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1. Diagnosis and treatment of pancreatic duct disruption or disconnection: an international expert survey and case vignette study

Author

Albert, J., Arvanitakis, M., Badaoui, A., Barthet, M., van Biervliet, G., Bradley, E., Boermeester, M., Buchler, M., Cappendijk, V., Charnley, R., Connor, S., Dejong, C., Dellinger, P., Dervenis, C., Deviere, J., Dumonceau, J., van Eijck, C., Fagenholz, P., Castillo, C.Fernandez-del, Forsmark, C., Freeman, M., French, J., van Goor, H., Haveman, J.W., van Hooft, J., Hucl, T., Isaji, S., Jagielski, M., Karjula, H., Lerch, M., Lévy, P., Lillemoe, K., Löhr, M., Mayerle, J., Mittal, A., Morgan, D., Moon, S., Nieuwenhuijs, V., Sarr, M., Seewald, S., Sherman, S., Singh, V., Siriwardena, A., Stommel, M., Tann, M., Téllez-Avina, F., Timmer, R., Traverso, W., Radenkovic, D., Rana, S., Rebours, V., Pelaez-Luna, M., Poley, J.W., Windsor, J., Zaheer, A., Zyromski, N., Boxhoorn, Lotte, Timmerhuis, Hester C., Verdonk, Robert C., Besselink, Marc G., Bollen, Thomas L., Bruno, Marco J., Elmunzer, B. Joseph, Fockens, Paul, Horvath, Karen D., van Santvoort, Hjalmar C., and Voermans, Rogier P.

Published
2021
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2. Are the current difficulty scores for laparoscopic liver surgery telling the whole story? An international survey and recommendations for the future

Author

Abu Hilal, M., Aldrighetti, L., Al Saati, H., Alseidi, A., Aroori, S., Belli, G., Besselink, M., Edwin, B., D'Hondt, M., Dagher, I., Dejong, C., Geller, D., Hamady, Z., Hamoui, M., Isaksson, B., Ivanecz, A., Le Roux, G., Lesurtel, M., O'Rouke, N., Prasad, R., Prieto Calvo, M., Reddy, S., Rotellar, F., Santoyo, J., Soonawalla, Z., Soubrane, O., Stavrou, G., Subar, D., Sutcliffe, R., Tanis, P., Troisi, R., Van Dam, Ronald, Wakabayashi, G., White, S., Halls, Mark C., Cherqui, Daniel, Taylor, Mark A., Primrose, John N., and Abu Hilal, Mohammed

Published
2018
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11. Surgery for multiple endocrine neoplasia type 1-related insulinoma

Author

van Beek, D. J., Nell, S., Verkooijen, H. M., Borel Rinkes, I. H. M., Valk, G. D., Vriens, M. R., Goudet, P., Vella, A., Donegan, D., Bartsch, D. K., Manoharan, J., Perrier, N. D., Christakis, I., Brandi, M. L., Zarnegar, R., Postma, E. L., Kebebew, E., Nockel, P., Brunaud, L., Pasternak, J. D., Kluijfhout, W. P., Sturgeon, C., Giri, S., Bonsing, B. A., van Eijck, C. H., van Goor, H., de Kleine, R. H. J., van Dijkum, E. J. Nieveen, Dejong, C. H. C., Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Clinical Genetics, and Department of Finance

Subjects
Male, endocrine system diseases, Kaplan-Meier Estimate, 0302 clinical medicine, Postoperative Complications, Multiple endocrine neoplasia, Child, Aged, 80 and over, Middle Aged, medicine.anatomical_structure, Treatment Outcome, 030220 oncology & carcinogenesis, HPB, Child, Preschool, Original Article, Female, Pancreas, hormones, hormone substitutes, and hormone antagonists, Adult, medicine.medical_specialty, endocrine system, Adolescent, Enucleation, Clinical Decision-Making, 030209 endocrinology & metabolism, Hypoglycemia, 03 medical and health sciences, Young Adult, Pancreatectomy, medicine, Multiple Endocrine Neoplasia Type 1, Humans, MEN1, General, Survival rate, Insulinoma, Aged, Retrospective Studies, business.industry, Original Articles, medicine.disease, Surgery, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Pancreatic Neoplasms, Localized disease, Neoplasm Recurrence, Local, business, Follow-Up Studies
Abstract

Background Insulinomas are found in 10–15 per cent of patients with multiple endocrine neoplasia type 1 (MEN1) and lead to life‐threatening hypoglycaemia. Surgical outcome and the optimal surgical strategy for MEN1‐related insulinoma are unknown. Methods Patients with MEN1‐related insulinomas were identified in 46 centres in Europe and North America between 1990 and 2016. Insulinomas were considered localized if the lesion was in the pancreatic head or body/tail. Patients with pancreatic neuroendocrine tumours throughout the pancreas were suspected of having multifocal insulinoma. The primary outcome was postoperative hypoglycaemia, defined as persistent hypoglycaemia, or recurrent hypoglycaemia caused by a new insulinoma or insulin‐producing liver metastases. Hypoglycaemia‐free survival was estimated by the Kaplan–Meier method. Results Ninety‐six patients underwent resection for MEN1‐related insulinoma. Sixty‐three and 33 patients had localized and multifocal insulinomas respectively. After a median follow‐up of 8 (range 1–22) years, one patient (1 per cent) had persistent disease and six (6 per cent) had developed recurrent disease, of whom four had a new insulinoma. The 10‐year hypoglycaemia‐free survival rate was 91 (95 per cent c.i. 80 to 96) per cent. Of those with localized disease, 46 patients underwent pancreatic resection and 17 enucleation. One of these patients had persistent disease and one developed recurrent insulinoma. Among patients with multifocal disease, three developed new insulinomas and two developed insulin‐producing liver metastases. Conclusion Surgery for MEN1‐related insulinoma is more successful than previously thought., In this cohort of 96 patients with resected multiple endocrine neoplasia 1 (MEN1)‐related insulinomas, seven patients (7 per cent) developed postoperative persistent or recurrent hypoglycaemia after a median follow‐up of 8 years. The 10‐year hypoglycaemia‐free survival rate was 91 (95 per cent c.i. 80 to 96) per cent. For patients with localized insulinoma, enucleation seems the preferred procedure. PPPD, pylorus‐preserving pancreatoduodenectomy. Outcomes good

