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8,085 results on '"Davis, Thomas"'

6. Benchmarking Conventional and Learned Video Codecs with a Low-Delay Configuration

Author

Teng, Siyue, Jiang, Yuxuan, Gao, Ge, Zhang, Fan, Davis, Thomas, Liu, Zoe, and Bull, David

Subjects
Computer Science - Multimedia, Computer Science - Computer Vision and Pattern Recognition, Electrical Engineering and Systems Science - Image and Video Processing
Abstract

Recent advances in video compression have seen significant coding performance improvements with the development of new standards and learning-based video codecs. However, most of these works focus on application scenarios that allow a certain amount of system delay (e.g., Random Access mode in MPEG codecs), which is not always acceptable for live delivery. This paper conducts a comparative study of state-of-the-art conventional and learned video coding methods based on a low delay configuration. Specifically, this study includes two MPEG standard codecs (H.266/VVC VTM and JVET ECM), two AOM codecs (AV1 libaom and AVM), and two recent neural video coding models (DCVC-DC and DCVC-FM). To allow a fair and meaningful comparison, the evaluation was performed on test sequences defined in the AOM and MPEG common test conditions in the YCbCr 4:2:0 color space. The evaluation results show that the JVET ECM codecs offer the best overall coding performance among all codecs tested, with a 16.1% (based on PSNR) average BD-rate saving over AOM AVM, and 11.0% over DCVC-FM. We also observed inconsistent performance with the learned video codecs, DCVC-DC and DCVC-FM, for test content with large background motions.

Published
2024

12. Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients With Pneumonia: A Prospective Observational Study.

Author

Bergin, Stephen, Chemaly, Roy, Dadwal, Sanjeet, Hill, Joshua, Lee, Yeon, Haidar, Ghady, Luk, Alfred, Drelick, Alexander, Chin-Hong, Peter, Benamu, Esther, Khawaja, Fareed, Nanayakkara, Deepa, Papanicolaou, Genovefa, Small, Catherine, Barron, Michelle, Davis, Thomas, McClain, Micah, Maziarz, Eileen, Madut, Deng, Bedoya, Armando, Gilstrap, Daniel, Todd, Jamie, Barkauskas, Christina, Bigelow, Robert, Leimberger, Jeffrey, Tsalik, Ephraim, Wolf, Olivia, Mughar, Mona, Hollemon, Desiree, Duttagupta, Radha, Lupu, Daniel, Bercovici, Sivan, Perkins, Bradley, Blauwkamp, Timothy, Fowler, Vance, Holland, Thomas, and Fung, Monica

Subjects
bronchoscopy, hematologic malignancy, hematopoietic cell transplant, immunocompromised pneumonia, microbial cell-free DNA sequencing, Adult, Humans, Prospective Studies, Pneumonia, Sequence Analysis, DNA, Immunocompromised Host
Abstract

BACKGROUND: Pneumonia is a common cause of morbidity and mortality, yet a causative pathogen is identified in a minority of cases. Plasma microbial cell-free DNA sequencing may improve diagnostic yield in immunocompromised patients with pneumonia. METHODS: In this prospective, multicenter, observational study of immunocompromised adults undergoing bronchoscopy to establish a pneumonia etiology, plasma microbial cell-free DNA sequencing was compared to standardized usual care testing. Pneumonia etiology was adjudicated by a blinded independent committee. The primary outcome, additive diagnostic value, was assessed in the Per Protocol population (patients with complete testing results and no major protocol deviations) and defined as the percent of patients with an etiology of pneumonia exclusively identified by plasma microbial cell-free DNA sequencing. Clinical additive diagnostic value was assessed in the Per Protocol subgroup with negative usual care testing. RESULTS: Of 257 patients, 173 met Per Protocol criteria. A pneumonia etiology was identified by usual care in 52/173 (30.1%), plasma microbial cell-free DNA sequencing in 49/173 (28.3%) and the combination of both in 73/173 (42.2%) patients. Plasma microbial cell-free DNA sequencing exclusively identified an etiology of pneumonia in 21/173 patients (additive diagnostic value 12.1%, 95% confidence interval [CI], 7.7% to 18.0%, P < .001). In the Per Protocol subgroup with negative usual care testing, plasma microbial cell-free DNA sequencing identified a pneumonia etiology in 21/121 patients (clinical additive diagnostic value 17.4%, 95% CI, 11.1% to 25.3%). CONCLUSIONS: Non-invasive plasma microbial cell-free DNA sequencing significantly increased diagnostic yield in immunocompromised patients with pneumonia undergoing bronchoscopy and extensive microbiologic and molecular testing. CLINICAL TRIALS REGISTRATION: NCT04047719.

