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441 results on '"DeBiasi, Roberta L"'

1. Building a growing genomic repository for maternal and fetal health through the PING Consortium

Author

Abdelmalek, Clara M., Singh, Shriya, Fasil, Blain, Horvath, Allison R., Mulkey, Sarah B., Curé, Carlos, Campos, Maribel, Cavalcanti, Denise P., Tong, Van T., Mercado, Marcela, Daza, Marcela, Benavides, Mónica Marcela, Acosta, Jacqueline, Gilboa, Suzanne, Valencia, Diana, Sancken, Christina L., Newton, Suzanne, Scalabrin, Deolinda M. F., Mussi-Pinhata, Marisa M., Vasconcelos, Zilton, Chakhtoura, Nahida, Moye, Jack, Leslie, Elizabeth J., Bulas, Dorothy, Vezina, Gilbert, Marques, Fernanda J. P., Leyser, Marcio, Del Campo, Miguel, Vilain, Eric, DeBiasi, Roberta L., Wang, Tongguang, Nath, Avindra, Haydar, Tarik, Muenke, Max, Mansour, Tamer A., du Plessis, Adre J., Murray, Jeffrey C., Cordero, José F., and Kousa, Youssef A.

Published
2025
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2. Pediatric SARS-CoV-2 long term outcomes study (PECOS): cross sectional analysis at baseline

Author

Montealegre Sanchez, Gina A., Arrigoni, Lauren E., Yonts, Alexandra B., Rubenstein, Kevin B., Bost, James E., Wolff, Max T., Barrix, Mallory C., Bandettini, W. Patricia, Boateng, Bema, Bulas, Dorothy I., Burklow, Thomas R., Carlyle, Kayla P., Chen, Marcus, Das, Sanchita, Dewar, Robin L., Dixon, Austin A., Edu, Maureen A., Falik, Rachel L., Geslak, Monika L., Gierdalski, Marcin, Harahsheh, Ashraf S., Herbert, Linda J., Highbarger, Jeroen, Huq, Saira R., Ko, Arthur, Koumbourlis, Anastassios C., Lacey, Stephanie R., Lipton, Andrew J., Monaghan, Maureen, Ndour, Anta S., Olivieri, Laura J., Pillai, Dinesh K., Rehm, Catherine A., Sable, Craig A., Sachdev, Vandana, Thurm, Audrey E., Truong, Uyen T., Turkbey, Evrim B., Vilain, Eric, Weyers, Shera, White, Jacob S., Williams, Abigail A., Zember, Jonathan, Liang, C. Jason, Delaney, Meghan, Batshaw, Mark L., Notarangelo, Luigi D., Wessel, David L., Barron, Karyl, and DeBiasi, Roberta L.

Published
2024
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4. Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C

Author

Loy, Conor J, Sotomayor-Gonzalez, Alicia, Servellita, Venice, Nguyen, Jenny, Lenz, Joan, Bhattacharya, Sanchita, Williams, Meagan E, Cheng, Alexandre P, Bliss, Andrew, Saldhi, Prachi, Brazer, Noah, Streithorst, Jessica, Suslovic, William, Hsieh, Charlotte J, Bahar, Burak, Wood, Nathan, Foresythe, Abiodun, Gliwa, Amelia, Bhakta, Kushmita, Perez, Maria A, Hussaini, Laila, Anderson, Evan J, Chahroudi, Ann, Delaney, Meghan, Butte, Atul J, DeBiasi, Roberta L, Rostad, Christina A, De Vlaminck, Iwijn, and Chiu, Charles Y

Subjects
Pediatric, Genetics, Rare Diseases, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, 4.1 Discovery and preclinical testing of markers and technologies, Detection, screening and diagnosis, Inflammatory and immune system, Good Health and Well Being, Humans, Child, Nucleic Acids, COVID-19, RNA, Cell-Free Nucleic Acids, Biomarkers, DNA damage, RNA sequencing, RNA-seq, SARS-CoV-2, bisulfite sequencing, cell damage, cell-free DNA, cell-free RNA, clinical severity, coronavirus disease 2019, disease biomarkers, host response, immune response, multisystem inflammatory syndrome in children, nucleic acid sequencing, pediatric, signaling pathways, systems biology, tissue damage, whole-blood RNA
Abstract

Differential host responses in coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) remain poorly characterized. Here, we use next-generation sequencing to longitudinally analyze blood samples from pediatric patients with COVID-19 or MIS-C across three hospitals. Profiling of plasma cell-free nucleic acids uncovers distinct signatures of cell injury and death between COVID-19 and MIS-C, with increased multiorgan involvement in MIS-C encompassing diverse cell types, including endothelial and neuronal cells, and an enrichment of pyroptosis-related genes. Whole-blood RNA profiling reveals upregulation of similar pro-inflammatory pathways in COVID-19 and MIS-C but also MIS-C-specific downregulation of T cell-associated pathways. Profiling of plasma cell-free RNA and whole-blood RNA in paired samples yields different but complementary signatures for each disease state. Our work provides a systems-level view of immune responses and tissue damage in COVID-19 and MIS-C and informs future development of new disease biomarkers.

Published
2023

5. Outcomes up to age 36 months after congenital Zika virus infection—U.S. states

Author

Neelam, Varsha, Woodworth, Kate R., Chang, Daniel J., Roth, Nicole M., Reynolds, Megan R., Akosa, Amanda, Carr, Christopher P., Anderson, Kayla N., Mulkey, Sarah B., DeBiasi, Roberta L., Biddle, Cara, Lee, Ellen H., Elmore, Amanda L., Scotland, Sarah J., Sowunmi, Similoluwa, Longcore, Nicole D., Ahmed, Muhammad, Langlois, Peter H., Khuwaja, Salma, Browne, Shea Elizabeth, Lind, Leah, Shim, Kyoo, Gosciminski, Michael, Blumenfeld, Rachel, Khuntia, Shreya, Halai, Umme-Aiman, Locklear, Autumn, Chan, Mary, Willabus, Teri’, Tonzel, Julius, Marzec, Natalie S., Barreto, Nianest Alers, Sanchez, Connie, Fornoff, Jane, Hale, Shelby, Nance, Amy, Iguchi, Lisa, Adibhatla, Sowmya N., Potts, Emily, Schiffman, Elizabeth, Raman, Devin, McDonald, Morgan F., Stricklin, Brandi, Ludwig, Elizabeth, Denson, Lindsay, Contreras, Dianna, Romitti, Paul A., Ferrell, Emily, Marx, Meghan, Signs, Kimberly, Cook, Amie, Leedom, Vinita Oberoi, Beauregard, Suzann, Orantes, Lucia C., Cronquist, Laura, Roush, Lesley, Godfred-Cato, Shana, Gilboa, Suzanne M., Meaney-Delman, Dana, Honein, Margaret A., Moore, Cynthia A., and Tong, Van T.

Published
2024
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8. A machine-learning algorithm for diagnosis of multisystem inflammatory syndrome in children and Kawasaki disease in the USA: a retrospective model development and validation study

Author

Lam, Jonathan Y, Shimizu, Chisato, Tremoulet, Adriana H, Bainto, Emelia, Roberts, Samantha C, Sivilay, Nipha, Gardiner, Michael A, Kanegaye, John T, Hogan, Alexander H, Salazar, Juan C, Mohandas, Sindhu, Szmuszkovicz, Jacqueline R, Mahanta, Simran, Dionne, Audrey, Newburger, Jane W, Ansusinha, Emily, DeBiasi, Roberta L, Hao, Shiying, Ling, Xuefeng B, Cohen, Harvey J, Nemati, Shamim, Burns, Jane C, Group, Pediatric Emergency Medicine Kawasaki Disease Research, Abe, Naomi, Austin-Page, Lukas R, Bryl, Amy W, Donofrio-Odmann, J Joelle, Ekpenyong, Atim, Gutglass, David J, Nguyen, Margaret B, Schwartz, Kristy, Ulrich, Stacey, Vayngortin, Tatyana, Zimmerman, Elise, Group, CHARMS Study, Anderson, Marsha, Ang, Jocelyn Y, Ashouri, Negar, Bocchini, Joseph, D'Addese, Laura, Dominguez, Samuel, Gutierrez, Maria Pila, Harahsheh, Ashraf S, Hite, Michelle, Jone, Pei-Ni, Kumar, Madan, Manaloor, John J, Melish, Marian, Morgan, Lerraughn, Natale, JoAnne E, Rometo, Allison, Rosenkranz, Margalit, Rowley, Anne H, Samuy, Nichole, Scalici, Paul, and Sykes, Michelle

