52 results on '"Daniel Estève"'
Search Results
2. A disposable plastic compact wrist for smart minimally invasive surgical tools.
- Author
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Frédérick Van Meer, Alain Giraud, Daniel Estève, and Xavier Dollat
- Published
- 2005
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3. 2D Silicon Macro-Force Sensor for Tele-Operated Surgical Instrument.
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Frédérick Van Meer, Daniel Estève, Alain Giraud, and Anne Marie Gué
- Published
- 2004
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4. Ambient Intelligence for Monitoring Alzheimer Patients.
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Walid Bourennane, Yoann Charlon, Fehd Bettahar, Marie Chan, Daniel Estève, and Eric Campo
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- 2013
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5. Smart wearable systems: Current status and future challenges.
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Marie Chan, Daniel Estève, Jean-Yves Fourniols, Christophe Escriba, and Eric Campo
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- 2012
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6. Sex Influences the Genetic Structure of Greenland Halibut in the North Atlantic
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Daniel Estévez‐Barcia, Denis Roy, Mikko Vihtakari, Davíð Gíslason, Martin Lindegren, Asbjørn Christensen, Laura Wheeland, Margaret Treble, Julio Úbeda, Adriana Nogueira, Kevin Hedges, Áki Jarl Láruson, Alejandro Mateos Rivera, Geir Dahle, Jon‐Ivar Westgaard, Bjarki Elvarsson, Lise Helen Ofstad, Elvar H. Hallfredsson, Ole Thomas Albert, Jesper Boje, and Torild Johansen
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adaptation ,genetic sex determination ,population genetics ,Reinhardtius hippoglossoides ,sex‐biasses ,Ecology ,QH540-549.5 - Abstract
ABSTRACT Greenland halibut (Reinhardtius hippoglossoides) is a commercially important species in the North Atlantic whose spatial population structure has not yet been fully determined across its entire range. We genotyped individuals from across the North Atlantic using a subset of informative single nucleotide polymorphic (SNP) markers to assess their usability as a SNP panel. We assessed whether these purportedly structured SNPs had any association with sex. We found several of these loci to be in sex‐determining chromosomes and that their inclusion generated genetic structure mainly in males. The population structure without the sex‐associated SNPs was weak and followed an isolation‐by‐distance pattern, likely with a large regional population on each side of the North Atlantic. We discuss how different sex ratios in the samples and/or an evolving sex‐determination system in this species likely caused the inclusion of sex‐associated loci in the panel. We found suggestive evidence of polymorphisms at sex‐determining chromosomes differentiating males on east and west locations, indicating evolution of the sex‐determination system. These results highlight the importance of documenting sex‐based differences in genetic studies and call for a better understanding of genomic architecture to understand sex‐determination systems across the whole distribution of sexually dimorphic species.
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- 2025
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7. Life expectancy and characterization of capacitive RF MEMS switches.
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Mohamed Matmat, K. Koukos, Fabio Coccetti, T. Idda, Antoine Marty, Christophe Escriba, Jean-Yves Fourniols, and Daniel Estève
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- 2010
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8. Capacitive RF MEMS analytical predictive reliability and lifetime characterization.
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Mohamed Matmat, Fabio Coccetti, Antoine Marty, Robert Plana, Christophe Escriba, Jean-Yves Fourniols, and Daniel Estève
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- 2009
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9. A review of smart homes - Present state and future challenges.
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Marie Chan, Daniel Estève, Christophe Escriba, and Eric Campo
- Published
- 2008
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10. Intégration multicapteur pour un habitat intelligent. Spécifications des détecteurs de présence et perspectives.
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Eric Campo, Marie Chan, Christophe Escriba, S. Bonhomme, and Daniel Estève
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- 2008
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11. Impact of the space environmental conditions on the reliability of a MEMS COTS based system.
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Petra Schmitt, Xavier Lafontan, Francis Pressecq, B. Kurz, Coumar Oudéa, Daniel Estève, Jean-Yves Fourniols, and Henri Camon
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- 2004
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12. L'apprentissage des modes de vie: une base indispensable au développement d'un habitat 'intelligent'.
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Eric Campo, Marie Chan, and Daniel Estève
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- 2003
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13. Application of MEMS behavioral simulation to Physics of Failure (PoF) modeling.
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Petra Schmitt, Francis Pressecq, Xavier Lafontan, Q.-H. Duong, Patrick Pons, Jean Marc Nicot, Coumar Oudéa, Daniel Estève, Jean-Yves Fourniols, and Henri Camon
- Published
- 2003
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14. Twenty-three millisecond electron spin coherence of erbium ions in a natural-abundance crystal
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Marianne Le Dantec, Miloš Rančić, Sen Lin, Eric Billaud, Vishal Ranjan, Daniel Flanigan, Sylvain Bertaina, Thierry Chanelière, Philippe Goldner, Andreas Erb, Ren Bao Liu, Daniel Estève, Denis Vion, Emmanuel Flurin, Patrice Bertet, Université Paris-Saclay, CNRS, CEA, Service de Physique de l’État Condensé, 91191 Gif-sur-Yvette, France, The Chinese University of Hong Kong [Hong Kong], Department of Physics, Columbia University, Columbia University [New York], Institut des Matériaux, de Microélectronique et des Nanosciences de Provence (IM2NP), Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Nanophysique et Semiconducteurs (NPSC), Institut Néel (NEEL), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Recherche de Chimie Paris (IRCP), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ministère de la Culture (MC), Bayerische Akademie der Wissenschaften (BADW), Service de physique de l'état condensé (SPEC - UMR3680), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Quantronics Group (QUANTRONICS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Department of Physics [Hong Kong University of Science and Technology], Hong Kong University of Science and Technology (HKUST), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Nanophysique et Semiconducteurs (NEEL - NPSC), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), ANR-19-CE47-0004,DARKWADOR,Détecteur de photon micro-onde unique à très bas bruit de comptage(2019), and ANR-19-CE47-0011,MIRESPIN,Interfaces microonde spin de terres rares pour le traitement quantique de l'information(2019)
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Quantum Physics ,Multidisciplinary ,Condensed Matter - Mesoscale and Nanoscale Physics ,FOS: Physical sciences ,SciAdv r-articles ,02 engineering and technology ,021001 nanoscience & nanotechnology ,7. Clean energy ,01 natural sciences ,3. Good health ,[PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph] ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,0103 physical sciences ,Physical and Materials Sciences ,Condensed Matter::Strongly Correlated Electrons ,Quantum Physics (quant-ph) ,010306 general physics ,0210 nano-technology ,Research Article ,Applied Physics - Abstract
Description, A scheelite crystal with residual concentration of erbium is cooled down to 10 mK, yielding a record spin coherence time of 23 ms., Erbium ions embedded in crystals have unique properties for quantum information processing, because of their optical transition at 1.5 μm and of the large magnetic moment of their effective spin-1/2 electronic ground state. Most applications of erbium require, however, long electron spin coherence times, and this has so far been missing. Here, by selecting a host matrix with a low nuclear-spin density (CaWO4) and by quenching the spectral diffusion due to residual paramagnetic impurities at millikelvin temperatures, we obtain a 23-ms coherence time on the Er3+ electron spin transition. This is the longest Hahn echo electron spin coherence time measured in a material with a natural abundance of nuclear spins and on a magnetically sensitive transition. Our results establish Er3+:CaWO4 as a potential platform for quantum networks.
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- 2021
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15. Detecting spins by their fluorescence with a microwave photon counter
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Emanuele Albertinale, Léo Balembois, Eric Billaud, Vishal Ranjan, Daniel Flanigan, Thomas Schenkel, Daniel Estève, Denis Vion, Patrice Bertet, and Emmanuel Flurin
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Multidisciplinary - Abstract
Quantum emitters respond to resonant illumination by radiating part of the absorbed energy. A component of this radiation field is phase coherent with the driving tone, whereas another component is incoherent and consists of spontaneously emitted photons, forming the fluorescence signal
- Published
- 2021
16. Elderly daily activity habits or lifestyle in their natural environments.
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Marie Chan, Daniel Estève, and Eric Campo
- Published
- 2011
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17. Si-micromachined 2D force sensor for a laparoscopic instrument.
