Search

Your search keyword '"De Sousa, Ricardo Augusto Leoni"' showing total 122 results
Start Over Author "De Sousa, Ricardo Augusto Leoni"
122 results on '"De Sousa, Ricardo Augusto Leoni"'

3. Overexpression of miR-126-5p in the serum of patients with systemic arterial hypertension is correlated with creatinine and platelets

Author

Improta-Caria, Alex Cleber, primary, Nonaka, Carolina Kymie Vasques, additional, Aras, Marcela Gordilho, additional, Nunes, Bianca Almeida, additional, De Sousa, Ricardo Augusto Leoni, additional, Oliveira, Edilamar Menezes, additional, Roever, Leonardo, additional, Souza, Bruno Solano Freitas, additional, and Aras-Júnior, Roque, additional

Published
2024
Full Text
View/download PDF

9. Nandrolone decanoate reduces the positive effects of resistance training on cognition, anxious behavior, and hippocampal morphology in rats

Author

Magalhães, Caíque Olegário Diniz e, primary, de Oliveira, Lucas Renan Sena, additional, Santos, Stefanyne Teixeira, additional, Mendes, Bruno Ferreira, additional, Dias, Isabella Rocha, additional, Cruz, Poliany Pereira, additional, Sampaio, Kinulpe Honorato, additional, Peixoto, Marco Fabrício Dias, additional, De Sousa, Ricardo Augusto Leoni, additional, and Cassilhas, Ricardo Cardoso, additional

Published
2022
Full Text
View/download PDF

23. A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement

Author

Gripp, Fernando, primary, de Jesus Gomes, Gilton, primary, De Sousa, Ricardo Augusto Leoni, primary, Alves de Andrade, Júllia, primary, Pinheiro Queiroz, Ilkilene, primary, Diniz Magalhães, Caíque Olegário, primary, Cassilhas, Ricardo Cardoso, primary, de Castro Magalhães, Flávio, primary, Amorim, Fabiano Trigueiro, primary, and Dias-Peixoto, Marco Fabrício, primary

Published
2022
Full Text
View/download PDF

24. Accumulated High-intensity Interval Training Protocol: A New Approach to Study Health Markers in Wistar Rats

Author

De Sousa, Ricardo Augusto Leoni, primary, Mendes, Bruno Ferreira, primary, Costa-Pereira, Liliane, primary, de Souza Pereira, Ramona Ramalho, primary, de Andrade, Júllia Alves, primary, Diniz e Magalhães, Caíque Olegário, primary, Gripp, Fernando, primary, Magalhães, Flávio de Castro, primary, Andrade, Eric Francelino, primary, Cassilhas, Ricardo Cardoso, primary, and Dias-Peixoto, Marco Fabrício, primary

Published
2022
Full Text
View/download PDF

26. Neurological consequences of exercise during prenatal Zika virus exposure to mice pups.

Author

De Sousa, Ricardo Augusto Leoni, Peixoto, Marco Fabrício Dias, Leite, Hércules Ribeiro, Oliveira, Lucas Renan Sena de, Freitas, Daniel Almeida, Silva-Júnior, Fidelis Antonio da, Oliveira, Henoque Santos, Rocha-Vieira, Etel, Cassilhas, Ricardo Cardoso, and Oliveira, Danilo Bretas de

Subjects
*ZIKA virus, *PRENATAL depression, *SWIMMING training, *NEUROBEHAVIORAL disorders, *PRENATAL exposure, *CEREBRAL atrophy
Abstract

Zika virus (ZIKV) infection during the pregnancy period is related to microcephaly and neurobehavioral disorders at birth, while prenatal exercise is supposed to provide neuroprotection in newborns pups. The aim of this study was to investigate the neurological consequences of exercise during prenatal ZIKV exposure to mice pups. Twelve weeks female mice were randomly assigned into three groups: Control group, intraperitoneally injected with saline (Control); untrained group, intraperitoneally injected with ZIKV (ZIKV); and trained group, intraperitoneally injected with ZIKV (ZIKV/swim). There was one familiarization week prior to the beginning of the swimming training. Dams swam for 60 min/session, 5 days/week, during 4 weeks. Mating occurred between the fifth and seventh day of the first week of the swimming training. ZIKV 106 plaque-forming units/100 µl (106 PFUs/100 µl) or an equal volume of saline was intraperitoneally injected in the pregnant mice at embryonic day 10.5. Pup's body mass and brain weight were measured at postnatal day 1 (P1). Behavioral tests were performed from P30 to P35. Thereafter, hippocampal levels of syntaxin-1, GFAP, IBA-1, and BDNF were measured. Exercise during prenatal ZIKV exposure prevented brain atrophy, development of depression, anxiety, and disruption of social behavior. Exercise during prenatal ZIKV exposure inhibited the overexpression of microglia (IBA-1) and astrocytes (GFAP), with reduction of BDNF levels in the hippocampi of female and male mice pups. No significant changes were seen in syntaxin-1 levels. Our findings reveal beneficial effects of exercise during pregnancy exposure to ZIKV in mice pups. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

