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I.I. Grishin1, S.Zh. Danelyan2, E.I. Borovkova1, V.A. Roshchina1 1Pirogov Russian National Research Medical University, Moscow, Russian Federation 2City Clinical Hospital No. 40, Moscow, Russian Federation The effect of uterine artery embolization on fertility still remains elusive. Currently, the data on the effect of uterine artery embolization on the ability to conceive, to maintain pregnancy, and to deliver in women with uterine fibroids are scarce. Uterine fibroids are common in sterile women. However, some data suggest that these benign tumors are associated with infertility in 5% to 10% of cases only when other causes of reproductive dysfunction are excluded. Recently, this issue has become particularly important since women tend to get pregnant later. The paper describes clinical case of several successful pregnancy and delivery after uterine artery embolization. The authors conclude that uterine artery embolization in women of reproductive age who want to become pregnant is quite possible. Uterine artery embolization can be applied as an independent treatment for uterine fibroids or in combination with surgery at the first step thus making myomectomy easier. Uterine artery embolization is a highly effective method to restore reproductive function. Keywords: uterine fibroids, uterine artery embolization, pregnancy, delivery, reproduction, fertility. For citation: Grishin I.I., Danelyan S.Zh., Borovkova E.I., Roshchina V.A. Successful pregnancy and delivery in a women after uterine artery embolization: case report. Russian Journal of Woman and Child Health. 2019;2(2):148–150.

The article discusses primary trends in prevention of violent criminality against rights and freedoms of helpless victims. Based on general theoretical methods of analysis and synthesis, generalization, citation, axiomatic methods, the authors come to a conclusion that to affect victimization processes of the most vulnerable part of population, it is required to create an informational basis covering a set of people acknowledged as helpless due to a disease or disability, of senior or minor age, as well as persons living in difficult families as potentially being at risk to be subject to criminal actions. In this connection, the authors believe that in the area of victomolgical protection of vulnerable citizens at the current stage, it is required to improve efficiency of law-enforcement activity in terms of prevention of breaches of social rights of this category of citizens, including rights for victimological rehabilitation, which requires improvement of legal mechanisms envisaging a system of measures for victimological prevention of violent criminality. Maximum possible promulgation of information concerning the number of registered crimes towards helpless victims is a relevant and vital need. First of all, this signifies attention exerted by law-enforcement authorities towards the most vulnerable part of population. Secondly, this forms an irreconcilable attitude of the society towards persons committing such crimes. Thirdly, this creates a basis to improve awareness of helpless persons relative to risks occurring due to their condition and to minimize the distrust syndrome occurring because of a stereotype concerning no possibility or desire of law-enforcement authorities to help them. Moreover, general public will have a complete and objective (rather than fragmentary) understanding covering the entire range of illegal actions committed against such victims.

Purpose: Central nervous system (CNS) tumors are the most common solid malignancies in children worldwide, including in Armenia. The current study aims to analyze epidemiological data, treatment, and outcomes of children and young adults (≤25 years) with CNS tumors in Armenia during the last 26 years., Methods: We collected data from pediatric and young adult patients treated in selected sites in Armenia from 1 st January 1995 to 31 st December 2020. Incidence by sex, age at diagnosis, time from first complaints to diagnosis, histopathology results, treatment strategies, complications, and overall survival (OS) rates were calculated., Results: The multicenter data analysis revealed 149 patients with diagnosed primary CNS tumors over 26 years. Among them, 84 (56.4%) were male. The median age at diagnosis was 7 years (range, 3 months to 25 years), and the median time from the first complaints to diagnosis was 2 months (range, 1 week to 70 months). Medulloblastomas and other embryonal tumors (47), low-grade gliomas (32), and high-grade gliomas (22) were the most commonly diagnosed malignancies. Ependymomas, craniopharyngiomas, germ cell tumors, and other malignancies were observed in 22 patients. For 26 patients, no histopathological or radiological diagnosis was available. Follow-up information was available for 98 (65.8%) patients. The 5-year OS rate for the whole study group was 67.7%., Conclusion: Consistent with international data, embryonal tumors, and gliomas were the most commonly diagnosed CNS malignancies in Armenia. Multimodal treatment was often not available in Armenia during the study period, especially for early cases., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Background: It is known that one of the reasons for the increased incidence of hematological malignancies is caused by the growth of multiple myeloma (MM). Worldwide, approximately 159,985 new cases of MM are diagnosed representing 0.9% of all cancer diagnoses and 106,105 patients will die from MM accounting for 1.1% of all cancer deaths per year. Despite significant advances in the MM treatment the mortality rates are still high. The presented study is the first accurate epidemiological study of ММ in Armenia for the period of 2006-2018., Methods: The initial data for this retrospective cohort survey were derived from ambulance cards, hospitalization journals, and clinical data from the Registry of Blood Diseases at the Yeolyan Hematology Center., Results: Data analysis showed that during 2006-2018 the average annual incidence for the MM was 1.2 per 100,000 population. A significant increase was observed in 2018 compared to 2006, 1.9 vs. 0.7 per 100,000 population. Interestingly, there were no sex differences in the overall MM incidence during the study period. According to the received data, during the period of the 2006-2009 and 2014-2018 the 1-year survival rate for both sexes decreased dramatically from 83 to 64.1% at age group 60 years and below and from 78.5 to 68.1% in group 60 years and over. The 1-year overall survival (OS) for both sexes decreased by 18.9% for patients (≤60 age group) and 10.4% (> 60 age group) in the period of 2006-2009 to the period of 2014-2018., Conclusions: The incidence rates for the MM increased during the analyzed period. Our study showed that males and females in the age group 60 years and below had better 5-year overall survival compared to elder ones and females have better survival., (© 2021. The Author(s).)