Subjects
Health Services and Systems, Health Sciences, Networking and Information Technology R&D (NITRD), Emerging Infectious Diseases, Pediatric, Infectious Diseases, Machine Learning and Artificial Intelligence, Clinical Research, Prevention, Rare Diseases, Algorithms, Artificial Intelligence, COVID-19, COVID-19 Testing, Child, Humans, Machine Learning, Mucocutaneous Lymph Node Syndrome, Pandemics, Retrospective Studies, SARS-CoV-2, Systemic Inflammatory Response Syndrome, United States, Pediatric Emergency Medicine Kawasaki Disease Research Group, CHARMS Study Group, Health services and systems
Abstract

BackgroundMultisystem inflammatory syndrome in children (MIS-C) is a novel disease that was identified during the COVID-19 pandemic and is characterised by systemic inflammation following SARS-CoV-2 infection. Early detection of MIS-C is a challenge given its clinical similarities to Kawasaki disease and other acute febrile childhood illnesses. We aimed to develop and validate an artificial intelligence algorithm that can distinguish among MIS-C, Kawasaki disease, and other similar febrile illnesses and aid in the diagnosis of patients in the emergency department and acute care setting.MethodsIn this retrospective model development and validation study, we developed a deep-learning algorithm called KIDMATCH (Kawasaki Disease vs Multisystem Inflammatory Syndrome in Children) using patient age, the five classic clinical Kawasaki disease signs, and 17 laboratory measurements. All features were prospectively collected at the time of initial evaluation from patients diagnosed with Kawasaki disease or other febrile illness between Jan 1, 2009, and Dec 31, 2019, at Rady Children's Hospital in San Diego (CA, USA). For patients with MIS-C, the same data were collected from patients between May 7, 2020, and July 20, 2021, at Rady Children's Hospital, Connecticut Children's Medical Center in Hartford (CT, USA), and Children's Hospital Los Angeles (CA, USA). We trained a two-stage model consisting of feedforward neural networks to distinguish between patients with MIS-C and those without and then those with Kawasaki disease and other febrile illnesses. After internally validating the algorithm using stratified tenfold cross-validation, we incorporated a conformal prediction framework to tag patients with erroneous data or distribution shifts. We finally externally validated KIDMATCH on patients with MIS-C enrolled between April 22, 2020, and July 21, 2021, from Boston Children's Hospital (MA, USA), Children's National Hospital (Washington, DC, USA), and the CHARMS Study Group consortium of 14 US hospitals.Findings1517 patients diagnosed at Rady Children's Hospital between Jan 1, 2009, and June 7, 2021, with MIS-C (n=69), Kawasaki disease (n=775), or other febrile illnesses (n=673) were identified for internal validation, with an additional 16 patients with MIS-C included from Connecticut Children's Medical Center and 50 from Children's Hospital Los Angeles between May 7, 2020, and July 20, 2021. KIDMATCH achieved a median area under the receiver operating characteristic curve during internal validation of 98·8% (IQR 98·0-99·3) in the first stage and 96·0% (95·6-97·2) in the second stage. We externally validated KIDMATCH on 175 patients with MIS-C from Boston Children's Hospital (n=50), Children's National Hospital (n=42), and the CHARMS Study Group consortium of 14 US hospitals (n=83). External validation of KIDMATCH on patients with MIS-C correctly classified 76 of 81 patients (94% accuracy, two rejected by conformal prediction) from 14 hospitals in the CHARMS Study Group consortium, 47 of 49 patients (96% accuracy, one rejected by conformal prediction) from Boston Children's Hospital, and 36 of 40 patients (90% accuracy, two rejected by conformal prediction) from Children's National Hospital.InterpretationKIDMATCH has the potential to aid front-line clinicians to distinguish between MIS-C, Kawasaki disease, and other similar febrile illnesses to allow prompt treatment and prevent severe complications.FundingUS Eunice Kennedy Shriver National Institute of Child Health and Human Development, US National Heart, Lung, and Blood Institute, US Patient-Centered Outcomes Research Institute, US National Library of Medicine, the McCance Foundation, and the Gordon and Marilyn Macklin Foundation.

Published
2022

9. Oral Valganciclovir Initiated Beyond 1 Month of Age as Treatment of Sensorineural Hearing Loss Caused by Congenital Cytomegalovirus Infection: A Randomized Clinical Trial

Author

Kimberlin, David W., Aban, Inmaculada, Peri, Kalyani, Nishikawa, Javier K., Bernatoniene, Jolanta, Emonts, Marieke, Klein, Nigel, Bamford, Alasdair, DeBiasi, Roberta L., Faust, Saul N., Jones, Christine E., McMaster, Paddy, Caserta, Mary, Ahmed, Amina, Sharland, Mike, Demmler-Harrison, Gail, Hackett, Scott, Sánchez, Pablo J., Shackley, Fiona, Kelly, Dominic, Dennehy, Penelope H., Storch, Gregory A., Whitley, Richard J., and Griffiths, Paul

Published
2024
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10. Temporal clustering of Kawasaki disease cases around the world.

Author

Burney, Jennifer A, DeHaan, Laurel L, Shimizu, Chisato, Bainto, Emelia V, Newburger, Jane W, DeBiasi, Roberta L, Dominguez, Samuel R, Portman, Michael A, Melish, Marian, Bratincsak, Andras, Fabi, Marianna, Corinaldesi, Elena, Yu, Jeong Jin, Gee, Paul, Kitano, Naomi, Tremoulet, Adriana H, Cayan, Daniel R, Burns, Jane C, and Kawasaki Disease Climate Study Group

Subjects
Kawasaki Disease Climate Study Group, Humans, Mucocutaneous Lymph Node Syndrome, Incidence, Cluster Analysis, Linear Models, Monte Carlo Method, Time Factors, Child, Hospitals, United States, Italy, New Zealand, Republic of Korea, Global Health
Abstract

In a single-site study (San Diego, CA, USA), we previously showed that Kawasaki Disease (KD) cases cluster temporally in bursts of approximately 7 days. These clusters occurred more often than would be expected at random even after accounting for long-term trends and seasonality. This finding raised the question of whether other locations around the world experience similar temporal clusters of KD that might offer clues to disease etiology. Here we combine data from San Diego and nine additional sites around the world with hospitals that care for large numbers of KD patients, as well as two multi-hospital catchment regions. We found that across these sites, KD cases clustered at short time scales and there were anomalously long quiet periods with no cases. Both of these phenomena occurred more often than would be expected given local trends and seasonality. Additionally, we found unusually frequent temporal overlaps of KD clusters and quiet periods between pairs of sites. These findings suggest that regional and planetary range environmental influences create periods of higher or lower exposure to KD triggers that may offer clues to the etiology of KD.

Published
2021

15. Characteristics and Clinical Outcomes of Children and Adolescents Aged

Author

Wanga, Valentine, Gerdes, Megan E., Shi, Dallas S., Choudhary, Rewa, Dulski, Theresa M., Hsu, Sophia, Idubor, Osatohamwen I., Webber, Bryant J., Wendel, Arthur M., Agathis, Nickolas T., Anderson, Kristi, Boyles, Tricia, Chiu, Sophia K., Click, Eleanor S., Da Silva, Juliana, Dupont, Hannah, Evans, Mary, Gold, Jeremy A.W., Haston, Julia, Logan, Pamela, Maloney, Susan A., Martinez, Marisol, Natarajan, Pavithra, Spicer, Kevin B., Swancutt, Mark, Stevens, Valerie A., Brown, Jessica, Chandra, Gyan, Light, Megan, Barr, Frederick E., Snowden, Jessica, Kociolek, Larry K., McHugh, Matthew, Wessel, David, Simpson, Joelle N., Gorman, Kathleen C., Breslin, Kristen A., DeBiasi, Roberta L., Thompson, Aaron, Kline, Mark W., Bloom, Julie A., Singh, Ila R., Dowlin, Michael, Wietecha, Mark, Schweitzer, Beth, Morris, Sapna Bamrah, Koumans, Emily H., Ko, Jean Y., Kimball, Anne A., and Siegel, David A.

