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1. Seasonal rhythms of vasopressin release and aquaporin-2 excretion assure appropriate water conservation in humans

Author

Goswami, N, Di Mise, A, Centrone, M, Russo, A, Ranieri, M, Reichmuth, J, Brix, B, De Santo, N, Sasso, F, Tamma, G, Valenti, G, Goswami N., Di Mise A., Centrone M., Russo A., Ranieri M., Reichmuth J., Brix B., De Santo N. G., Sasso F. C., Tamma G., Valenti G., Goswami, N, Di Mise, A, Centrone, M, Russo, A, Ranieri, M, Reichmuth, J, Brix, B, De Santo, N, Sasso, F, Tamma, G, Valenti, G, Goswami N., Di Mise A., Centrone M., Russo A., Ranieri M., Reichmuth J., Brix B., De Santo N. G., Sasso F. C., Tamma G., and Valenti G.

Published
2021

3. Another case of organ blindness in the history of combined eye-kidney disorders wilson’s disease

Author

Viggiano D., De Santo N. G., Simonelli F., Capasso G., Viggiano, D., De Santo, N. G., Simonelli, F., and Capasso, G.

Subjects
Organ blindne, Wilson’s disease, Carl Westphal’s pseudosclerosi
Abstract

Wilson’s disease, or hepatolenticular degeneration, is a rare genetic disorder of copper metabolism. The disease leads to the accumulation of copper in the brain, liver, eyes and kidney. The dominant triad of the syndrome is nodular liver cirrhosis, Kayser-Fleischer ring in the corneas, lesions of the cortex and basal ganglia. In addition, a defect in proximal tubule reabsorption has been noted. The syndrome has been named after Samuel Alexander Kinnier Wilson (1878–1937). It was initially considered a purely brain disease, described by Frerichs in 1861. In 1883, Carl Westphal in Germany described two cases of what he termed “pseudosclerosis”. These and other reports led Wilson to pro-pose the existence of the new clinical entity with degeneration of the brain lenticular nucleus and of the liver in 1912. “Pseudosclerosis” and “Wilson’s disease” were later found to be the same disease. In 1913, Rumpel introduced the study of copper in the liver in a case of pseudosclerosis. The renal dysfunction included the discovery of aminoaciduria, glycosuria, increased urate excretion, reduced renal plasma flow (RPF) and glomerular filtration rate (GFR), and specific histological lesions. A complete physiological study of the kidney was then presented in 1957 by Bearn and Gutman, who confirmed the reduced RPF and reduced GFR, and reduced secretory and reabsorptive tubular function. The ocular findings in Wilson’s disease were identified in 1902 by Bernhard Kayser and Bruno Fleischer in Germany, who first described the typical ring in the cornea that still brings their names. In conclusion, the history of renal and eye involvement in Wilson’s disease appears as another case of organ blindness; that is, attention to the predominant symptom leads to neglecting the involvement of other organs in multisystemic diseases. The sequence of discoveries and hypotheses reflects the technical advancement of each specific historical period.

Published
2020

7. Royal academy of medicine in Ireland international conference on homocysteine metabolism from basic science to clinical medicine: Proceedings of meeting held at Dromoland Castle, Co. Clare on July 2nd–6th, 1995

