Author: "Dept Stat" - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"Dept Stat"' showing total 82 results

Start Over Author "Dept Stat"

82 results on '"Dept Stat"'

1. A second generation human haplotype map of over 3.1 million SNPs

Author: Univ Michigan, Dept Biostat, Ctr Stat Genet, Ann Arbor, MI 48109 USA, Univ Oxford, Dept Stat, Oxford OX1 3TG, England, Scripps Res Inst, La Jolla, CA 92037 USA, Perlegen Sci Inc, Mountain View, CA 94043 USA, Baylor Coll Med, Dept Mol & Human Genet, Human Genome Sequencing Ctr, Houston, TX 77030 USA, Affymetrix Inc, Santa Clara, CA 95051 USA, Pacific Biosci, Menlo Pk, CA 94025 USA, Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA, Harvard Univ, Broad Inst, Cambridge, MA 02139 USA, MIT, Cambridge, MA 02139 USA, Chinese Acad Sci, Beijing Genom Inst, Beijing 100300, Peoples R China, Massachusetts Gen Hosp, Boston, MA 02114 USA, Harvard Univ, Sch Med, Simches Res Ctr, Boston, MA 02114 USA, Chinese Natl Human Genome Ctr, Beijing Econ Technol Dev Area, Beijing 100176, Peoples R China, Chinese Natl Human Genome Ctr, Shanghai 201203, Peoples R China, Fudan Univ, Shanghai 201203, Peoples R China, CAS, SIBS, Sch Life Sci, MPG Partner Inst Computat Biol, Shanghai 201203, Peoples R China, Chinese Univ Hong Kong, Dept Biochem, Croucher Lab Human Genet, Shatin, Hong Kong, Peoples R China, Hong Kong Univ Sci & Technol, Dept Biochem, Kowloon, Hong Kong, Peoples R China, Hong Kong Univ Sci & Technol, Appl Genom Ctr, Kowloon, Hong Kong, Peoples R China, Illumina, San Diego, CA 92121 USA, Complete Genom Inc, Sunnyvale, CA 94085 USA, Prognosys Biosci Inc, San Diego, CA 92121 USA, McGill Univ, Montreal, PQ H3A 1A4, Canada, Genome Quebec Innovat Ctr, Montreal, PQ H3A 1A4, Canada, Univ Montreal, Publ Law Res Ctr, Downtown Stn, Montreal, PQ H3C 3J7, Canada, Ontario Inst Canc Res, MaRS Ctr, Toronto, ON M5G 1L7, Canada, Univ Calif San Francisco, Cardiovasc Res Inst, San Francisco, CA 94143 USA, Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA, Univ Hong Kong, Genome Res Ctr, Hong Kong, Hong Kong, Peoples R China, Univ Tokyo, Inst Med Sci, Minato Ku, Tokyo 1088639, Japan, RIKEN SNP Res Ctr, Tsurumi Ku, Kanagawa 2300045, Japan, Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England, Univ Cambridge, Dept Oncol, Cambridge CB1 8RN, England, Solexa Ltd, Saffron Walden CB10 1XL, Essex, England, Columbia Univ, New York, NY 10027 USA, Univ Leicester, Dept Genet, Leicester LE1 7RH, Leics, England, Johns Hopkins Univ, Sch Med, McKusick Nathans Inst Genet Med, Baltimore, MD 21205 USA, Int Epidemiol Inst, Rockville, MD 20850 USA, Univ Calif Santa Cruz, Ctr Biomol Sci & Engn, Santa Cruz, CA 95064 USA, Univ Chicago, Dept Stat, Chicago, IL 60637 USA, Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA, Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England, Univ Washington, Dept Biostat, Seattle, WA 98195 USA, NHGRI, US NIH, Bethesda, MD 20892 USA, Natl Lib Med, US NIH, Natl Ctr Biotechnol Informat, Bethesda, MD 20894 USA, Univ Chicago, Dept Med, Med Genet Sect, Chicago, IL 60637 USA, Beijing Normal Univ, Beijing 100875, Peoples R China, Hlth Sci Univ Hokkaido, Ishikari, Hokkaido 0610293, Japan, Shinshu Univ, Sch Med, Dept Med Genet, Matsumoto, Nagano 3908621, Japan, UNESCO Bangkok, Bangkok 10110, Thailand, Univ Tsukuba, Eubios Eth Inst, Tsukuba, Ibaraki 3058691, Japan, Howard Univ, Natl Human Genome Ctr, Washington, DC 20059 USA, Univ Ibadan, Coll Med, Ibadan, Oyo State, Nigeria, Case Western Reserve Univ, Sch Med, Dept Bioeth, Cleveland, OH 44106 USA, Univ Utah, Dept Human Genet, Eccles Inst Human Genet, Salt Lake City, UT 84112 USA, Chinese Acad Social Sci, Inst Philosophy, Ctr Appl Eth, Beijing 100067, Peoples R China, Genet Interest Grp, London N13 0P, England, Kyoto Univ, Inst Res Humanities, Kyoto 6068501, Japan, Grad Sch Biostudies, Sakyo Ku, Kyoto 6068501, Japan, Nagasaki Univ, Grad Sch Biomed Sci, Dept Human Genet, Nagasaki 8528523, Japan, Univ Oklahoma, Dept Anthropol, Norman, OK 73019 USA, Vanderbilt Univ, Ctr Genet & Hlth Policy, Nashville, TN 37232 USA, Wellcome Trust Res Labs, London NW1 2BE, England, Washington Univ, Sch Med, Genome Sequencing Ctr, St Louis, MO 63108 USA, Chinese Acad Sci, Beijing 100864, Peoples R China, Genome Canada, Ottawa, ON K2P 1P1, Canada, McGill Univ, Off Technol Transfer, Montreal, PQ H3A 2A7, Canada, Genome Quebec, Montreal, PQ H3B 1S6, Canada, Minist Educ Culture Sports Sci & Technol, Chiyoda Ku, Tokyo 1008959, Japan, Minist Sci & Technol, Beijing 100862, Peoples R China, Human Genet Resource Adm China, Beijing 100081, Peoples R China, US NIH, Off Behav & Social Sci Res, Bethesda, MD 20892 USA, Novartis Pharmaceut Corp, Biomarker Dev, E Hanover, NJ 07936 USA, US NIH, Off Technol Transfer, Rockville, MD 20852 USA, Univ Maryland, Sch Law, Baltimore, MD 21201 USA, Mjdaly@chgr.mgh.harvard.edu; mcvean@stats.ox.ac.uk, Frazer, Kelly A., Ballinger, Dennis G., Cox, David R., Hinds, David A., Stuve, Laura L., Gibbs, Richard A., Belmont, John W., Boudreau, Andrew, Hardenbol, Paul, Leal, Suzanne M., Pasternak, Shiran, Tanaka, Toshihiro, Tsunoda, Tatsuhiko, Deloukas, Panos, Bird, Christine P., Delgado, Marcos, Dermitzakis, Emmanouil T., Gwilliam, Rhian, Hunt, Sarah, Morrison, Jonathan, Powell, Don, Wheeler, David A., Stranger, Barbara E., Whittaker, Pamela, Bentley, David R., Daly, Mark J., De Bakker, Paul I.W., Barrett, Jeff, Chretien, Yves R., Maller, Julian, McCarroll, Steve, Patterson, Nick, Willis, Thomas D., Pe'er, Itsik, Price, Alkes, Purcell, Shaun, Richter, Daniel J., Sabeti, Pardis, Saxena, Richa, Schaffner, Stephen F., Sham, Pak C., Varilly, Patrick, Altshuler, David, Yu, Fuli, Stein, Lincoln D., Krishnan, Lalitha, Smith, Albert Vernon, Tello-Ruiz, Marcela K., Thorisson, Gudmundur A., Chakravarti, Aravinda, Chen, Peter E., Cutler, David J., Kashuk, Carl S., Lin, Shin, Yang, Huanming, Abecasis, Gon??alo R., Guan, Weihua, Li, Yun, Munro, Heather M., Qin, Zhaohui Steve, Thomas, Daryl J., McVean, Gilean, Auton, Adam, Bottolo, Leonardo, Cardin, Niall, Zeng, Changqing, Eyheramendy, Susana, Freeman, Colin, Marchini, Jonathan, Myers, Simon, Spencer, Chris, Stephens, Matthew, Donnelly, Peter, Cardon, Lon R., Clarke, Geraldine, Evans, David M., Gao, Yang, Morris, Andrew P., Weir, Bruce S., Johnson, Todd A., Mullikin, James C., Sherry, Stephen T., Feolo, Michael, Skol, Andrew, Hu, Haoran, Hu, Weitao, Li, Chaohua, Lin, Wei, Liu, Siqi, Pan, Hao, Tang, Xiaoli, Wang, Jian, Wang, Wei, Yu, Jun, Zhang, Bo, Zhang, Qingrun, Zhao, Hongbin, Zhao, Hui, Zhou, Jun, Gabriel, Stacey B., Barry, Rachel, Blumenstiel, Brendan, Camargo, Amy, Defelice, Matthew, Faggart, Maura, Goyette, Mary, Gupta, Supriya, Moore, Jamie, Nguyen, Huy, Onofrio, Robert C., Parkin, Melissa, Roy, Jessica, Stahl, Erich, Winchester, Ellen, Ziaugra, Liuda, Shen, Yan, Yao, Zhijian, Huang, Wei, Chu, Xun, He, Yungang, Jin, Li, Liu, Yangfan, Shen, Yayun, Sun, Weiwei, Wang, Haifeng, Wang, Yi, Wang, Ying, Xiong, Xiaoyan, Xu, Liang, Waye, Mary M.Y., Tsui, Stephen K.W., Wong, J. Tze-Fei, Galver, Luana M., Fan, Jian-Bing, Gunderson, Kevin, Murray, Sarah S., Oliphant, Arnold R., Chee, Mark S., Montpetit, Alexandre, Chagnon, Fanny, Ferretti, Vincent, Leboeuf, Martin, Olivier, Jean-Franccois, Phillips, Michael S., Roumy, Stephanie, Sallee, Clementine, Verner, Andrei, Hudson, Thomas J., Kwok, Pui-Yan, Cai, Dongmei, Koboldt, Daniel C., Miller, Raymond D., Pawlikowska, Ludmila, Taillon-Miller, Patricia, Xiao, Ming, Tsui, Lap-Chee, Mak, William, Song, You Qiang, Tam, Paul K.H., Nakamura, Yusuke, Kawaguchi, Takahisa, Kitamoto, Takuya, Morizono, Takashi, Nagashima, Atsushi, Ohnishi, Yozo, Sekine, Akihiro, Univ Michigan, Dept Biostat, Ctr Stat Genet, Ann Arbor, MI 48109 USA, Univ Oxford, Dept Stat, Oxford OX1 3TG, England, Scripps Res Inst, La Jolla, CA 92037 USA, Perlegen Sci Inc, Mountain View, CA 94043 USA, Baylor Coll Med, Dept Mol & Human Genet, Human Genome Sequencing Ctr, Houston, TX 77030 USA, Affymetrix Inc, Santa Clara, CA 95051 USA, Pacific Biosci, Menlo Pk, CA 94025 USA, Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA, Harvard Univ, Broad Inst, Cambridge, MA 02139 USA, MIT, Cambridge, MA 02139 USA, Chinese Acad Sci, Beijing Genom Inst, Beijing 100300, Peoples R China, Massachusetts Gen Hosp, Boston, MA 02114 USA, Harvard Univ, Sch Med, Simches Res Ctr, Boston, MA 02114 USA, Chinese Natl Human Genome Ctr, Beijing Econ Technol Dev Area, Beijing 100176, Peoples R China, Chinese Natl Human Genome Ctr, Shanghai 201203, Peoples R China, Fudan Univ, Shanghai 201203, Peoples R China, CAS, SIBS, Sch Life Sci, MPG Partner Inst Computat Biol, Shanghai 201203, Peoples R China, Chinese Univ Hong Kong, Dept Biochem, Croucher Lab Human Genet, Shatin, Hong Kong, Peoples R China, Hong Kong Univ Sci & Technol, Dept Biochem, Kowloon, Hong Kong, Peoples R China, Hong Kong Univ Sci & Technol, Appl Genom Ctr, Kowloon, Hong Kong, Peoples R China, Illumina, San Diego, CA 92121 USA, Complete Genom Inc, Sunnyvale, CA 94085 USA, Prognosys Biosci Inc, San Diego, CA 92121 USA, McGill Univ, Montreal, PQ H3A 1A4, Canada, Genome Quebec Innovat Ctr, Montreal, PQ H3A 1A4, Canada, Univ Montreal, Publ Law Res Ctr, Downtown Stn, Montreal, PQ H3C 3J7, Canada, Ontario Inst Canc Res, MaRS Ctr, Toronto, ON M5G 1L7, Canada, Univ Calif San Francisco, Cardiovasc Res Inst, San Francisco, CA 94143 USA, Washington Univ, Sch Med, Dept Genet, St Louis, MO 63110 USA, Univ Hong Kong, Genome Res Ctr, Hong Kong, Hong Kong, Peoples R China, Univ Tokyo, Inst Med Sci, Minato Ku, Tokyo 1088639, Japan, RIKEN SNP Res Ctr, Tsurumi Ku, Kanagawa 2300045, Japan, Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England, Univ Cambridge, Dept Oncol, Cambridge CB1 8RN, England, Solexa Ltd, Saffron Walden CB10 1XL, Essex, England, Columbia Univ, New York, NY 10027 USA, Univ Leicester, Dept Genet, Leicester LE1 7RH, Leics, England, Johns Hopkins Univ, Sch Med, McKusick Nathans Inst Genet Med, Baltimore, MD 21205 USA, Int Epidemiol Inst, Rockville, MD 20850 USA, Univ Calif Santa Cruz, Ctr Biomol Sci & Engn, Santa Cruz, CA 95064 USA, Univ Chicago, Dept Stat, Chicago, IL 60637 USA, Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA, Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England, Univ Washington, Dept Biostat, Seattle, WA 98195 USA, NHGRI, US NIH, Bethesda, MD 20892 USA, Natl Lib Med, US NIH, Natl Ctr Biotechnol Informat, Bethesda, MD 20894 USA, Univ Chicago, Dept Med, Med Genet Sect, Chicago, IL 60637 USA, Beijing Normal Univ, Beijing 100875, Peoples R China, Hlth Sci Univ Hokkaido, Ishikari, Hokkaido 0610293, Japan, Shinshu Univ, Sch Med, Dept Med Genet, Matsumoto, Nagano 3908621, Japan, UNESCO Bangkok, Bangkok 10110, Thailand, Univ Tsukuba, Eubios Eth Inst, Tsukuba, Ibaraki 3058691, Japan, Howard Univ, Natl Human Genome Ctr, Washington, DC 20059 USA, Univ Ibadan, Coll Med, Ibadan, Oyo State, Nigeria, Case Western Reserve Univ, Sch Med, Dept Bioeth, Cleveland, OH 44106 USA, Univ Utah, Dept Human Genet, Eccles Inst Human Genet, Salt Lake City, UT 84112 USA, Chinese Acad Social Sci, Inst Philosophy, Ctr Appl Eth, Beijing 100067, Peoples R China, Genet Interest Grp, London N13 0P, England, Kyoto Univ, Inst Res Humanities, Kyoto 6068501, Japan, Grad Sch Biostudies, Sakyo Ku, Kyoto 6068501, Japan, Nagasaki Univ, Grad Sch Biomed Sci, Dept Human Genet, Nagasaki 8528523, Japan, Univ Oklahoma, Dept Anthropol, Norman, OK 73019 USA, Vanderbilt Univ, Ctr Genet & Hlth Policy, Nashville, TN 37232 USA, Wellcome Trust Res Labs, London NW1 2BE, England, Washington Univ, Sch Med, Genome Sequencing Ctr, St Louis, MO 63108 USA, Chinese Acad Sci, Beijing 100864, Peoples R China, Genome Canada, Ottawa, ON K2P 1P1, Canada, McGill Univ, Off Technol Transfer, Montreal, PQ H3A 2A7, Canada, Genome Quebec, Montreal, PQ H3B 1S6, Canada, Minist Educ Culture Sports Sci & Technol, Chiyoda Ku, Tokyo 1008959, Japan, Minist Sci & Technol, Beijing 100862, Peoples R China, Human Genet Resource Adm China, Beijing 100081, Peoples R China, US NIH, Off Behav & Social Sci Res, Bethesda, MD 20892 USA, Novartis Pharmaceut Corp, Biomarker Dev, E Hanover, NJ 07936 USA, US NIH, Off Technol Transfer, Rockville, MD 20852 USA, Univ Maryland, Sch Law, Baltimore, MD 21201 USA, Mjdaly@chgr.mgh.harvard.edu; mcvean@stats.ox.ac.uk, Frazer, Kelly A., Ballinger, Dennis G., Cox, David R., Hinds, David A., Stuve, Laura L., Gibbs, Richard A., Belmont, John W., Boudreau, Andrew, Hardenbol, Paul, Leal, Suzanne M., Pasternak, Shiran, Tanaka, Toshihiro, Tsunoda, Tatsuhiko, Deloukas, Panos, Bird, Christine P., Delgado, Marcos, Dermitzakis, Emmanouil T., Gwilliam, Rhian, Hunt, Sarah, Morrison, Jonathan, Powell, Don, Wheeler, David A., Stranger, Barbara E., Whittaker, Pamela, Bentley, David R., Daly, Mark J., De Bakker, Paul I.W., Barrett, Jeff, Chretien, Yves R., Maller, Julian, McCarroll, Steve, Patterson, Nick, Willis, Thomas D., Pe'er, Itsik, Price, Alkes, Purcell, Shaun, Richter, Daniel J., Sabeti, Pardis, Saxena, Richa, Schaffner, Stephen F., Sham, Pak C., Varilly, Patrick, Altshuler, David, Yu, Fuli, Stein, Lincoln D., Krishnan, Lalitha, Smith, Albert Vernon, Tello-Ruiz, Marcela K., Thorisson, Gudmundur A., Chakravarti, Aravinda, Chen, Peter E., Cutler, David J., Kashuk, Carl S., Lin, Shin, Yang, Huanming, Abecasis, Gon??alo R., Guan, Weihua, Li, Yun, Munro, Heather M., Qin, Zhaohui Steve, Thomas, Daryl J., McVean, Gilean, Auton, Adam, Bottolo, Leonardo, Cardin, Niall, Zeng, Changqing, Eyheramendy, Susana, Freeman, Colin, Marchini, Jonathan, Myers, Simon, Spencer, Chris, Stephens, Matthew, Donnelly, Peter, Cardon, Lon R., Clarke, Geraldine, Evans, David M., Gao, Yang, Morris, Andrew P., Weir, Bruce S., Johnson, Todd A., Mullikin, James C., Sherry, Stephen T., Feolo, Michael, Skol, Andrew, Hu, Haoran, Hu, Weitao, Li, Chaohua, Lin, Wei, Liu, Siqi, Pan, Hao, Tang, Xiaoli, Wang, Jian, Wang, Wei, Yu, Jun, Zhang, Bo, Zhang, Qingrun, Zhao, Hongbin, Zhao, Hui, Zhou, Jun, Gabriel, Stacey B., Barry, Rachel, Blumenstiel, Brendan, Camargo, Amy, Defelice, Matthew, Faggart, Maura, Goyette, Mary, Gupta, Supriya, Moore, Jamie, Nguyen, Huy, Onofrio, Robert C., Parkin, Melissa, Roy, Jessica, Stahl, Erich, Winchester, Ellen, Ziaugra, Liuda, Shen, Yan, Yao, Zhijian, Huang, Wei, Chu, Xun, He, Yungang, Jin, Li, Liu, Yangfan, Shen, Yayun, Sun, Weiwei, Wang, Haifeng, Wang, Yi, Wang, Ying, Xiong, Xiaoyan, Xu, Liang, Waye, Mary M.Y., Tsui, Stephen K.W., Wong, J. Tze-Fei, Galver, Luana M., Fan, Jian-Bing, Gunderson, Kevin, Murray, Sarah S., Oliphant, Arnold R., Chee, Mark S., Montpetit, Alexandre, Chagnon, Fanny, Ferretti, Vincent, Leboeuf, Martin, Olivier, Jean-Franccois, Phillips, Michael S., Roumy, Stephanie, Sallee, Clementine, Verner, Andrei, Hudson, Thomas J., Kwok, Pui-Yan, Cai, Dongmei, Koboldt, Daniel C., Miller, Raymond D., Pawlikowska, Ludmila, Taillon-Miller, Patricia, Xiao, Ming, Tsui, Lap-Chee, Mak, William, Song, You Qiang, Tam, Paul K.H., Nakamura, Yusuke, Kawaguchi, Takahisa, Kitamoto, Takuya, Morizono, Takashi, Nagashima, Atsushi, Ohnishi, Yozo, and Sekine, Akihiro
Abstract: We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and includes 25-35% of common SNP variation in the populations surveyed. The map is estimated to capture untyped common variation with an average maximum r(2) of between 0.9 and 0.96 depending on population. We demonstrate that the current generation of commercial genome-wide genotyping products captures common Phase II SNPs with an average maximum r(2) of up to 0.8 in African and up to 0.95 in non-African populations, and that potential gains in power in association studies can be obtained through imputation. These data also reveal novel aspects of the structure of linkage disequilibrium. We show that 10-30% of pairs of individuals within a population share at least one region of extended genetic identity arising from recent ancestry and that up to 1% of all common variants are untaggable, primarily because they lie within recombination hotspots. We show that recombination rates vary systematically around genes and between genes of different function. Finally, we demonstrate increased differentiation at non-synonymous, compared to synonymous, SNPs, resulting from systematic differences in the strength or efficacy of natural selection between populations.
Published: 2009