Published
2021

16. Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis

Author

Wilson, Michael R, Sample, Hannah A, Zorn, Kelsey C, Arevalo, Shaun, Yu, Guixia, Neuhaus, John, Federman, Scot, Stryke, Doug, Briggs, Benjamin, Langelier, Charles, Berger, Amy, Douglas, Vanja, Josephson, S Andrew, Chow, Felicia C, Fulton, Brent D, DeRisi, Joseph L, Gelfand, Jeffrey M, Naccache, Samia N, Bender, Jeffrey, Dien Bard, Jennifer, Murkey, Jamie, Carlson, Magrit, Vespa, Paul M, Vijayan, Tara, Allyn, Paul R, Campeau, Shelley, Humphries, Romney M, Klausner, Jeffrey D, Ganzon, Czarina D, Memar, Fatemeh, Ocampo, Nicolle A, Zimmermann, Lara L, Cohen, Stuart H, Polage, Christopher R, DeBiasi, Roberta L, Haller, Barbara, Dallas, Ronald, Maron, Gabriela, Hayden, Randall, Messacar, Kevin, Dominguez, Samuel R, Miller, Steve, and Chiu, Charles Y

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Rare Diseases, Biotechnology, Infectious Diseases, Neurosciences, Brain Disorders, Clinical Research, 4.2 Evaluation of markers and technologies, Infection, Good Health and Well Being, Adolescent, Adult, Cerebrospinal Fluid, Child, Child, Preschool, Encephalitis, Female, Genome, Microbial, High-Throughput Nucleotide Sequencing, Humans, Infant, Infections, Length of Stay, Male, Meningitis, Meningoencephalitis, Metagenomics, Middle Aged, Myelitis, Prospective Studies, Sequence Analysis, DNA, Sequence Analysis, RNA, Young Adult, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundMetagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF) has the potential to identify a broad range of pathogens in a single test.MethodsIn a 1-year, multicenter, prospective study, we investigated the usefulness of metagenomic NGS of CSF for the diagnosis of infectious meningitis and encephalitis in hospitalized patients. All positive tests for pathogens on metagenomic NGS were confirmed by orthogonal laboratory testing. Physician feedback was elicited by teleconferences with a clinical microbial sequencing board and by surveys. Clinical effect was evaluated by retrospective chart review.ResultsWe enrolled 204 pediatric and adult patients at eight hospitals. Patients were severely ill: 48.5% had been admitted to the intensive care unit, and the 30-day mortality among all study patients was 11.3%. A total of 58 infections of the nervous system were diagnosed in 57 patients (27.9%). Among these 58 infections, metagenomic NGS identified 13 (22%) that were not identified by clinical testing at the source hospital. Among the remaining 45 infections (78%), metagenomic NGS made concurrent diagnoses in 19. Of the 26 infections not identified by metagenomic NGS, 11 were diagnosed by serologic testing only, 7 were diagnosed from tissue samples other than CSF, and 8 were negative on metagenomic NGS owing to low titers of pathogens in CSF. A total of 8 of 13 diagnoses made solely by metagenomic NGS had a likely clinical effect, with 7 of 13 guiding treatment.ConclusionsRoutine microbiologic testing is often insufficient to detect all neuroinvasive pathogens. In this study, metagenomic NGS of CSF obtained from patients with meningitis or encephalitis improved diagnosis of neurologic infections and provided actionable information in some cases. (Funded by the National Institutes of Health and others; PDAID ClinicalTrials.gov number, NCT02910037.).

Published
2019

17. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis.

Author

Messacar, Kevin, Sillau, Stefan, Hopkins, Sarah E, Otten, Catherine, Wilson-Murphy, Molly, Wong, Brian, Santoro, Jonathan D, Treister, Andrew, Bains, Harlori K, Torres, Alcy, Zabrocki, Luke, Glanternik, Julia R, Hurst, Amanda L, Martin, Jan A, Schreiner, Teri, Makhani, Naila, DeBiasi, Roberta L, Kruer, Michael C, Tremoulet, Adriana H, Van Haren, Keith, Desai, Jay, Benson, Leslie A, Gorman, Mark P, Abzug, Mark J, Tyler, Kenneth L, and Dominguez, Samuel R

Subjects
Humans, Central Nervous System Viral Diseases, Myelitis, Neuromuscular Diseases, Fluoxetine, Antiviral Agents, Treatment Outcome, Retrospective Studies, Child, Child, Preschool, Female, Male, Neurosciences, Brain Disorders, Patient Safety, Clinical Research, Clinical Sciences, Cognitive Sciences, Neurology & Neurosurgery
Abstract

ObjectiveTo determine the safety, tolerability, and efficacy of fluoxetine for proven or presumptive enterovirus (EV) D68-associated acute flaccid myelitis (AFM).MethodsA multicenter cohort study of US patients with AFM in 2015-2016 compared serious adverse events (SAEs), adverse effects, and outcomes between fluoxetine-treated patients and untreated controls. Fluoxetine was administered at the discretion of treating providers with data gathered retrospectively. The primary outcome was change in summative limb strength score (SLSS; sum of Medical Research Council strength in all 4 limbs, ranging from 20 [normal strength] to 0 [complete quadriparesis]) between initial examination and latest follow-up, with increased SLSS reflecting improvement and decreased SLSS reflecting worsened strength.ResultsFifty-six patients with AFM from 12 centers met study criteria. Among 30 patients exposed to fluoxetine, no SAEs were reported and adverse effect rates were similar to unexposed patients (47% vs 65%, p = 0.16). The 28 patients treated with >1 dose of fluoxetine were more likely to have EV-D68 identified (57.1% vs 14.3%, p < 0.001). Their SLSS was similar at initial examination (mean SLSS 12.9 vs 14.3, p = 0.31) but lower at nadir (mean SLSS 9.25 vs 12.82, p = 0.02) and latest follow-up (mean SLSS 12.5 vs 16.4, p = 0.005) compared with the 28 patients receiving 1 (n = 2) or no (n = 26) doses. In propensity-adjusted analysis, SLSS from initial examination to latest follow-up decreased by 0.2 (95% confidence interval [CI] -1.8 to +1.4) in fluoxetine-treated patients and increased by 2.5 (95% CI +0.7 to +4.4) in untreated patients (p = 0.015).ConclusionFluoxetine was well-tolerated. Fluoxetine was preferentially given to patients with AFM with EV-D68 identified and more severe paralysis at nadir, who ultimately had poorer long-term outcomes.Classification of evidenceThis study provides Class IV evidence that for patients with EV-D68-associated AFM, fluoxetine is well-tolerated and not associated with improved neurologic outcomes.

Published
2019

18. A machine-learning algorithm for diagnosis of multisystem inflammatory syndrome in children and Kawasaki disease in the USA: a retrospective model development and validation study

Author

Abe, Naomi, Austin-Page, Lukas R., Bryl, Amy W., Donofrio-Odmann, J Joelle, Ekpenyong, Atim, Gutglass, David J., Nguyen, Margaret B., Schwartz, Kristy, Ulrich, Stacey, Vayngortin, Tatyana, Zimmerman, Elise, Anderson, Marsha, Ang, Jocelyn Y., Ashouri, Negar, Bocchini, Joseph, D'Addese, Laura, Dominguez, Samuel, Gutierrez, Maria Pila, Harahsheh, Ashraf S., Hite, Michelle, Jone, Pei-Ni, Kumar, Madan, Manaloor, John J., Melish, Marian, Morgan, Lerraughn, Natale, JoAnne E., Rometo, Allison, Rosenkranz, Margalit, Rowley, Anne H., Samuy, Nichole, Scalici, Paul, Sykes, Michelle, Lam, Jonathan Y, Shimizu, Chisato, Tremoulet, Adriana H, Bainto, Emelia, Roberts, Samantha C, Sivilay, Nipha, Gardiner, Michael A, Kanegaye, John T, Hogan, Alexander H, Salazar, Juan C, Mohandas, Sindhu, Szmuszkovicz, Jacqueline R, Mahanta, Simran, Dionne, Audrey, Newburger, Jane W, Ansusinha, Emily, DeBiasi, Roberta L, Hao, Shiying, Ling, Xuefeng B, Cohen, Harvey J, Nemati, Shamim, and Burns, Jane C

Published
2022
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19. Examining Infant and Child Neurodevelopmental Outcomes After Lyme Disease During Pregnancy.

