro, M., additional, Bordalo E Sa, A., additional, Magnino, C., additional, Marcos-Alberca, P., additional, Milan, A., additional, Almeria, C., additional, Caniadas, V., additional, Rodrigo, J. L., additional, Perez De Isla, L., additional, Zamorano, J. L., additional, Gustafsson, U., additional, Larsson, M., additional, Lindqvist, P., additional, Brodin, L., additional, Waldenstrom, A., additional, Roosens, B., additional, Hernot, S., additional, Droogmans, S., additional, Van Camp, G., additional, Lahoutte, T., additional, Cosyns, B., additional, Rao, C. M., additional, Aguglia, D., additional, Casciola, G., additional, Imbesi, C., additional, Marvelli, A., additional, Sgro, M., additional, Benedetto, D., additional, Tripepi, R., additional, Zoccali, C., additional, Benedetto, F. A., additional, Badano, L. P., additional, Cardillo, M., additional, Del Mestre, L., additional, Gianfagna, P., additional, Proclemer, A., additional, Tschernich, H. D., additional, Mora, B., additional, Base, E., additional, Weber, U., additional, Dumfarth, J., additional, Mukherjee, C., additional, Skaltsiotis, H. S., additional, Kaladaridis, A. K., additional, Bramos, D. B., additional, Kottis, G. K., additional, Antoniou, A. A., additional, Agrios, I. A., additional, Takos, D. T., additional, Vasiladiotis, N. V., additional, Pamboucas, K. P., additional, Toumanidis, S. T. T., additional, Shim, A., additional, Lipec, P., additional, Michalski, B., additional, Wozniakowski, B., additional, Stefanczyk, L., additional, Rotkiewicz, A., additional, Cameli, M., additional, Lisi, M., additional, Padeletti, M., additional, Bigio, E., additional, Bernazzali, S., additional, Tsoulpas, C., additional, Maccherini, M., additional, Henein, M., additional, Mondillo, S., additional, Garcia Lunar, I., additional, Mingo Santos, S., additional, Monivas Palomero, V., additional, Mitroi, C., additional, Beltran Correas, P., additional, Ruiz Bautista, L., additional, Muniz Lozano, A., additional, Gonzalez Gonzalez, M., additional, Pabari, P. A., additional, Stegemann, B., additional, Willson, K., additional, Zeppellini, R., additional, Iavernaro, A., additional, Zadro, M., additional, Carasi, M., additional, De Domenico, R., additional, Rigo, T., additional, Artuso, E., additional, Erente, G., additional, Ramondo, A., additional, Le, T. T., additional, Huang, F. Q., additional, Gu, Y., additional, and Tan, R. S., additional

Published
2010
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16. 105 PCA3: A MULTICENTER EXPERIENCE FROM SOUTHERN ITALY

Author

Autorino, R., primary, Damiano, R., additional, De Sio, M., additional, Pizzuti, M., additional, Muscariello, R., additional, De Domenico, R., additional, Quarto, G., additional, Azzarito, G., additional, Gallo, L., additional, Gallo, A., additional, D' Armiento, M., additional, Di Lorenzo, G., additional, and Perdona, S., additional

Published
2010
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18. Ochratoxin A in cereal-based baby foods: occurrence and safety evaluation.

Author

Beretta, B., De Domenico, R., Gaiaschi, A., Ballabio, C., Galli, C. L., Gigliotti, C., and Restani, P.

Subjects
*CEREALS as food, *BABY foods, *OCHRATOXINS
Abstract

Ochratoxin A is a typical cereal contaminant with strong nephrotoxic activity. To estimate the quantity of ochratoxin A that can be taken in by a child in the weaning period, several samples of cereal-based baby foods were analysed. Although most samples analysed contained ochratoxin A in undetectable amounts or below the Italian legal limit of 0.5 μg kg[sub -1], some irregular products were found. In particular, the analyses of the 119 batches (338 samples) of baby foods considered indicated that: 20 batches (16.8%) contained detectable quantities of ochratoxin A and four of these (3.4% of the total) contained ochratoxin A above the Italian permitted value. All samples coming from agricultural practices based on integrated pest management contained undetectable amounts of ochratoxin A, while ∼5% of batches coming from conventional and organic agricultural practices were above the legal limit. On the basis of the established provisional tolerable weekly intake (PTWI), there is no significant toxicological risk for a child who occasionally consumes a formula with ochratoxin concentration slightly above the permitted level. However, stricter controls have to be applied to reject the batches containing irregular concentrations of ochratoxin A. [ABSTRACT FROM AUTHOR]

Published
2002
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20. PROFILI SISMICI PROFONDI IN SICILIA NORD-ORIENTALE (1986)

Author

Bottari, A, Balia, R, Caccamo, Domenico, Carapezza, E, Carrozzo, M. T., Colella, P, Cosentino, M, Cosentino, P, DE DOMENICO, R, Fais, S, Fradella, P, GAGLIANO CANDELA, E, Guerra, I, Luzio, D, Lombardo, G, Margiotta, C, Marino, A, Quarta, T, and Ranieri, G.

Published
1987

21. Prophylactic risk-reducing salpingo-oophorectomy in BRCA mutation carriers: what is going on in a region of northern Italy?

Author

M. Stefanetti, Fabio Facchinetti, Giovanni Grandi, Roberto Berretta, Laura Cortesi, Ruby Martinello, Angela Toss, P. De Iaco, A. Perrone, R. De Domenico, Andrea Amadori, Lorenzo Aguzzoli, Vincenzo Dario Mandato, Stefano Friso, C. Merisio, G Comerci, Pantaleo Greco, Gennaro Scutiero, Anna Myriam Perrone, F. Rosati, M. D. Nuzzo, V. Arcangeli, Margaret Sammarini, Grandi G., Perrone A.M., Perrone A., Mandato V.D., Comerci G., Sammarini M., Merisio C., Amadori A., Stefanetti M., Martinello R., Facchinetti F., De Iaco P., Aguzzoli L., Arcangeli V., Berretta R., Cortesi L., De Domenico R., Nuzzo M.D., Friso S., Greco P., Rosati F., Scutiero G., and Toss A.