2. A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia.

Author: [ 1 ] Copenhagen Univ Hosp, Res Inst Biol Psychiat, Mental Hlth Ctr Sct Hans, DK-4000 Roskilde, Denmark [ 2 ] Univ Munich, Div Mol & Clin Neurobiol, D-80336 Munich, Germany [ 3 ] Univ Munich, Dept Psychiat, D-80336 Munich, Germany [ 4 ] Univ Bonn, Dept Genom, Life & Brain Ctr, D-53127 Bonn, Germany [ 5 ] Univ Bonn, Inst Human Genet, D-53111 Bonn, Germany [ 6 ] Univ Copenhagen, Ctr Pharmacogen, DK-2200 Copenhagen, Denmark [ 7 ] Aalborg Psychiat Hosp, Unit Psychiat Res, DK-9000 Aalborg, Denmark [ 8 ] Univ Copenhagen Hosp, Clin Pharmacol Unit, DK-2400 Bispebjerg, Denmark [ 9 ] GlaxoSmithKline R&D, Med Genet, I-37135 Verona, Italy [ 10 ] Univ Med Ctr Utrecht, Dept Psychiat, Rudolf Magnus Inst Neurosci, NL-3584 CG Utrecht, Netherlands [ 11 ] Univ Med Ctr Utrecht, Dept Med Genet, NL-3584 CG Utrecht, Netherlands [ 12 ] Univ Oslo, Inst Psychiat, N-0407 Oslo, Norway [ 13 ] Oslo Univ Hosp Ulleval, Dept Med Genet, N-0407 Oslo, Norway [ 14 ] Oslo Univ Hosp Ulleval, Dept Psychiat, N-0407 Oslo, Norway [ 15 ] Hadassah Hebrew Univ, Med Ctr, Dept Psychiat, Biol Psychiat Lab, IL-91120 Jerusalem, Israel [ 16 ] FIMM, Inst Mol Med, Helsinki 00290, Finland [ 17 ] Natl Inst Hlth & Welf, Dept Mental Hlth & Alcohol Res, Helsinki 00300, Finland [ 18 ] Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England [ 19 ] Univ Verona, Sect Psychiat & Clin Psychol, I-37134 Verona, Italy [ 20 ] Univ Calif Los Angeles, Dept Stat, Los Angeles, CA 90095 USA [ 21 ] Univ Heidelberg, Dept Genet Epidemiol Psychiat, Cent Inst Mental Hlth, D-68159 Mannheim, Germany [ 22 ] Cardiff Univ, Sch Med, Dept Psychol Med & Neurol, MRC Ctr Neuropsychiat Genet & Genom, Cardiff CF14 4XN, S Glam, Wales [ 23 ] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England [ 24 ] Broad Inst, Cambridge, MA 02142 USA [ 25 ] Univ Aberdeen, Dept Mental Hlth, Aberdeen AB25 2ZD, Scotland [ 26 ] Univ Calif Los Angeles, Ctr Neurobehav Genet, Los Angeles, CA 90095 USA [ 27 ] Dept Human Genet, Los Angeles, CA 90095 USA [ 28, Ingason, Andrés, Giegling, Ina, Cichon, Sven, Hansen, Thomas, Rasmussen, Henrik B, Nielsen, Jimmi, Jürgens, Gesche, Muglia, Pierandrea, Hartmann, Annette M, Strengman, Eric, Vasilescu, Catalina, Mühleisen, Thomas W, Djurovic, Srdjan, Melle, Ingrid, Lerer, Bernard, Möller, Hans-Jürgen, Francks, Clyde, Pietiläinen, Olli P H, Lonnqvist, Jouko, Suvisaari, Jaana, Tuulio-Henriksson, Annamari, Walshe, Muriel, Vassos, Evangelos, Di Forti, Marta, Murray, Robin, Bonetto, Chiara, Tosato, Sarah, Cantor, Rita M, Rietschel, Marcella, Craddock, Nick, Owen, Michael J, Peltonen, Leena, Andreassen, Ole A, Nöthen, Markus M, St Clair, David, Ophoff, Roel A, O'Donovan, Michael C, Collier, David A, Werge, Thomas, Rujescu, Dan, [ 1 ] Copenhagen Univ Hosp, Res Inst Biol Psychiat, Mental Hlth Ctr Sct Hans, DK-4000 Roskilde, Denmark [ 2 ] Univ Munich, Div Mol & Clin Neurobiol, D-80336 Munich, Germany [ 3 ] Univ Munich, Dept Psychiat, D-80336 Munich, Germany [ 4 ] Univ Bonn, Dept Genom, Life & Brain Ctr, D-53127 Bonn, Germany [ 5 ] Univ Bonn, Inst Human Genet, D-53111 Bonn, Germany [ 6 ] Univ Copenhagen, Ctr Pharmacogen, DK-2200 Copenhagen, Denmark [ 7 ] Aalborg Psychiat Hosp, Unit Psychiat Res, DK-9000 Aalborg, Denmark [ 8 ] Univ Copenhagen Hosp, Clin Pharmacol Unit, DK-2400 Bispebjerg, Denmark [ 9 ] GlaxoSmithKline R&D, Med Genet, I-37135 Verona, Italy [ 10 ] Univ Med Ctr Utrecht, Dept Psychiat, Rudolf Magnus Inst Neurosci, NL-3584 CG Utrecht, Netherlands [ 11 ] Univ Med Ctr Utrecht, Dept Med Genet, NL-3584 CG Utrecht, Netherlands [ 12 ] Univ Oslo, Inst Psychiat, N-0407 Oslo, Norway [ 13 ] Oslo Univ Hosp Ulleval, Dept Med Genet, N-0407 Oslo, Norway [ 14 ] Oslo Univ Hosp Ulleval, Dept Psychiat, N-0407 Oslo, Norway [ 15 ] Hadassah Hebrew Univ, Med Ctr, Dept Psychiat, Biol Psychiat Lab, IL-91120 Jerusalem, Israel [ 16 ] FIMM, Inst Mol Med, Helsinki 00290, Finland [ 17 ] Natl Inst Hlth & Welf, Dept Mental Hlth & Alcohol Res, Helsinki 00300, Finland [ 18 ] Kings Coll London, Inst Psychiat, Div Psychol Med, London SE5 8AF, England [ 19 ] Univ Verona, Sect Psychiat & Clin Psychol, I-37134 Verona, Italy [ 20 ] Univ Calif Los Angeles, Dept Stat, Los Angeles, CA 90095 USA [ 21 ] Univ Heidelberg, Dept Genet Epidemiol Psychiat, Cent Inst Mental Hlth, D-68159 Mannheim, Germany [ 22 ] Cardiff Univ, Sch Med, Dept Psychol Med & Neurol, MRC Ctr Neuropsychiat Genet & Genom, Cardiff CF14 4XN, S Glam, Wales [ 23 ] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England [ 24 ] Broad Inst, Cambridge, MA 02142 USA [ 25 ] Univ Aberdeen, Dept Mental Hlth, Aberdeen AB25 2ZD, Scotland [ 26 ] Univ Calif Los Angeles, Ctr Neurobehav Genet, Los Angeles, CA 90095 USA [ 27 ] Dept Human Genet, Los Angeles, CA 90095 USA [ 28, Ingason, Andrés, Giegling, Ina, Cichon, Sven, Hansen, Thomas, Rasmussen, Henrik B, Nielsen, Jimmi, Jürgens, Gesche, Muglia, Pierandrea, Hartmann, Annette M, Strengman, Eric, Vasilescu, Catalina, Mühleisen, Thomas W, Djurovic, Srdjan, Melle, Ingrid, Lerer, Bernard, Möller, Hans-Jürgen, Francks, Clyde, Pietiläinen, Olli P H, Lonnqvist, Jouko, Suvisaari, Jaana, Tuulio-Henriksson, Annamari, Walshe, Muriel, Vassos, Evangelos, Di Forti, Marta, Murray, Robin, Bonetto, Chiara, Tosato, Sarah, Cantor, Rita M, Rietschel, Marcella, Craddock, Nick, Owen, Michael J, Peltonen, Leena, Andreassen, Ole A, Nöthen, Markus M, St Clair, David, Ophoff, Roel A, O'Donovan, Michael C, Collier, David A, Werge, Thomas, and Rujescu, Dan
Abstract: The Abelson helper integration site 1 (AHI1) gene locus on chromosome 6q23 is among a group of candidate loci for schizophrenia susceptibility that were initially identified by linkage followed by linkage disequilibrium mapping, and subsequent replication of the association in an independent sample. Here, we present results of a replication study of AHI1 locus markers, previously implicated in schizophrenia, in a large European sample (in total 3907 affected and 7429 controls). Furthermore, we perform a meta-analysis of the implicated markers in 4496 affected and 18,920 controls. Both the replication study of new samples and the meta-analysis show evidence for significant overrepresentation of all tested alleles in patients compared with controls (meta-analysis; P = 8.2 x 10(-5)-1.7 x 10(-3), common OR = 1.09-1.11). The region contains two genes, AHI1 and C6orf217, and both genes-as well as the neighbouring phosphodiesterase 7B (PDE7B)-may be considered candidates for involvement in the genetic aetiology of schizophrenia.

3. Impact of Regressand Stratification in Dataset Shift Caused by Cross-Validation

Author: José Luis Romero Béjar, José A. Sáez, [Saez, Jose A.] Univ Granada, Dept Stat & Operat Res, Fuentenueva S-N, Granada 18071, Spain, [Romero-Bejar, Jose L.] Univ Granada, Dept Stat & Operat Res, Fuentenueva S-N, Granada 18071, Spain, [Romero-Bejar, Jose L.] IbsGRANADA Inst Invest Biosanitaria, Granada 18012, Spain, [Romero-Bejar, Jose L.] Univ Granada, IMAG Inst Math, Ventanilla 11, Granada 18001, Spain, MCIU/AEI/ERDF, UE, ERDF Operational Programme 2014-2020, Economy and Knowledge Council of the Regional Government of Andalusia, Spain, and MCIN/AEI
Subjects: Covariate shift, Tests, General Mathematics, cross-validation, dataset shift, target shift, stratification, regression, Tutorial, Computer Science (miscellaneous), Adaptation, Networks, Selection, Engineering (miscellaneous), Model
Abstract: Data that have not been modeled cannot be correctly predicted. Under this assumption, this research studies how k-fold cross-validation can introduce dataset shift in regression problems. This fact implies data distributions in the training and test sets to be different and, therefore, a deterioration of the model performance estimation. Even though the stratification of the output variable is widely used in the field of classification to reduce the impacts of dataset shift induced by cross-validation, its use in regression is not widespread in the literature. This paper analyzes the consequences for dataset shift of including different regressand stratification schemes in cross-validation with regression data. The results obtained show that these allow for creating more similar training and test sets, reducing the presence of dataset shift related to cross-validation. The bias and deviation of the performance estimation results obtained by regression algorithms are improved using the highest amounts of strata, as are the number of cross-validation repetitions necessary to obtain these better results., MCIU/AEI/ERDF, UE PGC2018098860-B-I00, ERDF Operational Programme 2014-2020, Economy and Knowledge Council of the Regional Government of Andalusia, Spain MCIN/AEI CEX2020-001105-M A-FQM-345-UGR18
Published: 2022
Full Text: View/download PDF

4. On the Suitability of Bagging-Based Ensembles with Borderline Label Noise

Author: José Luis Romero Béjar, José A. Sáez, [Saez, Jose A.] Univ Granada, Dept Stat & Operat Res, Fuentenueva S-N, E-18071 Granada, Spain, [Romero-Bejar, Jose L.] Univ Granada, Dept Stat & Operat Res, Fuentenueva S-N, E-18071 Granada, Spain, [Romero-Bejar, Jose L.] Inst Invest Biosanitaria IbsGRANADA, Granada 18012, Spain, [Romero-Bejar, Jose L.] Univ Granada IMAG, Inst Math, Ventanilla 11, Granada 18001, Spain, MCIU/AEI/ERDF, UE, ERDF Operational Programme 2014-2020, Economy and Knowledge Council of the Regional Government of Andalusia, Spain, and MCIN/AEI
Subjects: Classifiers, General Mathematics, Decision trees, Machine, borderline noise, label noise, bagging, ensembles, robust learners, classification, Complexity-measures, Robust learners, Classification, Label noise, Robust, Bagging, Borderline noise, Computer Science (miscellaneous), Ranking, Ensembles, Engineering (miscellaneous), Nonparametric statistical tests, Model
Abstract: Real-world classification data usually contain noise, which can affect the accuracy of the models and their complexity. In this context, an interesting approach to reduce the effects of noise is building ensembles of classifiers, which traditionally have been credited with the ability to tackle difficult problems. Among the alternatives to build ensembles with noisy data, bagging has shown some potential in the specialized literature. However, existing works in this field are limited and only focus on the study of noise based on a random mislabeling, which is unlikely to occur in real-world applications. Recent research shows that other types of noise, such as that occurring at class boundaries, are more common and challenging for classification algorithms. This paper delves into the analysis of the usage of bagging techniques in these complex problems, in which noise affects the decision boundaries among classes. In order to investigate whether bagging is able to reduce the impact of borderline noise, an experimental study is carried out considering a large number of datasets with different noise levels, and several noise models and classification algorithms. The results obtained reflect that bagging obtains a better accuracy and robustness than the individual models with this complex type of noise. The highest improvements in average accuracy are around 2–4% and are generally found at medium-high noise levels (from 15–20% onwards). The partial consideration of noisy samples when creating the subsamples from the original training set in bagging can make it so that only some parts of the decision boundaries among classes are impaired when building each model, reducing the impact of noise in the global system., MCIU/AEI/ERDF, UE PGC2018-098860-B-I00, ERDF Operational Programme 2014-2020 A-FQM-345-UGR18, Economy and Knowledge Council of the Regional Government of Andalusia, Spain, MCIN/AEI CEX2020-001105-M
Published: 2022
Full Text: View/download PDF

5. Preprocessing of Spectroscopic Data Using Affine Transformations to Improve Pattern-Recognition Analysis: An Application to Prehistoric Lithic Tools

Author: Francisco Javier Esquivel, José Antonio Esquivel, Antonio Morgado, José L. Romero-Béjar, Luis F. García del Moral, [Javier Esquivel, Francisco] Univ Granada, Dept Stat & Operat Res, Granada 18011, Spain, [Romero-Bejar, Jose L.] Univ Granada, Dept Stat & Operat Res, Granada 18011, Spain, [Javier Esquivel, Francisco] Univ Granada, Lab Archaeol Modelling 3D, Granada 18011, Spain, [Antonio Esquivel, Jose] Univ Granada, Lab Archaeol Modelling 3D, Granada 18011, Spain, [Antonio Esquivel, Jose] Univ Granada, Dept Prehist & Archaeol, Granada 18011, Spain, [Morgado, Antonio] Univ Granada, Dept Prehist & Archaeol, Granada 18011, Spain, [Romero-Bejar, Jose L.] Ibs GRANADA, Inst Invest Biosanitaria, Granada 18014, Spain, [Romero-Bejar, Jose L.] Univ Granada, Inst Math, IMAG, Ventanilla 11, Granada 18001, Spain, [Garcia del Moral, Luis F.] Univ Granada, Dept Plant Physiol, Granada 18011, Spain, [Garcia del Moral, Luis F.] Univ Granada, Inst Biotechnol, Granada 18011, Spain, Ministry of Economy and Competitiveness, and Junta de Andalucia
Subjects: spectroscopy, Identification, multivariate statistics, Reflectance spectroscopy, flint (chert), General Mathematics, affine transformation, archaeology, pattern recognition, Mu-m, Computer Science (miscellaneous), Engineering (miscellaneous)
Abstract: The analysis of spectral reflectance data is an important tool for obtaining relevant information about the mineral composition of objects and has been used for research in chemistry, geology, biology, archaeology, pharmacy, medicine, anthropology, and other disciplines. In archaeology, the use of spectroscopic data allows us to characterize and classify artifacts and ecofacts, to analyze patterns, and to study the exchange of materials, etc., as well as to explain some properties, such as color or post-depositional processes. The spectroscopic data are of the so-called “big data” type and must be analyzed using multivariate statistical techniques, usually principal component analysis and cluster analysis. Although there are different transformations of the raw data, in this paper, we propose preprocessing by means of an affine transformation. From a mathematical point of view, this process modifies the values of reflectance for each spectral signature scaling them into a [0, 1] interval using minimum and maximum values of reflectance, thus highlighting the features of spectral curves. This method optimizes the characteristics of amplitude and shape, reduces the influence of noise, and improves results by highlighting relevant features as peaks and valleys that may remain hidden using the raw data. This methodology has been applied to a case study of prehistoric chert (flint) artifacts retrieved in archaeological excavations in the Andévalo area located in the Archaeological Museum of Huelva (Huelva, Andalusia). The use of transformed data considerably improves the results obtained with raw data, highlighting the peaks, valleys, and the shape of spectral signatures.
Published: 2022
Full Text: View/download PDF

6. Self-Perceived Health, Life Satisfaction and Related Factors among Healthcare Professionals and the General Population: Analysis of an Online Survey, with Propensity Score Adjustment

Author: Ramón Ferri-García, María del Mar Rueda, Andrés Cabrera-León, [Ferri-Garcia, Ramon] Univ Granada, Dept Stat & Operat Res, Granada 18071, Spain, [Rueda, Maria del Mar] Univ Granada, Dept Stat & Operat Res, Granada 18071, Spain, [Cabrera-Leon, Andres] Andalusian Sch Publ Hlth, Granada 18080, Spain, [Cabrera-Leon, Andres] Network Biomed Res Ctr Epidemiol & Publ Hlth CIBE, Madrid 28029, Spain, Ministerio de Ciencia e Innovacion, Spain, and FPU grant from the Spanish Ministry of Science, Innovation and Universities
Subjects: Gerontology, propensity score adjustment, 020205 medical informatics, General Mathematics, media_common.quotation_subject, Population, education, 02 engineering and technology, Burnout, Ordinal regression, multivariate ordinal regression models, 03 medical and health sciences, online survey, self-perceived health, 0302 clinical medicine, Models, Health care, 0202 electrical engineering, electronic engineering, information engineering, Computer Science (miscellaneous), Medicine, 030212 general & internal medicine, Engineering (miscellaneous), media_common, Selection bias, education.field_of_study, business.industry, lcsh:Mathematics, Life satisfaction, lcsh:QA1-939, Physician, Calibration, Propensity score matching, Anxiety, medicine.symptom, business
Abstract: Healthcare professionals (HCPs) often suffer high levels of depression, stress, anxiety and burnout. Our main study aimswereto estimate the prevalences of poor self-perceived health, life dissatisfaction, chronic disease and unhealthy habits among HCPs and to explore the use of machine learning classification algorithms to remove selection bias. A sample of Spanish HCPs was asked to complete a web survey. Risk factors were identified by multivariate ordinal regression models. To counteract the absence of probabilistic sampling and representation, the sample was weighted by propensity score adjustment algorithms. The logistic regression algorithm was considered the most appropriate for dealing with misestimations. Male HCPs had significantly worse lifestyle habits than their female counterparts, together with a higher prevalence of chronic disease and of health problems. Members of the general population reported significantly poorer health and less satisfaction with life than the HCPs. Among HCPs, the prior existence of health problems was most strongly associated with worsening self-perceived health and decreased life satisfaction, while obesity had an important negative impact on female practitioners’ self-perception of health. Finally, the HCPs who worked as nurses had poorer self-perceptions of health than other HCPs, and the men who worked in primary care had less satisfaction with their lives than those who worked in other levels of healthcare., Ministerio de Ciencia e Innovación, Spain
Published: 2021

7. Player Selection for a National Football Team using Fuzzy AHP and Fuzzy TOPSIS

Author: Nimet Yapıcı Pehlivan, Unal, Yener, Kahraman, Cengiz, and [Pehlivan, Nimet Yapici] Selcuk Univ, Dept Stat, Campus Konya, TR-42075 Konya, Turkey -- [Unal, Yener] Cumhuriyet Univ, Dept Stat, TR-58140 Sivas, Turkey -- [Kahraman, Cengiz] Istanbul Tech Univ, Dept Ind Engn, TR-34367 Macka Istanbul, Turkey
Subjects: Fuzzy multi criteria decision making, player selection, fuzzy AHP, turkish national football team, fuzzy TOPSIS
Abstract: WOS: 000466982400001, Player selection is an important process which takes technical, personal and ability attributes of players into account. Determination of optimal team for Turkish A National Football Team is quite important for Turkey's ranking in the world among the other teams. When the decision makers' judgements are under uncertainty, it is relatively difficult for them to make a decision. The fuzzy set theory is a strong tool which can deal with the uncertainty in case of subjective, incomplete and vague information. Under this kind of uncertainty, it might be appropriate for decision makers to make an evaluation by linguistic terms. The aim of the paper is to select the best players for the team by taking several criteria into account. Fuzzy AHP, Fuzzy TOPSIS and Integrated FAHP/FTOPSIS methods are comparatively applied to the selection process of players for forming an optimal squad of Turkish National Football Team.
Published: 2019

8. Calibrated prevalence of disabling chronic pain according to different approaches: a face-to-face cross-sectional population-based study in Southern Spain

Author: Miguel Ángel Cantero-Braojos, Andrés Cabrera-León, María del Mar Rueda, [Cabrera-Leon, Andres] Univ Granada, Hosp Univ Granada, Andalusian Sch Publ Hlth, Inst Invest Biosanitariaibs GRANADA, Granada, Spain, [Cabrera-Leon, Andres] Biomed Res Networking Ctr Publ Hlth & Epidemiol C, Madrid, Spain, [Cabrera-Leon, Andres] Univ Granada, Math Inst IEMath GR, Dept Stat & OR, Granada, Spain, [Rueda, Maria] Univ Granada, Math Inst IEMath GR, Dept Stat & OR, Granada, Spain, [Cantero-Braojos, Miguel] Psychol & Hlth Mensana, Psychol & Clin Physiotherapist, Granada, Spain, Ministry of Health of the Andalusian Government, Seville, Spain, Ministerio de Educacion, Cultura y Deporte (Spain), Allergan Inc., [Cabrera-León,A] Andalusian School of Public Health, Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain. [Cabrera-León,A] Biomedical Research Networking Centre on Public Health and Epidemiology (CIBERESP), Madrid, Spain. [Cabrera-León,A] Department of Statistics and O.R, Math Institute (IEMath-GR), University of Granada, Granada, Spain. [Rueda,M] Department of Statistics and O.R, Math Institute (IEMath-GR), University of Granada, Granada, Spain. [Cantero-Braojos,M] Psychologist and Clinical Physiotherapist, Psychology and Health Mensana, Granada, Spain, and This study was partially supported by Ministerio de Educación, Cultura y Deporte (grant number MTM2015-63609-R, Spain) and by Allergan Inc.
Subjects: Calibración, Estudios transversales, Calibration (statistics), Cross-sectional study, Epidemiology, España, Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings], cross-sectional studies, Chronic pain, Community, Auxiliary information, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Calibration [Medical Subject Headings], Face-to-face, Disability Evaluation, Diseases::Nervous System Diseases::Neurologic Manifestations::Pain::Chronic Pain [Medical Subject Headings], 0302 clinical medicine, Prevalence, 030212 general & internal medicine, education.field_of_study, Age Factors, General Medicine, Middle Aged, Impact, Calibration, Educational Status, Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence [Medical Subject Headings], Adult, Adolescent, Population, Sample (statistics), 03 medical and health sciences, Young Adult, Sex Factors, Age groups, medicine, Adults, Humans, education, Aged, Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings], Disability, Questionnaire, business.industry, Research, Dolor crónico, medicine.disease, Health Surveys, Population based study, Small areas, Logistic Models, disability, Spain, Prevalencia, business, indirect estimation techniques, 030217 neurology & neurosurgery, Demography
Abstract: Objectives To calculate the prevalence of disabling chronic pain (DCP) and to offer a more representative and accurate estimation by applying different calibration techniques. Settings 2011 Andalusian Health Survey, a cross-sectional population survey based on face-to-face home interviews. Participants 6507 people aged 16 years or older and living in Andalusia, Spain. Outcomes Design weights, linear calibration based on marginals and on crossings, and model-assisted calibration were used to estimate the prevalence and variance of DCP, for the whole sample and for the domains of sex and age groups (16–44; 45–64; +65). Results Calibration variables were sex, age groups and educational level. In the whole sample, DCP prevalence calibration reduced by more than 5.2% and 8.2% the estimated prevalences and variances, respectively, obtained with the design weights. Regarding the domains, prevalence reductions are from 33% to 1%, and variance reductions are from 0.2% to 1%. Model-assisted calibration is the best technique to estimate DCP prevalence for the whole population and crossing calibration for their domains, although with almost no differences compared to marginal calibration. Conclusions The validity and accuracy of estimations of DCP prevalence are improved by calibration adjustments. Model-assisted calibrated prevalence of DCP is 10.78% for the whole population, being at least 2-fold higher in women in all age groups. The results and methodology developed could be useful in clinical and population-based studies on chronic pain and disability., Ministerio de Educación, Cultura y Deporte, Ministry of Health of the Andalusian Government, Seville, Spain, Allergan Inc.
Published: 2017

9. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Author: Tazeen H. Jafar, Lars Lind, Peter Almgren, Wendy Winckler, Eitaro Nakashima, Young Min Cho, Annette Peters, Rona J. Strawbridge, Ananda R. Wickremasinghe, Katharine R. Owen, Lee-Ming Chuang, Tien-Jyun Chang, Graeme I. Bell, James B. Meigs, Bill Musk, Timo A. Lakka, Elin Grundberg, Wei Lu, Sarah Edkins, George Dedoussis, Weiping Jia, Danish Saleheen, Suthesh Sivapalaratnam, Maria Samuel, Tien Yin Wong, Lu Qi, Pierre Fontanillas, Momoko Horikoshi, Jirong Long, Abdul Basit, Anubha Mahajan, Andrew T. Hattersley, Markus M. Nöthen, Denis Rybin, Inger Njølstad, S. Krithika, Miguel Cruz, Delilah Zabaneh, Leena Peltonen, Jasmina Kravic, Sangsoo Kim, David Couper, Lori L. Bonnycastle, Heather M. Stringham, Yi-Cheng Chang, Paul Elliott, Eric J.G. Sijbrands, Nita G. Forouhi, Alena Stančáková, Ghazala Mirza, Robert W. Lawrence, Ruth J. F. Loos, Norman Klopp, Shiro Maeda, Martina Müller-Nurasyid, Jer-Yuarn Wu, Jianjun Liu, Kee Seng Chia, Elodie Eury, Loukianos S. Rallidis, Timothy M. Frayling, Ken Yamamoto, David Altshuler, Gunnar Sigurosson, Harald Grallert, Jackie F. Price, Barbara Thorand, Jouko Saramies, Malene M. Kristensen, Sonali Pechlivanis, Inês Barroso, Jong-Young Lee, Melissa Parkin, Josée Dupuis, Stéphane Lobbens, Jesús Kumate, Elena Tremoli, Sudhir Kowlessur, Xueling Sim, Norihiro Kato, Philippe Froguel, Kathleen Stirrups, Eero Lindholm, Alex S. F. Doney, Andres Metspalu, Yu-Tang Gao, Roman Wennauer, Xiao-Ou Shu, Marilyn C. Cornelis, Veikko Salomaa, Nanette R. Lee, Johanna Kuusisto, Caroline S. Fox, Man Li, James Scott, Wing-Yee So, Andrew R. Wood, Inga Prokopenko, Oddgeir L. Holmen, Tin Aung, Ryoichi Takayanagi, Chen Suo, Hara Kazuo, Carl G. P. Platou, Ann M. Kelly, Teresa Ferreira, Karl-Heinz Jöckel, Wei-Yen Lim, James F. Wilson, Tom Forsén, Qi Sun, Valur Emilsson, Gonçalo R. Abecasis, Fan Zhang, Timo Saaristo, Harry Campbell, Ying Wu, Mark Seielstad, Wei Zheng, Han Chen, Stavroula Kanoni, Yuqian Bao, Jose C. Florez, Wan Ting Tay, Ronald C. WMa, Gerald Steinbach, Min Jin Go, Rong Zhang, Junbin Liang, Vasiliki Lagou, Leif Groop, Emil Rehnberg, Nabi Shah, Weihua Zhang, Yun Li, Bengt Sennblad, Olle Melander, Nancy L. Pedersen, Muhammed Islam, Jaakko Tuomilehto, Young Jin Kim, Richard N. Bergman, Juliana C.N. Chan, Eleftheria Zeggini, Andrew D. Johnson, Kees Hovingh, Joban Sehmi, Rainer Rauramaa, Satu Männistö, Reedik Mägi, Samuel Liju, Mingyu Yang, Ayellet V. Segrè, Noël P. Burtt, Mozhgan Dorkhan, Beverley Balkau, Neelam Hassanali, Hyun Min Kang, Fabrizio Veglia, Eeva Korpi-Hyövälti, Loic Yengo, Elizabeth J. Rossin, Angela Silveira, Maggie C.Y. Ng, Yuan-Tsong Chen, Anders Hamsten, David R. Matthews, Mark J. Caulfield, Emmi Tikkanen, Tanya M. Teslovich, John R. B. Perry, Karen L. Mohlke, Sarah E. Hunt, Soo Heon Kwak, Jorge Escobedo, Christopher J. Groves, Ulf de Faire, Jeremy B M Jowett, Gudmar Thorleifsson, Michael Roden, Evelin Mihailov, Viswanathan Mohan, Craig L. Hanis, Thomas WMühleisen, Congrong Wang, Sonia Shah, Kyle J. Gaulton, Jaspal S. Kooner, Jiro Nakamura, Mustafa Atalay, Linda S. Adair, S Wiltshire, Tõnu Esko, Anna Jonsson, Antigone S. Dimas, Karin Leander, Li Ching Chang, George B. Grant, Bo Isomaa, Anne U. Jackson, Claudia Langenberg, Kristian Hveem, Yoon Shin Cho, Astradur B. Hreidarsson, Xu Wang, Keizo Ohnaka, Alexandra C. Nica, Simon D. Rees, Pau Navarro, Sekar Kathiresan, Rob M. van Dam, Zafar I. Hydrie, Bok Ghee Han, Francis S. Collins, Fuu Jen Tsai, Unnur Thorsteinsdottir, Ross M. Fraser, Caroline Hayward, Cornelia M. van Duijn, Samuli Ripatti, Mieke D. Trip, Hyung Lae Kim, Rafn Benediktsson, Candace Guiducci, Bruna Gigante, Kyong Soo Park, Wen Hong L. Kao, Tom Wilsgaard, Leena Kinnunen, John Danesh, Alan James, Alan R. Shuldiner, Mitsuhiro Yokota, Jen Mai Lee, Kari Stefansson, Erik Ingelsson, Colin N. A. Palmer, David J. Hunter, Paul Zimmet, Manickam Chidambaram, Sirkka Keinänen-Kiukaanniemi, Laura J. Scott, Susanne Moebus, Benjamin F. Voight, Wolfgang Rathmann, Hassan Khan, Thomas Illig, Prasad Katulanda, Christian Gieger, Andrew D. Morris, Yik Ying Teo, Andrew P. Morris, Venkatesan Radha, N. William Rayner, Johan G. Eriksson, Christian Dina, Igor Rudan, Sailaja Vedantam, Cheng Hu, James S. Pankow, Ann-Christine Syvänen, Karl Gertow, Valeriya Lyssenko, Guillaume Charpentier, Albert Hofman, Chiea Chuen Khor, Joseph Trakalo, Peter Kraft, Takashi Kadowaki, Qiuyin Cai, John C. Chambers, André G. Uitterlinden, Simon C. Potter, Nicholas J. Wareham, Soumya Raychaudhuri, Jian'an Luan, Tiinamaija Tuomi, Anthony H. Barnett, Juha Saltevo, Robert A. Scott, Valgerdur Steinthorsdottir, Peng Keat Ng, Mark I. McCarthy, Åsa K. Hedman, Kerrin S. Small, Julia Meyer, Frank B. Hu, Cecilia M. Lindgren, Jennifer E. Below, Nancy J. Cox, Jennie Hui, Andrew Crenshaw, Latonya F. Been, Nam H. Cho, Janani Pinidiyapathirage, A. Samad Shera, Bernhard OBoehm, Jason Carey, Augustine Kong, Twee Hee Ong, Philippe M. Frossard, Donald W. Bowden, Toshimasa Yamauchi, Steve E. Humphries, Cordelia Langford, Xinzhong Li, Hiroshi Ikegami, Stéphane Cauchi, Ching-Ti Liu, Michael Boehnke, Peter M. Nilsson, Debashish Das, John Beilby, Robin Young, Christian Herder, Asif Rasheed, Neil Robertson, Raimund Erbel, Fumihiko Takeuchi, Markku Laakso, Esteban J. Parra, Panos Deloukas, Eric Boerwinkle, Adan Valladares-Salgado, Chien-Hsiun Chen, Kay-Tee Khaw, Damiano Baldassarre, Ashok Kumar, E. Shyong Tai, Peter S. Chines, Dharambir KSanghera, Peter Donnelly, [ 1 ] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England [ 2 ] Natl Inst Hlth, Ctr Genome Sci, Gangoe Myeon, Yeonje Ri, South Korea [ 3 ] Univ London Imperial Coll Sci Technol & Med, London, England [ 4 ] Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA [ 5 ] Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford OX1 2JD, England [ 6 ] NHLBI, Framingham Heart Study, Framingham, MA USA [ 7 ] Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC USA [ 8 ] Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC USA [ 9 ] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, London, England [ 10 ] Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England [ 11 ] Ctr Noncommunicable Dis Pakistan, Karachi, Pakistan [ 12 ] Natl Univ Singapore, Dept Epidemiol & Publ Hlth, Singapore 117548, Singapore [ 13 ] Wellcome Trust Sanger Inst, Cambridge, England [ 14 ] Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA [ 15 ] Univ N Carolina, Dept Nutr, Chapel Hill, NC USA [ 16 ] Lund Univ, Scania Univ Hosp, Dept Clin Sci Malmo, Ctr Diabet, Malmo, Sweden [ 17 ] Univ Eastern Finland, Inst Biomed, Kuopio, Finland [ 18 ] Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore [ 19 ] Natl Univ Singapore, Dept Ophthalmol, Singapore 117548, Singapore [ 20 ] IRCCS, Ctr Cardiol Monzino, Milan, Italy [ 21 ] Univ Milan, Dept Pharmacol Sci, Milan, Italy [ 22 ] INSERM, Ctr Rech Epidemiol & Sante Populat CESP, U1018, Villejuif, France [ 23 ] Univ Paris 11, UMRS 1018, Villejuif, France [ 24 ] Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Endocrinol & Metab, Shanghai Key Lab Diabet Mellitus,Shanghai Diabet, Shanghai 200030, Peoples R China [ 25 ] Univ Birmingham, Coll Med & Dent Sci, Birmingham, W Midlands, England [ 26 ] Heart England Natl Hlth Serv NHS Fdn Trust, Ctr Biomed Res, Birmingham, W Midlands, England [ 27 ] Univ Cambridge, Addenbrookes Hosp, Metab Res Labs, Inst Metab Sci, Cambridge CB2 2QQ, England [ 28 ] Addenbrookes Hosp, Inst Metab Sci, Cambridge Biomed Res Ctr, Natl Inst Hlth Res, Cambridge, England [ 29 ] Baqai Inst Diabetol & Endocrinol, Karachi, Pakistan [ 30 ] Univ Oklahoma, Hlth Sci Ctr, Coll Med, Dept Pediat,Sect Genet, Oklahoma City, OK 73190 USA [ 31 ] Sir Charles Gairdner Hosp, Busselton Populat Med Res Inst, Nedlands, WA 6009, Australia [ 32 ] Queen Elizabeth II Med Ctr, PathWest Lab Med Western Australia, Nedlands, WA, Australia [ 33 ] Univ Western Australia, Sch Pathol & Lab Med, Nedlands, WA 6009, Australia [ 34 ] Univ Chicago, Dept Med, Chicago, IL 60637 USA [ 35 ] Univ Chicago, Dept Human Genet, Chicago, IL 60637 USA [ 36 ] Univ Iceland, Fac Med, Reykjavik, Iceland [ 37 ] Landspitali Univ Hosp, Reykjavik, Iceland [ 38 ] Cedars Sinai Med Ctr, Diabet & Obes Res Inst, Los Angeles, CA 90048 USA [ 39 ] Univ Med Ctr Ulm, Div Endocrinol & Diabet, Dept Internal Med, Ulm, Germany [ 40 ] Nanyang Technol Univ, Lee Kong Chian LKC Sch Med, Singapore 639798, Singapore [ 41 ] Univ Texas Hlth Sci Ctr Houston, Ctr Human Genet, Houston, TX 77030 USA [ 42 ] Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA [ 43 ] NHGRI, NIH, Bethesda, MD 20892 USA [ 44 ] Broad Inst Harvard & Massachusetts Inst Technol M, Cambridge, MA USA [ 45 ] Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37212 USA [ 46 ] Univ Edinburgh, Ctr Populat Hlth Sci, Edinburgh, Midlothian, Scotland [ 47 ] Univ Edinburgh, Western Gen Hosp, MRC, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland [ 48 ] CNRS, Unite Mixte Rech UMR 8199, Inst Biol, Lille, France [ 49 ] Univ Lille 2, Inst Pasteur, Lille, France [ 50 ] Queen Mary Univ London, Barts & London Sch Med, William Harvey Res Inst, London, England [ 51 ] Queen Mary Univ London, Barts & London Sch Med, William Harvey Res Inst, Barts & London Genome Ctr, London, England [ 52 ] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China [ 53 ] Acad Sinica, Inst Biomed Sci, Taipei, Taiwan [ 54 ] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei 100, Taiwan [ 55 ] Corbeil Essonnes Hosp, Endocrinol Diabetol Unit, Corbeil Essonnes, France [ 56 ] China Med Univ, Sch Chinese Med, Taichung, Taiwan [ 57 ] Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA [ 58 ] Natl Univ Singapore, Ctr Mol Epidemiol, Singapore 117548, Singapore [ 59 ] Indian Council Med Res, Adv Ctr Genom Diabet, Madras Diabet Res Fdn, Dept Mol Genet, Madras, Tamil Nadu, India [ 60 ] Ajou Univ, Sch Med, Dept Prevent Med, Suwon 441749, South Korea [ 61 ] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 151, South Korea [ 62 ] Natl Taiwan Univ, Sch Med, Grad Inst Clin Med, Taipei 10764, Taiwan [ 63 ] Harvard Univ, Sch Publ Hlth, Dept Nutr & Epidemiol, Boston, MA 02115 USA [ 64 ] Univ N Carolina, Dept Biostat, Collaborat Studies Coordinating Ctr, Chapel Hill, NC USA [ 65 ] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117548, Singapore [ 66 ] Ealing Hosp NHS Trust, Southall, Middx, England [ 67 ] Karolinska Inst, Inst Environm Med, Divis Cardiovasc Epidemiol, S-10401 Stockholm, Sweden [ 68 ] Harokopio Univ, Dept Dietet Nutr, Athens, Greece [ 69 ] Univ Geneva, Sch Med, Dept Genet Med & Dev, CH-1211 Geneva, Switzerland [ 70 ] Biomed Sci Res Ctr Alexander Fleming, Vari, Greece [ 71 ] INSERM, UMR 1087, Nantes, France [ 72 ] CNRS, UMR 6291, Nantes, France [ 73 ] Univ Nantes, Nantes, France [ 74 ] Univ Dundee, Ninewells Hosp, Biomed Res Inst, Diabet Res Ctr, Dundee, Scotland [ 75 ] Univ Dundee, Ninewells Hosp, Biomed Res Inst, Pharmacogen Ctr, Dundee, Scotland [ 76 ] Univ Oxford, Dept Stat, Oxford OX1 3TG, England [ 77 ] Erasmus Univ, Med Ctr, Dept Epidemiol, Rotterdam, Netherlands [ 78 ] Netherlands Consortium Healthy Ageing, Netherland Genom Initiat, Rotterdam, Netherlands [ 79 ] Ctr Med Syst Biol, Rotterdam, Netherlands [ 80 ] Univ London Imperial Coll Sci Technol & Med, MRC, Hlth Protect Agcy, Ctr Environm & Hlth, London, England [ 81 ] Iceland Heart Assoc, Kopavogur, Iceland [ 82 ] Univ Duisburg Essen, Univ Hosp Essen, West German Heart Ctr, Clin Cardiol, Essen, Germany [ 83 ] Natl Inst Hlth & Welf, Dept Chron Dis Prevent, Helsinki, Finland [ 84 ] Univ Helsinki, Dept Gen Practice & Primary Hlth Care, Helsinki, Finland [ 85 ] Univ Helsinki, Gen Hosp, Unit Gen Practice, Helsinki, Finland [ 86 ] Folkhalsan Res Ctr, Helsinki, Finland [ 87 ] Inst Mexicano Seguro Social, Hosp Gen Reg 1, Unidad Invest Epidemiol Clin, Mexico City, DF, Mexico [ 88 ] Univ Tartu, Estonian Genome Ctr, EE-50090 Tartu, Estonia [ 89 ] Univ Tartu, Inst Mol & Cell Biol, EE-50090 Tartu, Estonia [ 90 ] Broad Inst, Program Med & Populat Genet, Cambridge, MA USA [ 91 ] Childrens Hosp, Div Genet & Endocrinol, Boston, MA 02115 USA [ 92 ] Harvard Univ, Sch Med, Dept Med, Boston, MA USA [ 93 ] Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA [ 94 ] Massachusetts Gen Hosp, Diabet Res Ctr, Diabet Unit, Boston, MA 02114 USA [ 95 ] Addenbrookes Hosp, Inst Metab Sci, MRC, Epidemiol Unit, Cambridge, England [ 96 ] Vaasa Hlth Care Ctr, Vaasa, Finland [ 97 ] Brigham & Womens Hosp, Div Endocrinol & Metab, Boston, MA 02115 USA [ 98 ] Harvard Univ, Sch Med, Boston, MA USA [ 99 ] Univ Exeter, Peninsula Med Sch, Inst Biomed & Clin Sci, Exeter, Devon, England [ 100 ] Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China [ 101 ] Karolinska Inst, Dept Med Solna, Atherosclerosis Res Unit, Stockholm, Sweden [ 102 ] Karolinska Univ, Hosp Solna, Ctr Mol Med, Stockholm, Sweden [ 103 ] Helmholtz Zentrum Muenchen, Inst Genet Epidemiol, Neuherberg, Germany [ 104 ] Helmholtz Zentrum Muenchen, Res Unit Mol Epidemiol, Neuherberg, Germany [ 105 ] Univ Munich, Clin Cooperat Grp Diabet, Munich, Germany [ 106 ] Helmholtz Zentrum Muenchen, Munich, Germany [ 107 ] Tech Univ Munich, Clin Cooperat Grp Nutrigen & Type Diabet 2, Munich, Germany [ 108 ] German Ctr Diabet Res DZD, Neuherberg, Germany [ 109 ] Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England [ 110 ] Univ Tokyo, Grad Sch Med, Dept Diabet & Metab Dis, Tokyo, Japan [ 111 ] Univ Exeter, Peninsula Med Sch, Inst Biomed & Clin Sci, Exeter, Devon, England [ 112 ] Univ Dusseldorf, Leibniz Ctr Diabet Res, German Diabet Ctr, Inst Clin Diabetol, Dusseldorf, Germany [ 113 ] Norwegian Univ Sci & Technol, Dept Publ Hlth & Gen Practice, HUNT Res Ctr, Levanger, Norway [ 114 ] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands [ 115 ] Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA USA [ 116 ] Univ Western Australia, Sch Populat Hlth, Nedlands, WA 6009, Australia [ 117 ] UCL, Inst Cardiovasc Sci, London, England [ 118 ] Harvard Univ, Sch Publ Hlth, Program Mol & Genet Epidemiol, Boston, MA 02115 USA [ 119 ] Kinki Univ, Sch Med, Dept Diabet Endocrinol & Metab, Osaka 589, Japan [ 120 ] Hannover Med Sch, Hannover Unified Biobank, Hannover, Germany [ 121 ] Univ Uppsala Hosp, Dept Mol Sci, Mol Epidemiol & Sci Life Lab, Uppsala, Sweden [ 122 ] Aga Khan Univ, Dept Community Hlth Sci, Karachi, Pakistan [ 123 ] Dept Social Serv & Hlth Care, Pietarsaari, Finland [ 124 ] Aga Khan Univ, Dept Med, Karachi, Pakistan [ 125 ] Queen Elizabeth II Med Ctr, West Australian Sleep Disorders Res Inst, Dept Pulm Physiol & Sleep Med, Nedlands, WA, Australia [ 126 ] Univ Western Australia, Sch Med & Pharmacol, Nedlands, WA 6009, Australia [ 127 ] Univ Hosp Essen, Inst Med Informat Biometry & Epidemiol, Essen, Germany [ 128 ] Heart & Diabet Inst, Baker Int Diabet Inst IDI, Melbourne, Australia [ 129 ] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA [ 130 ] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA [ 131 ] Natl Ctr Global Hlth & Med, Res Inst, Shinjuku Ku, Tokyo, Japan [ 132 ] Univ Colombo, Dept Clin Med, Diabet Res Unit, Colombo, Sri Lanka [ 133 ] Univ Oulu, Inst Hlth Sci, Fac Med, Oulu, Finland [ 134 ] Oulu Univ Hosp, Unit Gen Practice, Oulu, Finland [ 135 ] Agcy Sci Technol & Res, Genome Inst Singapore, Singapore, Singapore [ 136 ] Ewha Womans Univ, Sch Med, Dept Biochem, Seoul, South Korea [ 137 ] Soongsil Univ, Sch Syst Biomed Sci, Seoul, South Korea [ 138 ] Natl Inst Hlth & Welf, Diabet Prevent Unit, Helsinki, Finland [ 139 ] deCODE Genet, Reykjavik, Iceland [ 140 ] South Ostrobothnia Cent Hosp, Seinajoki, Finland [ 141 ] Minist Hlth, Port Louis, Mauritius [ 142 ] Univ Toronto, Dept Anthropol, Mississauga, ON L5L 1C6, Canada [ 143 ] Fdn IMSS, Mexico City, DF, Mexico [ 144 ] Univ Eastern Finland, Dept Med, Kuopio, Finland [ 145 ] Kuopio Univ Hosp, SF-70210 Kuopio, Finland [ 146 ] Kuopio Res Inst Exercise Med, Kuopio, Finland [ 147 ] Univ Western Australia, Ctr Genet Epidemiol & Biostat, Nedlands, WA 6009, Australia [ 148 ] Univ San Carlos, Off Populat Studies Fdn Inc, Cebu, Philippines [ 149 ] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Natl Heart & Lung Inst, London, England [ 150 ] Univ N Carolina, Dept Genet, Chapel Hill, NC USA [ 151 ] Univ N Carolina, Dept Biostat, Chapel Hill, NC USA [ 152 ] Beijing Genom Inst, Shenzhen, Peoples R China [ 153 ] Uppsala Univ, Akad Sjukhuset, Dept Med Sci, Uppsala, Sweden [ 154 ] Mt Sinai Sch Med, Charles R Bronfman Inst Personalized Med, New York, NY USA [ 155 ] Mt Sinai Sch Med, Child Hlth & Dev Inst, New York, NY USA [ 156 ] Mt Sinai Sch Med, Dept Prevent Med, New York, NY USA [ 157 ] Shanghai Inst Prevent Med, Shanghai, Peoples R China [ 158 ] Massachusetts Gen Hosp, Div Gen Med, Boston, MA 02114 USA [ 159 ] Dr Mohans Diabet Specialties Ctr, Madras, Tamil Nadu, India [ 160 ] Univ Bonn, Inst Human Genet, Bonn, Germany [ 161 ] Univ Bonn, Life & Brain Ctr, Dept Genom, Bonn, Germany [ 162 ] Univ Munich, Chair Genet Epidemiol, Inst Med Informat Biometry & Epidemiol, Munich, Germany [ 163 ] Univ Munich, Univ Hosp Grosshadern, Dept Med 1, Munich, Germany [ 164 ] Sir Charles Gairdner Hosp, Nedlands, WA 6009, Australia [ 165 ] Nagoya Univ, Grad Sch Med, Div Endocrinol & Diabet, Dept Internal Med, Nagoya, Aichi 4648601, Japan [ 166 ] Chubu Rosai Hosp, Dept Endocrinol & Diabet, Nagoya, Aichi, Japan [ 167 ] Univ Tromso, Fac Hlth Sci, Dept Community Med, Tromso, Norway [ 168 ] Kyushu Univ, Grad Sch Med Sci, Dept Geriatr Med, Higashi Ku, Fukuoka 812, Japan [ 169 ] Churchill Hosp, Hlth Res Biomed Res Ctr, Oxford Natl Inst, Oxford OX3 7LJ, England [ 170 ] Univ Minnesota, Div Epidemiol & Community Hlth, Minneapolis, MN USA [ 171 ] Seoul Natl Univ, Grad Sch Convergence Sci & Technol, Dept Mol Med & Biopharmaceut Sci, World Class Univ Program, Seoul, South Korea [ 172 ] Seoul Natl Univ, Coll Med, Seoul, South Korea [ 173 ] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden [ 174 ] Inst Mol Med Finland FIMM, Helsinki, Finland [ 175 ] Helmholtz Zentrum Muenchen, Inst Epidemiol 2, Neuherberg, Germany [ 176 ] Univ Kelaniya, Fac Med, Dept Publ Hlth, Ragama, Sri Lanka [ 177 ] Nord Trondelag Hlth Trust, Levanger Hosp, Dept Internal Med, Levanger, Norway [ 178 ] Univ Gen Hosp Attikon, Athens, Greece [ 179 ] Univ Dusseldorf, Leibniz Ctr Diabet Res, German Diabet Ctr, Inst Biometr & Epidemiol, Dusseldorf, Germany [ 180 ] Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, SF-70210 Kuopio, Finland [ 181 ] Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Rheumatol Immunol & Allergy, Boston, MA 02115 USA [ 182 ] Partners Ctr Personalized Genom Med, Boston, MA USA [ 183 ] Univ Dusseldorf, Dept Endocrinol & Diabetol, Dusseldorf, Germany [ 184 ] Univ Dusseldorf, Dept Metab Dis, Dusseldorf, Germany [ 185 ] Harvard Univ, Hlth Sci & Technol MD Program, Boston, MA 02115 USA [ 186 ] MIT, Boston, MA USA [ 187 ] Harvard Univ, Harvard Biol & Biomed Sci Program, Boston, MA 02115 USA [ 188 ] Boston Univ, Data Coordinating Ctr, Boston, MA 02215 USA [ 189 ] Finnish Diabet Assoc, Tampere, Finland [ 190 ] Pirkanmaa Hosp Dist, Tampere, Finland [ 191 ] Cent Finland Cent Hosp, Dept Med, Jyvaskyla, Finland [ 192 ] South Karelia Cent Hosp, Lappeenranta, Finland [ 193 ] UCL, Dept Genet Evolut & Environm, Genet Inst, London, England [ 194 ] Diabet Assoc Pakistan, Karachi, Pakistan [ 195 ] Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Baltimore, MD 21201 USA [ 196 ] Baltimore Vet Adm Med Ctr, Geriatr Res Educ & Clin Ctr, Baltimore, MD USA [ 197 ] Univ Maryland, Sch Med, Program Personalised & Genom Med, Baltimore, MD 21201 USA [ 198 ] Erasmus Univ, Med Ctr, Dept Internal Med, Rotterdam, Netherlands [ 199 ] Univ Ulm, Dept Clin Chem, D-89069 Ulm, Germany [ 200 ] Univ Ulm, Cent Lab, D-89069 Ulm, Germany [ 201 ] Uppsala Univ, Dept Med Sci, Uppsala, Sweden [ 202 ] Kyushu Univ, Grad Sch Med Sci, Dept Internal Med & Bioregulatory Sci, Higashi Ku, Fukuoka 812, Japan [ 203 ] Univ Helsinki, Helsinki Univ Hosp, Dept Med, Helsinki, Finland [ 204 ] Hosp Univ LaPaz IdiPAZ, Inst Invest Sanitaria, Madrid, Spain [ 205 ] Danube Univ Krems, Ctr Vasc Prevent, Krems, Austria [ 206 ] King Abdulaziz Univ, Diabet Res Grp, Jeddah 21413, Saudi Arabia [ 207 ] IMSS, Ctr Med Nacl Siglo 21, Hosp Especialidades, Unidad Invest Med Bioquim, Mexico City, DF, Mexico [ 208 ] Univ Penn, Perelman Sch Med, Dept Pharmacol, Philadelphia, PA 19104 USA [ 209 ] Univ Melbourne, Ctr Eye Res Australia, East Melbourne, Vic, Australia [ 210 ] Kyushu Univ, Med Inst Bioregulat, Res Ctr Genet Informat, Div Genome Anal,Higashi Ku, Fukuoka 812, Japan [ 211 ] Univ Lille 1, Math Lab, CNRS UMR 8524, MODAL Team,INRIA Lille Nord Europe, F-59655 Villeneuve Dascq, France [ 212 ] Aichi Gakuin Univ, Sch Dent, Dept Genome Sci, Nagoya, Aichi 464, Japan [ 213 ] Harvard Univ, Sch Med, Dept Genet, Boston, MA USA [ 214 ] Harvard Univ, Sch Med, Dept Mol Biol, Boston, MA USA [ 215 ] Massachusetts Gen Hosp, Diabet Unit, Boston, MA 02114 USA [ 216 ] Wake Forest Sch Med, Dept Biochem, Winston Salem, NC USA [ 217 ] Wake Forest Sch Med, Dept Internal Med, Winston Salem, NC USA [ 218 ] Hallym Univ, Dept Biomed Sci, Chunchon, Gangwon Do, South Korea [ 219 ] Univ Texas Hlth Sci Ctr Houston, Ctr Human Genet, Houston, TX 77030 USA [ 220 ] Imperial Coll Healthcare NHS Trust, London, England [ 221 ] Univ Calif San Francisco, Inst Human Genet, San Francisco, CA 94143 USA [ 222 ] Blood Syst Res Inst, San Francisco, CA USA [ 223 ] Natl Univ Singapore, Grad Sch Integrat Sci & Engn, Singapore 117548, Singapore [ 224 ] Natl Univ Singapore, Dept Stat & Appl Probabil, Singapore 117548, Singapore [ 225 ] Natl Univ Singapore, Dept Med, Singapore 117548, Singapore [ 226 ] Duke Natl Univ Singapore, Grad Sch Med, Singapore, Singapore [ 227 ] Univ Liverpool, Dept Biostat, Liverpool L69 3BX, Merseyside, England, Obstetrics & Gynecology, Radiology & Nuclear Medicine, Surgery, Epidemiology, Dermatology, Internal Medicine, Medical Microbiology & Infectious Diseases, Medical Research Council (MRC), National Institute for Health Research, ACS - Amsterdam Cardiovascular Sciences, Vascular Medicine, and Cardiology
Subjects: CHROMATIN, endocrine system diseases, South Asian Type 2 Diabetes (SAT2D) Consortium, SCALE ASSOCIATION ANALYSIS, Medizin, LOCI, Genome-wide association study, VARIANTS, 0302 clinical medicine, Risk Factors, IMPUTATION, Glucose homeostasis, 11 Medical and Health Sciences, Genetics & Heredity, Genetics, 0303 health sciences, IDENTIFY, Hispanic or Latino, 3. Good health, MAP, POPULATIONS, Medical genetics, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, Hispanic Americans, Life Sciences & Biomedicine, Asian Continental Ancestry Group, medicine.medical_specialty, European Continental Ancestry Group, TRANSETHNIC METAANALYSIS, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Article, White People, Sykursýki, 03 medical and health sciences, Asian People, SDG 3 - Good Health and Well-being, medicine, Humans, Genetic Predisposition to Disease, Allele, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, Alleles, 030304 developmental biology, Genetic association, Science & Technology, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, 06 Biological Sciences, Arfgengi, Genetic architecture, INDIVIDUALS, Diabetes Mellitus, Type 2, Case-Control Studies, GLUCOSE-HOMEOSTASIS, ASSOCIATION ANALYSES, Imputation (genetics), Developmental Biology, Genome-Wide Association Study
Abstract: To access publisher's full text version of this article click on the hyperlink at the bottom of the page To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry. We observed a significant excess in the directional consistency of T2D risk alleles across ancestry groups, even at SNPs demonstrating only weak evidence of association. By following up the strongest signals of association from the trans-ethnic meta-analysis in an additional 21,491 cases and 55,647 controls of European ancestry, we identified seven new T2D susceptibility loci. Furthermore, we observed considerable improvements in the fine-mapping resolution of common variant association signals at several T2D susceptibility loci. These observations highlight the benefits of trans-ethnic GWAS for the discovery and characterization of complex trait loci and emphasize an exciting opportunity to extend insight into the genetic architecture and pathogenesis of human diseases across populations of diverse ancestry. Canadian Institutes of Health Research Medical Research Council UK G0601261 Mexico Convocatoria SSA/IMMS/ISSSTE-CONACYT 2012-2 clave 150352 IMSS R-2011-785-018 CONACYT Salud-2007-C01-71068 US National Institutes of Health DK062370 HG000376 DK085584 DK085545 DK073541 DK085501 Wellcome Trust WT098017 WT090532 WT090367 WT098381 WT081682 WT085475 info:eu-repo/grantAgreement/EC/FP7/201413
Published: 2014
Full Text: View/download PDF

