1,031 results on '"Davies, Jamie A."'
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2. The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.
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Alexander, Stephen, Mathie, Alistair, Peters, John, Veale, Emma, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane, Faccenda, Elena, Harding, Simon, Davies, Jamie, Aldrich, Richard, Attali, Bernard, Baggetta, Austin, Becirovic, Elvir, Biel, Martin, Bill, Roslyn, Caceres, Ana, Catterall, William, Conner, Alex, Davies, Paul, De Clerq, Katrien, Delling, Markus, Di Virgilio, Francesco, Falzoni, Simonetta, Fenske, Stefanie, Fortuny-Gomez, Anna, Fountain, Samuel, George, Chandy, Goldstein, Steve, Grimm, Christian, Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Hu, Meiqin, Ijzerman, Ad, Jabba, Sairam, Jarvis, Mike, Jensen, Anders, Jordt, Sven, Kaczmarek, Leonard, Kellenberger, Stephan, Kennedy, Charles, King, Brian, Kitchen, Philip, Liu, Qiang, Lynch, Joseph, Meades, Jessica, Mehlfeld, Verena, Nicke, Annette, Offermanns, Stefan, Perez-Reyes, Edward, Plant, Leigh, Rash, Lachlan, Ren, Dejian, Salman, Mootaz, Sieghart, Werner, Sivilotti, Lucia, Smart, Trevor, Snutch, Terrance, Tian, Jinbin, Trimmer, James, Van den Eynde, Charlotte, Vriens, Joris, Wei, Aguan, Winn, Brenda, Wulff, Heike, Xu, Haoxing, Yang, Fan, Fang, Wei, Yue, Lixia, Zhang, Xiaoli, and Zhu, Michael
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Humans ,Databases ,Pharmaceutical ,Ion Channels ,Ligands ,Receptors ,G-Protein-Coupled ,Databases ,Factual ,Pharmacology - Abstract
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16178. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2023
3. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels
- Author
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Alexander, Stephen Ph, Mathie, Alistair, Peters, John A, Veale, Emma L, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Aldrich, Richard W, Attali, Bernard, Baggetta, Austin M, Becirovic, Elvir, Biel, Martin, Bill, Roslyn M, Catterall, William A, Conner, Alex C, Davies, Paul, Delling, Markus, Virgilio, Francesco Di, Falzoni, Simonetta, Fenske, Stefanie, George, Chandy, Goldstein, Steve AN, Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Jarvis, Mike, Jensen, Anders A, Kaczmarek, Leonard K, Kellenberger, Stephan, Kennedy, Charles, King, Brian, Kitchen, Philip, Lynch, Joseph W, Perez-Reyes, Edward, Plant, Leigh D, Rash, Lachlan, Ren, Dejian, Salman, Mootaz M, Sivilotti, Lucia G, Smart, Trevor G, Snutch, Terrance P, Tian, Jinbin, Trimmer, James S, Van den Eynde, Charlotte, Vriens, Joris, Wei, Aguan D, Winn, Brenda T, Wulff, Heike, Xu, Haoxing, Yue, Lixia, Zhang, Xiaoli, and Zhu, Michael
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Generic health relevance ,Databases ,Pharmaceutical ,Humans ,Ion Channels ,Knowledge Bases ,Ligands ,Pharmacology ,Receptors ,G-Protein-Coupled ,Pharmacology and Pharmaceutical Sciences ,Pharmacology & Pharmacy - Abstract
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15539. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2021
4. Synthetic morphology with agential materials
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Davies, Jamie and Levin, Michael
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- 2023
- Full Text
- View/download PDF
5. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes.
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Alexander, Stephen, Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair, Peters, John, Veale, Emma, Armstrong, Jane, Faccenda, Elena, Harding, Simon, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
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Animals ,Databases ,Pharmaceutical ,Enzyme Inhibitors ,Humans ,Hydrolases ,Isomerases ,Ligands ,Ligases ,Lyases ,Oxidoreductases ,Transferases - Abstract
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14752. Enzymes are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2019
6. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels.