Author

Williams, Meagan E., Schwartz, David A., DeBiasi, Roberta L., and Mulkey, Sarah B.

Subjects
LYME disease, TICK-borne diseases, CONGENITAL disorders, VECTOR-borne diseases, SYMPTOMS, CHILD development
Abstract

Lyme disease is the most common vector-borne disease in the United States. Recent environmental and socioecological changes have led to an increased incidence of Lyme and other tick-borne diseases, which enhances the urgency of identifying and mitigating adverse outcomes of Lyme disease exposure. Lyme disease during pregnancy, especially when untreated, may lead to adverse pregnancy and neonatal outcomes; however, long-term child outcomes following utero exposure to Lyme disease have not yet been systematically assessed. This concise review describes the current state of knowledge of Lyme disease as a congenital infection and the potential effects of in utero exposure to Lyme disease infection on the neurodevelopment of infants and children. We highlight the importance of distinguishing between acute Lyme disease and a chronic condition termed Post-Treatment Lyme Disease Syndrome, as the impacts of both conditions on the developing fetus and subsequent child development may differ. The importance of placental pathology for patients with acute or chronic symptoms of Lyme disease in pregnancy is explored. Future research aiming to understand and protect neurodevelopment after antenatal Lyme disease must carefully collect potentially confounding variables such as symptomatology and treatment, use clear and standard case definitions, and follow children into school-age and beyond. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Pediatric urinary tract infections caused by poultry-associated Escherichia coli

Author

Aziz, Maliha, primary, Davis, Gregg S., additional, Park, Daniel E., additional, Idris, Azza H., additional, Sariya, Sanjeev, additional, Wang, Yashan, additional, Zerbonne, Sarah, additional, Nordstrom, Lora, additional, Weaver, Brett, additional, Statham, Sally, additional, Johnson, Timothy J., additional, Campos, Joseph, additional, Castro-Nallar, Eduardo, additional, Crandall, Keith A., additional, Wu, Zhenke, additional, Liu, Cindy M., additional, DeBiasi, Roberta L., additional, and Price, Lance B., additional

Published
2024
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21. Building a growing genomic data repository for maternal and fetal health through the PING Consortium

Author

Abdelmalek, Clara, primary, Fasil, Blain, additional, Singh, Shriya, additional, Horvath, Allison, additional, Mulkey, Sarah, additional, Cure, Carlos, additional, Campos, Maribel, additional, Cavalcanti, Denise, additional, Tong, Van, additional, Maria Mercado Reyes, Marcela, additional, Daza, Marcela, additional, Marcela Benavides Ruiz, Monica, additional, Acosta, Jacqueline, additional, Gilboa, Suzanne, additional, Valencia, Diana, additional, Sancken, Christina, additional, Newton, Suzanne, additional, Scalabrin, Deolinda, additional, Mussi-Pinhata, Marisa, additional, Vasconcelos, Zilton, additional, Chakhtoura, Nahida, additional, Moye, Jack, additional, Leslie, Elizabeth, additional, Bulas, Dorothy, additional, Vezina, Gilbert, additional, Marques, Fernanda, additional, Leyser, Marcio, additional, Del Campo, Miguel, additional, Vilain, Eric, additional, Wang, Tongguang, additional, Nath, Avindra, additional, Haydar, Tarik, additional, Muenke, Max, additional, Mansour, Tamer A, additional, du Plessis, Adre, additional, DeBiasi, Roberta L, additional, Murray, Jeffrey C., additional, Cordero, Jose F, additional, and Kousa, Youssef, additional

Published
2024
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22. Common genetic susceptibility loci link PFAPA syndrome, Behçet’s disease, and recurrent aphthous stomatitis

Author

The Genomic Ascertainment Cohort, Manthiram, Kalpana, Preite, Silvia, Dedeoglu, Fatma, Demir, Selcan, Ozen, Seza, Edwards, Kathryn M., Lapidus, Sivia, Katz, Alexander E., Feder, Henry M., Lawton, Maranda, Licameli, Greg R., Wright, Peter F., Le, Julie, Barron, Karyl S., Ombrello, Amanda K., Barham, Beverly, Romeo, Tina, Jones, Anne, Srinivasalu, Hemalatha, Mudd, Pamela A., DeBiasi, Roberta L., Gül, Ahmet, Marshall, Gary S., Jones, Olcay Y., Chandrasekharappa, Settara C., Stepanovskiy, Yuriy, Ferguson, Polly J., Schwartzberg, Pamela L., Remmers, Elaine F., and Kastner, Daniel L.

Published
2020

23. Multisystem Inflammatory Syndrome of Children: Subphenotypes, Risk Factors, Biomarkers, Cytokine Profiles, and Viral Sequencing

Author

Diab, Yasser, Herstek, Jessica, Sehgal, Sona, Sharma, Hemant, Hahn, Andrea, Harik, Nada, Hamdy, Rana, Hanisch, Benjamin, Jantausch, Barbara, Koay, Adeline, Wiedermann, Bernhard, Yonts, Alexandra, Song, Xiaoyan, Dien Bard, Jennifer, DeBiasi, Roberta L., Harahsheh, Ashraf S., Srinivasalu, Hemalatha, Krishnan, Anita, Sharron, Matthew P., Parikh, Kavita, Smith, Karen, Bell, Michael, Michael, Drew, Delaney, Meghan, Campos, Joseph, Vilain, Eric, LoTempio, Jonathan, Kline, Jaclyn N., Ronis, Tova, Majumdar, Suvankar, Sadler, Eleanor, Conway, Susan R., Berul, Charles I., Sule, Sangeeta, Lahoz, Rebeca, Ansusinha, Emily, Pershad, Jay, Bundy, Vanessa, Wells, Elizabeth, Bost, James E., and Wessel, David

Published
2021
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24. Plasma cell-free RNA signatures of inflammatory syndromes in children.

Author

Loy, Conor J., Servellita, Venice, Sotomayor-Gonzalez, Alicia, Bliss, Andrew, Lenz, Joan S., Belcher, Emma, Suslovic, Will, Nguyen, Jenny, Williams, Meagan E., Oseguera, Miriam, Gardiner, Michael A., Jong-Ha Choi, Hui-Mien Hsiao, Hao Wang, Jihoon Kim, Chisato Shimizu, Tremoulet, Adriana H., Delaney, Meghan, DeBiasi, Roberta L., and Rostad, Christina A.

Subjects
MULTISYSTEM inflammatory syndrome in children, MACHINE learning, SYNDROMES in children, BACTERIAL diseases, MUCOCUTANEOUS lymph node syndrome
Abstract

Inflammatory syndromes, including those caused by infection, are a major cause of hospital admissions among children and are often misdiagnosed because of a lack of advanced molecular diagnostic tools. In this study, we explored the utility of circulating cell-free RNA (cfRNA) in plasma as an analyte for the differential diagnosis and characterization of pediatric inflammatory syndromes. We profiled cfRNA in 370 plasma samples from pediatric patients with a range of inflammatory conditions, including Kawasaki disease (KD), multisystem inflammatory syndrome in children (MIS-C), viral infections, and bacterial infections. We developed machine learning models based on these cfRNA profiles, which effectively differentiated KD from MIS-C--two conditions presenting with overlapping symptoms--with high performance [test area under the curve = 0.98]. We further extended this methodology into a multiclass machine learning framework that achieved 80% accuracy in distinguishing among KD, MIS-C, viral, and bacterial infections. We further demonstrated that cfRNA profiles can be used to quantify injury to specific tissues and organs, including the liver, heart, endothelium, nervous system, and the upper respiratory tract. Overall, this study identified cfRNA as a versatile analyte for the differential diagnosis and characterization of a wide range of pediatric inflammatory syndromes. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Neurodevelopmental Outcomes of Preschoolers with Antenatal Zika Virus Exposure Born in the United States.

