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1. Accuracy of cobas MTB and MTB-RIF/INH for Detection of Mycobacterium tuberculosis and Drug Resistance

Author

Ciobanu, Nelly, Singh Chadha, Sarabijt, Codreanu, Alexandru, Das, Dasarathi, Kahamba, Trish, Kar, Itishree, Macé, Aurélien, Mohanty, Jyoti, Nabeta, Pamela, Kranzer, Katherina, Ongarello, Stefano, Pattanaik, Archana, Romancenco, Elena, Sarin, Sanjay, Singh, Lyndel, Singh, Sunita, Turcan, Nadia, de Vos, Margaretha, David, Anura, Duraisamy, Karthickeyan, Nadarajan, Darshaalini, Noroc, Ecaterina, Penn-Nicholson, Adam, Crudu, Valeriu, Giri, Sidhartha, Maurer, Florian P., Pati, Sanghamitra, Stevens, Wendy, Scott, Lesley, Turuk, Jyotimayee, Schumacher, Samuel G., and Ruhwald, Morten

Published
2024
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3. Prevalence and factors associated with tuberculosis infection in India

Author

Selvaraju, Sriram, Velayutham, Banurekha, Rao, Raghuram, Rade, Kiran, Thiruvengadam, Kannan, Asthana, Smita, Balachandar, Rakesh, Bangar, Sampada Dipak, Bansal, Avi Kumar, Bhat, Jyothi, Chopra, Vishal, Das, Dasarathi, Dutta, Shantha, Devi, Kangjam Rekha, Dwivedi, Gaurav Raj, Kalliath, Arshad, Laxmaiah, Avula, Madhukar, Major, Mahapatra, Amarendra, Mohanty, Suman Sundar, Rangaraju, Chethana, Turuk, Jyotirmayee, Menon, Pradeep Aravindan, Krishnan, Rajendran, Singh, Manjula, Sekar, Krithikaa, Robinson, Aby, Turuk, Alka, Krishnan, Nivethitha N., Srinivasan, Nivetha, Rexy, Catherine, Suresh, M., Hanna, Luke Elizabeth, Choudhury, Avijit H, Parmar, Malik, Ramachandran, Ranjani, Kumar, Nishant, Joshi, Rajendra Panduranga, Narasimhaiah, Somashekar, Chandrasekaran, Padmapriyadarsini, Khan, A.M., Panda, Samiran, and Bhargava, Balram

Published
2023
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5. Accuracy of cobas MTB and MTB-RIF/INH for detection of M. tuberculosis and drug resistance

Author

de Vos, Margaretha, primary, David, Anura, additional, Duraisamy, Karthickeyan, additional, Nadarajan, Darshaalini, additional, Noroc, Ecaterina, additional, Penn-Nicholson, Adam, additional, Crudu, Valeriu, additional, Giri, Sidhartha, additional, Maurer, Florian P., additional, Pati, Sanghamitra, additional, Stevens, Wendy, additional, Scott, Lesley, additional, Turuk, Jyotimayee, additional, Schumacher, Samuel G., additional, Ruhwald, Morten, additional, Ciobanu, Nelly, additional, Chadha, Sarabijt Singh, additional, Codreanu, Alexandru, additional, Das, Dasarathi, additional, Kahamba, Trish, additional, Kar, Itishree, additional, Macé, Aurélien, additional, Mohanty, Jyoti, additional, Nabeta, Pamela, additional, Kranzer, Katherina, additional, Ongarello, Stefano, additional, Pattanaik, Archana, additional, Romancenco, Elena, additional, Sarin, Sanjay, additional, Singh, Lyndel, additional, Singh, Sunita, additional, and Turcan, Nadia, additional

Published
2024
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6. Diagnostic Accuracy of The TrueNat MTB/RIF Assay And Comparison With The Reference Standards To Detect Pulmonary Tuberculosis And Rifampicin Resistance in Sputum Samples From Patients Attending A Tertiary Care Hospital in Bhubaneswar, India

Author

Barik, Braja Sundar, primary, Das, Shritam, additional, Singh, Khusbu, additional, Chandan, Sudatta, additional, Kumar Swain, Subrat, additional, Nayak, Prasanti, additional, Mishra, Omkar Abadesh, additional, Hussain, Tahziba, additional, Das, Dasarathi, additional, and Pati, Sanghamitra, additional

Published
2024
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7. SARS-CoV-2 seroprevalence among the general population and healthcare workers in India, December 2020–January 2021