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Frédérick Van Meer, Daniel Estève, Alain Giraud, and Anne Marie Gué
- Published
- 2004
18. Microcapteur pour la mesure en ligne et en continu de l’encrassement dans les procédés industriels et de traitement de l’eau
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Ali Boukabache, Ludovic Salvagnac, Luc Filladeau, Laurent Auret, Jonathan Crattelet, and Daniel Estève
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Engineering (miscellaneous) ,Instrumentation - Published
- 2011
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19. Concevoir et apprendre, deux expériences homologues en architecture
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Marion Howa and Daniel Estevez
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experience ,transformation ,open design ,critical pedagogy ,non-formal design ,Social Sciences - Abstract
From a pragmatic perspective in architecture, experience is a fundamental structural element of any critical design process. It renders precise observation and the transformation of inhabited environments inseparable and operates outside the scope of normative models in the production of objects. It refers to a singular process of intervention in relation to situations. To explain the critical importance of experience in architecture, the article proposes a comparative analysis between open design practices and critical pedagogy used for training architects. Two case studies are compared : the project for the transformation of the Beutre housing estate near Bordeaux and the Learning From workshop at the Toulouse School of Architecture. The analogical study of these experiential approaches allows us to identify three common elements : the principle of indeterminacy, open tools, and restructuring games used during the design process. The aim of this dialogue between learning and designing is to identify non-destructive methods based on transformation that can be applied to architecture and teaching.
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- 2023
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20. Integrating pheromonal and spatial information in the amygdalo-hippocampal network
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María Villafranca-Faus, Manuel Esteban Vila-Martín, Daniel Esteve, Esteban Merino, Anna Teruel-Sanchis, Ana Cervera-Ferri, Joana Martínez-Ricós, Ana Lloret, Enrique Lanuza, and Vicent Teruel-Martí
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Science - Abstract
Male and female mice need to generate spatial maps that integrate vomeronasal signals of territory owners in the hippocampus-dependent memory. The authors show that vomeronasal information influences learning-related activity in the hippocampus via the amygdaloid PMCo, lateral entorhinal cortex, and dorsal CA1.
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- 2021
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21. Negative frequency‐dependent selection maintains shell banding polymorphisms in two marine snails (Littorina fabalis and Littorina saxatilis)
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Daniel Estévez, Juan Galindo, and Emilio Rolán‐Alvarez
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apostatic selection ,camouflage ,color polymorphism ,frequency‐dependent natural selection ,genetic drift ,Littorina ,Ecology ,QH540-549.5 - Abstract
Abstract The presence of shell bands is common in gastropods. Both the marine snails Littorina fabalis and Lttorina saxatilis are polymorphic for this trait. Such polymorphism would be expected to be lost by the action of genetic drift or directional selection, but it appears to be widespread at relatively constant frequencies. This suggests it is maintained by balancing selection on the trait or on a genetically linked trait. Using long time series of empirical data, we compared potential effects of genetic drift and negative frequency‐dependent selection (NFDS) in the two species. The contribution of genetic drift to changes in the frequency of bands in L. fabalis was estimated using the effective population size estimated from microsatellite data, while the effect of genetic drift in L. saxatilis was derived from previously published study. Frequency‐dependent selection was assessed by comparing the cross‐product estimator of fitness with the frequency of the polymorphism across years using a regression analysis. Both studied species showed patterns of NFDS. In addition, in L. fabalis, contributions from genetic drift could explain some of the changes in banding frequency. Overdominance and heterogeneous selection did not fit well to our data. The possible biological explanations resulting in the maintenance of the banding polymorphism are discussed.
- Published
- 2021
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22. Vers des machines quantiques
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Daniel Estève and Michel Dévoret
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- 2003
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23. Design and flight results of the VHF/UHF communication system of Longjiang lunar microsatellites
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Mingchuan Wei, Chaoran Hu, Daniel Estévez, Mier Tai, Yuhao Zhao, Jiahe Huang, Cees Bassa, Tammo Jan Dijkema, Xibin Cao, and Feng Wang
- Subjects
Science - Abstract
Satellites with amateur radio communication capabilities have not been operated in lunar orbit before. Here, the authors present the design and performance of a VHF/UHF software-defined radio developed for and tested on lunar microsatellites.
- Published
- 2020
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24. Microsystèmes
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Daniel ESTÈVE and Jean SIMONNE
- Published
- 2000
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25. L’ERC (European Research Council) - Une chance et un défi pour les chercheurs et les organismes de recherche
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Daniel Estève
- Subjects
General Medicine - Abstract
L’ERC est une nouvelle institution europeenne, concue et controlee par des chercheurs, dans le but de soutenir les meilleurs d’entre eux, en Europe quelle que soit la discipline, et sur le seul critere de l’excellence scientifique.
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- 2007
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26. Is Oxidative Stress the Link Between Cerebral Small Vessel Disease, Sleep Disruption, and Oligodendrocyte Dysfunction in the Onset of Alzheimer’s Disease?
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Ana Lloret, Daniel Esteve, Maria Angeles Lloret, Paloma Monllor, Begoña López, José Luis León, and Ana Cervera-Ferri
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demyelination ,sleep dysfunction ,blood-brain barrier permeability ,ApoE4 and AD risk ,vessel dysfunction ,oligodendrocyte precursor cell ,Physiology ,QP1-981 - Abstract
Oxidative stress is an early occurrence in the development of Alzheimer’s disease (AD) and one of its proposed etiologic hypotheses. There is sufficient experimental evidence supporting the theory that impaired antioxidant enzymatic activity and increased formation of reactive oxygen species (ROS) take place in this disease. However, the antioxidant treatments fail to stop its advancement. Its multifactorial condition and the diverse toxicological cascades that can be initiated by ROS could possibly explain this failure. Recently, it has been suggested that cerebral small vessel disease (CSVD) contributes to the onset of AD. Oxidative stress is a central hallmark of CSVD and is depicted as an early causative factor. Moreover, data from various epidemiological and clinicopathological studies have indicated a relationship between CSVD and AD where endothelial cells are a source of oxidative stress. These cells are also closely related to oligodendrocytes, which are, in particular, sensitive to oxidation and lead to myelination being compromised. The sleep/wake cycle is another important control in the proliferation, migration, and differentiation of oligodendrocytes, and sleep loss reduces myelin thickness. Moreover, sleep plays a crucial role in resistance against CSVD, and poor sleep quality increases the silent markers of this vascular disease. Sleep disruption is another early occurrence in AD and is related to an increase in oxidative stress. In this study, the relationship between CSVD, oligodendrocyte dysfunction, and sleep disorders is discussed while focusing on oxidative stress as a common occurrence and its possible role in the onset of AD.
- Published
- 2021
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27. Lurasidone: Ten Years Treating Adults with Bipolar Depression
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Margarida Albuquerque, João Facucho-Oliveira, Daniel Esteves-Sousa, Nuno Moura, Daniel Neto, and Pedro Cintra
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Adult ,Antipsychotic Agents/therapeutic use ,Bipolar Disorder/drug therapy ,Lurasidone Hydrochloride/ therapeutic use ,Psychiatry ,RC435-571 ,Psychology ,BF1-990 - Abstract
Lurasidone is an atypical antipsychotic approved in 2010 in Canada and in the USA for the treatment of adults with schizophrenia or bipolar type I disorder. In 2014 it was approved in the European Union for the treatment of patients with 13 years‑old or older, with schizophrenia. Lurasidone is a benzisothiazole derivative with a binding profile that makes it an antidepressant candidate with a low metabolic impact. In patients with bipolar disorder, depressive episodes tend to be present for the majority of the time and are difficult to treat, as shown in multiple surveys indicating that more than three quarters of patients with bipolar depression receive at least two pharmaceutical drugs and more than one third receive three or more. Some relevant international guidelines include different first‑line options in the treatment of bipolar depression, among which is lurasidone. Considering the difficulties in treating depressive episodes in bipolar disorder, the EU marketing authorization limiting the use of lurasidone in schizophrenia only and the expectable commercialization in Portugal by 2021, we aim to review the literature regarding the efficacy and advantages of lurasidone for depressive episodes of bipolar disorder and to discuss the usefulness of approving this medication as an alternative treatment approach.