Author

Mulkey, Sarah B., Corn, Elizabeth, Williams, Meagan E., Ansusinha, Emily, Podolsky, Robert H., Arroyave-Wessel, Margarita, Vezina, Gilbert, Peyton, Colleen, Msall, Michael E., and DeBiasi, Roberta L.

Subjects
ZIKA virus infections, CHILDREN with autism spectrum disorders, SCHOOL children, READINESS for school, CONGENITAL disorders, PERFORMANCE in children
Abstract

Neurodevelopmental outcomes for preschool-age children in the United States with in utero Zika virus (ZIKV) exposure have not yet been reported. We performed a case-control study to assess whether children exposed in utero to ZIKV have abnormal neurodevelopment at age 4–5 years compared to unexposed controls. Thirteen ZIKV-exposed cases that did not have microcephaly or other specific features of congenital Zika syndrome and 12 controls were evaluated between ages 4–5 years. Child neurodevelopment was assessed using the Pediatric Evaluation of Disability Inventory, Behavior Rating Inventory of Executive Function, Peabody Picture Vocabulary Test, Bracken School Readiness Assessment (BSRA), and Movement Assessment Battery for Children (MABC). Caregivers answered questions on the child's medical history and family demographics. Cases and controls were evaluated at mean (SD) ages 4.9 (0.3) and 4.8 (0.4) years, respectively. Caregivers reported more behavior and mood problems in cases than controls. MABC scores showed more gross and fine motor coordination difficulties among cases than controls. Controls trended towards higher performance on concepts underlying school readiness on BSRA. Three cases had a diagnosis of autism spectrum disorder or global developmental delay. Continued follow-up through school age for children with prenatal ZIKV exposure is needed to understand the impact of in utero ZIKV exposure on motor coordination, cognition, executive function, and academic achievement. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Reply to Correspondence

Author

Monaghan, Maureen, primary, Norman, Stephanie, additional, Gierdalski, Marcin, additional, Marques, Adriana, additional, Bost, James E., additional, and DeBiasi, Roberta L., additional

Published
2023
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34. Outcomes up to age 36 months after congenital Zika virus infection—U.S. states

Author

Neelam, Varsha, primary, Woodworth, Kate R., additional, Chang, Daniel J., additional, Roth, Nicole M., additional, Reynolds, Megan R., additional, Akosa, Amanda, additional, Carr, Christopher P., additional, Anderson, Kayla N., additional, Mulkey, Sarah B., additional, DeBiasi, Roberta L., additional, Biddle, Cara, additional, Lee, Ellen H., additional, Elmore, Amanda L., additional, Scotland, Sarah J., additional, Sowunmi, Similoluwa, additional, Longcore, Nicole D., additional, Ahmed, Muhammad, additional, Langlois, Peter H., additional, Khuwaja, Salma, additional, Browne, Shea Elizabeth, additional, Lind, Leah, additional, Shim, Kyoo, additional, Gosciminski, Michael, additional, Blumenfeld, Rachel, additional, Khuntia, Shreya, additional, Halai, Umme-Aiman, additional, Locklear, Autumn, additional, Chan, Mary, additional, Willabus, Teri’, additional, Tonzel, Julius, additional, Marzec, Natalie S., additional, Barreto, Nianest Alers, additional, Sanchez, Connie, additional, Fornoff, Jane, additional, Hale, Shelby, additional, Nance, Amy, additional, Iguchi, Lisa, additional, Adibhatla, Sowmya N., additional, Potts, Emily, additional, Schiffman, Elizabeth, additional, Raman, Devin, additional, McDonald, Morgan F., additional, Stricklin, Brandi, additional, Ludwig, Elizabeth, additional, Denson, Lindsay, additional, Contreras, Dianna, additional, Romitti, Paul A., additional, Ferrell, Emily, additional, Marx, Meghan, additional, Signs, Kimberly, additional, Cook, Amie, additional, Leedom, Vinita Oberoi, additional, Beauregard, Suzann, additional, Orantes, Lucia C., additional, Cronquist, Laura, additional, Roush, Lesley, additional, Godfred-Cato, Shana, additional, Gilboa, Suzanne M., additional, Meaney-Delman, Dana, additional, Honein, Margaret A., additional, Moore, Cynthia A., additional, and Tong, Van T., additional

Published
2023
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35. Abstract 16727: Cardiac Complications of SARS CoV-2 Associated Multi-System Inflammatory Syndrome in Children (mis-c)

Author

Harahsheh, Ashraf S, SABLE, Craig A, Loke, Yue-hin, DeBiasi, Roberta L, Olivieri, Laura, Donofrio, Mary T, Parikh, Kavita, Berul, Charles I, Austin, Ashley, Bell, Michael, Christopher, Adam, Cross, Russell R, Dham, Niti, Frank, Lowell, Kline, Jaclyn N, Ronis, Tova, Smith, Karen L, Spurney, Christopher, Srinivasalu, Hemalatha, Wessel, David L, Zhang, Jing, and Krishnan, Anita

Published
2020
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36. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis

Author

Messacar, Kevin, Sillau, Stefan, Hopkins, Sarah E., Otten, Catherine, Wilson-Murphy, Molly, Wong, Brian, Santoro, Jonathan D., Treister, Andrew, Bains, Harlori K., Torres, Alcy, Zabrocki, Luke, Glanternik, Julia R., Hurst, Amanda L., Martin, Jan A., Schreiner, Teri, Makhani, Naila, DeBiasi, Roberta L., Kruer, Michael C., Tremoulet, Adriana H., Van Haren, Keith, Desai, Jay, Benson, Leslie A., Gorman, Mark P., Abzug, Mark J., Tyler, Kenneth L., and Dominguez, Samuel R.

Published
2018
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40. Contributors