10. Multiplicative neuron model artificial neural network based on Gaussian activation function

Author: Erol Egrioglu, Ozge Gundogdu, Cagdas Hakan Aladag, Ufuk Yolcu, [Gundogdu, Ozge] Cumhuriyet Univ, Dept Econometr, Sivas, Turkey -- [Egrioglu, Erol] Marmara Univ, Dept Stat, Istanbul, Turkey -- [Aladag, Cagdas Hakan] Hacettepe Univ, Dept Stat, Ankara, Turkey -- [Yolcu, Ufuk] Ankara Univ, Dept Stat, TR-06100 Ankara, Turkey, and Egrioglu, Erol -- 0000-0003-4301-4149
Subjects: Artificial neural network, 0209 industrial biotechnology, Radial basis function network, Computer science, Gaussian, Computer Science::Neural and Evolutionary Computation, Activation function, 02 engineering and technology, symbols.namesake, 020901 industrial engineering & automation, Artificial Intelligence, 0202 electrical engineering, electronic engineering, information engineering, Stochastic neural network, Multiplicative neuron model, Quantitative Biology::Neurons and Cognition, business.industry, Particle swarm optimization, Rectifier (neural networks), Gaussian activation function, symbols, Feedforward neural network, 020201 artificial intelligence & image processing, Artificial intelligence, Types of artificial neural networks, business, Algorithm, Software, Forecasting
Abstract: WOS: 000374578800011, Multiplicative neuron model-based artificial neural networks are one of the artificial neural network types which have been proposed recently and have produced successful forecasting results. Sigmoid activation function was used in multiplicative neuron model-based artificial neural networks in the previous studies. Although artificial neural networks which involve the use of radial basis activation function produce more successful forecasting results, Gaussian activation function has not been used for multiplicative neuron model yet. In this study, rather than using a sigmoid activation function, Gaussian activation function was used in multiplicative neuron model artificial neural network. The weights of artificial neural network and parameters of activation functions were optimized by guaranteed convergence particle swarm optimization. Two major contributions of this study are as follows: the use of Gaussian activation function in multiplicative neuron model for the first time and the optimizing of central and propagation parameters of activation function with the weights of artificial neural network in a single optimization process. The superior forecasting performance of the proposed Gaussian activation function-based multiplicative neuron model artificial neural network was proved by applying it to real-life time series.
Published: 2016

11. Finding an optimal interval length in high order fuzzy time series

Author: Erol Egrioglu, Vedide Rezan Uslu, Ufuk Yolcu, Murat Basaran, Cagdas Hakan Aladag, Ondokuz Mayıs Üniversitesi, 0-Belirlenecek, Egrioglu, Erol -- 0000-0003-4301-4149, and [Aladag, Cagdas Hakan] Hacettepe Univ, Dept Stat, TR-06532 Ankara, Turkey -- [Egrioglu, Erol -- Yolcu, Ufuk -- Uslu, Vedide R.] Ondokuz Mayis Univ, Dept Stat, TR-55139 Samsun, Turkey -- [Basaran, Murat A.] Nigde Univ, Dept Math, TR-51000 Nigde, Turkey
Subjects: Optimization, Fuzzy sets, Mathematical optimization, High order fuzzy time series forecasting model, Series (mathematics), Fuzzy set, General Engineering, Univariate, Interval (mathematics), Fuzzy logic, Computer Science Applications, Order of integration, Length of interval, Artificial Intelligence, Golden section search, Successive parabolic interpolation, Forecasting, Mathematics
Abstract: WOS: 000277726300038, Univariate fuzzy time series approaches which have been widely used in recent years can be divided into two classes, which are called first order and high order models. In the literature, it has been shown that high order fuzzy time series approaches improve the forecasting accuracy. One of the important parts of obtaining high accuracy forecasts in fuzzy time series is that the length of interval is very vital. As mentioned in the first-order models by Egrioglu, Aladag, Basaran, Uslu, and Yolcu (2009), the length of interval also plays very important role in high order models too. In this study, a new approach which uses an optimization technique with a single-variable constraint is proposed to determine an optimal interval length in high order fuzzy time series models. An optimization procedure is used in order to determine optimum length of interval for the best forecasting accuracy, we used optimization procedure. In the optimization process, we used a MATLAB function employing an algorithm based on golden section search and parabolic interpolation. The proposed method was employed to forecast the enrollments of the University of Alabama to show the considerable outperforming results. (C) 2009 Elsevier Ltd. All rights reserved.
Published: 2010
Full Text: View/download PDF

12. Improving weighted information criterion by using optimization

Author: Murat Basaran, Cagdas Hakan Aladag, Erol Egrioglu, Süleyman Günay, 0-Belirlenecek, Ondokuz Mayıs Üniversitesi, Egrioglu, Erol -- 0000-0003-4301-4149, and [Aladag, Cagdas Hakan -- Gunay, Suleyman] Hacettepe Univ, Dept Stat, TR-06800 Ankara, Turkey -- [Egrioglu, Erol] Ondokuz Mayis Univ, Dept Stat, TR-55100 Samsun, Turkey -- [Basaran, Murat A.] Nigde Univ, Dept Math, TR-51000 Nigde, Turkey
Subjects: Mathematical optimization, Measure (data warehouse), Time series, Optimality criterion, Artificial neural network, Series (mathematics), Artificial neural networks, Model selection, Applied Mathematics, Computational Mathematics, Consistency (statistics), Weighted information criterion, Consistency, Algorithm, Selection (genetic algorithm), Mathematics, Forecasting
Abstract: WOS: 000274554900021, Although artificial neural networks (ANN) have been widely used in forecasting time series, the determination of the best model is still a problem that has been studied a lot. Various approaches available in the literature have been proposed in order to select the best model for forecasting in ANN in recent years. One of these approaches is to use a model selection strategy based on the weighted information criterion (WIC). WIC is calculated by summing weighted different selection criteria which measure the forecasting accuracy of an ANN model in different ways. In the calculation of WIC, the weights of different selection criteria are determined heuristically. In this study, these weights are calculated by using optimization in order to obtain a more consistent criterion. Four real time series are analyzed in order to show the efficiency of the improved WIC. When the weights are determined based on the optimization, it is obviously seen that the improved WIC produces better results. (C) 2009 Elsevier B.V. All rights reserved.
Published: 2010
Full Text: View/download PDF

13. A new hybrid approach based on SARIMA and partial high order bivariate fuzzy time series forecasting model

Author: Cagdas Hakan Aladag, Vedide Rezan Uslu, Murat Basaran, Ufuk Yolcu, Erol Egrioglu, Egrioglu, Erol -- 0000-0003-4301-4149, [Aladag, Cagdas Hakan] Hacettepe Univ, Dept Stat, TR-06800 Ankara, Turkey -- [Egrioglu, Erol -- Yolcu, Ufuk -- Uslu, Vedide R.] Ondokuz Mayis Univ, Dept Stat, TR-55139 Kurupelit, Turkey -- [Basaran, Murat A.] Nigde Univ, Dept Math, TR-51000 Nigde, Turkey, 0-Belirlenecek, and Ondokuz Mayıs Üniversitesi
Subjects: Computer science, Feed forward neural networks, Bivariate analysis, Machine learning, computer.software_genre, Fuzzy logic, Order of integration, Bivariate, Artificial Intelligence, Autoregressive integrated moving average, Time series, Box–Jenkins, Series (mathematics), business.industry, Seasonal fuzzy time series, General Engineering, Moving-average model, Computer Science Applications, Box-Jenkins method, Autoregressive model, Artificial intelligence, High order, business, computer, Algorithm, STAR model, Forecasting
Abstract: WOS: 000264528600011, In the literature, there have been many studies using fuzzy time series for the purpose of forecasting. The most studied model is the first order fuzzy time series model. In this model, an observation of fuzzy time series is obtained by using the previous observation. In other words, only the first tagged variable is used when constructing the first order fuzzy time series model. Therefore, this model can not be sufficient for some time series such as seasonal time series which is an important class in time series models. Besides, the time series encountered in real life have not only autoregressive (AR) structure but also moving average (MA) structure. The fuzzy time series models available in the literature are AR structured and are not appropriate for MA structured time series. In this paper, a hybrid approach is proposed in order to analyze seasonal fuzzy time series. The proposed hybrid approach is based on partial high order bivariate fuzzy time series forecasting model which is first introduced in this paper. The order of this model is determined by utilizing Box-Jenkins method. In order to show the efficiency of the proposed hybrid method, real time series are analyzed with this method. The results obtained from the proposed method are compared with the other methods. As a result, it is observed that more accurate results are obtained from the proposed hybrid method. (C) 2008 Elsevier Ltd. All rights reserved.
Published: 2009
Full Text: View/download PDF

14. The Analysis, Optimization, and Simulation of a Two-Stage Tandem Queueing Model with Hyperexponential Service Time at Second Stage

Author: Erdinç Yücesoy, Murat Sağır, Vedat Sağlam, Müjgan Zobu, OMÜ, SAGIR, Murat -- 0000-0001-7567-9327, and [Saglam, Vedat -- Sagir, Murat -- Yucesoy, Erdinc] Ondokuz Mayis Univ, Fac Sci & Arts, Dept Stat, TR-55200 Samsun, Turkey -- [Zobu, Mujgan] Amasya Univ, Fac Sci & Arts, Dept Stat, TR-5000 Amasya, Turkey
Subjects: Queueing theory, Tandem, Article Subject, Computer science, Service time, General Mathematics, lcsh:Mathematics, General Engineering, Variance (accounting), Poisson distribution, lcsh:QA1-939, symbols.namesake, lcsh:TA1-2040, symbols, Layered queueing network, Applied mathematics, Stage (hydrology), lcsh:Engineering (General). Civil engineering (General), Simulation
Abstract: SAGIR, Murat/0000-0001-7567-9327 WOS: 000365228800001 The aim of this paper is to analyze a tandem queueing model with two stages. The arrivals to the first stage are Poisson stream and the service time at this stage is exponential. There is no waiting room at first stage. The service time is hyperexponential and no waiting is allowed at second stage. The transition probabilities and loss probabilities of this model are obtained. In addition, the loss probability at second stage is optimized. Performance measures and the variance of the numbers of customers of this tandem queueing model are found. It is seen that the numbers of customers in first stage and second stage are dependent. Finally we have simulated this queueing model. For different values of parameters, exact values, simulated values, and optimal values of obtained performance measures of this model are numerically shown in tables and graphs.
Published: 2015
Full Text: View/download PDF

15. An Experimental Study For Transforming and Differencing Effects in Multiplicative Neuron Model Artificial Neural Network For Time Series Forecasting

Author: Ilter, Damla, Karaahmetoglu, Elif, Gundogdu, Ozge, Dalar, Ali Zafer, Ondokuz Mayıs Üniversitesi, Loster, T, Pavelka, T, and [Ilter, Damla] Mimar Sinan Fine Arts Univ, Fac Arts & Sci, Dept Stat, TR-34380 Istanbul, Turkey -- [Karaahmetoglu, Elif -- Dalar, Ali Zafer] Ondokuz Mayis Univ, Fac Arts & Sci, Dept Stat, TR-55139 Atakum, Samsun, Turkey -- [Gundogdu, Ozge] Cumhuriyet Univ, Fac Econ & Adm Sci, Dept Econometr, TR-58140 Sivas, Turkey
Subjects: Difference Operator, Multiplicative Neuron Model, Box-Cox Power Transformations, Artificial Neural Networks, Forecasting
Abstract: 8th International Days of Statistics and Economics -- SEP 11-13, 2014 -- Prague, CZECH REPUBLIC, WOS: 000350226700059, Forecasting problems play an important role in time series. In recent years, to solve these problems, many good alternative methods like artificial neural networks have been proposed in the literature. Although the most used artificial neural networks type is multilayer perceptron artificial neural networks, multiplicative neuron model artificial neural networks (MNM-ANNs) have been used to obtain forecasts for a few years. Many of previous studies were used to original series without any transformations such as differencing operation, Box-Cox transformations. Although stationary is an important assumption, previous studies have shown that forecasts obtained from ANNs were employed to non-stationary time series. Box-Cox transformations have been often used to time series because of heteroscedasticity. We used particle swarm optimization (PSO) and artificial bee colony (ABC) algorithms to train MNM-ANNs, and investigated differencing effects of original and transformed data which are obtained from Box-Cox transformations. Istanbul stock exchange (IEX) data sets which are made up of five time series for years between 2009 and 2013 are analyzed. The sets have comprised of first five months for these years. The results are interpreted and discussed. It is shown that transformation operations are useful for forecasting IEX as a result of statistical hypothesis tests., Univ Econ, Dept Stat & Probabil & Dept Microecon, Univ Econ, Fac Business Econ, ESC Rennes Int Sch Business
Published: 2014

16. Control of Traffic Intensity in Hyperexponential and Mixed Erlang Queueing Systems with a Method Based on SPRT

Author: Müjgan Zobu, Vedat Sağlam, OMÜ, and [Zobu, Mujgan] Amasya Univ, Dept Stat, TR-05000 Amasya, Turkey -- [Saglam, Vedat] Ondokuz Mayis Univ, Dept Stat, TR-55139 Samsun, Turkey
Subjects: Queueing theory, Article Subject, Computer science, General Mathematics, Numerical analysis, lcsh:Mathematics, Real-time computing, General Engineering, lcsh:QA1-939, Erlang (unit), Traffic intensity, lcsh:TA1-2040, Sequential probability ratio test, Computer Science::Networking and Internet Architecture, lcsh:Engineering (General). Civil engineering (General), Algorithm
Abstract: WOS: 000322662800001 The control of traffic intensity (rho)is one of the important problems in the study of queueing systems. Rao et al. (1984) developed a method to detect changes in the traffic intensity in queueing systems of the M/G/1 and GI/M/c types based on the Sequential Probability Ratio Test (SPRT). In this paper, SPRT is theoretically investigated for two different phase-type queueing systems which consist of hyperexponential and mixed Erlang. Also, for testing H-0 : rho = rho(0) against H-1 : rho = rho(1),Operating Characteristic (OC) and Average Sample Number (ASN) functions are obtained with numerical methods using multipoint derivative equations according to different situations of alpha and beta type errors. Afterward, numerical illustrations for each model are provided with Matlab programming.
Published: 2013

17. A Two-Stage Model Queueing with No Waiting Line between Channels

Author: Müjgan Zobu, Vedat Sağlam, [Saglam, Vedat] Ondokuz Mayis Univ, Dept Stat, TR-55139 Samsun, Turkey -- [Zobu, Mujgan] Amasya Univ, Dept Stat, TR-05100 Amasya, Turkey, and OMÜ
Subjects: Queueing theory, Article Subject, Computer science, General Mathematics, lcsh:Mathematics, Real-time computing, General Engineering, Poisson distribution, lcsh:QA1-939, symbols.namesake, lcsh:TA1-2040, Line (geometry), symbols, Computer Science::Networking and Internet Architecture, State (computer science), Stage (hydrology), lcsh:Engineering (General). Civil engineering (General), Queue, Algorithm
Abstract: WOS: 000320524600001 We consider a new queuing model with sequential two stations (stages), single server at each station, where no queue is allowed at station 2 and with no restriction at station 1. There is a FCFS service discipline in which the input stream is Poisson having rate lambda. The service time of any customer at server i (i = 1,2) is exponential with parameter mu(i). The state probabilities and loss probability of this model are given. The performance measures are obtained and optimized, and, additionally, the model is simulated. The simulation results, exact results, and optimal results of the performance measures are numerically computed for different parameters.
Published: 2013

18. A new approach based on the optimization of the length of intervals in fuzzy time series

Author: Murat Basaran, Ufuk Yolcu, Cagdas Hakan Aladag, Erol Egrioglu, Vedide Rezan Uslu, Ondokuz Mayıs Üniversitesi, 0-Belirlenecek, Egrioglu, Erol -- 0000-0003-4301-4149, and [Aladag, Cagdas Hakan] Hacettepe Univ, Dept Stat, TR-06800 Ankara, Turkey -- [Egrioglu, Erol -- Yolcu, Ufuk -- Uslu, Vedide R.] Ondokuz Mayis Univ, Dept Stat, Samsun, Turkey -- [Basaran, Murat A.] Nigde Univ, Dept Math, Nigde, Turkey
Subjects: Statistics and Probability, Mathematical optimization, Mean squared error, Fuzzy set, General Engineering, Constrained optimization, Interval (mathematics), Fuzzy logic, fuzzy sets, Artificial Intelligence, length of interval, Golden section search, Successive parabolic interpolation, fuzzy time series, Time series, Algorithm, optimization, Mathematics, Forecasting
Abstract: WOS: 000286099100002, In fuzzy time series analysis, the determination of the interval length is an important issue. In many researches recently done, the length of intervals has been intuitively determined. In order to efficiently determine the length of intervals, two approaches which are based on the average and the distribution have been proposed by Huarng [4]. In this paper, we propose a new method based on the use of a single variable constrained optimization to determine the length of interval. In order to determine optimum length of interval for the best forecasting accuracy, we used aMATLAB function which is employing an algorithm based on golden section search and parabolic interpolation. Mean square error is used as a measure of forecasting accuracy so the objective function value is mean square error value for forecasted observations. The proposed method was employed to forecast the enrollments of the University of Alabama to show the considerable outperforming results.
Published: 2011
Full Text: View/download PDF

19. Preliminary Results on the Preinduction Cervix Status by Shear Wave Elastography

Author: Jorge Torres, María Muñoz, María Del Carmen Porcel, Sofía Contreras, Francisca Sonia Molina, Guillermo Rus, Olga Ocón-Hernández, Juan Melchor, [Torres, Jorge] Univ Granada, Dept Struct Mech, Ultrason Lab TEP 959, Granada 18071, Spain, [Rus, Guillermo] Univ Granada, Dept Struct Mech, Ultrason Lab TEP 959, Granada 18071, Spain, [Torres, Jorge] Inst Invest Biosanitaria Ibs GRANADA, TEC12 Salud Materno Fetal & Elastografia, Granada 18012, Spain, [Sonia Molina, Francisca] Inst Invest Biosanitaria Ibs GRANADA, TEC12 Salud Materno Fetal & Elastografia, Granada 18012, Spain, [Rus, Guillermo] Inst Invest Biosanitaria Ibs GRANADA, TEC12 Salud Materno Fetal & Elastografia, Granada 18012, Spain, [Ocon-Hernandez, Olga] Inst Invest Biosanitaria Ibs GRANADA, TEC12 Salud Materno Fetal & Elastografia, Granada 18012, Spain, [Melchor, Juan] Inst Invest Biosanitaria Ibs GRANADA, TEC12 Salud Materno Fetal & Elastografia, Granada 18012, Spain, [Munoz, Maria] Hosp Univ San Cecilio, Dept Obstet & Gynecol, Maternal Fetal Med Unit, Granada 18016, Spain, [Del Carmen Porcel, Maria] Hosp Univ San Cecilio, Dept Obstet & Gynecol, Maternal Fetal Med Unit, Granada 18016, Spain, [Contreras, Sofia] Hosp Univ San Cecilio, Dept Obstet & Gynecol, Maternal Fetal Med Unit, Granada 18016, Spain, [Sonia Molina, Francisca] Hosp Univ San Cecilio, Dept Obstet & Gynecol, Maternal Fetal Med Unit, Granada 18016, Spain, [Ocon-Hernandez, Olga] Hosp Univ San Cecilio, Dept Obstet & Gynecol, Maternal Fetal Med Unit, Granada 18016, Spain, [Rus, Guillermo] Univ Granada, Excellence Res Unit ModelingNat MNat, Granada 18071, Spain, [Melchor, Juan] Univ Granada, Excellence Res Unit ModelingNat MNat, Granada 18071, Spain, [Melchor, Juan] Univ Granada, Dept Stat & Operat Res, Biostat FQM 235, Granada 18071, Spain, Ministerio de Educacion, Cultura y Deporte grant, Ministerio de Sanidad, Servicios Sociales e Igualdad, Ministerio de Ciencia e Innovacion, Instituto de Salud Carlos III y Fondos Feder, Junta de Andalucia, MCIN/AEI (European Social Fund 'Investing in your future'), and European Regional Development Fund (ERDF)
Subjects: Length, General Mathematics, Shear wave velocity, Quantitative elastography, Recommendations, Reliability, Cervix, Clinical-use, Pregnancy, Labor induction success, Shear wave elastography, Uterine cervix, induction of labor, shear wave elastography, cervix, shear wave velocity, Computer Science (miscellaneous), Prediction, Induction of labor, Engineering (miscellaneous), Wfumb guidelines
Abstract: The mechanical status of the cervix is a key physiological element during pregnancy. By considering a successful induction when the active phase of labor is achieved, mapping the mechanical properties of the cervix could have predictive potential for the management of induction protocols. In this sense, we performed a preliminary assessment of the diagnostic value of using shear wave elastography before labor induction in 54 women, considering the pregnancy outcome and Cesarean indications. Three anatomical cervix regions and standard methods, such as cervical length and Bishop score, were compared. To study the discriminatory power of each diagnostic method, a receiver operating characteristic curve was generated. Differences were observed using the external os region and cervical length in the failure to enter the active phase group compared to the vaginal delivery group (p < 0.05). The area under the ROC curve resulted in 68.9%, 65.2% and 67.2% for external os, internal os and cervix box using elastography, respectively, compared to 69.5% for cervical length and 62.2% for Bishop score. External os elastography values have shown promise in predicting induction success. This a priori information could be used to prepare a study with a larger sample size, which would reduce the effect of any bias selection and increase the predictive power of elastography compared to other classical techniques., Ministerio de Educacion, Cultura y Deporte grant DPI2017-83859-R DPI2014-51870-R UNGR15-CE-3664 EQC2018-004508-P, Spanish Government DTS15/00093 PI16/00339, Instituto de Salud Carlos III, Spanish Government, European Commission PID2020-115372RB-I00 PYC20 RE 072 UGR, Instituto de Salud Carlos III y Fondos Feder, Junta de Andalucia PI-0107-2017 PIN-0030-2017 IE2017-5537 B-TEP-026-UGR18 P18-RT-1653, MCIN/AEI (European Social Fund "Investing in your future") PRE2018-086085, European Commission P18-RT-1653 SOMM17/6109/UGR
Published: 2022
Full Text: View/download PDF