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- 2021
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28. Esketamine in Treatment Resistant Depression: The Way to Remission
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João Facucho-Oliveira, Daniel Esteves-Sousa, Bruno Prates, Rui Neves, and Pedro Varandas
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Antidepressive Agents ,Depressive Disorder, Major/drug therapy ,Depressive Disorder, Treatment‑Resistant/ drug therapy ,Esketamine/administration & dosage ,Psychiatry ,RC435-571 ,Psychology ,BF1-990 - Abstract
Major depressive disorder affects an estimate of 5% of the population with nearly 1‑third of patients failing to achieve remission with conventional pharmacological treatment. Esketamine, a novel rapid‑acting antidepressant, with a noncompetitive antagonism on N‑methyl‑D‑Aspartate receptor, have been recently approved by Food and Drug Administration (FDA) and European Medicines Agency (EMA) for treatment‑resistant depression. Here, we report a clinical case of a 42‑year‑old Caucasian woman who endured many years with severe depressive symptoms and high functional impairment. Previous treatments included cognitive behavioral therapy, numerous pharmacological trials with antidepressants and augmentation agents, and neurostimulation approaches. Upon treatment with esketamine, the patient presented remarkable clinical recovery. Psychometric assessments determined an acute reduction on the MADRS score after 1 week and progressive recovery of the depressive symptoms on the following weeks. Likewise, PHQ‑9 scale assessments, evaluating the relative frequency of depressive symptoms. and the Sheehan scale, assessing functional recovery, also determined a pronounced symptomatic relief.
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- 2021
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29. Mate Choice Contributes to the Maintenance of Shell Color Polymorphism in a Marine Snail via Frequency-Dependent Sexual Selection
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Daniel Estévez, Eugene Kozminsky, Antonio Carvajal-Rodríguez, Armando Caballero, Rui Faria, Juan Galindo, and Emilio Rolán-Alvarez
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mate choice ,mate competition ,Littorina fabalis ,inbreeding effect ,genetic drift ,fitness components ,Science ,General. Including nature conservation, geographical distribution ,QH1-199.5 - Abstract
Natural color polymorphisms are widespread across animal species and usually have a simple genetic basis. This makes them an ideal system to study the evolutionary mechanisms responsible for maintaining biodiversity. In some populations of the intertidal snail Littorina fabalis, variation in shell color has remained stable for years, but the mechanisms responsible are unknown. Previous studies suggest that this stability could be caused by frequency-dependent sexual selection, but this hypothesis has not been tested. We analyzed shell color polymorphism in mating pairs and surrounding unmated individuals in two different populations of L. fabalis to estimate sexual fitness for color, as well as assortative mating. The estimated effective population size from neutral markers allowed us to disregard genetic drift as the main source of color frequency changes across generations. Shell color frequency was significantly correlated with sexual fitness showing a pattern of negative frequency dependent selection with high disassortative mating for color. The results suggested a contribution of male mate choice to maintain the polymorphism. Finally, the implementation of a multi-model inference approach based on information theory allowed us to test for the relative contribution of mate choice and mate competition to explain the maintenance of color polymorphism in this snail species.
- Published
- 2020
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30. Les microcapteurs, composants-clés de l'intégration des systèmes
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Daniel Estève
- Subjects
Electrical and Electronic Engineering - Published
- 2001
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31. Avant-propos
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Daniel Estève
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General Physics and Astronomy ,General Chemistry - Published
- 1999
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32. Quantum Entanglement and Information Processing : Lecture Notes of the Les Houches Summer School 2003
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Daniel Esteve, Jean-Michel Raimond, Jean Dalibard, Daniel Esteve, Jean-Michel Raimond, and Jean Dalibard
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- Quantum theory--Data processing--Congresses, Mesoscopic phenomena (Physics)--Congresses, Quantum optics--Congresses
- Abstract
It has been recognised recently that the strange features of the quantum world could be used for new information transmission or processing functions such as quantum cryptography or, more ambitiously, quantum computing. These fascinating perspectives renewed the interest in fundamental quantum properties and lead to important theoretical advances, such as quantum algorithms and quantum error correction codes. On the experimental side, remarkable advances have been achieved in quantum optics, solid state physics or nuclear magnetic resonance. This book presents the lecture notes of the Les Houches Summer School on'Quantum entanglement and information processing'. Following the long tradition of the les Houches schools, it provides a comprehensive and pedagogical approach of the whole field, written by renowned specialists.One major goal of this book is to establish connections between the communities of quantum optics and of quantum electronic devices working in the area of quantum computing. When two communities share the same goals, the universality of physics unavoidably leads to similar developments. However, the communication barrier is often high, and few physicists are able to overcome it. This school has contributed to bridge the existing gap between communities, for the benefit of the future actors in the field of quantum computing. The book thus combines introductory chapters, providing the reader with a sufficiently wide theoretical framework in quantum information, quantum optics and quantum circuits physics, with more specialized presentations of recent theoretical and experimental advances in the field. This structure makes the book accessible to any graduate student having a good knowledge of basic quantum mechanics, and extremely useful to researchers.·Covers quantum optics, solid state physics and NMR implementations·Pedagogical approach combining introductory lectures and advanced chapters·Written by leading experts in the field·Accessible to all graduate students with a basic knowledge of quantum mechanics
- Published
- 2004
33. Single tooth morse taper implant placement and restoration immediately after extraction
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Fernando Santos CAUDURO, Daniela Nascimento SILVA, Rogério Belle de OLIVEIRA, Márjorie das Posses BRIDI, Daniel Esteves CAUDURO, and Salete Maria PRETTO
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dental implants ,mouth rehabilitation ,osseointegration ,Dentistry ,RK1-715 - Abstract
Objective: to analyze aesthetic and functional outcomes of the rehabilitation of single tooth morse taper implant restoration with single crown prosthesis immediately after tooth extraction. Methods: Retrospective longitudinal clinical study of 57 patients submitted to an oral rehabilitation protocol with morse taper (Ankylos® Classic) dental implants, without performing incision, grafts nor suture, followed by the placement of a provisional prosthesis immediately after tooth removal in the anterior maxillary region. The pre-and post-operative clinical data (alveolar bone contour at vestibular aspect, soft tissue contour at cervical aspect and papillae level) and postoperative radiographic findings (bone height / implant ratio) were submitted to descriptive statistics (mean and standard deviation) and Fisher’s Exact Test. Results: the implant success rate was 98.25%. The alveolar bone vestibular aspect was maintained in 69.6% of the cases. There was no soft tissue retraction on the cervical aspect and the papillae height was preserved in 89.3% of the cases.The bone level remained above the implant neck in 92.8% of the cases. There was no significant association between implant diameter and soft tissue retraction (p = 0.910) or retraction of the interproximal papilla (p = 0.148) or resorption of the alveolar bone crest (p = 0.610). Conclusion: This protocol is characterized by the application of minimally traumatic techniques, reducing rehabilitation time and offering positive aesthetic and functional results.
- Published
- 2019
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34. Obesity as a Risk Factor for Alzheimer’s Disease: Implication of Leptin and Glutamate
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Ana Lloret, Paloma Monllor, Daniel Esteve, Ana Cervera-Ferri, and Maria-Angeles Lloret
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leptin-resistance ,dementia ,overweight ,excitotoxicity ,LTP ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Obesity is known to induce leptin and insulin resistance. Leptin is a peptide hormone synthesized in adipose tissue that mainly regulates food intake. It has been shown that insulin stimulates the production of leptin when adipocytes are exposed to glucose to encourage satiety; while leptin, via a negative feedback, decreases the insulin release and enhances tissue sensitivity to it, leading to glucose uptake for energy utilization or storage. Therefore, resistance to insulin is closely related to leptin resistance. Obesity in middle age has also been related to Alzheimer’s disease (AD). In recent years, the relation between impaired leptin signaling pathway and the onset of AD has been studied. In all this context the role of the blood brain barrier (BBB) is crucial. Slow excitotoxicity happens in AD due to an excess of the neurotransmitter glutamate. Since leptin has been shown to regulate N-methyl-D-aspartate (NMDA) receptors, we want to review the link between these pathological pathways, and how they are affected by other AD triggering factors and its role in the onset of AD.