Subjects
endocrine system diseases, medicine.medical_treatment, BRCA, 0302 clinical medicine, Medicine, 030212 general & internal medicine, Young adult, skin and connective tissue diseases, Ovarian Neoplasms, 030219 obstetrics & reproductive medicine, Obstetrics, BRCA1 Protein, Obstetrics and Gynecology, Middle Aged, female genital diseases and pregnancy complications, Risk-reducing salpingo-oophorectomy, Serous fluid, Italy, Female, Breast cancer survivor, Hysterectomy, Ovarian cancer, Prophylactic, pathology, Adult, Aged, BRCA2 Protein, Breast Neoplasms, Humans, Mutation, Risk, Young Adult, Salpingo-oophorectomy, Breast Neoplasm, Human, medicine.medical_specialty, Prophylactic, General Biochemistry, Genetics and Molecular Biology, NO, 03 medical and health sciences, Breast cancer, business.industry, Ovarian Neoplasm, BRCA mutation, Cancer, medicine.disease, Concomitant, pathology, business
Abstract

Background BRCA1 mutation carriers are recommended to undergo prophylactic risk-reducing salpingo-oophorectomy (RRSO) between the ages of 35 and 40 or when child bearing is complete, with a possible delay until age 40–45 for BRCA2 mutation carriers. Study Question Primary outcome was the rate of unsuspected cancer findings during RRSO in a region of northern Italy (Emilia Romagna) and secondary outcomes were details of RRSO: age at surgical intervention, the venue of the procedures in relation to the surgical/pathological quality and the rate/role of concomitant opportunistic hysterectomies. Study Design Multicentre data collection by invitation to report current RRSO practices. Results A total of 222 RRSOs (54.5 % BRCA1, 34.7 % BRCA2, 1.8 % BRCA1 and BRCA2 combined, 5.8 % BRCA-VUS and 3.2 % BRCA not better specified) were reported from 9 different centres, half in non-university hospitals and the remainder in university hospitals. Breast cancer survivors (56.3 %) underwent the RRSO at a younger age (47.8 vs 50.6 years, p = 0.02). The mean and median ages at surgical intervention (49.0 and 48.0, respectively) were similar for BRCA1 and BRCA2 mutation carriers, as was the temporal trend in age distribution, and proportions treated in university and non-university hospitals. A diagnosis of ovarian invasive cancer was reported in 3.5 % of subjects, all BRCA1 or BRCA-combined subjects, at a median and mean age of 57 years (range 42–68). Abnormal tubal findings, such as serous tubal intraepithelial lesions (STIL) (100 %), secretory cell outgrowth (SCOUT) (100 %) and STIC (71.4 %), were mainly reported by pathologists in university hospitals. Of the 222 procedures, 15 (6.7 %) included hysterectomies: in none of these cases was a primitive uterine endometrioid or serous cancer found. Conclusions The results from this multicentre regional study should guide future preventive health policies for RRSO in BRCA mutation carriers.

Published
2021

22. Visceral obesity predicts adverse pathological features in urothelial bladder cancer patients undergoing radical cystectomy: a retrospective cohort study

Author

Andrea Salonia, Alberto Briganti, Antonio Cicione, Rocco Damiano, Renato De Domenico, Riccardo Autorino, Francesco Cantiello, Matteo Ferro, S. Perdonà, Cantiello, F, Cicione, A, Autorino, Riccardo, Salonia, A, Briganti, A, Ferro, M, De Domenico, R, Perdonà, S, Damiano, R., Cantiello, Francesco, Cicione, Antonio, Salonia, Andrea, Briganti, Alberto, Ferro, Matteo, De Domenico, Renato, Perdona, Sisto, and Damiano, Rocco

Subjects
Male, medicine.medical_treatment, Pathological feature, Cohort Studies, Risk Factors, Retrospective Studie, Multivariate Analysi, Metabolic Syndrome, Bladder cancer, Lymph Node, Middle Aged, Prognosis, Obesity, Abdominal, Urinary Bladder Neoplasm, Female, Human, Cohort study, medicine.medical_specialty, Logistic Model, Pelvi, Prognosi, Urology, Urinary Bladder, Cystectomy, Pelvis, medicine, Humans, Neoplasm Invasiveness, Obesity, Risk factor, Pathological, Retrospective Studies, Aged, Neoplasm Staging, Neoplasm Invasivene, Carcinoma, Transitional Cell, business.industry, Risk Factor, Muscle, Smooth, Retrospective cohort study, medicine.disease, Logistic Models, Urinary Bladder Neoplasms, Multivariate Analysis, Lymph Node Excision, Lymph Nodes, Cohort Studie, Metabolic syndrome, business, Body mass index
Abstract

Purpose: To evaluate the pathological characteristics of patients with metabolic syndrome (MetS) undergoing radical cystectomy (RC) for urothelial bladder cancer (BCa). Methods: We retrospectively analyzed 262 consecutive patients with muscle-invasive urothelial BCa or non-muscle-invasive urothelial BCa bacillus Calmette-Guerin refractory undergoing RC with standard pelvic lymphadenectomy. The patients were stratified into those with or without MetS, and a bivariate logistic regression analysis was done to assess MetS and, separately, each single MetS component as independent predictors of higher pathological stage as well as of the presence of lymph vascular invasion (LVI) and lymph node metastasis (LM). Results: Metabolic syndrome was found in 36.3 % of patients. At logistic regression analysis, the presence of MetS did not predict the risk of both higher pathological stage and LVI and LM. Investigating the single components of MetS after adjusting for age, gender, and smoking, the risk of higher pathological stage increased with body mass index [BMI (OR 1.307, 95 % CI 1.098-1.555)], waist circumference (OR 1.414, 95 % CI 1.364-1.668), and blood hypertension (OR 2.326, 95 % CI 1.147-4.717). Higher BMI also predicted the presence of LVI (OR 1.432, 95 % CI 1.173-1.748) and LM (OR 1.202, 95 % CI 0.951-1.519), whereas HDL cholesterol was inversely associated with the risk of LVI and LM. Conclusions: Metabolic syndrome does not represent an independent risk factor for worse pathological findings in BCa. Conversely, individual components of MetS could increase the risk of higher stage as well as LM. © 2013 Springer-Verlag Berlin Heidelberg.