Author

Björkegren, K., Bergmark, C., de Faire, U., Mansoor, M. Azam, Svardal, A., Bostom, A. G., Roubenoff, R., Dellaripa, P., Nadeau, M. R., Sutherland, P., Wilson, P. W. F., Jacques, P. F., Selhub, J., Rosenberg, I. H., Bostom, A. G., Brosnan, J. T., Hall, B., Nadeau, M. R., Selhub, J., Bostom, A. G., Shemin, D., Lapane, K. L., Sutherland, P., Nadeau, M. R., Wilson, P. W. F., Selhub, J., Bostom, A. G., Shemin, D., Nadeau, M. R., Selhub, J., Bostom, A. G., Selhub, J., Jacques, P. F., Nadeau, M. R., Williams, R. R., Ellison, R. C., Cuskelly, G. J., McNulty, H., Strain, J. J., McPartlin, J. M., Scott, J. M., Chadefaux-Vekemans, B., Coudé, M., Aupetit, J., Kamoun, P., Coudé, M., Aral, B., Zabot, M. T., Aupetit, J., Kamoun, P., Chadefaux-Vekemans, B., Calaf, R., Ghiringelli, O., Barlatier, A., Charpiot, P., Rolland, P. H., Garçon, D., Charpiot, P., Augier, T., Chareyre, C., Rolland, P. H., Garçon, D., Chango, A., Hodez, F., Tronel, H., Nuel, G., Michel, F., Frémont, S., Méjean, L., Nicolas, J. P., Candito, M., Chambon, P., Gibelin, P., Amsellem, J., Baudouy, M., Morand, P., Candito, M., Chambon, P., Pringuey, D., Aubin-Brunet, V., Beaulieu, F., Darcourt, G., Bedoucha, P., Alchaar, H., Chatel, M., Candito, M., de Valk, H. W., van der Griend, R., Eeden, M. K. G. van, de Groot, E., Duran, M., Smeitink, J. A. M., de Klerk, J. B. C., Wittebol-Post, D., Rolland, M. -O., Haas, F. J. L. M., Meuwissen, O. J. A. Th., Banga, J. D., Poll-The, B. T., de Vries, J. I. P., Dekker, G. A., van Geijn, H. P., Huigens, P. C., Jakobs, C., von Blomberg, B. M. E., Deulofeu, R., Giralt, M., Aibar, C., Bauchet, C., Ballesta, A. M., Varela, G., Vila, N., Chamorro, A., Casals, F. J., Cremades, J. Diaz, Daly, L., Meleady, R., Graham, I., den Heijer, M., Brouwer, I. A., Gerrits, W. B. J., Bos, G. M. J., Blom, H. J., den Heijer, M., Bos, G. M. J., Koster, T., Vandenbroucke, J. P., Blom, H. J., Briët, E., Rosendaal, F. R., Fischer, G., Behrend, C., Bartholmes, P., Fermo, I., Paroni, R., Vigano, S., D’Angelo, A., Fermo, I., Paroni, R., Vigano, S., D’Angelo, A., Franken, D. G., Boers, G. H. J., Blom, H. J., Hamel, B. C. J., Franken, D. G., Boers, G. H. J., Blom, H. J., Ruijs, J. H. J., Franken, D. G., Blom, H. J., Boers, G. H. J., Tangerman, A., Guttormsen, A. B., Ueland, P. M., Refsum, H., Svarstad, E., Gao, W., Goldman, E., Jakubowski, H., Sebastio, G., Sperandeo, M. P., de Franchis, R., Andria, G., Garrow, T. A., Hladovec, J., Sommerova, Z., Písariková, A., Halsted, C. H., Villanueva, J., Chandler, C. J., Stabler, S. P., Allen, R. H., Muskhelishvili, L., James, S. J., Poirer, L., Jacobsen, D. W., Savon, S. R., DiCorleto, P. E., Jourdheuil-Rahmani, D., Rolland, P. H., Garçon, D., Joosten, E., Riezler, R., Allen, R., Joosten, E., Riezler, R., Allen, R., Marquardt, T., Ullrich, K., Harms, E., Koch, H. G., Koch, H. G., Evers, S., Grotemeyer, K. H., Vogelpohl, L., von