29 results on '"Deau, Emmanuel"'
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2. Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome
3. Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer’s Disease Drug Candidate
4. Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A
5. Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B
6. Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases
7. Synthesis and molecular modelling studies of 8-arylpyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors
8. Microwave-assisted synthesis of novel N-(4-phenylthiazol-2-yl)-benzo[d]thiazole-, thiazolo[4,5-b]pyridine-, thiazolo[5,4-b]pyridine- and benzo[d]oxazole-2-carboximidamides inspired by marine topsentines and nortopsentines
9. Rational multistep synthesis of a novel polyfunctionalized benzo[d]thiazole and its thiazolo[5,4-b]pyridine analogue
10. Serodolin, a β-arrestin–biased ligand of 5-HT 7 receptor, attenuates pain-related behaviors
11. Structure–Activity Relationship in the Leucettine Family of Kinase Inhibitors
12. Serodolin, a β-arrestin-biased ligand of 5-HT7 receptor, attenuates pain-related behaviors.
13. Organocatalytic enantioselective synthesis of β-amino sulfonic acid derivatives
14. Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors.
15. A Meldrum's Acid Based Multicomponent Synthesis of N‐Fmoc‐isoxazolidin‐5‐ones: Entry to N‐Fmoc‐β‐amino Acids
16. Cu/Pd-catalyzed C-2-H arylation of quinazolin-4(3H)-ones with (hetero)aryl halides
17. Synthesis of novel 7-substituted pyrido[2′,3′:4,5]furo[3,2-d]pyrimidin-4-amines and their N-aryl analogues and evaluation of their inhibitory activity against Ser/Thr kinases
18. Convenient one-pot synthesis of N3-substituted pyrido[2,3-d]-, pyrido[3,4-d]-, pyrido[4,3-d]-pyrimidin-4(3H)-ones, and quinazolin-4(3H)-ones analogs
19. ChemInform Abstract: Cu/Pd-Catalyzed C-2-H Arylation of Quinazolin-4(3H)-ones with (Hetero)aryl Halides.
20. Rational Design, Pharmacomodulation, and Synthesis of Dual 5-Hydroxytryptamine 7 (5-HT7)/5-Hydroxytryptamine 2A (5-HT2A) Receptor Antagonists and Evaluation by [18F]-PET Imaging in a Primate Brain
21. Microwave-Assisted [3+2] Cycloaddition and Suzuki-Miyaura Cross-Coupling for a Concise Access to Polyaromatic Scaffolds
22. Synthèse asymétrique de l’épi-jasmonate de méthyle et de son énantiomère (ent-épi-jasmonate de méthyle) par voie chimique et enzymatique
23. Asymmetric synthesis of methyl epi-jasmonate and its enantiomer (methyl ent-epi-jasmonate) by chemo-stereoselective and enzymatic routes
24. Microwave-Assisted Kinetic Resolution of Homochiral (Z)-Cyclooct-5-ene-1,2-diol and (Z)-2-Acetoxycyclooct-4-enyl Acetate Using Lipases
25. ChemInform Abstract: Microwave‐Assisted [3 + 2] Cycloaddition and Suzuki—Miyaura Cross‐Coupling for a Concise Access to Polyaromatic Scaffolds.
26. ChemInform Abstract: Synthesis of Novel 7‐Substituted Pyrido[2′,3′:4,5]furo[3,2‐d]pyrimidin‐4‐amines (VII) and Their N‐Aryl Analogues (IX) and Evaluation of Their Inhibitory Activity Against Ser/Thr Kinases.
27. ChemInform Abstract: Convenient One-Pot Synthesis of N3-Substituted Pyrido[2,3-d]-, Pyrido[3,4-d]-, Pyrido[4,3-d]-pyrimidin-4(3H)-ones, and Quinazolin-4(3H)-ones Analogues.
28. ChemInform Abstract: Highlights in 1,2,3‐Dithiazole Chemistry
29. Convenient one-pot synthesis of N3-substituted pyrido[2,3-d]-, pyrido[3,4-d]-, pyrido[4,3-d]-pyrimidin-4(3H)-ones, and quinazolin-4(3H)-ones analogs.
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