Published
2014

23. A new transportable shock-wave lithotripsy machine for managing urinary stones: a single-centre experience with a dual-focus lithotripter

Author

Marco De Sio, Riccardo Autorino, Giuseppe Quarto, Massimo D’Armiento, Ferdinando Di Giacomo, Carmelo Quattrone, Francesco Giugliano, D. Sorrentino, Salvatore Mordente, Fabio Neri, Renato De Domenico, DE SIO, Marco, Autorino, Riccardo, Quarto, G, Mordente, S, Giugliano, F, DI GIACOMO, F, Neri, F, Quattrone, C, Sorrentino, D, DE DOMENICO, R, and D'Armiento, M.

Subjects
Male, Nephrology, medicine.medical_specialty, Ureteral Calculi, Visual analogue scale, Urology, Urinary system, medicine.medical_treatment, Shock wave lithotripsy, Lithotripsy, Kidney Calculi, Risk Factors, Internal medicine, medicine, Humans, Prospective Studies, Prospective cohort study, Dual focus, business.industry, Equipment Design, Middle Aged, Extracorporeal shock wave lithotripsy, Surgery, Treatment Outcome, Female, business
Abstract

OBJECTIVE To assess the efficacy and safety of a transportable extracorporeal shock wave lithotripsy (ESWL) machine, the Modulith SLX-F2TM (Storz Medical Italia, Rome, Italy), in the management of solitary urinary calculi. PATIENTS AND METHODS The study included 233 patients (mean age 51 years; 172 male, 61 female) with symptomatic solitary renal (group A, 170, mean diameter 15.5 mm) or ureteric stones (group B, 63, mean diameter 9.5 mm) treated in a tertiary care institution. Exclusion criteria for the analysis were: pelvi-ureteric junction obstruction, multiple stones, stone diameter >2 cm, stones in a lower calyx with unfavourable anatomy, active infection, or impacted ureteric stones. Selected patients had ureteric stenting before treatment, and all patients were treated with no anaesthesia. Hospitalization, complications and subsequent auxiliary procedures were evaluated. Patients were assessed after a single ESWL session and after 3 months by a plain abdominal film and renal ultrasonography. Stone-free status was defined as no evidence of calculi, and clinical success as the presence of stone fragments of 1 cm were statistically significant (P

Published
2007

25. Nurses' perception of the oncology patient's death: a qualitative study.

Author

Gambalunga F, Taraborelli E, De Domenico R, Di Muzio M, Notarnicola I, Latina R, and Iacorossi L

Subjects
Attitude of Health Personnel, Humans, Medical Oncology, Perception, Neoplasms, Nurses
Abstract

Background: Death is one of the basic theme with which nurses are faced, and for which it is hard for them to prepare deeply and sincerely. The difficulties in handling the emotional burden can cause them to develop negative feelings towards life and clinical practice, so that it affects their caregiving capacity and the quality of care provided., Aim: To explore nurses' perceptions facing the death of a hospitalized oncology patient., Methods: Qualitative phenomenological study. The sample of nurses was recruited at IRCCS (Scientific Institute for Research and Healthcare) in Rome, a hospice in Latina and a hospice in Rieti. The data were collected by means of focus groups. The semi-structured interviews featuring three guiding questions constructed for this purpose, were audio-recorded, transcribed, and then analyzed using the analysis framework approach., Results: In total 7 focus groups were conducted with a total participation of 39 nurses. Four themes emerged from the qualitative analysis: "The different meanings of death", "The rupture of death", "The perceptual variables of death", and "Requests for help"., Conclusion: The study highlighted the need to provide nurses with substantial psychological and emotional support, and give consideration to organizational and environmental factors for better management of the event of death in oncology.

Published
2021
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26. The Effectiveness of the Sport "Dragon Boat Racing" in Reducing the Risk of Lymphedema Incidence: An Observational Study.

Author

Iacorossi L, Gambalunga F, Molinaro S, De Domenico R, Giannarelli D, and Fabi A

Subjects
Adaptation, Psychological, Body Mass Index, Female, Humans, Middle Aged, Ships, Surveys and Questionnaires, Breast Neoplasms prevention & control, Exercise psychology, Lymphedema prevention & control, Quality of Life psychology, Self Concept, Sports psychology
Abstract

Background: Upper extremity lymphedema is a complication that often occurs in women with breast cancer as a result of surgery and/or radiotherapy. Some studies report that a boating activity known as the "dragon boat" sport can benefit these women., Aim: The aim of this study was to assess whether this type of sport prevents or reduces lymphedema, its impact on quality of life (QoL), and the possible predictors of this condition., Methods: This was an observational study of 2 groups: group A (women who participated in dragon boat racing for at least 6 months) and group B (women who participated in other forms of physical exercise biweekly). Data were collected at the National Cancer Institute of Rome and the lake of Castel Gandolfo from June to October 2016. The instruments used were a questionnaire created for sociodemographic and clinical data, the European Organisation for Research and Treatment of Cancer Core Questionnaire for evaluating QoL, and a tape measure applied to estimate the local lymphedema., Results: One hundred women participated in the study. Lymphedema incidence in group A was 4.0% (2 of 50), whereas in group B it was 26.0% (13 of 50). Women who participated in dragon boat racing also reported a healthier lifestyle, lower body mass index, and a better QoL (set point: 61.8 group B vs 80.0 group A)., Conclusions: The dragon boat sport participants had more positive clinical and QoL outcomes than did the women who did not participate in that sporting activity., Implications for Clinical Practice: It would be important to make women with breast cancer aware of the practice of dragon boat racing.

Published
2019
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27. Qualitative study of patients with metastatic prostate cancer to adherence of hormone therapy.

