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1. Epidemiological Characteristics of Shiga Toxin-Producing Escherichia coli Responsible for Infections in the Polish Pediatric Population

Author

Seliga-Gąsior Dominika, Sokól-Leszczyñska Beata, Krzysztoñ-Russjan Jolanta, Wierzbicka Diana, Stępieñ-Hołubczat Karolina, Lewandowska Paulina, Frankiewicz Ewa, Cacko Andrzej, Leszczyñska Beata, Demkow Urszula, and Podsiadły Edyta

Subjects
shiga toxin-producing escherichia coli, diarrhea, hemolytic uremic syndrome, epidemiology, poland, Genetics, QH426-470, Microbiology, QR1-502
Abstract

Shiga toxin-producing Escherichia coli (STEC) are zoonotic pathogens causing hemorrhagic colitis and hemolytic uremic syndrome (HUS) in children and the elderly. Stool samples were collected from 180 children hospitalized in five pediatric centers in Poland in 2018–2022. Direct stx1/stx2 gene detection by PCR in feces and E. coli isolates was performed. Antibiotic susceptibility was tested according to EUCAST v.12. Randomly selected isolates were serotyped with O157 antiserum and genotyped by pulsed-field gel electrophoresis (PFGE). A total of 44 E. coli isolates were confirmed as STEC by PCR. Among them, 84.4% were positive for stx2, and equally 6,8% for only stx1 and both stx1 and stx2 genes. The stx1 gene was also found in one Citrobacter freundii isolate. E. coli serotype O157 was present in 97.6% of the isolates. STEC infections most often occurred between June-October with a peak in July and August (51%). The highest, 77.8% of STEC isolates were found in the 1–5 years old group. No extended-spectrum β-lactamases (ESBL) were found. Resistance only to amoxicillin/clavulanic acid (24.4%), piperacillin/tazobactam (3%), cefotaxime (6%), gentamicin (6%), ciprofloxacin (3%), azithromycin (3%), trimethoprim/sulfamethoxazole (24,2%) was detected. PFGE analysis showed 18 PFGE types with no clonal distribution. Eight isolates with A, B, and C PFGE types showed genetic relatedness in the type with no detection of transmission way of distribution. STEC strains pose a serious threat to human health, therefore demographic and epidemiological characteristics are crucial for their surveillance.

Published
2024
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7. Clinical Course and Outcome of Community-Acquired Bacterial Meningitis in Cancer Patients

Author

Paciorek, Marcin, Bednarska, Agnieszka, Krogulec, Dominika, Makowiecki, Michał, Kowalska, Justyna D., Bursa, Dominik, Świderska, Anna, Puła, Joanna, Raczyńska, Joanna, Skrzat-Klapaczyńska, Agata, Radkowski, Marek, Demkow, Urszula, Laskus, Tomasz, Horban, Andrzej, Crusio, Wim E., Series Editor, Lambris, John D., Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2020
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9. The 'Optimum Volume' of Acrylic Cement Filling for Treating Vertebral Compression Fractures: A Morphometric Study of Thoracolumbar Vertebrae

Author

Dzierżanowski, Jarosław, Winklewski, Paweł J., Skotarczak, Monika, Baczkowska-Waliszewska, Zuzanna, Szmuda, Tomasz, Zdanowski, Szymon, Radkowski, Marek, Łuczkiewicz, Piotr, Czapiewski, Piotr, Słoniewski, Paweł, Szurowska, Edyta, Demkow, Urszula, Szarmach, Arkadiusz, LAMBRIS, JOHN D., Series Editor, CRUSIO, WIM E., Series Editor, REZAEI, NIMA, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2019
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10. Relative Cerebral Blood Transit Time Decline and Neurological Improvement in Patients After Internal Carotid Artery Stenting

Author

Szarmach, Arkadiusz, Małkiewicz, Marta A., Zdun-Ryżewska, Agata, Halena, Grzegorz, Radkowski, Marek, Dzierżanowski, Jarosław, Chwojnicki, Kamil, Muc, Adam, Damaszko, Tomasz, Łyźniak, Piotr, Piskunowicz, Maciej, Szurowska, Edyta, Demkow, Urszula, Winklewski, Paweł J., COHEN, IRUN R., Editorial Board Member, LAJTHA, ABEL, Editorial Board Member, LAMBRIS, JOHN D., Editorial Board Member, PAOLETTI, RODOLFO, Editorial Board Member, REZAEI, NIMA, Editorial Board Member, and Pokorski, Mieczyslaw, editor

Published
2019
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11. Radiological Response and Neutrophil-to-Lymphocyte Ratio as Predictive Factors for Progression-Free and Overall Survival in Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib

