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Four strains of Bacillus thuringiensiswere isolated from infections in burn wounds and from water used in the treatment of burn wounds. The strains produced large parasporal inclusion bodies composed of 141, 83, and 81 kDa protoxins. The four strains were tested for insecticidal activity against larvae of Pieris brassicaeand Aedes aegyptibut showed no activity; Vero cell assays for the production of enterotoxins were also negative. Attempts to classify the strains according to flagellar H‐serotype showed them all to be non‐flagellated. Apart from two occupational health accidents that occurred during the handling of highly concentrated B. thuringiensisfluids, this is the first report of B. thuringiensiscausing non‐gastrointestinal clinical infection in immunosuppressed patients.