Published
2020
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12. Treatment and overall survival of four types of non-metastatic periampullary cancer:nationwide population-based cohort study

Author

de Jong, Evelien J.M., van der Geest, Lydia G., Besselink, Marc G., Bouwense, Stefan A.W., Buijsen, Jeroen, Dejong, C. H.C., Koerkamp, Bas G., Heij, Lara R., de Hingh, Ignace H.J.T., Hoge, Chantal, Kazemier, Geert, van Laarhoven, Hanneke W.M., de Meijer, Vincent E., Stommel, Martijn W.J., Tjan-Heijnen, Vivianne C.G., Valkenburg-van Iersel, Liselot B.J., Wilmink, Johanna W., Geurts, Sandra M.E., de Vos-Geelen, Judith, de Jong, Evelien J.M., van der Geest, Lydia G., Besselink, Marc G., Bouwense, Stefan A.W., Buijsen, Jeroen, Dejong, C. H.C., Koerkamp, Bas G., Heij, Lara R., de Hingh, Ignace H.J.T., Hoge, Chantal, Kazemier, Geert, van Laarhoven, Hanneke W.M., de Meijer, Vincent E., Stommel, Martijn W.J., Tjan-Heijnen, Vivianne C.G., Valkenburg-van Iersel, Liselot B.J., Wilmink, Johanna W., Geurts, Sandra M.E., and de Vos-Geelen, Judith

Abstract

Background: Periampullary adenocarcinoma consists of pancreatic adenocarcinoma (PDAC), distal cholangiocarcinoma (DC), ampullary cancer (AC), and duodenal adenocarcinoma (DA). The aim of this study was to assess treatment modalities and overall survival by tumor origin. Methods: Patients diagnosed with non-metastatic periampullary cancer in 2012–2018 were identified from the Netherlands Cancer Registry. OS was studied with Kaplan–Meier analysis and multivariable Cox regression analyses, stratified by origin. Results: Among the 8758 patients included, 68% had PDAC, 13% DC, 12% AC, and 7% DA. Resection was performed in 35% of PDAC, 56% of DC, 70% of AC, and 59% of DA. Neoadjuvant and/or adjuvant therapy was administered in 22% of PDAC, 7% of DC, 7% of AC, and 12% of DA. Three-year OS was highest for AC (37%) and DA (34%), followed by DC (21%) and PDAC (11%). Adjuvant therapy was associated with improved OS among PDAC (HR = 0.62; 95% CI 0.55–0.69) and DC (HR = 0.69; 95% CI 0.48–0.98), but not AC (HR = 0.87; 95% CI 0.62–1.22) and DA (HR = 0.85; 95% CI 0.48–1.50). Conclusion: This retrospective study identified considerable differences in treatment modalities and OS between the four periampullary cancer origins in daily clinical practice. An improved OS after adjuvant chemotherapy could not be demonstrated in patients with AC and DA.

Published
2022

15. Management of the pancreatic transection plane after left (distal) pancreatectomy: Expert consensus guidelines by the International Study Group of Pancreatic Surgery (ISGPS)