Author

Anand, Tanu, Babu, Giridhara R., Chauhan, Himanshu, Dikid, Tanzin, Gangakhedkar, Raman R., Kant, Shashi, Kulkarni, Sanket, Muliyil, J.P., Pandey, Ravindra Mohan, Sarkar, Swarup, Shah, Naman, Shrivastava, Aakash, Singh, Sujeet K., Zodpe, Sanjay, Hindupur, Anusha, Asish, P.R., Chellakumar, M., Chokkalingam, D., Dasgupta, Sauvik, Gowtham, M.M.E., Jose, Annamma, Kalaiyarasi, K., Karthik, N.N., Karunakaran, T., Kiruthika, G., Dinesh Kumar, H., Sarath Kumar, S., Sarath Kumar, M.P., Michaelraj, E., Pradhan, Josephine, Arun Prasath, E.B., Gladys Angelin Rachel, D., Rani, Sudha, Rozario, Amanda, Sivakumar, R., Gnana Soundari, P., Sujeetha, K., Vinod, Arya, Murhekar, Manoj V., Bhatnagar, Tarun, Thangaraj, Jeromie Wesley Vivian, Saravanakumar, V., Kumar, Muthusamy Santhosh, Selvaraju, Sriram, Rade, Kiran, Kumar, C.P. Girish, Sabarinathan, R., Turuk, Alka, Asthana, Smita, Balachandar, Rakesh, Bangar, Sampada Dipak, Bansal, Avi Kumar, Chopra, Vishal, Das, Dasarathi, Deb, Alok Kumar, Devi, Kangjam Rekha, Dhikav, Vikas, Dwivedi, Gaurav Raj, Khan, S. Muhammad Salim, Kumar, M. Sunil, Laxmaiah, Avula, Madhukar, Major, Mahapatra, Amarendra, Rangaraju, Chethana, Turuk, Jyotirmayee, Yadav, Rajiv, Andhalkar, Rushikesh, Arunraj, K., Bharadwaj, Dinesh Kumar, Bharti, Pravin, Bhattacharya, Debdutta, Bhat, Jyothi, Chahal, Ashrafjit S., Chakraborty, Debjit, Chaudhury, Anshuman, Deval, Hirawati, Dhatrak, Sarang, Dayal, Rakesh, Elantamilan, D., Giridharan, Prathiksha, Haq, Inaamul, Hudda, Ramesh Kumar, Jagjeevan, Babu, Kalliath, Arshad, Kanungo, Srikanta, Krishnan, Nivethitha N., Kshatri, Jaya Singh, Kumar, Alok, Kumar, Niraj, Kumar, V.G. Vinoth, Lakshmi, G.G.J. Naga, Mehta, Ganesh, Mishra, Nandan Kumar, Mitra, Anindya, Nagbhushanam, K., Nimmathota, Arlappa, Nirmala, A.R., Pandey, Ashok Kumar, Prasad, Ganta Venkata, Qurieshi, Mariya Amin, Reddy, Sirasanambatti Devarajulu, Robinson, Aby, Sahay, Seema, Saxena, Rochak, Sekar, Krithikaa, Shukla, Vijay Kumar, Singh, Hari Bhan, Singh, Prashant Kumar, Singh, Pushpendra, Singh, Rajeev, Srinivasan, Nivetha, Varma, Dantuluri Sheethal, Viramgami, Ankit, Wilson, Vimith Cheruvathoor, Yadav, Surabhi, Yadav, Suresh, Zaman, Kamran, Chakrabarti, Amit, Das, Aparup, Dhaliwal, R.S., Dutta, Shanta, Kant, Rajni, Khan, A.M., Narain, Kanwar, Narasimhaiah, Somashekar, Padmapriyadarshini, Chandrasekaran, Pandey, Krishna, Pati, Sanghamitra, Patil, Shripad, Rajkumar, Hemalatha, Ramarao, Tekumalla, Sharma, Y.K., Singh, Shalini, Panda, Samiran, Reddy, D.C.S., and Bhargava, Balram

Published
2021
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8. SARS-CoV-2 antibody seroprevalence in India, August–September, 2020: findings from the second nationwide household serosurvey

Author

Andhalkar, Rushikesh, Chaudhury, Anshuman, Deval, Hirawati, Dhatrak, Sarang, Gupta, Rajeev Ranjan, Ilayaperumal, Ezhilarasan, Jagjeevan, Babu, Jha, Ramesh Chandra, Kiran, K, Krishnan, Nivethitha N, Kumar, Alok, Kumar, VG Vinoth, Nagbhushanam, K, Nimmathota, Arlappa, Pandey, Ashok Kumar, Pawar, Harpreet Singh, Rathore, Kushal Singh, Robinson, Aby, Singh, Hari Bhan, Wilson, Vimith Cheruvathoor, Yadav, Ashwini, Yadav, Rajiv, Karunakaran, T, Pradhan, Josephine, Sivakumar, T, Jose, Annamma, Kalaiyarasi, K, Dasgupta, Sauvik, Anusha, R, Anand, Tanu, Babu, Giridhara R, Chauhan, Himanshu, Dikid, Tanzin, Gangakhedkar, Raman R, Kant, Shashi, Kulkarni, Sanket, Muliyil, J P, Pandey, Ravindra Mohan, Sarkar, Swarup, Shrivastava, Aakash, Singh, Sujeet K, Zodpey, Sanjay, Das, Aparup, Das, Pradeep, Dutta, Shanta, Kant, Rajni, Narain, Kanwar, Narasimhaiah, Somashekar, Pati, Sanghamitra, Patil, Shripad, Rajkumar, Hemalatha, Ramarao, Tekumalla, Sarkar, Kamalesh, Singh, Shalini, Toteja, Gurudayal S, Zaman, Kamran, Murhekar, Manoj V, Bhatnagar, Tarun, Selvaraju, Sriram, Saravanakumar, V, Thangaraj, Jeromie Wesley Vivian, Shah, Naman, Kumar, Muthusamy Santhosh, Rade, Kiran, Sabarinathan, R, Asthana, Smita, Balachandar, Rakesh, Bangar, Sampada Dipak, Bansal, Avi Kumar, Bhat, Jyothi, Chopra, Vishal, Das, Dasarathi, Deb, Alok Kumar, Devi, Kangjam Rekha, Dwivedi, Gaurav Raj, Khan, S Muhammad Salim, Kumar, C P Girish, Kumar, M Sunil, Laxmaiah, Avula, Madhukar, Major, Mahapatra, Amarendra, Mohanty, Suman Sundar, Rangaraju, Chethana, Turuk, Alka, Baradwaj, Dinesh Kumar, Chahal, Ashrafjit S, Debnath, Falguni, Haq, Inaamul, Kalliath, Arshad, Kanungo, Srikanta, Kshatri, Jaya Singh, Lakshmi, G G J Naga, Mitra, Anindya, Nirmala, A R, Prasad, Ganta Venkata, Qurieshi, Mariya Amin, Sahay, Seema, Sangwan, Ramesh Kumar, Sekar, Krithikaa, Shukla, Vijay Kumar, Singh, Prashant Kumar, Singh, Pushpendra, Singh, Rajeev, Varma, Dantuluri Sheethal, Viramgami, Ankit, Panda, Samiran, Reddy, D C S, and Bhargava, Balram

Published
2021
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9. Effectiveness of food supplement on treatment outcomes and quality of life in pulmonary tuberculosis: Phased implementation approach.

