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24 results on '"De Queiroz Crusoe, Edvan"'

1. Survival differences in multiple myeloma in Latin America and Asia: a comparison involving 3664 patients from regional registries

Author

Hungria, Vania T. M., Lee, Jae Hoon, Maiolino, Angelo, de Queiroz Crusoe, Edvan, Martinez, Gracia, Bittencourt, Rosane, Duarte, Gislaine Oliveira, Fantl, Dorotea Beatriz, Navarro, Juan Ramon, Conte, Guillermo, Gomez-Almaguer, David, Ruiz-Argüelles, Guillermo J., Kim, Kihyun, Shimizu, Kazuyuki, Chen, Wenming, Huang, Shang-YI, Chng, Wee-Joo, Chim, Chor Sang, Nawarawong, Weerasak, and Durie, Brian

Published
2019
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3. Daratumumab (Dara), Cyclophosphamide, Thalidomide and Dexamethasone for Transplant Eligible Newly Diagnosed Multiple Myeloma (TE NDMM) Patients: Response Rate Impacts on PFS

Author

De Queiroz Crusoe, Edvan, primary, Leal, Joanna, additional, Santos, Juliana Andrade, additional, Santos, Herbert Henrique de Melo, additional, Santos, Allan de souza, additional, Lucas, Larissa Ferreira, additional, Almeida, Alessandro de M., additional, Chaves, Marcos, additional, Dutra, Daniela Dourado, additional, Hungria, Vania T.M., additional, Salvino, Marco Aurelio, additional, and Arruda, Maria da Gloria B., additional

Published
2022
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5. Progression Free Survival (PFS) Analysis of Daratumumab (Dara), Cyclophosphamide, Thalidomide and Dexamethasone: A Quadruplet Intensified Treatment for Transplant Eligible Newly Diagnosed Multiple Myeloma (TE NDMM) Patients

Author

De Queiroz Crusoe, Edvan, primary, Leal, Joanna, additional, Salvino, Marco Aurelio, additional, Lucas, Larissa Ferreira, additional, Santos, Juliana Andrade, additional, Santos, Herbert Henrique de Melo, additional, Almeida, Alessandro de M., additional, Santos, Allan de souza, additional, Chaves, Marcos, additional, Santos, Mariane Melo, additional, Silva, Sarah Queiroz, additional, Vieira, Lucas de Oliveira, additional, Fonseca, Cleverson Alves, additional, Adorno, Elisangela, additional, Hungria, Vania, additional, and Arruda, Maria da Gloria B., additional

Published
2021
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6. Evaluation of Hematopoietic Stem Cell Product As a New Site for Minimal Residual Disease By Next Generation Flow in Multiple Myeloma

Author

Santos, Herbert Henrique de Melo, primary, Ribeiro, Glaciano, additional, Santos, Allan de souza, additional, Chaves, Marcos, additional, Leal, Joanna, additional, Santos, Juliana Andrade, additional, Almeida, Alessandro de M., additional, Salvino, Marco Aurelio, additional, Santos, Mariane Melo, additional, Hungria, Vania, additional, Arruda, Maria da Gloria B., additional, and De Queiroz Crusoe, Edvan, additional

Published
2021
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7. COVID-19 in Multiple Myeloma Patients: Frequencies and Risk Factors for Hospitalization, Ventilatory Support, Intensive Care Admission and Mortality -Cooperative Registry from Grupo Brasileiro De Mieloma Multiplo (GBRAM)

Author

Garnica, Marcia, primary, De Queiroz Crusoe, Edvan, additional, Ribeiro, Glaciano, additional, Bittencourt, Rosane, additional, Magalhães, Roberto José Pessoa, additional, Zanella, Karla Richter, additional, Hallack Neto, Abrahão Elias, additional, Lima, Juliana, additional, Sola, Caroline, additional, Souza, Emmanuella G, additional, Magalhaes, Andre, additional, Maiolino, Angelo, additional, and Hungria, Vania, additional

Published
2021
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10. First Description of Upfront Target Therapy Treating AML and Bcll Presented Simultaneously As First Line

Author

Carvalho, Juliana Santos, primary, Silva, Anna Flávia Silva Alves, additional, Silva, Maysa Coité, additional, Santos, Itala Gomes, additional, Aragão, Laryssa Pinto, additional, Lucas, Larissa Ferreira, additional, Santos, Herbert Henrique de Melo, additional, Botura, Mônica, additional, Rêgo, Alex Nano Magalhães, additional, Arruda, Maria da Gloria B., additional, De Queiroz Crusoe, Edvan, additional, Almeida, Alessandro de M., additional, Alves, Renata, additional, Lima, Marianna Batista Vieira, additional, Guimarães, Victor Oliveira Sousa, additional, and Salvino, Marco Aurelio, additional

