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163 results on '"Danzon, Arlette"'

1. Quantifying the mediating effects of smoking and occupational exposures in the relation between education and lung cancer: the ICARE study

Author: Menvielle, Gwenn, Franck, Jeanna-eve, Radoï, Loredana, Sanchez, Marie, Févotte, Joëlle, Guizard, Anne-Valérie, Stücker, Isabelle, Luce, Danièle, Woronoff, Anne-Sophie, Guizard, Anne-Valérie, Schmaus, Annie, Buemi, Antoine, Danzon, Arlette, Lapotre-Ledoux, Benedicte, Tretarre, Brigitte, Pilorget, Corinne, Luce, Danièle, Cyr, Diane, Marrer, Émilie, Lamkarkach, Farida, Guida, Florence, Molinie, Florence, Menvielle, Gwenn, Stücker, Isabelle, Févotte, Joëlle, Radoï, Loredana, Colonna, Marc, Sanchez, Marie, Carton, Matthieu, Velten, Michel, Raverdy, Nicole, Gaye, Oumar, Bercelli, Paolo, Delafosse, Patricia, Bara, Simona, Cénée, Sylvie, and ICARE study group
Published: 2016
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2. Cancer incidence estimation at a district level without a national registry: A validation study for 24 cancer sites using French health insurance and registry data

Author: Uhry, Zoé, Remontet, Laurent, Colonna, Marc, Belot, Aurélien, Grosclaude, Pascale, Mitton, Nicolas, Delacour-Billon, Solenne, Gentil, Julie, Boussac-Zarebska, Marjorie, Bossard, Nadine, Danzon, Arlette, Altana, Michelle, Frete, François, Weill, Alain, and Rogel, Agnès
Published: 2013
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3. Trends in incidence of digestive cancers in France

Author: Lepage, Côme, Remontet, Laurent, Launoy, Guy, Trétarre, Brigitte, Grosclaude, Pascale, Colonna, Marc, Velten, Michel, Buemi, Antoine, Danzon, Arlette, Molinie, Florence, Maarouf, Nabil, Bossard, Nadine, Bouvier, Anne-Marie, and Faivre, Jean
Published: 2008

4. Trends in invasive breast cancer incidence among French women not exposed to organized mammography screening: An age-period-cohort analysis

Author: Viel, Jean-François, Rymzhanova, Raouchan, Fournier, Evelyne, and Danzon, Arlette
Published: 2011
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5. Reliability of recording uterine cancer in death certification in France and age-specific proportions of deaths from cervix and corpus uteri

Author: Rogel, Agnès, Belot, Aurélien, Suzan, Florence, Bossard, Nadine, Boussac, Marjorie, Arveux, Patrick, Buémi, Antoine, Colonna, Marc, Danzon, Arlette, Ganry, Olivier, Guizard, Anne-Valérie, Grosclaude, Pascale, Velten, Michel, Jougla, Eric, Iwaz, Jean, Estève, Jacques, Chérié-Challine, Laurence, and Remontet, Laurent
Published: 2011
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6. Welding, a risk factor of lung cancer: the ICARE study

Author: Matrat, Mireille, Guida, Florence, Mattei, Francesca, Cénée, Sylvie, Cyr, Diane, Févotte, Joëlle, Sanchez, Marie, Menvielle, Gwenn, Radoï, Loredana, Schmaus, Annie, Woronoff, Anne-Sophie, Luce, Danièle, Stücker, Isabelle, Guizard, Anne-Valérie, Danzon, Arlette, Michel, Velten, Buemi, Antoine, Marrer, Émilie, Tretarre, Brigitte, Colonna, Marc, Delafosse, Patricia, Bercelli, Paolo, Molinie, Florence, Bara, Simona, Lapotre-Ledoux, Benedicte, Raverdy, Nicole, Gaye, Oumar, Lamkarkach, Farida, and Pilorget, Corinne
Published: 2016
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7. The joint effect of asbestos exposure, tobacco smoking and alcohol drinking on laryngeal cancer risk: evidence from the French population-based case–control study, ICARE

Author: Menvielle, Gwenn, Fayossé, Aurore, Radoï, Loredana, Guida, Florence, Sanchez, Marie, Carton, Matthieu, Cyr, Diane, Schmaus, Annie, Cénée, Sylvie, Fevotte, Joëlle, Delafosse, Patricia, Stücker, Isabelle, Luce, Danièle, Guizard, Anne-Valérie, Danzon, Arlette, Woronoff, Anne-Sophie, Michel, Velten, Buemi, Antoine, Marrer, Émilie, Tretarre, Brigitte, Colonna, Marc, Bercelli, Paolo, Molinie, Florence, Bara, Simona, Lapotre-Ledoux, Benedicte, Raverdy, Nicole, Gaye, Oumar, and Lamkarkach, Farida
Published: 2016
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8. Anthropometric Risk Factors for Differentiated Thyroid Cancer in Young Men and Women From Eastern France: A Case-Control Study

Author: Xhaard, Constance, de Vathaire, Florent, Cléro, Enora, Maillard, Stéphane, Ren, Yan, Borson-Chazot, Françoise, Sassolas, Geneviève, Schvartz, Claire, Colonna, Marc, Lacour, Brigitte, Danzon, Arlette, Velten, Michel, Marrer, Emilie, Bailly, Laurent, Barjoan, Eugènia Mariné, Schlumberger, Martin, Orgiazzi, Jacques, Adjadj, Elisabeth, and Rubino, Carole
Published: 2015
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9. Menstrual and Reproductive Factors in the Risk of Differentiated Thyroid Carcinoma in Young Women in France: A Population-Based Case-Control Study

Author: Xhaard, Constance, Rubino, Carole, Cléro, Enora, Maillard, Stéphane, Ren, Yan, Borson-Chazot, Françoise, Sassolas, Geneviève, Schvartz, Claire, Colonna, Marc, Lacour, Brigitte, Danzon, Arlette, Velten, Michel, Buemi, Antoine, Bailly, Laurent, Mariné Barjoan, Eugènia, Schlumberger, Martin, Orgiazzi, Jacques, Adjadj, Elisabeth, and de Vathaire, Florent
Published: 2014
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10. Are the effects of air pollution on birth weight modified by infant sex and neighborhood socioeconomic deprivation? A multilevel analysis in Paris (France)

Author: Deguen, Séverine, primary, Kihal-Talantikite, Wahida, additional, Gilles, Morgane, additional, Danzon, Arlette, additional, Carayol, Marion, additional, and Zmirou-Navier, Denis, additional
Published: 2021
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11. Long-term quality of life after breast cancer: a French registry-based controlled study

Author: Klein, Delphine, Mercier, Mariette, Abeilard, Edwige, Puyraveau, Marc, Danzon, Arlette, Dalstein, Véronique, Pozet, Astrid, Guizard, Anne-Valérie, Henry-Amar, Michel, and Velten, Michel
Published: 2011
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12. Rurality and survival differences in lung cancer: A large population-based multivariate analysis

Author: Pozet, Astrid, Westeel, Virginie, Berion, Pascal, Danzon, Arlette, Debieuvre, Didier, Breton, Jean-Luc, Monnier, Alain, Lahourcade, Jean, Dalphin, Jean-Charles, and Mercier, Mariette
Published: 2008
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13. Cancer adolescent pathway in France between 1988 and 1997

Author: Desandes, Emmanuel, Lacour, Brigitte, Sommelet, Danièle, White-Koning, Mélanie, Velten, Michel, Tretarre, Brigitte, Marr, Angelina, Maarouf, Nabil, Guizard, Anne-Valérie, Delafosse, Patricia, Danzon, Arlette, Cotte, Christine, and Brugieres, Laurence
Published: 2007
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14. Adverse Birth Outcomes as Indicators of Poor Fetal Growth Conditions in a French Newborn Population—A Stratified Analysis by Neighborhood Deprivation Level

Author: Kihal-Talantikite, Wahida, primary, Le Nouveau, Pauline, additional, Legendre, Pierre, additional, Zmirou Navier, Denis, additional, Danzon, Arlette, additional, Carayol, Marion, additional, and Deguen, Séverine, additional
Published: 2019
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15. The Role of Circumstances of Diagnosis and Access to Dermatological Care in Early Diagnosis of Cutaneous Melanoma: A Population-Based Study in France