30. Moderate-intensity continuous training and high-intensity interval training improve cognition, and BDNF levels of middle-aged overweight men

Author

de Lima, Neumir Sales, primary, De Sousa, Ricardo Augusto Leoni, additional, Amorim, Fabiano Trigueiro, additional, Gripp, Fernando, additional, Diniz e Magalhães, Caíque Olegário, additional, Henrique Pinto, Samuel, additional, Peixoto, Marco Fabrício Dias, additional, Monteiro-Junior, Renato Sobral, additional, Bourbeau, Kelsey, additional, and Cassilhas, Ricardo Cardoso, additional

Published
2021
Full Text
View/download PDF

31. Indoor aerobic exercise reduces exposure to pollution, improves cognitive function, and enhances BDNF levels in the elderly

Author

Cassilhas, Ricardo Cardoso, primary, De Sousa, Ricardo Augusto Leoni, additional, Caxa, Luciana, additional, Viana, Valter, additional, Meeusen, Romain, additional, Gonçalves, Fábio Luiz, additional, Diniz e Magalhães, Caíque Olegário, additional, Tufik, Sérgio, additional, Dias Peixoto, Marco Fabrício, additional, Monteiro Junior, Renato Sobral, additional, and de Mello, Marco Túlio, additional

Published
2021
Full Text
View/download PDF

32. The Impact of COVID-19 on the Cardiovascular System

Author

Aras Júnior, Roque, Durães, André, Roever, Leonardo, Macedo, Cristiano, Aras, Marcela Gordilho, Nascimento, Luca, Improta-Caria, Alex Cleber, and De Sousa, Ricardo Augusto Leoni

Subjects
Coronavirus, Betacoronavirus, Infection, Cardiovascular System
Abstract

SUMMARY The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus-19 disease (COVID-19), has affected many people in Brazil and worldwide. This disease predominantly affects the organs of the respiratory system, but it also damages the brain, liver, kidneys and especially the heart. In the heart, scientific evidence shows that this virus can damage the coronary arteries, generating microvascular dysfunction, favoring acute myocardial infarction. Furthermore, with the increased expression of pro-inflammatory cytokines, it can lead to myocarditis and cardiac fibrosis, inducing changes in the electrical conduction system of the heart, generating cardiac arrhythmias. All these factors mentioned are protagonists in promoting the increase in the mortality outcome. This outcome may be even higher if the individuals are elderly, or if they have other diseases such as type 2 diabetes mellitus or hypertension, because they may already have cardiomyopathy. In this context, this review focused on the impact that COVID-19 can have on the heart and cardiovascular system and the association of this impact with aging, type 2 diabetes mellitus, cardiac arrhythmias and arterial hypertension

Published
2021

35. MicroRNAs in type 2 diabetes mellitus: potential role of physical exercise.

Author

Cleber Improta-Caria, Alex, Leoni De Sousa, Ricardo Augusto, Roever, Leonardo, Fernandes, Tiago, Menezes de Oliveira, Edilamar, Aras Júnior, Roque, de Freitas Souza, Bruno Solano, Improta-Caria, Alex Cleber, De Sousa, Ricardo Augusto Leoni, Oliveira, Edilamar Menezes de, and Souza, Bruno Solano de Freitas