Author

Iacorossi L, Gambalunga F, De Domenico R, Serra V, Marzo C, and Carlini P

Subjects
Aged, Aged, 80 and over, Benzamides, Humans, Male, Nitriles, Phenylthiohydantoin therapeutic use, Prostatic Neoplasms, Castration-Resistant pathology, Qualitative Research, Treatment Outcome, Abiraterone Acetate therapeutic use, Antineoplastic Agents therapeutic use, Medication Adherence, Phenylthiohydantoin analogs & derivatives, Prostatic Neoplasms, Castration-Resistant drug therapy, Prostatic Neoplasms, Castration-Resistant psychology
Abstract

Purpose: To explore adherence to oral hormone treatment in patients with metastatic prostate cancer (mCRPC) and to identify the factors that influence it., Methods: A qualitative exploratory study was conducted at the National Cancer Institute of Rome. Patients aged >18 years with castration-resistant prostate cancer (mCRPC) and who were using oral hormone drugs were recruited. Semi-structured interviews were used for data collection, subsequently transcribed verbatim and analysed using Ritchie and Spencer's framework analysis., Results: The sample included 13 patients with a median age of 72 who were treated, on average, for seven months with abiraterone acetate (AA) (76.9%) and enzalutamide (ENZ) (23.1%). Five themes were identified: expression of the concept of adherence, favouring factors, obstacle factors, functional strategies and levels of adherence., Conclusions: The patients express a good level of adherence, which they define in different ways-the helping relationship with the attending physician, the support of the family members and the few side effects of the drugs. For the future, it is recommended to perform a multicentre mixed method study to explain the levels of adherence and distress in women with breast cancer., (Copyright © 2018 Elsevier Ltd. All rights reserved.)

Published
2019
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28. [Right atrial appendage thrombosis during atrial fibrillation: an element to look for].

Author

Barbati G, De Domenico R, Rossi S, Vecchiato E, and Zeppellini R

Subjects
Humans, Male, Middle Aged, Atrial Appendage surgery, Atrial Fibrillation complications, Thrombosis etiology
Abstract

Oral anticoagulant therapy (OAT) is a mainstay of atrial fibrillation (AF) pharmacological treatment. Left atrial appendage closure is a possible treatment, when feasible, in patients with intracerebral hemorrhage during OAT. We report a case of right atrial appendage thrombosis in a patient with chronic AF admitted for syncope due to diuretic-induced orthostatic hypotension. Two years previously, he had undergone left atrial appendage closure with the Amplatzer Cardiac Plug device because of intracerebral hemorrhage during OAT. After neurological consult, OAT was resumed with apixaban 5 mg twice daily, and transesophageal echocardiography performed two months later showed complete resolution of the right atrial appendage thrombosis. This particular case underlines the importance of searching for a possible right atrial appendage thrombosis in patients affected by AF, and suggests that left atrial appendage closure in AF patients not suitable for OAT does not fully eliminate the risk of thromboembolism.

Published
2017
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29. Visceral obesity predicts adverse pathological features in urothelial bladder cancer patients undergoing radical cystectomy: a retrospective cohort study.

Author

Cantiello F, Cicione A, Autorino R, Salonia A, Briganti A, Ferro M, De Domenico R, Perdonà S, and Damiano R

Subjects
Aged, Carcinoma, Transitional Cell surgery, Cohort Studies, Cystectomy, Female, Humans, Logistic Models, Lymph Node Excision, Male, Middle Aged, Multivariate Analysis, Neoplasm Invasiveness, Neoplasm Staging, Pelvis, Prognosis, Retrospective Studies, Risk Factors, Urinary Bladder Neoplasms surgery, Carcinoma, Transitional Cell pathology, Lymph Nodes pathology, Metabolic Syndrome, Muscle, Smooth pathology, Obesity, Abdominal, Urinary Bladder pathology, Urinary Bladder Neoplasms pathology
Abstract

Purpose: To evaluate the pathological characteristics of patients with metabolic syndrome (MetS) undergoing radical cystectomy (RC) for urothelial bladder cancer (BCa)., Methods: We retrospectively analyzed 262 consecutive patients with muscle-invasive urothelial BCa or non-muscle-invasive urothelial BCa bacillus Calmette-Guerin refractory undergoing RC with standard pelvic lymphadenectomy. The patients were stratified into those with or without MetS, and a bivariate logistic regression analysis was done to assess MetS and, separately, each single MetS component as independent predictors of higher pathological stage as well as of the presence of lymph vascular invasion (LVI) and lymph node metastasis (LM)., Results: Metabolic syndrome was found in 36.3 % of patients. At logistic regression analysis, the presence of MetS did not predict the risk of both higher pathological stage and LVI and LM. Investigating the single components of MetS after adjusting for age, gender, and smoking, the risk of higher pathological stage increased with body mass index [BMI (OR 1.307, 95 % CI 1.098-1.555)], waist circumference (OR 1.414, 95 % CI 1.364-1.668), and blood hypertension (OR 2.326, 95 % CI 1.147-4.717). Higher BMI also predicted the presence of LVI (OR 1.432, 95 % CI 1.173-1.748) and LM (OR 1.202, 95 % CI 0.951-1.519), whereas HDL cholesterol was inversely associated with the risk of LVI and LM., Conclusions: Metabolic syndrome does not represent an independent risk factor for worse pathological findings in BCa. Conversely, individual components of MetS could increase the risk of higher stage as well as LM.

Published
2014
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30. EGFR mutational status in penile cancer.

Author

Di Lorenzo G, Buonerba C, Gaudioso G, Gigantino V, Quarto G, De Domenico R, Caraglia M, Di Trolio R, Ascierto PA, De Placido S, Perdonà S, and Franco R

Subjects
ErbB Receptors metabolism, Humans, Male, Mutation, Penile Neoplasms metabolism, Tissue Array Analysis, ErbB Receptors genetics, Penile Neoplasms genetics
Abstract

Objective: No substantial improvement in overall survival has been obtained over the past two decades in penile cancer (PC). Clinical data are available on the role of epidermal growth factor receptors (EGFR) inhibitors in PC but no EGFR mutational analysis has been conducted., Research Design and Methods: We reviewed formalin-fixed, paraffin-embedded blocks of PC at the Pathology Department of the National Cancer Institute since 2000 through 2012 to evaluate activating mutations in the tyrosine kinase domain of EGFR: EGFR E746 - A750 specific deletion in exon 19 and EGFR L858R specific point mutation in exon 21., Results: Thirty tumor samples were available for our analysis. EGFR was expressed in all samples at immunohistochemistry. Tested mutations were not identified in any of the samples analyzed., Conclusions: The most frequent activating EGFR mutations detected in non-small setting lung cancer are absent in penile cancer (PC). Sequencing of the entire EGFR gene in patients with PC may provide useful insights, as its mechanism of overexpression and activation in PC remains unknown.