Author: Durbec, Frédérique, Vitry, Fabien, Granel-Brocard, Florence, Lipsker, Dan, Aubin, François, Hédelin, Guy, Dalac, Sophie, Truchetet, François, Michel, Catherine, Batard, Marie-Laure, Domissy-Baury, Beatrice, Halna, Jean-Michel, Schmutz, Jean Luc, Delvincourt, Christian, Reuter, Georges, Dalle, Stéphane, Bernard, Philippe, Danzon, Arlette, and Grange, Florent
Published: 2010

16. Variations in Management of Stage I to Stage III Cutaneous Melanoma: A Population-Based Study of Clinical Practices in France

Author: Grange, Florent, Vitry, Fabien, Granel-Brocard, Florence, Lipsker, Dan, Aubin, Francois, Hédelin, Guy, Dalac, Sophie, Truchetet, François, Michel, Catherine, Batard, Marie-Laure, Baury, Béatrice, Halna, Jean-Michel, Schmutz, Jean Luc, Delvincourt, Christian, Reuter, Georges, Dalle, Stéphane, Bernard, Phillipe, and Danzon, Arlette
Published: 2008

17. Variations in management of stage to stage III cutaneous melanoma: a population-based study of clinical practices in France

Author: Grange, Florent, Vitry, Fabien, Granel-Brocard, Florence, Lipsker, Dan, Aubin, Francois, Hedelin, Guy, Dalac, Sophie, Truchetet, Francois, Michel, Catherine, Batard, Marie-Laure, Baury, Beatrice, Halna, Jean-Michel, Schmutz, Jean Luc, Delvincourt, Christian, Reuter, Georges, Dalle, Stephane, Bernard, Phillipe, and Danzon, Arlette
Subjects: Melanoma -- Diagnosis, Melanoma -- Care and treatment, Skin cancer -- Diagnosis, Skin cancer -- Care and treatment, Health
Published: 2008

18. Regional variations in management of rectal cancer in France

Author: Phelip, Jean-Marc, Launoy, Guy, Colonna, Marc, Grosclaude, Pascale, Velten, Michel, Danzon, Arlette, Raverdy, Nicole, Tretarre, Brigitte, Bouvier, Anne-Marie, and Faivre, Jean
Published: 2004
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19. Breast carcinoma survival in Europe and the United States: a population-based study

Author: Sant, Milena, Allemani, Claudia, Berrino, Franco, Coleman, Michel P., Aareleid, Tiiu, Chaplain, Gilles, Coebergh, Jan Willem, Colonna, Marc, Crosignani, Paolo, Danzon, Arlette, Federico, Massimo, Gafa, Lorenzo, Grosclaude, Pascale, Hedelin, Guy, Mace-Lesech, Josette, Garcia, Carmen Martinez, Moller, Henrik, Paci, Eugenio, Raverdy, Nicole, Tretarre, Brigitte, and Williams, Evelyn M. I.
Subjects: Cancer survivors -- Research, Cancer survivors -- Statistics, Breast cancer -- Care and treatment, Breast cancer -- Statistics, Health
Published: 2004

20. Age-period-cohort modelling of non-Hodgkin's lymphoma incidence in a French region: a period effect compatible with an environmental exposure

Author: Viel Jean-François, Fournier Evelyne, and Danzon Arlette
Subjects: Industrial medicine. Industrial hygiene, RC963-969, Public aspects of medicine, RA1-1270
Abstract: Abstract Background The incidence of non-Hodgkin's lymphoma (NHL) has risen steadily during the last few decades in all geographic regions covered by cancer registration for reasons that remain unknown. The aims of this study were to assess the relative contributions of age, period and cohort effects to NHL incidence patterns and therefore to provide clues to explain the increasing incidence. Methods Population and NHL incidence data were provided for the Doubs region (France) during the 1980-2005 period. NHL counts and person-years were tabulated into one-year classes by age (from 20 to 89) and calendar time period. Age-period-cohort models with parametric smooth functions (natural splines) were fitted to the data by assuming a Poisson distribution for the observed number of NHL cases. Results The age-standardised incidence rate increased from 4.7 in 1980 to 11.9 per 100,000 person-years at risk in 1992 (corresponding to a 2.5-fold increase) and stabilised afterwards (11.1 per 100,000 in 2005). Age effects showed a steadily increasing slope up to the age of 80 and levelled off for older ages. Large period curvature effects, both adjusted for cohort effects and non-adjusted (p < 10-4 and p < 10-5, respectively), showed departure from linear periodic trends; period effects jumped markedly in 1983 and stabilised in 1992 after a 2.4-fold increase (compared to the 1980 period). In both the age-period-cohort model and the age-cohort model, cohort curvature effects were not statistically significant (p = 0.46 and p = 0.08, respectively). Conclusions The increased NHL incidence in the Doubs region is mostly dependent on factors associated with age and calendar periods instead of cohorts. We found evidence for a levelling off in both incidence rates and period effects beginning in 1992. It is unlikely that the changes in classification (which occurred after 1995) and the improvements of diagnostic accuracy could largely account for the 1983-1992 period-effect increase, giving way to an increased exposure to widely distributed risk factors including persistent organic pollutants and pesticides. Continued NHL incidence and careful analysis of period effects are of utmost importance to elucidate the enigmatic epidemiology of NHL.
Published: 2010
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21. Dioxin emissions from a municipal solid waste incinerator and risk of invasive breast cancer: a population-based case-control study with GIS-derived exposure

Author: Challier Bruno, Grandjean Sébastien, Hägi Mathieu, Clément Marie-Caroline, Viel Jean-François, and Danzon Arlette
Subjects: Computer applications to medicine. Medical informatics, R858-859.7
Abstract: Abstract Background To date, few epidemiologic studies have examined the relationship between environmental PCDD/F exposure and breast cancer in human populations. Dioxin emissions from municipal solid waste incinerators (MSWIs) are one of the major sources of environmental dioxins and are therefore an exposure source of public concern. The purpose of this study was to examine the association between dioxins emitted from a polluting MSWI and invasive breast cancer risk among women residing in the area under direct influence of the facility. Methods We compared 434 incident cases of invasive breast cancer diagnosed between 1996 and 2002, and 2170 controls randomly selected from the 1999 population census. A validated dispersion model was used as a proxy for dioxin exposure, yielding four exposure categories. The latter were linked to individual places of residence, using Geographic Information System technology. Results The age distribution at diagnosis for all cases combined showed a bimodal pattern with incidence peaks near 50 and 70 years old. This prompted us to run models separately for women aged 20–59 years, and women aged 60 years or older. Among women younger than 60 years old, no increased or decreased risk was found for any dioxin exposure category. Conversely, women over 60 years old living in the highest exposed zone were 0.31 time less likely (95% confidence interval, 0.08–0.89) to develop invasive breast cancer. Conclusion Before speculating that this decreased risk reflects a dioxin anti-estrogenic activity with greater effect on late-onset acquired breast cancer, some residual confounding must be envisaged.
Published: 2008
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22. Using a Clustering Approach to Investigate Socio-Environmental Inequality in Preterm Birth—A Study Conducted at Fine Spatial Scale in Paris (France)

Author: Deguen, Severine, primary, Ahlers, Nina, additional, Gilles, Morgane, additional, Danzon, Arlette, additional, Carayol, Marion, additional, Zmirou-Navier, Denis, additional, and Kihal-Talantikite, Wahida, additional
Published: 2018
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23. Incidence and survival of gastric non-Hodgkin's lymphoma: A population-based study from the Association of the French Cancer Registries (FRANCIM)