Eckardstein, A., Ullrich, K., Deufel, T., Kraus, J., Harms, E., Kozich, V., Janosik, M., Sokolová, J., Bukovská, G., Kraus, J. P., Kluitmans, L. A. J., van den Heuvel, L. P., Stevens, E., Trubels, J. M. F., Blom, H. J., Boers, G. H. J., van Oost, B. A., Kraus, J. P., Kittner, S., Macko, R., Hebel, J. R., Rohr, J., Malinow, M. R., Upson, B., Buchholz, D., Earley, C., Johnson, C., Price, T. R., Rosario, J., Sloan, M., Stern, B., Wityk, R., Wozniak, M., Sherwin, R., Stolley, P., Kluijtmans, L., Heuvel, L. van den, Stevens, E., Trijbels, F., Blom, H., Boers, G., van Oost, B., den Heijer, M., Rozen, R., Löhrer, F., Angst, C., Fowler, B., Zaugg, M., Brunner, F., Haefeli, W. E., Nedrebø, B., Ericsson, U. -B., Ueland, P. M., Refsum, H., Lien, E. A., London, J., Paly, E., Paul, V., Paris, D., Kamoun, P., Chassé, J. F., Møller, J., Rasmussen, K., Meleady, R., Graham, I., Daly, L., Verhoef, P., Meleady, R., Graham, I., Daly, L., McMartin, K. E., Phifer, T. J., Alexander, J. S., Middlebrooks, M., Childress, L. E., Nicolas, J. P., Tronel, H., Chango, A., Fremont, S., Felden, F., Guerci, B., Creton, C., Drouin, P., Oakley, G. P., Elias, P. R. P., Hann, A. C., Curtis, C. G., Rose, F. A., Tudball, N., Parrot-Roulaud, F., Cochet, C., Catargi, B., Leprat, F., Latapie, J. -L., Perna, A. F., De Santo, N. G., Ingrosso, D., Galletti, P., Zappia, V., Parrot-Roulaud, F., Sassoust, G., Boissieras, P., Blom, H. J., Majors, A. K., Ehrhart, L. A., Pezacka, E. H., Perry, I. J., Morris, R. W., Ebrahim, S. B., Shaper, A. G., Refsum, H., Ueland, P. M., Pietrzik, K., Dierkes, J., Kroesen, M., Bung, P., Rasmussen, K., Moller, J., Rasmussen, K., Remacha, A., Garcia-Die, F., Cadafalch, J., Barceló, H. J., Parellada, H., Regland, B., Gottfries, C. -G., Andersson, M., Bagby, J., Dyrehag, L. -E., Abrahamsson, L., Ronge, E., Kjellman, B., Frosst, P., Christensen, B., Goyette, P., Rosenblatt, D. S., Genest, J., Rozen, R., Riedel, B., Ueland, P. M., Svardal, A. M., Silberberg, J., Crooks, R., Fryer, J., Ray, C., Guo, X. W., Xie, L., Dudman, N., Silberberg, J., Crooks, R., Fryer, J., Ray, C., Guo, X. W., Xie, L., Dudman, N., Silberberg, J., Crooks, R., Fryer, J., Ray, C., Guo, X., Xie, L., Dudman, N., Smith, B., Kohlman-Trigoboff, D., Simsir, S., Stabler, S. P., Allen, R. H., Strydom, A. J. C., Schlüssel, E., Preibisch, G., Elstner, E. F. E., Pütter, S., Spuijbroek, M. D. E. H., Goddijn-Wessel, T. A. W., Wouters, M. G. A. J., Molen, E. F. v. d., Blom, H. J., Boers, G. H. J., Steegers-Theunissen, R. P. M., Trijbels, J. M. F., Thomas, C. M. G., Eskes, T. K. A. B., Tsai, M. Y., Hanson, N., Key, N., Schwichtenberg, K., Garg, U., Todesco, L., Fowler, B., Pollaert, N., Haefeli, W. E., Thorand, B., Hages, M., Pietrzik, K., Bung, P., Holzgreve, W., Vila, N., Chamorro, A., Deulofeu, R., Aibar, C., Giralt, M., Ballesta, A. M., van