Published
2024

17. The influence of microbial colonization on inflammatory versus pro-healing trajectories in combat extremity wounds

Author

Schobel, Seth A., Gann, Eric R., Unselt, Desiree, Grey, Scott F., Lisboa, Felipe A., Upadhyay, Meenu M., Rouse, Michael, Tallowin, Simon, Be, Nicholas A., Zhang, Xijun, Dalgard, Clifton L., Wilkerson, Matthew D., Hauskrecht, Milos, Badylak, Stephen F., Zamora, Ruben, Vodovotz, Yoram, Potter, Benjamin K., Davis, Thomas A., and Elster, Eric A.

Published
2024
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25. Cerebral Palsy

Author

Davis, Thomas W., Tolentino, Jonathan, Lee, Stephanie M. J., Zaw, Catherine, Talente, Gregg, Kuo, Alice A, editor, Pilapil, Mariecel, editor, DeLaet, David E., editor, Peacock, Cynthia, editor, and Sharma, Niraj, editor

Published
2024
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26. Towards a Data Provenance Collection and Visualization Framework for Monitoring and Analyzing HPC Environments

Author

Sukhija, Nitin, Bautista, Elizabeth, Schultz, Adam, Whitney, Cary, Davis, Thomas, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Chbeir, Richard, editor, Benslimane, Djamal, editor, Zervakis, Michalis, editor, Manolopoulos, Yannis, editor, Ngyuen, Ngoc Thanh, editor, and Tekli, Joe, editor

Published
2024
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30. Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Author

Aguado, Julio, Amarilla, Alberto A., Taherian Fard, Atefeh, Albornoz, Eduardo A., Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K., Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A., Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E., Parry, Rhys, Sng, Julian D. J., Isaacs, Ariel, Khromykh, Alexander A., Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P., Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N., Woodruff, Trent M., Mar, Jessica C., Watterson, Daniel, and Wolvetang, Ernst J.

Published
2023
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31. The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity

Author

Baumgartner, Christina K., Ebrahimi-Nik, Hakimeh, Iracheta-Vellve, Arvin, Hamel, Keith M., Olander, Kira E., Davis, Thomas G. R., McGuire, Kathleen A., Halvorsen, Geoff T., Avila, Omar I., Patel, Chirag H., Kim, Sarah Y., Kammula, Ashwin V., Muscato, Audrey J., Halliwill, Kyle, Geda, Prasanthi, Klinge, Kelly L., Xiong, Zhaoming, Duggan, Ryan, Mu, Liang, Yeary, Mitchell D., Patti, James C., Balon, Tyler M., Mathew, Rebecca, Backus, Carey, Kennedy, Domenick E., Chen, Angeline, Longenecker, Kenton, Klahn, Joseph T., Hrusch, Cara L., Krishnan, Navasona, Hutchins, Charles W., Dunning, Jax P., Bulic, Marinka, Tiwari, Payal, Colvin, Kayla J., Chuong, Cun Lan, Kohnle, Ian C., Rees, Matthew G., Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A., Wu, Meng-Ju, Suermondt, Juliette S. M. T., Knudsen, Nelson H., Cheruiyot, Collins K., Sen, Debattama R., Griffin, Gabriel K., Golub, Todd R., El-Bardeesy, Nabeel, Decker, Joshua H., Yang, Yi, Guffroy, Magali, Fossey, Stacey, Trusk, Patricia, Sun, Im-Meng, Liu, Yue, Qiu, Wei, Sun, Qi, Paddock, Marcia N., Farney, Elliot P., Matulenko, Mark A., Beauregard, Clay, Frost, Jennifer M., Yates, Kathleen B., Kym, Philip R., and Manguso, Robert T.

Published
2023
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35. Spatial transformations in entrepreneurship : a study of the Liverpool 'Baltic Triangle'