Author: Danzon, Arlette, Belot, Aurélien, Maynadié, Marc, Remontet, Laurent, Dupont, Anne Claire Gossart, Carbonnel, Franck, Renseigné, Non, FRANCIM, Réseau des registres français du cancer, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (UR 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Service de Biostatistique, Hospices Civils de Lyon (HCL), Biostatistiques santé, Département biostatistiques et modélisation pour la santé et l'environnement [LBBE], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Département des maladies chroniques et traumatismes, Institut de Veille Sanitaire (INVS), Registre des hémopathies malignes de Côte d'Or, Service de biostatistique, Agents pathogènes et inflammation - UFC (EA 4266) (API), Université de Franche-Comté (UFC), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Hospices Civils de Lyon ( HCL ), Laboratoire de Biométrie et Biologie Evolutive ( LBBE ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique ( Inria ) -Centre National de la Recherche Scientifique ( CNRS ), Agents pathogènes et inflammation - UFC (EA 4266) ( API ), and Université de Franche-Comté ( UFC )
Subjects: Male, Multivariate analysis, MESH: Registries, MESH : Age Distribution, MESH : Aged, 0302 clinical medicine, MESH: Lymphoma, Non-Hodgkin, Risk Factors, MESH: Risk Factors, Epidemiology, MESH : Stomach Neoplasms, MESH : Neoplasm Staging, MESH : Female, Registries, MESH: Incidence, 030212 general & internal medicine, Age of Onset, MESH : Sex Distribution, MESH: Aged, MESH : Prognosis, MESH: Middle Aged, Relative survival, Incidence, Lymphoma, Non-Hodgkin, Incidence (epidemiology), MESH: Sex Distribution, Not Otherwise Specified, MESH: Stomach Neoplasms, MESH: Neoplasm Staging, Hematology, General Medicine, Middle Aged, MESH : Adult, Prognosis, MESH : Risk Factors, MESH : Incidence, MESH : Age of Onset, 3. Good health, Oncology, MESH: Young Adult, MESH: Survival Analysis, 030220 oncology & carcinogenesis, Female, [ SDV.MHEP.HEG ] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, France, Adult, medicine.medical_specialty, Adolescent, MESH : Male, MESH: Age of Onset, MESH : Young Adult, MESH: Multivariate Analysis, MESH: Prognosis, Young Adult, 03 medical and health sciences, Age Distribution, Stomach Neoplasms, MESH : Adolescent, Internal medicine, medicine, Humans, MESH : Middle Aged, MESH : Lymphoma, Non-Hodgkin, Radiology, Nuclear Medicine and imaging, Sex Distribution, MESH : France, MESH: Age Distribution, Survival analysis, Aged, Neoplasm Staging, MESH: Adolescent, MESH: Humans, business.industry, MESH : Humans, MESH : Multivariate Analysis, Cancer, MESH: Adult, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, Survival Analysis, MESH: Male, MESH: France, Multivariate Analysis, Immunology, MESH : Survival Analysis, Age of onset, business, MESH: Female, MESH : Registries
Abstract: International audience; BACKGROUND: Most epidemiological studies on gastric lymphomas (GL) were carried out before changes in therapy were introduced. The aim of the study was to measure the incidence of GL and to estimate survival. MATERIAL AND METHODS: Data were provided by the Association of the French Cancer Registries database. Age-standardized incidence rates were calculated for 786 incident cases diagnosed between 1978 and 2002. Crude and relative survival were calculated for 361 cases diagnosed between 1989 and 1997. Effects specific to sex, age at diagnosis, year of diagnosis, and grade of malignancy were estimated in multivariate analysis. RESULTS: Incidence was stable during the study period. However, high-grade GL frequency increased whereas low-grade and not otherwise specified (NOS) GL frequencies were respectively stable and decreased. At 5 years, relative survival was 63% in men and 60% in women. Patients aged 75 or older had a five-year relative survival of 33%. Age at diagnosis was the only significant prognostic factor in multivariate analysis. Time trend improvement in prognosis was observed. DISCUSSION: Results in elderly patients show that therapeutic regimens should be specifically designed and assessed for them. The prognosis improvement trend is probably related to the implementation of changes in management of patients and has to be confirmed by more recent data.
Published: 2009

24. Pregnancy Air Exposure: An R Package for Estimation of Exposure to Air Pollution during Critical Windows of Pregnancy

Author: Deguen, Séverine, primary, Nicollet, Laure, additional, Gilles, Morgane, additional, Danzon, Arlette, additional, Blanchard, Olivier, additional, Nir, Géraldine Le, additional, Zmirou-Navier, Denis, additional, and Kihal-Talantikite, Wahida, additional
Published: 2017
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25. Recreational Physical Activity and Differentiated Thyroid Cancer Risk: A Pooled Analysis of Two Case-Control Studies

Author: Xhaard, Constance, primary, Lence-Anta, Juan J., additional, Ren, Yan, additional, Borson-Chazot, Françoise, additional, Sassolas, Geneviève, additional, Schvartz, Claire, additional, Colonna, Marc, additional, Lacour, Brigitte, additional, Danzon, Arlette, additional, Velten, Michel, additional, Clero, Enora, additional, Maillard, Stéphane, additional, Marrer, Emilie, additional, Bailly, Laurent, additional, Mariné Barjoan, Eugènia, additional, Schlumberger, Martin, additional, Orgiazzi, Jacques, additional, Adjadj, Elisabeth, additional, Pereda, Celia M., additional, Turcios, Silvia, additional, Velasco, Milagros, additional, Chappe, Mae, additional, Infante, Idalmis, additional, Bustillo, Marlene, additional, García, Anabel, additional, Salazar, Sirced, additional, Rodriguez, Regla, additional, Benadjaoud, Mohamed Amine, additional, Ortiz, Rosa M., additional, Rubino, Carole, additional, and de Vathaire, Florent, additional
Published: 2016
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26. Health-related quality of life among long-term survivors of colorectal cancer: a population-based study

Author: Caravati-Jouvenceaux , Agnès, Launoy , Guy, Klein , Delphine, Henry-Amar , Michel, Abeilard , Edwige, Danzon , Arlette, Pozet , Astrid, Velten , Michel, Mercier , Mariette, Bas-Rhin Cancer Registry, EA 3430, Department of Epidemiology and Public Health, Faculty of Medicine, Calvados Cancer Registry, Centre Régional de Lutte contre le Cancer François Baclesse ( CRLC François Baclesse ), Doubs Cancer Registry, University Hospital Jean Minjoz, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Cancer Clinical Research Unit, Department of Epidemiology and Biostatistics, and Paul Strauss Comprehensive Cancer Center
Subjects: humanities, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Abstract: International audience; BACKGROUND: The number of long-term colorectal cancer survivors is increasing. Cancer and its treatment can cause physical and psychological complications, but little is known about how it impacts quality of life (QOL) over the long term-5, 10, and 15 years after diagnosis. METHODS: Cancer survivors were randomly selected from three tumor registries in France, diagnosed in 1990 (±1 year), 1995 (±1 year), and 2000 (±1 year). Controls were randomly selected from electoral rolls, stratifying on gender, age group, and residence area. Participants completed two QOL questionnaires, a fatigue questionnaire, an anxiety questionnaire, and a life conditions questionnaire. An analysis of variance was used to compare QOL scores of cancer survivors by period of diagnosis (5, 10, and 15 years) with those of controls, adjusted for sociodemographic data and comorbidities. RESULTS: We included 344 colon cancer and 198 rectal cancer survivors and 1,181 controls. In a global analysis, survivors reported a statistically and clinically significant lower score in social functioning 5 years after diagnosis and higher scores in diarrhea symptoms 5 and 10 years after diagnosis. In subgroup analyses, rectal cancer affected QOL in the physical dimensions at 5 years and in the fatigue dimensions at 5 and 10 years. CONCLUSION: Survivors of colorectal cancer may experience the effects of cancer and its treatment up to 10 years after diagnosis, particularly for rectal cancer. Clinicians, psychologists, and social workers must pay special attention to rectal cancer survivors to improve overall management.
Published: 2011

27. Le cancer de la prostate en France en 2001: état des pratiques et facteurs associés à la réalisation d’une prostatectomie totale