- Published
- 2019
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35. Complexity-entropy analysis at different levels of organisation in written language.
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Ernesto Estevez-Rams, Ania Mesa-Rodriguez, and Daniel Estevez-Moya
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Medicine ,Science - Abstract
Written language is complex. A written text can be considered an attempt to convey a meaningful message which ends up being constrained by language rules, context dependence and highly redundant in its use of resources. Despite all these constraints, unpredictability is an essential element of natural language. Here we present the use of entropic measures to assert the balance between predictability and surprise in written text. In short, it is possible to measure innovation and context preservation in a document. It is shown that this can also be done at the different levels of organization of a text. The type of analysis presented is reasonably general, and can also be used to analyze the same balance in other complex messages such as DNA, where a hierarchy of organizational levels are known to exist.
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- 2019
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36. Product and Project Co-design: what do system engineering standards recommend ?
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claude baron, Marc Zolghadri, Daniel Estève, Laurent Geneste, Michel Aldanondo, Élise Vareilles, Zolghadri, Marc, and Springer
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Model Driven Engineering ,[SPI] Engineering Sciences [physics] ,Co-design ,product design ,System Engineering ,project organization - Abstract
Industries have to design and produce performing and reliable systems. Nevertheless, designers suffer from the diversity of methods, which are not really adequate to their needs. Authors highlight the interactions between product and project design, often treated either independently or sequentially. They study the organisation of the exchanges between these two processes and propose a methodology with regard to the standards of System Engineering and the recommendations of Model Driven Engineering (MDE), in the context of what is called the 'co-design' paradigm.
37. How a close association of System Design, Technical Management and Acquisition & Supply processes can improve system design engineering ?
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claude baron, Marc Zolghadri, Michel Aldanondo, Élise Vareilles, Daniel Estève, Laurent Geneste, Guillaume Auriol, Laboratoire de l'intégration, du matériau au système (IMS), Université Sciences et Technologies - Bordeaux 1-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Étude des Systèmes Informatiques et Automatiques (LESIA-INSA), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), and Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)
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Model Driven Engineering ,[SPI]Engineering Sciences [physics] ,product design ,co-design ,System Engineering ,project organization - Abstract
Industries have to design and produce performing and reliable systems. Nevertheless, designers suffer from the diversity of methods, which are not really adequate to their needs. Authors highlight the interactions between processes involved into the global design process, and focus on the product and project design processes, often treated either independently or sequentially. They study the organisation of the exchanges between these two processes and propose a methodology with regard to the standards of System Engineering and the recommendations of Model Driven Engineering (MDE), in the context of what is called the 'co-design' paradigm. Finally, this study is extended to the design of network of partners process also.
38. The quantum technologies roadmap: a European community view
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Antonio Acín, Immanuel Bloch, Harry Buhrman, Tommaso Calarco, Christopher Eichler, Jens Eisert, Daniel Esteve, Nicolas Gisin, Steffen J Glaser, Fedor Jelezko, Stefan Kuhr, Maciej Lewenstein, Max F Riedel, Piet O Schmidt, Rob Thew, Andreas Wallraff, Ian Walmsley, and Frank K Wilhelm
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quantum theory ,quantum coomputing ,quantum simulation ,quantum sensing ,quantum communication ,quantum technologies ,Science ,Physics ,QC1-999 - Abstract
Within the last two decades, quantum technologies (QT) have made tremendous progress, moving from Nobel Prize award-winning experiments on quantum physics (1997: Chu, Cohen-Tanoudji, Phillips; 2001: Cornell, Ketterle, Wieman; 2005: Hall, Hänsch-, Glauber; 2012: Haroche, Wineland) into a cross-disciplinary field of applied research. Technologies are being developed now that explicitly address individual quantum states and make use of the ‘strange’ quantum properties, such as superposition and entanglement. The field comprises four domains: quantum communication, where individual or entangled photons are used to transmit data in a provably secure way; quantum simulation, where well-controlled quantum systems are used to reproduce the behaviour of other, less accessible quantum systems; quantum computation, which employs quantum effects to dramatically speed up certain calculations, such as number factoring; and quantum sensing and metrology, where the high sensitivity of coherent quantum systems to external perturbations is exploited to enhance the performance of measurements of physical quantities. In Europe, the QT community has profited from several EC funded coordination projects, which, among other things, have coordinated the creation of a 150-page QT Roadmap ( http://qurope.eu/h2020/qtflagship/roadmap2016 ). This article presents an updated summary of this roadmap.
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- 2018
- Full Text
- View/download PDF
39. A Resazurin Based Bio Sensor for Detection of Organic Pollutants in Water
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Amani Migaou, Anne-Marie Gue, Marie-Charline Blatche, Daniel Esteve, and Ali Boukabache
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microsystem ,organic pollutants detection ,water analysis ,General Works - Abstract
With the objective of water analysis, a microsystem was developed, by using Resazurin molecule as an indirect bio sensor. The detection principle consists to monitor optically the oxygen consumption of E. Coli bacteria towards their metabolism in presence of organic pollutants. Thus, aiming on Glucose detection, a concentration-dependent inhibition effect on oxygen consumption rate was evidenced in the [0–0.41 mM] range of organic pollutants.
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- 2017
- Full Text
- View/download PDF
40. Magnetic resonance of a single electron spin and its magnetic environment by photon counting
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Balembois, Léo, Service de physique de l'état condensé (SPEC - UMR3680), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, Daniel Estève, Emmanuel Flurin, and Patrice Bertet
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[PHYS.COND.CM-S]Physics [physics]/Condensed Matter [cond-mat]/Superconductivity [cond-mat.supr-con] ,Résonance paramagnétique électronique ,[PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph] ,Electron spin resonance ,Qubit ,Circuits supraconducteurs ,Superconducting circuits - Abstract
Magnetic resonance is a branch of science that aims to detect spins via their absorption and emission of electromagnetic radiation. There are two sub-branches : Nuclear Magnetic Resonance (NMR), which applies to atomic spins, and Electronic Paramagnetic Resonance (EPR), which applies to unpaired electron spins. In both cases, commercial instruments are limited to measuring large ensembles of spins and only provide averages of their collective response. In this thesis, we perform EPR of individual Erbium ions inserted in a scheelite crystal using a new detec-tion method based on the microwave fluorescence emitted by the spins during their relaxation. To promote photon emission, the spins are coupled to a superconducting resonator with a small mode volume and low losses, generating a Purcell effect. The output of the resonator is connected to a microwave photon detector based on a superconducting qubit and a 4-wave micing. The high sensitivity of this detector S = 10⁻²² W/√Hz is one of the keys to the success of this experiment. Our method is applicable to all types of paramagnetic impurities without requiring an optical transition or a large coherence time. We measure the characteristics of several individual spins, the results vary strongly from one spin to another, highlighting the inhomogeneity of their electromagnetic environments. The coherence times reach several milliseconds and are radiatively limited. Finally, we perform an experiment to probe the magnetic environment of a particular impurity using a dynamic decoupling sequence. The resonance signal allows us to demonstrate the presence of ¹⁸³W nuclear spin. We finally make some preliminary hypotheses on their arrangement around the erbium ion studied.; La résonance magnétique est une branche de la science qui vise à détecter les spins via leur absorption et émission de rayonnement électromagnétique. On distingue deux sous-branches : la Résonance Magnétique Nucléaire (RMN) qui s’applique aux spins atomiques et la Résonance Paramagnétique Electronique (RPE) qui s’applique aux spins électroniques non appariés. Dans les deux cas, les appareils commerciaux sont limités à la mesure de vastes ensembles de spins et ne fournissent que des moyennes de leur réponse collective. Dans cette thèse, nous réalisons la RPE d’ion Erbium individuels insérés dans un cristald e scheelite en utilisant une nouvelle méthode de détection basée sur la fluorescence micro-onde émise par les spins pendant leur relaxation. Pour favoriser l’émission de photon, les spins sont couplés à un résonateur supraconducteur ayant un petit volume de mode et de faibles pertes, générant un effet Purcell. La sortie du résonateur est connectée à un compteur de photon micro-onde basé sur un qubit supraconducteur et un mélange à 4 ondes. La grande sensibilité de ce détecteur S = 10⁻²² W/√Hz est une des clés de la réussite de cette expérience. Notre méthode s’applique à tous types d’impuretés paramagnétiques sans nécessiter une transition optique ni un grand temps de cohérence. Nous mesurons les caractéristiques de plusieurs spins individuels, les résultats varient fortement d’un spin à l’autre, mettant en avant l’inhomogénéité de leurs environnements électromagnétiques. Les temps de cohérence atteignent plusieurs millisecondes et sont limités radiativement. Finalement, nous réalisons une expérience visant à sonder l’environnement magnétique d’une impureté particulière grâce à une séquence de découplage dynamique. Le signal à résonance nous permet de mettre en évidence la présence de spin nucléaire de ¹⁸³W. Nous émettons finalement quelques hypothèses préliminaires sur leur disposition autour de l’ion erbium étudié.