Author

Mahapatra, Amarendra, Thiruvengadam, Kannan, Nair, Dina, Padmapriyadarsini, Chandrasekaran, Thomas, Beena, Pati, Sanghamitra, Bulliyya, Gandham, Das, Dasarathi, Chowdhury, Jayeeta, Bang, Anand, and Swaminathan, Soumya

Subjects
DIETARY supplements, TUBERCULOSIS, QUALITY of life, TREATMENT effectiveness, END of treatment, NUTRITIONAL status
Abstract

Background: By encouraging treatment adherence and lowering mortality, dietary supplements can serve as adjuvant therapy for the success of medical interventions. We determined the effect of locally accessible food supplements on treatment outcomes, and health-related quality of life in patients with pulmonary tuberculosis initiating anti-tuberculosis treatment (ATT) in Odisha, India. Method: Between September 2017 and December 2018, implementation research in patients with newly diagnosed sputum smear-positive pulmonary tuberculosis initiating ATT in five districts of the tribal belt of Odisha, offered food supplements along with ATT in a phased manner. Clinical symptoms, anthropometry, sputum for M. tuberculosis (M. tb), health-related quality of life and return to normal function were assessed periodically, and favourable treatment outcome (cure or treatment completed) was measured at the end of treatment. The effect of the food supplement on unfavorable outcomes (treatment failure, death, or lost-to-follow-up) was modelled using mixed-effects Poisson regression to determine the risk factors. Results: Among the 761 participants enrolled, 614 participants received the food supplement and 147 did not receive the food supplement. Among the 614 participants in the supplement group, 537 (87%) had a favorable outcome and among the 147 participants in the no-supplement group, 113 (77%) had a favorable outcome (p = 0.0017). Higher age (>55 years) [aRR = 2.1(95% CI: 1.1–3.8)], male gender [aRR = 1.7(95% CI: 1.2–2.9)], and smear grading ≥2+ [aRR = 1.5 (95% CI: 1.1–2.2)] were associated with unfavorable treatment outcomes. Nutritional status, quality of life and lung health showed significant improvement from baseline in the supplement group. Conclusion: Improvement in the nutritional status of the patient can be considered a predictor of treatment success rates. Early food supplementation has a positive impact on the nutritional status. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Drug susceptibility testing and line probe assay of first‑line anti‑tuberculosis drugs among presumptive tuberculosis patients attending a secondary care hospital in Bhubaneswar.

Author

Singh, Khusbu, Barik, Braja S., Das, Shritam, Hussain, Tahziba, Gupta, Bhawna, Das, Dasarathi, and Pati, Sanghamitra

Subjects
TUBERCULOSIS patients, DRUG resistance, SECONDARY care (Medicine), GENETIC mutation, HOSPITAL care
Abstract

Background: Pyrazinamide (PZA) is important for identification in multi‑drug‑resistant tuberculosis patients before starting therapy. PZA drug susceptibility testing (DST) is essential for the management of drug‑resistant and susceptible TB patients. Aims: The degree of drug resistance among TB patients and discrepancy between DST results of the phenotype and genotype were assessed. Materials and Methods: Socio‑demographic and clinical profiles of TB patients recruited in the study were documented. Sputum samples were processed for diagnosis using TrueNat Xpert MTB, TrueNat Xpert MTB Plus, and MGIT culture. Results: Rifampicin (RIF) line probe assay (LPA) showed the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 100%, whereas isoniazid (INH) LPA testing showed a sensitivity of 85.7%, a specificity and PPV of 100%, and NPV of 94.8%. The gene mutation for RIF resistance was between the codon, 530–533 of rpoB gene, and that for INH resistance was at the codon, 315 of katG gene. Conclusion: Our findings demonstrated high prevalence of mono‑ and poly‑drug resistance as well as pyrazinamide resistance. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Recurrence of pulmonary tuberculosis in India: Findings from the 2019–2021 nationwide community-based TB prevalence survey

Author

Giridharan, Prathiksha, primary, Selvaraju, Sriram, additional, Rao, Raghuram, additional, Rade, Kiran, additional, Thiruvengadam, Kannan, additional, Asthana, Smita, additional, Balachandar, Rakesh, additional, Dipak Bangar, Sampada, additional, Bansal, Avi Kumar, additional, Bhat, Jyothi, additional, Chakraborty, Debjit, additional, Chopra, Vishal, additional, Das, Dasarathi, additional, Dutta, Shanta, additional, Rekha Devi, Kangjam, additional, Kumar, Sunil, additional, Laxmaiah, Avula, additional, Madhukar, Major, additional, Mahapatra, Amarendra, additional, Mohanty, Suman Sundar, additional, Rangaraju, Chethana, additional, Turuk, Jyotirmayee, additional, Zaman, Kamran, additional, Krishnan, Rajendran, additional, Shanmugam, Sivakumar, additional, Kumar, Nishant, additional, Panduranga Joshi, Rajendra, additional, Narasimhaiah, Somashekar, additional, Chandrasekaran, Padmapriyadarsini, additional, Gangakhedkar, Raman R., additional, and Bhargava, Balram, additional

Published
2023
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12. Pleural tuberculosis in Bhubaneswar, Odisha, during 2016 to 2022

Author

Mohanty, Triyambakesh, primary, Kumar, Sujeet, additional, Rout, Sunil Swick, additional, Kar, Sarita, additional, Bal, Himadri Bhusan, additional, Turuk, Jyotirmayee, additional, Das, Dasarathi, additional, Sundaray, Sooman, additional, Pati, Sanghamitra, additional, and Giri, Sidhartha, additional

Published
2023
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13. Seroprevalence of IgG antibodies against SARS-CoV-2 among the general population and healthcare workers in India, June-July 2021: A population-based cross-sectional study

Author

Murhekar, Manoj V., Bhatnagar, Tarun, Thangaraj, Jeromie Wesley Vivian, Saravanakumar, V., Santhosh Kumar, Muthusamy, Selvaraju, Sriram, Rade, Kiran, Kumar, C. P. Girish, Sabarinathan, R., Asthana, Smita, Balachandar, Rakesh, Bangar, Sampada Dipak, Bansal, Avi Kumar, Bhat, Jyothi, Chakraborty, Debjit, Chopra, Vishal, Das, Dasarathi, Devi, Kangjam Rekha, Dwivedi, Gaurav Raj, Jain, Agam, Khan, S. Muhammad Salim, Kumar, M. Sunil, Laxmaiah, Avula, Madhukar, Major, Mahapatra, Amarendra, Ramesh, Talluri, Rangaraju, Chethana, Turuk, Jyotirmayee, Yadav, Suresh, and Bhargava, Balram