Published
2020
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11. Immune Profiling Evaluation of Newly Diagnose Multiple Myeloma (NDMM) Transplant Eligible (TE) Patients Treated with Daratumumab, Cyclophosphamide, Thalidomide and Dexamethasone. Preliminary Results

Author

Santos, Allan de souza, primary, Santos, Herbert Henrique de Melo, additional, Salvino, Marco Aurelio, additional, Silva, Sarah Queiroz, additional, Lucas, Larissa Ferreira, additional, Almeida, Alessandro de M., additional, Santos, Mariane Melo, additional, Santos, Juliana Andrade, additional, Hungria, Vania T. M., additional, Arruda, Maria da Gloria B., additional, Torres, Alex, additional, and De Queiroz Crusoe, Edvan, additional

Published
2020
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12. Brazilian Real-World Multiple Myeloma (MM) Electronic Platform Register Project

Author

De Queiroz Crusoe, Edvan, primary, Ribeiro, Glaciano, additional, Zanella, Karla Richter, additional, Perobelli, Leila Martins, additional, Aranha, Milton A. F., additional, Capra, Marcelo, additional, Magalhães, Roberto José Pessoa, additional, Maciel, James, additional, Bittencourt, Rosane, additional, Souza, Emanuella, additional, Gaiolla, Rafael Dezen, additional, Braga, Walter, additional, Higashi, Fabiana, additional, Martinez, Gracia, additional, Hallack Neto, Abrahão Elias, additional, De Farias, Danielle Leao Cordeiro, additional, Farnese, Virgilio Costa, additional, Castro, Nelson S, additional, Tavares, Renato, additional, Souza, Jacqueline Holanda De, additional, Bigonha, Jandey Glória, additional, Mattos, Ederson Roberto, additional, Sola, Caroline, additional, Souto Filho, Joao Tadeu, additional, da Silva, LUiza, additional, Araujo, Cleder Aparecido Da Silva Da Silva, additional, Neto, Jorge Vaz Pinto, additional, Silva, Emanuel, additional, Hamerschlak, Nelson, additional, Nucci, Fabio Moore, additional, Ribeiro, Eduardo Flavio Oliveira, additional, Cunha, Rafael, additional, Crepaldi, Andre H, additional, Almeida, Manuella Sampaio, additional, Duarte, Gislaine B O, additional, Magalhaes, Andre, additional, Laks, Dani, additional, Daniel, Marcos, additional, Maiolino, Angelo, additional, and Hungria, Vania T. M., additional

Published
2020
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13. Preliminary Results of Daratumumab, Cyclophosphamide, Thalidomide and Dexamethasone: A Quadruplet Intensified Treatment for Newly Diagnosed Multiple Myeloma (NDMM) Transplant Eligible (TE) Patients

Author

De Queiroz Crusoe, Edvan, primary, Salvino, Marco Aurelio, additional, Silva, Sarah Queiroz, additional, Santos, Herbert Henrique de Melo, additional, Santos, Allan de souza, additional, Almeida, Alessandro de M., additional, Vieira, Lucas de Oliveira, additional, Fonseca, Cleverson Alves, additional, Lucas, Larissa Ferreira, additional, Leal, Joanna, additional, Santos, Mariane Melo, additional, Santos, Juliana Andrade, additional, Adorno, Elisangela, additional, Hungria, Vania T. M., additional, and Arruda, Maria da Gloria B., additional

Published
2020
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15. Preliminary results of Daratumumab, cyclophosphamide, thalidomide and dexamethasone- A quadruplet intensified treatment to newly diagnosed multiple myeloma transplant eligible patients

Author

de Queiroz Crusoé, Edvan, Santos, Juliana, Santos, Allan, Santos, Mariane Melo, Salvino, Marco Aurelio, Adorno, Elisangela, Moura, Alessandro, Fonseca, Cleverson Alves, Queiroz, Sarah, da Gloria Bomfim, Maria, Nicanor, Jamile, Santos, Herbert Henrique, and Hungria, Vania