Author: Jegu, Jérémie, Tretarre, Brigitte, Velten, Michel, Guizard, Anne-Valérie, Danzon, Arlette, Buemi, Antoine, Colonna, Marc, Kadi-Hanifi, A.-M., Ganry, Olivier, Molinie, Florence, Bara, Simona, Rebillard, Xavier, Grosclaude, Pascale, Vesin, Aurélien, Registre général des cancers du Tarn, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Epidémiologie et Analyses en Santé Publique : risques, maladies chroniques et handicap (LEASP), Institut National de la Santé et de la Recherche Médicale (INSERM), FRANCIM, Réseau des registres français du cancer, Service d'urologie, and Clinique Beausoleil
Subjects: [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Abstract: International audience; INTRODUCTION: Prostate cancer was the most common cancer in men in France in 2005, and the second cause of male death from cancer. In this study, we analyzed clinical characteristics of patients with prostate cancer diagnosed in France in 2001 with a focus on therapeutic management of localized prostate cancers. PATIENTS AND METHODS: A total of 2181 cases of prostate cancer diagnosed in 2001 from 11 French counties covered by a cancer registry were analyzed. A descriptive study of the clinical characteristics of patients was performed. Parameters studied included age, county, TNM stage, PSA value, Gleason score, D'Amico prognostic group, Charlson's comorbidity index and initial treatment modalities. For localized cancers, multivariate logistic regression analysis identified factors associated with radical prostatectomy. RESULTS: The proportion of localized prostate cancer (T1 or T2) was 86.6 %. The use of invasive curative treatment (radical prostatectomy and radiotherapy) was 58.4 % for localized cancers. Significant differences in therapeutic management were found between counties. Radical prostatectomy was associated with age at diagnosis, D'Amico prognostic group and the presence of comorbidities. CONCLUSIONS: Most of prostate cancers diagnosed in France in 2001 were clinically localized and were treated by invasive therapy. The consequences of these practices remain to be determined given the limited evolution of many prostate cancers and the frequency of adverse events related to invasive treatments.
Published: 2010

28. Evolution of pleural cancers and malignant pleural mesothelioma incidence in France between 1980 and 2005

Author: Le Stang, Nolwenn, Belot, Aurélien, Gilg Soit Ilg, Anabelle, Rolland, P., Astoul, Philippe, Bara, Simona, Brochard, Patrick, Danzon, Arlette, Delafosse, Patricia, Grosclaude, Pascale, Guizard, Anne-Valérie, Imbernon, Ellen, Lapôtre-Ledoux, Bénédicte, Ligier, Karine, Molinié, Florence, Pairon, Jean-Claude, Sauleau, Erik-André, Trétarre, Brigitte, Velten, Michel, Bossard, Nadine, Goldberg, Marcel, Launoy, Guy, Galateau-Sallé, Françoise, Launoy, Guy, Registre multicentrique à vocation nationale des mésothéliomes pleuraux, Registre Multicentrique à Vocation Nationale des Mésothéliomes Pleuraux (MESONAT), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Cancers et Populations : Facteurs de Risque, Depistage, Pratiques Diagnostiques et Therapeutiques, Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Biostatistique, Hospices Civils de Lyon (HCL), Biostatistiques santé, Département biostatistiques et modélisation pour la santé et l'environnement [LBBE], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Département des maladies chroniques et traumatismes, Institut de Veille Sanitaire (INVS), Département santé travail (DST-InVS), Division d'oncologie thoracique, Département des maladies pulmonaires, Université de la Méditerranée - Aix-Marseille 2-Assistance Publique - Hôpitaux de Marseille (APHM)-Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), FRANCIM, Réseau des registres français du cancer, Laboratoire Santé Travail Environnement, Université Bordeaux Segalen - Bordeaux 2-IFR99, Service de Médecine du Travail et de Pathologies Professionnelles, CHU Bordeaux [Bordeaux], Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service de pneumologie et pathologie professionnelle, CHI Créteil, Center for Neurologic Diseases, and Brigham and Women's Hospital [Boston]
Subjects: Male, Mesothelioma, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Incidence, Pleural Neoplasms, Humans, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Female, France, Registries, respiratory system, neoplasms, respiratory tract diseases
Abstract: International audience; The evolution of pleural cancers and malignant pleural mesothelioma incidence in France between 1980 and 2005 was analysed using data derived from the French network of cancer registries (FRANCIM) and the French National Mesothelioma Surveillance Program (PNSM). Mesothelioma proportions in pleural cancers were calculated by diagnosis year in the 1980-2000 period. Our results suggest that the incidences of pleural cancer and mesothelioma levelled off in French men since 2000 and continued to increase in French women. A decrease of the annual pleural cancer incidence average in men was noticed (-3.4% of annual rate of change) between 2000 and 2005. The proportion of pleural cancers that were mesothelioma was unchanged between 1980 and 2003 with an average of 86%. The age standardised incidence rate of pleural mesothelioma remained relatively stable between 1998 and 2005 with a slight falling trend. For women, the age standardised incidence rate of pleural cancers and mesothelioma increased during the period 1998-2005. Additionally, the proportion of pleural cancers that were mesothelioma increased during the same period of time. Finally, the increased trend observed in the incidence of pleural mesothelioma and cancers in women is credibly due to their under diagnosis in the 1980-1997 period. The comparison between the French incidence and the American and British ones shows that the decreasing trend in incidence of mesothelioma and pleural cancers in French men since 2000 is potentially associated with a lower amphibole consumption and by the implementation of safety regulations at work from 1977. (c) 2009 UICC.
Published: 2009

29. Le cancer de la prostate en France en 2001: état des pratiques et facteurs associés à la réalisation d’une prostatectomie totale

Author: Jegu, Jérémie, Tretarre, Brigitte, Velten, Michel, Guizard, Anne-Valérie, Danzon, Arlette, Buemi, Antoine, Colonna, Marc, Kadi-Hanifi, A.-M., Ganry, Olivier, Molinie, Florence, Bara, Simona, Rebillard, Xavier, Grosclaude, Pascale, Registre des cancers du Tarn, Epidémiologie et Analyses en Santé Publique : risques, maladies chroniques et handicap (LEASP), Institut National de la Santé et de la Recherche Médicale (INSERM), FRANCIM, Réseau des registres français du cancer, Service d'urologie, and Clinique Beausoleil
Subjects: Adult, Aged, 80 and over, Male, Prostatectomy, Humans, Prostatic Neoplasms, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, France, Middle Aged, Aged
Abstract: International audience; INTRODUCTION: Prostate cancer was the most common cancer in men in France in 2005, and the second cause of male death from cancer. In this study, we analyzed clinical characteristics of patients with prostate cancer diagnosed in France in 2001 with a focus on therapeutic management of localized prostate cancers. PATIENTS AND METHODS: A total of 2181 cases of prostate cancer diagnosed in 2001 from 11 French counties covered by a cancer registry were analyzed. A descriptive study of the clinical characteristics of patients was performed. Parameters studied included age, county, TNM stage, PSA value, Gleason score, D'Amico prognostic group, Charlson's comorbidity index and initial treatment modalities. For localized cancers, multivariate logistic regression analysis identified factors associated with radical prostatectomy. RESULTS: The proportion of localized prostate cancer (T1 or T2) was 86.6 %. The use of invasive curative treatment (radical prostatectomy and radiotherapy) was 58.4 % for localized cancers. Significant differences in therapeutic management were found between counties. Radical prostatectomy was associated with age at diagnosis, D'Amico prognostic group and the presence of comorbidities. CONCLUSIONS: Most of prostate cancers diagnosed in France in 2001 were clinically localized and were treated by invasive therapy. The consequences of these practices remain to be determined given the limited evolution of many prostate cancers and the frequency of adverse events related to invasive treatments.
Published: 2009

30. La surveillance épidémiologique du risque de cancer

Author: Griffond-Boitier , Anne, Grandjean , Sébastien, Danzon , Arlette, Hägi , Mathieu, Théoriser et modéliser pour aménager ( ThéMA ), Université de Bourgogne ( UB ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Doubs Cancer Registry, University Hospital Jean Minjoz, Théoriser et modéliser pour aménager (UMR 6049) (ThéMA), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Clauzel, Céline, Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)-Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)
Subjects: [SHS.GEO] Humanities and Social Sciences/Geography, [SHS.GEO]Humanities and Social Sciences/Geography, [ SHS.GEO ] Humanities and Social Sciences/Geography
Abstract: La santé fait partie intégrante du bien être. Certaines maladies bénignes sont faciles à supporter, surtout si elles durent quelques jours seulement. En revanche, d'autres maladies sévères sont lourdes, tant sur le plan individuel que collectif. Le cancer est l'une d'entre elles ; les risques de mortalité sont variables selon l'organe touché, mais, dans tous les cas, une prise en charge par le corps médical s'impose durant des temps longs, souvent plusieurs années. Aussi, des réseaux de surveillance, où médecins et géographes collaborent, ont-ils vu le jour pour mieux cerner les causes de ce fléau ; et, peut-être, en réduire le taux d'incidence1.
Published: 2009

