1. Prognostic Value of Nonischemic Ringlike Left Ventricular Scar in Patients With Apparently Idiopathic Nonsustained Ventricular Arrhythmias
- Author
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Daniele Muser, Gaetano Nucifora, Maurizio Pieroni, Simon A. Castro, Ruben Casado Arroyo, Shingo Maeda, Daniel A. Benhayon, Ioan Liuba, Mouhannad Sadek, Silvia Magnani, Andres Enriquez, Jackson J. Liang, Biagio Sassone, Benoit Desjardins, Sanjay Dixit, Rajat Deo, Fermin C. Garcia, David J. Callans, David S. Frankel, Joseph B. Selvanayagam, Francis E. Marchlinski, and Pasquale Santangeli
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cardiac gadolinium ,Cardiologie et circulation ,Heart Ventricles ,Arrhythmias ,Magnetic resonance angiography ,NO ,Prognosis ,Physiologie générale ,Physiology (medical) ,Internal medicine ,Humans ,Late gadolinium enhancement ,Medicine ,In patient ,cardiac gadolinium ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,magnetic resonance angiography ,Arrhythmias, Cardiac ,Middle Aged ,Survival Analysis ,Cardiology ,Female ,prognosis ,Cardiology and Cardiovascular Medicine ,Cardiac magnetic resonance ,business ,arrhythmias ,Value (mathematics) - Abstract
Background: Left ventricular (LV) scar on late gadolinium enhancement (LGE) cardiac magnetic resonance has been correlated with life-threatening arrhythmic events in patients with apparently idiopathic ventricular arrhythmias (VAs). We investigated the prognostic significance of a specific LV-LGE phenotype characterized by a ringlike pattern of fibrosis. Methods: A total of 686 patients with apparently idiopathic nonsustained VA underwent contrast-enhanced cardiac magnetic resonance. A ringlike pattern of LV scar was defined as LV subepicardial/midmyocardial LGE involving at least 3 contiguous segments in the same short-axis slice. The end point of the study was time to the composite outcome of all-cause death, resuscitated cardiac arrest because of ventricular fibrillation or hemodynamically unstable ventricular tachycardia and appropriate implantable cardioverter defibrillator therapy. Results: A total of 28 patients (4%) had a ringlike pattern of scar (group A), 78 (11%) had a non-ringlike pattern (group B), and 580 (85%) had normal cardiac magnetic resonance with no LGE (group C). Group A patients were younger compared with groups B and C (median age, 40 vs 52 vs 45 years; P, SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2021
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