Abstract

Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disease, and its prevalence has grown worldwide. Several pathophysiological processes contribute to the development, progression and aggravating of the disease, for example, decreased insulin synthesis and secretion, insulin resistance, inflammation, and apoptosis, all these processes are regulated by various epigenetic factors, including microRNAs (miRNAs). MiRNAs are small non-coding RNAs, which are around 20 nucleotides in length and are regulators of gene expression at the post-transcriptional level, have a specific function of inhibiting or degrading a messenger RNA target. Thus, miRNAs modulate the expression of many associated genes with the pathophysiological processes in T2DM. On the other hand, miRNAs are also modulated through physical exercise (PE), which induces a change in their expression pattern during and after exercise. Some scientific evidence shows that PE modulates miRNAs beneficially and improves the signaling pathway of insulin resistance, however, little is known about the function of PE modulating miRNAs associated with the processes of insulin secretion, inflammation, and apoptosis. Thus, the objective of this review is to identify the miRNAs expression pattern in T2DM and compare it with the exercise-induced miRNAs expression pattern, identifying the signaling pathways that these miRNAs are regulating in the processes of insulin secretion, insulin resistance, inflammation, and apoptosis in T2DM, and how PE may have a potential role in modulating these signal transduction pathways, promoting benefits for patients with T2DM. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

36. The Impact of COVID-19 on the Cardiovascular System

Author

Aras Júnior, Roque, primary, Durães, André, additional, Roever, Leonardo, additional, Macedo, Cristiano, additional, Aras, Marcela Gordilho, additional, Nascimento, Luca, additional, Improta-Caria, Alex Cleber, additional, and De Sousa, Ricardo Augusto Leoni, additional

Published
2021
Full Text
View/download PDF

38. Intense Caloric Restriction from Birth Prevents Cardiovascular Aging in Rats

Author

Melo, Dirceu, primary, de Sousa Melo, Dirceu, additional, Pereira, Liliane Costa, additional, Santos, Carina Sousa, additional, Mendes, Bruno Ferreira, additional, Konig, Isaac Filipe Moreira, additional, Queiroz, Ilkilene Pinheiro, additional, Moreno, Lauane Gomes, additional, Cassilhas, Ricardo Cardoso, additional, Esteves, Elizabethe Adriana, additional, Vieira, Etel Rocha, additional, Chaves Garcia, Bruna Caroline, additional, de Castro Magalhães, Flávio, additional, Capettini, Luciano dos Santos Aggum, additional, De Sousa, Ricardo Augusto Leoni, additional, Sampaio, Kinulpe Honorato, additional, and Dias Peixoto, Marco Fabrício, additional

Published
2021
Full Text
View/download PDF

39. Neurological consequences of exercise during prenatal Zika virus exposure to mice pups

Author

De Sousa, Ricardo Augusto Leoni, primary, Peixoto, Marco Fabrício Dias, additional, Leite, Hércules Ribeiro, additional, Oliveira, Lucas Renan Sena de, additional, Freitas, Daniel Almeida, additional, Silva-Júnior, Fidelis Antonio da, additional, Oliveira, Henoque Santos, additional, Rocha-Vieira, Etel, additional, Cassilhas, Ricardo Cardoso, additional, and Oliveira, Danilo Bretas de, additional

Published
2020
Full Text
View/download PDF

40. Does calorie restriction improve cognition?

Author

Dias, Isabella Rocha, primary, Santos, Carina de Sousa, additional, Magalhães, Caíque Olegário Diniz e, additional, de Oliveira, Lucas Renan Sena, additional, Peixoto, Marco Fabrício Dias, additional, De Sousa, Ricardo Augusto Leoni, additional, and Cassilhas, Ricardo Cardoso, additional

Published
2020
Full Text
View/download PDF

42. High-intensity resistance training induces changes in cognitive function, but not in locomotor activity or anxious behavior in rats induced to type 2 diabetes

Author

De Sousa, Ricardo Augusto Leoni, primary, Improta-Caria, Alex Cleber, additional, Jesus-Silva, Francine Menezes de, additional, Magalhães, Caique Olegário Diniz e, additional, Freitas, Daniel Almeida, additional, Lacerda, Ana Cristina Rodrigues, additional, Mendonça, Vanessa Amaral, additional, Cassilhas, Ricardo Cardoso, additional, and Leite, Hércules Ribeiro, additional

Published
2020
Full Text
View/download PDF

44. High-intensity interval training improves cerebellar antioxidant capacity without affecting cognitive functions in rats

Author

Freitas, Daniel Almeida, primary, Rocha-Vieira, Etel, additional, De Sousa, Ricardo Augusto Leoni, additional, Soares, Bruno Alvarenga, additional, Rocha-Gomes, Arthur, additional, Chaves Garcia, Bruna Caroline, additional, Cassilhas, Ricardo Cardoso, additional, Mendonça, Vanessa Amaral, additional, Camargos, Ana Cristina Resende, additional, De Gregorio, José Antonio Michell, additional, Lacerda, Ana Cristina Rodrigues, additional, and Leite, Hércules Ribeiro, additional