Published
2019
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17. Superiority of Triple Combination Bortezomib + Cyclophosphamide and Dexamethasone (VCD) Versus Thalidomide + Cyclophosphamide and Dexamethasone (CTD) in Newly Diagnosed Multiple Myeloma Transplant-Eligible Patients

Author

De Queiroz Crusoe, Edvan, Higashi, Fabiana, Martinez, Gracia, Bittencourt, Rosane, Maiolino, Angelo, Sousa, Lais, Nunes, Renata Ferreira Marques, Ribeiro, Glaciano, Nicacio, Jandir, Zanella, Karla Richter, Magalhaes, Andre, Leao, Danielle, Pinto Neto, Jorge Vaz, Hallack Neto, Abrahão Elias, Braga, Walter, Souza, Emmanuella G, Guimaraes, Antonio Julio A.M., Durigon, Giovanna Steffenello, Laks, Dani, Kutner, Jose Mauro, Colli, Gilberto, Santucci, Rodrigo, Magalhães, Roberto José Pessoa, and Hungria, Vania T M

Published
2017
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18. Combined Analysis of 3,664 Patients with Multiple Myeloma (MM) from Latin America (LA) and Asia

Author

Hungria, Vania T M, Lee, Jae Hoon, Maiolino, Angelo, De Queiroz Crusoe, Edvan, Martinez, Gracia, Bittencourt, Rosane, Duarte, Gislaine Oliveira, Fantl, Dorotea Beatriz, Navarro, Juan Ramon, Conte, Guillermo, Gomez-Almaguer, David, Ruiz-Arguelles, Guillermo, Kim, Kihyun, Shimizu, Kazuyuki, Wenming, Chen, Huang, Shang-YI, Chng, Wee-Joo, Chim, Chor Sang, Nawarawong, Weerasak, and Durie, Brian

Published
2017
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19. For survival, the emergence of oligoclonal bands after multiple myeloma treatment is less important than achieving complete remission.

Author

Vieira da Silva, Luiza Soares, de Queiroz Crusoe, Edvan, Guimarães de Souza, Lais Rocha, Chiattone, Carlos Sérgio, and de Moraes Hungria, Vânia Tietsche

Subjects
*OLIGOCLONAL bands, *MULTIPLE myeloma, *CANCER chemotherapy, *PATIENTS
Abstract

Background: The emergence of oligoclonal bands, proteins differing from those originally identified at diagnosis, has been reported in multiple myeloma patients after high-dose chemotherapy followed by autologous stem cell transplantation and after successful conventional chemotherapy. The clinical relevance of oligoclonal bands remains unclear, but their emergence has been associated with better prognosis. The aim of the present study was to determine the prevalence, clinical characteristics and prognostic impact of the presence of oligoclonal bands in multiple myeloma patients. Methods: A retrospective cohort study was conducted. The study included newly diagnosed multiple myeloma patients with at least very good partial response after conventional dose or high-dose chemotherapy followed by autologous stem cell transplantation. The emergence of oligoclonal bands was identified using serum protein electrophoresis as well as serum and urine immunofixation techniques. Results: A total of 101 patients were included with a median follow-up of 42 months. In total, 55% were male, and the median age was 58 years (29-87 years). Fifty-one (50.5%) patients developed oligoclonal bands. They comprised 60% (45/75) of patients treated with autologous stem cell transplantation and 23% (6/26) of those who were not transplanted. Patients with oligoclonal bands showed better progression-free survival than those without the emergence of oligoclonal bands (p-value = 0.0075). Conclusion: The prevalence of oligoclonal bands in this study population was 50.5% with its frequency being greater in cases treated with autologous stem cell transplantation and in those attaining complete remission. Complete remission was more important than the emergence of oligoclonal bands on progression-free survival. [ABSTRACT FROM AUTHOR]

Published
2017
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20. Is it feasible to use granulocyte-colony stimulating factor alone to mobilize progenitor cells in multiple myeloma patients induced with a cyclophosphamide, thalidomide and dexamethasone regimen?