Published
2013
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31. Treatment of gestational diabetes: oral hypoglycemic agents or insulin?

Author

Faraci M, Di Prima FA, Valenti O, Hyseni E, Monte S, Giorgio E, and De Domenico R

Abstract

Our report aims to verify whether perinatal maternal glycemic control in gestational diabetes can only be achieved with insulin or with oral hypoglycaemic agents. Then we want to evaluate the efficacy and safety of oral hypoglycemic agents in the treatment of gestational diabetes and then to compare these results with those associated with the use of insulin.

Published
2011

33. Fetal cardiac function during the first trimester of pregnancy.

Author

Valenti O, Di Prima FA, Renda E, Faraci M, Hyseni E, De Domenico R, Monte S, and Giorgio E

Abstract

Chromosomally normal first trimester fetuses with an increased nuchal translucency measurement have an elevated risk of congenital heart defect (CHD). so there is an increased demand for imaging the fetal heart during the first and early second trimesters of pregnancy.Echocardiographic and anatomical correlations in firsttrimester fetuses show that by 11 weeks' gestation, the position of the fetal heart within the chest is similar to that in later gestation, and the spatial relation of the great arteries and their relative sizes are similar to those on second-trimester scans by 12 weeks' gestation.In the first trimester during the heart analysis it's possible value: anatomic structure (size, rate), hemodynamic development through analysis of these waveforms and flow patterns (inflow and outflow waveforms of the diastolic filling and the systolic ejection) and modification during the first trimester.

Published
2011

34. Maternal weight gain during pregnancy and neonatal birth weight: a review of the literature.

Author

Monte S, Valenti O, Giorgio E, Renda E, Hyseni E, Faraci M, De Domenico R, and Di Prima FA

Abstract

Obesity has become a serious global public health issue and has consequences for nearly all areas of medicine. Within obstetrics, obesity not only has direct implications for the health of a pregnancy but also impacts on the weight of the child in infancy and beyond. As such, maternal weight may influence the prevalence and severity of obesity in future generations. Pregnancy has been identified as a key time to target a weight control or weight loss strategy to help curb the rapidly growing obesity epidemic. This study reviews the current evidence for interventions to promote weight control or weight loss in women around the time of pregnancy. Studies have shown positive correlations between both maternal pre-pregnancy weight and gestational weight gain with the birth weight of the infant and associated health risks, so interventions have been put to clinical trials at both time points. Many women are concerned about the health of their babies during pregnancy and are in frequent contact with their healthcare providers, pregnancy may be an especially powerful "teachable moment" for the promotion of healthy eating and physical activity behaviors among women.

Published
2011

35. Antiphospholipid Syndrome during pregnancy: the state of the art.

Author

Di Prima FA, Valenti O, Hyseni E, Giorgio E, Faraci M, Renda E, De Domenico R, and Monte S

Abstract

Obstetric complications are the hallmark of antiphospholipid syndrome. Recurrent miscarriage, early delivery, oligohydramnios, prematurity, intrauterine growth restriction, fetal distress, fetal or neonatal thrombosis, pre-eclampsia/eclampsia, HELLP syndrome, arterial or venous thrombosis and placental insufficiency are the most severe APS-related complication for pregnant women. Antiphospholipid antibodies promote activation of endothelial cells, monocytes and platelets, causing an overproduction of tissue factor and thromboxane A2. Complement activation might have a central pathogenetic role. These factors, associated with the typical changes in the hemostatic system during normal pregnancy, result in a hypercoagulable state. This is responsible of thrombosis that is presumed to provoke many of the pregnancy complications associated with APS. Obstetric care is based on combined medical-obstetric high-risk management and treatment with the association between aspirin and heparin. This review aims to deter- mine the current state of the art of APS by investigating the knowledge achievements of recent years, to provide the most appropriate diagnostic and therapeutic management for pregnant women suffering from this syndrome.

Published
2011

36. Increased nuchal traslucency in normal karyotype fetuses.

Author

De Domenico R, Faraci M, Hyseni E, Di Prima FA, Valenti O, Monte S, Giorgio E, and Renda E

Abstract

Nuchal traslucency (NT) measurement between 11 and 14 weeks' gestation is a reliable marker for chromosomal abnormalities, including trisomy 21. However, even if conventional karyotyping is normal, increased NT is a predictive value of adverse pregnancy outcome, because it is associated with several fetal malformations, congenital heart defects, genetic syndromes, intrauterine death and miscarriages; the majority of these structural anomalies are undetectable before birth. The risk is proportional to the nuchal translucency thickness, in fact it statistically increases after measurement reaching 3.5 mm or more. However, when these chromosomally normal fetuses with an enlarged NT survive, even if a detailed ultrasound examination and echocardiography fail to reveal any abnormalities, their uneventful outcome and postnatal developmental delay will be not statistically increased when compared to the general population. These parents should be confidently reassured that the residual chance of structural anomalies and abnormal neurodevelopment may not be higher than in the general population.

Published
2011

37. Fetal growth restriction: current perspectives.

Author

Faraci M, Renda E, Monte S, Di Prima FA, Valenti O, De Domenico R, Giorgio E, and Hyseni E

Abstract

Intrauterine growth restriction is one of the most common and complex problems in modern obstetrics. The cut off value mainly used for defining an IUGR is at the 10th percentile. There are many evidence demonstrating that the adverse perinatal outcome are mainly confined to infants below the 5th or 3th percentile. The mains causes for the onset of IUGR can be divided into three categories: maternal, fetal and placental. Aim of this study is to obtain a review from which speculate useful indication in clinical practice. Evidence from randomized controlled trials finds few interventions beneficial in preventing or treating IUGR.

