5 results on '"Daniela Melani"'
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2. Positive predictive values and outcomes for uninformative cell-free DNA tests: An Italian multicentric Cytogenetic and cytogenomic Audit of diagnOstic testing (ICARO Study)
- Author
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Francesca Romana Grati, Ilaria Bestetti, Daria De Siero, Francesca Malvestiti, Nicoletta Villa, Elena Sala, Francesca Crosti, Valentina Parisi, Anna Maria Nardone, Gianluca Di Giacomo, Antonella Pettinari, Giada Tortora, Annamaria Montaldi, Annapaola Calò, Donatella Saccilotto, Sara Zanchetti, Paola Celli, Silvana Guerneri, Rosamaria Silipigni, Laura Cardarelli, Elisabetta Lippi, Simona Cavani, Michela Malacarne, Rita Genesio, Nicola Beltrami, Maria Carla Pittalis, Laura Desiderio, Mattia Gentile, Romina Ficarella, Maria Paola Recalcati, Ilaria Catusi, Maria Garzo, Lorena Miele, Cecilia Corti, Sara Ghezzo, Veronica Bertini, Francesca Cambi, Angelo Valetto, Barbara Facchinetti, Laura Bernardini, Anna Capalbo, Federica Balducci, Elisabetta Pelo, Barbara Minuti, Chiara Pescucci, Costanza Giuliani, Alessandra Renieri, Ilaria Longo, Rossella Tita, Giuseppe Castello, Rosario Casalone, Rossana Righi, Barbara Raso, Alessandro Civolani, Maria Cristina Muzi, Manuela di Natale, Luigia Varriale, Daniela Gasperini, Maria Cristina Nuzzi, Angelo Cellamare, Paola Casieri, Rosa Busuito, Caterina Ceccarini, Carla Cesarano, Orsola Privitera, Daniela Melani, Cristina Menozzi, Cristina Falcinelli, Olga Calabrese, Paola Battaglia, Antonella Tanzariello, Tamara Stampalija, Carmela Ardisia, Paolo Gasparini, Peter Benn, Antonio Novelli, Grati, Francesca Romana, Bestetti, Ilaria, De Siero, Daria, Malvestiti, Francesca, Villa, Nicoletta, Sala, Elena, Crosti, Francesca, Parisi, Valentina, Nardone, Anna Maria, Di Giacomo, Gianluca, Pettinari, Antonella, Tortora, Giada, Montaldi, Annamaria, Calò, Annapaola, Saccilotto, Donatella, Zanchetti, Sara, Celli, Paola, Guerneri, Silvana, Silipigni, Rosamaria, Cardarelli, Laura, Lippi, Elisabetta, Cavani, Simona, Malacarne, Michela, Genesio, Rita, Beltrami, Nicola, Pittalis, Maria Carla, Desiderio, Laura, Gentile, Mattia, Ficarella, Romina, Recalcati, Maria Paola, Catusi, Ilaria, Garzo, Maria, Miele, Lorena, Corti, Cecilia, Ghezzo, Sara, Bertini, Veronica, Cambi, Francesca, Valetto, Angelo, Facchinetti, Barbara, Bernardini, Laura, Capalbo, Anna, Balducci, Federica, Pelo, Elisabetta, Minuti, Barbara, Pescucci, Chiara, Giuliani, Costanza, Renieri, Alessandra, Longo, Ilaria, Tita, Rossella, Castello, Giuseppe, Casalone, Rosario, Righi, Rossana, Raso, Barbara, Civolani, Alessandro, Muzi, Maria Cristina, di Natale, Manuela, Varriale, Luigia, Gasperini, Daniela, Nuzzi, Maria Cristina, Cellamare, Angelo, Casieri, Paola, Busuito, Rosa, Ceccarini, Caterina, Cesarano, Carla, Privitera, Orsola, Melani, Daniela, Menozzi, Cristina, Falcinelli, Cristina, Calabrese, Olga, Battaglia, Paola, Tanzariello, Antonella, Stampalija, Tamara, Ardisia, Carmela, Gasparini, Paolo, Benn, Peter, and Novelli, Antonio
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cfDNAtesting ,Obstetrics and Gynecology ,Genetics (clinical) - Abstract
Objectives: To establish the positive predictive values (PPV) of cfDNA testing based on data from a nationwide survey of independent clinical cytogenetics laboratories. Methods: Prenatal diagnostic test results obtained by Italian laboratories between 2013 and March 2020 were compiled for women with positive non-invasive prenatal tests (NIPT), without an NIPT result, and cases where there was sex discordancy between the NIPT and ultrasound. PPV and other summary data were reviewed. Results: Diagnostic test results were collected for 1327 women with a positive NIPT. The highest PPVs were for Trisomy (T) 21 (624/671, 93%) and XYY (26/27, 96.3%), while rare autosomal trisomies (9/47, 19.1%) and recurrent microdeletions (8/55, 14.5%) had the lowest PPVs. PPVs for T21, T18, and T13 were significantly higher when diagnostic confirmation was carried out on chorionic villi (97.5%) compared to amniotic fluid (89.5%) (p < 0.001). In 19/139 (13.9%), of no result cases, a cytogenetic abnormality was detected. Follow-up genetic testing provided explanations for 3/6 cases with a fetal sex discordancy between NIPT and ultrasound. Conclusions: NIPT PPVs differ across the conditions screened and the tissues studied in diagnostic testing. This variability, issues associated with fetal sex discordancy, and no results, illustrate the importance of pre- and post-test counselling.