Author

Miao, Y, Lu, Z, Yeo, C, Vollmer, C, Fernandez-del Castillo, C, Ghaneh, P, Halloran, C, Kleeff, J, de Rooij, T, Werner, J, Falconi, M, Friess, H, Zeh, H, Izbicki, J, He, J, Laukkarinen, J, Dejong, C, Lillemoe, K, Conlon, K, Takaori, K, Gianotti, L, Besselink, M, Del Chiaro, M, Montorsi, M, Tanaka, M, Bockhorn, M, Adham, M, Olah, A, Salvia, R, Shrikhande, S, Hackert, T, Shimosegawa, T, Zureikat, A, Ceyhan, G, Peng, Y, Wang, G, Huang, X, Dervenis, C, Bassi, C, Neoptolemos, J, Buchler, M, Miao Y., Lu Z., Yeo C. J., Vollmer C. M., Fernandez-del Castillo C., Ghaneh P., Halloran C. M., Kleeff J., de Rooij T., Werner J., Falconi M., Friess H., Zeh H. J., Izbicki J. R., He J., Laukkarinen J., Dejong C. H., Lillemoe K. D., Conlon K., Takaori K., Gianotti L., Besselink M. G., Del Chiaro M., Montorsi M., Tanaka M., Bockhorn M., Adham M., Olah A., Salvia R., Shrikhande S. V., Hackert T., Shimosegawa T., Zureikat A. H., Ceyhan G. O., Peng Y., Wang G., Huang X., Dervenis C., Bassi C., Neoptolemos J. P., Buchler M. W., Miao, Y, Lu, Z, Yeo, C, Vollmer, C, Fernandez-del Castillo, C, Ghaneh, P, Halloran, C, Kleeff, J, de Rooij, T, Werner, J, Falconi, M, Friess, H, Zeh, H, Izbicki, J, He, J, Laukkarinen, J, Dejong, C, Lillemoe, K, Conlon, K, Takaori, K, Gianotti, L, Besselink, M, Del Chiaro, M, Montorsi, M, Tanaka, M, Bockhorn, M, Adham, M, Olah, A, Salvia, R, Shrikhande, S, Hackert, T, Shimosegawa, T, Zureikat, A, Ceyhan, G, Peng, Y, Wang, G, Huang, X, Dervenis, C, Bassi, C, Neoptolemos, J, Buchler, M, Miao Y., Lu Z., Yeo C. J., Vollmer C. M., Fernandez-del Castillo C., Ghaneh P., Halloran C. M., Kleeff J., de Rooij T., Werner J., Falconi M., Friess H., Zeh H. J., Izbicki J. R., He J., Laukkarinen J., Dejong C. H., Lillemoe K. D., Conlon K., Takaori K., Gianotti L., Besselink M. G., Del Chiaro M., Montorsi M., Tanaka M., Bockhorn M., Adham M., Olah A., Salvia R., Shrikhande S. V., Hackert T., Shimosegawa T., Zureikat A. H., Ceyhan G. O., Peng Y., Wang G., Huang X., Dervenis C., Bassi C., Neoptolemos J. P., and Buchler M. W.

Abstract

Background: The aim was to evaluate the various operative techniques and outcomes used to manage the pancreatic transection plane (or stump) during a left (distal) pancreatectomy and to develop expert consensus guidelines. Methods: Evidence-based, clinically relevant questions were discussed and then were circulated among members of the International Study Group of Pancreatic Surgery. After agreement on the questions and statements, voting in a 9-point Likert scale was used to gauge the level of objective support for each. Results: Studies using the International Study Group of Pancreatic Surgery definition of postoperative pancreatic fistula including 16 randomized trials were reviewed to generate a series of statements set into 14 domains. There was strong consensus in the following statements: there was no difference in the postoperative pancreatic fistula rate after left pancreatectomy between the handsewn and stapler techniques; a stapling technique could not be used in all cases of left pancreatectomy; the use of an energy-based tissue sealant or a chemical sealant device or combinations of these did not impact the postoperative pancreatic fistula rate; there was no difference in the postoperative pancreatic fistula rate between the open, laparoscopic, or robotic approaches; and there are 1 or more clinically important, patient-related risk factors associated with the postoperative pancreatic fistula rate. There was weak or conditional agreement on the use of prophylactic somatostatin analogs, stents, stump closure, stump anastomosis, and the role of abdominal drains. Conclusion: Areas of strong consensus suggests a change in clinical practice and priority setting. Eight domains with lower agreement will require novel approaches and large multicenter studies to determine future key areas of practice.

