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Ou L, Lin H, Song Y, et al. Int J Nanomedicine. 2020;15:5131–5146. The Editor and Publisher of International Journal of Nanomedicine are retracting the published article. The authors requested to correct the image used for Figure 8D, p-PTEN, Inhibitor, however it was found the image had been duplicated with that from Figure 7E, p-PTEN, inhibitor from Ou L, Sun T, Liu M, et al. Efficient miRNA Inhibitor Delivery with Graphene Oxide-Polyethylenimine to Inhibit Oral Squamous Cell Carcinoma. Int J Nanomedicine. 2020;15:1569–1583. https://doi.org/10.2147/IJN.S220057. The authors cooperated with our queries and provided some data from their study, but they were unable to provide a satisfactory explanation for the image duplication. As the findings could not be adequately verified the Editor and Publisher made the decision to retract the article. The authors did not agree with this decision. We have been informed in our decision-making by our editorial policies and the COPE guidelines. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

Lingling Ou,1 Haiyingjie Lin,2 Yuwei Song,1 Guoqiang Tan,1 Xiujuan Gui,1 Jinyuan Li,1 Xiaoting Chen,3 Zhendong Deng,3 Shaoqiang Lin1,3 1Department of Stomatology, The First Affiliated Hospital of Jinan University, Guangzhou 510632, People’s Republic of China; 2Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, People’s Republic of China; 3Integrated Traditional and Western Medicine Research Center of the First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510000, People’s Republic of ChinaCorrespondence: Lingling OuThe First Affiliated Hospital of Jinan University, No. 613 West Huangpu Avenue, Guangzhou 510632, People’s Republic of ChinaEmail oulingling123@126.comShaoqiang LinIntegrated Traditional and Western Medicine Research Center of the First Affiliated Hospital of Guangdong Pharmaceutical University, No. 19 Nonglinxia Road, Guangzhou 510000, People’s Republic of ChinaEmail tlshq@jnu.edu.cnBackground: Gene therapy is considered a novel way to treat osteosarcoma, and microRNAs are potential therapeutic targets for osteosarcoma. miR-214 has been found to promote osteosarcoma aggression and metastasis. Graphene oxide (GO) is widely used for gene delivery for the distinct physiochemical properties and minimal cytotoxicity.Methods: Polyethyleneimine (PEI)-functionalized GO complex was well-prepared and loaded with miR-214 inhibitor at different concentrations. The load efficacy was tested by gel retardation assay and the cy3-labeled fluorescence of cellular uptake. The experiments of wound healing, immunofluorescence staining, Western blot, qRT-PCR and immunohistochemical staining were performed to measure the inhibitory effect of the miR-214 inhibitor systematically released from the complexes against MG63, U2OS cells and xenograft tumors.Results: The systematic mechanistic elucidation of the efficient delivery of the miR-214 inhibitor by

This paper has been retracted. Ou L, Lin H, Song Y, et al. Int J Nanomedicine. 2020;15:5131–5146. The Editor and Publisher of International Journal of Nanomedicine are retracting the published article. The authors requested to correct the image used for Figure 8D, p-PTEN, Inhibitor, however it was found the image had been duplicated with that from Figure 7E, p-PTEN, inhibitor from Ou L, Sun T, Liu M, et al. Efficient miRNA Inhibitor Delivery with Graphene Oxide-Polyethylenimine to Inhibit Oral Squamous Cell Carcinoma. Int J Nanomedicine. 2020;15:1569–1583. https://doi.org/10.2147/IJN.S220057. The authors cooperated with our queries and provided some data from their study, but they were unable to provide a satisfactory explanation for the image duplication. As the findings could not be adequately verified the Editor and Publisher made the decision to retract the article. The authors did not agree with this decision. We have been informed in our decision-making by our editorial policies and the COPE guidelines. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.