der Mooren, M. J., Wouters, M. G. A. J., Schellekens, L. A., Eskes, T. K. A. B., Rolland, R., Blom, H. J., Put, N. v. d., Trijbels, F., Heuvel, L. v. d., Blom, H., Eskes, T., Steegers-Theunissen, R., Mariman, E., Heyer, M. d., Rozen, R., Daher, R., Van Lente, F., Vilkovsky, A. B., Maev, I. V., Richter, E. L., Kirnus, M. D., Varela-Moreiras, G., Alonso-Aperte, E., Rubio, M., Gassó, M., Deulofeu, R., Alvarez, L., Caballeria, J., Rodés, J., Mato, J. M., van Aerts, L. A. G. J. M., Peereboom-Stegeman, J. H. J. Copius, Noordhoek, J., Eskes, T. K. A. B., Molen, E. F. v. d., Spuijbroek, M. D. E. H., Eskes, T. K. A. B., Heuvel, L. P. v. d., Monnens, L. A. H., Blom, H. J., van Guidener, C., Janssen, M. J. F. M., Surachno, J., Stehouwer, C. D. A., van den Berg, M., Bierdrager, E., Rauwerda, J. A., Wilcken, B., Hammond, J., Wouters, M. G. A. J., Hamilton, C. J. C. M., Blom, H. J., Boers, G. H. J., Thomas, C. M. G., Borm, G. F., Eskes, T. K. A. B., Wang, H., Tsai, J. -C., Perrella, M. A., Yoshizumi, M., Sibinga, N. E. S., Haber, E., Chang, T. H. -T., Schlegel, R., Lee, M. -E., Woodside, J., McMaster, D., Yarnell, J., Young, I., Mercer, C., Byrne, K., Evans, A., Gey, F., Gao, X. M., Dougan, G., Wordsworth, P., McMichael, A., Young, P. B., Kennedy, D. G., Molloy, A. M., Scott, J. M., Ward, P., Naughten, E., Cahalane, S., Murphy, D., Mayne, P., Chauveau, P., Chadefaux-Vekemans, B., Coudé, M., Aupetit, J., Kamoun, P., Jungers, P., van Asselt, D. Z. B., Blom, H. J., de Wild, G. M., van Staveren, W. A., Hoefnagels, W. H. L., Naruszewicz, M., Staniewicz, A., Dziewanowski, K., Evrovski, J., Cole, D. E. C., Callaghan, Michael, Lindgren, A., Brattström, L., Hultberg, B., Verhoef, P., Hennekens, C. H., Allen, R. H., Stabler, S. P., Willett, W. C., Stampfer, M. J., Frantzen, F., Sundrehagen, E., Verhoef, P., Kok, F. J., Stampfer, M. J., Willett, W. C., Gaziano, J. M., Hennekens, C. H., Allen, R. H., Stabler, S. P., Reynolds, R. D., Hsu, R. -J., Shane, B., Robinson, K., Kottke-Marchant, K., Green, R., Gupta, A., Jacobsen, D., Robinson, K., Mayer, E., Gupta, A., Miller, D., Marchant, K., Green, R., Jacobsen, D., Greene, R., Chong, Y. -Y., Jacobsen, D., Robinson, K., Gupta, M., Sheppard, C. A., Matthews, R. G., Goyette, P., Frosst, P., Rozen, R., Verhoef, P., Kok, F. J., Kruyssen, H. A. C. M., Witteman, J. C. M., Ueland, P. M., Boushey, C., Beresford, S., Omenn, G., Motulsky, A. G., Nygard, O., Vollset, S. E., Kvale, G., Stensvold, I., Ueland, P. M., Refsum, H., Fiskerstrand, T., Ueland, P. M., Refsum, H., Bugge, K. H., Oshaug, A., Bjønnes, C. H., Refsum, H., Wu, J. T., Wu, L. L., and Wilson, L. W.