Author

Kucharz, Jakub, Dumnicka, Paulina, Giza, Agnieszka, Demkow, Urszula, Kusnierz–Cabala, Beata, Demkow, Tomasz, Wiechno, Pawel, COHEN, IRUN R., Editorial Board Member, LAJTHA, ABEL, Editorial Board Member, LAMBRIS, JOHN D., Editorial Board Member, PAOLETTI, RODOLFO, Editorial Board Member, REZAEI, NIMA, Editorial Board Member, and Pokorski, Mieczyslaw, editor

Published
2019
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12. Vitamin D and Calcium Homeostasis in Infants with Urolithiasis

Author

Szmigielska, Agnieszka, Pańczyk-Tomaszewska, Małgorzata, Borowiec, Małgorzata, Demkow, Urszula, Krzemień, Grażyna, COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, Lambris, John, Series Editor, Paoletti, Rodolfo, Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2019
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13. Morphometric Analysis of the Lumbar Vertebrae Concerning the Optimal Screw Selection for Transpedicular Stabilization

Author

Dzierżanowski, Jarosław, Skotarczyk, Monika, Baczkowska-Waliszewska, Zuzanna, Krakowiak, Mateusz, Radkowski, Marek, Łuczkiewicz, Piotr, Czapiewski, Piotr, Szmuda, Tomasz, Słoniewski, Paweł, Szurowska, Edyta, Winklewski, Paweł J., Demkow, Urszula, Szarmach, Arkadiusz, COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, Lambris, John, Series Editor, Paoletti, Rodolfo, Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2019
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14. Coupling of Blood Pressure and Subarachnoid Space Oscillations at Cardiac Frequency Evoked by Handgrip and Cold Tests: A Bispectral Analysis

Author

Gruszecki, Marcin, Tkachenko, Yurii, Kot, Jacek, Radkowski, Marek, Gruszecka, Agnieszka, Basiński, Krzysztof, Waskow, Monika, Guminski, Wojciech, Anand, Jacek Sein, Wtorek, Jerzy, Frydrychowski, Andrzej F., Demkow, Urszula, Winklewski, Pawel J., COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, Lambris, John, Series Editor, Paoletti, Rodolfo, Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2019
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19. Oscillations of Subarachnoid Space Width as a Potential Marker of Cerebrospinal Fluid Pulsatility

Author

Gruszecki, Marcin, Nuckowska, Magdalena K., Szarmach, Arkadiusz, Radkowski, Marek, Szalewska, Dominika, Waskow, Monika, Szurowska, Edyta, Frydrychowski, Andrzej F., Demkow, Urszula, Winklewski, Pawel J., COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, LAMBRIS, JOHN D., Series Editor, PAOLETTI, RODOLFO, Series Editor, REZAEI, NIMA, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2018
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20. The Diagnostics of Human Steroid Hormone Disorders

Author

Dobosz, Małgorzata, Manda-Handzlik, Aneta, Pyrżak, Beata, Demkow, Urszula, COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, and Pokorski, Mieczyslaw, editor

Published
2018
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21. Spontaneous Elimination of Hepatitis C Virus Infection

Author

Janiak, Maciej, Caraballo Cortes, Kamila, Demkow, Urszula, Radkowski, Marek, COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, and Pokorski, Mieczyslaw, editor

Published
2018
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24. Melatonin and Metformin Diminish Oxidative Stress in Heart Tissue in a Rat Model of High Fat Diet and Mammary Carcinogenesis

Author

Kurhaluk, Natalia, Bojkova, Bianka, Radkowski, Marek, Zaitseva, Olga V., Kyriienko, Svitlana, Demkow, Urszula, Winklewski, Pawel J., COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, LAMBRIS, JOHN D., Series Editor, PAOLETTI, RODOLFO, Series Editor, REZAEI, NIMA, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2018
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27. Osteoprotegerin, Receptor Activator of Nuclear Factor Kappa B Ligand, and Growth Hormone/Insulin-Like Growth Factor-1 Axis in Children with Growth Hormone Deficiency

Author

Witkowska-Sędek, Ewelina, Rumińska, Małgorzata, Stelmaszczyk-Emmel, Anna, Sobol, Maria, Demkow, Urszula, Pyrżak, Beata, COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, LAMBRIS, JOHN D., Series Editor, PAOLETTI, RODOLFO, Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2018
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28. Cognitive Predictors of Cortical Thickness in Healthy Aging

Author

Naumczyk, Patrycja, Sawicka, Angelika K., Brzeska, Beata, Sabisz, Agnieszka, Jodzio, Krzysztof, Radkowski, Marek, Czachowska, Karolina, Winklewski, Paweł J., Finc, Karolina, Szurowska, Edyta, Demkow, Urszula, Szarmach, Arkadiusz, COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, LAMBRIS, JOHN D., Series Editor, PAOLETTI, RODOLFO, Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2018
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29. Immunomodulatory Role of Vitamin D: A Review