Published
2019
Full Text
View/download PDF

45. A single session of high-intensity interval exercise increases antioxidants defenses in the hippocampus of Wistar rats

Author

Melo, Camila S., primary, Rocha-Vieira, Etel, additional, Freitas, Daniel Almeida, additional, Soares, Bruno A., additional, Rocha-Gomes, Arthur, additional, Riul, Tania Regina, additional, Mendonça, Vanessa Amaral, additional, Lacerda, Ana Cristina Rodrigues, additional, Camargos, Ana Cristina Resende, additional, Carvalho, Luciana Estefani Drumond, additional, De Sousa, Ricardo Augusto Leoni, additional, and Leite, Hércules Ribeiro, additional

Published
2019
Full Text
View/download PDF

48. BREVE RELATO DA RESISTÊNCIA À INSULINA E OS BENEFÍCIOS DO EXERCÍCIO RESISTIDO INTENSO NO DIABETES TIPO 2.

Author

De Sousa, Ricardo Augusto Leoni and Pardono, Emerson

Abstract

Diabetes mellitus type 2 (DM2) comprises more than 95% of diabetes cases worldwide. It main characteristic is its resistance to insulin which causes the development of hyperglycemia and hyperinsulinemia. Current study analyzes through a revision of the literature the benefits of resisted exercise in the resistance to insulin and its understanding. The key point in DM2 metabolism and its main causes are the protein kinase B (AKT) and Phosphatidylinositol-3- kinase (PI3-K). Resistance to insulin is associated with defects in the activation of receptors of insulin 1 and 2 and/or low activation of PI3-K and/or the slight displacement of GLUT-4, a transporter of glucose. Its intracellular movement depends on AKT signalization. High intensity RE is capable of promoting a greater phosphorylation of insulin receptors and/or increasing the activity of PI3-K and/or raising the translocation of the main glucose vehicle during physical activity and GLUT-4, by a greater activation of AKT. Intense RE strives against insulin resistance and favors a greater and better functioning of the PI3-K pathway. [ABSTRACT FROM AUTHOR]

Published
2014

49. BREVE RELATO DA DIABETE TIPO II E SUA RELAÇÃO COM O METABOLISMO DE LIPÍDEOS, O EXERCÍCIO RESISTIDO E OS EFEITOS DESTE: QUEBRANDO DOGMAS.

Author

de Sousa, Ricardo Augusto Leoni and Navarro, Francisco

Subjects
PEOPLE with diabetes, LIPID metabolism, RESISTANCE training, STRENGTH training, SYSTEMATIC reviews, DISEASE prevalence
Abstract

Copyright of Revista Brasileira de Prescrição e Fisiologia do Exercício is the property of Instituto Brasileiro de Pesquisa e Ensino em Fisiologia do Exercicio and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2013

50. MicroRNAs regulating signaling pathways in cardiac fibrosis: potential role of the exercise training.

Author

Improta-Caria AC, Rodrigues LF, Joaquim VHA, De Sousa RAL, Fernandes T, and Oliveira EM

Subjects
Humans, Exercise, Signal Transduction, RNA, Messenger genetics, Fibrosis, MicroRNAs genetics, MicroRNAs metabolism, Diabetes Mellitus, Type 2
Abstract

Cardiovascular and metabolic diseases such as hypertension, type 2 diabetes, and obesity develop long-term fibrotic processes in the heart, promoting pathological cardiac remodeling, including after myocardial infarction, reparative fibrotic processes also occur. These processes are regulated by many intracellular signaling pathways that have not yet been completely elucidated, including those associated with microRNA (miRNA) expression. miRNAs are small RNA transcripts (18-25 nucleotides in length) that act as posttranscriptionally regulators of gene expression, inhibiting or degrading one or more target messenger RNAs (mRNAs), and proven to be involved in many biological processes such as cell cycle, differentiation, proliferation, migration, and apoptosis, directly affecting the pathophysiology of several diseases, including cardiac fibrosis. Exercise training can modulate the expression of miRNAs and it is known to be beneficial in various cardiovascular diseases, attenuating cardiac fibrosis processes. However, the signaling pathways modulated by the exercise associated with miRNAs in cardiac fibrosis were not fully understood. Thus, this review aims to analyze the expression of miRNAs that modulate signaling pathways in cardiac fibrosis processes that can be regulated by exercise training.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results