Subjects
Immunoglobulin G -- Statistics -- Health aspects, Medical personnel -- Statistics -- Health aspects, Biological sciences
Abstract

Background India began COVID-19 vaccination in January 2021, initially targeting healthcare and frontline workers. The vaccination strategy was expanded in a phased manner and currently covers all individuals aged 18 years and above. India experienced a severe second wave of COVID-19 during March-June 2021. We conducted a fourth nationwide serosurvey to estimate prevalence of SARS-CoV-2 antibodies in the general population aged [greater than or equal to]6 years and healthcare workers (HCWs). Methods and findings We did a cross-sectional study between 14 June and 6 July 2021 in the same 70 districts across 20 states and 1 union territory where 3 previous rounds of serosurveys were conducted. From each district, 10 clusters (villages in rural areas and wards in urban areas) were selected by the probability proportional to population size method. From each district, a minimum of 400 individuals aged [greater than or equal to]6 years from the general population (40 individuals from each cluster) and 100 HCWs from the district public health facilities were included. The serum samples were tested for the presence of IgG antibodies against S1-RBD and nucleocapsid protein of SARS-CoV-2 using chemiluminescence immunoassay. We estimated the weighted and test-adjusted seroprevalence of IgG antibodies against SARS-CoV-2, along with 95% CIs, based on the presence of antibodies to S1-RBD and/or nucleocapsid protein. Of the 28,975 individuals who participated in the survey, 2,892 (10%) were aged 6-9 years, 5,798 (20%) were aged 10-17 years, and 20,285 (70%) were aged [greater than or equal to]18 years; 15,160 (52.3%) participants were female, and 21,794 (75.2%) resided in rural areas. The weighted and test-adjusted prevalence of IgG antibodies against S1-RBD and/or nucleocapsid protein among the general population aged [greater than or equal to]6 years was 67.6% (95% CI 66.4% to 68.7%). Seroprevalence increased with age (p < 0.001) and was not different in rural and urban areas (p = 0.822). Compared to unvaccinated adults (62.3%, 95% CI 60.9% to 63.7%), seroprevalence was significantly higher among individuals who had received 1 vaccine dose (81.0%, 95% CI 79.6% to 82.3%, p < 0.001) and 2 vaccine doses (89.8%, 95% CI 88.4% to 91.1%, p < 0.001). The seroprevalence of IgG antibodies among 7,252 HCWs was 85.2% (95% CI 83.5% to 86.7%). Important limitations of the study include the survey design, which was aimed to estimate seroprevalence at the national level and not at a sub-national level, and the non-participation of 19% of eligible individuals in the survey. Conclusions Nearly two-thirds of individuals aged [greater than or equal to]6 years from the general population and 85% of HCWs had antibodies against SARS-CoV-2 by June-July 2021 in India. As one-third of the population is still seronegative, it is necessary to accelerate the coverage of COVID-19 vaccination among adults and continue adherence to non-pharmaceutical interventions., Author(s): Manoj V. Murhekar 1,*, Tarun Bhatnagar 1, Jeromie Wesley Vivian Thangaraj 1, V. Saravanakumar 1, Muthusamy Santhosh Kumar 1, Sriram Selvaraju 2, Kiran Rade 3, C. P. Girish Kumar [...]

Published
2021
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16. Evaluation of ‘TBDetect’ sputum microscopy kit for improved detection of Mycobacterium tuberculosis: a multi-centric validation study

Author

Anthwal, Divya, Gupta, Rakesh Kumar, Gomathi, Narayan Sivaramakrishnan, Tripathy, Srikanth Prasad, Das, Dasarathi, Pati, Sanghamitra, Panwalkar, Nikita, Desikan, Prabha, Bala, Kiran, Singh, Urvashi B., Bhalla, Manpreet, Singhal, Ritu, Verma, Ajoy Kumar, Khayyam, Khalid Umar, Myneedu, Vithal Prasad, Sarin, Rohit, Sharma, Sandeep, Bansal, Avi Kumar, Gupta, Umesh D., Patil, Sripad A., Goyal, Abhinav, Gupta, Ashawant, Singh, Manjula, Gupta, Nalini Kant, Haldar, Sagarika, and Tyagi, Jaya Sivaswami

Published
2021
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24. Baseline Assessments of TB Diagnostic Centers in Selected Public and Private Centers in India and Need for Introducing Quality Management Systems

Author

Singh, Manjula, primary, Ghatbandhe, Pankaj, additional, Mehta, Gaurav, additional, Khatun, Farida, additional, Asad, Seevan, additional, Tyagi, Himshweta, additional, Bansal, Pankaj, additional, Khan, Arbaz, additional, Aamir, Farah Mohammed, additional, Kar, Sonali, additional, Priyadarshini, Pooja, additional, Samal, Pritina, additional, Hanif, Mahmud, additional, Sidiq, Zeeshan, additional, Puri, Shalini, additional, Bhat, Rama, additional, Taley, Ngilang, additional, Sundaray, Sooman, additional, Khan, Md. Abdus Samad, additional, Singh, Ranjan Kumar, additional, Bal, Himadri, additional, Hota, Prasanta Kumar, additional, Mohanty, Paresh Nath, additional, Das, Dasarathi, additional, Chopra, Kamal Kishore, additional, Vashishat, Bhagirath Kumar, additional, Khanna, Ashwani, additional, Chalga, Manjeet Singh, additional, Sachdeva, Kuldeep Singh, additional, Kumar, Nishant, additional, Rao, Raghuram, additional, Joshi, Rajendra P, additional, Yeldandi, Vijay, additional, and Dhawan, Shikha, additional