- Published
- 2023
41. Quantum Zeno Dynamics in 3D Circuit-QED
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Júlíusson, Kristinn, Service de physique de l'état condensé (SPEC - UMR3680), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris VI, Daniel Estève, Denis Vion, and STAR, ABES
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Dynamique quantique ,[PHYS.COND.CM-S]Physics [physics]/Condensed Matter [cond-mat]/Superconductivity [cond-mat.supr-con] ,Électronique quantique ,Quantum Zeno ,Circuit supraconducteur ,Superconducting circuit ,Bit quantique ,[PHYS.COND.CM-S] Physics [physics]/Condensed Matter [cond-mat]/Superconductivity [cond-mat.supr-con] ,Jonction Josephson ,Circuit-QED ,Effet Zénon quantique - Abstract
This thesis presents experimental work aimed at observing the quantum Zeno dynamics (QZD) in 3D circuit-QED, where an artificial atom, consisting of a superconducting circuit called a transmon, is coupled to the electric field of a microwave cavity resonator. The transmon and resonator energy levels are aligned in a novel way enabling the manipulation of individual Fock states of the cavity, while minimizing its transmon-induced Kerr non-linearity. We induce the QZD by displacing classically the cavity field while continuously driving strongly a transmon transition specific to a particular Fock state, which keeps this Fock state population at zero. The QZD is then observed by measuring the Wigner function of the fields at regular time intervals, either by Wigner tomography or standard quantum tomography and reconstruction of the density matrix. We observe three examples of QZD, and analyze the observed decoherence with the help of quantum simulations of the system., Cette thèse présente le travail expérimental effectué pour observer la dynamique quantique de Zénon (QZD) dans une architecture 'circuit-QED' tridimentionnelle fonctionnant à très basse température. Dans cette architecture, un circuit supraconducteur de type transmon, jouant le rôle d'un atome artificiel, est couplé au champ électromagnétique d'une cavité microonde. Les niveaux d'énergie de l'atome et de la cavité sont alignés d'une nouvelle manière, afin de manipuler les états de Fock individuels de la cavité, tout en minimisant sa non-linearité Kerr induite par le transmon. La dynamique Zénon est obtenue en pilotant classiquement le champ de la cavité, tout en excitant fortement une transition inter-niveaux d'énergie du transmon, conditionnée à un état de Fock particulier. Ce forcage maintient la population de l'état de Fock à zéro, et conduit à la dynamique Zeno. Cette dynamique est observée par mesure de sa fonction de Wigner à intervalles de temps réguliers, soit par tomographie de Wigner, soit par tomographie quantique standard et reconstruction de la matrice densité. Nous observons trois exemples de QZD, et analysons la décohérence observée à l'aide simulations quantiques du système.
- Published
- 2016
42. Design and prototyping of a complete system for grain monitoring in storage silos
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Bettahar, Fehd, Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Université Toulouse le Mirail - Toulouse II, Éric Campo, Daniel Estève, Équipe Instrumentation embarquée et systèmes de surveillance intelligents ( LAAS-S4M ), Laboratoire d'analyse et d'architecture des systèmes [Toulouse] ( LAAS ), Centre National de la Recherche Scientifique ( CNRS ) -Université Toulouse III - Paul Sabatier ( UPS ), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse ( INSA Toulouse ), Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Institut National Polytechnique [Toulouse] ( INP ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Toulouse III - Paul Sabatier ( UPS ), Institut National des Sciences Appliquées ( INSA ) -Institut National des Sciences Appliquées ( INSA ) -Institut National Polytechnique [Toulouse] ( INP ), UNIVERSITE DE TOULOUSE II, Eric Campo, Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Université de Toulouse (UT)
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Aide à la décision ,Multisensory monitoring system ,Behavioral model ,Decision support ,[SPI.TRON]Engineering Sciences [physics]/Electronics ,Protection de céréales ,Capteurs répartis ,Système de surveillance ,Automated learning ,[ INFO.INFO-AU ] Computer Science [cs]/Automatic Control Engineering ,Cereal protection ,Modèle comportemental ,[ INFO.INFO-SY ] Computer Science [cs]/Systems and Control [cs.SY] ,Monitoring system ,Distributed sensors ,Système de surveillance multi-sensorielle - Abstract
This thesis deals with new monitoring technologies applied to grain storage in silos. Since the first sedentary groups, cereals have been representing the main population and livestock’s staple food. Harvests are seasonal and their storage is therefore a vital necessity for the world’s population that will count 9 billion in 2050 compared to 7.3 billion today. In this problematic around monitoring of silos, insects represent the first grain postharvest pest causing considerable losses, in some cases up to 10% of the production. Several techniques and methods have been developed and implemented in order to face the danger of these pests. The most common method is the use of synthetic chemical insecticides, which have an obvious negative effect on both human health and the environment. This work is part of a cooperative program named ECOSILO, whose main objective is to design and prototype ecological alternatives to the systematic and massive use of insecticides. This is therefore a largely multidisciplinary approach, in which we were in charge to conceptualize a comprehensive monitoring system to: provide an earlier detection of infestations and put in place an automatic control of the attractive and insecticides diffusion. Our proposal is based on a logic of integrated pest management (IPM) and focuses on the prevention and early detection of possible infestations, in order to preserve stocks and avoid reaching high level of economic loss. Its fundamental originality lies in the proposition of a predictive model of the infestation development, which consists of coupling a thermal model of the silo with a biological model describing the insect’s growth. It is thus possible, with the support of additional meteorological data, to anticipate the development of insects and to initiate preventive alarms. This solution is accompanied by more specific electronic and computer monitoring developments in silos which are: A detection system at the entrance of silos; A supervision of the top of the hottest heap of grain; A monitoring of the heap of grain in its entire height. These developments are implementing multiple detection modes (temperature, humidity, acoustic probe, CO2). All these technical contributions are incorporated in the form of a comprehensive monitoring system equipped with a user interface that meets the requirements of the overall project ECOSILO. The functional checks have been performed in the laboratory and on real site. We conclude on the perspectives opened by this work.; Cette thèse traite des nouvelles technologies de surveillance appliquées au stockage des grains en silos. Les céréales représentent depuis les premiers regroupements sédentaires l’aliment principal pour l’Homme comme pour le bétail. Les récoltes sont saisonnières et leur stockage est donc une nécessité vitale pour une population mondiale qui compte actuellement 7,3 Mds d'habitants et qui en comptera 9 Mds en 2050. Dans cette problématique autour de la surveillance des silos, les insectes représentent les premiers ravageurs de grain après récolte, ce qui entraîne des pertes considérables pouvant atteindre dans certains cas jusqu’à 10% de la production. Plusieurs techniques et méthodes ont été développées et mises en pratique afin de faire face au danger que représentent ces ravageurs. La méthode la plus répandue est l’utilisation des insecticides chimiques de synthèse dont la dangerosité, impactant tant sur la santé humaine que sur l'environnement, est plus qu'évidente. Ce travail de thèse s'inscrit dans un programme coopératif, nommé ECOSILO, dont l'objectif majeur est de concevoir et de prototyper des solutions alternatives écologiques à l'utilisation systématique et massive de produits insecticides. Il s'agit donc d'une démarche largement pluridisciplinaire dans laquelle nous avons eu en charge d'imaginer un système complet de surveillance : détection au plus tôt des infestations et commande automatique de la diffusion d'attractifs puis d'insecticides. Notre proposition est fondée sur une logique de protection intégrée et privilégie la prévention et la détection précoce d'éventuelles infestations, ce afin de préserver les stocks et d'éviter d'atteindre un stade de perte économique trop élevé. Son originalité fondamentale réside dans la proposition d'un modèle prédictif du développement de l'infestation qui consiste à coupler un modèle thermique du silo avec un modèle biologique décrivant la croissance des insectes. Il est ainsi possible, avec l'appui de données complémentaires météorologiques, d'anticiper le développement des insectes et de lancer des alarmes préventives. Cette solution est accompagnée de développements électroniques et informatiques plus spécifiques de la surveillance continue des silos : un système de détection à l'entrée des silos ; une surveillance sur la partie haute du tas de grain la plus chaude ; une surveillance du tas de grains dans toute sa hauteur. Ces développements mettent en oeuvre des modes de détections multiples (température, humidité, sonde acoustique, CO2). Toutes ces contributions techniques sont intégrées sous la forme d'un système complet de surveillance équipé d'une interface utilisateurs qui répond aux exigences du projet global ECOSILO. Les vérifications fonctionnelles ont été réalisées en laboratoire et sur site réel. Nous concluons sur les perspectives ouvertes par ce travail.