- Author
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Alexander, Stephen, Mathie, Alistair, Peters, John, Veale, Emma, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane, Faccenda, Elena, Harding, Simon, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
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Animals ,Databases ,Pharmaceutical ,Humans ,Ion Channels ,Ligands ,Pharmaceutical Preparations - Abstract
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14749. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2019
7. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes
- Author
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Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Beuve, Annie, Boison, Detlev, Brouckaert, Peter, Burnett, John C, Burns, Kathryn, Dessauer, Carmen, Friebe, Andreas, Garthwaite, John, Gertsch, Jürg, Helsby, Nuala, Izzo, Angelo A, Koesling, Doris, Kuhn, Michaela, Ostrom, Rennolds, Papapetropoulos, Andreas, Potter, Lincoln R, Pyne, Nigel J, Pyne, Susan, Russwurm, Michael, Schmidt, Harald HHW, Seifert, Roland, Stasch, Johannes‐Peter, Szabo, Csaba, van der Stelt, Mario, van der Vliet, Albert, and Watts, Val
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Pharmacology and Pharmaceutical Sciences ,Biomedical and Clinical Sciences ,Generic health relevance ,Animals ,Databases ,Pharmaceutical ,Enzyme Inhibitors ,Humans ,Hydrolases ,Isomerases ,Ligands ,Ligases ,Lyases ,Oxidoreductases ,Transferases ,CGTP Collaborators ,Pharmacology & Pharmacy ,Pharmacology and pharmaceutical sciences - Abstract
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14752. Enzymes are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2019
8. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
- Author
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Alexander, Stephen PH, Mathie, Alistair, Peters, John A, Veale, Emma L, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Aldrich, Richard W, Becirovic, Elvir, Biel, Martin, Catterall, William A, Conner, Alex C, Davies, Paul, Delling, Markus, Di Virgilio, Francesco, Falzoni, Simonetta, George, Chandy, Goldstein, Steve AN, Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Jarvis, Mike, Jensen, Anders A, Kaczmarek, Leonard K, Kellenberger, Stephan, Kennedy, Charles, King, Brian, Lynch, Joseph W, Perez-Reyes, Edward, Plant, Leigh D, Rash, Lachlan D, Ren, Dejian, Sivilotti, Lucia G, Smart, Trevor G, Snutch, Terrance P, Tian, Jinbin, Van den Eynde, Charlotte, Vriens, Joris, Wei, Aguan D, Winn, Brenda T, Wulff, Heike, Xu, Haoxing, Yue, Lixia, Zhang, Xiaoli, and Zhu, Michael
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Generic health relevance ,Animals ,Databases ,Pharmaceutical ,Humans ,Ion Channels ,Ligands ,Pharmaceutical Preparations ,CGTP Collaborators ,Pharmacology and Pharmaceutical Sciences ,Pharmacology & Pharmacy - Abstract
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14749. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
- Published
- 2019
9. Genetically-stable engineered optogenetic gene switches modulate spatial cell morphogenesis in two- and three-dimensional tissue cultures.
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Beyer, Hannes M., Kumar, Sant, Nieke, Marius, Diehl, Carroll M. C., Tang, Kun, Shumka, Sara, Koh, Cha San, Fleck, Christian, Davies, Jamie A., Khammash, Mustafa, and Zurbriggen, Matias D.
- Abstract
Recent advances in tissue engineering have been remarkable, yet the precise control of cellular behavior in 2D and 3D cultures remains challenging. One approach to address this limitation is to genomically engineer optogenetic control of cellular processes into tissues using gene switches that can operate with only a few genomic copies. Here, we implement blue and red light-responsive gene switches to engineer genomically stable two- and three-dimensional mammalian tissue models. Notably, we achieve precise control of cell death and morphogen-directed patterning in 2D and 3D tissues by optogenetically regulating cell necroptosis and synthetic WNT3A signaling at high spatiotemporal resolution. This is accomplished using custom-built patterned LED systems, including digital mirrors and photomasks, as well as laser techniques. These advancements demonstrate the capability of precise spatiotemporal modulation in tissue engineering and open up new avenues for developing programmable 3D tissue and organ models, with significant implications for biomedical research and therapeutic applications. Recent advances in tissue engineering have been remarkable, yet the precise control of cellular behavior in 2D and 3D cultures remains challenging. Here by using light signals, they spatially regulated programmed cell death pathways and cell-cell communication cascades in 2- and 3-dimensional designer tissues. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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10. Production of kidney organoids arranged around single ureteric bud trees, and containing endogenous blood vessels, solely from embryonic stem cells
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Palakkan, Anwar A., Tarnick, Julia, Waterfall, Martin, Sallam, May, Glykofrydis, Fokion, Elhendawi, Mona, and Davies, Jamie A.