Published
2020

16. Defining Major Surgery: A Delphi Consensus Among European Surgical Association (ESA) Members

Author

Martin, D., Mantziari, S., Demartines, N., Hubner, M., Bismuth, H., Sarr, M. G., Strasberg, S. M., Wexner, S. D., Adham, M., Altomare, D. F., Andersson, R., Bechstein, W., Biondo, S., Bockhorn, M., Bonavina, L., Rituerto, D. C., Clavien, P. -A., De Manzini, N., Decker, G., Dejong, C. H., Dervenis, C., Farges, O., Figueras, J., Fingerhut, A. L., Friess, H., Glehen, O., Gnant, M., Gutschow, C., Hahnloser, D., Hamberger, B., Hamming, J. F., Holscher, A. H., Izbicki, J. R., Jonas, S., Karamarkovic, A., Kehlet, H., Leppaniemi, A. K., Lerut, J., Line, P. -D., Lodge, J. P. A., Meakins, J. L., Montorsi, M., Nafteux, P., Naredi, P., Olah, A., Panis, Y., Pardo, F., Parks, R. W., Pedrazzoli, S., Pessaux, P., Marques, H. P., Poggioli, G., Popescu, I., Puolakkainen, P. A., Ramia Angel, J. M., Rasanen, J., Reynolds, J. V., Rosati, R., Saeger, H. -D., Schneeberger, S., Schneider, P. M., Soreide, K., Stippel, D., Toso, C., Tuech, J. -J., Tukiainen, E. J., Van Hillegersberg, R., Wijnhoven, B., Winter, D. C., Zaninotto, G., Surgery, Martin, D., Mantziari, S., Demartines, N., Hubner, M., Bismuth, H., Sarr, M. G., Strasberg, S. M., Wexner, S. D., Adham, M., Altomare, D. F., Andersson, R., Bechstein, W., Biondo, S., Bockhorn, M., Bonavina, L., Rituerto, D. C., Clavien, P. -A., De Manzini, N., Decker, G., Dejong, C. H., Dervenis, C., Farges, O., Figueras, J., Fingerhut, A. L., Friess, H., Glehen, O., Gnant, M., Gutschow, C., Hahnloser, D., Hamberger, B., Hamming, J. F., Holscher, A. H., Izbicki, J. R., Jonas, S., Karamarkovic, A., Kehlet, H., Leppaniemi, A. K., Lerut, J., Line, P. -D., Lodge, J. P. A., Meakins, J. L., Montorsi, M., Nafteux, P., Naredi, P., Olah, A., Panis, Y., Pardo, F., Parks, R. W., Pedrazzoli, S., Pessaux, P., Marques, H. P., Poggioli, G., Popescu, I., Puolakkainen, P. A., Ramia Angel, J. M., Rasanen, J., Reynolds, J. V., Rosati, R., Saeger, H. -D., Schneeberger, S., Schneider, P. M., Soreide, K., Stippel, D., Toso, C., Tuech, J. -J., Tukiainen, E. J., Van Hillegersberg, R., Wijnhoven, B., Winter, D. C., Zaninotto, G., Martin D., Mantziari S., Demartines N., Hubner M., Bismuth H., Sarr M.G., Strasberg S.M., Wexner S.D., Adham M., Altomare D.F., Andersson R., Bechstein W., Biondo S., Bockhorn M., Bonavina L., Rituerto D.C., Clavien P.-A., De Manzini N., Decker G., Dejong C.H., Dervenis C., Farges O., Figueras J., Fingerhut A.L., Friess H., Glehen O., Gnant M., Gutschow C., Hahnloser D., Hamberger B., Hamming J.F., Holscher A.H., Izbicki J.R., Jonas S., Karamarkovic A., Kehlet H., Leppaniemi A.K., Lerut J., Line P.-D., Lodge J.P.A., Meakins J.L., Montorsi M., Nafteux P., Naredi P., Olah A., Panis Y., Pardo F., Parks R.W., Pedrazzoli S., Pessaux P., Marques H.P., Poggioli G., Popescu I., Puolakkainen P.A., Ramia Angel J.M., Rasanen J., Reynolds J.V., Rosati R., Saeger H.-D., Schneeberger S., Schneider P.M., Soreide K., Stippel D., Toso C., Tuech J.-J., Tukiainen E.J., Van Hillegersberg R., Wijnhoven B., Winter D.C., Zaninotto G., ESA Study Group, Sarr, M.G., Strasberg, S.M., Wexner, S.D., Altomare, D.F., Rituerto, D.C., Clavien, P.A., Dejong, C.H., Fingerhut, A.L., Hamming, J.F., Hölscher, A.H., Izbicki, J.R., Leppäniemi, A.K., Line, P.D., Lodge, JPA, Meakins, J.L., Oláh, A., Parks, R.W., Marques, H.P., Puolakkainen, P.A., Ramia Angel, J.M., Reynolds, J.V., Saeger, H.D., Schneider, P.M., Søreide, K., Tuech, J.J., Tukiainen, E.J., Winter, D.C., Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Zurich, Demartines, Nicolas, and Toso, Christian

Subjects
Male, medicine.medical_specialty, Blood transfusion, Consensus, Delphi Technique, medicine.medical_treatment, Delphi method, 610 Medicine & health, Consensu, Likert scale, 03 medical and health sciences, Surgeon, 0302 clinical medicine, Aged, Europe, Humans, Middle Aged, Societies, Medical, Surgeons, Surgical Procedures, Operative/methods, Medical, major surgery, Delphi consensus definition, medicine, Operative / methods, 10217 Clinic for Visceral and Transplantation Surgery, Surgical Procedures, ddc:617, business.industry, Perioperative, Vascular surgery, 2746 Surgery, 3. Good health, Cardiac surgery, Surgery, Cardiothoracic surgery, 030220 oncology & carcinogenesis, Surgical Procedures, Operative, 030211 gastroenterology & hepatology, Societies, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Abdominal surgery, Human
Abstract

Background: Major surgery is a term frequently used but poorly defined. The aim of the present study was to reach a consensus in the definition of major surgery within a panel of expert surgeons from the European Surgical Association (ESA). Methods: A 3-round Delphi process was performed. All ESA members were invited to participate in the expert panel. In round 1, experts were inquired by open- and closed-ended questions on potential criteria to define major surgery. Results were analyzed and presented back anonymously to the panel within next rounds. Closed-ended questions in round 2 and 3 were either binary or statements to be rated on a Likert scale ranging from 1 (strong disagreement) to 5 (strong agreement). Participants were sent 3 reminders at 2-week intervals for each round. 70% of agreement was considered to indicate consensus. Results: Out of 305 ESA members, 67 (22%) answered all the 3 rounds. Significant comorbidities were the only preoperative factor retained to define major surgery (78%). Vascular clampage or organ ischemia (92%), high intraoperative blood loss (90%), high noradrenalin requirements (77%), long operative time (73%) and perioperative blood transfusion (70%) were procedure-related factors that reached consensus. Regarding postoperative factors, systemic inflammatory response (76%) and the need for intensive or intermediate care (88%) reached consensus. Consequences of major surgery were high morbidity (>30% overall) and mortality (>2%). Conclusion: ESA experts defined major surgery according to extent and complexity of the procedure, its pathophysiological consequences and consecutive clinical outcomes.