Author

Davis, Thomas

Abstract

Entrepreneurship is frequently seen as a transformational force for underdeveloped urban spaces. While much research has emphasized the role of urban governance or visionary individuals, less is known about how entrepreneurship works with and on these spaces over time. Investigating these processes involves taking entrepreneurship out of primarily economic concerns, and into a debate on the social, material and historical constitution of built environments. In this thesis I present a study of the Liverpool Baltic Triangle, exploring how the past is brought into its present-day entrepreneurial transformations. The main body of my dissertation is compiled of four main chapters which form standalone paper-based contributions but also fit together here as a cohesive study (along with an introduction which is presented in Chapter One and a discussion and conclusion presented in Chapter Six). Within this work, I present two analytical studies, both taking on a key thinker on space which I theoretically set in relation to entrepreneurial activity at the Baltic Triangle. I begin with a literature review, presented in Chapter Two, where I identify and interrogate theoretical and analytical approaches that have been employed for studying urban spaces and entrepreneurship. I present a typology of this body of work that is comprised of four distinct categories, including a sub-set of approaches that have explored the historical character of the 'in-between' and 'lived' aspects of urban entrepreneurial spaces, I subsequently use these latter studies as a springboard for my own research. In Chapter Three, I outline a methodological agenda for my empirical research. I introduce Henri Lefebvre's 'spatial triad' and elaborate a set of methodological principles and processes for mobilizing his triadic notion of space for studying entrepreneurship. I emphasize historicized methodological procedures incorporated into a research design that combines multiple analytical techniques. My first empirical study, which I present in Chapter Four, analyzes the entrepreneurial transformation of the Baltic Triangle as a history of spatial change. Informed by the methodological agenda I outline above I operationalize Henri Lefebvre's theory of space, reading his work alongside Spinosa, Flores and Dreyfus's theory of entrepreneurial 'world-making,' to generate a dynamic account of the Baltic Triangle as a contested site of openings and restrictions for entrepreneurship. I use Lefebvre's triadic spatial elements as a configuring frame for witnessing how entrepreneurial practices continually emerge 'in-between' (and subsequently transform) the Baltics' spatial characteristics through time. My second empirical study, which I present in Chapter Five, explores the entrepreneurial renewal of one of the Baltic Triangle's flagship buildings: the Cain's brewery complex. Here, I focus on the transformational potential of aesthetic encounters with space, drawing inspiration from Walter Benjamin's kaleidoscopic account of his memories of childhood recalled through his present-day experience of the streets of Berlin, to investigate how the history of the Cain's brewery is experienced by entrepreneurial individuals as acts of remembrance. Employing conceptual and analytical techniques derived from a close reading of Benjamin's A Berlin Chronicle, I emphasize a cyclical process with a transformational potential: how entrepreneurial subjects remember is formed in encounters with the brewery; architectural experiences contributing to the collective articulation of a new entrepreneurial form. By employing Lefebvre's spatial theory in Chapter Four I investigate the origins of entrepreneurial beginnings and how they grow and develop, using his triadic elements to trace the creative acts of multiple people as they collectively bring new ideas into commerce and contribute to the remaking of the Baltic Triangle. Conversant with Lefebvre, I emphasize especially the unfinished nature of this process. Entrepreneurial remaking creates new spatial conditions that eventually lead to an 'un-making' as the space becomes increasingly commercial, requiring new formulations of entrepreneurial action. Through my reading of Benjamin's work on remembrance in Chapter Five, I emphasize a different process of entrepreneurial renewal. Benjamin' writings on memory offers a more aesthetic sensibility - he is interested less in the broader movements of change as they unfold through time, and more at how history is experienced in the present moment through personal encounters with architecture. Through Benjamin, I am able to get in closer to what it means to creatively inhabit the Cain's brewery to offer new insights into how its resident entrepreneurs pick up on its latent potential. By engaging these two spatial theorists in my study of the Baltic Triangle, my study reveals entrepreneurship as both more and less than frequently assumed. More, in the sense of its pivotal role in the facilitation of transitions between social, material, cultural or historical moments in space, and thus, downgrading the role of primarily economic concerns with urban governance. But also, less, in terms of the role that any single entrepreneurial individual can play in creating such epochal spatial transformations.

Published
2022
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36. ''Harlem's First Congressman' and 'Negro News', 1933-1944'

Author

Davis, Thomas. J.

Subjects
United States. Congress -- History -- Demographic aspects -- Media coverage, New York -- History -- Political aspects -- Demographic aspects, African American legislators -- Elections -- Media coverage -- 1940s (Decade) AD -- 1930s (Decade) AD, Press and politics -- History -- Demographic aspects -- 1940s (Decade) AD -- 1930s (Decade) AD, Legislators -- Elections -- Media coverage, Ethnic, cultural, racial issues/studies, History
Abstract

On Tuesday, 7 November 1944, Harlem voters elected the Rev. Adam Clayton Powell Jr. to be New York's first black congressman. The 36-year-old joined Chicago's William Levi Dawson in January [...]