Published
1995
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17. Thyroid Function in Children on CAPD

Author

De Santo, N. G., Carella, C., Fine, R. N., Leumann, E., Fine, S., Amato, G., Capodicasa, G., Nuzzi, F., De Simone, V., Capasso, G., Lama, G., Scoppa, F., Giordano, C., Fine, Richard N., editor, Schärer, Karl, editor, and Mehls, Otto, editor

Published
1985
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20. Un modello HTA a sostegno dell’offerta della dieta ipoproteica ai nefropatici della Campania

Author

Liguori, G., Belfiore, P., Cianciaruso, B., Cirillo, Massimo, Creazzola, S., D'Ausilio, A., De Santo, N. G., La Bella, G., Parlato, A., Scaletti, A., Zamparelli, B., Liguori, G., Belfiore, P., Cianciaruso, B., Cirillo, M., Creazzola, S., D'Ausilio, A., De Santo, N. G., La Bella, G., Parlato, A., Scaletti, A., and Zamparelli, B.

Subjects
dieta ipoproteica
Abstract

Una delle conseguenze più importanti dell'insufficienza renale cronica (IRC) è il ricorso al trattamento dialitico: nella sola Campania sono oggi 5.000 i nefropatici in terapia dialitica, a fronte dei 45.000 dell'intera penisola. In letteratura è oramai riconosciuta l'importanza della dieta ipoproteica nel rallentare la progressione della patologia e dunque procrastinare l'accesso alla dialisi. Se a ciò si aggiunge che il costo del trattamento dialitico è di gran lunga superiore rispetto a quello della dieta, ne consegue che grazie alle dialisi evitate, si otterrebbero non solo ripercussioni positive sul benessere dei pazienti, ma altresì vantaggi economici nell'ottica del management sanitario. Al fine di sostenere questa tesi, nell'ambito di una valutazione di Health Technology Assessment (HTA) è stato implementato un modello di budget impact analisys attraverso il quale testare la reale convenienza economica della elargizione della dieta ipoproteica ai nefropatici della Campania. Il modello implementato prende in considerazione i soli costi diretti a carico del SSN; in particolare, vengono messi a confronto la spesa per le dialisi evitate e quelli della dieta con alimenti ipoproteici, in uno scenario che valuta differenti indici di NNT (Number Needed to Treat) e di compliance (aderenza + persistenza al trattamento). I risultati consentono di sostenere l'offerta della dieta ai nefropatici in fase pre-dialitica, vale a dire con eGFR >45 che, nel caso di specie e relativamente all'anno 2009, sono rappresentati da 25.000 soggetti. É opportuno però sottolineare che i risultati a sostegno della tesi principale appaiono subordinati al rispetto di una aderenza al trattamento di almeno il 50%, piuttosto che di un NNT non superiore a 50. In quest'ottica, gli AA sostengono che una distribuzione per conto dei suddetti prodotti, da parte delle farmacie territoriali, potrebbe rappresentare una scelta appropriata in quanto consentirebbe di usufruire di un prezzo scontato e, allo stesso tempo, di realizzare un setting favorente per aumentare l'aderenza al trattamento.

Published
2012

22. Bone composition and the birth of quantitative chemistry

Author

De Santo, N. G., DE Santo, R. M., Pisot, R., Bisaccia, C., Perna, A., Bizzarri, M., Di Leo, V. A., Bilancio, Giancarlo, Cirillo, Massimo, De Santo, Ng, De Santo, Rm, Pisot, R, Bisaccia, C, Perna, Alessandra, Bizzarri, M, Di Leo, Va, Bilancio, G, Cirillo, M., De Santo, N. G., DE Santo, R. M., Pisot, R., Bisaccia, C., Perna, A., Bizzarri, M., Di Leo, V. A., and Bilancio, G.

Subjects
lcsh:Sports, lcsh:GV557-1198.995, medicina aerospaziale
Abstract

Bone is an important tissue for space specialists since it undergoes significant changes under microgravity conditions and its healing is slow. Bone has been considered a special tissue since the very inception of medical theories. In Akragas, Empedocles' (493-432 BC) hypothesis regarding bone was that it was made of two parts earth, two parts water and four parts fire, thus marking the beginning of quantitative chemistry.

Published
2011

23. The Nature of Water

Author

De Santo, R. M., Bisaccia, Carmela, De Santo, N. G., De Santo, R. M., Bisaccia, Carmela, and De Santo, N. G.

Subjects
Hydrology, Water--Philosophy, Water in art
Abstract

Water, the most represented substance in the human body, is a trace of the primordial sea where life originated. Its virtues may be represented by the Venus of Botticelli coming out from the sea, as well as by Velasquez's water seller and by Aristophanes'chant of the clouds. Water has been connected with medicine from time immemorial and is a common good. For Sumerians, the physician was the man who new water. Homer's (850-750 BC) mythical tradition made Ocean and Thetys progenitors of all gods and of the world. Hesiod (ca. 700 BC) chanted Poseidon, the sea-lake god, who could cause tempests and seaquakes, generate springs, and also confer the power to walk on water like on earth.