Published
2020
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20. Diagnosis and treatment of pancreatic duct disruption or disconnection: an international expert survey and case vignette study

Author

Boxhoorn, Lotte, primary, Timmerhuis, Hester C., additional, Verdonk, Robert C., additional, Besselink, Marc G., additional, Bollen, Thomas L., additional, Bruno, Marco J., additional, Elmunzer, B. Joseph, additional, Fockens, Paul, additional, Horvath, Karen D., additional, van Santvoort, Hjalmar C., additional, Voermans, Rogier P., additional, Albert, J., additional, Arvanitakis, M., additional, Badaoui, A., additional, Barthet, M., additional, van Biervliet, G., additional, Bradley, E., additional, Boermeester, M., additional, Buchler, M., additional, Cappendijk, V., additional, Charnley, R., additional, Connor, S., additional, Dejong, C., additional, Dellinger, P., additional, Dervenis, C., additional, Deviere, J., additional, Dumonceau, J., additional, van Eijck, C., additional, Fagenholz, P., additional, Castillo, C.Fernandez-del, additional, Forsmark, C., additional, Freeman, M., additional, French, J., additional, van Goor, H., additional, Haveman, J.W., additional, van Hooft, J., additional, Hucl, T., additional, Isaji, S., additional, Jagielski, M., additional, Karjula, H., additional, Lerch, M., additional, Lévy, P., additional, Lillemoe, K., additional, Löhr, M., additional, Mayerle, J., additional, Mittal, A., additional, Morgan, D., additional, Moon, S., additional, Nieuwenhuijs, V., additional, Sarr, M., additional, Seewald, S., additional, Sherman, S., additional, Singh, V., additional, Siriwardena, A., additional, Stommel, M., additional, Tann, M., additional, Téllez-Avina, F., additional, Timmer, R., additional, Traverso, W., additional, Radenkovic, D., additional, Rana, S., additional, Rebours, V., additional, Pelaez-Luna, M., additional, Poley, J.W., additional, Windsor, J., additional, Zaheer, A., additional, and Zyromski, N., additional

Published
2021
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23. Correction to: Portal Vein Embolization is Associated with Reduced Liver Failure and Mortality in High-Risk Resections for Perihilar Cholangiocarcinoma (Annals of Surgical Oncology, (2020), 10.1245/s10434-020-08258-3)

Author

Olthof P. B., Aldrighetti L., Alikhanov R., Cescon M., Groot Koerkamp B., Jarnagin W. R., Nadalin S., Pratschke J., Schmelzle M., Sparrelid E., Lang H., Guglielmi A., van Gulik T. M., Andreou A., Bartsch F., Benzing C., Buettner S., Capobianco I., de Reuver P., de Savornin Lohman E., Dejong C. H. C., Efanov M., Erdmann J. I., Franken L. C., Frascaroli G., Giglio M. C., Gomez-Gavara C., Heid F., IJzermans J. N. M., Jansson H., Ligthart M. A. P., Maithel S. K., Malago M., Malik H. Z., Muiesan P., Olde Damink S. W. M., Pando E., Quinn L. M., Ratti F., Roberts K. J., Rolinger J., Ruzzenente A., Schadde E., Serenari M., Sultana A., Troisi R., van Laarhoven S., van Vugt J. L. A., Olthof, P. B., Aldrighetti, L., Alikhanov, R., Cescon, M., Groot Koerkamp, B., Jarnagin, W. R., Nadalin, S., Pratschke, J., Schmelzle, M., Sparrelid, E., Lang, H., Guglielmi, A., van Gulik, T. M., Andreou, A., Bartsch, F., Benzing, C., Buettner, S., Capobianco, I., de Reuver, P., de Savornin Lohman, E., Dejong, C. H. C., Efanov, M., Erdmann, J. I., Franken, L. C., Frascaroli, G., Giglio, M. C., Gomez-Gavara, C., Heid, F., Ijzermans, J. N. M., Jansson, H., Ligthart, M. A. P., Maithel, S. K., Malago, M., Malik, H. Z., Muiesan, P., Olde Damink, S. W. M., Pando, E., Quinn, L. M., Ratti, F., Roberts, K. J., Rolinger, J., Ruzzenente, A., Schadde, E., Serenari, M., Sultana, A., Troisi, R., van Laarhoven, S., and van Vugt, J. L. A.

Abstract

In the original article Moritz Schmelzle’s last name is spelled wrong. It is correct as reflected here.

Published
2020

24. Portal Vein Embolization is Associated with Reduced Liver Failure and Mortality in High-Risk Resections for Perihilar Cholangiocarcinoma

Author

Olthof, P. B., Aldrighetti, L., Alikhanov, R., Cescon, M., Groot Koerkamp, B., Jarnagin, W. R., Nadalin, S., Pratschke, J., Schmelze, M., Sparrelid, E., Lang, H., Guglielmi, A., van Gulik, T. M., Andreou, A., Bartsch, F., Benzing, C., Buettner, S., Capobianco, I., de Reuver, P., de Savornin Lohman, E., Dejong, C. H. C., Efanov, M., Erdmann, J. I., Franken, L. C., Frascaroli, G., Giglio, M. C., Gomez-Gavara, C., Heid, F., IJzermans, J. N. M., Jansson, H., Ligthart, M. A. P., Maithel, S. K., Malago, M., Malik, H. Z., Muiesan, P., Olde Damink, S. W. M., Pando, E., Quinn, L. M., Ratti, F., Roberts, K. J., Rolinger, J., Ruzzenente, A., Schadde, E., Serenari, M., Sultana, A., Troisi, R., van Laarhoven, S., van Vugt, J. L. A., Surgery, Academic Medical Center, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Olthof, P. B., Aldrighetti, L., Alikhanov, R., Cescon, M., Groot Koerkamp, B., Jarnagin, W. R., Nadalin, S., Pratschke, J., Schmelze, M., Sparrelid, E., Lang, H., Guglielmi, A., van Gulik, T. M., Andreou, A., Bartsch, F., Benzing, C., Buettner, S., Capobianco, I., de Reuver, P., de Savornin Lohman, E., Dejong, C. H. C., Efanov, M., Erdmann, J. I., Franken, L. C., Frascaroli, G., Giglio, M. C., Gomez-Gavara, C., Heid, F., Ijzermans, J. N. M., Jansson, H., Ligthart, M. A. P., Maithel, S. K., Malago, M., Malik, H. Z., Muiesan, P., Olde Damink, S. W. M., Pando, E., Quinn, L. M., Ratti, F., Roberts, K. J., Rolinger, J., Ruzzenente, A., Schadde, E., Serenari, M., Sultana, A., Troisi, R., van Laarhoven, S., and van Vugt, J. L. A.

