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22 results on '"Dainty, Louis A."'

7. A practical approach to using low-molecular-weight heparin in gynecologic surgery patients. (Lmwh in Gynecologic Surgery)

Author

Dainty, Louis A., Maxwell, G. Larry, and Clarke-Pearson, Daniel L.

Subjects
Pulmonary embolism -- Risk factors -- Complications and side effects, Gynecology, Operative -- Safety and security measures -- Usage, Venous thrombosis -- Risk factors -- Complications and side effects
Abstract

Deep venous thrombosis (DVT) and pulmonary embolism (PE) are major complications of surgery for gynecologic cancer that result in significant morbidity and mortality. Approximately 260,000 cases of clinically diagnosed DVT [...]

Published
2003

8. Management of recurrent granulosa cell tumor of the ovary: Contemporary literature review and a proposal of hyperthermic intraperitoneal chemotherapy as novel therapeutic option.

Author

Yasukawa, Maya, Matsuo, Koji, Matsuzaki, Shinya, Dainty, Louis A., and Sugarbaker, Paul H.

Subjects
GRANULOSA cell tumors
Abstract

Granulosa cell tumors of the ovary (GCT) are the most common type of sex cord stromal tumors. Although most of patients are diagnosed at early stage and has favorable 5‐year overall survival rate, 16–23% of GCT ultimately develop recurrent disease. Recurrences are characterized by disseminated peritoneal metastasis. The treatment options include systemic chemotherapy, secondary CRS or palliative localized radiation therapy have not yet standardized due to the rarity of disease. Aggressive CRS followed up by hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to provide benefit in other peritoneal disease but limited data available for recurrent GCT. We have a case of recurrent Adult‐type GCT (AGCT) who was treated with CRS followed by HIPEC with mitomycin C and doxorubicin. The patient has no evidence of recurrence for approximately 11 years. An electronic search of the PubMed database with the following search terms: GCT, HIPEC showed that there were total 21 patients with recurrent GCT treated in seven different studies and 13 of 21 (61.9%) patients had no evidence of disease during follow‐up ranging from 6 to 100 months. Three patients (14.2%) died of the disease. Six studies used cisplatin for HIPEC. At least 76.2% (16 of 21, data not available for five patients) had complete cytoreduction with total 16 cases of perioperative complications but no perioperative mortality was observed. Although further investigation is needed, we propose that CRS and HIPEC can be an effective therapeutic option for recurrent GCT at experienced institutions. [ABSTRACT FROM AUTHOR]

Published
2021
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22. Letters to the Editor.

Author

Dainty, Louis A., Morgan, Shafid A., Parker, Michael E., and Burke, Ronald L.

Subjects
*RABIES, *MEDICAL care
Abstract

A response by the authors of the article "Rabies, Readiness, and Role 1 Medical Care" in a 2013 issue of the journal is presented.

Published
2014

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