Author

Abzug, Mark J., Acharya, Krishna K., Adams, Denise M., Adelson, Stewart, Adrian, Molly C., Ahlfeld, Shawn K., Aiken, John J., Akdis, Cezmi A., Albokhari, Daniah, Alderman, Elizabeth M., Ali, Omar, Allen-Rhoades, Wendy A., Almutlaq, Nourah N., Amos, Louella B., Anari, Jason B., Anderson, Karl E., Anupindi, Sudha A., Appleby, Brian S., Ardoin, Stacy P., Arkader, Alexandre, Armangué, Thaís, Arndt, Carola A.S., Arnold, Danielle E., Artis, Adrianne R., Asher, David M., Asselin, Barbara L., Astley, Christina M., Atkinson, Norrell K., Augustine, Erika F., Augustyn, Marilyn C., Bacharier, Leonard B., Bacino, Carlos A., Bailey, Zinzi D., Balamuth, Frances B., Baldassano, Robert N., Baldwin, Keith D., Bales, Christina B., Balistreri, William F., Balwani, Manisha, Bamba, Vaneeta, Banerji, Aleena, Bang, Janet Y., Barai, Nikita, Baranowski, Katherine, Barclay, Sarah F., Barkoudah, Elizabeth, Barrero-Castillero, Alejandra, Barrett, Katherine J., Barron, Karyl S., Basel, Donald, Bass, Dorsey M., Bassett, Mary T., Bassiri, Hamid, Baum, Rebecca A., Behrens, Edward M., Bell, Michael J., Benjamin, Daniel K., Jr., Bennett, Amanda E., Bergerson, Jenna R.E., Bernstein, Daniel, Bernstein, Henry H., Bice-Urbach, Brittany J., Bielory, Brett P., Bielory, Leonard, Blanchard, Samra S., Blanchette, Eliza, Blatter, Joshua A., Bleyer, Archie, Boas, Steven R., Bock, Margret E., Boggs, Sarah R., Boivin, Michael J., Bonn, Julie, Bonthius, Daniel J., Boppana, Suresh B., Bordini, Brett J., Borst, Alexandra J., Bosse, Kristopher R., Boyer, Kenneth M., Brady, Patrick W., Brady, Rebecca C., Brady, Samuel L., Branchford, Brian R., Brandow, Amanda M., Brandsma, Erik, Breault, David T., Breuner, Cora Collette, Bridgemohan, Carolyn F., Britt, William J., Brower, Laura, Brown, Maria D., Brownell, Jefferson N., Browning, Meghen B., Brunetti-Pierri, Nicola, Bunyavanich, Supinda, Burstein, Danielle S., Bustinduy, Amaya L., Buyon, Jill P., Cabada, Miguel M., Cada, Michaela, Cairo, Mitchell S., Calello, Diane P., Cameron, Lindsay H., Campbell, Angela J.P., Candelaria, Margo, Cannon, Laura, Carlin, Rebecca F., Carlucci, James G., Carr, Michael R., Carrigan, Robert B., Carter, Rebecca G., Carter-Hamilton, Gail V., Case, Abigail, Chang, Pearl W., Chelimsky, Gisela G., Chelimsky, Thomas, Chemaitilly, Wassim, Chiotos, Kathleen, Chiu, Yvonne E., Chong, Hey Jin, Chou, Stella T., Christ, Lori A., Christenson, John C., Chugh, Ankur A., Cieslak, Theodore J., Claes, Donna J., Coates, Thomas D., Sánchez Códez, María I., Coffin, Susan E., Cohen, Mitchell B., Cohen, Susan S., Cole, F. Sessions, III, Collaco, J. Michael, Collins, James W., Jr., Congeni, Joseph A., Conrad, Máire A., Corcoran, Justin N., Corley, Alexandra M.S., Cox, Amanda L., Coyle, Anne M., Coyne-Beasley, Tamera, Craig, Sansanee S., Creighton, Sarah M., Crigger, Chad B., Crowe, James E., Jr., Culbert, Gabriel, Czinn, Steven J., Dalal, Aarti S., Dalmau, Josep, D’Andrea, Lynn A., Danziger-Isakov, Lara A., Darville, Toni, David, Richard J., Davidoff, Katharine, Davidson, Loren T., Davidson, Richard S., Davies, H. Dele, Davis, Stephanie D., Davis-Kankanamge, Christina, Daw, Najat C., Dean, Shannon L., DeBiasi, Roberta L., Delair, Shirley, DeLaroche, Amy M., De León-Crutchlow, Diva D., Oquendo Del Toro, Helen M., Del Valle Mojica, Coralee, DeMaso, David R., Dendrinos, Melina L., Dent, Arlene E., Desnick, Robert J., Deterding, Robin R., Devarajan, Prasad, deVeber, Gabrielle A., Dhar, Vineet K., Dhossche, Julie M., Diab, Liliane K., Di Carlo, Heather N., Dietz, Harry C., III, Dietze-Fiedler, Megan L., DiMeglio, Linda A., Dixon, Bradley P., DiVasta, Amy D., Dlamini, Nomazulu, Dobbs, Katherine R., Dodhia, Sonam N., Doerholt, Katja, Dolin, Cara D., Dominguez, Samuel R., Donohoue, Patricia A., Dow, Jennifer, Downes, Kevin J., Doyle, Daniel A., Doyle, Jefferson J., Dror, Yigal, Dubowitz, Howard, Dumler, J. Stephen, Duncan, Andrea F., Durant, Nefertiti H., Dvergsten, Jeffrey A., Earing, Michael G., Eberly, Col. Matthew D., Egan, Marie E., Eichenwald, Eric C., Elkadri, Abdul-Aziz K., Englander, Elizabeth, Ericson, Jessica E., Erkan, Elif, Etzel, Ruth A., Evans, Sarah Helen, Faherty, Erin, Falk, Marni J., Familiar-Lopez, Itziar, Fargo, John H., Feemster, Kristen A., Fehnel, Katie P., Feigelman, Susan, Feldman, Amy G., Feldman, Heidi M., Fels, Edward C., Felner, Eric I., Feng, Sing-Yi, Ferkol, Thomas W., Jr., Finberg, Karin E., Finder, Jonathan D., Fiorino, Kristin N., Fischer, Philip R., Fitzpatrick, Anne M., Flannery, Dustin D., Fleming, Nicholas L., Flood, Veronica H., Flores, Francisco X., Flynn, Joseph T., Flynn, Patricia M., Foglia, Elizabeth E., Forkey, Heather C., Forman, Joel A., Freeman, Alexandra F., Friedman, Deborah M., Friedman, Susan A., Friehling, Erika D., Fritz, Stephanie A., Frush, Donald P., Fuleihan, Ramsay L., Gahagan, Sheila, Gallagher, Patrick G., Galloway, David P., Gans, Hayley A., Garber, Andrea K., Gardiner, Paula M., Garibaldi, Luigi R., Gauthier, Gregory M., Gerber, Jeffrey S., Gershon, Anne A., Ghadersohi, Saied, Gibbs, Kathleen A., Gibson, Mark, Gigante, Joseph, Gigliotti, Francis, Gilley, Stephanie P., Gilliam, Walter S., Ginde, Salil, Girotto, John A., Goldfarb, Samuel B., Goldman, David L., Goldman, Stanton C., Gómez-Duarte, Oscar G., Good, Misty, Goodbody, Christine M., Goodman, Denise M., Goodman, Tracey, Goodyer, William R., Gordon, Catherine M., Gordon, Leslie B., Gordon, Rebecca J., Gordon-Lipkin, Eliza, Gorelik, Michael, Gower, W. Adam, Graber, Evan G., Graff, Zachary T., Graham, Robert J., Green, Cori M., Green, Michael, Greenbaum, Larry A., Greenbaum, V. Jordan, Greiner, Mary V., Griffiths, Anne G., Grizzle, Kenneth L., Groner, Judith A., Grumach, Anete Sevciovic, Gueye-Ndiaye, Seyni, Guz-Mark, Anat, Haamid, Fareeda, Haddad, Gabriel G., Haddad, Joseph, Jr., Haemer, Matthew A., Hagan, Joseph F., Jr., Haider, Suraiya K., Hakim, Hana, Haldeman-Englert, Chad R., Halstead, Scott B., Hamie, Lamiaa, Hammerschlag, Margaret R., Hammershaimb, E. Adrianne, Hampton, Elisa, Hamvas, Aaron, Hanchard, Neil A., Hanley, Patrick C., Hanna, Melisha G., Harijan, Pooja D., Harrison, Douglas J., Harstad, Elizabeth B., Haslam, David B., Hauck, Fern R., Havers, Fiona P., Hayes, Ericka V., Heard-Garris, Nia J., Hedrick, Holly L., Hemingway, Cheryl, Heneghan, Chelsea, Hernandez, Michelle L., Hernandez-Trujillo, Vivian P., Hernandez Tejada, Fiorela N., Herrick, Heidi M., Hershey, Andrew D., Herzog, Cynthia E., Heston, Sarah M., Hijazi, Ghada, Hill, Samantha V., Hochberg, Jessica, Hodes, Deborah, Hoefgen, Holly R., Holinger, Lauren D., Holland-Hall, Cynthia M., Hollenbach, Laura L., Holler-Managan, Yolanda F., Hooper, David K., Hooven, Thomas A., Hoover-Fong, Julie E., Hopper, Rachel K., Hord, Jeffrey D., Horn, B. David, Horstmann, Helen M., Hotez, Peter J., House, Samantha A., Howard, Ashley C., Howard, Mary Beth, Hsu, Evelyn K., Hsu, Katherine, Huddleston, Heather G., Huh, Winston W., Humphrey, Stephen R., Hunstad, David A., Hunger, Stephen P., Hunt, Carl E., Huppert, Stacey S., Huppler, Anna R., Hurt, Hallam, Izumi, Kosuke, Jackson, Allison M., Jackson, Mary Anne, Jaffe, Ashlee M., James, Kiera M., Janowski, Andrew B., Jenssen, Brian P., Jinnah, H.A., John, Chandy C., Johansen, Kari, Johnson, Susan L., Johnston, Brian D., Jongco, Artemio M., III, Josephson, Cassandra D., Joyce, Joel C., Jyonouchi, Soma, Kabbany, Mohammad Nasser, Kabbouche, Marielle, Kacperski, Joanne, Kadry, Nadia A., Kaj-Carbaidwala, Batul, Kalish, Jennifer M., Kamat, Deepak, Kansra, Alvina R., Kanter, David M., Kao, Carol M., Kapavarapu, Prasanna K., Kattan, Jacob, Kelly, Andrea, Kelly, Desmond P., Kelly, Matthew S., Kelly, Michael E., Kendi, Sadiqa, Kerem, Eitan, Kerr, Julie M., Khan, David A., Khan, Seema, Khatami, Ameneh, Khaytin, Ilya, Kier, Catherine, Kilinsky, Alexandra, Kim, Chong-Tae, Kim, Jung Won, Kim, Rosa K., King, J. Michael, Kirschen, Matthew P., Kishnani, Priya S., Klawonn, Meghan A., Klein, Bruce L., Klein, Bruce S., Kliegman, Alison S., Kliegman, Robert M., Kneyber, Martin C.J., Koch, William