Author

Skrobot, Agnieszka, Demkow, Urszula, Wachowska, Małgorzata, COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, LAMBRIS, JOHN D., Series Editor, PAOLETTI, RODOLFO, Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2018
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30. Influence of Different Bacteria Strains Isolated from Septic Children on Release and Degradation of Extracellular Traps by Neutrophils from Healthy Adults

Author

Bystrzycka, Weronika, Sieczkowska, Sandra, Manda-Handzlik, Aneta, Rogulska, Joanna, Moskalik, Aneta, Demkow, Urszula, Ciepiela, Olga, COHEN, IRUN R., Series Editor, LAJTHA, ABEL, Series Editor, LAMBRIS, JOHN D., Series Editor, PAOLETTI, RODOLFO, Series Editor, Rezaei, Nima, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2018
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31. Thyroid Autoimmunity in Girls with Turner Syndrome

Author

Witkowska-Sędek, Ewelina, Borowiec, Ada, Kucharska, Anna, Chacewicz, Karolina, Rumińska, Małgorzata, Demkow, Urszula, Pyrżak, Beata, COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, and Pokorski, Mieczyslaw, editor

Published
2017
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32. Enzymatic Activity of Candida spp. from Oral Cavity and Urine in Children with Nephrotic Syndrome

Author

Olczak-Kowalczyk, Dorota, Roszkowska-Blaim, Maria, Dąbkowska, Maria, Swoboda-Kopeć, Ewa, Gozdowski, Dariusz, Mizerska-Wasiak, Małgorzata, Demkow, Urszula, Pańczyk-Tomaszewska, Małgorzata, COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, and Pokorski, Mieczyslaw, editor

Published
2017
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35. Renalase in Children with Glomerular Kidney Diseases

Author

Skrzypczyk, Piotr, Przychodzień, Joanna, Mizerska-Wasiak, Małgorzata, Kuźma-Mroczkowska, Elżbieta, Okarska-Napierała, Magdalena, Górska, Elżbieta, Stelmaszczyk-Emmel, Anna, Demkow, Urszula, Pańczyk-Tomaszewska, Małgorzata, COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, Rezaei, Nima, Series editor, and Pokorski, Mieczyslaw, editor

Published
2017
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37. Synergistic Activity for Natural and Synthetic Inhibitors of Angiogenesis Induced by Murine Sarcoma L-1 and Human Kidney Cancer Cells

Author

Bałan, Barbara J., Siwicki, Andrzej K., Pastewka, Krzysztof, Demkow, Urszula, Skopiński, Piotr, Skopińska-Różewska, Ewa, Lewicki, Sławomir, Zdanowski, Robert, COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, and Pokorski, Mieczyslaw, editor

Published
2017
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39. Isolated Hearing Impairment Caused by SPATA5 Mutations in a Family with Variable Phenotypic Expression

Author

Szczałuba, Krzysztof, Szymańska, Krystyna, Kosińska, Joanna, Pollak, Agnieszka, Murcia, Victor, Kędra, Anna, Stawiński, Piotr, Rydzanicz, Małgorzata, Demkow, Urszula, Płoski, Rafał, COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, and Pokorski, Mieczyslaw, editor

Published
2017
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40. Sensitivity of Next-Generation Sequencing Metagenomic Analysis for Detection of RNA and DNA Viruses in Cerebrospinal Fluid: The Confounding Effect of Background Contamination

Author

Bukowska-Ośko, Iwona, Perlejewski, Karol, Nakamura, Shota, Motooka, Daisuke, Stokowy, Tomasz, Kosińska, Joanna, Popiel, Marta, Płoski, Rafał, Horban, Andrzej, Lipowski, Dariusz, Caraballo Cortés, Kamila, Pawełczyk, Agnieszka, Demkow, Urszula, Stępień, Adam, Radkowski, Marek, Laskus, Tomasz, Cohen, Irun R., Series editor, Lajtha, N. S. Abel, Series editor, Lambris, John D., Series editor, Paoletti, Rodolfo, Series editor, and Pokorski, Mieczyslaw, Series editor

Published
2017
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47. Metagenomic Analysis of Cerebrospinal Fluid from Patients with Multiple Sclerosis

Author

Perlejewski, Karol, Bukowska-Ośko, Iwona, Nakamura, Shota, Motooka, Daisuke, Stokowy, Tomasz, Płoski, Rafał, Rydzanicz, Małgorzata, Zakrzewska-Pniewska, Beata, Podlecka-Piętowska, Aleksandra, Nojszewska, Monika, Gogol, Anna, Caraballo Cortés, Kamila, Demkow, Urszula, Stępień, Adam, Laskus, Tomasz, Radkowski, Marek, and Pokorski, Mieczyslaw, editor

Published
2016
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