Published
2022
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25. Impact of cartridge-based nucleic acid amplification test (CBNAAT) introduction on the detection of pulmonary and extra-pulmonary tuberculosis in Bhubaneswar, Odisha

Author

Giri, Sidhartha, primary, Bal, HimadriBhusan, additional, Kar, Sarita, additional, Otta, Sarita, additional, Kumar, Sujeet, additional, Samal, Suryakanta, additional, Pattnaik, Archana, additional, Rout, SunilSwick, additional, Turuk, Jyotirmayee, additional, Das, Dasarathi, additional, and Pati, Sanghamitra, additional

Published
2022
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26. Intensified Pulmonary Tuberculosis Case Finding Among Selected High-Risk Clinical Groups Attending Secondary Level Public Health Care Facilities in Bhubaneswar

Author

Hussain, Tahziba, primary, BARIK, BRAJA SUNDAR, additional, SINGH, KHUSBU, additional, DAS, SHRITAM, additional, CHANDAN, SUDATTA, additional, SWAIN, SUBRAT, additional, DAS, DASARATHI, additional, Pati, Sanghamitra, additional, AGGARWAL, ASHUTOSH, additional, SINGH, MANJULA, additional, and KHAN, A. M., additional

Published
2022
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30. SARS-CoV-2 seroprevalence among the general population and healthcare workers in India, December 2020–January 2021

Author

Murhekar, Manoj V., primary, Bhatnagar, Tarun, additional, Thangaraj, Jeromie Wesley Vivian, additional, Saravanakumar, V., additional, Kumar, Muthusamy Santhosh, additional, Selvaraju, Sriram, additional, Rade, Kiran, additional, Kumar, C.P. Girish, additional, Sabarinathan, R., additional, Turuk, Alka, additional, Asthana, Smita, additional, Balachandar, Rakesh, additional, Bangar, Sampada Dipak, additional, Bansal, Avi Kumar, additional, Chopra, Vishal, additional, Das, Dasarathi, additional, Deb, Alok Kumar, additional, Devi, Kangjam Rekha, additional, Dhikav, Vikas, additional, Dwivedi, Gaurav Raj, additional, Khan, S. Muhammad Salim, additional, Kumar, M. Sunil, additional, Laxmaiah, Avula, additional, Madhukar, Major, additional, Mahapatra, Amarendra, additional, Rangaraju, Chethana, additional, Turuk, Jyotirmayee, additional, Yadav, Rajiv, additional, Andhalkar, Rushikesh, additional, Arunraj, K., additional, Bharadwaj, Dinesh Kumar, additional, Bharti, Pravin, additional, Bhattacharya, Debdutta, additional, Bhat, Jyothi, additional, Chahal, Ashrafjit S., additional, Chakraborty, Debjit, additional, Chaudhury, Anshuman, additional, Deval, Hirawati, additional, Dhatrak, Sarang, additional, Dayal, Rakesh, additional, Elantamilan, D., additional, Giridharan, Prathiksha, additional, Haq, Inaamul, additional, Hudda, Ramesh Kumar, additional, Jagjeevan, Babu, additional, Kalliath, Arshad, additional, Kanungo, Srikanta, additional, Krishnan, Nivethitha N., additional, Kshatri, Jaya Singh, additional, Kumar, Alok, additional, Kumar, Niraj, additional, Kumar, V.G. Vinoth, additional, Lakshmi, G.G.J. Naga, additional, Mehta, Ganesh, additional, Mishra, Nandan Kumar, additional, Mitra, Anindya, additional, Nagbhushanam, K., additional, Nimmathota, Arlappa, additional, Nirmala, A.R., additional, Pandey, Ashok Kumar, additional, Prasad, Ganta Venkata, additional, Qurieshi, Mariya Amin, additional, Reddy, Sirasanambatti Devarajulu, additional, Robinson, Aby, additional, Sahay, Seema, additional, Saxena, Rochak, additional, Sekar, Krithikaa, additional, Shukla, Vijay Kumar, additional, Singh, Hari Bhan, additional, Singh, Prashant Kumar, additional, Singh, Pushpendra, additional, Singh, Rajeev, additional, Srinivasan, Nivetha, additional, Varma, Dantuluri Sheethal, additional, Viramgami, Ankit, additional, Wilson, Vimith Cheruvathoor, additional, Yadav, Surabhi, additional, Yadav, Suresh, additional, Zaman, Kamran, additional, Chakrabarti, Amit, additional, Das, Aparup, additional, Dhaliwal, R.S., additional, Dutta, Shanta, additional, Kant, Rajni, additional, Khan, A.M., additional, Narain, Kanwar, additional, Narasimhaiah, Somashekar, additional, Padmapriyadarshini, Chandrasekaran, additional, Pandey, Krishna, additional, Pati, Sanghamitra, additional, Patil, Shripad, additional, Rajkumar, Hemalatha, additional, Ramarao, Tekumalla, additional, Sharma, Y.K., additional, Singh, Shalini, additional, Panda, Samiran, additional, Reddy, D.C.S., additional, Bhargava, Balram, additional, Anand, Tanu, additional, Babu, Giridhara R., additional, Chauhan, Himanshu, additional, Dikid, Tanzin, additional, Gangakhedkar, Raman R., additional, Kant, Shashi, additional, Kulkarni, Sanket, additional, Muliyil, J.P., additional, Pandey, Ravindra Mohan, additional, Sarkar, Swarup, additional, Shah, Naman, additional, Shrivastava, Aakash, additional, Singh, Sujeet K., additional, Zodpe, Sanjay, additional, Hindupur, Anusha, additional, Asish, P.R., additional, Chellakumar, M., additional, Chokkalingam, D., additional, Dasgupta, Sauvik, additional, Gowtham, M.M.E., additional, Jose, Annamma, additional, Kalaiyarasi, K., additional, Karthik, N.N., additional, Karunakaran, T., additional, Kiruthika, G., additional, Dinesh Kumar, H., additional, Sarath Kumar, S., additional, Sarath Kumar, M.P., additional, Michaelraj, E., additional, Pradhan, Josephine, additional, Arun Prasath, E.B., additional, Gladys Angelin Rachel, D., additional, Rani, Sudha, additional, Rozario, Amanda, additional, Sivakumar, R., additional, Gnana Soundari, P., additional, Sujeetha, K., additional, and Vinod, Arya, additional