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- 2022
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11. Renal engineering: Strategies to address the problem of the ureter
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Davies, Jamie A., Elhendawi, Mona, Palakkan, Anwar A., and Sallam, May
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- 2021
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12. Apocalyptic Topography in Mark’s Gospel: Theophany and Divine Invisibility at Sinai, Horeb, and the Mount of Transfiguration
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Davies, Jamie
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- 2020
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13. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
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Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Fabbro, Doriano, Spedding, Michael, Striessnig, Jörg, Davies, Jamie A, Collaborators, CGTP, Abbracchio, M‐P, Aldrich, R, Al‐Hosaini, K, Arumugam, TV, Attali, B, Bäck, M, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Bettler, B, Biel, M, Birdsall, NJ, Blaho, V, Boison, D, Bräuner‐osborne, H, Bröer, S, Bryant, C, Burnstock, G, Calo, G, Catterall, WA, Ceruti, S, Chan, SL, Chandy, KG, Chazot, P, Chiang, N, Chun, JJ, Chung, J‐J, Clapham, DE, Clapp, L, Connor, MA, Cox, HM, Davies, P, Dawson, PA, Decaen, P, Dent, G, Doherty, P, Douglas, SD, Dubocovich, ML, Fong, TM, Fowler, CJ, Frantz, A, Fuller, P, Fumagalli, M, Futerman, AH, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Goudet, C, Gregory, K, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hamann, J, Hammond, Hancox, JC, Hanson, J, Hanukoglu, I, Hay, DL, Hobbs, AJ, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Irving, AJ, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, MF, Jensen, R, Jockers, R, Kaczmarek, LK, Kanai, Y, Karnik, S, Kellenberger, S, Kemp, S, Kennedy, C, Kerr, ID, Kihara, Y, and Kukkonen, J
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Pharmacology and Pharmaceutical Sciences ,Biomedical and Clinical Sciences ,Generic health relevance ,Databases ,Pharmaceutical ,Humans ,Knowledge Bases ,Ligands ,Proteins ,CGTP Collaborators ,Pharmacology & Pharmacy ,Pharmacology and pharmaceutical sciences - Abstract
The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
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- 2017
14. The many reasons your mileage may vary: Toward a unifying typology of eco-driving behaviors
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Sanguinetti, Angela, Kurani, Ken, and Davies, Jamie
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- 2017
15. Aiming for Outstanding: Action Research from Students of the MSc in the Teaching of Psychology
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Lintern, Fiona, Davies, Jamie, McGinty, Andrew, and Fisher, Jeannine
- Abstract
The first cohort of a new MSc programme is due to complete the course in August 2014. During the three-year online course students conduct several pieces of action research in their classrooms. There is little research specifically related to classroom practice in the pre-tertiary psychology classroom. The following describes the rationale and context of the MSc in the Teaching of Psychology and reports on three students' final year research. The first considers the benefits of Psychology Applied Learning Scenarios (PALS) as applied to an A-level Psychology lesson. This is followed by research on the academic impact the flipped classroom can have on AS and A-level progress and the perceptions of this teaching technique learners have. Finally a plenary designed to develop critical thinking skills and meet the criteria for an "outstanding" lesson is discussed. Conducting action research into one's own teaching produces reflective, self-critical practitioners and these skills are also transmitted to their own students.