Published
2011

38. First- and second-trimester ADAM12s in Down syndrome screening.

Author

Baviera G, Chimicata S, De Domenico R, Granese R, Carbone C, Dugo N, and D'Anna R

Subjects
ADAM12 Protein, Adult, Down Syndrome prevention & control, Female, Humans, Mass Screening, Pregnancy, Pregnancy Trimester, First, Pregnancy Trimester, Second, ADAM Proteins blood, Down Syndrome blood, Membrane Proteins blood
Published
2010
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39. What happens to the abstracts presented at the Societè Internationale d'Urologie meeting?

Author

Autorino R, Quarto G, Di Lorenzo G, Giugliano F, Quattrone C, Neri F, De Domenico R, Sorrentino D, Mordente S, Damiano R, and De Sio M

Subjects
Abstracting and Indexing statistics & numerical data, Congresses as Topic, Publishing statistics & numerical data, Urology
Abstract

Objectives: To estimate the acceptance rate on peer-reviewed journals, describe the time-course of subsequent full publication, and identify those with characteristics associated with publication from the abstracts presented at the Societè Internationale d'Urologie (SIU) meeting., Methods: All abstracts accepted for presentation at the annual 2002 and 2004 SIU meetings were identified from the published supplements in the BJU International. The subsequent publication rate for the corresponding studies by scanning Medline was evaluated., Results: Overall, 1877 abstracts were presented, 415 of which (22.1%) were followed by publication in peer-reviewed journals. The mean time to publication was 13 months (range, 1 to 45 months). A total of 60.6% of the published articles were in print within 1 year of presentation "In most of the cases the reports were published in The Journal of Urology (76 reports) and in Urology (49 reports). Abstracts on kidney cancer, urinary diversion, incontinence, and urolithiasis had the highest publication rates (43.4%, 36.6%, 33.3%, and 29.2%, respectively). Studies from North America and from Oceania had the highest publication rate (26.8% and 26.6%, respectively)., Conclusions: One fifth of the abstracts presented at the SIU meetings are ultimately published in indexed journals. Delegates attending these meetings should be aware of this issue when taking into account findings from meeting reports for their clinical practice. Factors influencing their publication are the abstract geographical area of origin, the study subject, and the research type. The Journal of Urology and Urology represented target journals for the publication more than other ones.

Published
2008
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40. A new transportable shock-wave lithotripsy machine for managing urinary stones: a single-centre experience with a dual-focus lithotripter.

Author

De Sio M, Autorino R, Quarto G, Mordente S, Giugliano F, Di Giacomo F, Neri F, Quattrone C, Sorrentino D, De Domenico R, and D'Armiento M

Subjects
Equipment Design, Female, Humans, Lithotripsy adverse effects, Lithotripsy standards, Male, Middle Aged, Prospective Studies, Risk Factors, Treatment Outcome, Kidney Calculi therapy, Lithotripsy instrumentation, Ureteral Calculi therapy
Abstract

Objective: To assess the efficacy and safety of a transportable extracorporeal shock wave lithotripsy (ESWL) machine, the Modulith SLX-F2(TM) (Storz Medical Italia, Rome, Italy), in the management of solitary urinary calculi., Patients and Methods: The study included 233 patients (mean age 51 years; 172 male, 61 female) with symptomatic solitary renal (group A, 170, mean diameter 15.5 mm) or ureteric stones (group B, 63, mean diameter 9.5 mm) treated in a tertiary care institution. Exclusion criteria for the analysis were: pelvi-ureteric junction obstruction, multiple stones, stone diameter >2 cm, stones in a lower calyx with unfavourable anatomy, active infection, or impacted ureteric stones. Selected patients had ureteric stenting before treatment, and all patients were treated with no anaesthesia. Hospitalization, complications and subsequent auxiliary procedures were evaluated. Patients were assessed after a single ESWL session and after 3 months by a plain abdominal film and renal ultrasonography. Stone-free status was defined as no evidence of calculi, and clinical success as the presence of stone fragments of <4 mm. An efficiency quotient (EQ) was calculated for the ESWL treatment. Pain was assessed using a visual analogue scale., Results: The mean number of shocks used was 3779 and the mean (range) treatment time was 35 (5-55) min. The overall clinical success rate after one ESWL session was 83.7% and 82.5% for renal and ureteric stones, respectively, and the overall 3-month stone-free rate was 77% and 74.6%, respectively; the overall EQ was 0.64. When risk factors for persistent calculi were analysed simultaneously in a logistic regression model, only stones of >1 cm were statistically significant (P < 0.05). Most patients reported that pain during ESWL was mild to moderate and easily tolerated. Only minor complications occurred, with an overall complication rate of 3.8%., Conclusions: This transportable lithotripter is a safe and effective device for managing solitary stones throughout the urinary tract. Its main advantage is represented by the dual-focus system. Moreover, it shares with other contemporary machines several important features such as outpatient setting, no need for anaesthesia, easy patient positioning, and the capability of ancillary procedures.

Published
2007
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41. [Relation between left atrial spontaneous echocontrast and pulmonary venous flow in nonvalvular atrial fibrillation: implications for stratification of thromboembolic risk].

Author

Vendrametto F, Zeppellini R, De Domenico R, Rigo T, Zadro M, Bolognesi R, Barilli L, and Cucchini F

Subjects
Aged, Atrial Fibrillation complications, Female, Humans, Male, Risk Factors, Thromboembolism epidemiology, Thromboembolism etiology, Ultrasonography, Atrial Fibrillation diagnostic imaging, Atrial Fibrillation physiopathology, Heart Atria diagnostic imaging, Pulmonary Circulation
Abstract

Background: The links between pulmonary venous flow (PVF) and left atrial stasis have not been adequately defined in nonvalvular atrial fibrillation. In this setting, we aimed to study the relationship between PVF and the occurrence of left atrial spontaneous echocontrast (SEC) in order to evaluate its clinical relevance in the assessment of the cardioembolic risk., Methods: We studied by echocardiography 109 patients with nonvalvular atrial fibrillation (65 males, 44 females, mean age 66 +/- 9 years). The left ventricular end-diastolic and end-systolic diameters, the left ventricular fractional shortening, the left ventricular mass, and the left atrial volume were measured by transthoracic approach. The systolic and diastolic peak velocities of PVF, their ratio (pS/pD) and the velocity-time integrals were assessed by means of transesophageal investigation; furthermore, the presence of left atrial SEC or thrombi was recorded. Among clinical data, thromboembolic events occurring within 15 days before the echocardiographic study, history of hypertension and duration of atrial fibrillation were also collected., Results: Left atrial SEC showed a significant correlation with left atrial volume (p < 0.001), detection of thrombi (p < 0.001), thromboembolic events (p = 0.002) and pS/pD ratio (p < 0.001). By multivariate analysis, pS/pD ratio was independently correlated with left atrial volume, age and left ventricular fractional shortening (r2 = 0.29, p < 0.001). The sensitivity and specificity of pS/pD ratio to predict the presence of severe SEC was 73.9 and 62.5%, respectively., Conclusions: In patients with nonvalvular atrial fibrillation, pS/pD ratio is significantly related to the occurrence of left atrial SEC and seems to be a useful parameter concurring to assess left atrial stasis and thromboembolic risk.