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, education, 030230 surgery, Preoperative care, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 03 medical and health sciences, 0302 clinical medicine, Retrospective Studie, Preoperative Care, medicine, Hepatectomy, Humans, Embolization, Abscess, Bile Duct Neoplasm, Aged, Retrospective Studies, portal vein embolization, portal vein embolisation, Perihilar cholangiocarcinoma, Portal Vein, business.industry, Incidence (epidemiology), Liver Neoplasms, Correction, Retrospective cohort study, Middle Aged, Jaundice, medicine.disease, Embolization, Therapeutic, Surgery, Bile Duct Neoplasms, Oncology, Liver Neoplasm, Hepatobiliary Tumors, 030220 oncology & carcinogenesis, Propensity score matching, Cohort, medicine.symptom, business, Liver Failure, Human, Klatskin Tumor
Abstract

Background Preoperative portal vein embolization (PVE) is frequently used to improve future liver remnant volume (FLRV) and to reduce the risk of liver failure after major liver resection. Objective This paper aimed to assess postoperative outcomes after PVE and resection for suspected perihilar cholangiocarcinoma (PHC) in an international, multicentric cohort. Methods Patients undergoing resection for suspected PHC across 20 centers worldwide, from the year 2000, were included. Liver failure, biliary leakage, and hemorrhage were classified according to the respective International Study Group of Liver Surgery criteria. Using propensity scoring, two equal cohorts were generated using matching parameters, i.e. age, sex, American Society of Anesthesiologists classification, jaundice, type of biliary drainage, baseline FLRV, resection type, and portal vein resection. Results A total of 1667 patients were treated for suspected PHC during the study period. In 298 patients who underwent preoperative PVE, the overall incidence of liver failure and 90-day mortality was 27% and 18%, respectively, as opposed to 14% and 12%, respectively, in patients without PVE (p p = 0.005). After propensity score matching, 98 patients were enrolled in each cohort, resulting in similar baseline and operative characteristics. Liver failure was lower in the PVE group (8% vs. 36%, p p p = 0.01), and 90-day mortality (7% vs. 18%, p = 0.03). Conclusion PVE before major liver resection for PHC is associated with a lower incidence of liver failure, biliary leakage, abscess formation, and mortality. These results demonstrate the importance of PVE as an integral component in the surgical treatment of PHC.

Published
2020

28. Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)

Author

Bartels, S. A. L., Vlug, M. S., Hollmann, M. W., Dijkgraaf, M. G. W., Ubbink, D. T., Cense, H. A., van Wagensveld, B. A., Engel, A. F., Gerhards, M. F., Bemelman, W. A., Cuesta, M. A., van Geloven, A. A. W., van der Zaag, E. S., Wind, J., Preckel, B., Bossuyt, P., Gouma, D., Sprangers, M., van Berge Henegouwen, M. I., Tanis, P. J., Buskens, C. J., van Lenthe, Picard I., Bakker, C., DeJong, C. H., van Dam, R. M., van der Peet, D., van Zalingen, E., Noordhuis, A., Goei, T. H., van Tets, W., deWit, L., Clevers, W., Bieleman, A., Coenen, L., Bonekamp, E., van Abeelen, J., van Iterson-de Jong, D., and Krombeen, M.

Published
2014
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29. Comparing practice and outcome of laparoscopic liver resection between high-volume expert centres and nationwide low-to-medium volume centres

Author

Görgec, B, primary, Fichtinger, R S, additional, Ratti, F, additional, Aghayan, D, additional, Van der Poel, M J, additional, Al-Jarrah, R, additional, Armstrong, T, additional, Cipriani, F, additional, Fretland, Å A, additional, Suhool, A, additional, Bemelmans, M, additional, Bosscha, K, additional, Braat, A E, additional, De Boer, M T, additional, Dejong, C H C, additional, Doornebosch, P G, additional, Draaisma, W A, additional, Gerhards, M F, additional, Gobardhan, P D, additional, Hagendoorn, J, additional, Kazemier, G, additional, Klaase, J, additional, Leclercq, W K G, additional, Liem, M S, additional, Lips, D J, additional, Marsman, H A, additional, Mieog, J S D, additional, Molenaar, Q I, additional, Nieuwenhuijs, V B, additional, Nota, C L, additional, Patijn, G A, additional, Rijken, A M, additional, Slooter, G D, additional, Stommel, M W J, additional, Swijnenburg, R J, additional, Tanis, P J, additional, Te Riele, W W, additional, Terkivatan, T, additional, Van den Tol, P M P, additional, Van den Boezem, P B, additional, Van der Hoeven, J A, additional, Vermaas, M, additional, Edwin, B, additional, Aldrighetti, L A, additional, Van Dam, R M, additional, Abu Hilal, M, additional, and Besselink, M G, additional