C., Kochanek, Patrick M., Kodish, Eric, Kohlhoff, Stephan A., Kortepeter, Mark G., Kotloff, Karen L., Koumbourlis, Anastassios C., Krause, Peter J., Krebs, Nancy F., Kreipe, Richard E., Krug, Steven E., Kwiatkowski, Janet L., Kwon, Jennifer M., Ladisch, Stephan, Lakser, Oren J., Lalor, Leah, Lam, Simon, Lambert, Michele P., Lampe, Christina, Landry, Gregory L., Lane, Wendy G., Larson, A. Noelle, LaRussa, Phillip S., Lawrence, J. Todd R., Lee, Brendan, Lee, Erica H., Leiding, Jennifer W., Lemmon, Monica E., Lesser, Daniel J., Lestrud, Steven O., Leung, Donald Y.M., Levas, Michael N., Liacouras, Chris A., Lipkin, Paul H., Liptzin, Deborah R., Liu, Andrew H., Lo, Mindy S., Lo, Stanley F., Long, Sarah S., Lord, Katherine, Macias, Charles G., Macias, Michelle M., Macumber, Ian R., Magnusson, Mark R., Magoulas, Pilar L., Maguire, Kathleen J., Mahajan, Prashant V., Majzoub, Joseph A., Mamula, Petar, Manak, Colleen K., Mangus, Courtney W., Manoli, Irini, Manzur, Adnan Y., Maqbool, Asim, Maranich, Col. Ashley M., Margetts, Miranda, Margolis, David, Marin, Mona, Marini, Joan C., Markowitz, Morri, Maroushek, Stacene R., Marsh, Justin D., Marshall, Trisha L., Martin, Kari L., Masson, Vicki K., Matalon, Dena R., Matalon, Reuben K., Mathijssen, Irene M.J., Reddy Matta, Sravan Kumar, Maxwell, Elizabeth C., Maybank, Aletha, McCabe, Megan E., McCain, Darla H., McColley, Susanna A., McConnico, Neena, McCormick, Elizabeth M., McDonald, Christine M., McGovern, Margaret M., McGrath-Morrow, Sharon A., McInerney, Alissa, McKinney, Jeffrey S., McLeod, Rima, McVay-Gillam, Marcene R., Meade, Julia C., Meehan, William P., III, Mejias, Asuncion, Melby, Peter C., Melzer-Lange, Marlene D., Merves, Jamie F., Messacar, Kevin B., Michaels, Marian G., Michniacki, Thomas F., Mikati, Mohamad A., Miller-Handley, Hilary E., Mink, Jonathan W., Mirasola, Karolyn, Mistovich, R. Justin, Mohr, Emma L., Montoya-Williams, Diana, Moon, Rachel Y., Morava, Eva, Moreno, Megan A., Morgan, Ryan W., Morrison, Peter E., Morrison, Wynne, Mukhopadhyay, Sagori, Munoz, Flor M., Munson, David A., Murphy, Timothy F., Murray, Karen F., Murray, Thomas S., Mutlu, Levent, Nagata, Jason M., Narula, Sona, Nataro, James P., Navsaria, Dipesh, Nduati, Ruth W., Nehus, Edward J., Nelson, Maureen R., Neri, Caitlin M., Nevin, Mary A., Newburger, Jane W., Newmark, Jonathan, Nield, Linda S., Niermeyer, Susan, Nocton, James J., Nogee, Lawrence M., Noje, Corina, Nowak-Wegrzyn, Anna H., Obaro, Stephen K., Obeid, Makram M., O’Callaghan, Kevin P., Oleszek, Joyce L., Olitsky, Scott E., Olsson, John M., O’Neill, Meghan E., Onigbanjo, Mutiat T., Opoka, Robert O., Orenstein, Walter A., Orkin, Sarah H., Orscheln, Rachel C., Ortega, Camile, O’Toole, Timothy R., Owens, Judith A., Ozen, Seza, Pach, Sophie, Pachter, Lee M., Padhye, Amruta, Pandurangi, Sindhu, Pak-Gorstein, Suzinne, Palla, John, Palmieri, Tina L., Palmieri, Jessica M., Pappas, Diane E., Parent, John J., Parga-Belinkie, Joanna J., Parikh, Bijal A., Parker, Alasdair P.J., Partridge, Emily A., Patel, Ami B., Patel, Trusha, Patrick, Stephen W., Patterson, Briana C., Pelosi, Emanuele, Permar, Sallie R., Perry, Michael, Perry, Tamara T., Peters, Mark J., Peters, Timothy R., Peterson, Stacy J.B., Phelan, Rachel A., Pinto, Anna L., Pipan, Mary, Player, Brittany, Prince, William Benjamin, Proctor, Mark R., Prozora, Stephanie, Pryor, Howard I., II, Pyles, Lee A., Quinn, Molly M., Quint, Elisabeth H., Rabinovich, C. Egla, Raffini, Leslie J., Ragoonanan, Dristhi S., Rahman, Shamima, Ralston, Shawn L., Ram, Sanjay, Ramilo, Octavio, Ramirez, Kacy A., Rand, Casey M., Rasmussen, Sonja A., Rathke, Kevin M., Ratner, Adam J., Ratner, Lee, Reed, Ann M., Reich, Patrick J., Reif, Shimon, Reller, Megan E., Remick, Katherine E., Remiker, Allison S., Reyes, Jorge D., Richardson, Katherine M., Rintoul, Natalie E., Ritchey, A. Kim, Robinson, Angela Byun, Rodrigues, Kristine Knuti, Rogers, Michael E., Romano, Mary E., Roosevelt, Genie E., Roper, Stephen M., Rosenthal, Stephen M., Ross, A. Catharine, Rossano, Joseph W., Rothman, Jennifer A., Rotta, Alexandre T., Rozenfeld, Ranna A., Russo, Michael E., Ryan, Kelsey S., Ryan, Monique M., Ryu, Julie, Sabbagh, Sara E., Sachdev, H.P.S., Sadarangani, Manish, Sadun, Rebecca E., Sahin, Mustafa, Saint-Cyr, Martine, Salata, Robert A., Salazar, José H., Salvana, Edsel Maurice T., Samelson-Jones, Benjamin J., Sammons, Julia S., Sampson, Hugh A., Samsel, Chase B., Sandora, Thomas J., Sankar, Wudbhav N., Sarnaik, Ashok P., Sato, Alice I., Satter, Lisa Forbes, Scaggs Huang, Felicia A., Schaffzin, Joshua K., Schechter, Michael S., Schilling, Samantha, Schleiss, Mark R., Schluter, W. William, Schondelmeyer, Amanda C., Schroeder, James W., Jr., Schulte, Elaine E., Schuster, Jennifer E., Schuster, Marcy, Schuster, Mark A., Scott, Daryl A., Scott, John P., Seaborg, Kristin A., Seed, Patrick C., Serwint, Janet R., Shah, Dheeraj, Shah, Samir S., Shah, Shivang S., Shamir, Raanan, Shanti, Christina M., Shapiro, Bruce K., Shaywitz, Bennett A., Shaywitz, Sally E., Shchelochkov, Oleg A., Shulman, Stanford T., Sicherer, Scott H., Simmons, Jeffrey M., Simões, Eric A.F., Simonsen, Kari A., Simpson, Tess S., Sinclair-McBride, Keneisha R., Singh, Arunjot, Sink, Jacquelyn R., Sisk, Bryan A., Sivaraman, Vidya, Slattery, Susan M., Slavotinek, Anne M., Smith, Jessica R., Smith-Whitley, Kim, Solensky, Roland, Son, Mary Beth F., Soranno, Danielle E., Sosa, Tina K., Soto-Rivera, Carmen L., Sosinsky, Laura Stout, Souder, Emily E., Souverbielle, Cristina Tomatis, Spearman, Paul, Spiegel, David A., Spinks-Franklin, Adiaha I.A., Sprecher, Alicia J., Squires, James E., Srivastava, Siddharth, St. Geme, Joseph W., III, St. John, Rachel D., Stambough, Kathryn C., Stanberry, Lawrence R., Starke, Jeffrey R., Starr, Taylor B., Steenhoff, Andrew P., Stein, Ronen E., Steinbach, William J., Stillwell, Terri L., Stone, Deborah L., Su, Stefani, Sucato, Gina S., Suchy, Frederick J., Sullivan, Kathleen E., Swami, Sanjeev K., Szafron, Vibha A., Szilagyi, Moira, Taha, Dalal, Tan, Libo, Tantisira, Kelan G., Taylor, Alex M., Tchapyjnikov, Dmitry, Tesini, Brenda L., Theobald, Jillian L., Thielen, Beth K., Thom, Christopher S., Thornburg, Courtney D., Tieder, Joel S., Tissières, Pierre, Tolentino, Victorio R., Jr., Topjian, Alexis A., Tower, Richard L., Trachtman, Rebecca, Triebwasser, Jourdan E., Trowbridge, Sara K., Truglio, Joseph M., Tubergen, David G., Turk, Margaret A., Tymon-Rosario, Joan R., Ufberg, Paul J., Ullrich, Christina, Ullrich, Nicole, Valika, Taher S., Van Hare, George F., Van Mater, Heather A., Varnell, Charles D., Jr., Vash-Margita, Alla, Vece, Timothy J., Vemana, Aarthi P., Venditti, Charles P., Vepraskas, Sarah, Verbsky, James W., Vermilion, Jennifer A., Vickery, Brian P., Vockley, Jerry, Voynow, Judith A., Walch, Abby, Waldrop, Stephanie W., Walker, David M., Walkovich, Kelly J., Walter, Heather J., Wambach, Jennifer A., Wamithi, Susan, Wang, Julie, Wang, Marie E., Wangler, Michael F., Ware, Stephanie M., Washam, Matthew C., Wasserman, Jonathan D., Wassner, Ari J., Watson, Andrew M., Wattier, Rachel L., Weber, David R., Webster, Jennifer, Weese-Mayer, Debra E., Weinberg, Jason B., Weinman, Jason P., Weisman, Steven J., Weiss, Anna K., Weiss, Scott L., Weiss, Pamela F., Weitzman, Carol C., Wells, Lawrence, Wen, Jessica W., Wendel, Danielle R., Werlin, Steven L., Wexler, Isaiah D., Whitaker, Alexander S., White, A. Clinton, Jr., White, Perrin C., Willoughby, Rodney E., Jr., Wilschanski, Michael, Wiley, Susan E., Williams, Brendan A., Wilson, Karen M., Wilson, Pamela E., Winell, Jennifer J., Witters, Peter, Wolf, Joshua, Wolfe, Joanne, Wolfgram, Peter M., Woods, Brandon T., Wright, Benjamin L., Wright, Terry W., Wu, Eveline Y., Yagupsky, Pablo, Yang, Edward, Yang, Kesi C., Yang, Ming, Yaron, Michael, Younger, Sarah B., Yuskaitis, Christopher J., Zachariah, Philip, Zafar, Muhammad S., Zahler, Stacey G., Zajac, Lauren M., Zaky, Wafik, Zaspel, Jennifer A., Zerra, Patricia E., Zhou, Amy, Zuckerman, Barry S., and Zur, Karen B.