Published
2021
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31. SARS-CoV-2 antibody seroprevalence in India, August–September, 2020: findings from the second nationwide household serosurvey

Author

Murhekar, Manoj V, primary, Bhatnagar, Tarun, additional, Selvaraju, Sriram, additional, Saravanakumar, V, additional, Thangaraj, Jeromie Wesley Vivian, additional, Shah, Naman, additional, Kumar, Muthusamy Santhosh, additional, Rade, Kiran, additional, Sabarinathan, R, additional, Asthana, Smita, additional, Balachandar, Rakesh, additional, Bangar, Sampada Dipak, additional, Bansal, Avi Kumar, additional, Bhat, Jyothi, additional, Chopra, Vishal, additional, Das, Dasarathi, additional, Deb, Alok Kumar, additional, Devi, Kangjam Rekha, additional, Dwivedi, Gaurav Raj, additional, Khan, S Muhammad Salim, additional, Kumar, C P Girish, additional, Kumar, M Sunil, additional, Laxmaiah, Avula, additional, Madhukar, Major, additional, Mahapatra, Amarendra, additional, Mohanty, Suman Sundar, additional, Rangaraju, Chethana, additional, Turuk, Alka, additional, Baradwaj, Dinesh Kumar, additional, Chahal, Ashrafjit S, additional, Debnath, Falguni, additional, Haq, Inaamul, additional, Kalliath, Arshad, additional, Kanungo, Srikanta, additional, Kshatri, Jaya Singh, additional, Lakshmi, G G J Naga, additional, Mitra, Anindya, additional, Nirmala, A R, additional, Prasad, Ganta Venkata, additional, Qurieshi, Mariya Amin, additional, Sahay, Seema, additional, Sangwan, Ramesh Kumar, additional, Sekar, Krithikaa, additional, Shukla, Vijay Kumar, additional, Singh, Prashant Kumar, additional, Singh, Pushpendra, additional, Singh, Rajeev, additional, Varma, Dantuluri Sheethal, additional, Viramgami, Ankit, additional, Panda, Samiran, additional, Reddy, D C S, additional, Bhargava, Balram, additional, Andhalkar, Rushikesh, additional, Chaudhury, Anshuman, additional, Deval, Hirawati, additional, Dhatrak, Sarang, additional, Gupta, Rajeev Ranjan, additional, Ilayaperumal, Ezhilarasan, additional, Jagjeevan, Babu, additional, Jha, Ramesh Chandra, additional, Kiran, K, additional, Krishnan, Nivethitha N, additional, Kumar, Alok, additional, Kumar, VG Vinoth, additional, Nagbhushanam, K, additional, Nimmathota, Arlappa, additional, Pandey, Ashok Kumar, additional, Pawar, Harpreet Singh, additional, Rathore, Kushal Singh, additional, Robinson, Aby, additional, Singh, Hari Bhan, additional, Wilson, Vimith Cheruvathoor, additional, Yadav, Ashwini, additional, Yadav, Rajiv, additional, Karunakaran, T, additional, Pradhan, Josephine, additional, Sivakumar, T, additional, Jose, Annamma, additional, Kalaiyarasi, K, additional, Dasgupta, Sauvik, additional, Anusha, R, additional, Anand, Tanu, additional, Babu, Giridhara R, additional, Chauhan, Himanshu, additional, Dikid, Tanzin, additional, Gangakhedkar, Raman R, additional, Kant, Shashi, additional, Kulkarni, Sanket, additional, Muliyil, J P, additional, Pandey, Ravindra Mohan, additional, Sarkar, Swarup, additional, Shrivastava, Aakash, additional, Singh, Sujeet K, additional, Zodpey, Sanjay, additional, Das, Aparup, additional, Das, Pradeep, additional, Dutta, Shanta, additional, Kant, Rajni, additional, Narain, Kanwar, additional, Narasimhaiah, Somashekar, additional, Pati, Sanghamitra, additional, Patil, Shripad, additional, Rajkumar, Hemalatha, additional, Ramarao, Tekumalla, additional, Sarkar, Kamalesh, additional, Singh, Shalini, additional, Toteja, Gurudayal S, additional, and Zaman, Kamran, additional

Published
2021
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32. SARS-CoV-2 Sero-Prevalence among General Population and Healthcare Workers in India, December 2020 - January 2021