20. A new approach for determining the length of intervals for fuzzy time series

Author: Murat Basaran, Erol Egrioglu, Ufuk Yolcu, Vedide Rezan Uslu, Cagdas Hakan Aladag, Egrioglu, Erol -- 0000-0003-4301-4149, [Yolcu, Ufuk -- Egrioglu, Erol -- Uslu, Vedide R.] Ondokuz Mayis Univ, Dept Stat, TR-55139 Samsun, Turkey -- Nigde Univ, Dept Math, TR-51200 Nigde, Turkey -- [Aladag, Cagdas H.] Univ Hacettepe, Dept Stat, TR-06800 Ankara, Turkey, 0-Belirlenecek, and Ondokuz Mayıs Üniversitesi
Subjects: Optimization, Mathematical optimization, Fuzzy sets, Series (mathematics), Fuzzy set, Constrained optimization, Interval (mathematics), Fuzzy logic, Order of integration, Identification (information), Length of interval, Time series, Algorithm, Software, Fuzzy time series, Mathematics, Forecasting
Abstract: WOS: 000262888100021, In the implementations of fuzzy time series forecasting, the identification of interval lengths has an important impact on the performance of the procedure. However, the interval length has been chosen arbitrarily in many papers. Huarng developed a new approach which is called ratio-based lengths of intervals in order to identify the length of intervals. In our paper, we propose a new approach which uses a single-variable constrained optimization to determine the ratio for the length of intervals. The proposed approach is applied to the two well-known time series, which are enrollment data at The University of Alabama and inventory demand data. The obtained results are compared to those of other methods. The proposed method produces more accurate predictions for the future values of used time series. (c) 2008 Elsevier B.V. All rights reserved.
Published: 2009

21. Forecasting in high order fuzzy times series by using neural networks to define fuzzy relations

Author: Erol Egrioglu, Cagdas Hakan Aladag, Vedide Rezan Uslu, Ufuk Yolcu, Murat Basaran, Egrioglu, Erol -- 0000-0003-4301-4149, [Aladag, Cagdas H.] Univ Hacettepe, Dept Stat, TR-06800 Ankara, Turkey -- [Basaran, Murat A.] Nigde Univ, Dept Math, TR-51000 Nigde, Turkey -- [Egrioglu, Erol -- Yolcu, Ufuk -- Uslu, Vedide R.] Ondokuz Mayis Univ, Dept Stat, TR-55139 Samsun, Turkey, Ondokuz Mayıs Üniversitesi, and 0-Belirlenecek
Subjects: Adaptive neuro fuzzy inference system, Fuzzy classification, Neuro-fuzzy, General Engineering, computer.software_genre, Fuzzy relation, Fuzzy logic, Defuzzification, High order fuzzy time series, Computer Science Applications, Artificial Intelligence, Fuzzy set, Fuzzy number, Fuzzy set operations, Fuzzy associative matrix, Data mining, computer, Neural networks, Mathematics, Forecasting
Abstract: WOS: 000263584100009, A given observation in time series does not only depend on preceding one but also previous ones in general. Therefore, high order fuzzy time series approach might obtain better forecasts than does first order fuzzy time series approach. Defining fuzzy relation in high order fuzzy time series approach are more complicated than that in first order fuzzy time series approach. A new proposed approach, which uses feed forward neural networks to define fuzzy relation in high order fuzzy time series, is introduced in this paper. The new proposed approach is applied to well-known enrollment data for the University of Alabama and obtained results are compared with other methods proposed in the literature. It is found that the proposed method produces better forecasts than the other methods. (c) 2008 Elsevier Ltd. All rights reserved.
Published: 2009

22. A New Approach Based on Artificial Neural Networks for High Order Bivariate Fuzzy Time Series

Author: Erol Egrioglu, V. Rezan Uslu, Ufuk Yolcu, M. A. Basaran, Aladag C. Hakan, Mehnen, J, Koppen, M, Saad, A, Tiwari, A, Egrioglu, Erol -- 0000-0003-4301-4149, [Egrioglu, Erol -- Uslu, V. Rezan -- Yolcu, Ufuk] Ondokuz Mayis Univ, Dept Stat, TR-55139 Samsun, Turkey -- [Basaran, M. A.] Nigde Univ, Dept Math, TR-51000 Nigde, Turkey -- [Hakan, Aladag C.] Hacettepe Univ, Dept Stat, TR-06800 Ankara, Turkey, Ondokuz Mayıs Üniversitesi, and 0-Belirlenecek
Subjects: 0-Belirlenecek
Abstract: 13th World Conference on Soft Computing in Industrial Application -- 2008 -- ELECTR NETWORK, WOS: 000269657800026, When observations of time series are defined linguistically or do not follow the assumptions required for time series theory, the classical methods of time series analysis do not cope with fuzzy numbers and assumption violations. Therefore, forecasts are not reliable. [8], [9] gave a definition of fuzzy time series which have fuzzy observations and proposed a forecast method for it. In recent years, many researches about univariate fuzzy time series have been conducted. In [6], [5], [7], [4] and [10] bivariate fuzzy time series approaches have been proposed. In this study, a new method for high order bivariate fuzzy time series in which fuzzy relationships are determined by artificial neural networks (ANN) is proposed and the real data application of the proposed method is presented., World Federat Soft Comp, IEEE Ind Applicat Soc, IEEE UKRI Sect, Elsevier
Published: 2009

23. A new approach based on artificial neural networks for high order multivariate fuzzy time series

Author: Vedide Rezan Uslu, Cagdas Hakan Aladag, Erol Egrioglu, Murat Basaran, Ufuk Yolcu, 0-Belirlenecek, Egrioglu, Erol -- 0000-0003-4301-4149, [Aladag, Cagdas Hakan] Hacettepe Univ, Dept Stat, TR-06800 Ankara, Turkey -- [Egrioglu, Erol -- Yolcu, Ufuk -- Uslu, Vedide R.] Ondokuz Mayis Univ, Dept Stat, TR-55139 Samsun, Turkey -- [Basaran, Murat A.] Nigde Univ, Dept Math, TR-51000 Nigde, Turkey, and Ondokuz Mayıs Üniversitesi
Subjects: Multivariate statistics, Fuzzy classification, Neuro-fuzzy, Computer science, computer.software_genre, Fuzzy logic, Defuzzification, Artificial Intelligence, Fuzzy number, Adaptive neuro fuzzy inference system, Artificial neural network, Artificial neural networks, business.industry, Multivariate fuzzy time series approaches, General Engineering, Univariate, Fuzzy control system, Expert system, Computer Science Applications, Fuzzy set operations, Artificial intelligence, Data mining, business, computer, Fuzzy time series, Forecasting
Abstract: WOS: 000266851000044, Fuzzy time series methods have been recently becoming very popular in forecasting. These methods can be categorized into two subclasses that are univariate and multivariate approaches. It is a known fact that real time series data can actually be affected by many factors. In this case, the using multivariate fuzzy time series forecasting model can be more reasonable in order to get more accurate forecasts. To obtain fuzzy forecasts when multivariate fuzzy time series approach is adopted, the most applied method is using tables of fuzzy relations. However, employing this method is a computationally though task. In this study, we introduce a new method that does not require using fuzzy logic relation tables in order to determine fuzzy relationships. Instead, a feed forward artificial neural network is employed to determine fuzzy relationships. The proposed method is applied to the time series data of the total number of annual car road accidents casualties in Belgium from 1974 to 2004 and a comparison is made between our proposed method and the methods proposed by Jilani and Burney [Jilani, T. A., & Burney, S. M. A. (2008). Multivariate stochastic fuzzy forecasting models. Expert Systems with Applications, 35, 691-700] and Lee et al. [Lee, L.-W., Wang, L.-H., Chen, S.-M., & Leu, Y.-H. (2006). Handling forecasting problems based on two factors high order fuzzy time series. IEEE Transactions on Fuzzy Systems, 14, 468-477]. (C) 2009 Elsevier Ltd. All rights reserved.
Published: 2009

24. Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI

Author: Giuseppe De Luca, Pierre Deharo, Pierfrancesco Agostoni, Gabriele Gabrielli, Francisco Bosa Ojeda, Ylitalo Antti, Lisette Okkels Jensen, Bor Wilbert, Luigi Vignali, Fortunato Scotto Di Uccio, Dariusz Dudek, Marco Boccalatte, Monica Verdoia, Edouard Benit, Gianni Casella, Heidi Lehtola, Alessandra Scoccia, Tim Kinnaird, Massimo Siviglia, Raul Moreno, Vladimir Ganyukov, Arpad Lux, Mika Laine, Adrian P. Banning, Santiago Camacho-Freiere, Guido Parodi, José Moreu, Michał Kidawa, Miha Cercek, Victor Becerra, Stephane Manzo, Elvin Kedhi, Marija Vavlukis, Filippo Zilio, Ciro De Simone, Nikola Bakraceski, Xavier Carrillo, Giuseppe Uccello, Maurizio Menichelli, Gerard Rourai Ferrer, Dimitrios Alexopoulos, Benjamin Faurie, Jurriën M. ten Berg, Lucia Marinucci, Juan Sanchis Forés, Giovanni Amoroso, Sébastien Levesque, Bernardo Tuccillo, Enrico Fabris, Peter Ludman, Rui Campante Teles, Wojtek Wojakowski, Leonardo Spedicato, Lucian Calmac, Yves Cottin, Maurits T. Dirksen, Petr Kala, Thomas W Johnson, Xacobe Flores Rios, Gianluca Caiazzo, Clemens van Birgelen, Francesco Versaci, Alexander Ijsselmuiden, Luca Donazzan, Kees-Jan Royaards, Adriaan O. Kraaijeveld, Alejandro Gutierrez Barrios, Gennaro Galasso, Vincenzo Guiducci, Julinda Mehilli, Giuseppe Cirrincione, Andrea Santucci, Giuliana Cortese, José Luis Díez Gil, Iñigo Lozano Martínez-Luengas, Bruno Scheller, Periklis Davlouros, Tomas Kovarnik, Arturo García-Touchard, Pieter C. Smits, De Luca, G., Verdoia, M., Cercek, M., Jensen, L. O., Vavlukis, M., Calmac, L., Johnson, T., Ferrer, G. R., Ganyukov, V., Wojakowski, W., Kinnaird, T., van Birgelen, C., Cottin, Y., Ijsselmuiden, A., Tuccillo, B., Versaci, F., Royaards, K. -J., Berg, J. T., Laine, M., Dirksen, M., Siviglia, M., Casella, G., Kala, P., Diez Gil, J. L., Banning, A., Becerra, V., De Simone, C., Santucci, A., Carrillo, X., Scoccia, A., Amoroso, G., Lux, A., Kovarnik, T., Davlouros, P., Mehilli, J., Gabrielli, G., Rios, X. F., Bakraceski, N., Levesque, S., Cirrincione, G., Guiducci, V., Kidawa, M., Spedicato, L., Marinucci, L., Ludman, P., Zilio, F., Galasso, G., Fabris, E., Menichelli, M., Garcia-Touchard, A., Manzo, S., Caiazzo, G., Moreu, J., Fores, J. S., Donazzan, L., Vignali, L., Teles, R., Benit, E., Agostoni, P., Bosa Ojeda, F., Lehtola, H., Camacho-Freiere, S., Kraaijeveld, A., Antti, Y., Boccalatte, M., Deharo, P., Martinez-Luengas, I. L., Scheller, B., Alexopulos, D., Moreno, R., Kedhi, E., Uccello, G., Faurie, B., Gutierrez Barrios, A., Di Uccio, F. S., Wilbert, B., Smits, P., Cortese, G., Parodi, G., Dudek, D., banning, adrian/0000-0002-2842-7861, GUIDUCCI, VINCENZO/0000-0002-0833-2785, vavlukis, marija/0000-0002-4479-6691, Bor, Willem L/0000-0002-3253-5961, DAVLOUROS, PERIKLIS/0000-0002-1439-1992, Uccello, Giuseppe/0000-0002-6163-8468, Kidawa, Michal/0000-0002-5000-6561, [De Luca, Giuseppe] Univ Piemonte Orientale, Div Cardiol, Azienda Osped Univ Maggiore Carita, Novara, Italy, [Verdoia, Monica] Osped Inferm Biella, ASL Biella, Div Cardiol, Biella, Italy, [Cercek, Miha] Univ Med Ctr, Ctr Intens Internal Med, Ljubljana, Slovenia, [Jensen, Lisette Okkels] Odense Univ Hosp, Div Cardiol, Odense, Denmark, [Vavlukis, Marija] Ss Cyril & Methodius Univ, Med Fac, Univ Clin Cardiol, Skopje, North Macedonia, [Calmac, Lucian] Clin Emergency Hosp Bucharest, Bucharest, Romania, [Johnson, Tom] Univ Hosp Bristol NHSFT, Bristol Heart Inst, Div Cardiol, Bristol, Avon, England, [Johnson, Tom] Univ Bristol, Bristol, Avon, England, [Ferrer, Gerard Rourai] Hosp Univ Bellvitge, Heart Dis Inst, Intervent Cardiol Unit, Barcelona, Spain, [Ganyukov, Vladimir] State Res Inst Complex Issues Cardiovasc Dis, Div Cardiol, Kemerovo, Russia, [Wojakowski, Wojtek] Med Univ Silezia, Div Cardiol, Katowice, Poland, [Kinnaird, Tim] Univ Hosp Wales, Div Cardiol, Cardiff, Wales, [van Birgelen, Clemens] Thoraxctr Twente, Dept Cardiol, Med Spectrum Twente, Enschede, Netherlands, [Cottin, Yves] Univ Hosp, Div Cardiol, Dijon, France, [IJsselmuiden, Alexander] Amphia Hosp, Div Cardiol, Breda, Netherlands, [Tuccillo, Bernardo] Osped Mare, Div Cardiol, Naples, Italy, [Di Uccio, Fortunato Scotto] Osped Mare, Div Cardiol, Naples, Italy, [Versaci, Francesco] Osped Santa Maria Goretti, Div Cardiol, Latina, Italy, [Royaards, Kees-Jan] Maasstad Ziekenhuis, Div Cardiol, Rotterdam, Netherlands, [Smits, Pieter] Maasstad Ziekenhuis, Div Cardiol, Rotterdam, Netherlands, [Ten Berg, Jurrien] St Antonius Hosp, Div Cardiol, Nieuwegein, Netherlands, [Wilbert, Bor] St Antonius Hosp, Div Cardiol, Nieuwegein, Netherlands, [Laine, Mika] Helsinki Univ Cent Hosp, Div Cardiol, Helsinki, Finland, [Dirksen, Maurits] Northwest Clin, Div Cardiol, Alkmaar, Netherlands, [Siviglia, Massimo] Osped Riuniti Reggio Calabria, Div Cardiol, Reggio Di Calabria, Italy, [Casella, Gianni] Osped Maggiore Bologna, Div Cardiol, Bologna, Italy, [Kala, Petr] Masaryk Univ, Univ Hosp Brno, Med Fac, Brno, Czech Republic, [Diez Gil, Jose Luis] H Univ & Politecn La Fe, Valencia, Spain, [Banning, Adrian] John Radcliffe Hosp, Oxford, England, [Becerra, Victor] Hosp Clin Univ Virgen Victoria, Malaga, Spain, [De Simone, Ciro] Clin Villa Fiori, Div Cardiol, Acerra, Italy, [Santucci, Andrea] Osped Santa Maria Misericordia, Perugia, Italy, [Carrillo, Xavier] Hosp Germans Triasi Pujol, Badalona, Spain, [Scoccia, Alessandra] Osped St Anna, Div Cardiol, Ferrara, Italy, [Amoroso, Giovanni] Onze Lieve Vrouwe Gasthuis OLVG, Amsterdam, Netherlands, [Lux, Arpad] Mastricht Univ, Med Ctr, Maastricht, Netherlands, [Kovarnik, Tomas] Charles Univ Hosp, Prague, Czech Republic, [Davlouros, Periklis] Patras Univ Hosp, Invas Cardiol & Congenital Heart Dis, Patras, Greece, [Mehilli, Julinda] Ludwig Maximilians Univ Munchen, Univ Hosp Munich, Munich, Germany, [Gabrielli, Gabriele] Azienda Osped Univ, Intervent Cardiol Unit, Osped Riuniti, Ancona, Italy, [Rios, Xacobe Flores] Complexo Hosp Univ La Coruna, La Coruna, Spain, [Bakraceski, Nikola] Ctr Cardiovasc Dis, Ohrid, North Macedonia, [Levesque, Sebastien] CHU Poitiers, Univ Hosp, Poitiers, France, [Cirrincione, Giuseppe] Osped Civ Arnas, Div Cardiol, Palermo, Italy, [Guiducci, Vincenzo] AUSL IRCCS, Reggio Emilia, Italy, [Kidawa, Michal] Med Univ Lodz, Cent Hosp, Lodz, Poland, [Spedicato, Leonardo] Osped Santa Maria Misericordia, Div Cardiol, Udine, Italy, [Marinucci, Lucia] Osped Riuniti Marche Nord, Div Cardiol, Azienda Osped, Pesaro, Italy, [Ludman, Peter] Univ Hosp Birmingham, Birmingham, W Midlands, England, [Zilio, Filippo] Osped Santa Chiara, Trento, Italy, [Galasso, Gennaro] Osped San Giovanni Dio Ruggi Aragona, Div Cardiol, Salerno, Italy, [Fabris, Enrico] Univ Ospedali Riuniti, Azienda Osped, Trieste, Italy, [Menichelli, Maurizio] Osped F Spaziani, Div Cardiol, Frosinone, Italy, [Garcia-Touchard, Arturo] Hosp Puerta Hierro, Div Cardiol, Majadahonda, Spain, [Manzo, Stephane] Paris 07 Univ, CHU Lariboisiere, AP HP, Div Cardiol,INSERM,UMRS 942, Paris, France, [Caiazzo, Gianluca] Osped G Moscati, Div Cardiol, Aversa, Italy, [Moreu, Jose] Complejo Hosp Toledo, Div Cardiol, Toledo, Spain, [Sanchis Fores, Juan] Hosp Clin Univ Valencia, Div Cardiol, Valencia, Spain, [Donazzan, Luca] Osped S Maurizio Bolzano, Div Cardiol, Bolzano, Italy, [Vignali, Luigi] Azienda Osped Sanitaria, Intervent Cardiol Unit, Parma, Italy, [Teles, Rui] Hosp Santa Cruz, Div Cardiol, CHLO Carnaxide, Lisbon, Portugal, [Benit, Edouard] Jessa Ziekenhuis, Div Cardiol, Hasselt, Belgium, [Agostoni, Pierfrancesco] Ziekenhuis Netwerk Antwerpen ZNA Middelheim, Div Cardiol, Antwerp, Belgium, [Bosa Ojeda, Francisco] Hosp Univ Canarias, Div Cardiol, Santa Cruz De Tenerife, Spain, [Lehtola, Heidi] Oulu Univ Hosp, Div Cardiol, Oulu, Finland, [Camacho-Freiere, Santiago] Juan Ramon Jimenez Hosp, Div Cardiol, Huelva, Spain, [Kraaijeveld, Adriaan] UMC Utrecht, Div Cardiol, Utrecht, Netherlands, [Antti, Ylitalo] Univ Hosp, Heart Ctr, Div Cardiol, Turku, Finland, [Boccalatte, Marco] Osped Santa Maria Grazie, Div Cardiol, Pozzuoli, Italy, [Deharo, Pierre] Aix Marseille Univ, CHU Timone, Div Cardiol, Marseille, France, [Lozano Martinez-Luengas, Inigo] Hosp Cabuenes, Div Cardiol, Gijon, Spain, [Scheller, Bruno] Univ Saarland, Div Cardiol Clin & Expt Intervent Cardiol, Homburg, Germany, [Alexopoulos, Dimitrios] Attikon Univ Hosp, Div Cardiol, Athens, Greece, [Moreno, Raul] Hosp Paz, Div Cardiol, Madrid, Spain, [Kedhi, Elvin] St Jan Hosp, Div Cardiol, Brugge, Belgium, [Uccello, Giuseppe] Osped A Manzoni Lecco, Div Cardiol, Lecce, Italy, [Faurie, Benjamin] Grp Hosp Mutualiste Grenoble, Div Cardiol, Grenoble, France, [Gutierrez Barrios, Alejandro] Hosp Puerta Mar, Div Cardiol, Cadiz, Spain, [Cortese, Giuliana] Univ Padua, Dept Stat Sci, Padua, Italy, [Parodi, Guido] Azienda Osped Univ Sassari, Sassari, Italy, [Dudek, Dariusz] Jagiellonian Univ Med Coll, Inst Cardiol, Krakow, Poland, RS: Carim - H01 Clinical atrial fibrillation, and Cardiologie
Subjects: Male, Internationality, medical decision-making, medicine.medical_treatment, 030204 cardiovascular system & hematology, Rate ratio, COVID-19 (coronavirus), Settore MED/06, 0302 clinical medicine, Pandemic, Percutaneous Coronary Intervention/statistics & numerical data, Medicine, Viral, 030212 general & internal medicine, Myocardial infarction, Registries, Acute myocardial-infarction, Original Investigation, STEMI, ST-segment elevation myocardial infarction, Middle Aged, 3. Good health, Europe, fibrinolysis, Female, COVID-19, primary angioplasty, STEMI, Aged, Humans, Percutaneous Coronary Intervention, Retrospective Studies, ST Elevation Myocardial Infarction, Coronavirus Infections, Pandemics, Pneumonia, Viral, Cardiology and Cardiovascular Medicine, Editorial Comment, ACUTE MYOCARDIAL-INFARCTION, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Primary angioplasty, IRR, incidence rate ratio, Europe/epidemiology, 03 medical and health sciences, Betacoronavirus, cardiovascular diseases, Mortality, PCI, percutaneous coronary intervention, DES, drug-eluting stent(s), business.industry, ST Elevation Myocardial Infarction/mortality, PPCI, primary PCI, SARS-CoV-2, MORTALITY, Percutaneous coronary intervention, Retrospective cohort study, Pneumonia, medicine.disease, Confidence interval, ST-segment elevation myocardial infarction, CI, confidence interval, Emergency medicine, COVID-19, STEMI, primary angioplasty, ACS, acute coronary syndrome, business
Abstract: Background The fear of contagion during the coronavirus disease-2019 (COVID-19) pandemic may have potentially refrained patients with ST-segment elevation myocardial infarction (STEMI) from accessing the emergency system, with subsequent impact on mortality. Objectives The ISACS-STEMI COVID-19 registry aims to estimate the true impact of the COVID-19 pandemic on the treatment and outcome of patients with STEMI treated by primary percutaneous coronary intervention (PPCI), with identification of “at-risk” patient cohorts for failure to present or delays to treatment. Methods This retrospective registry was performed in European high-volume PPCI centers and assessed patients with STEMI treated with PPPCI in March/April 2019 and 2020. Main outcomes are the incidences of PPCI, delayed treatment, and in-hospital mortality. Results A total of 6,609 patients underwent PPCI in 77 centers, located in 18 countries. In 2020, during the pandemic, there was a significant reduction in PPCI as compared with 2019 (incidence rate ratio: 0.811; 95% confidence interval: 0.78 to 0.84; p, Central Illustration
Published: 2020
Full Text: View/download PDF

25. Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib

Author: Roland Van Velthoven, Sandrine Marreaud, Peter F.A. Mulders, Christian U. Blank, Sylvie Rottey, Sandra Collette, Johannes V. Van Thienen, Laurence Collette, Thomas Powles, Axel Bex, Lori Wood, Harm H.H.E. Van Melick, Jean Baptiste Lattouf, Igle J. de Jong, John B. A. G. Haanen, John Wagstaff, Bertrand Tombal, Michael A.S. Jewett, M.P. Laguna, Maureen J.B. Aarts, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - (SLuc) Service d'urologie, Bex, Axel, van Thienen, Johannes V., Blank, Christian U., Haanen, John Netherlands Canc Inst, Amsterdam, Netherlands, Mulders, Peter Catholic Univ Nijmegen, Dept Urol, Nijmegen, Netherlands, Jewett, Michael Princess Margaret Hosp, Dept Urol, Toronto, ON, Canada, Wagstaff, John Cardiff Hosp, Dept Oncol, Cardiff, S Glam, Wales, van Velthoven, Roland Inst Jules Bordet, Dept Urol, Brussels, Belgium, Laguna, Maria del Pilar Istanbul Medipol Univ, Dept Urol, Istanbul, Turkey, Wood, Lori QEII Hlth Sci Ctr, Div Med Oncol, Halifax, NS, Canada, van Melick, Harm H. E. St Antonius Hosp, Dept Urol, Nieuwegein, Netherlands, Aarts, Maureen J. Maastricht Univ, Med Ctr, Dept Oncol, Maastricht, Netherlands, Lattouf, J. B. Univ Montreal, Hosp Ctr, Dept Surg Urol, Quebec City, ON, Canada, Powles, Thomas Royal Free Hosp, Dept Oncol, London, England, Powles, Thomas Queen Mary Univ, London, England, de Jong, Igle Jan Univ Groningen, Univ Med Ctr Groningen, Dept Urol, Groningen, Netherlands, Rottey, Sylvie Ghent Univ Hosp, Dept Med Oncol, Ghent, Belgium, Tombal, Bertrand Clin Univ St Luc, Dept Urol, Brussels, Belgium, Marreaud, Sandrine, Collette, Sandra, Collette, Laurence European Org Res Treatment Canc, Dept Stat, Brussels, Belgium, Collette, Sandra Bristol Myers Squibb, Brussels, Belgium, Uluslararası Tıp Fakültesi, Interne Geneeskunde, MUMC+: MA Medische Oncologie (9), and RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy
Subjects: Male, Cancer Research, Time Factors, medicine.medical_treatment, urologic and male genital diseases, Nephrectomy, law.invention, 0302 clinical medicine, TARGETED THERAPY, Randomized controlled trial, law, Renal cell carcinoma, Clinical endpoint, Sunitinib, 030212 general & internal medicine, Original Investigation, Hazard ratio, Cytoreduction Surgical Procedures, Middle Aged, RADICAL NEPHRECTOMY, CANCER, Kidney Neoplasms, Neoadjuvant Therapy, Progression-Free Survival, Europe, Editorial Commentary, Oncology, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Disease Progression, SURVIVAL, Female, Erratum, medicine.drug, medicine.medical_specialty, Canada, RESECTION, Urology, Antineoplastic Agents, PLANNED NEPHRECTOMY, Drug Administration Schedule, 03 medical and health sciences, MORBIDITY, All institutes and research themes of the Radboud University Medical Center, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], medicine, Humans, Radiology, Nuclear Medicine and imaging, Progression-free survival, Carcinoma, Renal Cell, Protein Kinase Inhibitors, Aged, business.industry, MORTALITY, Généralités, medicine.disease, EFFICACY, Clinical trial, INTERFERON-ALPHA, business
Abstract: Importance: In clinical practice, patients with primary metastatic renal cell carcinoma (mRCC) have been offered cytoreductive nephrectomy (CN) followed by targeted therapy, but the optimal sequence of surgery and systemic therapy is unknown. Objective: To examine whether a period of sunitinib therapy before CN improves outcome compared with immediate CN followed by sunitinib. Design, Setting, and Participants: This randomized clinical trial began as a phase 3 trial on July 14, 2010, and continued until March 24, 2016, with a median follow-up of 3.3 years and a clinical cutoff date for this report of May 5, 2017. Patients with mRCC of clear cell subtype, resectable primary tumor, and 3 or fewer surgical risk factors were studied. Interventions: Immediate CN followed by sunitinib therapy vs treatment with 3 cycles of sunitinib followed by CN in the absence of progression followed by sunitinib therapy. Main Outcomes and Measures: Progression-free survival was the primary end point, which needed a sample size of 458 patients. Because of poor accrual, the independent data monitoring committee endorsed reporting the intention-to-treat 28-week progression-free rate (PFR) instead. Overall survival (OS), adverse events, and postoperative progression were secondary end points. Results: The study closed after 5.7 years with 99 patients (80 men and 19 women; mean [SD] age, 60 [8.5] years). The 28-week PFR was 42% in the immediate CN arm (n = 50) and 43% in the deferred CN arm (n = 49) (P =.61). The intention-to-treat OS hazard ratio of deferred vs immediate CN was 0.57 (95% CI, 0.34-0.95; P =.03), with a median OS of 32.4 months (95% CI, 14.5-65.3 months) in the deferred CN arm and 15.0 months (95% CI, 9.3-29.5 months) in the immediate CN arm. In the deferred CN arm, 48 of 49 patients (98%; 95% CI, 89%-100%) received sunitinib vs 40 of 50 (80%; 95% CI, 67%-89%) in the immediate arm. Systemic progression before planned CN in the deferred CN arm resulted in a per-protocol recommendation against nephrectomy in 14 patients (29%; 95% CI, 18%-43%). Conclusions and Relevance: Deferred CN did not improve the 28-week PFR. With the deferred approach, more patients received sunitinib and OS results were higher. Pretreatment with sunitinib may identify patients with inherent resistance to systemic therapy before planned CN. This evidence complements recent data from randomized clinical trials to inform treatment decisions in patients with primary clear cell mRCC requiring sunitinib. Trial Registration: ClinicalTrials.gov identifier: NCT01099423., SCOPUS: cp.j, info:eu-repo/semantics/published
Published: 2019

26. Cardiac Effects of a Rowing Training Program in Breast Cancer Survivors

Author: Ismael Gálvez-Fernández, José Carlos Fernández-García, Juan Gavala-González, Pere Mercadé-Melé, Universidad de Sevilla. Departamento de Educación Física y Deporte, [Gavala-Gonzalez, Juan] Univ Seville, Dept Phys Educ & Sports, Seville 41013, Spain, [Galvez-Fernandez, Ismael] Univ Malaga, Dept Didact Languages Arts & Sport, Andalucia Tech, IBIMA, Malaga 29010, Spain, [Carlos Fernandez-Garcia, Jose] Univ Malaga, Dept Didact Languages Arts & Sport, Andalucia Tech, IBIMA, Malaga 29010, Spain, [Mercade-Mele, Pere] Univ Malaga, Dept Stat & Econometr, Andalucia Tech, Malaga 29010, Spain, 'Researching in Sport Sciences' research group of the Andalusian Research Plan, [Gavala-González,J] Department of Physical Education and Sports, University of Seville, Seville, Spain. [Gálvez-Fernández,I, Fernández-García,JC] Department of Didactics of Languages, Arts and Sport, University of Malaga, Andalucía-Tech, IBIMA, Malaga, Spain. [Mercadé-Melé,P] Department of Statistics and Econometrics, University of Malaga, Andalucía-Tech, Malaga, Spain., and This research was funded by the 'Researching in Sport Sciences' research group (CTS-563) of the Andalusian Research Plan.
Subjects: Calidad de vida, medicine.medical_treatment, Geography, Planning and Development, Rowing, physical activity, Renewable energy sources, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], 0302 clinical medicine, Supervivientes de cáncer, GE1-350, 030212 general & internal medicine, Mastectomy, education.field_of_study, Environmental effects of industries and plants, Metaanalysis, Ejercicio físico, Health, Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Quality of Life [Medical Subject Headings], 030220 oncology & carcinogenesis, Neoplasias de la mama, Cardiology, Quality of life, Risk, Cardiac function curve, medicine.medical_specialty, Population, Diastole, TJ807-830, Management, Monitoring, Policy and Law, TD194-195, rowing training, Dragon boat, breast cancer survivor, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Mastectomy::Mastectomy, Simple [Medical Subject Headings], 03 medical and health sciences, Internal medicine, Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Cardiovascular Physiological Phenomena::Hemodynamics::Blood Pressure [Medical Subject Headings], Heart rate, Anatomy::Cardiovascular System [Medical Subject Headings], medicine, Aerobic exercise, Women, Training effects, Mastectomía, education, Exercise, Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms [Medical Subject Headings], Physical activity, Renewable Energy, Sustainability and the Environment, business.industry, Breast cancer survivor, Environmental sciences, Blood pressure, Check Tags::Female [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Mastectomy [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Vital Signs::Heart Rate [Medical Subject Headings], Physical-activity, business, Rowing training, training effects
Abstract: The aim of this study was to determine whether a rowing training program could improve cardiac function in women (n = 28) with the mean age of 52.30 ± 3.78 years who survived breast cancer (stage 1: 4.55%, 2: 36.36%, 3: 54.54%, and 4: 4.55%) diagnosed 4.68 ± 3.00 years previously and underwent subsequent surgery (preservation: 56.52%, total mastectomy: 39.13%, and double mastectomy: 4.35%). Participants completed a 12-week training program consisting of three weekly sessions lasting 60–90 min with a progressive intensity increase according to the Börg scale. The assessments performed were blood pressure and pulse measurements both at rest and after performing the six-minute walk test to collect data on cardiac behavior and aerobic performance. The results showed statistically significant differences in cardiovascular system efficiency measured on the basis of heart rate both before (−12.63 ± 14.68 bpm) and after the six-minute walk test (−11.46 ± 28.39 bpm), increase in the distance achieved in the aerobic endurance test (51.56 ± 48.26 m) as well as decrease in diastolic (−13.6 ± 7.85 mm Hg) and systolic (−6.60 ± 9.10 mm Hg) blood pressure. These results suggest that rowing training programs could be a strategy to consider in this population for the benefits observed in heart rate, blood pressure and aerobic performance, which would lead to improved general health and quality of life.
Published: 2021

27. Modeling Interactions among Migration, Growth and Pressure in Tumor Dynamics

Author: Juan Campos, Juan José Soler, Juan Melchor, Beatriz Blanco, [Blanco, Beatriz] Univ Granada, Dept Struct Mech, Granada 18071, Spain, [Blanco, Beatriz] Ibs GRANADA, Inst Invest Biosanitaria, Granada 18012, Spain, [Melchor, Juan] Ibs GRANADA, Inst Invest Biosanitaria, Granada 18012, Spain, [Campos, Juan] Univ Granada, Fac Ciencias, Dept Matemat Aplicada, Granada 18071, Spain, [Soler, Juan] Univ Granada, Fac Ciencias, Dept Matemat Aplicada, Granada 18071, Spain, [Campos, Juan] Univ Granada, Res Unit Modelling Nat MNat, Granada 18071, Spain, [Melchor, Juan] Univ Granada, Res Unit Modelling Nat MNat, Granada 18071, Spain, [Soler, Juan] Univ Granada, Res Unit Modelling Nat MNat, Granada 18071, Spain, [Melchor, Juan] Univ Granada, Dept Stat & Operat Res, Granada 18071, Spain, MINECO-Feder (Spain), Junta de Andalucia (Spain), Instituto de Salud Carlos III, Ministry of Science, Innovation and Universities of Spain, Consejeria de Economia, Conocimiento, Empresas y Universidad, European Regional Development Fund (ERDF), [Blanco,B] Department of Structural Mechanics, University of Granada, Granada, Spain. [Blanco,B, Melchor,J] Instituto de Investigación Biosanitaria, ibs.GRANADA, Granada, Spain. [Campos,J, Soler,J] Departamento de Matemática Aplicada, Facultad de Ciencias, Universidad de Granada, Granada, Spain. [Campos,J, Melchor,J, Soler,J] Research Unit 'Modelling Nature' (MNat), Universidad de Granada, Granada, Spain., and This paper has been partially supported by the MINECO-Feder (Spain) research grant num bers RTI2018-098850-B-I00 (J.C., J.S.) & EQC2018-004508-P (B.B., J.M.), the Junta de Andalucía (Spain) Projects PY18-RT-2422 (J.C., J.S.), A-FQM-311-UGR18 (J.C., J.S.) & IE2017-5537 (B.B., J.M.), and by the Instituto de Salud Carlos III, project number DTS17/00087 (J.M., J.S.). This study was also funded by Ministry of Science, Innovation and Universities of Spain, project numbers DPI2017-85359-R (B.B., J.M.) & PID2019-106947RA-C22 (B.B., J.M.) and by Consejería de Economía, Conocimiento, Empresas y Universidad and European Regional Development Fund (ERDF), ref. SOMM17/6109/UGR (J.C., J.M., J.S.). Lastly, B.B. research was granted by Ministry of Science, Innovation and Universities of Spain, FPU2017/01415.
Subjects: Computer science, 01 natural sciences, Forces, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement [Medical Subject Headings], Diffusion, porous media, Qualitative behavior, Computer Science (miscellaneous), Numerical simulations, Homeostasis, Statistical physics, Diffusion (business), Solid tumor, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Mortality::Cause of Death [Medical Subject Headings], Cancer, 0303 health sciences, Partial differential equation, Mathematical modelling, Dynamics (mechanics), Traveling-waves, mathematical modeling, tumor dynamics, Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction [Medical Subject Headings], Diseases::Neoplasms [Medical Subject Headings], flux-saturated, Modelos teóricos, General Mathematics, Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::Porosity [Medical Subject Headings], Context (language use), Information Science::Information Science::Communication::Cybernetics::Feedback [Medical Subject Headings], cell motility, Stress, Mechanics, 03 medical and health sciences, QA1-939, Hele-Shaw model, Movimiento celular, Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::Elasticity [Medical Subject Headings], 0101 mathematics, Engineering (miscellaneous), 030304 developmental biology, Computer simulation, 010102 general mathematics, Porous-media equations, Mass, numerical simulation, Floculadores, Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Transdifferentiation::Epithelial-Mesenchymal Transition [Medical Subject Headings], mechanical feedback, Phenomena and Processes::Physiological Phenomena::Physiological Processes::Homeostasis [Medical Subject Headings], Mathematics
Abstract: What are the biomechanical implications in the dynamics and evolution of a growing solid tumor? Although the analysis of some of the biochemical aspects related to the signaling pathways involved in the spread of tumors has advanced notably in recent times, their feedback with the mechanical aspects is a crucial challenge for a global understanding of the problem. The aim of this paper is to try to illustrate the role and the interaction between some evolutionary processes (growth, pressure, homeostasis, elasticity, or dispersion by flux-saturated and porous media) that lead to collective cell dynamics and defines a propagation front that is in agreement with the experimental data. The treatment of these topics is approached mainly from the point of view of the modeling and the numerical approach of the resulting system of partial differential equations, which can be placed in the context of the Hele-Shaw-type models. This study proves that local growth terms related to homeostatic pressure give rise to retrograde diffusion phenomena, which compete against migration through flux-saturated dispersion terms., MINECO-Feder (Spain) research grant numbers RTI2018-098850-B-I00 (J.C., J.S.) & EQC2018-004508-P (B.B., J.M.), Junta de Andalucía (Spain) Projects PY18-RT-2422 (J.C., J.S.), A-FQM-311-UGR18 (J.C., J.S.) & IE2017-5537 (B.B., J.M.), Instituto de Salud Carlos III, project number DTS17/00087 (J.M., J.S.), Ministry of Science, Innovation and Universities of Spain, project numbers DPI2017-85359-R (B.B., J.M.) & PID2019-106947RA-C22 (B.B., J.M.), Consejería de Economía, Conocimiento, Empresas y Universidad and European Regional Development Fund (ERDF), ref. SOMM17/6109/UGR (J.C., J.M., J.S.), Ministry of Science, Innovation and Universities of Spain, FPU2017/01415
Published: 2021

28. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)