Published
2002

42. Aortic intramural hematoma: an increasingly recognized aortic disease.

Author

Bolognesi R, Manca C, Tsialtas D, Vasini P, Zeppellini R, De Domenico R, Cucchini F, and Visioli O

Subjects
Aged, Aged, 80 and over, Aortic Dissection complications, Aortic Dissection diagnosis, Aortic Aneurysm, Thoracic complications, Aortic Aneurysm, Thoracic diagnosis, Aortic Diseases complications, Aortography, Diagnosis, Differential, Echocardiography, Transesophageal, Electrocardiography, Fatal Outcome, Follow-Up Studies, Hematoma complications, Humans, Male, Middle Aged, Retrospective Studies, Tomography, X-Ray Computed, Aortic Diseases diagnosis, Hematoma diagnosis
Abstract

Aortic intramural hematoma (IMH) is a rarely diagnosed pathological condition that is not well characterized to date. We diagnosed IMH in 4 of 31 patients with suspected aortic dissection admitted to our coronary care unit from 1992 to 1995. In all 4 cases, IMH was located in the ascending aorta. At the time of hospitalization, all patients showed tachycardia, hypotension and pericardial effusion. Diagnosis of IMH was made by transesophageal echocardiography and computed tomography. We performed aortography in 2 patients, but it was non-diagnostic in both of them. One patient died before surgery. Autopsy confirmed the diagnosis of IMH and showed severe pericardial effusion. In another patient, the diagnosis was confirmed during successful surgery, while the remaining 2 patients recovered after medical therapy. The 3 surviving patients are still under follow-up control 12, 16 and 20 months after the initial acute event. We briefly discuss the epidemiological, clinical, diagnostic, therapeutic and prognostic aspects of IMH.

Published
1998
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43. Threshold energy dose for enzyme release after direct-current countershock.

Author

Gheno G, Zeppellini R, De Domenico R, and Cucchini F

Subjects
Adult, Aged, Aged, 80 and over, Biomarkers, Creatine Kinase blood, Electric Countershock adverse effects, Female, Humans, Isoenzymes, Male, Middle Aged, Reference Values, Time Factors, Creatine Kinase metabolism, Tachycardia therapy
Abstract

Serial measurement of serum total creatine kinase and creatine kinase MB isoenzyme was prospectively performed by photometric assay in 82 consecutive patients (55 male and 27 female; mean age 62 +/- 11 years) after elective DC countershock for atrial flutter or fibrillation. Enzyme release is commonly observed to follow DC shock; the related energy threshold for enzyme release, however, a parameter with potential clinical usefulness, has not yet been determined. The energy dose was individually titrated but the anterolateral paddle-electrode location was used in all cases. The mean +/- S.D. (range) of shock number, peak energy level and cumulative energy dose normalized to body weight were respectively: 1.7 +/- 0.9 (1-5), 228.6 +/- 87.6 (75-400) J and 5.26 +/- 3.74 (1.0-19.7) J/kg. All these parameters had highly significant positive correlation with enzyme release (P < 0.0001), which peaked 16 h after countershock. Only creatine kinase levels changed significantly vs. baseline (P < 0.0001). As evidenced by dose vs. effect scattergram, the energy threshold value for enzyme release was around 4 J/kg for creatine kinase and 6 J/kg for creatine kinase MB isoenzyme. These energy dose figures may provide clinical usefulness to avoid unnecessary muscle damage; moreover, they may be used as a reference when enzyme elevations interfere with the diagnosis of a concomitant ischemic acute myocardial infarction.

Published
1996
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44. Do inotropic drugs always induce a positive lusitropic effect? A comparison between k-strophanthidin and dobutamine in patients with coronary artery disease.

Author

Cucchini F, Bolognesi R, Javernaro A, Zeppellini R, De Domenico R, and Visioli O

Subjects
Age Factors, Aged, Diastole drug effects, Female, Hemodynamics drug effects, Humans, Male, Matched-Pair Analysis, Middle Aged, Sex Factors, Systole drug effects, Coronary Disease physiopathology, Dobutamine pharmacology, Myocardial Contraction drug effects, Strophanthidin pharmacology, Ventricular Function, Left drug effects
Abstract

The interaction between systolic and diastolic effects of inotropic drugs is an important subject which has not yet been fully clarified in the cardiological literature. The effects of the inotropic drugs k-strophanthidin and dobutamine on left ventricular (LV) relaxation and early filling phase were compared in patients with coronary artery disease (CAD) and preserved systolic function. Twenty-two patients were randomly divided into two groups; group I was infused with 0.0035 mg.kg-1 of k-strophanthidin for 10 min and group II with dobutamine at a rate of 10 micrograms.kg-1.min-1 for 10 min. Both groups underwent simultaneous haemodynamic and echo 2D-Doppler evaluations at controlled heart rate. K-strophanthidin improved contractility indexes (peak of LV systolic pressure P < 0.001, max dP/dt + P < 0.05 and dP/dt P < 0.01) and worsened T constant and LV lowest diastolic pressure, (LVLDP) (P < 0.001 and P < 0.05 respectively) without changing early transmitral filling parameters. Dobutamine induced a significant increase in contractility in group II but at the same time significantly improved LV relaxation variables (max dP/dt - P < 0.01 and T constant P < 0.001). In addition, dobutamine reduced LVLDP (P < 0.05) and significantly increased LV early filling parameters. These results show that an acute administration of either k-strophanthidin or dobutamine enhances contractility, whereas these drugs have the opposite effect on the early diastolic phase.