Author

Murhekar, Manoj V., primary, Bhatnagar, Tarun, additional, Thangaraj, Jeromie Wesley Vivian, additional, Saravanakumar, V., additional, Kumar, Muthusamy Santhosh, additional, Selvaraju, Sriram, additional, Rade, Kiran, additional, CP, Girish Kumar, additional, Sabarinathan, R., additional, Turuk, Alka, additional, Asthana, Smita, additional, Balachandar, Rakesh, additional, Bangar, Sampada Dipak, additional, Bansal, Avi Kumar, additional, Chopra, Vishal, additional, Das, Dasarathi, additional, Deb, Alok Kumar, additional, Devi, Kangjam Rekha, additional, Dhikav, Vikas, additional, Dwivedi, Gaurav Raj, additional, Khan, S. Muhammad Salim, additional, Kumar, M. Sunil, additional, Laxmaiah, Avula, additional, Madhukar, Major, additional, Mahapatra, Amarendra, additional, Rangaraju, Chethana, additional, Turuk, Jyotirmayee, additional, Yadav, Rajiv, additional, Andhalkar, Rushikesh, additional, Arunraj, K., additional, Baradwaj, Dinesh Kumar, additional, Bharti, Pravin, additional, Bhattacharya, Debdutta, additional, Bhat, Jyothi, additional, Chahal, Ashrafjit S., additional, Chakraborty, Debjit, additional, Chaudhury, Anshuman, additional, Deval, Hirawati, additional, Dhatrak, Sarang, additional, Dayal, Rakesh, additional, Elantamilan, D., additional, Giridharan, Prathiksha, additional, Haq, Inaamul, additional, Hudda, Ramesh Kumar, additional, Jagjeevan, Babu, additional, Kalliath, Arshad, additional, Kanungo, Srikanta, additional, Krishnan, Nivethitha N., additional, Kshatri, Jaya Singh, additional, Kumar, Alok, additional, Kumar, Niraj, additional, Kumar, V.G. Vinoth, additional, Naga Lakshmi, Gangeti Gandhi Jayanthi, additional, Mehta, Ganesh, additional, Mishra, Nandan Kumar, additional, Mitra, Anindya, additional, Nagbhushanam, K., additional, Nimmathota, Arlappa, additional, Nirmala, A.R., additional, Pandey, Ashok Kumar, additional, Prasad, Ganta Venkata, additional, Qurieshi, Mariya Amin, additional, Reddy, Sirasanambatti Devarajulu, additional, Robinson, Aby, additional, Sahay, Seema, additional, Saxena, Rochak, additional, Sekar, Krithikaa, additional, Shukla, Vijay Kumar, additional, Singh, Hari Bhan, additional, Singh, Prashant Kumar, additional, Singh, Pushpendra, additional, Singh, Rajeev, additional, Srinivasan, Nivetha, additional, Varma, Dantuluri Sheethal, additional, Viramgami, Ankit, additional, Wilson, Vimith Cheruvathoor, additional, Yadav, Surabhi, additional, Yadav, Suresh, additional, Zaman, Kamran, additional, Chakrabarti, Amit, additional, Das, Aparup, additional, Dhaliwal, R.S., additional, Dutta, Shanta, additional, Kant, Rajni, additional, Khan, A M, additional, Narain, Kanwar, additional, Narasimhaiah, Somashekar, additional, Padmapriyadarshini, Chandrasekaran, additional, Pandey, Krishna, additional, Pati, Sanghamitra, additional, Patil, Shripad, additional, Rajkumar, Hemalatha, additional, Ramarao, Tekumalla, additional, Sharma, Y.K., additional, Singh, Shalini, additional, Panda, Samiran, additional, Reddy, D.C.S., additional, Bhargava, Balram, additional, and Group, ICMR Serosurveillance, additional

Published
2021
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33. Prevalence of Igg Antibodies Against SARS-CoV-2 Among the General Population and Healthcare Workers in India, June–July 2021

Author

Murhekar, Manoj V., primary, Bhatnagar, Tarun, additional, Thangaraj, Jeromie Wesley Vivian, additional, Saravanakumar, V., additional, Kumar, Muthusamy Santhosh, additional, Selvaraju, Sriram, additional, Rade, Kirankumar, additional, Kumar, C.P. Girish, additional, Sabarinathan, R., additional, Turuk, Alka, additional, Krishnan, Nivethitha N., additional, Robinson, Aby, additional, Srinivasan, Nivetha, additional, Asthana, Smita, additional, Balachandar, Rakesh, additional, Bangar, Sampada Dipak, additional, Bansal, Avi Kumar, additional, Bhat, Jyothi, additional, Chopra, Vishal, additional, Das, Dasarathi, additional, Deb, Alok Kumar, additional, Devi, Kangjam Rekha, additional, Dwivedi, Gaurav Raj, additional, Khan, S. Muhammad Salim, additional, Kumar, M. Sunil, additional, Laxmaiah, Avula, additional, Madhukar, Major, additional, Mahapatra, Amarendra, additional, Rangaraju, Chethana, additional, Turuk, Jyotirmayee, additional, Yadav, Suresh, additional, Anand, P. K., additional, Andhalkar, Rushikesh, additional, Arlappa, Nimmathota, additional, Bashir, Khalid, additional, Baradwaj, Dinesh Kumar, additional, Bharti, Pravin, additional, Bhattacharya, Debdutta, additional, Behera, Sthita Pragnya, additional, Chahal, Ashrafjit S., additional, Chakraborty, Debjit, additional, Chaudhury, Anshuman, additional, Deval, Hirawati, additional, Dhatrak, Sarang, additional, Dhikav, Vikas, additional, Dayal, Rakesh, additional, Giridharan, Prathiksha, additional, Haq, Inaamul, additional, Jagjeevan, Babu, additional, Jain, Agam, additional, Kalliath, Arshad, additional, Kanungo, Srikanta, additional, Karunakaran, T., additional, Kshatri, Jaya Singh, additional, Kumar, Niraj, additional, Kumar, Vijay, additional, Kumar, V.G. Vinod, additional, Naga Lakshmi, Gangeti Gandhi Jayanthi, additional, Mehta, Ganesh, additional, Mitra, Anindya, additional, Nagbhushanam, K., additional, Nirmala, A.R., additional, Palo, Subrat Kumar, additional, Pandey, Ashok Kumar, additional, Prasad, Ganta Venkata, additional, Pucha, Uday Kumar, additional, Qurieshi, Mariya Amin, additional, Sabaharwal, Vikas, additional, Sahay, Seema, additional, Sangwan, Ramesh Kumar, additional, Saxena, Rochak, additional, Sekar, Krithikaa, additional, Shukla, Vijay Kumar, additional, Singh, Hari Bhan, additional, Singh, Prashant Kumar, additional, Singh, Pushpendra, additional, Singh, Rajeev, additional, Thakor, Mahendra, additional, Varma, Dantuluri Sheethal, additional, Viramgami, Ankit, additional, Menon, Pradeep A., additional, Yadav, Rajiv, additional, Yadav, Surabhi, additional, Singh, Manjula, additional, Chakrabarti, Amit, additional, Das, Aparup, additional, Dutta, Shanta, additional, Kant, Rajni, additional, Khan, A.M., additional, Narain, Kanwar, additional, Narasimhaiah, Somashekar, additional, Padmapriyadarshini, Chandrasekaran, additional, Pandey, Krishna, additional, Pati, Sanghamitra, additional, Rajkumar, Hemalatha, additional, Ramesh, T., additional, Sharma, Arun Kumar, additional, Sharma, Y.K., additional, Singh, Shalini, additional, Panda, Samiran, additional, Reddy, D.C.S., additional, and Bhargava, Balram, additional