Published
2013

26. A new biotechnological approach to reduce the increase of the protease concentration during extracorporeal blood circulation in hemodialysis or cardiopulmonary bypass operations

Author

V. GRANO, N. DIANO, U. BENCIVENGA, DE SANTO N. G., SALAMINO F., COTRUFO M., NAPPI, Gianantonio, DE SANTO L. S., CASADIO R., COMPIANI M., CITTON C., D. G. MITA, NOHAN H., V., Grano, N., Diano, U., Bencivenga, DE SANTO, N. G., Salamino, F., Cotrufo, M., Nappi, Gianantonio, DE SANTO, L. S., Casadio, R., Compiani, M., Citton, C., and D. G., Mita

Published
2004

27. Acqua per dialisi

Author

ANASTASIO, Pietro, CORREALE G, DI STAZIO E, CHIRICONE D, FRANGIOSA A, DE SANTO N. G., Anastasio, Pietro, Correale, G, DI STAZIO, E, Chiricone, D, Frangiosa, A, and DE SANTO, N. G.

Published
2004

30. INSUFFICIENZA RENALE ACUTA

Author

PERNA, Alessandra, DI STAZIO E., DE SANTO N. G., DE SANTO N.G., CAMUSSI G., D'ARMIENTO M., Perna, Alessandra, DI STAZIO, E., and DE SANTO, N. G.

Published
2003

31. Il Registro dell’uremia in Campania

Author

IORIO B, AVELLA F, CIRILLO M, DE SANTO N. G., FEDERICO, STEFANO, Iorio, B, Avella, F, Federico, Stefano, Cirillo, M, and DE SANTO, N. G.

Published
2003

32. Il rene nell’anziano

Author

COPPOLA S, DE SANTO N. G., CAPASSO, Giovambattista, Coppola, S, Capasso, Giovambattista, and DE SANTO, N. G.

Published
2003

33. INSUFFICIENZA RENALE CRONICA

Author

PERNA, Alessandra, DI STAZIO E., SATTA E., DE SANTO N. G., DE SANTO N.G., CAMUSSI G., D'ARMIENTO M., Perna, Alessandra, DI STAZIO, E., Satta, E., and DE SANTO, N. G.

Published
2003

34. The α 1 -antitrypsin/elastase complex as an experimental model for hemodialysis in acute catabolic renal failure, extracorporeal blood circulation and cardiocirculatory bypass

Author

GRANO V, DIANO, Nadia, BENCIVENGA U, DE MAIO A, DE SANTO N, PERNA, Alessandra, SALAMINO F, MITA D. G., PORTACCIO, Marianna Bianca Emanuela, Grano, V, Diano, Nadia, Portaccio, Marianna Bianca Emanuela, Bencivenga, U, DE MAIO, A, DE SANTO, N, Perna, Alessandra, Salamino, F, and Mita, D. G.

Subjects
Extracorporeal blood circulation, Acute renal failure, Antiprotease, α, Polyethersulphone membrane, Cardiopulmonary bypa, Antitrypsin/elastase complex, Protease
Abstract

A modified polyethersulphone graft membrane was loaded with antiproteases, with the aim of reducing the active protease blood concentration during hemodialysis in acute catabolic renal failure or cardiopulmonary bypass. As protease/antiprotease system, elastase and α 1 -antitrypsin were used. The concentration of active elastase in aqueous solutions decreased as function of contact time with the membrane, approaching saturation. A 40% loss of elastase activity was obtained at pH 7.4, which was not due to autolysis, which accounted for 5% of the loss. The highest reduction was achieved at pH 9.0 (25% higher than at pH 7.4). The saturation level of elastase decrease, calculated by means of the Einstein equation, was reached after more than 47 minutes. We speculate that a time reduction might be achieved either increasing the concentration of immobilized antiproteases, or increasing the rate of elastase movement across the membranes by hydraulic, osmotic, or temperature gradients. This technology can be applied to hemodialysis, and in extracorporeal blood circulation to promote elastase release.