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- 2014
16. Kidney organoids: steps towards better organization and function.
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Davies, Jamie A., Holland, Ian, and Gül, Huseyin
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PLURIPOTENT stem cells , *CARDIOVASCULAR system , *DRUG efficacy , *BLOOD flow , *KIDNEY physiology , *KIDNEYS - Abstract
Kidney organoids -- 3D representations of kidneys made either from pluripotent or tissue stem cells -- have been available for well over a decade. Their application could confer notable benefits over longstanding in vivo approaches with the potential for clinically aligned human cells and reduced ethical burdens. They been used, at a proof-of-concept level, in development in disease modeling (including with patient-derived stem cells), and in screening drugs for efficacy/toxicity. They differ from real kidneys: they represent only foetal-stage tissue, in their simplest forms they lack organ-scale anatomical organization, they lack a properly arranged vascular system, and include non-renal cells. Cell specificity may be improved by better techniques for differentiation and/or sorting. Sequential assembly techniques that mimic the sequence of natural development, and localized sources of differentiation-inducing signals, improve organ-scale anatomy. Organotypic vascularization remains a challenge: capillaries are easy, but the large vessels that should serve them are absent from organoids and, even in cultured real kidneys, these large vessels do not survive without blood flow. Transplantation of organoids into hosts results in their being vascularized (though probably not organotypically) and in some renal function. It will be important to transplant more advanced organoids, with a urine exit, in the near future to assess function more stringently. Transplantation of human foetal kidneys, followed by nephrectomy of host kidneys, keeps rats alive for many weeks, raising hope that, if organoids can be produced even to the limited size and complexity of foetal kidneys, they may one day be useful in renal replacement. [ABSTRACT FROM AUTHOR]
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- 2024
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17. 1. Human physiology
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Davies, Jamie A., primary
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- 2021
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18. 2. Energy
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Davies, Jamie A., primary
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- 2021
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19. Concluding remarks
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Davies, Jamie A., primary
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- 2021
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20. 5. Reacting and thinking
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Davies, Jamie A., primary
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- 2021
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21. Human Physiology: A Very Short Introduction
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Davies, Jamie A., primary
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- 2021
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22. 7. Defence
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Davies, Jamie A., primary
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- 2021
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23. 4. Sensation
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Davies, Jamie A., primary
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- 2021
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24. 6. From thought to action
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Davies, Jamie A., primary
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- 2021
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25. 8. Reproduction
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Davies, Jamie A., primary
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- 2021
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26. 3. Homeostasis
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Davies, Jamie A., primary
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- 2021
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27. Sampling, extraction and incidence of redberry mites (Acalitus essigi) on blackberries in Australia
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Law, Hui Meng, Allen, Geoff R., Davies, Jamie T., Corkrey, Ross, Buntain, Michele, and Quarrell, Stephen R.
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- 2020
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28. The Concise Guide to PHARMACOLOGY 2015/16: Enzymes.
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Alexander, Stephen, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil, Peters, John, Benson, Helen, Faccenda, Elena, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
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Animals ,Databases ,Pharmaceutical ,Enzymes ,Humans ,Ligands - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13354/full. G protein-coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
29. The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors.
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Alexander, Stephen, Cidlowski, John, Kelly, Eamonn, Marrion, Neil, Peters, John, Benson, Helen, Faccenda, Elena, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
- Subjects
Animals ,Databases ,Pharmaceutical ,Humans ,Ligands ,Receptors ,Cytoplasmic and Nuclear - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13352/full. Nuclear hormone receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
30. The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
- Author
-
Alexander, Stephen, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil, Peters, John, Benson, Helen, Faccenda, Elena, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
- Subjects
Animals ,Databases ,Pharmaceutical ,Humans ,Ligands ,Receptors ,Cell Surface - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13353/full. G protein-coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
31. The Concise Guide to PHARMACOLOGY 2015/16: Transporters.
- Author
-
Alexander, Stephen, Kelly, Eamonn, Marrion, Neil, Peters, John, Benson, Helen, Faccenda, Elena, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
- Subjects
Animals ,Databases ,Pharmaceutical ,Humans ,Ligands ,Membrane Transport Proteins - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13355/full. G protein-coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
32. The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels.
- Author
-
Alexander, Stephen, Kelly, Eamonn, Marrion, Neil, Peters, John, Benson, Helen, Faccenda, Elena, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
- Subjects
Animals ,Databases ,Pharmaceutical ,Humans ,Ion Channels ,Ligands - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13351/full. Other ion channels are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
33. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors.