Author: Iurilli, Maria L. C., Zhou, Bin, Bennett, James E., Carrillo-Larco, Rodrigo M., Sophiea, Marisa K., Rodriguez-Martinez, Andrea, Bixby, Honor, Solomon, Bethlehem D., Taddei, Cristina, Danaei, Goodarz, Di Cesare, Mariachiara, Stevens, Gretchen A., Riley, Leanne M., Savin, Stefan, Cowan, Melanie J., Bovet, Pascal, Damasceno, Albertino, Chirita-Emandi, Adela, Hayes, Alison J., Ikeda, Nayu, Jackson, Rod T., Khang, Young-Ho, Laxmaiah, Avula, Liu, Jing, Miranda, J. Jaime, Saidi, Olfa, Sebert, Sylvain, Soric, Maroje, Starc, Gregor, Gregg, Edward W., Abarca-Gomez, Leandra, Abdeen, Ziad A., Abdrakhmanova, Shynar, Ghaffar, Suhaila Abdul, Rahim, Hanan F. Abdul, Abu-Rmeileh, Niveen M., Garba, Jamila Abubakar, Acosta-Cazares, Benjamin, Adams, Robert J., Aekplakorn, Wichai, Afsana, Kaosar, Afzal, Shoaib, Agdeppa, Imelda A., Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A., Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmed, Soheir H., Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M., Al-Lahou, Badreya, Al-Raddadi, Rajaa, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M., Alkandari, Abdullah, Alkerwi, Ala'a, Allin, Kristine, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N., Amiri, Parisa, Amougou, Norbert, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A., Angquist, Lars, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Aounallah-Skhiri, Hajer, Araujo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E., Arlappa, Nimmathota, Aryal, Krishna K., Aspelund, Thor, Assah, Felix K., Assuncao, Maria Cecilia F., Aung, May Soe, Auvinen, Juha, Avdicova, Maria, Avi, Shina, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha, Jorgensen, Maja Boksgaard, Baharudin, Azli, Bahijri, Suhad, Baker, Jennifer L., Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, Jose R., Baran, Joanna, Barbagallo, Carlo M., Barcelo, Alberto, Barkat, Amina, Barros, Aluisio Jd, Gomes Barros, Mauro Virgilio, Basit, Abdul, Bastos, Joao Luiz D., Bata, Iqbal, Batieha, Anwar M., Batista, Rosangela L., Battakova, Zhamilya, Batyrbek, Assembekov, Baur, Louise A., Beaglehole, Robert, Bel-Serrat, Silvia, Belavendra, Antonisamy, Ben Romdhane, Habiba, Benedics, Judith, Benet, Mikhail, Bergh, Ingunn Holden, Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bezerra, Jorge, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K., Bhutta, Zulfiqar A., Bi, Hongsheng, Bi, Yufang, Bia, Daniel, Lele, Elysee Claude Bika, Bikbov, Mukharram M., Bista, Bihungum, Bjelica, Dusko J., Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B., Bjorkelund, Cecilia, Bloch, Katia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boddy, Lynne M., Boehm, Bernhard O., Boeing, Heiner, Boggia, Jose G., Bogova, Elena, Boissonnet, Carlos P., Bojesen, Stig E., Bonaccio, Marialaura, Bongard, Vanina, Bonilla-Vargas, Alice, Bopp, Matthias, Borghs, Herman, Braeckevelt, Lien, Braeckman, Lutgart, Bragt, Marjolijn C. E., Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Breda, Joao, Brenner, Hermann, Brewster, Lizzy M., Brian, Garry R., Brinduse, Lacramioara, Brophy, Sinead, Bruno, Graziella, Bueno-de-Mesquita, H. Bas, Bugge, Anna, Buoncristiano, Marta, Burazeri, Genc, Burns, Con, Cabrera de Leon, Antonio, Cacciottolo, Joseph, Cai, Hui, Cama, Tilema, Cameron, Christine, Camolas, Jose, Can, Gunay, Candido, Ana Paula C., Canete, Felicia, Capanzana, Mario, Capkova, Nadezda, Capuano, Eduardo, Capuano, Vincenzo, Cardol, Marloes, Cardoso, Viviane C., Carlsson, Axel C., Carmuega, Esteban, Carvalho, Joana, Casajus, Jose A., Casanueva, Felipe F., Celikcan, Ertugrul, Censi, Laura, Cervantes-Loaiza, Marvin, Cesar, Juraci A., Chamukuttan, Snehalatha, Chan, Angelique W., Chan, Queenie, Chaturvedi, Himanshu K., Chaturvedi, Nish, Rahim, Norsyamlina Che Abdul, Chee, Miao Li, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Cheraghian, Bahman, Chetrit, Angela, Chikova-Iscener, Ekaterina, Chiolero, Arnaud, Chiou, Shu-Ti, Chirlaque, Maria-Dolores, Cho, Belong, Christensen, Kaare, Christofaro, Diego G. [UNESP], Chudek, Jerzy, Cifkova, Renata, Cilia, Michelle, Cinteza, Eliza, Claessens, Frank, Clarke, Janine, Clays, Els, Cohen, Emmanuel, Concin, Hans, Confortin, Susana C., Cooper, Cyrus, Coppinger, Tara C., Corpeleijn, Eva, Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Craig, Cora L., Crampin, Amelia C., Crujeiras, Ana B., Csilla, Semanova, Cucu, Alexandra M., Cui, Liufu, Cureau, Felipe, Czenczek-Lewandowska, Ewelina, D'Arrigo, Graziella, D'Orsi, Eleonora, Dacica, Liliana, Dal Re Saavedra, Maria Angeles, Dallongeville, Jean, Damsgaard, Camilla T., Dankner, Rachel, Dantoft, Thomas M., Dasgupta, Parasmani, Dastgiri, Saeed, Dauchet, Luc, Davletov, Kairat, De Backer, Guy, De Bacquer, Dirk, Gaetano, Giovanni de, De Henauw, Stefaan, Oliveira, Paula Duarte de, De Ridder, David, De Ridder, Karin, Rooij, Susanne R. de, De Smedt, Delphine, Deepa, Mohan, Deev, Alexander D., DeGennaro, Vincent, Dehghan, Abbas, Delisle, Helene, Delpeuch, Francis, Demarest, Stefaan, Dennison, Elaine, Deren, Katarzyna, Deschamps, Valerie, Dhimal, Meghnath, Di Castelnuovo, Augusto F., Dias-da-Costa, Juvenal Soares, Diaz-Sanchez, Maria Elena, Diaz, Alejandro, Dika, Zivka, Djalalinia, Shirin, Djordjic, Visnja, Do, Ha T. P., Dobson, Annette J., Donati, Maria Benedetta, Donfrancesco, Chiara, Donoso, Silvana P., Doring, Angela, Dorobantu, Maria, Dorosty, Ahmad Reza, Doua, Kouamelan, Dragano, Nico, Drygas, Wojciech, Duan, Jia Li, Duante, Charmaine A., Duboz, Priscilla, Duda, Rosemary B., Duleva, Vesselka, Dulskiene, Virginija, Dumith, Samuel C., Dushpanova, Anar, Dzerve, Vilnis, Dziankowska-Zaborszczyk, Elzbieta, Eddie, Ricky, Eftekhar, Ebrahim, Egbagbe, Eruke E., Eggertsen, Robert, Eghtesad, Sareh, Eiben, Gabriele, Ekelund, Ulf, El-Khateeb, Mohammad, El Ati, Jalila, Eldemire-Shearer, Denise, Eliasen, Marie, Elliott, Paul, Engle-Stone, Reina, Enguerran, Macia, Erasmus, Rajiv T., Erbel, Raimund, Erem, Cihangir, Eriksen, Louise, Eriksson, Johan G., Escobedo-de la Pena, Jorge, Eslami, Saeid, Esmaeili, Ali, Evans, Alun, Faeh, David, Fakhretdinova, Albina A., Fall, Caroline H., Faramarzi, Elnaz, Farjam, Mojtaba, Sant'Angelo, Victoria Farrugia, Farzadfar, Farshad, Fattahi, Mohammad Reza, Fawwad, Asher, Felix-Redondo, Francisco J., Ferguson, Trevor S., Fernandes, Romulo A. [UNESP], Fernandez-Berges, Daniel, Ferrante, Daniel, Ferrao, Thomas, Ferrari, Marika, Ferrario, Marco M., Ferreccio, Catterina, Ferrer, Eldridge, Ferrieres, Jean, Figueiro, Thamara Hubler, Fijalkowska, Anna, Fink, Gunther, Fischer, Krista, Foo, Leng Huat, Forsner, Maria, Fouad, Heba M., Francis, Damian K., Franco, Maria do Carmo, Frikke-Schmidt, Ruth, Frontera, Guillermo, Fuchs, Flavio D., Fuchs, Sandra C., Fujiati, Isti I., Fujita, Yuki, Fumihiko, Matsuda, Furusawa, Takuro, Gaciong, Zbigniew, Gafencu, Mihai, Galbarczyk, Andrzej, Galenkamp, Henrike, Galeone, Daniela, Galfo, Myriam, Galvano, Fabio, Gao, Jingli, Garcia-de-la-Hera, Manoli, Garcia-Solano, Marta, Gareta, Dickman, Garnett, Sarah P., Gaspoz, Jean-Michel, Gasull, Magda, Araujo Gaya, Adroaldo Cesar, Gaya, Anelise Reis, Gazzinelli, Andrea, Gehring, Ulrike, Geiger, Harald, Geleijnse, Johanna M., Ghanbari, Ali, Ghasemi, Erfan, Gheorghe-Fronea, Oana-Florentina, Giampaoli, Simona, Gianfagna, Francesco, Gill, Tiffany K., Giovannelli, Jonathan, Gironella, Glen, Giwercman, Aleksander, Gkiouras, Konstantinos, Godos, Justyna, Gogen, Sibel, Goldberg, Marcel, Goldsmith, Rebecca A., Goltzman, David, Gomez, Santiago F., Gomula, Aleksandra, Cordeiro da Silva, Bruna Goncalves, Goncalves, Helen, Gonzalez-Chica, David A., Gonzalez-Gross, Marcela, Gonzalez-Leon, Margot, Gonzalez-Rivas, Juan P., Gonzalez-Villalpando, Clicerio, Gonzalez-Villalpando, Maria-Elena, Gonzalez, Angel R., Gottrand, Frederic, Graca, Antonio Pedro, Graff-Iversen, Sidsel, Grafnetter, Dusan, Grajda, Aneta, Grammatikopoulou, Maria G., Gregor, Ronald D., Grodzicki, Tomasz, Groholt, Else Karin, Grontved, Anders, Grosso, Giuseppe, Gruden, Gabriella, Gu, Dongfeng, Gualdi-Russo, Emanuela, Guallar-Castillon, Pilar, Gualtieri, Andrea, Gudmundsson, Elias F., Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idris, Guimaraes, Andre L., Gulliford, Martin C., Gunnlaugsdottir, Johanna, Gunter, Marc J., Guo, Xiu-Hua, Guo, Yin, Gupta, Prakash C., Gupta, Rajeev, Gureje, Oye, Gurzkowska, Beata, Gutierrez-Gonzalez, Enrique, Gutierrez, Laura, Gutzwiller, Felix, Ha, Seongjun, Hadaegh, Farzad, Hadjigeorgiou, Charalambos A., Haghshenas, Rosa, Hakimi, Hamid, Halkjaer, Jytte, Hambleton, Ian R., Hamzeh, Behrooz, Hange, Dominique, Hanif, Abu A. M., Hantunen, Sari, Hao, Jie, Kumar, Rachakulla Hari, Hashemi-Shahri, Seyed Mohammad, Hassapidou, Maria, Hata, Jun, Haugsgjerd, Teresa, He, Jiang, He, Yuan, He, Yuna, Heidinger-Felso, Regina, Heinen, Mirjam, Hejgaard, Tatjana, Hendriks, Marleen Elisabeth, Henrique, Rafael dos Santos, Henriques, Ana, Hernandez Cadena, Leticia, Herrala, Sauli, Herrera, Victor M., Herter-Aeberli, Isabelle, Heshmat, Ramin, Hill, Allan G., Ho, Sai Yin, Ho, Suzanne C., Hobbs, Michael, Holdsworth, Michelle, Homayounfar, Reza, Homs, Clara, Hopman, Wilma M., Horimoto, Andrea R. V. R., Hormiga, Claudia M., Horta, Bernardo L., Houti, Leila, Howitt, Christina, Thein Thein Htay, Htet, Aung Soe, Htike, Maung Maung Than, Hu, Yonghua, Huerta, Jose Maria, Huhtaniemi, Ilpo Tapani, Huiart, Laetitia, Petrescu, Constanta Huidumac, Huisman, Martijn, Husseini, Abdullatif, Huu, Chinh Nguyen, Huybrechts, Inge, Hwalla, Nahla, Hyska, Jolanda, Iacoviello, Licia, Ibarluzea, Jesus M., Ibrahim, Mohsen M., Wong, Norazizah Ibrahim, Ikram, M. Arfan, Iotova, Violeta, Irazola, Vilma E., Ishida, Takafumi, Islam, Muhammad, Islam, Sheikh Mohammed Shariful, Iwasaki, Masanori, Jacobs, Jeremy M., Jaddou, Hashem Y., Jafar, Tazeen, James, Kenneth, Jamil, Kazi M., Jamrozik, Konrad, Janszky, Imre, Janus, Edward, Jarani, Juel, Jarvelin, Marjo-Riitta, Jasienska, Grazyna, Jelakovic, Ana, Jelakovic, Bojan, Jennings, Garry, Jha, Anjani Kumar, Jiang, Chao Qiang, Jimenez, Ramon O., Jockel, Karl-Heinz, Joffres, Michel, Johansson, Mattias, Jokelainen, Jari J., Jonas, Jost B., Jonnagaddala, Jitendra, Jorgensen, Torben, Joshi, Pradeep, Joukar, Farahnaz, Jovic, Dragana P., Jozwiak, Jacek J., Juolevi, Anne, Jurak, Gregor, Simina, Iulia Jurca, Juresa, Vesna, Kaaks, Rudolf, Kaducu, Felix O., Kafatos, Anthony, Kajantie, Eero O., Kalmatayeva, Zhanna, Kalter-Leibovici, Ofra, Kameli, Yves, Kampmann, Freja B., Kanala, Kodanda R., Kannan, Srinivasan, Kapantais, Efthymios, Karakosta, Argyro, Karhus, Line L., Karki, Khem B., Katibeh, Marzieh, Katz, Joanne, Katzmarzyk, Peter T., Kauhanen, Jussi, Kaur, Prabhdeep, Kavousi, Maryam, Kazakbaeva, Gyulli M., Keil, Ulrich, Boker, Lital Keinan, Keinanen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kelleher, Cecily, Kemper, Han C. G., Kengne, Andre P., Keramati, Maryam, Kerimkulova, Alina, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khalili, Davood, Khaw, Kay-Tee, Kheiri, Bahareh, Kheradmand, Motahareh, Khosravi, Alireza, Khouw, Ilse M. S. L., Kiechl-Kohlendorfer, Ursula, Kiechl, Stefan, Killewo, Japhet, Kim, Dong Wook, Kim, Hyeon Chang, Kim, Jeongseon, Kindblom, Jenny M., Klakk, Heidi, Klimek, Magdalena, Klimont, Jeannette, Klumbiene, Jurate, Knoflach, Michael, Koirala, Bhawesh, Kolle, Elin, Kolsteren, Patrick, Konig, Jurgen, Korpelainen, Raija, Korrovits, Paul, Korzycka, Magdalena, Kos, Jelena, Koskinen, Seppo, Kouda, Katsuyasu, Kovacs, Viktoria A., Kowlessur, Sudhir, Koziel, Slawomir, Kratenova, Jana, Kratzer, Wolfgang, Kriemler, Susi, Kristensen, Peter Lund, Krokstad, Steiner, Kromhout, Daan, Kruger, Herculina S., Kubinova, Ruzena, Kuciene, Renata, Kujala, Urho M., Kujundzic, Enisa, Kulaga, Zbigniew, Kumar, R. Krishna, Kunesova, Marie, Kurjata, Pawel, Kusuma, Yadlapalli S., Kuulasmaa, Kari, Kyobutungi, Catherine, Quang Ngoc La, Laamiri, Fatima Zahra, Laatikainen, Tiina, Lachat, Carl, Laid, Youcef, Lam, Tai Hing, Lambrinou, Christina-Paulina, Landais, Edwige, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Latt, Tint Swe, Lauria, Laura, Lazo-Porras, Maria, Le Coroller, Gwenaelle, Khanh Le Nguyen Bao, Le Port, Agnes, Le, Tuyen D., Lee, Jeannette, Lee, Jeonghee, Lee, Paul H., Lehmann, Nils, Lehtimaki, Terho, Lemogoum, Daniel, Levitt, Naomi S., Li, Yanping, Liivak, Merike, Lilly, Christa L., Lim, Wei-Yen, Lima-Costa, M. Fernanda, Lin, Hsien-Ho, Lin, Xu, Lin, Yi-Ting, Lind, Lars, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Liu, Lijuan, Lo, Wei-Cheng, Loit, Helle-Mai, Khuong Quynh Long, Lopes, Luis, Lopes, Oscar, Lopez-Garcia, Esther, Lopez, Tania, Lotufo, Paulo A., Eugenio Lozano, Jose, Lukrafka, Janice L., Luksiene, Dalia, Lundqvist, Annamari, Lundqvist, Robert, Lunet, Nuno, Lunogelo, Charles, Lustigova, Michala, Luszczki, Edyta, Ma, Guansheng, Ma, Jun, Ma, Xu, Machado-Coelho, George L. L., Machado-Rodrigues, Aristides M., Macieira, Luisa M., Madar, Ahmed A., Maggi, Stefania, Magliano, Dianna J., Magnacca, Sara, Magriplis, Emmanuella, Mahasampath, Gowri, Maire, Bernard, Majer, Marjeta, Makdisse, Marcia, Maki, Paivi, Malekzadeh, Fatemeh, Malekzadeh, Reza, Malhotra, Rahul, Rao, Kodavanti Mallikharjuna, Malyutina, Sofia K., Maniego, Lynell, Manios, Yannis, Mann, Jim, Mansour-Ghanaei, Fariborz, Manzato, Enzo, Margozzini, Paula, Markaki, Anastasia, Markey, Oonagh, Ioannidou, Eliza Markidou, Marques-Vidal, Pedro, Marques, Larissa Pruner, Marrugat, Jaume, Martin-Prevel, Yves, Martin, Rosemarie, Martorell, Reynaldo, Martos, Eva, Maruszczak, Katharina, Marventano, Stefano, Mascarenhas, Luis P., Masoodi, Shariq R., Mathiesen, Ellisiv B., Mathur, Prashant, Matijasevich, Alicia, Matsha, Tandi E., Mavrogianni, Christina, Mazur, Artur, Mbanya, Jean Claude N., McFarlane, Shelly R., McGarvey, Stephen T., McKee, Martin, McLachlan, Stela, McLean, Rachael M., McLean, Scott B., McNulty, Breige A., Benchekor, Sounnia Mediene, Medzioniene, Jurate, Mehdipour, Parinaz, Mehlig, Kirsten, Mehrparvar, Amir Houshang, Meirhaeghe, Aline, Meisfjord, Jorgen, Meisinger, Christa, Menezes, Ana Maria B., Menon, Geetha R., Mensink, Gert B. M., Menzano, Maria Teresa, Mereke, Alibek, Meshram, Indrapal I., Metspalu, Andres, Meyer, Haakon E., Mi, Jie, Michaelsen, Kim F., Michels, Nathalie, Mikkel, Kairit, Milkowska, Karolina, Miller, Jody C., Minderico, Claudia S., Mini, G. K., Miquel, Juan Francisco, Mirjalili, Mohammad Reza, Mirkopoulou, Daphne, Mirrakhimov, Erkin, Misigoj-Durakovic, Marjeta, Mistretta, Antonio, Mocanu, Veronica, Modesti, Pietro A., Moghaddam, Sahar Saeedi, Mohajer, Bahram, Mohamed, Mostafa K., Mohamed, Shukri F., Mohammad, Kazem, Mohammadi, Zahra, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohan, Viswanathan, Mohanna, Salim, Yusoff, Muhammad Fadhli Mohd, Mohebbi, Iraj, Mohebi, Farnam, Moitry, Marie, Molbo, Drude, Mollehave, Line T., Moller, Niels C., Molnar, Denes, Momenan, Amirabbas, Mondo, Charles K., Monroy-Valle, Michele, Monterrubio-Flores, Eric, Monyeki, Kotsedi Daniel K., Moon, Jin Soo, Moosazadeh, Mahmood, Moreira, Leila B., Morejon, Alain, Moreno, Luis A., Morgan, Karen, Morin, Suzanne N., Mortensen, Erik Lykke, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mota-Pinto, Anabela, Mota, Jorge, Motlagh, Mohammad Esmaeel, Motta, Jorge, Moura-dos-Santos, Marcos Andre, Mridha, Malay K., Msyamboza, Kelias P., Thet Thet Mu, Muc, Magdalena, Mugosa, Boban, Muiesan, Maria L., Mukhtorova, Parvina, Muller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Murtagh, Elaine M., Musa, Kamarul Imran, Milanovic, Sanja Music, Musil, Vera, Mustafa, Norlaila, Nabipour, Iraj, Naderimagham, Shohreh, Nagel, Gabriele, Naidu, Balkish M., Najafi, Farid, Nakamura, Harunobu, Namesna, Jana, Nang, Ei Ei K., Nangia, Vinay B., Nankap, Martin, Narake, Sameer, Nardone, Paola, Nauck, Matthias, Neal, William A., Nejatizadeh, Azim, Nekkantti, Chandini, Nelis, Keiu, Nelis, Liis, Nenko, Ilona, Neovius, Martin, Nervi, Flavio, Nguyen, Chung T., Nguyen, Nguyen D., Quang Ngoc Nguyen, Nieto-Martinez, Ramfis E., Nikitin, Yury P., Ning, Guang, Ninomiya, Toshiharu, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A., Nogueira, Helena, Norat, Teresa, Nordendahl, Maria, Nordestgaard, Borge G., Noto, Davide, Nowak-Szczepanska, Natalia, Al Nsour, Mohannad, Nuhoglu, Irfan, Nurk, Eha, O'Neill, Terence W., O'Reilly, Dermot, Obreja, Galina, Ochimana, Caleb, Ochoa-Aviles, Angelica M., Oda, Eiji, Oh, Kyungwon, Ohara, Kumiko, Ohlsson, Claes, Ohtsuka, Ryutaro, Olafsson, Orn, Olinto, Maria Teresa A., Oliveira, Isabel O., Omar, Mohd Azahadi, Onat, Altan, Ong, Sok King, Ono, Lariane M., Ordunez, Pedro, Ornelas, Rui, Ortiz, Ana P., Ortiz, Pedro J., Osler, Merete, Osmond, Clive, Ostojic, Sergej M., Ostovar, Afshin, Otero, Johanna A., Overvad, Kim, Owusu-Dabo, Ellis, Paccaud, Fred Michel, Padez, Cristina, Pagkalos, Ioannis, Pahomova, Elena, Paiva, Karina Mary de, Pajak, Andrzej, Palli, Domenico, Palloni, Alberto, Palmieri, Luigi, Pan, Wen-Harn, Panda-Jonas, Songhomitra, Pandey, Arvind, Panza, Francesco, Papandreou, Dimitrios, Park, Soon-Woo, Park, Suyeon, Parnell, Winsome R., Parsaeian, Mahboubeh, Pascanu, Ionela M., Pasquet, Patrick, Patel, Nikhil D., Pecin, Ivan, Pednekar, Mangesh S., Peer, Nasheeta, Pei, Gao, Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C., Peres, Marco A., Perez-Farinos, Napoleon, Perez, Cynthia M., Peterkova, Valentina, Peters, Annette, Petersmann, Astrid, Petkeviciene, Janina, Petrauskiene, Ausra, Pettenuzzo, Emanuela, Peykari, Niloofar, Pham, Son Thai, Pichardo, Rafael N., Pierannunzio, Daniela, Pigeot, Iris, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pistelli, Francesco, Pitakaka, Freda, Piwonska, Aleksandra, Pizarro, Andreia N., Plans-Rubio, Pedro, Poh, Bee Koon, Pohlabeln, Hermann, Pop, Raluca M., Popovic, Stevo R., Porta, Miquel, Posch, Georg, Poudyal, Anil, Poulimeneas, Dimitrios, Pouraram, Hamed, Pourfarzi, Farhad, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Price, Alison J., Price, Jacqueline F., Providencia, Rui, Puder, Jardena J., Pudule, Iveta, Puhakka, Soile E., Puiu, Maria, Punab, Margus, Qasrawi, Radwan F., Qorbani, Mostafa, Tran Quoc Bao, Radic, Ivana, Radisauskas, Ricardas, Rahimikazerooni, Salar, Rahman, Mahfuzar, Rahman, Mahmudur, Raitakari, Olli, Raj, Manu, Rakhimova, Ellina, Rakhmatulloev, Sherali, Rakovac, Ivo, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramke, Jacqueline, Ramos, Elisabete, Ramos, Rafel, Rampal, Lekhraj, Rampal, Sanjay, Rarra, Vayia, Rascon-Pacheco, Ramon A., Rasmussen, Mette, Rech, Cassiano Ricardo, Redon, Josep, Reganit, Paul Ferdinand M., Regecova, Valeria, Revilla, Luis, Rezaianzadeh, Abbas, Ribas-Barba, Lourdes, Ribeiro, Robespierre, Riboli, Elio, Richter, Adrian, Rigo, Fernando, Rinaldo, Natascia, Wit, Tobias F. Rinke de, Rito, Ana, Ritti-Dias, Raphael M., Rivera, Juan A., Robitaille, Cynthia, Roccaldo, Romana, Rodrigues, Daniela, Rodriguez-Artalejo, Fernando, Rodriguez-Perez, Maria Del Cristo, Rodriguez-Villamizar, Laura A., Roggenbuck, Ulla, Rojas-Martinez, Rosalba, Rojroongwasinkul, Nipa, Romaguera, Dora, Romeo, Elisabetta L., Rosario, Rafaela, Rosengren, Annika, Rouse, Ian, Roy, Joel G. R., Rubinstein, Adolfo, Ruhli, Frank J., Ruidavets, Jean-Bernard, Sandra Ruiz-Betancourt, Blanca, Ruiz-Castell, Maria, Moreno, Emma Ruiz, Rusakova, Iuliia A., Jonsson, Kenisha Russell, Russo, Paola, Rust, Petra, Rutkowski, Marcin, Sabanayagam, Charumathi, Sacchini, Elena, Sachdev, Harshpal S., Sadjadi, Alireza, Safarpour, Ali Reza, Safiri, Saeid, Saki, Nader, Salanave, Benoit, Salazar Martinez, Eduardo, Salmeron, Diego, Salomaa, Veikko, Salonen, Jukka T., Salvetti, Massimo, Samoutian, Margarita, Sanchez-Abanto, Jose, Sans, Susana, Santa Marina, Loreto, Santos, Diana A., Santos, Ina S., Santos, Lelita C., Santos, Maria Paula, Santos, Osvaldo, Santos, Rute, Sanz, Sara Santos, Saramies, Jouko L., Sardinha, Luis B., Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savvas, Savy, Mathilde, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D., Rosario, Angelika Schaffrath, Schargrodsky, Herman, Schienkiewitz, Anja, Schipf, Sabine, Schmidt, Carsten O., Schmidt, Ida Maria, Schnohr, Peter, Schottker, Ben, Schramm, Sara, Schramm, Stine, Schroder, Helmut, Schultsz, Constance, Schutte, Aletta E., Sein, Aye Aye, Selamat, Rusidah, Sember, Vedrana, Sen, Abhijit, Senbanjo, Idowu O., Sepanlou, Sadaf G., Sequera, Victor, Serra-Majem, Luis, Servais, Jennifer, Sevcikova, Ludmila, Shalnova, Svetlana A., Shamah-Levy, Teresa, Shamshirgaran, Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K., Shaw, Jonathan E., Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shengelia, Lela, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shin, Dong Wook, Shirani, Majid, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M., Silva, Antonio M., Silva, Diego Augusto Santos, Simon, Mary, Simons, Judith, Simons, Leon A., Sjoberg, Agneta, Sjostrom, Michael, Skodje, Gry, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobek, Grzegorz, Sobngwi, Eugene, Sodemann, Morten, Soderberg, Stefan, Soekatri, Moesijanti Y. E., Soemantri, Agustinus, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Sorensen, Thorkild I. A., Sorgjerd, Elin P., Jerome, Charles Sossa, Soto-Rojas, Victoria E., Soumare, Aicha, Sovic, Slavica, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Spinelli, Angela, Spiroski, Igor, Staessen, Jan A., Stamm, Hanspeter, Stathopoulou, Maria G., Staub, Kaspar, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D., Stergiou, George S., Stessman, Jochanan, Stevanovic, Ranko, Stieber, Jutta, Stockl, Doris, Stocks, Tanja, Stokwiszewski, Jakub, Stoyanova, Ekaterina, Stratton, Gareth, Stronks, Karien, Federal, Maria Wany Strufaldi, Sturua, Lela, Suarez-Medina, Ramon, Suka, Machi, Sun, Chien-An, Sundstrom, Johan, Sung, Yn-Tz, Sunyer, Jordi, Suriyawongpaisal, Paibul, Swinburn, Boyd A., Sy, Rody G., Syddall, Holly E., Sylva, Rene Charles, Szklo, Moyses, Szponar, Lucjan, Tai, E. Shyong, Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanrygulyyeva, Maya, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B., Braunerova, Radka Taxova, Taylor, Anne, Taylor, Julie, Tchibindat, Felicite, Tebar, William R. [UNESP], Tell, Grethe S., Tello, Tania, Tham, Yih Chung, Thankappan, K. R., Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thomas, Nihal, Thuesen, Betina H., Ticha, Lubica, Timmermans, Erik J., Tjonneland, Anne, Tolonen, Hanna K., Tolstrup, Janne S., Topbas, Murat, Topor-Madry, Roman, Torheim, Liv Elin, Tormo, Maria Jose, Tornaritis, Michael J., Torrent, Maties, Torres-Collado, Laura, Toselli, Stefania, Touloumi, Giota, Traissac, Pierre, Thi Tuyet-Hanh Tran, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Oanh Th Trinh, Trivedi, Atul, Tshepo, Lechaba, Tsigga, Maria, Tsugane, Shoichiro, Tuliakova, Azaliia M., Tulloch-Reid, Marshall K., Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L., Twig, Gilad, Tynelius, Per, Tzotzas, Themistoklis, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ukoli, Flora