525 results on '"De Strooper B"'
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2. Screening and Characterization Strategies for Nanobodies Targeting Membrane Proteins
3. Missorting of the Dendritic Cell Adhesion Molecule Telencephalin in Presenilin-Deficient Neurons
4. The Putative Role of Presenilins in the Transmembrane Domain Cleavage of Amyloid Precursor Protein and Other Integral Membrane Proteins
5. MEA Neurosensor, the Tool for Synaptic Activity Detection: Acute Amyloid- β Oligomers Synaptotoxicity Study
6. The Parkinson’s gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes
7. Deficiency of Aph1B/C-γ-Secretase Disturbs Nrg1 Cleavage and Sensorimotor Gating That Can Be Reversed with Antipsychotic Treatment
8. Combining In Vitro Cell Biology and In Vivo Mouse Modelling to Study the Mechanisms Underlying Alzheimer’s Disease
9. Melanin Concentrating Hormone- and sleep-dependent synaptic downscaling is impaired in Alzheimer’s Disease
10. The pathobiology of the secretases in Alzheimer disease
11. The Parkinsonʼs gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes
12. Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9)
13. Reactive astrocyte nomenclature, definitions, and future directions
14. Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain
15. The deubiquitinase USP15 antagonizes parkin-mediated mitochondrial ubiquitination and mitophagy: 18
16. Deficiency of Aph1B/C-[gamma]-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment
17. Mixing Aβ(1-40) and Aβ(1-42) peptides generates unique amyloid fibrils
18. Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP
19. MEA Neurosensor, the Tool for Synaptic Activity Detection: Acute Amyloid- β Oligomers Synaptotoxicity Study
20. A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes: P24-2
21. The function of presenilin-1 in amyloid β-peptide generation and brain development
22. PARKINSONʼS DISEASE: PINK1 AND MITOCHONDRIAL COMPLEX I FUNCTION: S09-03
23. From Alzheimerʼs disease and other dementias to basic mechanisms of neurodegeneration: Theme III. 1
24. Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils
25. Missorting of the Dendritic Cell Adhesion Molecule Telencephalin in Presenilin-Deficient Neurons
26. Alzheimer Dementia Caused by a Novel Mutation Located in the APP C-Terminal Intracytosolic Fragment
27. The Putative Role of Presenilins in the Transmembrane Domain Cleavage of Amyloid Precursor Protein and Other Integral Membrane Proteins
28. Downregulation of PS1 expression in neurons decreases beta-amyloid production: a biochemical link between the two major familial Alzheimer's disease genes
29. Combining In Vitro Cell Biology and In Vivo Mouse Modelling to Study the Mechanisms Underlying Alzheimer’s Disease
30. Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP
31. PF159 COMBINATION OF SELECTIVE GAMMA-SECRETASE INHIBITOR MRK-560 WITH OTHER TARGETED THERAPY IS AN EFFECTIVE AND SAFE TREATMENT FOR T-ALL
32. PS917 SAFE TARGETING OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA BY SUBUNIT SELECTIVE GAMMA-SECRETASE INHIBITION
33. BIOLOGY AND GENETICS OF THE PRESENILIN PROTEINS ASSOCIATED WITH ALZHEIMER DISEASEB
34. Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease
35. Fibronectin-Mediated Cellular (Inter)Actions
36. Qualitative changes in human ?-secretase underlie familial Alzheimer's disease
37. Close encounter: mitochondria, endoplasmic reticulum and Alzheimer's disease
38. Celbiologische studie van de ziekte van Alzheimer
39. Molecular plasticity regulates oligomerization and cytotoxicity of the multi-peptide length Abeta pool
40. Effect of ApoE isoform and lipidation status on proteolytic clearance of Amyloid-beta peptide
41. Modification of gamma-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease
42. Risk factor for Alzheimers's disease: Pathological ABETA 40/42 ratio facilitates formation of stable neurotoxic oligomers
43. Biophysical consideration of gamma secretase modulation as potential target for Alzheimer's disease. Consequences of amyloid-beta peptide lenght variation
44. The World of Dementia Beyond 2020
45. ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase
46. European Alzheimer disease funding
47. The Parkinson’s gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes
48. A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch1 and APP proteolysis
49. Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease
50. Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions
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