- Author
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Alexander, Stephen, Davenport, Anthony, Kelly, Eamonn, Marrion, Neil, Peters, John, Benson, Helen, Faccenda, Elena, Pawson, Adam, Sharman, Joanna, Southan, Christopher, and Davies, Jamie
- Subjects
Animals ,Databases ,Pharmaceutical ,Humans ,Ligands ,Receptors ,G-Protein-Coupled - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13348/full. G protein-coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
34. The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels
- Author
-
Alexander, Stephen PH, Catterall, William A, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, and Collaborators, CGTP
- Subjects
Pharmacology and Pharmaceutical Sciences ,Biomedical and Clinical Sciences ,1.1 Normal biological development and functioning ,Underpinning research ,Generic health relevance ,Animals ,Databases ,Pharmaceutical ,Humans ,Ligands ,Potassium Channels ,Voltage-Gated ,Voltage-Gated Sodium Channels ,CGTP Collaborators ,Pharmacology & Pharmacy ,Pharmacology and pharmaceutical sciences - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13350/full. Voltage-gated ion channels are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
35. The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels
- Author
-
Alexander, Stephen PH, Peters, John A, Kelly, Eamonn, Marrion, Neil, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, and Collaborators, CGTP
- Subjects
Pharmacology and Pharmaceutical Sciences ,Biomedical and Clinical Sciences ,1.1 Normal biological development and functioning ,Underpinning research ,Generic health relevance ,Animals ,Databases ,Pharmaceutical ,Humans ,Ligand-Gated Ion Channels ,Ligands ,CGTP Collaborators ,Pharmacology & Pharmacy ,Pharmacology and pharmaceutical sciences - Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13349/full. Ligand-gated ion channels are one of the eight major pharmacological targets into which the Guide is divided, with the others being: ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
- Published
- 2015
36. Inverse pharmacology: Approaches and tools for introducing druggability into engineered proteins
- Author
-
Davies, Jamie A., Ireland, Sam, Harding, Simon, Sharman, Joanna L., Southan, Christopher, and Dominguez-Monedero, Alazne
- Published
- 2019
- Full Text
- View/download PDF
37. Chapter 15 - The urinary system
- Author
-
Davies, Jamie A.
- Published
- 2025
- Full Text
- View/download PDF
38. How Assumptions About Consumers Influence Estimates of Electric Vehicle Miles Traveled of Plug-in Hybrid Electric Vehicles: A Review of PHEV Use Data and Possible Implications for the SAEJ2841 Utility Factor (UF) Standard
- Author
-
Davies, Jamie
- Abstract
To characterize the environmental impact and petroleum displacement potential of Plug-in Hybrid Electric Vehicles (PHEVs) it is necessary to know what fraction of travel occurs in each of the two energy use modes. Currently, the Society of Automotive Engineers (SAE) estimates the fraction of US travel a PHEV with a given Charge Depleting (CD) range will electrify based on travel data from a national, single drivingday diary and the assumption that PHEVs are charged onceper day. This estimate is used by policy makers, transportation researchers and automotive engineers for purposes which range from State Policy (California Zero Emission Vehicle (ZEV) Mandate), battery lifetime estimates, vehicle to grid interactions and other analyses. However, the SAEJ2841 standard is most realistic for instances where its assumptions are valid ; i.e. consumers do not base their PHEV purchase decision on their driving needs, charge once per day at home, don’t have access to or use public charging infrastructure, and drive their PHEV similarly to the vehicle it replaced. This combination of assumptions is only a single use case for PHEVs and represents untested, universal assumptions about how consumers will choose to purchase, drive and recharge PHEVs. We investigate these four assumptions made in the SAE J2841 standard, and compare each one against the best publically available consumer demonstration and academic analyses to begin the process of assessing assumptions and understanding potential implications for analyses or policies which currently use the SAE J2841. Overall, this analysis is meant to bring depth to the discussion of PHEV impacts and policy which seeks to incentivize electric driving.
- Published
- 2014
39. The Concise Guide to PHARMACOLOGY 2023/24: Ion channels
- Author
-
