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COVID-19 pandemic has a significant impact on public health, whether directly or indirectly. The first case was seen in Turkey on March 11, and the World Health Organization (WHO) declared a pandemic on March 12, 2020. The study aimed to document the effect of pandemic on dermatology outpatient clinics in Turkey. 15 tertiary hospitals from 13 provinces were included in the study, which was conducted between January 12 and May 12, 2020. The International Codes of Diseases (ICD-10) categories and patients' characteristics were evaluated before and after the pandemic. A total of 164878 patients, 133131 before and 31747 after the pandemic, were evaluated. The daily hospital applications were found reduced by 77%. The three of the most frequent diagnoses; dermatitis, acne, and psoriasis remained unchanged after the pandemic. While the frequency of herpes zoster, scabies, urticaria, pityriasis rosea and sexually transmitted diseases increased significantly; allergic and irritant contact dermatitis decreased after the pandemic. The applications regarding cutaneous neoplasms were considerably reduced during the pandemic, and this effect was more pronounced in cities with higher COVID incidence. The pandemic caused a noteworthy reduction in the number of patients accessing dermatological care. The pandemic caused significant changes in the frequency of a wide range of dermatological diseases. The application of cutaneous neoplasms is considerably reduced after the pandemic, and this effect was more pronounced in cities where pandemics are frequent. Therefore, the pandemic has resulted on numerous impacts on many critical issues in dermatology and dermatological care. This article is protected by copyright. All rights reserved.

WOS: 000313861400013 ‘‘Liken miksödematozus’’ deride fibroblast artışı ve müsin birikimi ile karakterize primer inflamatuvar bir dermatozdur. Skleromiksödem liken miksödematozusun jeneralize formu olup papüler lezyonlar, difüz skleroz ve eritem ile seyreder. Sıklıkla paraproteinemilerle birliktelik gösterir. Monoklonal gamopatisiz skleromiksödem ise liken miksödematozusun daha nadir görülen atipik bir varyantıdır. Sistemik tutulum da gösterebilen ve bazen fatal olabilen hastalığın tedavisinde olgu bildirileri şeklinde çok çeşitli seçenekler denense de henüz kesin bir tedavi şekli yoktur. İntravenöz immünglobulin ile yapılan olgu bildirilerinde ise yüz güldürücü sonuçlar elde edilmiştir. Skleromiksödemin etyopatogenezi tam olarak anlaşılamadığı gibi intravenöz immünglobulinin de skleromiksödemdeki etki mekanizması hâlen net değildir. Burada monoklonal gamopatinin eşlik etmediği bir skleromiksödem olgusu ve intravenöz immünglobulin tedavisine yanıtı sunulmaktadır. (Türk derm 2012; 46: 223-5) Lichen myxedematosus is a primary inflammatory dermatosis characterized by fibroblast proliferation and mucin deposition in the skin. Scleromyxedema is the generalized variant of lichen myxedematosus and is accompanied by papular lesions, diffuse sclerosis and erythema. It is usually associated with paraproteinemias. Scleromyxedema without monoclonal gammopathy is a rare and atypical variant of lichen myxedematosus. Systemic involvement and sometimes fatal course can be seen with scleromyxedema. Although several treatment modalities have been tried, there is no definitive treatment available for the disease. Satisfactory results have been obtained in the case reports in which intravenous immunoglobulin treatment was used.The mechanism of action of intravenous immunoglobulin in scleromyxedema is still not clear as well as the etiopathogenesis of scleromyxedema. Herein, we describe the case of a patient with scleromyxedema without monoclonal gammopathy and his response to the treatment with intravenous immunoglobulin. (Turkderm 2012; 46: 223-5)