- Published
- 2016
43. Design, fabrication and test of a four superconducting quantum-bit processor
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Schmitt, Vivien, STAR, ABES, Service de physique de l'état condensé (SPEC - UMR3680), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris VI, and Daniel Estève
- Subjects
Computer Science::Emerging Technologies ,[PHYS.PHYS]Physics [physics]/Physics [physics] ,Supraconducteur ,Transmon ,[PHYS.PHYS] Physics [physics]/Physics [physics] ,Quantum Physics ,Qubit ,Superconductor ,Quantique ,Processeur ,Multiplexage ,Multiplexing - Abstract
This thesis presents our effort to design, fabricate and test a simple 4-Josephson qubit processor with scalability potential. The qubits are frequency tunable and are coupled to a shared coupling bus able to implement iSwap two-qubit gates on any pair of qubits. Each qubit is fitted with its own readout made of a Josephson bifurcation amplifier (JBA). The operation principle of the processor, the choice of parameters, the microwave layout design, as well as the fabrication processes are described. A first experiment demonstrates the simultaneous high-fidelity readout of all the qubits by frequency multiplexing of the JBA signals. A second one tests the two-qubit iSwap gate of the processor, the fidelity of which happens to be limited by the intrinsic qubit decoherence., Cette thèse présente le travail de conception, de fabrication et de test d'un processor à 4 qubits Josephson, avec un souci d’évolutivité. Les qubits ont une fréquence réglable et sont tous couplés à un unique bus de couplage, afin d’implémenter la porte à deux qubits iSWAP, sur n’importe quelle paire d'entre eux. Chaque qubit est aussi équipé d’un amplificateur Josephson à bifurcation (JBA). Le principe du processeur, le choix des paramètres, le design micro-onde ainsi que la fabrication sont décrits. Une première expérience montre la lecture simultanée, haute-fidélité et en un coup de tous les qubits, par une technique de multiplexage fréquentiel des signaux de lecture. Une seconde teste la fidélité de la porte à deux qubits iSWAP, qui apparait limitée par la décohérence intrinsèque des qubits.
- Published
- 2015
44. Corrélations quantiques et structures causales
- Author
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Ibnouhsein, Mohamed Issam, Laboratoire des Recherches sur les Sciences de la Matière (LRSM), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Université Paris Sud - Paris XI, Daniel Estève, and Alexei Grinbaum
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Entropy of entanglement ,Relativistic quantum field theory ,Quantum information ,Théorie quantique relativiste des champs ,Localization scheme ,Théorie quantique ,Quantum computing ,Informatique quantique ,Information quantique ,Entropie d'intrication ,Closed timelike curves ,Schéma de localisation ,Poincaré invariance ,[PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph] ,Quantum theory ,Causal order ,Invariance de Poincaré ,Ordre causal ,Courbes de type temps fermées - Abstract
Recent works in foundations of quantum (field) theory and relativistic quantum information try to better grasp the interplay between the structure of quantum correlations and the constraints imposed by causality on physical operations. Chapter 1 is dedicated to the study of the conceptual implications of quantum nonlocality, a concept that subsumes that of entanglement in a certain way. We detail the recent information-theoretic approaches to understanding the structure of nonlocal correlations, and the issues the latter raise concerning the ability of local observers to isolate a system from its environment. Chapter 2 reviews in what sense imposing Poincaré invariance affects entanglement detection and quantification procedures. This invariance ultimately forces a description of all quantum systems within the framework of quantum field theory, which leads to the impossibility of localized finite-energy states and to the divergence of all entanglement measures for local observers. We provide a solution to these two problems by showing that there exists a generic equivalence between a finite spatial resolution of the measurement apparatus and the exclusion of high-energy degrees of freedom from the definition of the observed system. This equivalence allows for an epistemic interpretation of the standard quantum formalism describing nonrelativistic localized systems and their correlations, hence a clarification of the origin of the finite measures of entanglement between such systems. Chapter 3 presents a recent theoretical framework that predicts the existence of correlations with indefinite causal order. In analogy to the information-theoretic approaches to nonlocal correlations, we introduce some principles that constrain the structure of such correlations, which is a first step toward a clear understanding of their physical origin.; Les travaux récents en fondements de la théorie quantique (des champs) et en information quantique relativiste tentent de mieux comprendre les effets des contraintes de causalité imposées aux opérations physiques sur la structure des corrélations quantiques. Le premier chapitre de cette thèse est consacré à l'étude des implications conceptuelles de la non-localité quantique, notion qui englobe celle d'intrication dans un sens précis. Nous détaillons comment les récentes approches informationnelles tentent de saisir la structure des corrélations non-locales, ainsi que les questions que ces dernières soulèvent concernant la capacité d'un observateur localisé à isoler un système de son environnement. Le second chapitre détaille les effets de l'invariance de Poincaré sur la détection et la quantification de l'intrication. Cette invariance impose que tous les systèmes soient modélisés en dernière instance dans le cadre de la théorie des champs, ce qui implique qu'aucun système à énergie finie ne puisse être localisé, ainsi que la divergence de toute mesure d'intrication pour des observateurs localisés. Nous fournissons une solution à ces deux problèmes en démontrant l'équivalence générique qui existe entre une résolution spatiale finie des appareils de mesure et l'exclusion des degrés de liberté de haute énergie de la définition du système observé. Cette équivalence permet une interprétation épistémique du formalisme quantique standard décrivant les systèmes localisés non-relativistes et leurs corrélations, clarifiant ainsi l'origine des mesures finies d'intrication pour de tels systèmes. Le dernier chapitre explore un cadre théorique récemment introduit qui prédit l'existence de corrélations quantiques sans ordre causal défini. Procédant par analogie avec le cas des corrélations non-locales, nous présentons quelques principes informationnels contraignant la structure de ces corrélations dans le but de mieux en comprendre l'origine physique.