Alexander, Stephen P. H., primary, Mathie, Alistair A., additional, Peters, John A., additional, Veale, Emma L., additional, Striessnig, Jörg, additional, Kelly, Eamonn, additional, Armstrong, Jane F., additional, Faccenda, Elena, additional, Harding, Simon D., additional, Davies, Jamie A., additional, Aldrich, Richard W., additional, Attali, Bernard, additional, Baggetta, Austin M., additional, Becirovic, Elvir, additional, Biel, Martin, additional, Bill, Roslyn M., additional, Caceres, Ana I., additional, Catterall, William A., additional, Conner, Alex C., additional, Davies, Paul, additional, De Clerq, Katrien, additional, Delling, Markus, additional, Di Virgilio, Francesco, additional, Falzoni, Simonetta, additional, Fenske, Stefanie, additional, Fortuny‐Gomez, Anna, additional, Fountain, Samuel, additional, George, Chandy, additional, Goldstein, Steve A. N., additional, Grimm, Christian, additional, Grissmer, Stephan, additional, Ha, Kotdaji, additional, Hammelmann, Verena, additional, Hanukoglu, Israel, additional, Hu, Meiqin, additional, Ijzerman, Ad P., additional, Jabba, Sairam V., additional, Jarvis, Mike, additional, Jensen, Anders A., additional, Jordt, Sven E., additional, Kaczmarek, Leonard K., additional, Kellenberger, Stephan, additional, Kennedy, Charles, additional, King, Brian, additional, Kitchen, Philip, additional, Liu, Qiang, additional, Lynch, Joseph W., additional, Meades, Jessica, additional, Mehlfeld, Verena, additional, Nicke, Annette, additional, Offermanns, Stefan, additional, Perez‐Reyes, Edward, additional, Plant, Leigh D., additional, Rash, Lachlan, additional, Ren, Dejian, additional, Salman, Mootaz M., additional, Sieghart, Werner, additional, Sivilotti, Lucia G., additional, Smart, Trevor G., additional, Snutch, Terrance P., additional, Tian, Jinbin, additional, Trimmer, James S., additional, Van den Eynde, Charlotte, additional, Vriens, Joris, additional, Wei, Aguan D., additional, Winn, Brenda T., additional, Wulff, Heike, additional, Xu, Haoxing, additional, Yang, Fan, additional, Fang, Wei, additional, Yue, Lixia, additional, Zhang, Xiaoli, additional, and Zhu, Michael, additional
- Published
- 2023
- Full Text
- View/download PDF
40. The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets
- Author
-
Alexander, Stephen P. H., primary, Kelly, Eamonn, additional, Mathie, Alistair A., additional, Peters, John A., additional, Veale, Emma L., additional, Armstrong, Jane F., additional, Buneman, O. Peter, additional, Faccenda, Elena, additional, Harding, Simon D., additional, Spedding, Michael, additional, Cidlowski, John A., additional, Fabbro, Doriano, additional, Davenport, Anthony P., additional, Striessnig, Jörg, additional, Davies, Jamie A., additional, Ahlers‐Dannen, Katelin E., additional, Alqinyah, Mohammed, additional, Arumugam, Thiruma V., additional, Bodle, Christopher, additional, Dagner, Josephine Buo, additional, Chakravarti, Bandana, additional, Choudhuri, Shreoshi P., additional, Druey, Kirk M., additional, Fisher, Rory A., additional, Gerber, Kyle J., additional, Hepler, John R., additional, Hooks, Shelley B., additional, Kantheti, Havish S., additional, Karaj, Behirda, additional, Layeghi‐Ghalehsoukhteh, Somayeh, additional, Lee, Jae‐Kyung, additional, Luo, Zili, additional, Martemyanov, Kirill, additional, Mascarenhas, Luke D., additional, McNabb, Harrison, additional, Montañez‐Miranda, Carolina, additional, Ogujiofor, Osita, additional, Phan, Hoa, additional, Roman, David L., additional, Shaw, Vincent, additional, Sjogren, Benita, additional, Sobey, Christopher, additional, Spicer, Mackenzie M., additional, Squires, Katherine E., additional, Sutton, Laurie, additional, Wendimu, Menbere, additional, Wilkie, Thomas, additional, Xie, Keqiang, additional, Zhang, Qian, additional, and Zolghadri, Yalda, additional
- Published
- 2023
- Full Text
- View/download PDF
41. Optogenetic Downregulation of Protein Levels to Control Programmed Cell Death in Mammalian Cells with a Dual Blue-Light Switch
- Author
-
Fischbach, Patrick, primary, Gonschorek, Patrick, additional, Baaske, Julia, additional, Davies, Jamie A., additional, Weber, Wilfried, additional, and Zurbriggen, Matias D., additional
- Published
- 2020
- Full Text
- View/download PDF
42. Symbolism, signs, and accounts of electric vehicles in California
- Author
-
Kurani, Kenneth S., Caperello, Nicolette, TyreeHageman, Jennifer, and Davies, Jamie
- Published
- 2018
- Full Text
- View/download PDF
43. Variation in Charging of Privately-Held PEVs: Implications for Analysis, Markets, and Policy
- Author
-
Davies, Jamie and Kurani, Kenneth S
- Abstract
As the markets for plug-in electric vehicles (PEVs) and the deployment of electricity infrastructure to charge them are in an initial, dynamic launch phase, there is an absence of stable data on PEV purchase and charging behavior. How then are social, economic, and environmental effects of PEVs being estimated? How are plans for PEV and electric vehicle service equipment (EVSE) production made? How are the effective means to manage that behavior anticipated? In the absence of data, analysts make assumptions. These are often simple assumptions, or perhaps simplifying assumptions. In this chapter we compare PEV charging assumptions to real world measures and assess the implications of changing these assumptions for analysis, markets and policy.