31. The performance of multiple imputation for missing covariate data within the context of regression relative survival analysis

Author: Giorgi, Roch, Belot, Aurélien, Gaudart, Jean, Launoy, Guy, Renseigné, Non, Danzon, Arlette, Chercheur indépendant, Service de Biostatistique, Hospices Civils de Lyon ( HCL ), Laboratoire de Biométrie et Biologie Evolutive ( LBBE ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique ( Inria ) -Centre National de la Recherche Scientifique ( CNRS ), Département des maladies chroniques et traumatismes, Institut de Veille Sanitaire (INVS), Laboratoire d'Enseignement et de Recherche sur le Traitement de l'Information Médicale ( LERTIM ), Université de la Méditerranée - Aix-Marseille 2, Cancers et Populations : Facteurs de Risque, Depistage, Pratiques Diagnostiques et Therapeutiques, Université de Caen Normandie ( UNICAEN ), Normandie Université ( NU ) -Normandie Université ( NU ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Hospices Civils de Lyon (HCL), Biostatistiques santé, Département biostatistiques et modélisation pour la santé et l'environnement [LBBE], Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Enseignement et de Recherche sur le Traitement de l'Information Médicale (LERTIM), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (UR 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: MESH: Registries, MESH : Male, MESH : Aged, [SDV.CAN]Life Sciences [q-bio]/Cancer, MESH: Prognosis, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, MESH: Proportional Hazards Models, MESH: Computer Simulation, MESH : Female, MESH : Middle Aged, MESH : France, MESH: Aged, MESH: Middle Aged, MESH: Humans, MESH : Prognosis, MESH : Humans, MESH : Models, Statistical, MESH : Proportional Hazards Models, MESH: Male, MESH: France, MESH : Computer Simulation, MESH: Survival Analysis, MESH : Colorectal Neoplasms, MESH : Survival Analysis, MESH: Female, MESH: Colorectal Neoplasms, MESH: Models, Statistical, MESH : Registries
Abstract: International audience; Relative survival assesses the effects of prognostic factors on disease-specific mortality when the cause of death is uncertain or unavailable. It provides an estimate of patients' survival, allowing for the effects of other independent causes of death. Regression-based relative survival models are commonly used in population-based studies to model the effects of some prognostic factors and to estimate net survival. Most often, studies focus on routinely collected prognostic factors for which the proportion of missing values is usually low (around 5 per cent). However, in some cases, additional factors are collected with a greater proportion of missingness. In the present article, we systematically assess the performance of multiple imputation in regression analysis of relative survival through a series of simulation experiments. According to the assumptions concerning the missingness mechanism (completely at random, at random, and not at random) and the missingness pattern (monotone, non-monotone), several strategies were considered and compared: all cases analysis, complete cases analysis, missing data indicator analysis, and multiple imputation by chained equations (MICE) analysis. We showed that MICE performs well in estimating the hazard ratios and the baseline hazard function when the missing mechanism is missing at random (MAR) conditionally on the vital status. In the situations where the missing mechanism was not MAR conditionally on vital status, complete case behaves consistently. As illustration, we used data of the French Cancer Registries on relative survival of patients with colorectal cancer.
Published: 2008

32. Rare skin cancer: a population-based cancer registry descriptive study of 151 consecutive cases diagnosed between 1980 and 2004

Author: Riou , Marie Odile, Fournier , E., Danzon , Arlette, Pelletier , Fabien, Humbert , Philippe, Aubin , François, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Département de dermatologie, Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Hôpital Saint-Jacques-Université de Franche-Comté ( UFC ), Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC ( HOTE GREFFON ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Etablissement français du sang [Bourgogne-France-Comté] ( EFS [Bourgogne-France-Comté] ) -Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Hôpital Saint-Jacques-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098) (RIGHT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS [Bourgogne-Franche-Comté])
Subjects: [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2008

33. Place de la radiothérapie pour cancer in situ du sein en France en 2003

Author: Billon-Delacour , S., Danzon , Arlette, Arveux , Patrick, Colonna , Marc, Ganry , Olivier, Grosclaude , Pascale, Guizard , Anne Valérie, Molinie , Florence, Tretarre , Brigitte, Velten , Michel, Lombrail , P., Bara , S., Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), FRANCIM, Réseau des registres français du cancer, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2008

34. Incidence des hémopathies lymphoïdes : Intérêt de l'utilisation de typologies territoriales pour l'étude des déterminants sociaux

Author: Hägi , Mathieu, Griffond-Boitier , Anne, Grandjean , Sébastien, Danzon , Arlette, Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Théoriser et modéliser pour aménager ( ThéMA ), Université de Bourgogne ( UB ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Doubs Cancer Registry, University Hospital Jean Minjoz, Institut National du cancer, Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Théoriser et modéliser pour aménager (UMR 6049) (ThéMA), Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)-Université de Franche-Comté (UFC), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)
Subjects: [SHS.GEO]Humanities and Social Sciences/Geography, [ SHS.GEO ] Humanities and Social Sciences/Geography
Abstract: 75
Published: 2008

35. Cancer Incidence and Mortality in France over the period 1980-2005

Author: Belot, R.A., Grosclaude, P., Bossard, N., Jouda, E., Benhamou, E., Delafosse, P., Guizard, A.V., Molinié, F., Danzon, Arlette, Cancer Registry of Isère, Département d'Ingénierie des Systèmes (ex SIS) ( DIS ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Département d'Ingénierie des Systèmes (ex SIS) (DIS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), and Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (UR 3181) (CEF2P / CARCINO)
Subjects: [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2008

36. Qualité de vie à long terme après un cancer du sein en France : étude comparative à partir de trois registres de cancer

Author: Velten, M., Klein, D., Lemoisson, E., Vinsu, C., Danzon, Arlette, Dalstein, V., Pozet, A., Guizard, A.V., Henry-Amar, M., Mercier, Mariette, Registre des cancers du Bas-Rhin, CRLCC Paul Strauss, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Laboratoire Pierre Süe ( LPS ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ), Interactions et dynamique des environnements de surface ( IDES ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (UR 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire Pierre Süe (LPS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Interactions et dynamique des environnements de surface (IDES), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), and Viala, Pascale
Subjects: [SDV.CAN] Life Sciences [q-bio]/Cancer, [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2008

37. Evolution of the survival of patients with a rectum cancer associated with recommendations for clinical practice study population 1984-2003 in the department of Doubs

Author: Paganelli, E., Danzon, Arlette, Vinsu, C., Bosset, Jean-François, Mercier, Mariette, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Laboratoire Pierre Süe ( LPS ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ), Interactions et dynamique des environnements de surface ( IDES ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire Pierre Süe (LPS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Interactions et dynamique des environnements de surface (IDES), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), and Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (UR 3181) (CEF2P / CARCINO)
Subjects: [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2008

38. Présentation des forums de discussion mis en place dans le cadre de la démarche qualité du réseau français des registres de cancer FRANCIM

Author: Coureau, G., Maurisset, S., Saves, M., Molinié, F., Delafosse, P., Sauvage, M., Danzon, Arlette, Cancer Registry of Isère, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2008

39. Incidence des hémopathies lymphoïdes

Author: Hägi, Mathieu, Griffond-Boitier, Anne, Grandjean, Sébastien, Danzon, Arlette, and Université de Bourgogne Franche-Comté, Théoriser et modéliser pour aménager (UMR 6049)
Subjects: [SHS.GEO] Humanities and Social Sciences/Geography
Published: 2008

40. Impact of socio-economic and surveillance characteristics on survival in patients with primary invasive breast cancer. A French population-based study