Published
2021
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31. Diagnosis and treatment of pancreatic duct disruption or disconnection: an international expert survey and case vignette study

Author

Boxhoorn, L. (Lotte), Timmerhuis, H.C. (Hester C.), Verdonk, R.C. (Robert), Besselink, M.G. (Marc), Bollen, T.L. (Thomas), Bruno, M.J. (Marco J.), Elmunzer, B.J. (B. Joseph), Fockens, P. (Paul), Horvath, K.D. (Karen D.), Santvoort, H.C. (Hjalmar) van, Voermans, R.P. (Rogier), Albert, J. (J.), Arvanitakis, M. (M.), Badaoui, A. (A.), Barthet, M. (M.), van Biervliet, G. (G.), Bradley, E. (E.), Boermeester, M.A. (Marja), Buchler, M.W. (M.), Cappendijk, V.C., Charnley, R. (R.), Connor, S. (S.), Dejong, C. (C.), Dellinger, P. (P.), Dervenis, C. (Christos), Deviere, J. (J.), Dumonceau, J.M., Eijck, C.H.J. (Casper) van, Fagenholz, P. (P.), Castillo, C.F.-D. (C.Fernandez-del), Forsmark, C. (C.), Freeman, M. (M.), French, J. (J.), Goor, H. (Harry) van, Haveman, J.W., Hooft, J.E. (Jeanin) van, Hucl, T. (Tomas), Isaji, S. (S.), Jagielski, M. (M.), Karjula, H. (H.), Lerch, M. (M.), Lévy, P. (Philippe), Lillemoe, K. (K.), Löhr, M. (M.), Mayerle, J. (Julia), Mittal, A. (A.), Morgan, D. (D.), Moon, S. (S.), Nieuwenhuijs, V.B. (Vincent), Sarr, M. (M.), Seewald, S. (Stefan), Sherman, S. (S.), Singh, V. (V.), Siriwardena, A. (A.), Stommel, M. (M.), Tann, M. (M.), Téllez-Avina, F. (F.), Timmer, R. (Robin), Traverso, W. (W.), Radenkovic, D. (D.), Rana, S. (S.), Rebours, V. (Vinciane), Pelaez-Luna, M. (M.), Poley, J.-W. (Jan-Werner), Windsor, J. (J.), Zaheer, A. (A.), Zyromski, N. (N.), Boxhoorn, L. (Lotte), Timmerhuis, H.C. (Hester C.), Verdonk, R.C. (Robert), Besselink, M.G. (Marc), Bollen, T.L. (Thomas), Bruno, M.J. (Marco J.), Elmunzer, B.J. (B. Joseph), Fockens, P. (Paul), Horvath, K.D. (Karen D.), Santvoort, H.C. (Hjalmar) van, Voermans, R.P. (Rogier), Albert, J. (J.), Arvanitakis, M. (M.), Badaoui, A. (A.), Barthet, M. (M.), van Biervliet, G. (G.), Bradley, E. (E.), Boermeester, M.A. (Marja), Buchler, M.W. (M.), Cappendijk, V.C., Charnley, R. (R.), Connor, S. (S.), Dejong, C. (C.), Dellinger, P. (P.), Dervenis, C. (Christos), Deviere, J. (J.), Dumonceau, J.M., Eijck, C.H.J. (Casper) van, Fagenholz, P. (P.), Castillo, C.F.-D. (C.Fernandez-del), Forsmark, C. (C.), Freeman, M. (M.), French, J. (J.), Goor, H. (Harry) van, Haveman, J.W., Hooft, J.E. (Jeanin) van, Hucl, T. (Tomas), Isaji, S. (S.), Jagielski, M. (M.), Karjula, H. (H.), Lerch, M. (M.), Lévy, P. (Philippe), Lillemoe, K. (K.), Löhr, M. (M.), Mayerle, J. (Julia), Mittal, A. (A.), Morgan, D. (D.), Moon, S. (S.), Nieuwenhuijs, V.B. (Vincent), Sarr, M. (M.), Seewald, S. (Stefan), Sherman, S. (S.), Singh, V. (V.), Siriwardena, A. (A.), Stommel, M. (M.), Tann, M. (M.), Téllez-Avina, F. (F.), Timmer, R. (Robin), Traverso, W. (W.), Radenkovic, D. (D.), Rana, S. (S.), Rebours, V. (Vinciane), Pelaez-Luna, M. (M.), Poley, J.-W. (Jan-Werner), Windsor, J. (J.), Zaheer, A. (A.), and Zyromski, N. (N.)

Abstract

Background: Pancreatic duct disruption or disconnection is a potentially severe complication of necrotizing pancreatitis. With no existing treatment guidelines, it is unclear whether there is any consensus among experts in clinical practice. We evaluated current expert opinion regarding the diagnosis and treatment of pancreatic duct disruption and disconnection in an international case vignette study. Methods: An online case vignette survey was sent to 110 international expert pancreatologists. Expert selection was based on publications in the last 5 years and/or participation in development of IAP/APA and ESGE guidelines on acute pancreatitis. Consensus was defined as agreement by at least 75% of the experts. Results: The response rate was 51% (n = 56). Forty-four experts (79%) obtained a MRI/MRCP and 52 experts (93%) measured amylase levels in percutaneous drain fluid to evaluate pancreatic duct integrity. The majority of experts favored endoscopic transluminal drainage for infected (peri)pancreatic necrosis and pancreatic duct disruption (84%, n = 45) or disconnection (88%, n = 43). Consensus was lacking regarding the treatment of patients with persistent percutaneous drain production, and with persistent sterile necrosis. Conclusion: This international survey of experts demonstrates that there are many areas for which no consensus existed, providing clear focus for future investigation.

