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Peri-urban areas of Bujumbura host a significant number of dairy cattle, which consequently ensure a substantial production of milk consumed in the Burundian capital. The presence of these cows in peri-urban areas has led to the emergence of an atypical market for spontaneous forage species. The present study seeks to determine the food and nutritional value of this fodder. A test on its conservation by transformation into silage was also carried out. Botanical field investigations and plant samples collection were carried out under the guidance of fodders suppliers. Based on the bromatological value deficiency thresholds for cattle, the results showed that the content of digestible nitrogenous matter and major elements (Ca, P, K, and Mg) in the forage is within acceptable limits. The final product obtained after fermentation, based on its color, its smell, and its consistency, is indeed silage. The chemical composition of fermented fodder showed that the nutritional quality has remained almost the same. Further research on digestibility of this forage is necessary. A study of the environmental determinants of spontaneous forage distribution at multiple sites and over a wide range of parameters may contribute to a better understanding of the importance of this fodder particularly in times of fodder deficit.

Gallic acid (GA) is a naturally occurring polyphenol compound present in fruits, vegetables, and herbal medicines. According to previous studies, GA has many biological properties, including antioxidant, anticancer, anti-inflammatory, and antimicrobial properties. GA and its derivatives have multiple industrial uses, such as food supplements or additives. Additionally, recent studies have shown that GA and its derivatives not only enhance gut microbiome (GM) activities, but also modulate immune responses. Thus, GA has great potential to facilitate natural defense against microbial infections and modulate the immune response. However, the exact mechanisms of GA acts on the GM and immune system remain unclear. In this review, first the physicochemical properties, bioavailability, absorption, and metabolism of GA are introduced, and then we summarize recent findings concerning its roles in gastrointestinal health. Furthermore, the present review attempts to explain how GA influences the GM and modulates the immune response to maintain intestinal health.

In this study, we investigated the cytoprotective effects of dihydromyricetin (DHM) against deoxynivalenol (DON)-induced toxicity and accompanied metabolic pathway changes in porcine jejunum epithelial cells (IPEC-J2). The cells were incubated in 250 ng/ml DON cotreated with 40 µM DHM, followed by toxicity analysis, oxidative stress reaction analysis, inflammatory response analysis and metabolomic analysis. The results showed that DHM significantly increased the cell viability (P 0.01), the intracellular GSH level (P 0.01) and decreased the intracellular ROS level (P 0.01), the secretion of TNF-α, IL-8 (P 0.01) and the apoptotic cell percentages (P 0.01) in IPEC-J2 cells compared to that in the DON group. Metabolomic analysis revealed that DHM recovered the disorder of metabolic pathways such as glutamate metabolism, arachidonic metabolism and histidine metabolism caused by DON. In summary, DHM alleviated cell injury induced by DON and it is possibly through its antioxidant activity, anti-inflammatory activity or ability to regulate metabolic pathways.