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Background: This study, therefore, sought to find out factors influencing the utilization of oral HIV Pre-Exposure prophylaxis among Female Sex Workers in Koome Islands. Methodology: Results were obtained using a convenience sampling technique. A target population of 124 respondents was included in the study. A researcher-based questionnaire was designed with relevant questions in line with the study objectives. Data were collected, entered, and analyzed critically using SPSS software. Results: PrEP use among FSWs was at 61.3%, and the level of self-perception as being at risk of contracting HIV infection among FSWs was at 96%. The majority of the FSWs were aware of HIV prevention with oral HIV PrEP. Conclusions: The study shows high self-perception as being at risk of contracting HIV infection among FSWs causing a high need for utilization of PrEP medicines. There is low utilization of PrEP among FSWs with lower levels of education despite their awareness of PrEP medicines. The findings from the study also show that a high proportion of FSWs would not afford PrEP medicines if they were not freely provided by the government and support organizations. The study findings show that the majority of FSWs did not access PrEP medicines because they were out of stock. Recommendations: The government should not only maintain the free provision of oral HIV PrEP medicines but also increase the amount of the medicines supplied to Koome Health Centre III to ensure easy access to and reduce shortages of PrEP medicines. The government should as well ensure a timely supply of PrEP medicines to Koome Health Center III. Healthcare providers should increase the counseling of FSWs before and after initiating them on PrEP medicines.

Background: Viral Load Suppression (VLS) is a product of awareness of a positive HIV diagnosis and adherence to ART. Adolescents on ART should virally suppress within six months of ART to live longer, boost their immune system and reduce chances of transmitting the HIV yet literature shows that adolescents are not virally suppressing as adults. The purpose of this study is to therefore assess the prevalence, associated factors of viral load suppression, and effect of intensified adherence counselling among adolescents on ART at Kisenyi, Kawala, and Kitebi Health Centers Methodology: The study utilized a retrospective chart review design. The study population included individual records of adolescents who had been on ART for at least six months from 1st January 2017 to 31st December 2020. Data were analyzed using both univariate and bivariate analysis to be able to describe the data and establish the associations between independent and dependent Variables. Results: The mean age of the 196 study respondents was 15 (SD 3.4). More than half (53%, N=103) of the respondents were aged 15-19 years while 47% (N=93) were aged between 10-14 years. The prevalence of viral load non-suppression after six months of ART was 36% (n-70), and sixty-nine percent (n-48) of the unsuppressed adolescents were females compared to males (31, n=22). Sixty-nine percent (47) of the unsuppressed adolescents were in primary school while 33% (n=23) of the Anglicans were virally unsuppressed. Recommendations: Health facilities should offer resistance testing to all unsuppressed adolescents before enrolment into the IAC program, IAC should be considered primarily for those adolescents identified to have adherence challenges without resistant mutant strains. Conclusion: it is also evident that not all adolescents who enroll in IAC program benefit from it as shown by the 38% of the adolescents who did not suppress following IAC.