Author: Gentil-Brevet, Julie, Colonna, M., Danzon, Arlette, Grosclaude, P., Chaplain, Gilles, Velten, M., Bonnetain, Franck, Arveux, P., Viala, Pascale, Registre des Cancers du Sein et autres Cancers Gynécologiques de Côte d'Or - Breast and Gynaecologic Cancer Registry of Côte d’Or, Centre d'épidémiologie des populations ( CEP ), Université de Bourgogne ( UB ) -Centre Régional de Lutte contre le cancer - Centre Georges-François Leclerc ( CRLCC - CGFL ) -Université de Bourgogne ( UB ) -Centre Régional de Lutte contre le cancer - Centre Georges-François Leclerc ( CRLCC - CGFL ), Cancer Registry of Isère, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Registre des cancers du Bas-Rhin, CRLCC Paul Strauss, Centre d'épidémiologie des populations (CEP), Université de Bourgogne (UB)-Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER-UNICANCER-Université de Bourgogne (UB)-Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER-UNICANCER, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: [SDV.CAN] Life Sciences [q-bio]/Cancer, [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2008

41. Incidence of uveal melanoma in Europe

Author: Virgili , Gianni, Gatta , Gemma, Ciccolallo , Laura, Capocaccia , Riccardo, Biggeri , Annibale, Crocetti , Emanuele, Lutz , Jean-Michel, Paci , Eugenio, Renseigné , Non, Danzon , Arlette, Evaluative Epidemiology Unit, Fondazione IRCCS, Department of Statistics 'G. Parenti', University of Florence and Biostatistics Unit ISPO (Institute for Cancer Prevention and Research), Registre Genevois des Tumeurs, CHU Genève, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: Male, Uveal Neoplasms, MESH: Registries, Climate, MESH : Age Distribution, MESH : Aged, MESH : Child, Preschool, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, 0302 clinical medicine, MESH : Child, MESH: Child, MESH : Female, Registries, MESH: Incidence, Child, Melanoma, MESH : Sex Distribution, MESH: Aged, MESH: Middle Aged, Incidence (epidemiology), Incidence, MESH: Sex Distribution, MESH : Infant, Middle Aged, MESH : Adult, MESH: Climate, MESH: Infant, MESH : Incidence, 3. Good health, MESH: International Classification of Diseases, MESH : Uveal Neoplasms, Europe, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Child, Preschool, symbols, Female, Adult, medicine.medical_specialty, Adolescent, MESH: Melanoma, MESH : Male, Ocular Melanoma, MESH : Europe, MESH : Melanoma, [SDV.CAN]Life Sciences [q-bio]/Cancer, 03 medical and health sciences, symbols.namesake, Age Distribution, International Classification of Diseases, Internal medicine, MESH : Adolescent, MESH : International Classification of Diseases, medicine, Humans, MESH : Middle Aged, Poisson regression, Sex Distribution, MESH: Age Distribution, Aged, MESH: Adolescent, MESH: Humans, business.industry, MESH: Child, Preschool, MESH : Humans, Cancer, Infant, MESH: Adult, MESH : Climate, medicine.disease, Confidence interval, MESH: Male, Surgery, Cancer registry, Ophthalmology, 030221 ophthalmology & optometry, MESH: Uveal Neoplasms, Choroid, MESH: Europe, business, MESH: Female, International Classification of Diseases for Oncology, MESH : Registries
Abstract: International audience; PURPOSE: To estimate incidence rates of uveal melanoma in Europe from 1983 to 1994. DESIGN: Incidence analysis of data from cancer registries adhering to the European Cancer Registry-based study on survival and care of cancer patients (EUROCARE) (cases diagnosed from 1983 to 1994). PARTICIPANTS: Data of 6673 patients with ocular melanoma (as defined by International Classification of Diseases for Oncology morphology codes 8720 to 8780 [melanoma] and International Classification of Diseases 9 (ICD9) codes 190.0 [iris and ciliary body], 190.5 [retina], 190.6 [choroid], and 190.9 [unspecified ocular location]) from 33 cancer registries of 16 European countries. METHODS: Incidence rate ratios (IRRs) were obtained from a multilevel Poisson regression model. MAIN OUTCOME MEASURES: Incidence rates and IRRs associated with demographic and geographic variables. RESULTS: Standardized incidence rates increased from south to north across registries, from a minimum of 8 per million in Norway and Denmark. The inclusion of tumors with unspecified ocular location (code 190.9) increased incidence rates in most United Kingdom registries, but not in the other geographic areas, where this code was seldom used for uveal melanomas. Incidence increased noticeably up to age 55 (IRR, 1.46 per 5 years; 95% confidence interval [CI], 1.36-1.57) but leveled off after age 75 (IRR, 0.99 per 5 years; 95% CI, 0.93-1.05), with intermediate levels midway (IRR, 1.18 per 5 years; 95% CI, 1.12-1.23). It was also higher in males (IRR, 1.22; 95% CI, 1.16-1.28). Rates were stable during the study period, but a cohort effect was evidenced, accounting for higher incidence rates in people born during the period 1910 to 1935 (P = 0.005). Incidence increased with latitude (P = 0.008), which explained most differences in rates among areas. CONCLUSIONS: In this large series of uveal melanomas, we found stable incidence during the years 1983 to 1994. The north-to-south decreasing gradient supports the protective role of ocular pigmentation. European ophthalmologists should develop guidelines to standardize the coding of tumors treated conservatively using the ICD classification to improve the registration and surveillance of uveal melanoma by cancer registries.
Published: 2007

42. Compliance with good practice in early breast cancer treatment in relation to total national health expenditure

Author: Danzon , Arlette, C Sant M Lucca F Berrino T Aareleid E Ardanaz M Bielska-Lasota M Cirilli C Colonna M Contiero P Garau I Grosclaude P Hakulinen T Hédelin G Izarzugaza I Lotti B Martinez-Garcia C Paci E Peignaux K Plesko I Rachtan J Sigona A Storm H Torella-Ramos A Traina , Allemani, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2007

43. Survival for eight major cancers and all cancers combined for European adults diagnosed in 1995-99: results of the EUROCARE-4 study