- Published
- 2014
45. Étude et conception d'un système de télésurveillance et de détection de situations critiques par suivi actimétrique des personnes à risques en milieu indoor et outdoor
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Bourennane, Walid, Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Université Toulouse le Mirail - Toulouse II, Éric Campo, and Daniel Estève
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Réseaux de capteurs ,Elderly healthcare ,[INFO.INFO-CY]Computer Science [cs]/Computers and Society [cs.CY] ,Sensor network ,Behaviour learning ,Analyse d'activité ,Monitoring system ,Fusion des données ,Data fusion ,Apprentissage de comportement ,Surveillance des personnes âgées - Abstract
The aging of the population implies an evolution of the healthcare systems, in order to take over dependent people whose proportion is growing. A possible solution is to develop and implement a home care technology. In this context, this PhD work consist to design and test a multisensory monitoring system: deployment of sensors in patient environment, sensory data fusion and automatic diagnostic algorithms, in order allowing patients to live in better safety conditions and helping health professionals to give better care quality. This manuscript presents, in the beginning, the problematic of elderly care and the state of knowledge and practices of activity analysis systems for elderly, through a literature review. Then, it describes the design step of monitoring system according to a functional approach. This approach presents the implemented hardware and software architecture in order to satisfy established specifications. We worked on two projects: 1) Homecare System aims to experiment and validate the good working of a remote monitoring system for elderly (or disabled) suffering from Alzheimer's disease. 2) BéA System (Bracelet Electronique d'Autonomie) is oriented to outdoor monitoring of able-bodied people but frail: Our contribution is to implement a system architecture which integrates a self-adaptive algorithm for detecting and modelling wandering by day-part. For these two projects, we present the results and make a first experience feedback. Finally, we propose a potential economic model that defines the available options that allow, today, the deployment these types of system.; Le vieillissement rapide de la population implique une évolution du système de soins pour prendre en charge les personnes dépendantes dont la proportion ne cesse de croître. Une option possible est de développer et de mettre en œuvre une technologie d'assistance à domicile. Ce travail de thèse consiste à concevoir et à expérimenter des solutions de " surveillance " multicapteurs : déploiement de capteurs dans l'environnement réel du patient, fusion multisensorielle et algorithmes de diagnostics automatiques, afin d'assurer la sécurité des personnes mais également d'aider les professionnels de santé à maintenir la qualité du suivi et des soins. Ce manuscrit présente à travers une étude bibliographique, un état des connaissances et des pratiques sur les systèmes d'analyse des activités des personnes âgées. Ensuite, il détaille l'étape de conception du système de surveillance retenu et selon une approche fonctionnelle présente l'architecture matérielle et logicielle mise en œuvre pour répondre aux spécifications établies. Deux projets sont issus de ce travail : 1) Le projet Homecare qui vise à expérimenter et à qualifier, au niveau opérationnel, un système complet de Télésurveillance pour les personnes âgées atteintes de la maladie d'Alzheimer. 2) Le projet BéA qui est plutôt orienté sur la surveillance " outdoor " pour des personnes valides mais fragiles : Notre contribution a concerné la mise en place d'une architecture système qui intègre un algorithme auto-adaptatif de détection et de modélisation des déambulations par tranche horaire. Enfin, les pistes d'un modèle économique qui définit les options offertes, aujourd'hui, au déploiement de ce type de systèmes sont discutées.
- Published
- 2013
46. Study and design a system for monitoring and detecting critical situations by monitoring actimetric parameters of people at risk indoor and outdoor
- Author
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Bourennane, Walid, Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Université Toulouse le Mirail - Toulouse II, Éric Campo, and Daniel Estève
- Subjects
Réseaux de capteurs ,Elderly healthcare ,[INFO.INFO-CY]Computer Science [cs]/Computers and Society [cs.CY] ,Sensor network ,Behaviour learning ,Analyse d'activité ,Monitoring system ,Fusion des données ,Data fusion ,Apprentissage de comportement ,Surveillance des personnes âgées - Abstract
The aging of the population implies an evolution of the healthcare systems, in order to take over dependent people whose proportion is growing. A possible solution is to develop and implement a home care technology. In this context, this PhD work consist to design and test a multisensory monitoring system: deployment of sensors in patient environment, sensory data fusion and automatic diagnostic algorithms, in order allowing patients to live in better safety conditions and helping health professionals to give better care quality. This manuscript presents, in the beginning, the problematic of elderly care and the state of knowledge and practices of activity analysis systems for elderly, through a literature review. Then, it describes the design step of monitoring system according to a functional approach. This approach presents the implemented hardware and software architecture in order to satisfy established specifications. We worked on two projects: 1) Homecare System aims to experiment and validate the good working of a remote monitoring system for elderly (or disabled) suffering from Alzheimer's disease. 2) BéA System (Bracelet Electronique d'Autonomie) is oriented to outdoor monitoring of able-bodied people but frail: Our contribution is to implement a system architecture which integrates a self-adaptive algorithm for detecting and modelling wandering by day-part. For these two projects, we present the results and make a first experience feedback. Finally, we propose a potential economic model that defines the available options that allow, today, the deployment these types of system.; Le vieillissement rapide de la population implique une évolution du système de soins pour prendre en charge les personnes dépendantes dont la proportion ne cesse de croître. Une option possible est de développer et de mettre en œuvre une technologie d'assistance à domicile. Ce travail de thèse consiste à concevoir et à expérimenter des solutions de " surveillance " multicapteurs : déploiement de capteurs dans l'environnement réel du patient, fusion multisensorielle et algorithmes de diagnostics automatiques, afin d'assurer la sécurité des personnes mais également d'aider les professionnels de santé à maintenir la qualité du suivi et des soins. Ce manuscrit présente à travers une étude bibliographique, un état des connaissances et des pratiques sur les systèmes d'analyse des activités des personnes âgées. Ensuite, il détaille l'étape de conception du système de surveillance retenu et selon une approche fonctionnelle présente l'architecture matérielle et logicielle mise en œuvre pour répondre aux spécifications établies. Deux projets sont issus de ce travail : 1) Le projet Homecare qui vise à expérimenter et à qualifier, au niveau opérationnel, un système complet de Télésurveillance pour les personnes âgées atteintes de la maladie d'Alzheimer. 2) Le projet BéA qui est plutôt orienté sur la surveillance " outdoor " pour des personnes valides mais fragiles : Notre contribution a concerné la mise en place d'une architecture système qui intègre un algorithme auto-adaptatif de détection et de modélisation des déambulations par tranche horaire. Enfin, les pistes d'un modèle économique qui définit les options offertes, aujourd'hui, au déploiement de ce type de systèmes sont discutées.
- Published
- 2013
47. Cooper pair box circuits : two‐qubit gate, single‐shot readout, and current to frequency conversion
- Author
-
Nguyen, Francois, Service de physique de l'état condensé (SPEC - UMR3680), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris VI, and Daniel Estève(daniel.esteve@cea.fr)
- Subjects
bit ,QED ,[PHYS.PHYS]Physics [physics]/Physics [physics] ,transmon ,superconductivity ,CPW ,quantum gate ,Bloch oscillations ,FLICFORQ ,metrologie ,oscillations de Bloch ,[PHYS.COND.CM-S]Physics [physics]/Condensed Matter [cond-mat]/Superconductivity [cond-mat.supr-con] ,quantum ,Computer Science::Emerging Technologies ,metrology ,operation quantique ,superconductivité ,resonateur ,bifurcation ,resonator ,[PHYS.COND]Physics [physics]/Condensed Matter [cond-mat] ,qubit - Abstract
During this thesis, we have used superconducting circuits with Josephson junctions, derived from the Cooper pair box, in order to implement quantum bits (qubits). To implement two-qubit gates, we have developed a new circuit, the quantroswap, which consists in two capacitively coupled Cooper pair box, each of them being manipulated and read separately. We have demonstrated coherent exchange of energy between them, but we have also observed a problem of qubit instability.In order to avoid this spurious effect, we have implemented another circuit based on a charge insensitive split Cooper pair box coupled to a non-linear resonator for readout-out purpose. We have measured large coherence time, and obtained large readout fidelity (90%) using the bifurcation phenomenon. For metrological purpose, microwave reflectometry measurement on a quantronium also allowed us to relate an applied current I to the frequency f=I/2e of induced Bloch oscillations.