- Published
- 2013
44. Households’ Plug-in Hybrid Electric Vehicle Recharging Behavior: Observed variation in households’ use of a 5kWh blended PHEV-conversion
- Author
-
Davies, Jamie and Kurani, Kenneth S.
- Abstract
Plug-in hybrid electric vehicles (PHEVs), which run on both electricity from the grid and gasoline, are touted as providing some of the societal and environmental benefits of electric vehicles for a large portion of motorists’ daily travel, while also acting as a transitional technology toward fully electric vehicles. To test analysts’ assumptions about how PHEV users will recharge their vehicles, the observed recharging behaviors of forty households that participated in a PHEV demonstration in Northern California are reported. Recharging behavior is summarized across all households’ last week of their four-week PHEV trial period with regards to the time-of-day, frequency of plugging-in, and electricity demand to recharge the vehicles. While the means of the frequency distribution of plug-in events among demonstration households is similar to prior recharging assumptions made by analysts, the distributions are not symmetrical about the mean and there exists a large variation in both the average number of times households plugged-in per day and the average energy per plug-in event. Further, there is no strong correspondence between the number of daily plug-in events and total daily electricity demand. The range of behaviors reported here support the contention that the success of PHEVs in meeting energy and emissions goals relies on PHEV users’ recharging and driving behavior as much or more as on PHEV designs.
- Published
- 2010
45. Learning from Consumers: Plug-In Hybrid Electric Vehicle (PHEV) Demonstration and Consumer Education, Outreach, and Market Research Program
- Author
-
Kurani, Kenneth S, Axsen, Jonn, Caperello, Nicolette, Davies, Jamie, and Stillwater, Tai
- Subjects
UCD-ITS-RR-09-21 - Abstract
Will people recharge a vehicle that does not have to be recharged? This, and the degree to which plug-in hybrid electric vehicle (PHEV) designs emphasize gasoline or electricity, are central to assessing the energy and environmental effects of PHEVs. Plug-in conversions of hybrid vehicles are being made available to (predominately new-car buying) households throughout the Sacramento region for four to six weeks each. The vehicles are instrumented to report travel and energy; households are interviewed and surveyed. Results from the first 34 households—all selected in part because they can recharge a vehicle at home—indicate that on average they will recharge a PHEV about once per day, but with wide variation across households. The PHEV designs created by these households emphasize increased fuel economy rather than all-electric operation—as did the designs of prior representative samples of new-car buyers (who had not driven PHEVs). This result may be due in part to 1) “anchoring” (respondents are driving a PHEV that does not practically allow all-electric operation), and 2) households not creating integrated assessments of gasoline and electricity use/cost from the in-vehicle and internet-based instrumentation. Over the PHEV trials, narratives are co-authored about the PHEVs and their place in the ongoing life-stories of the participants. The primary themes to emerge are changing driving behavior, recharging habits and etiquette, confusion about PHEVs and how they work, and the role of payback analyses and more intuitive assessments of whether PHEVs are “worth it.” Tracing social interactions by the participants about the PHEVs reveals that complex translation of ideas and information about PHEVs is occurring as the PHEV drivers, in particular, use their trial period to reflexively explore lifestyle and identity possibilities of these new vehicles.
- Published
- 2009
46. Stratified tissue biofabrication by rotational internal flow layer engineering
- Author
-
Holland, Ian, primary, Shu, Wenmiao, additional, and Davies, Jamie A, additional
- Published
- 2023
- Full Text
- View/download PDF
47. The IUPHAR/BPS Guide to PHARMACOLOGY in 2024.
- Author
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Harding, Simon D, Armstrong, Jane F, Faccenda, Elena, Southan, Christopher, Alexander, Stephen P H, Davenport, Anthony P, Spedding, Michael, and Davies, Jamie A
- Published
- 2024
- Full Text
- View/download PDF
48. Mammalian Synthetic Biology as a Research Tool
- Author
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Davies, Jamie A., primary
- Published
- 2019
- Full Text
- View/download PDF
49. Special Features of Mammalian Systems
- Author
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Davies, Jamie A., primary
- Published
- 2019
- Full Text
- View/download PDF
50. An Introduction to Mammalian Synthetic Biology
- Author
-
Davies, Jamie A., primary
- Published
- 2019
- Full Text
- View/download PDF
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