846 results on '"Denu, John M."'
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2. The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse
3. Intrinsic catalytic properties of histone H3 lysine-9 methyltransferases preserve monomethylation levels under low S-adenosylmethionine
4. Sirt6 regulates lifespan in Drosophila melanogaster
5. The role of ATP citrate lyase in myelin formation and maintenance.
6. Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association
7. Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice
8. Catalysis by protein acetyltransferase Gcn5
9. Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity
10. A practical guide for analysis of histone post-translational modifications by mass spectrometry: Best practices and pitfalls
11. Metabolism and the Epigenome: A Dynamic Relationship
12. Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators
13. Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence
14. PD35-07 IDENTIFYING AND TARGETING UPREGULATED HISTONE MODIFYING ENZYMES INVOLVED IN PROSTATE CANCER CELL SURVIVAL AFTER ANDROGEN DEPRIVATION THERAPY
15. Mechanism of activation for the sirtuin 6 protein deacylase
16. Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism
17. Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway
18. Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic β-cells
19. Dietary restriction of individual amino acids stimulates unique molecular responses in mouse liver
20. Nucleic acid sequence contributes to remodeler-mediated targeting of histone H2A.Z
21. Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions
22. General method for rapid purification of native chromatin fragments
23. Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys
24. Circadian Control of Fatty Acid Elongation by SIRT1 Protein-mediated Deacetylation of Acetyl-coenzyme A Synthetase 1*
25. Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy
26. DOT1L is a barrier to histone acetylation during reprogramming to pluripotency
27. Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide Activated Sirtuin 7
28. Protein restriction slows the development and progression of Alzheimer's disease in mice
29. Using comparative biology to understand how aging affects mitochondrial metabolism
30. Metabolic programming of the epigenome: host and gut microbial metabolite interactions with host chromatin
31. Chemical signaling between gut microbiota and host chromatin: What is your gut really saying?
32. Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6
33. Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model
34. EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis
35. Crystal Structure of the Dual Specificity Protein Phosphatase VHR
36. Visualization of Intermediate and Transition-State Structures in Protein-Tyrosine Phosphatase Catalysis
37. Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells
38. Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis
39. A Novel Quantitative Mass Spectrometry Platform for Determining Protein O-GlcNAcylation Dynamics
40. Mechanisms and Dynamics of Protein Acetylation in Mitochondria
41. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies
42. Site-Specific Lysine Acetylation Stoichiometry Across Subcellular Compartments
43. Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk
44. Data from NUP98–PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to Inhibition of PHD Histone Reader Function
45. Supplementary Tables S1-S10 from NUP98–PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to Inhibition of PHD Histone Reader Function
46. Supplementary Methods and Figures from NUP98–PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to Inhibition of PHD Histone Reader Function
47. SIRT3 Mediates Multi-Tissue Coupling for Metabolic Fuel Switching
48. Environmental Impact on Epigenetic Histone Language
49. Acss2 Deletion Reveals Functional Versatility via Tissue-Specific Roles in Transcriptional Regulation
50. Acss2 Deletion Reveals Functional Versatility via Tissue-Specific Roles in Transcriptional Regulation
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