Author

de Queiroz Crusoe, Edvan, Higashi, Fabiana, Martinez, Gracia Aparecida, Barros, José Carlos, Bellesso, Marcelo, Rossato, Marina, Marret, Ana Cinira F., Chiattone, Carlos Sérgio, and de Moraes Hungria, Vania Tietsch

Subjects
*GRANULOCYTE-colony stimulating factor, *CYCLOPHOSPHAMIDE, *MULTIPLE myeloma treatment
Abstract

Background: Cyclophosphamide plus thalidomide as induction for multiple myeloma patients eligible for autologous stem cell transplantation may be a limiting factor for cell mobilization. The minimum acceptable mobilized peripheral blood stem cell count to prevent deleterious effects during transplantation is 2.0 × 106 CD34+ cells/kg. Combining other treatments to granulocyte-colony stimulating factor, such as cyclophosphamide, could overcome the mobilization limitation. The objective of this study was to assess the number of CD34+ cells mobilized using granulocyte-colony stimulating factor with and without cyclophosphamide after induction with cyclophosphamide, thalidomide and dexamethasone. Methods: A retrospective study was performed of a cohort of multiple myeloma patients submitted to autologous stem cell transplantations at two Brazilian centers between May 2009 and July 2013. The oral cyclophosphamide and thalidomide induction doses used were 1500 mg/month and 100-200 mg/day, respectively. Mobilization doses were 10-15 mcg/kg granulocyte-colony stimulating factor with 2-4 g/m2 cyclophosphamide, or 15-20 mcg/kg granulocyte-colony stimulating factor alone for 5 days. Collection of >2.0 × 106 CD34+ cells/kg was considered sufficient. Results: Eighty-eight patients were analyzed; only 18 received cyclophosphamide. The median age was 58 years old (range: 51-62) for the granulocyte-colony stimulating factor group and 56.5 years old (range: 54-60) for granulocyte-colony stimulating factor plus cyclophosphamide group. Fifty-two patients were male. Eighty cases (90.9%) were Durie- Salmon Staging System III-A/B and 38 (44.7%) and 20 cases (23.5%) were International Staging System 2 and 3, respectively. The group that received cyclophosphamide collected a higher median number of progenitor cells [3.8 (range: 3.1-4.4) vs. 3.2 (range: 2.3-3.8)] (p-value = 0.008). No correlation was observed between better responses or number of induction cycles and the number of cells collected. Conclusion: The number of cells mobilized with granulocyte-colony stimulating factor plus cyclophosphamide was higher. However, in both groups, the median number of CD34+ cells was sufficient to perform a single autologous stem cell transplantation; no deleterious effects were reported during harvesting. [ABSTRACT FROM AUTHOR]

Published
2016
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21. Bilateral breast plasmacytoma: a clinical case report.

Author

da Cunha Fischer, Thais Rodrigues, Higashi, Fabiana, de Queiroz Crusoe, Edvan, and de Moraes Hungria, Vania Tietsche

Abstract

The article discusses the case of a 52-year-old woman patient who was admitted to the hospital due to asthenia and diagnosed with extramedullary breast plasmacytoma.

Published
2016
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22. Transcriptomic rationale for the synergy observed with dasatinib + bortezomib + dexamethasone in multiple myeloma

Author

de Queiroz Crusoe, Edvan, primary, Maiso, Patricia, additional, Fernandez-Lazaro, Diego, additional, San-Segundo, Laura, additional, Garayoa, Mercedes, additional, Garcia-Gomez, Antonio, additional, Gutierrez, Norma C., additional, Delgado, Manuel, additional, Colado, Enrique, additional, Martin-Sanchez, Jesus, additional, Lee, Francis Y., additional, and Ocio, Enrique M., additional

Published
2011
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23. Guidelines on the diagnosis and management of multiple myeloma treatment: Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular Project guidelines: Associação Médica Brasileira - 2012.

Author

de Moraes Hungria, Vânia Tietsche, de Queiroz Crusoe, Edvan, Quero, Adriana Alvarez, Sampaio, Manuella, Maiolino, Angelo, and Bernardo, Wanderley Marques

Subjects
*MULTIPLE myeloma diagnosis, *PROGNOSIS, *IMMUNOGLOBULINS, *PROCEDURE manuals, *PLASMA cells
Abstract

The article discusses the parameters that shoould be used for clinical diagnosis, the evaluation of severity and standardized treatment that can be used by hematologists in the treatment of patients with multiple myeloma (MM). It mentions that MM is a disorder characterized by the abnormal proliferation of plasmocytes in the bone marrow that results to the production of immunoglobulins. It also discusses the way prognosis can be done to patients with MM.

Published
2013
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24. [Not Available].

Author

de Queiroz Crusoe E, Higashi F, Camargo Padilha MP, Miranda EC, Quero AA, Almeida Mde S, Peres AL, Cury P, Chiattone C, Barros JC, and de Moraes Hungria VT

Published
2014
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