1. Traditional Mexican dietary pattern and cancer risk among women of Mexican descent.
- Author
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Loroña, Nicole, Santiago-Torres, Margarita, Lopez-Pentecost, Melissa, Sun, Yangbo, Kroenke, Candyce, Snetselaar, Linda, Stefanick, Marcia, Neuhouser, Marian, Garcia, Lorena, and Shadyab, Aladdin
- Subjects
Breast cancer ,Cancer risk ,Colorectal cancer ,Dietary pattern ,Mexican diet ,WHI ,Humans ,Female ,Middle Aged ,Diet ,Mexican Americans ,Risk Factors ,Colorectal Neoplasms ,Aged ,Mexico ,Breast Neoplasms ,Incidence ,Neoplasms ,Dietary Patterns - Abstract
PURPOSE: To examine the association of a traditional Mexican diet score with risk of total, breast, and colorectal cancer among women of Mexican ethnic descent in the Womens Health Initiative (WHI). METHODS: Participants were WHI enrollees who self-identified as being of Mexican descent. Data from food frequency questionnaires self-administered at study baseline were used to calculate the MexD score, with higher scores indicating greater adherence to an a priori-defined traditional Mexican diet (high in dietary fiber, vegetables, and legumes). Incident cancers were self-reported by participants from 1993 to 2020 and adjudicated by trained physicians. We used multivariable-adjusted Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: Among 2,343 Mexican descent women (median baseline age: 59 years), a total of 270 cancers (88 breast, 37 colorectal) occurred during a mean follow-up of 14.4 years. The highest tertile of MexD score was associated with a lower risk of all-cancer incidence (HR: 0.67; 95% CI 0.49-0.91; p-trend: 0.01) and colorectal cancer (HR: 0.38; 95% CI 0.14-0.998; p-trend
- Published
- 2024