Author: Berrino , Franco, De Angelis , Roberta, Sant , Milena, Rosso , Stefano, Bielska-Lasota , Magdalena, Lasota , Magdalena B, Coebergh , Jan W, Santaquilani , Mariano, Renseigné , Non, Danzon , Arlette, Department of Preventive & Predictive Medicine, Fondazione IRCCS-Istituto Nazionale dei Tumori, Department of Preventive and Predictive Medicine, Unit of Etiological Epidemiology and Prevention, Istituto Nazionale per lo Studio e la Cura dei Tumori, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: Survival, MESH: Registries, MESH : Aged, Disease, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, MESH: Aged, 80 and over, MESH: Health Surveys, 0302 clinical medicine, Survival data, Neoplasms, Epidemiology, MESH : Socioeconomic Factors, MESH: Neoplasms, 030212 general & internal medicine, Registries, MESH: Aged, Aged, 80 and over, education.field_of_study, MESH: Middle Aged, Relative survival, Health Care Costs, Middle Aged, MESH : Adult, major cancers, all cancers combined, European adults, 3. Good health, Europe, Oncology, MESH: Survival Analysis, 030220 oncology & carcinogenesis, MESH : Resource Allocation, MESH : Health Care Costs, Adult, MESH: Socioeconomic Factors, medicine.medical_specialty, Adolescent, Population, education, MESH : Europe, MESH : Health Surveys, MESH: Health Care Costs, [SDV.CAN]Life Sciences [q-bio]/Cancer, Resource Allocation, 03 medical and health sciences, MESH : Adolescent, medicine, Humans, MESH : Middle Aged, MESH : Aged, 80 and over, Survival analysis, Aged, MESH: Adolescent, MESH: Humans, business.industry, MESH : Humans, Cancer, MESH: Adult, medicine.disease, Health Surveys, Survival Analysis, MESH : Neoplasms, Socioeconomic Factors, MESH: Resource Allocation, MESH: Europe, MESH : Survival Analysis, business, MESH : Registries, Demography
Abstract: International audience; BACKGROUND: EUROCARE is the largest population-based cooperative study on survival of patients with cancer. The EUROCARE project aims to regularly monitor, analyse, and explain survival trends and between-country differences in survival. This report (EUROCARE-4) presents survival data for eight selected cancer sites and for all cancers combined, diagnosed in adult (aged >/=15 years) Europeans in 1995-99 and followed up until the end of 2003. METHODS: We analysed data from 83 cancer registries in 23 European countries on 2 699 086 adult cancer cases that were diagnosed in 1995-99 and followed up to December, 2003. We calculated country-specific and mean-weighted age-adjusted 5-year relative survival for eight major cancers. Additionally, case-mix-adjusted 5-year survival for all cancers combined was calculated by countries ranked by total national expenditure on health (TNEH). Changes to survival were analysed relative to cases diagnosed in 1990-94. FINDINGS: Mean age-adjusted 5-year relative survival for colorectal (53.8% [95% CI 53.3-54.1]), lung (12.3% [12.1-12.5]), breast (78.9% [78.6-79.2]), prostate (75.7% [75.2-76.2]), and ovarian (36.3% [35.7-37.0]) cancer was highest in Nordic countries (except Denmark) and central Europe, intermediate in southern Europe, lower in the UK and Ireland, and worst in eastern Europe. Survival for melanoma (81.6% [81.0-82.3]), cancer of the testis (94.2% [93.4-95.0]), and Hodgkin's disease (80.0% [79.0-81.0]) varied little with geography. All-cancer survival correlated with TNEH for most countries. Denmark and UK had lower all-cancer survival than countries with similar TNEH; Finland had high all-cancer survival, but moderate TNEH. Survival increased and intercountry survival differences narrowed between the data for 1990-94 and 1995-99 for, notably, Hodgkin's disease (range 66.1-82.9 [IQR 72.2-78.6] vs 74.0-83.9 [78.6-81.9]), colorectal (29.4-56.7 [45.8-54.1] vs 38.8-59.7 [50.7-57.5]), and breast (61.7-82.7 [72.3-78.3] vs 69.3-87.6 [76.6-82.7]) sites. INTERPRETATION: Increases in survival and decreases in geographic differences over time, which are mainly due to improvements in health-care services in countries with poor survival, might indicate better cancer care. Wealthy countries with high TNEH generally had good cancer outcomes, but those with conspicuously worse outcomes than those with similar TNEH might not be allocating health resources efficiently.
Published: 2007

44. Recent cancer survival in Europe: a 2000-02 period analysis of EUROCARE-4 data

Author: Verdecchia , Arduino, Francisci , Silvia, Brenner , Hermann, Gatta , Gemma, Micheli , Andrea, Mangone , Lucia, Kunkler , Ian, Renseigné , Non, Danzon , Arlette, Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Evaluative Epidemiology Unit, Fondazione IRCCS, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)
Subjects: Oncology, medicine.medical_specialty, MESH: Registries, MESH: Age of Onset, MESH : Europe, MESH : Health Surveys, [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, MESH: Health Surveys, Internal medicine, Neoplasms, Epidemiology of cancer, Medicine, Humans, MESH: Neoplasms, 030212 general & internal medicine, Registries, Age of Onset, Stomach cancer, Thyroid cancer, Survival analysis, Gynecology, MESH: Humans, Relative survival, business.industry, cancer survival - period analysis, MESH : Humans, Cancer, MESH : SEER Program, medicine.disease, Health Surveys, Survival Analysis, MESH : Neoplasms, 3. Good health, MESH : Age of Onset, Eastern european, Europe, 030220 oncology & carcinogenesis, MESH: Survival Analysis, MESH: SEER Program, MESH: Europe, MESH : Survival Analysis, business, MESH : Registries, SEER Program
Abstract: International audience; BACKGROUND: Traditional cancer-survival analyses provide data on cancer management at the beginning of a study period, and are often not relevant to current practice because they refer to survival of patients treated with older regimens that might no longer be used. Therefore, shortening the delay in providing survival estimates is desirable. Period analysis can estimate cancer survival by the use of recent data. We aimed to apply the period-analysis method to data that were collected by European cancer registries to estimate recent survival by country and cancer site, and to assess survival changes in Europe. We also compared our findings with data on cancer survival in the USA from the US SEER (Surveillance, Epidemiology, and End Results) programme. METHODS: We analysed survival data for patients diagnosed with cancer in 2000-02, collected from 47 of the European cancer registries participating in the EUROCARE-4 study. 5-year period relative survival for patients diagnosed in 2000-02 was estimated as the product of interval-specific relative survival values of cohorts with different lengths of follow-up. 5-year survival profiles for patients diagnosed in 2000-02 were estimated for the European mean and for five European regions, and findings were compared with US SEER registry data for patients diagnosed in 2000-02. A 5-year survival profile for patients diagnosed in 1991-2002 and a 10-year survival profile for patients diagnosed in 1997-2002 were also estimated by the period method for all malignancies, by geographical area, and by cancer site. FINDINGS: For all cancers, age-adjusted 5-year period survival improved for patients diagnosed in 2000-02, especially for patients with colorectal, breast, prostate, and thyroid cancer, Hodgkin's disease, and non-Hodgkin lymphoma. The European mean age-adjusted 5-year survival calculated by the period method for 2000-02 was high for testicular cancer (97.3% [95% CI 96.4-98.2]), melanoma (86.1% [84.3-88.0]), thyroid cancer (83.2% [80.9-85.6]), Hodgkin's disease (81.4% [78.9-84.1]), female breast cancer (79.0% [78.1-80.0]), corpus uteri (78.0% [76.2-79.9]), and prostate cancer (77.5% [76.5-78.6]); and low for stomach cancer (24.9% [23.7-26.2]), chronic myeloid leukaemia (32.2% [29.0-35.7]), acute myeloid leukaemia (14.8% [13.4-16.4]), and lung cancer (10.9% [10.5-11.4]). Survival for patients diagnosed in 2000-02 was generally highest for those in northern European countries and lowest for those in eastern European countries, although, patients in eastern European had the highest improvement in survival for major cancer sites during 1991-2002 (colorectal cancer from 30.3% [28.3-32.5] to 44.7% [42.8-46.7]; breast cancer from 60% [57.2-63.0] to 73.9% [71.7-76.2]; for prostate cancer from 39.5% [35.0-44.6] to 68.0% [64.2-72.1]). For all solid tumours, with the exception of stomach, testicular, and soft-tissue cancers, survival for patients diagnosed in 2000-02 was higher in the US SEER registries than for the European mean. For haematological malignancies, data from US SEER registries and the European mean were comparable in 2000-02, except for non-Hodgkin lymphoma. INTERPRETATION: Cancer-service infrastructure, prevention and screening programmes, access to diagnostic and treatment facilities, tumour-site-specific protocols, multidisciplinary management, application of evidence-based clinical guidelines, and recruitment to clinical trials probably account for most of the differences that we noted in outcomes.
Published: 2007

45. [Risk of second cancer after germinal cell testicular cancer: study from the data of Doubs cancer registry]

Author: Servagi-Vernat, Stéphanie, Langlois-Jacques, Carole, Bontemps, Patrick, Cléro, Enora, Bosset, Jean-François, Danzon, Arlette, Association Générale des Laboratoires d'Analyse de l'Environnement (AGLAE), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Association Générale des Laboratoires d'Analyse de l'Environnement ( AGLAE ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), and Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC )
Subjects: Adult, Male, MESH: Neoplasms, Second Primary, endocrine system diseases, MESH: Registries, MESH : Male, MESH : Aged, [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, MESH: Aged, 80 and over, Testicular Neoplasms, MESH : Neoplasms, Germ Cell and Embryonal, Humans, MESH : Middle Aged, Registries, MESH : Neoplasms, Second Primary, MESH : Testicular Neoplasms, MESH : Aged, 80 and over, MESH : France, Aged, MESH: Testicular Neoplasms, Aged, 80 and over, MESH: Aged, MESH: Humans, MESH: Middle Aged, MESH : Humans, Neoplasms, Second Primary, MESH: Adult, Middle Aged, Neoplasms, Germ Cell and Embryonal, MESH : Adult, MESH: Male, MESH: France, MESH: Neoplasms, Germ Cell and Embryonal, France, MESH : Registries
Abstract: International audience; Testicular cancer, both seminoma and nonseminoma tumours, account for 1 to 1.5 % of male cancers. Many studies have shown that the risk of a second cancer after radiotherapy is dependent on the size of the exposure fields and the strength of delivered doses of radiotherapy. According to the literature, the relative risk of second cancer among patients treated by irradiation for seminoma limited to the testis varies from 1.5 to 1.9. We conducted a retrospective epidemiological study to measure the risk of second cancer in a population treated for both seminoma and nonseminoma tumours. The study period included patients who were diagnosed from 1978 to 2002. Data were provided by the Doubs cancer registry. Among these 291 cases of testicular cancer, we found 11 cases of second cancer after 157 seminomas (stomach, lungs, testis, ORL, kidney and oesophagus), and 3 cases after 134 nonseminomas (thyroid, kidney and testis). We found a high risk for second pulmonary and testicular cancers (standardised incidence ratio almost statistically significant). While our results are not conclusive regarding the etiology of these second cancers, they do form a useful, comparative basis for further study. They constitute the first step of a study that will be carried out on the risk related to radiation after orchidectomy.
Published: 2007