Published
2023

37. In operando NMR investigations of the aqueous electrolyte chemistry during electrolytic CO2 reduction

Author

Sven Jovanovic, Peter Jakes, Steffen Merz, Davis Thomas Daniel, Rüdiger-A. Eichel, and Josef Granwehr

Subjects
Chemistry, QD1-999
Abstract

Abstract The electrolytic reduction of CO2 in aqueous media promises a pathway for the utilization of the green house gas by converting it to base chemicals or building blocks thereof. However, the technology is currently not economically feasible, where one reason lies in insufficient reaction rates and selectivities. Current research of CO2 electrolysis is becoming aware of the importance of the local environment and reactions at the electrodes and their proximity, which can be only assessed under true catalytic conditions, i.e. by in operando techniques. In this work, multinuclear in operando NMR techniques were applied in order to investigate the evolution of the electrolyte chemistry during CO2 electrolysis. The CO2 electroreduction was performed in aqueous NaHCO3 or KHCO3 electrolytes at silver electrodes. Based on 13C and 23Na NMR studies at different magnetic fields, it was found that the dynamic equilibrium of the electrolyte salt in solution, existing as ion pairs and free ions, decelerates with increasingly negative potential. In turn, this equilibrium affects the resupply rate of CO2 to the electrolysis reaction from the electrolyte. Substantiated by relaxation measurements, a mechanism was proposed where stable ion pairs in solution catalyze the bicarbonate dehydration reaction, which may provide a new pathway for improving educt resupply during CO2 electrolysis.

Published
2023
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43. Previous immune checkpoint inhibitor therapy is associated with decreased COVID-19-related hospitalizations and complications in patients with cancer: Results of a propensity-matched analysis of the OnCovid registry

Author

Mostaghim, Anahita, Minkove, Samuel, Aguilar-Company, Juan, Ruiz-Camps, Isabel, Eremiev-Eremiev, Simeon, Dettorre, Gino M., Fox, Laura, Tondini, Carlo, Brunet, Joan, Carmona-García, MCarmen, Lambertini, Matteo, Bower, Mark, Newsom-Davis, Thomas, Sharkey, Rachel, Pria, Alessia Dalla, Rossi, Maura, Plaja, Andrea, Salazar, Ramon, Sureda, Anna, Prat, Aleix, Michalarea, Vasiliki, Van Hemelrijck, Mieke, Sita-Lumsden, Ailsa, Bertuzzi, Alexia, Rimassa, Lorenza, Rossi, Sabrina, Rizzo, Gianpiero, Pedrazzoli, Paolo, Lee, Alvin JX, Murphy, Cian, Belessiotis, Katherine, Diamantis, Nikolaos, Mukherjee, Uma, Pommeret, Fanny, Stoclin, Annabelle, Martinez-Vila, Clara, Bruna, Riccardo, Gaidano, Gianluca, D'Avanzo, Francesca, Gennari, Alessandra, Athale, Janhavi, Eichacker, Peter, Pinato, David J., Torabi-Parizi, Parizad, and Cortellini, Alessio

Published
2024
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45. Multimodal investigation of electronic transport in PTMA and its impact on organic radical battery performance

Author

Davis Thomas Daniel, Steffen Oevermann, Souvik Mitra, Katharina Rudolf, Andreas Heuer, Rüdiger-A. Eichel, Martin Winter, Diddo Diddens, Gunther Brunklaus, and Josef Granwehr

Subjects
Medicine, Science
Abstract

Abstract Organic radical batteries (ORBs) represent a viable pathway to a more sustainable energy storage technology compared to conventional Li-ion batteries. For further materials and cell development towards competitive energy and power densities, a deeper understanding of electron transport and conductivity in organic radical polymer cathodes is required. Such electron transport is characterised by electron hopping processes, which depend on the presence of closely spaced hopping sites. Using a combination of electrochemical, electron paramagnetic resonance (EPR) spectroscopic, and theoretical molecular dynamics as well as density functional theory modelling techniques, we explored how compositional characteristics of cross-linked poly(2,2,6,6-tetramethyl-1-piperidinyloxy-4-yl methacrylate) (PTMA) polymers govern electron hopping and rationalise their impact on ORB performance. Electrochemistry and EPR spectroscopy not only show a correlation between capacity and the total number of radicals in an ORB using a PTMA cathode, but also indicates that the state-of-health degrades about twice as fast if the amount of radical is reduced by 15%. The presence of up to 3% free monomer radicals did not improve fast charging capabilities. Pulsed EPR indicated that these radicals readily dissolve into the electrolyte but a direct effect on battery degradation could not be shown. However, a qualitative impact cannot be excluded either. The work further illustrates that nitroxide units have a high affinity to the carbon black conductive additive, indicating the possibility of its participation in electron hopping. At the same time, the polymers attempt to adopt a compact conformation to increase radical–radical contact. Hence, a kinetic competition exists, which might gradually be altered towards a thermodynamically more stable configuration by repeated cycling, yet further investigations are required for its characterisation.

Published
2023
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