6 results on '"Deepshikha Mehrotra"'
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2. Evaluation of Cytotoxic Effects of Purified Mercury in Human Gingival Fibroblasts—In vitro Study
- Author
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Deepshikha Mehrotra, Rajmohan Y. Shetty, Jayaprakasha Shetty, B. Mohana Kumar, A. Veena Shetty, Shraddha Shetty, and Rashmi N. Shetty
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cytotoxicity ,dental amalgam ,human gingival fibroblasts ,purified mercury ,viability ,proliferation ,Pharmacy and materia medica ,RS1-441 ,Analytical chemistry ,QD71-142 - Abstract
Background: Since the introduction of amalgam for tooth fillings, there have been concerns that mercury toxicity could pose unacceptable health risks. Rasa shastra is an ancient medical discipline that focuses on the utilization of metals and minerals for the treatment of diseases. Nevertheless, these minerals cannot be directly administered to the human body in their natural state due to their potential adverse effects. Hence, for medicinal purposes, these metals and minerals need to undergo purification (Shodhana) to eliminate impurities and modify their physical, chemical, and biological characteristics. Methodology: Human gingival fibroblasts (HGF) were exposed to commercially available mercury (CA-Hg) and ayurvedically purified mercury (AP-Hg) at concentrations of 6.25 μM, 12.5 μM, 25 μM and 50 μM. The unexposed HGF cultured in basal media was considered a control. All the samples were cultured for 24 hours and 48 hours, and the cytotoxicity was analyzed by MTT assay. Results: Cell viability between the control and experimental groups varied at 24 hours, however, the results were not statistically significant (p>0.05). At 48 hours, cell viability was higher in the AP-Hg group as compared to the CA-Hg group at the concentration of 6.25 μM, and the difference was statistically significant (p
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- 2024
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3. Multidisciplinary Approach in the Management of Maxillary Anterior Region Dental Trauma: A Case Report
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Deepshikha Mehrotra, Rajmohan Y Shetty, and Amarshree A Shetty
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avulsion ,bone grafting ,complicated crown fracture ,transitional implants ,Medicine - Abstract
Traumatic Dental Injuries (TDIs) to the maxillary anterior teeth occur frequently in paediatric and adolescent populations. Prompt diagnosis, correct treatment planning, and a multidisciplinary approach are pertinent aspects of successfully managing multiple TDIs in a patient. The present case report of a 13-year-old female patient describes a multidisciplinary approach necessary to successfully manage dental trauma of an avulsed maxillary central incisor and a complicated crown fracture involving the maxillary left lateral incisor in an adolescent. The complicated crown-root fracture was treated with endodontic therapy, followed by the placement of a fibrereinforced post, core build-up, and the cementing of a porcelain-fused-to-metal crown. Bone grafting with a mandibular symphysis block autograft, followed by prosthetic rehabilitation with transitional implants, was performed to restore the aesthetics, form, and function of the avulsed maxillary central incisors. The use of osseointegrated implants has gained wide acceptance in the adult population. However, due to concerns regarding growth, their use in the paediatric population is not as common. This accounts for a scarcity of clinical cases reported in the literature. There are no established guidelines for the placement of implants in growing patients. Thus, authors believe that the present case report contributes to the literature on this subject. The treatment of this complex, multi-dental injury in the maxillary anterior region of a young female required a holistic approach with a step-wise progressive, long-term treatment plan. Traumatic injuries in adolescent patients can adversely impact their oral health-related quality of life if not treated correctly.
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- 2023
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4. Comparative evaluation of the effect of audio and virtual reality distraction on the dental anxiety of healthy and mild intellectually disabled children
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Deepshikha Mehrotra and R Manju
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behavior modification ,dental anxiety ,intellectual disability ,virtual reality ,Dentistry ,RK1-715 - Abstract
Context: Dental environment is one of the most anxiety-provoking stimuli for children, which makes patient management a constant challenge in both typically growing and intellectually disabled children. Distraction is a nonpharmacological technique to manage anxiety in children during dental treatment. Aim: This study compares the effect of audio and virtual reality (VR) distraction on the dental anxiety of healthy and mild intellectually disabled children. Methods: Forty children aged 6–14 years were divided into two groups (Group I: children with mild intellectual disability and Group II: healthy children). Groups I and II were further subdivided into two subgroups of 10 children each, based on the distraction technique given to them during the first appointment. After 1 month, we carried out a cross-over of the subgroups. Anxiety levels were measured using physiological and observational parameters at three-time intervals. Statistical Analysis: Performed using paired t-test for the intergroup comparison and Wilcoxon Signed Rank test for the intra-group comparison. Results: A decrease in the pulse rate, improvement in oxygen saturation levels, and lower Venham's anxiety rating scores were observed on introducing audio and VR distraction in all the subgroups. The inter-group comparison revealed that audio and VR were more effective in healthy children than children with mild intellectual disabilities. Conclusions: Audio and VR distraction techniques can be employed successfully to reduce anxiety in children with mild intellectual disability and healthy children undergoing dental restorative treatment.
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- 2023
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5. Herbal Dentistry- A Narrative Review
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Deepshikha Mehrotra and R Manju
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anti-inflammatory ,anti-microbial ,herbal medicine ,traditional medicine ,Medicine - Abstract
The use of medicinal herbs in dentistry continues to expand rapidly across the globe. Herbal dentistry presents an attractive alternative to conventional synthetic materials. With a shift towards evidence-based dental practice, there is a need for dental clinicians to be fully aware of the alternatives and options currently available to them. This review article provides insight into the various herbal products currently available in dentistry. It provides a better understanding of the mechanism of action of the herbal products used to treat various dental problems. This narrative review identifies and summarises the most common medicinal herbs in various preventive and therapeutic spheres of dentistry. High anti-microbial, anti-inflammatory, antioxidant, and immunomodulatory activities along with wound healing ability and sedative-anxiolytic were identified to be the properties favouring use of these medicinal plants in dentistry. Although the natural alternatives discussed in the current narrative review have shown to be either superior or comparable to the synthetically available options, further long-term in-vivo clinical trials are required to substantiate this evidence and justify the replacement of later with herbal alternatives in dentistry.
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- 2023
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6. Comparison of Class Room Lectures with Fishbowl-Snowball Activity for Dental Undergraduate Students: An Observational Study
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Amitha M. Hegde, Shreema Shetty, and Deepshikha Mehrotra
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Background Traditional classroom lectures have been the backbone of the education system for a long time although this method is most effective but it may not always permit active engagement with the matter and learn it. In contrast, active teaching formats such as fishbowl and snowball techniques allow students to participate in the task of attaining knowledge by shifting the target from preceptor to student, thereby allowing a better understanding of the concepts. Methodology A total of 80 final-year undergraduate dental students were included in this study. Each student was informed regarding study design and protocol. A lecture on the principles of Pediatric Endodontics was delivered to the students in small groups using the routine virtual method, following which a pre-test activity questionnaire and formal thinking questionnaire were given to the students for scoring. Following this, the class of 80 was divided into smaller groups of four each and the Fishbowl–snowball activity was performed. A post-test activity questionnaire and formal thinking questionnaire were given once again to the students for scoring. The mean pre and post-test scores were statistically analyzed using paired t-test by statistical software SPSS version 20. A p-value of Results The overall mean difference between pre and post-test activity and formal thinking scores was seen to be statistically significant (p Conclusion It was seen that a combination of fishbowl and snowball method of teaching led to more satisfactory results as compared with the routine classroom teaching method.
- Published
- 2022
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