Published
2025
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41. Oral Valganciclovir Initiated Beyond One Month of Age for the Treatment of Sensorineural Hearing Loss Caused by Congenital Cytomegalovirus Infection

Author

Kimberlin, David, primary, Aban, Inmaculada, additional, Peri, Kalyani, additional, Nishikawa, Javier K., additional, Bernatoniene, Jolanta, additional, Emonts, Marieke, additional, Klein, Nigel, additional, Bamford, Alasdair, additional, DeBiasi, Roberta L., additional, Faust, Saul N., additional, Jones, Christine, additional, McMaster, Paddy, additional, Caserta, Mary, additional, Ahmed, Amina, additional, Sharland, Mike, additional, Demmler-Harrison, Gail, additional, Hackett, Scott, additional, Sánchez, Pablo J., additional, Shackley, Fiona, additional, Kelly, Dominic F., additional, Dennehy, Penelope H., additional, Storch, Gregory A., additional, Whitley, Richard J., additional, and Griffiths, Paul, additional

Published
2023
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45. Preschool neurodevelopment in Zika virus-exposed children without congenital Zika syndrome

Author

Mulkey, Sarah B., primary, Peyton, Colleen, additional, Ansusinha, Emily, additional, Corn, Elizabeth, additional, Arroyave-Wessel, Margarita, additional, Zhang, Anqing, additional, Biddle, Cara, additional, Gutierrez, Corina, additional, Sorkar, Andrea, additional, Cure, Andres, additional, Cure, Daniela, additional, du Plessis, Adre J., additional, DeBiasi, Roberta L., additional, Msall, Michael E., additional, and Cure, Carlos, additional

Published
2022
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48. Factors Associated With Severe Illness in Patients Aged &lt;21 Years Hospitalized for COVID-19

Author

Choudhary, Rewa, primary, Webber, Bryant J., additional, Womack, Lindsay S., additional, Dupont, Hannah K., additional, Chiu, Sophia K., additional, Wanga, Valentine, additional, Gerdes, Megan E., additional, Hsu, Sophia, additional, Shi, Dallas S., additional, Dulski, Theresa M., additional, Idubor, Osatohamwen I., additional, Wendel, Arthur M., additional, Agathis, Nickolas T., additional, Anderson, Kristi, additional, Boyles, Tricia, additional, Click, Eleanor S., additional, Da Silva, Juliana, additional, Evans, Mary E., additional, Gold, Jeremy A.W., additional, Haston, Julia C., additional, Logan, Pamela, additional, Maloney, Susan A., additional, Martinez, Marisol, additional, Natarajan, Pavithra, additional, Spicer, Kevin B., additional, Swancutt, Mark, additional, Stevens, Valerie A., additional, Rogers-Brown, Jessica, additional, Chandra, Gyan, additional, Light, Megan, additional, Barr, Frederick E., additional, Snowden, Jessica, additional, Kociolek, Larry K., additional, McHugh, Matthew, additional, Wessel, David L., additional, Simpson, Joelle N., additional, Gorman, Kathleen C., additional, Breslin, Kristen A., additional, DeBiasi, Roberta L., additional, Thompson, Aaron, additional, Kline, Mark W., additional, Boom, Julie A., additional, Singh, Ila R., additional, Dowlin, Michael, additional, Wietecha, Mark, additional, Schweitzer, Beth, additional, Morris, Sapna Bamrah, additional, Koumans, Emilia H., additional, Ko, Jean Y., additional, Siegel, David A., additional, and Kimball, Anne A., additional

Published
2022
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