Published
2021
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32. Comparing practice and outcome of laparoscopic liver resection between high-volume expert centres and nationwide low-to-medium volume centres

Author

Zorgeenheid Vaatchirurgie Zorg, MS CGO, Cancer, Görgec, B., Fichtinger, R. S., Ratti, F., Aghayan, D., Van der Poel, M. J., Al-Jarrah, R., Armstrong, T., Cipriani, F., Fretland, ÅA, Suhool, A., Bemelmans, M., Bosscha, K., Braat, A. E., De Boer, M. T., Dejong, C. H.C., Doornebosch, P. G., Draaisma, W. A., Gerhards, M. F., Gobardhan, P. D., Hagendoorn, J., Kazemier, G., Klaase, J., Leclercq, W. K.G., Liem, M. S., Lips, D. J., Marsman, H. A., Mieog, J. S.D., Molenaar, Q. I., Nieuwenhuijs, V. B., Nota, C. L., Patijn, G. A., Rijken, A. M., Slooter, G. D., Stommel, M. W.J., Swijnenburg, R. J., Tanis, P. J., Te Riele, W. W., Terkivatan, T., Van den Tol, P. M.P., Van den Boezem, P. B., Van der Hoeven, J. A., Vermaas, M., Edwin, B., Aldrighetti, L. A., Van Dam, R. M., Abu Hilal, M., Besselink, M. G., Zorgeenheid Vaatchirurgie Zorg, MS CGO, Cancer, Görgec, B., Fichtinger, R. S., Ratti, F., Aghayan, D., Van der Poel, M. J., Al-Jarrah, R., Armstrong, T., Cipriani, F., Fretland, ÅA, Suhool, A., Bemelmans, M., Bosscha, K., Braat, A. E., De Boer, M. T., Dejong, C. H.C., Doornebosch, P. G., Draaisma, W. A., Gerhards, M. F., Gobardhan, P. D., Hagendoorn, J., Kazemier, G., Klaase, J., Leclercq, W. K.G., Liem, M. S., Lips, D. J., Marsman, H. A., Mieog, J. S.D., Molenaar, Q. I., Nieuwenhuijs, V. B., Nota, C. L., Patijn, G. A., Rijken, A. M., Slooter, G. D., Stommel, M. W.J., Swijnenburg, R. J., Tanis, P. J., Te Riele, W. W., Terkivatan, T., Van den Tol, P. M.P., Van den Boezem, P. B., Van der Hoeven, J. A., Vermaas, M., Edwin, B., Aldrighetti, L. A., Van Dam, R. M., Abu Hilal, M., and Besselink, M. G.

Published
2021

48. Comparing Practice and Outcome of Laparoscopic Liver Resection Between High-volume Expert Centres and Nationwide Low-medium Volume Centres

Author

Görgec, B., primary, Fichtinger, R., additional, Ratti, F., additional, Aghayan, D., additional, van der Poel, M., additional, Al-Jarrah, R., additional, Armstrong, T., additional, Cipriani, F., additional, Fretland, Å., additional, Suhool, A., additional, Bemelmans, M., additional, Bosscha, K., additional, Braat, A., additional, de Boer, M., additional, Dejong, C., additional, Doornebosch, P., additional, Draaisma, W., additional, Gerhards, M., additional, Gobardhan, P., additional, Hagendoorn, J., additional, Kazemier, G., additional, Klaase, J., additional, Leclerq, W., additional, Liem, M., additional, Lips, D., additional, Marsman, H., additional, Mieog, J., additional, Molenaar, Q., additional, Nieuwenhuijs, V., additional, Nota, C., additional, Patijn, G., additional, Rijken, A., additional, Slooter, G., additional, Stommel, M., additional, Swijnenburg, R., additional, Tanis, P., additional, Riele, W. Te, additional, Terkivatan, T., additional, van den Tol, P., additional, van den Boezem, P., additional, van der Hoeven, J., additional, Vermaas, M., additional, Edwin, B., additional, Aldrighetti, L., additional, van Dam, R., additional, Hilal, M. Abu, additional, and Besselink, M., additional

Published
2021
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49. A Population-based Study on Incidence, Treatment and Survival in Ampullary Cancer in the Netherlands

Author

de Jong, E., primary, Geurts, S., additional, van der Geest, L., additional, Besselink, M., additional, Bouwense, S., additional, Buijsen, J., additional, Dejong, C., additional, Heij, L., additional, Groot Koerkamp, B., additional, de Hingh, I.H., additional, Hoge, C., additional, Kazemier, G., additional, van Laarhoven, H.W., additional, de Meijer, V.E., additional, Mohammad, N.H., additional, Strijker, M., additional, Timmermans, K.C., additional, Valkenburg-van Iersel, L.B., additional, Wilmink, H., additional, Tjan-Heijnen, V., additional, and de Vos-Geelen, J., additional

Published
2021
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