46. Contribution d'un registre départemental de cancer à l'étude de la prise en charge régionale des patients : l'exemple des marqueurs des leucémies lymphoïdes chroniques

Author: Rymzhanova, Raouchan, Schillinger, Françoise, Grandjean, S., Garnache-Ottou, F., Griffond-Boitier, Anne, Maynadié, M., Vuitton, Dominique A, Danzon, Arlette, Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), EFS Rhône-Alpes, EFS, Théoriser et modéliser pour aménager (UMR 6049) (ThéMA), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB), WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Théoriser et modéliser pour aménager ( ThéMA ), Université de Bourgogne ( UB ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), and Viala, Pascale
Subjects: [SDV.CAN] Life Sciences [q-bio]/Cancer, [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2007

47. Le lymphome gastrique en France : incidence et survie

Author: Danzon , Arlette, Belot , A., Gossart-Dupont , A., Deconninck , Eric, Carbonel , F., Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), UFR Sciences médicales et pharmaceutiques, Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), and Université de Franche-Comté ( UFC )
Subjects: [SDV.CAN]Life Sciences [q-bio]/Cancer, [ SDV.CAN ] Life Sciences [q-bio]/Cancer
Published: 2007

48. [Epidemiology of urogenital cancers in France]

Author: Rébillard, Xavier, Tretarre, Brigitte, Renseigné, Non, Danzon, Arlette, Service d'urologie, Clinique Beausoleil, FRANCIM, Réseau des registres français du cancer, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), and Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC )
Subjects: MESH: Humans, Incidence, MESH : Humans, [SDV.CAN]Life Sciences [q-bio]/Cancer, Survival Analysis, MESH : Incidence, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, MESH: France, MESH: Survival Analysis, Humans, MESH : Urogenital Neoplasms, France, MESH: Incidence, MESH : Survival Analysis, MESH : France, MESH: Urogenital Neoplasms, Urogenital Neoplasms
Abstract: International audience; Estimates of cancer incidence and mortality in France as well as survival data are published by the cancer registry network (Francim). In 2000, the number of new cancer cases was almost 280,000 in France. This number has been gradually increasing, partly due to population aging. The proportion of urological cancers is increasing as well, as a consequence of the marked increase in number of prostate cancers. The estimated number of new cases for the 4 main urological cancers in 2000 reached 61,174, distributed as follows: 40,310 prostate cancers, 10,771 bladder cancers, 8,293 kidney cancers and 1,800 testis cancers. Urological tumours represented at the time 22% of new cancer cases in France: 35% of male cancers (56,402 /161,025) and 4% of female cancers (4,772/117,228). The relative five-year survival for prostate cancers is high: 80%. It is below that of testis cancers (95% after 5 years), but higher than that of kidney cancers (64% in men and 63% in women after five years). Of all urological cancers, bladder cancers have the worst prognosis, since the relative five-year survival is 60% in men and especially 50% in women.
Published: 2007

49. Influence des conditions de vie sur l'incidence des cancers

Author: Griffond-Boitier , Anne, Danzon , Arlette, Bérion , Pascal, Grandjean , Sébastien, Fournier , E., Provitolo , Damienne, Rymzhanova , Raouchan, Stephenson , Richard, Tannier , Cécile, Coig, Aurélie, Théoriser et modéliser pour aménager (UMR 6049) (ThéMA), Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Registre des tumeurs du Doubs et du Territoire de Belfort [CHRU Besançon], Pôle cancérologie (CHRU Besançon), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB), Théoriser et modéliser pour aménager ( ThéMA ), Université de Bourgogne ( UB ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Registre des tumeurs du Doubs, Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), and Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC )
Subjects: [SHS.GEO] Humanities and Social Sciences/Geography, Géographie de la santé, cancer, [SHS.GEO]Humanities and Social Sciences/Geography, [ SHS.GEO ] Humanities and Social Sciences/Geography
Published: 2007

50. [Incidence and mortality of central nervous system tumors in France: trends over the period 1978-2000 and influence of registration practices on results]

Author: Ménégoz, F., Martin, E., Danzon, Arlette, Mathieu-Daudé, H., Guizard, A.-V., Macé-Lesec'H, J., Raverdy, N., Pasquier, B., Service de Dermatologie, Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Hôpital Saint-Jacques, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Institut Fourier ( IF ), Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ), Viala, Pascale, Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Hôpital Saint-Jacques, Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Université de Franche-Comté (UFC), Institut Fourier (IF), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Hôpital Saint-Jacques, Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Institut Fourier (IF ), and Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])
Subjects: Male, MESH: Survival Rate, MESH: Registries, MESH : Retrospective Studies, MESH : Sex Factors, MESH : Male, MESH : Aged, [SDV.CAN]Life Sciences [q-bio]/Cancer, MESH : Central Nervous System Neoplasms, MESH: Central Nervous System Neoplasms, [ SDV.CAN ] Life Sciences [q-bio]/Cancer, Central Nervous System Neoplasms, Sex Factors, MESH: Sex Factors, [SDV.CAN] Life Sciences [q-bio]/Cancer, MESH: Risk Factors, Risk Factors, Humans, MESH : Female, MESH : Middle Aged, MESH: Incidence, Registries, MESH : France, Aged, Retrospective Studies, MESH: Aged, MESH: Humans, MESH: Middle Aged, Incidence, MESH : Humans, MESH: Retrospective Studies, Middle Aged, MESH : Survival Rate, MESH : Risk Factors, MESH: Male, MESH : Incidence, MESH: France, Survival Rate, Female, France, MESH: Female, MESH : Registries
Abstract: International audience; BACKGROUND: In France, cancer incidence figures are produced by cancer registries covering only 13.5% to 16% of the whole population of the country. Thus, to produce national figures, estimates have to be computed. Registration disparities between registries concerning tumors of the Central Nervous System (CNS) could have biased these estimates. METHODS: National estimates are based on modelling of the incidence/mortality ratio. The most recent estimations for year 2000 were calculated by the French Cancer Registry Network (FRANCIM) and the department of biostatistics of Lyon University Hospital. Since benign tumors are not recorded in some cancer registries, a new estimate of the incidence of CNS tumors was produced by estimating the number of benign tumors in these registries. RESULTS: In 2000 in France, the number of estimated cases of CNS tumors was 2697 in men and 2602 in women, with incidence rates (World standard) of 7.4 and 6.4 per 100,000 respectively. The incidence increased between 1978 and 2000, on an average by 2.25% per year in men and 3.01% per year in women. However, these estimates do not provide a correct picture of CNS incidence. First of all, pathological diagnoses are not performed in 3.5%-27.5% of the patients with CNS tumors registered in French registries. Second, figures for benign tumors (mainly meningiomas) were provided by only two of nine cancer registries. If benign tumors had been registered by all cancer registries, computed incidence would have increased by 12% for men and 26% for women. CONCLUSION: Incidence of CNS tumors is increasing in France, as in many other countries. To improve comparability with other countries, French cancer registries should also collect data on benign tumors. The discrepancies observed between registries in the proportion of patients without information on histology show differences in diagnostic practices and should be the starting point for a survey on this topic.
Published: 2006

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