- Published
- 2008
48. Manipulation, readout and analysis of the decoherence of a superconducting quantum bit
- Author
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Ithier, Grégoire, Quantronics Group (QUANTRONICS), Service de physique de l'état condensé (SPEC - UMR3680), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut Rayonnement Matière de Saclay (IRAMIS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Université Pierre et Marie Curie - Paris VI, and Daniel Estève(daniel.esteve@cea.fr)
- Subjects
[PHYS.COND.CM-S]Physics [physics]/Condensed Matter [cond-mat]/Superconductivity [cond-mat.supr-con] ,superconducting quantum bit ,Quantum Physics ,QND readout ,decoherence - Abstract
In this thesis work, the quantum behavior of a superconducting circuit implementing a quantum bit orqubit is studied. With the use of resonant microwave pulses the full manipulation of the quantum state of this system is demonstrated: any rotation of the state vector around the Bloch sphere can be achieved and by using particular NMR inspired sequences of microwavepulses, the robustness of an operation against particular types of errors, like slow fluctuations of the transition frequency of the qubit, can be improved.The phenomenon of decoherence which drives the system from a quantum behavior to a classical one, has been characterized in the free evolution regime. By properly tuning the working point in the external parameter space, the qubit can be decoupled to first order from the fluctuations of its environment, thus enhancing coherence. In these optimal conditions, low frequency charge noise probably of microscopic origin appears to be the limiting source of decoherencefor our system. The study of decoherence during driven evolution demonstrated that by suppressing the effect of those fluctuations of the environment slower than that of the driving field, the coherence of the qubit can be improved. Finally a new non-dissipative readout method basedon microwave reflectometry has been set up, which improves the sensitivity and could in principle lead to a non-demolition measurement of the qubit state.
- Published
- 2005
49. Conception, réalisation et caractérisation de capteurs infrarouges à thermopiles : application à la détection de présence passive dans l'habitat
- Author
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Escriba, Christophe, Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Université Paul Sabatier - Toulouse III, Daniel Estève, Eric Campo, Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), and Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP)
- Subjects
Thermopile sensor ,Modélisation analytique ,Capteur thermopile ,Micro-usinage volumique ,Passive infrared detection ,Electronique instrumentale ,Habitat Intelligent ,Bulk micromachining ,Microsystèmes ,Analytical modeling ,Optronique ,Smart home ,Optronic ,Détection infrarouge passive ,[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics ,Instrumental electronics - Abstract
Nowadays, the developments of systems related to the security and the monitoring of people are generally based on the use of mono-points pyrolectric commercial detectors. Those sensors, allowing the detection of an individual moving in the field, exhibit two main limitations: they are not capable to sense an immobile presence and they are unable to provide any extra information, such as the direction of motions and the estimation of distances. Our research work is related to the passive monitoring in the field of smart home applications. It aims at the development of new generations of infrared sensors. After studying the principal materials allowing infrared detection and taking into account the specifications established for our application, we have selected the thermopile thermoelectric technology as the sensor technological platform. According to the general recommendations concerning the "Top-down" design of the microsystems, we have carried out the analytical modeling of the overall infrared detection system before engaging the steps of design and realization. From this conceptual step, several structures (total of 180) in the shape of unit sensors, matrices and vehicles tests were fabricated. Finally, we have developed a specific automated testbench and correlated the experimental characterizations to the analytical model. The results obtained show the validity of the concepts implemented and make it possible to engage as of now the development of static presence detectors.; A ce jour, les développements de systèmes liés à la sécurisation des biens et à la surveillance des personnes s'appuient le plus souvent sur l'usage de détecteurs commerciaux de type pyroélectriques mono-points, indiquant le passage d'une personne dans le champ. Ces détecteurs font apparaître deux limitations : l'impossibilité de détecter lorsque la personne à surveiller est immobile, et la nécessité dans certains cas, d'avoir des informations plus riches que la simple présence (direction des mouvements, estimation de la distance &). Notre travail de recherche se situe dans une perspective liée à la surveillance passive dans le domaine de l'habitat intelligent. Il vise le développement de capteurs infrarouges de nouvelles générations. Au terme d'une investigation sur les principaux matériaux permettant la détection infrarouge et compte tenu de la problématique et des spécifications que nous avons établies, le choix s'est porté sur une technologie thermoélectrique de type thermopile. Selon les recommandations générales concernant la conception "Top-down" des microsystèmes, nous avons fait un travail assez approfondi de modélisation analytique du système global de détection infrarouge avant d'engager les étapes de conception et de réalisation. A partir de cette démarche conceptuelle, plusieurs structures (au total 180) sous la forme de capteurs unitaires, matriciels et de véhicules tests ont été réalisées. Ce travail de recherche se termine par le développement d'un banc de mesures spécifique et la corrélation des caractérisations expérimentales avec le modèle élaboré. Les résultats obtenus montrent la validité des concepts mis en Suvre et permettent d'engager dès à présent le développement de détecteurs de présence statique.
- Published
- 2005
50. Statistic and neural networks for a diagnosis system: Application to automotive failure detection
- Author
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Poulard, Hervé, Laboratoire d'analyse et d'architecture des systèmes (LAAS), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Université Paul Sabatier - Toulouse III, Daniel Estève, Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Université Fédérale Toulouse Midi-Pyrénées
- Subjects
Hypercube ,Analyse en composantes principales ,BCP ,Estimation de densité ,Algorithmes de construction ,Réseaux de neurones ,Mélange de gaussiennes ,[INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation ,Diagnostic par reconnaissance de formes - Abstract
Ce travail a été réalisé dans le cadre d'une convention CIFRE entre le LAAS-CNRS et la société ACTIA qui développe des outils d'aide au diagnostic de pannes automobiles. Le but était l'utilisation des réseaux de neurones artificiels pour la conception d'une nouvelle méthode de diagnostic de pannes automobiles sans modèle, ni information symbolique mais avec seulement des observations du système en bon et en mauvais fonctionnement. C'est donc une approche du diagnostic de système complexe par reconnaissance de formes. Après avoir mis au point le système d'acquisition, nous avons conçu une première maquette qui a démontré la faisabilité d'un tel système et l'intérêt des réseaux de neurones, mais qui a soulevé de nombreux problèmes. L'utilisation particulière des réseaux de neurones dans cette application a nécessité l'usage d'algorithmes de construction. Après une étude théorique des structures de l'hypercube qui n'a pas abouti à un algorithme de construction mais qui a fourni plusieurs résultats, nous avons développé une famille d'algorithmes pour la construction des réseaux de neurones binaires. La base de ces outils est une nouvelle méthode d'apprentissage d'unités à seuil très performante dénommée Barycentric Correction Procedure (BCP). L'aboutissement est un algorithme novateur car très général (entrées quelconques et sorties multiples), rapide et avec un bon pouvoir de généralisation. Nous avons finalement mis au point une nouvelle méthodologie de diagnostic, dans laquelle l'utilisation de méthodes statistiques et d'analyse de données en collaboration avec les réseaux neuronaux paru nécessaire. Cette méthodologie utilise donc des techniques très diverses : analyse en composantes principales, estimation de densité de probabilité, classification automatique, calcul d'enveloppes convexes, génération géométrique de bases d'apprentissage, construction de réseaux de neurones binaires, réseaux de neurones gaussiens et méthodes de diagnostic simples. Cette méthodologie a été appliquée avec succès au problème de la détection de pannes automobiles et a aussi montré des potentialités pour le diagnostic préventif. Elle est de plus assez générique pour avoir de nombreuses applications potentielles.; non disponible
- Published
- 1996
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