Published
2021
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35. SARS-CoV-2 Antibody Prevalence in India: Findings from the Second Nationwide Household Serosurvey, August - September 2020

Author

Murhekar, Manoj, primary, Bhatnagar, Tarun, additional, Selvaraju, Sriram, additional, Kumar, V. Saravana, additional, Thangaraj, Jeromie Wesley Vivian, additional, Shah, Naman, additional, Santhosh Kumar, Muthusamy, additional, Rade, Kiran, additional, Sabarinathan, R., additional, Asthana, Smita, additional, Balachandar, Rakesh, additional, Bangar, Sampada Dipak, additional, Bansal, Avi Kumar, additional, Bhat, Jyothi, additional, Chopra, Vishal, additional, Das, Dasarathi, additional, Deb, Alok Kumar, additional, Devi, Kangjam Rekha, additional, Dwivedi, Gaurav Raj, additional, Khan, S. Muhammad Salim, additional, Kumar, CP Girish, additional, Kumar, M. Sunil, additional, Laxmaiah, Avula, additional, Madhukar, Major, additional, Mahapatra, Amarendra, additional, Mohanty, Suman Sundar, additional, Rangaraju, Chethana, additional, Turuk, Alka, additional, Baradwaj, Dinesh Kumar, additional, Chahal, Ashrafjit S., additional, Debnath, Falguni, additional, Haq, Inaamul, additional, Kalliath, Arshad, additional, Kanungo, Srikanta, additional, Kshatri, Jaya, additional, Naga Lakshmi, Gangeti Gandhi Jayanthi, additional, Mitra, Anindya, additional, Nirmala, AR, additional, Prasad, Ganta Venkata, additional, Qurieshi, Mariya Amin, additional, Sahay, Seema, additional, Sangwan, Ramesh Kumar, additional, Sekar, Krithikaa, additional, Shukla, Vijay Kumar, additional, Singh, Prashant Kumar, additional, Singh, Pushpendra, additional, Singh, Rajeev, additional, Varma, Dantuluri Sheethal, additional, Viramgami, Ankit, additional, Panda, Samiran, additional, Reddy, DCS, additional, Bhargava, Balram, additional, and Group, ICMR Serosurveillance, additional

Published
2020
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41. Accuracy of cobas MTB and MTB-RIF/INH for Detection of Mycobacterium tuberculosisand Drug Resistance

Author

de Vos, Margaretha, David, Anura, Duraisamy, Karthickeyan, Nadarajan, Darshaalini, Noroc, Ecaterina, Penn-Nicholson, Adam, Crudu, Valeriu, Giri, Sidhartha, Maurer, Florian P., Pati, Sanghamitra, Stevens, Wendy, Scott, Lesley, Turuk, Jyotimayee, Schumacher, Samuel G., Ruhwald, Morten, Ciobanu, Nelly, Singh Chadha, Sarabijt, Codreanu, Alexandru, Das, Dasarathi, Kahamba, Trish, Kar, Itishree, Macé, Aurélien, Mohanty, Jyoti, Nabeta, Pamela, Kranzer, Katherina, Ongarello, Stefano, Pattanaik, Archana, Romancenco, Elena, Sarin, Sanjay, Singh, Lyndel, Singh, Sunita, and Turcan, Nadia

Abstract

This study evaluated the performance of cobas MTB and cobas MTB-RIF/INH for the diagnosis of tuberculosis (TB) and detection of rifampicin (RIF) and isoniazid (INH) resistance. Adults presenting with pulmonary TB symptoms were recruited in South Africa, Moldova, and India. Performance of cobas MTB was assessed using culture as reference, whereas cobas MTB-RIF/INH was assessed using phenotypic drug susceptibility testing and whole-genome sequencing as composite reference standards. Xpert MTB/RIF (Xpert) or Xpert MTB/RIF Ultra (Ultra) was used as a comparator. The overall sensitivity and specificity of cobas MTB were 95% (95% CI, 93%–96%) and 96% (95% CI, 95%–97%), respectively. Among smear-negative results, the sensitivity of cobas MTB was 75% (95% CI, 66%–83%). Among participants tested with both cobas MTB and Xpert, sensitivity was 96% (95% CI, 94%–97%) for cobas MTB and 95% (95% CI, 93%–97%) for Xpert. Among participants tested with both cobas MTB and Ultra, sensitivity was 88% (95% CI, 81%–92%) for cobas MTB and 89% (95% CI, 83%–93%) for Ultra. Sensitivity and specificity of cobas MTB-RIF/INH for RIF and INH detection were 90% (95% CI, 84%–94%) and 100% (95% CI, 99%–100%), and 89% (95% CI, 84%–93%) and 99.5% (95% CI, 98%–100%), respectively. The cobas MTB and cobas MTB-RIF/INH assays exhibited high performance in a diverse population and present a suitable option for molecular detection of TB and both RIF and INH resistance.

Published
2024
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47. Pattern of InhA and KatG mutations in isoniazid mono resistant Mycobacterium tuberculosisisolates from Odisha

Author

Kumar, Sujeet, Rout, Sunil Swick, Kar, Sarita, Bal, Himadri Bhusan, Turuk, Jyotirmayee, Das, Dasarathi, Hota, Prasanta Kumar, Pati, Sanghamitra, and Giri, Sidhartha

Abstract

We conducted a retrospective analysis of the line probe assay (LPA) data during January to December 2019, from 8 districts of Odisha. The prevalence of Hr-TB (isoniazid resistance only) was 1.53% (50/3272) with a range of 0–3.4% in the 8 districts. Of the 50 Hr-TB strains, katG mutation and inhA mutations were seen in 74% (37/50) and 26% (13/50) strains respectively. S315T1 and C15T were common mutations in katGand inhArespectively. Since these mutations are closely related to high- or low degree resistance to INH, it has therapeutic implications.

Published
2023
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