Published
2002

35. The alfa1-antitrypsin/elastase complex a san experimental model for hemodialysis in acute catabolic renal failure; extracorporeal blood circulation and cardiocirculatory bypass

Author

Grano V., Diano N., Portaccio M., Bencivenga U., De Santo N., Perna A., Salamino F., Mita D. G. ., DE MAIO, ANNA, Grano, V., Diano, N., Portaccio, M., Bencivenga, U., DE MAIO, Anna, De Santo, N., Perna, A., Salamino, F., and Mita, D. G. .

Subjects
alpha1-antitrypsin/elastase complex, model for hemodialysi
Abstract

A modified polyethersulphone graft membrane was loaded with antiproteases, with the aim of reducing the active protease blood concentration during hemodialysis in acute catabolic renal failure or cardiopulmonary bypass. As protease/antiprotease system, elastase and alpha1-antitrypsin were used. The concentration of active elastase in aqueous solutions decreased as function of contact time with the membrane, approaching saturation. A 40% loss of elastase activity was obtained at pH 7.4, which was not due to autolysis, which accounted for 5% of the loss. The highest reduction was achieved at pH 9.0 (25% higher than at pH 7.4). The saturation level of elastase decrease, calculated by means of the Einstein equation, was reached after more than 47 minutes. We speculate that a time reduction might be achieved either increasing the concentration of immobilized antiproteases, or increasing the rate of elastase movement across the membranes by hydraulic, osmotic, or temperature gradients. This technology can be applied to hemodialysis, and in extracorporeal blood circulation to promote elastase release.

Published
2002

41. Tubular function in liver cirrhosis

Author

ANASTASIO, Pietro, FRANGIOSA A, CAPODICASA L, PAPALIA T, DE NAPOLI N, DEL VECCHIO BLANCO C, DE SANTO N., LOGUERCIO, Carmelina, DE SANTO, CIRILLO, PAPALIA, DE NAPOLI, Anastasio, Pietro, Frangiosa, A, Capodicasa, L, Papalia, T, Loguercio, Carmelina, DE NAPOLI, N, DEL VECCHIO BLANCO, C, and DE SANTO, N.

Published
2000

43. Effect of computer-assisted European Best Practice Guideline implementation on adherence and target attainment: ORAMA results

Author

Covic, A, Locatelli, F, Macdougall, Ic, Wiecek, A, Shikov, P, Nikolov, D, Deliyska, B, Paskalev, D, Simeonov, P, Belavic, Z, Jerko, B, Leko, N, Bogadi, I, Winkler, Re, Buhl, M, Wilbrandt, E, Edinger, M, Mall, M, Dammerboer, C, Urzowski, H, Flender, D, Kunowski, G, Müller, A, Anschütz, H, Prager, G, Lüth, Jb, Gaspare De Santo, N, Lodeserto, C, Bonomini, M, Meneghel, G, Ragaiolo, M, Cancarini, Giovanni, Rotolo, U, Zepa, L, Saumane Baza, G, Rivots, G, Rozentals, R, Rydzewski, A, Antczak Jedrzejczak, D, Ratajewski, W, Frankiewicz, D, Mazur, O, Grazyna, B, Kosicki, A, Sydor, A, Muszytowski, M, Mircescu, G, Mugosa Ratkovic, M, Pljesa, S, Nesic, V, Dimkovic, N, Curic, S, Lazarevic, M, and Kovacevic, Z.

Subjects
hemodialysis, erhythropoietin, anemia
Published
2009

48. 'Renal Reserve'

Author

De Santo N. G., CAPASSO, Giovambattista, De Santo, N. G., and Capasso, Giovambattista

Published
1995

50. A new biotechnological approach to reduce the increase of the protease concentration during extracorporeal blood circulation in hemodyalisis or cardiopulmonary bypass operations

Author

GRANO V., DIANO N., BENCIVENGA U., DE SANTO N. G., SALAMINO F., COTRUFO M., NAPPI G. A., DE SANTO L. S., COMPIANI M., CITTON C., OLIVA A., MITA D. G., CASADIO, RITA, S.G.PANDALAI, GRANO V., DIANO N., BENCIVENGA U., DE SANTO N.G., SALAMINO F., COTRUFO M., NAPPI G.A., DE SANTO L.S., CASADIO R., COMPIANI M., CITTON C., OLIVA A., and MITA D.G.

Published
2004

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