Published
1994
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46. Double orifice in prolapsing mitral valve.

Author

De Domenico R, Gheno G, and Cucchini F

Subjects
Adult, Echocardiography, Doppler, Follow-Up Studies, Humans, Male, Mitral Valve diagnostic imaging, Mitral Valve Insufficiency congenital, Mitral Valve Insufficiency diagnostic imaging, Mitral Valve Prolapse diagnostic imaging, Echocardiography, Mitral Valve abnormalities, Mitral Valve Prolapse congenital
Abstract

A prolapsing mitral valve with a double orifice ('hole type') was documented by echocardiography in a 35-year-old male. His symptoms were associated to supraventricular ectopic beats and persisted unchanged during a 3-year follow-up. This malformation is usually considered benign but, as fragmentation of the atrioventricular conduction tissue was reported in some cases, a periodic observation is advisable.

Published
1993
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48. [Chronic treatment of dilated cardiomyopathy by beta blocking agents. Clinical and hemodynamic follow-up].

Author

Cucchini F, Compostella L, Papalia D, de Domenico R, Iavernaro A, and Zeppellini R

Subjects
Cardiac Catheterization, Cardiomyopathy, Dilated physiopathology, Clinical Trials as Topic, Echocardiography, Electrocardiography, Female, Follow-Up Studies, Hemodynamics, Humans, Male, Metoprolol therapeutic use, Middle Aged, Prospective Studies, Random Allocation, Time Factors, Adrenergic beta-Antagonists therapeutic use, Cardiomyopathy, Dilated drug therapy
Abstract

symptomatic dilated cardiomyopathy were studied in order to evaluate the effect of long term sympathetic beta-blockade with metoprolol. Clinical evaluation, stress test, two-dimensional echocardiography, 24 hour ambulatory electrocardiography and hemodynamic assessment with Swan-Ganz catheter were performed before enrollment in the study. Patients were randomly assigned to the relative placebo (8 pts) or metoprolol group (12 pts) in a single-blind fashion. The placebo group received standard therapy (digitalis, diuretics, vasodilators and anticoagulants as needed), while the metoprolol group, along with standard therapy received low-dose beta-blockade, starting with 6.25 mg twice daily and then doubling every 4 days on the two daily administrations. The therapeutic end-point was 100 mg. Patients received less than 100 mg if their systolic blood pressure was less than 100 mmHg or if their resting heart rate was less than 55 beats/min. Patients were clinically assessed every month and a 24-hour electrocardiography, echocardiography and hemodynamic control was repeated after six months. In the metoprolol group there was one sudden death and two drop-outs.(ABSTRACT TRUNCATED AT 250 WORDS)

Published
1988

49. [Early changes in ventricular function in diastolic phase in the resting coronary patient].

Author

Cucchini F, Barilli A, Bolognesi R, Compostella L, De Domenico R, Javernaro A, Papalia D, Zeppellini R, and Cardaioli P

Subjects
Cardiac Catheterization, Computers, Humans, Rest, Systole, Coronary Disease physiopathology, Diastole, Myocardial Contraction
Abstract

The aim of this study is to test left ventricular diastolic function in coronary artery disease patients with preserved systolic performance. Two groups of patients (25 coronary artery disease patients with angiographic proved coronary artery stenosis, but with normal hemodynamic and angiographic indices of systolic phase, first group; and 14 normal subjects for control, second group) were tested comparing their systolic and diastolic ventricular function indices, obtained by using a Millar microtip catheter and a computerized program. Systolic ventricular function was similar in the two groups (EF: 0.61 +/- 0.05 vs 0.62 +/- 0.03, p: n.s.; Vmax:120 +/- 28 vs 112 +/- 24 sec-1, p: n.s.), while diastolic indices were significantly different (lowest diastolic pressure: 3.7 +/- 2.4 vs -1.72 +/- 1.45 mmHg, p less than 0.01; end-diastolic pressure: 11.2 +/- 4.2 vs 6.5 +/- 2.8 mmHg, p less than 0.05; T constant: 45 +/- 8 vs 35 +/- 6 mmHg, p less than 0.001; end-diastolic compliance: 2.79 +/- 0.3 X 10(-2) vs 5.68 +/- 0.4 X 10(-2) mmHg-1, p less than 0.001; Kp: 0.041 +/- 0.006 vs 0.003 +/- 0.004 p less than 0.001). In conclusion, impairment of left ventricular diastolic phase may be one of the earliest manifestations of functional alterations of ischemic ventricle.

Published
1986

50. [Effect of propafenone on the pharmacokinetics of digoxin administered orally: a study in healthy volunteers].

Author

Cardaioli P, Compostella L, De Domenico R, Papalia D, Zeppellini R, Libardoni M, Pulido E, and Cucchini F

Subjects
Administration, Oral, Adult, Digoxin administration & dosage, Drug Interactions, Humans, Kinetics, Male, Propafenone, Anti-Arrhythmia Agents pharmacology, Digoxin metabolism, Propiophenones pharmacology
Abstract

It is well known that many cardiovascular drugs affect digoxin kinetics, but nothing is defined on propafenone-digoxin interaction. To clarify this problem, we studied digoxin kinetics in 8 healthy men, who received digoxin oral dose (0.50 mg) in the control state and again during maintenance therapy with propafenone (150 mg q.i.d.). Statistically significant changes were observed during propafenone in a number of digoxin kinetic indexes: a rise in peak serum digoxin concentration (4.30 vs 3.07 ng/ml - p less than 0.005), in area under the serum-digoxin concentration curve (4 h: 520.4 vs 368.9; 10 h: 789.6 vs 621.3 ng X min/ml - p less than 0.005; 24 h: 1187.6 vs 954.7 ng X min/ml - p less than 0.05) and urinary excretion of digoxin (277.7 vs 203.5 mcg - p less than 0.005). Renal digoxin clearance was not affected by propafenone. We conclude that propafenone interact kinetically with digoxin in healthy subjects, perhaps increasing digoxin bioavailability.

Published
1986

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