- Published
- 2022
3. Do trade openness, environmental degradation and oil prices affect green energy consumption?
- Author
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Lingli Qing, Yangyang Yao, Crenguta-Ileana Sinisi, Asma Salman, Mohammad Jaradat, Adina Eleonora Spinu, Daniela Melania Mihai, and Malik Shahzad Shabbir
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K32 ,O13 ,Energy industries. Energy policy. Fuel trade ,HD9502-9502.5 - Abstract
This study aims to examine the congruence of trade openness with regards to encouraging pervasive usage of green energy sources and the nexus among environmental degradation, economic development, oil prices, and green energy consumption (GEC). The study utilizes advanced panel data techniques, including the Westerlund cointegration test, Augmented Mean Group (AMG) estimator, Pooled Mean Group (PMG) estimator, and the Dumitrescu and Hurlin (DH) causality test, to examine the aforementioned relationships. The findings of the AMG and PMG estimators indicate that environmental degradation has a negative impact on GEC, whereas oil prices and economic development have a positive effect on GEC.
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- 2024
- Full Text
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4. IMPLICATIONS OF THE HEALTH CRISIS GENERATED BY THE COVID-19 PANDEMIC ON THE ROMANIAN LABOUR MARKET
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Madalina BRUTU and Daniela Melania MIHAI
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labour market ,employees ,covid-19 pandemic. ,Economic theory. Demography ,HB1-3840 - Abstract
The International Labour Organization warns that the Pandemic will have devastating effects on the labour market, worldwide. It specified that an impressive number of employees have already been affected by the social distancing measures and that this crisis will be the worst for the labour market since World War II. The impact of the pandemic has been and is still strongly felt on the Romanian labour market as well. Most companies in the economy sent their employees in technical unemployment in the spring of 2020, and most employments are cancelled, postponed or frozen. The European Commission forecast that the Romanian economy will contract by 5.2% in 2020 and the deficit will grow by 10.3% of GDP. The hope for November 2020 comes from the pharmaceutical companies Pfizer and BioNTech who announced an efficacy of 90% of the Covid-19 vaccine and from which the European Commission has already contracted 300 million doses of vaccine, at a lower price than that the USA will pay.
- Published
- 2020
5. TOURISM MANAGEMENT AND PLANNING OF CLIMATIC AND SPA RESORTS IN ROMANIA
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Smaranda TOMA and Daniela Melania MIHAI
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Tourism management ,Tourism planning ,Climatic resort ,Spa ,Economic theory. Demography ,HB1-3840 - Abstract
This paper refers to the management, planning, certification and authorization of climatic and spa resorts, as well as to the organizing activity of using the natural therapeutic factors in Romania. The certified climatic and spa resorts are delimited by urbanism and territory planning plans. The predominant type of natural therapeutic factors determines the specificity of a resort and its therapeutic profile. Romania has 108 certified tourist resorts. The statute of climatic and spa resort is granted by Government decisions. The functioning authorization for the natural therapeutic factors, medical-spa and recovery units in climatic and spa resorts, is issued by the National Institute of Recovery, Physical Medicine and Balneoclimatology. The coordination and control of health care activity in spa and climatic resorts and the proper organization and functioning of these resorts are carried out by the Ministry of Health. The current legislation provides a series of technical rules on systemizing and organizing climatic and spa resorts. Since the legislative terms are met, a proper tourism management and planning, a better involvement of local and national authorities, a better and diversified offer, a new strategy to develop medical tourism, and a better promotion of the Romanian balneological tourism are the key elements to develop medical tourism in Romania, to the benefit of all stakeholders.
- Published
- 2018
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