Am, Ulmer, Hanno, Unal, Belgin, Usupova, Zhamyila, Uusitalo, Hannu M. T., Uysal, Nalan, Vaitkeviciute, Justina, Valdivia, Gonzalo, Vale, Susana, Valvi, Damaskini, van Dam, Rob M., Van der Heyden, Johan, van der Schouw, Yvonne T., Van Herck, Koen, Van Minh, Hoang, Van Schoor, Natasja M., van Valkengoed, Irene G. M., Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Varela-Moreiras, Gregorio, Varona-Perez, Patricia, Vasan, Senthil K., Vega, Tomas, Veidebaum, Toomas, Velasquez-Melendez, Gustavo, Velika, Biruta, Veronesi, Giovanni, Verschuren, W. M. Monique, Victora, Cesar G., Viegi, Giovanni, Viet, Lucie, Villalpando, Salvador, Vineis, Paolo, Vioque, Jesus, Virtanen, Jyrki K., Visser, Marjolein, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vladulescu, Mihaela, Vlasoff, Tiina, Vocanec, Dorja, Vollenweider, Peter, Volzke, Henry, Voutilainen, Ari, Voutilainen, Sari, Vrijheid, Martine, Vrijkotte, Tanja G. M., Wade, Alisha N., Wagner, Aline, Medical, Thomas Waldhor, Walton, Janette, Wambiya, Elvis O. A., Bebakar, Wan Mohamad Wan, Mohamud, Wan Nazaimoon Wan, Junior, Rildo de Souza Wanderley, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S. Goya, Wareham, Nicholas, Weber, Adelheid, Wedderkopp, Niels, Weerasekera, Deepa, Weghuber, Daniel, Wei, Wenbin, Weres, Aneta, Werner, Bo, Whincup, Peter H., Medical, Kurt Widhalm, Widyahening, Indah S., Wiecek, Andrzej, Wilks, Rainford J., Willeit, Johann, Willeit, Peter, Williams, Julianne, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A., Wong, Andrew, Wong, Jyh Eiin, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Frederick C., Wu, Jianfeng, Wu, Li Juan, Wu, Shouling, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yamborisut, Uruwan, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yardim, Nazan, Yaseri, Mehdi, Yasuharu, Tabara, Ye, Xingwang, Yiallouros, Panayiotis K., Yoosefi, Moein, Yoshihara, Akihiro, You, Qi Sheng, You, San-Lin, Younger-Coleman, Novie O., Yusof, Safiah Md, Yusoff, Ahmad Faudzi, Zaccagni, Luciana, Zafiropulos, Vassilis, Zainuddin, Ahmad A., Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antonis, Zamrazilova, Hana, Zapata, Maria Elisa, Zargar, Abdul Hamid, Zaw, Ko Ko, Zdrojewski, Tomasz, Zejglicova, Kristyna, Vrkic, Tajana Zeljkovic, Zeng, Yi, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhao, Wenhua, Zhen, Shiqi, Zheng, Wei, Zheng, Yingfeng, Zholdin, Bekbolat, Zhou, Maigeng, Zhu, Dan, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Cisneros, Julio Zuniga, Zuziak, Monika, Ezzati, Majid, Filippi, Sarah, NCD Risk Factor Collaboration NCD, Imperial Coll London, Harvard TH Chan Sch Publ Hlth, Middlesex Univ, World Hlth Org, Minist Hlth, Univ Lausanne, Eduardo Mondlane Univ, Victor Babes Univ Med & Pharm Timisoara, Univ Sydney, Natl Inst Biomed Innovat Hlth & Nutr, Univ Auckland, Seoul Natl Univ, ICMR Natl Inst Nutr, Capital Med Univ, Univ Peruana Cayetano Heredia, Univ Tunis El Manar, Univ Oulu, Univ Zagreb, Univ Ljubljana, Caja Costarricense Seguro Social, Al Quds Univ, Natl Ctr Publ Healthcare, Qatar Univ, Birzeit Univ, Usmanu Danfodiyo Univ Teaching Hosp, Inst Mexicano Seguro Social, Flinders Univ S Australia, Mahidol Univ, BRAC James P Grant Sch Publ Hlth, Univ Copenhagen, Copenhagen Univ Hosp, Food & Nutr Res Inst, Urmia Univ Med Sci, Inst Nacl Ciencias Med & Nut, Univ Amsterdam, Shahrekord Univ Med Sci, Noncommunicable Dis Res Ctr, Univ Oslo, Univ Bremen, Republican Ctr Hlth Promot, Natl Ctr Diabet Endocrinol & Genet, Princess Nourah Bint Abdulrahman Univ, Kuwait Inst Sci Res, King Abdulaziz Univ, Dasman Diabet Inst, Luxembourg Inst Hlth, Aldara Hosp & Med Ctr, King Abdullah Int Med Res Ctr, Bispebjerg & Frederiksberg Hosp, Barcelona Inst Global Hlth CIBERESP, World Hlth Org Reg Off Eastern Mediterranean, Bombay Hosp & Med Res Ctr, Res Ctr Social Determinants Hlth, UMR CNRS MNHN 7206 Ecoanthropologie, Univ Lille, Lille Univ Hosp, Western Norway Univ Appl Sci, Norwegian Sch Sport Sci, Madras Diabet Res Fdn, Zahedan Univ Med Sci, Natl Inst Publ Hlth, Univ Porto, Norwegian Inst Publ Hlth, Univ Massachusetts, Abt Associates Inc, Univ Iceland, Univ Yaounde I, Univ Fed Pelotas, Univ Med 1, Banska Bystrica Reg Author Publ Hlth, Tel Aviv Univ, Hebrew Univ Jerusalem, Neyshabur Univ Med Sci, Res Inst Endocrine Sci, Indian Council Med Res, Univ Sci & Technol, Med Univ Lodz, Med Univ Gdansk, Univ Autonoma Madrid CIBERESP, Univ Rzeszow, Univ Palermo, Pan Amer Hlth Org, Mohammed V Univ Rabat, Univ Pernambuco, Baqai Inst Diabetol & Endocrinol, Universidade Federal de Santa Catarina (UFSC), Dalhousie Univ, Jordan Univ Sci & Technol, Univ Fed Maranhao, Farabi Kazakh Natl Univ, Univ Coll Dublin, Christian Med Coll & Hosp, Fed Minist Social Affairs Hlth Care & Consumer Pr, Cafam Univ Fdn, Kazakh Natl Med Univ, Lithuanian Univ Hlth Sci, Universidade de São Paulo (USP), BJ Med Coll, Chirayu Med Coll, Sunder Lal Jain Hosp, Hosp Sick Children, Shandong Univ Tradit Chinese Med, Shanghai Jiao Tong Univ, Univ Republica, Inst Med Res & Med Plant Studies, Ufa Eye Res Inst, Nepal Hlth Res Council, Univ Montenegro, Univ Southern Denmark, Univ Gothenburg, Universidade Federal do Rio de Janeiro (UFRJ), Natl Inst Publ Hlth & Environm, Univ Turin, UCL, Liverpool John Moores Univ, Nanyang Technol Univ Singapore, German Inst Human Nutr, Endocrinol Res Ctr, Ctr Educ Med & Invest Clin, IRCCS Neuromed, Toulouse Univ, Univ Zurich, Univ Hosp KU Leuven, Flemish Agcy Care & Hlth, Univ Ghent, FrieslandCampina, Univ Cent Venezuela, Bielefeld Univ, World Hlth Org Reg Off Europe, German Canc Res Ctr, Fred Hollows Fdn, Univ Med & Pharm Bucharest, Swansea Univ, Univ Coll Copenhagen, Inst Publ Hlth, Munster Technol Univ, Univ La Laguna, Univ Malta, Vanderbilt Univ, Canadian Fitness & Lifestyle Res Inst, Hosp Santa Maria, Istanbul Univ Cerrahpasa, Univ Fed Juiz de Fora, Minist Publ Hlth, Gaetano Fucito Hosp, Univ Groningen, Karolinska Inst, Ctr Estudios Nutr Infantil, Univ Zaragoza, Santiago de Compostela Univ, Council Agr Res & Econ, Fed Univ Rio Grande, India Diabet Res Fdn, Duke NUS Med Sch, ICMR Natl Inst Med Stat, Singapore Eye Res Inst, Acad Sinica, Capital Inst Pediat, Duke Univ, Kailuan Gen Hosp, Univ Oxford, Ahvaz Jundishapur Univ Med Sci, Gertner Inst Epidemiol & Hlth Policy Res, Natl Ctr Publ Hlth & Anal, Univ Fribourg, Minist Hlth & Welf, CIBER Epidemiol & Salud Publ, Universidade Estadual Paulista (Unesp), Med Univ Silesia, Charles Univ Prague, Primary Hlth Care, Carol Davila Univ Med & Pharm, Katholieke Univ Leuven, STAT Canada, UMR CNRS MNHN 7206 Ecoanthropol, Agcy Prevent & Social Med, Univ Southampton, Inst Pasteur, Malawi Epidemiol & Intervent Res Unit, CIBEROBN, Univ Debrecen, Univ Med & Pharm Carol Davila, Univ Fed Rio Grande do Sul, CNR, Eftimie Murgu Univ Resita, Spanish Agcy Food Safety & Nutr, Indian Stat Inst, Tabriz Hlth Serv Management Res Ctr, Geneva Univ Hosp, Sciensano, Univ Med Ctr Groningen, Natl Res Ctr Prevent Med, Innovating Hlth Int, Univ Montreal, French Natl Res Inst Sustainable Dev, French Publ Hlth Agcy, Mediterranea Cardioctr, Univ Vale Rio dos Sinos, Natl Inst Hyg Epidemiol & Microbiol, Natl Council Sci & Tech Res, Minist Hlth & Med Educ, Univ Novi Sad, Natl Inst Nutr, Univ Queensland, Ist Super Sanita, Univ Cuenca, Helmholtz Zentrum Munchen, Univ Tehran Med Sci, Minist Sante & Hyg Publ, Univ Hosp Dusseldorf, Natl Inst Cardiol, Beijing Ctr Dis Prevent & Control, UMI 3189 ESS, Beth Israel Deaconess Med Ctr, Scuola Super Sant Anna, Univ Latvia, Minist Hlth & Med Serv, Hormozgan Univ Med Sci, Univ Benin, Univ Skovde, Natl Inst Nutr & Food Technol, Univ West Indies, Univ Calif Davis, Univ Stellenbosch, Univ Duisburg Essen, Karadeniz Tech Univ, Univ Helsinki, Mashhad Univ Med Sci, Rafsanjan Univ Med Sci, Queens Univ Belfast, Tabriz Univ Med Sci, Fasa Univ Med Sci, Shiraz Univ Med Sci, Baqai Med Univ, Ctr Salud Villanueva Norte, Hosp Don Benito Villanueva Serena, Univ Insubria, Pontificia Univ Catolica Chile, Inst Mother & Child Hlth, Swiss Trop & Publ Hlth Inst, Univ Tartu, Univ Sains Malaysia, Umea Univ, Universidade Federal de São Paulo (UNIFESP), Hosp Univ Son Espases, Hosp Clin Porto Alegre, Univ Sumatera Utara, Kindai Univ, Kyoto Univ, Med Univ Warsaw, Jagiellonian Univ, Minist Salute DG Prevenz Sanit, Univ Catania, Africa Hlth Res Inst, Univ Geneva, Universidade Federal de Minas Gerais (UFMG), Univ Utrecht, Wageningen Univ, Univ Adelaide, Lund Univ, Aristotle Univ Thessaloniki, Inst Natl Sante & Rech Med, McGill Univ, Gasol Fdn, PASs Hirszfeld Inst Immunol & Expt Therapy, Univ Politecn Madrid, St Annes Univ Hosp, Ctr Estudios Diabet AC, Univ Autonoma Santo Domingo, Inst Clin & Expt Med, Childrens Mem Hlth Inst, Natl Ctr Cardiovasc Dis, Univ Ferrara, Author Sanitaria San Marino, Iceland Heart Assoc, Univ Icesi, Univ Estadual Montes Claros, Kings Coll London, Int Agcy Res Canc, Healis Sekhsaria Inst Publ Hlth, Eternal Heart Care Ctr & Res Inst, Univ Ibadan, Inst Clin Effectiveness & Hlth Policy, Natl Hlth Insurance Serv, Prevent Metab Disorders Res Ctr, Res & Educ Inst Child Hlth, Danish Canc Soc Res Ctr, Kermanshah Univ Med Sci, Univ Eastern Finland, Beijing Inst Ophthalmol, Int Hellen Univ, Kyushu Univ, Univ Bergen, Tulane Univ, Natl Res Inst Hlth & Family Planning, Chinese Ctr Dis Control & Prevent, Univ Pecs, Danish Hlth Author, Joep Lange Inst, Universidade Federal de Pernambuco (UFPE), Oulu Univ Hosp, Univ Autonoma Bucaramanga, Swiss Fed Inst Technol, Chron Dis Res Ctr, Univ Hong Kong, Chinese Univ Hong Kong, Univ Western Australia, Kingston Hlth Sci Ctr, Fdn Oftalmol Santander, Univ Oran 1, Nay Pyi Taw, Minist Hlth & Sports, Peking Univ, Vrije Univ Amsterdam Med Ctr, Amer Univ Beirut, Cairo Univ, Erasmus MC, Med Univ Varna, Univ Tokyo, Deakin Univ, Tokyo Metropolitan Inst Gerontol, Hadassah Univ Med Ctr, Norwegian Univ Sci & Technol, Univ Melbourne, Sports Univ Tirana, Univ Hosp Ctr Zagreb, Heart Fdn, Guangzhou 12th Hosp, Univ Eugenio Maria Hostos, Simon Fraser Univ, Inst Mol & Clin Ophthalmol Basel, Univ New South Wales, World Hlth Org Country Off, Guilan Univ Med Sci, Univ Opole, Finnish Inst Hlth & Welf, Gulu Univ, Univ Crete, Sri Venkateswara Univ, Sree Chitra Tirunal Inst Med Sci & Technol, Hellen Med Assoc Obes, Natl & Kapodistrian Univ Athens, Aarhus Univ, Johns Hopkins Bloomberg Sch Publ Hlth, Pennington Biomed Res Ctr, Natl Inst Epidemiol, Univ Munster, Israel Ctr Dis Control, Res Inst Primordial Prevent Noncommunicable Dis, Amsterdam UMC Publ Hlth Res Inst, South African Med Res Council, Kyrgyz State Med Acad, Res Inst Child Nutr, Shahid Beheshti Univ Med Sci, Univ Cambridge, Mazandaran Univ Med Sci, Hypertens Res Ctr, Med Univ Innsbruck, Muhimbili Univ Hlth & Allied Sci, Yonsei Univ, Natl Canc Ctr, Univ Coll South Denmark, Stat Austria, BP Koirala Inst Hlth Sci, Univ Vienna, Tartu Univ Clin, Kansai Med Univ, Hungarian Sch Sport Federat, Minist Hlth & Qual Life, Univ Hosp Ulm, North West Univ, Univ Jyvaskyla, Amrita Inst Med Sci, Inst Endocrinol, All India Inst Med Sci, African Populat & Hlth Res Ctr, Hanoi Univ Publ Hlth, Hassan First Univ Settat, Harokopio Univ, Sahlgrens Acad, Endocrinol & Metab Res Ctr, Univ Publ Hlth, Int Food Policy Res Inst, Natl Univ Singapore, Hong Kong Polytech Univ, Tampere Univ Hosp, Univ Douala, Univ Cape Town, Natl Inst Hlth Dev, West Virginia Univ, Oswaldo Cruz Fdn Rene Rachou Res Inst, Natl Taiwan Univ, Univ Chinese Acad Sci, Uppsala Univ, Taipei Med Univ, Sports Med Ctr Minho, Univ San Martin Porres, Consejeria Sanidad Junta Castilla & Leon, Univ Fed Ciencias Saude Porto Alegre, Norrbotten Cty Council, Ilembula Lutheran Hosp, Univ Fed Ouro Preto, Univ Coimbra, Coimbra Univ Hosp Ctr, Inst Neurosci Natl Res Council, Baker Heart & Diabet Inst, Agr Univ Athens, Hosp Israelita Albert Einstein, SB RAS Fed Res Ctr Inst Cytol & Genet, Univ Otago, Univ Padua, Hellen Mediterranean Univ, Loughborough Univ, Lausanne Univ Hosp, Escola Nacl Saude Publ Sergio Arouca, CIBERCV, Mary Immaculate Coll, Emory Univ, Hungarian Soc Sports Med, Paracelsus Med Univ, Univ Estadual Centro Oeste, Sherikashmir Inst Med Sci, UiT Arctic Univ Norway, ICMR Natl Ctr Dis Informat & Res, Cape Peninsula Univ Technol, Brown Univ, London Sch Hyg & Trop Med, Univ Edinburgh, Shahid Sadoughi Univ Med Sci, Robert Koch Inst, Univ Lisbon, Womens Social & Hlth Studies Fdn, Democritus Univ, Grigore T Popa Univ Med & Pharm, Univ Firenze, Ain Shams Univ, Isfahan Cardiovasc Res Ctr, Univ Strasbourg, Mulago Hosp, Univ San Carlos, Univ Limpopo, Univ Med Sci Cienfuegos, Royal Coll Surgeons Ireland, Trobe Univ, Int Inst Mol & Cell Biol, Inst Conmemorat Gorgas Estudios Salud, Dept Publ Hlth, Univ Brescia, Minist Hlth & Social Protect, Univ Limerick, Croatian Inst Publ Hlth, Univ Kebangsaan Malaysia, Bushehr Univ Med Sci, Ulm Univ, Dept Stat, Kobe Univ, Suraj Eye Inst, UNICEF, Univ Med Greifswald, Natl Inst Hyg & Epidemiol, Univ Med & Pharm Ho Chi Minh City, Hanoi Med Univ, LifeDoc Hlth, Heartfile, Eastern Mediterranean Publ Hlth Network, Univ Manchester, State Univ Med & Pharm, Tachikawa Gen Hosp, Korea Ctr Dis Control & Prevent, Japan Wildlife Res Ctr, Istanbul Univ, Univ Fed Parana, Univ Madeira, Univ Puerto Rico, Ctr Clin Res & Prevent, MRC Lifecourse Epidemiol Unit, Kwame Nkrumah Univ Sci & Technol, UniSante, Inst Canc Res, Univ Wisconsin, Heidelberg Univ, IRCCS Ente Osped Specializzato Gastroenterol S de, Zayed Univ, Catholic Univ Daegu, Univ Med Pharm Sci & Technol Targu Mures, Jivandeep Hosp, Natl Dent Care Ctr Singapore, Univ Malaga, Univ Hosp Varese, Vietnam Natl Heart Inst, Clin Med Avanzada Dr Abel Gonzalez, Leibniz Inst Prevent Res & Epidemiol BIPS, Univ Sarajevo, Cardiovasc Prevent Ctr Udine, Pisa Univ Hosp, Publ Hlth Agcy Catalonia, Inst Hosp del Mar Invest Med, Ardabil Univ Med Sci, Ctr Dis Prevent & Control, Alborz Univ Med Sci, Pure Earth, Inst Epidemiol Dis Control & Res, Univ Turku, Inst Univ Invest Atenc Primaria Jordi Gol, Univ Putra Malaysia, Univ Malaya, Sotiria Hosp, Univ Valencia, Univ Philippines, Slovak Acad Sci, Nutr Res Fdn, Minas Gerais State Secretariat Hlth, CS S Agustin Ibsalut, Amsterdam Inst Global Hlth & Dev, Natl Inst Hlth Doutor Ricardo Jorge, Univ Nove Julho, Publ Hlth Agcy Canada, Canarian Hlth Serv, Univ Ind Santander, Assoc Calabrese Epatol, Univ Minho, Fiji Natl Univ, Spanish Nutr Fdn, Publ Hlth Agcy Sweden, Inst Food Sci Natl Res Council, Sitaram Bhartia Inst Sci & Res, Kindergarten Avlonari, Natl Inst Hlth, Catalan Dept Hlth, Biodonostia Hlth Res Inst, Inst Saude Ambiental, South Karelia Social & Hlth Care Dist, McMaster Univ, Hosp Italiano Buenos Aires, Rigshosp, Acad Med Ctr Univ Amsterdam, Ctr Oral Hlth Serv & Res Midnorway, Lagos State Univ, Univ Las Palmas Gran Canaria, Comenius Univ, Natl Ctr Dis Control & Publ Hlth, Nippon Med Sch, Sungkyunkwan Univ, Finnish Inst Occupat Hlth, Publ Hlth Promot & Dev Org, St Vincents Hosp, Nes Municipal, Hlth Polytech Jakarta II Inst, Diponegoro Univ, Univ Bari, Inst Reg Sante Publ, Univ Bordeaux, Oslo Metropolitan Univ, Univ Leuven, Lamprecht & Stamm Sozialforsch & Beratung AG, Univ Bonn, Kalina Malina Kindergarten, Jikei Univ, Fu Jen Catholic Univ, Natl Stat Off, Natl Inst Publ Hlth Natl Inst Hyg, Sci Res Inst Maternal & Child Hlth, Univ Lincoln, Cent Univ Kerala, Amsterdam Publ Hlth Res Inst, Hlth Serv Murcia, Inst Invest Sanitaria Illes Balears, Univ Bologna, Hellen Hlth Fdn, Govt Med Coll, Sefako Makgatho Hlth Sci Univ, Addis Ababa Univ, Univ Ctr Occidental Lisandro Alvarado, Meharry Med Coll, Dokuz Eylul Univ, Univ Tampere, Sabiha Gokcen Ilkokulu, Polytech Inst Porto, Icahn Sch Med Mt Sinai, Univ CEU San Pablo, Univ Miguel Hernandez, Vrije Univ Amsterdam, Sunflower Nursery Sch, North Karelia Ctr Publ Hlth, Univ Witwatersrand, Med Univ Vienna, Cork Inst Technol, Inst Med Res, Xinjiang Med Univ, Shanghai Educ Dev Co Ltd, Rebro Univ, St Georges Univ London, Univ Indonesia, Minist Agr & Rural Affairs, Fudan Univ, Univ Cyprus, Niigata Univ, Int Med Univ, Iran Univ Med Sci, Ctr Diabet & Endocrine Care, Peking Univ First Hosp, Jiangsu Prov Ctr Dis Control & Prevent, Sun Yat Sen Univ, West Kazakhstan Med Univ, Inner Mongolia Med Univ, and Przedszkole 81
Subjects: Life Sciences & Biomedicine - Other Topics, Science & Technology, AUSTRALIAN ADULTS, CHINESE ADULTS, nutritional and metabolic diseases, MALNUTRITION, TRENDS, DOUBLE BURDEN, PREVALENCE, POOLED ANALYSIS, US ADULTS, SYSTEMATIC ANALYSIS, HEALTH, sense organs, skin and connective tissue diseases, Life Sciences & Biomedicine, Biology
Abstract: Made available in DSpace on 2021-06-25T15:08:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-09 Wellcome Trust From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions. Imperial Coll London, London, England Harvard TH Chan Sch Publ Hlth, Boston, MA USA Middlesex Univ, London, England World Hlth Org, Geneva, Switzerland Minist Hlth, Victoria, Seychelles Univ Lausanne, Lausanne, Switzerland Eduardo Mondlane Univ, Maputo, Mozambique Victor Babes Univ Med & Pharm Timisoara, Timisoara, Romania Univ Sydney, Sydney, NSW, Australia Natl Inst Biomed Innovat Hlth & Nutr, Tokyo, Japan Univ Auckland, Auckland, New Zealand Seoul Natl Univ, Seoul, South Korea ICMR Natl Inst Nutr, Hyderabad, India Capital Med Univ, Beijing An Zhen Hosp, Beijing, Peoples R China Univ Peruana Cayetano Heredia, Lima, Peru Univ Tunis El Manar, Tunis, Tunisia Univ Oulu, Oulu, Finland Univ Zagreb, Zagreb, Croatia Univ Ljubljana, Ljubljana, Slovenia Caja Costarricense Seguro Social, San Jose, Costa Rica Al Quds Univ, East Jerusalem, State Of Palest, Palestine Natl Ctr Publ Healthcare, Nur Sultan, Kazakhstan Minist Hlth, Kuala Lumpur, Malaysia Qatar Univ, Doha, Qatar Birzeit Univ, Birzeit, State Of Palest, Israel Usmanu Danfodiyo Univ Teaching Hosp, Sokoto, Nigeria Inst Mexicano Seguro Social, Mexico City, DF, Mexico Flinders Univ S Australia, Adelaide, SA, Australia Mahidol Univ, Salaya, Nakhon Pathom, Thailand BRAC James P Grant Sch Publ Hlth, Dhaka, Bangladesh Univ Copenhagen, Copenhagen, Denmark Copenhagen Univ Hosp, Copenhagen, Denmark Food & Nutr Res Inst, Taguig, Philippines Urmia Univ Med Sci, Orumiyeh, Iran Inst Nacl Ciencias Med & Nut, Mexico City, DF, Mexico Univ Amsterdam, Amsterdam, Netherlands Shahrekord Univ Med Sci, Shahrekord, Iran Noncommunicable Dis Res Ctr, Tehran, Iran Univ Oslo, Oslo, Norway Univ Bremen, Bremen, Germany Republican Ctr Hlth Promot, Bishkek, Kyrgyzstan Natl Ctr Diabet Endocrinol & Genet, Amman, Jordan Princess Nourah Bint Abdulrahman Univ, Riyadh, Saudi Arabia Kuwait Inst Sci Res, Kuwait, Kuwait King Abdulaziz Univ, Jeddah, Saudi Arabia Dasman Diabet Inst, Kuwait, Kuwait Luxembourg Inst Hlth, Strassen, Luxembourg Aldara Hosp & Med Ctr, Riyadh, Saudi Arabia King Abdullah Int Med Res Ctr, Riyadh, Saudi Arabia Bispebjerg & Frederiksberg Hosp, Copenhagen, Denmark Barcelona Inst Global Hlth CIBERESP, Barcelona, Spain World Hlth Org Reg Off Eastern Mediterranean, Cairo, Egypt Bombay Hosp & Med Res Ctr, Mumbai, Maharashtra, India Res Ctr Social Determinants Hlth, Tehran, Iran UMR CNRS MNHN 7206 Ecoanthropologie, Paris, France Univ Lille, Lille, France Lille Univ Hosp, Lille, France Western Norway Univ Appl Sci, Sogndal, Norway Norwegian Sch Sport Sci, Oslo, Norway Madras Diabet Res Fdn, Chennai, Tamil Nadu, India Zahedan Univ Med Sci, Zahedan, Iran Natl Inst Publ Hlth, Tunis, Tunisia Univ Porto, Inst Publ Hlth, Porto, Portugal Norwegian Inst Publ Hlth, Oslo, Norway Univ Massachusetts, Amherst, MA 01003 USA Abt Associates Inc, Kathmandu, Nepal Univ Iceland, Reykjavik, Iceland Univ Yaounde I, Yaounde, Cameroon Univ Fed Pelotas, Pelotas, RS, Brazil Univ Med 1, Yangon, Myanmar Banska Bystrica Reg Author Publ Hlth, Banska Bystrica, Slovakia Tel Aviv Univ, Tel Aviv, Israel Hebrew Univ Jerusalem, Jerusalem, Israel Univ Porto, Med Sch, Porto, Portugal Neyshabur Univ Med Sci, Neyshabur, Iran Res Inst Endocrine Sci, Tehran, Iran Indian Council Med Res, New Delhi, India Natl Inst Publ Hlth, Copenhagen, Denmark Univ Sci & Technol, Sanaa, Yemen Med Univ Lodz, Lodz, Poland Med Univ Gdansk, Gdansk, Poland Univ Autonoma Madrid CIBERESP, Madrid, Spain Univ Rzeszow, Rzeszow, Poland Univ Palermo, Palermo, Italy Pan Amer Hlth Org, Washington, DC USA Mohammed V Univ Rabat, Rabat, Morocco Univ Pernambuco, Recife, PE, Brazil Baqai Inst Diabetol & Endocrinol, Karachi, Pakistan Univ Fed Santa Catarina, Florianopolis, SC, Brazil Dalhousie Univ, Halifax, NS, Canada Jordan Univ Sci & Technol, Irbid, Jordan Univ Fed Maranhao, Sao Luis, Brazil Farabi Kazakh Natl Univ, Alma Ata, Kazakhstan Univ Coll Dublin, Dublin, Ireland Christian Med Coll & Hosp, Vellore, Tamil Nadu, India Fed Minist Social Affairs Hlth Care & Consumer Pr, Vienna, Austria Cafam Univ Fdn, Bogota, Colombia Kazakh Natl Med Univ, Alma Ata, Kazakhstan Lithuanian Univ Hlth Sci, Kaunas, Lithuania Univ Sao Paulo, Sao Paulo, Brazil BJ Med Coll, Ahmadabad, Gujarat, India Chirayu Med Coll, New Delhi, India Sunder Lal Jain Hosp, Delhi, India Hosp Sick Children, Toronto, ON, Canada Shandong Univ Tradit Chinese Med, Jinan, Peoples R China Shanghai Jiao Tong Univ, Sch Med, Shanghai, Peoples R China Univ Republica, Montevideo, Uruguay Inst Med Res & Med Plant Studies, Yaounde, Cameroon Ufa Eye Res Inst, Ufa, Russia Nepal Hlth Res Council, Kathmandu, Nepal Univ Montenegro, Niksic, Montenegro Univ Southern Denmark, Copenhagen, Denmark Univ Gothenburg, Gothenburg, Sweden Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil Natl Inst Publ Hlth & Environm, Bilthoven, Netherlands Univ Turin, Turin, Italy UCL, London, England Liverpool John Moores Univ, Liverpool, Merseyside, England Nanyang Technol Univ Singapore, Singapore, Singapore German Inst Human Nutr, Potsdam, Germany Endocrinol Res Ctr, Moscow, Russia Ctr Educ Med & Invest Clin, Buenos Aires, DF, Argentina IRCCS Neuromed, Pozzilli, Italy Toulouse Univ, Sch Med, Toulouse, France Univ Zurich, Zurich, Switzerland Univ Hosp KU Leuven, Leuven, Belgium Flemish Agcy Care & Hlth, Brussels, Belgium Univ Ghent, Ghent, Belgium FrieslandCampina, Amersfoort, Netherlands Univ Cent Venezuela, Caracas, Venezuela Bielefeld Univ, Bielefeld, Germany World Hlth Org Reg Off Europe, Moscow, Russia German Canc Res Ctr, Heidelberg, Germany Fred Hollows Fdn, Auckland, New Zealand Univ Med & Pharm Bucharest, Bucharest, Romania Swansea Univ, Swansea, W Glam, Wales Univ Coll Copenhagen, Copenhagen, Denmark Inst Publ Hlth, Tirana, Albania Munster Technol Univ, Cork, Ireland Univ La Laguna, Tenerife, Spain Univ Malta, Msida, Malta Vanderbilt Univ, 221 Kirkland Hall, Nashville, TN 37235 USA Minist Hlth, Tongatapu, Tonga Canadian Fitness & Lifestyle Res Inst, Ottawa, ON, Canada Hosp Santa Maria, Lisbon, Portugal Istanbul Univ Cerrahpasa, Istanbul, Turkey Univ Fed Juiz de Fora, Juiz De Fora, Brazil Minist Publ Hlth, Asuncion, Paraguay Natl Inst Publ Hlth, Prague, Czech Republic Gaetano Fucito Hosp, Mercato San Severino, Italy Univ Groningen, Groningen, Netherlands Karolinska Inst, Huddinge, Sweden Ctr Estudios Nutr Infantil, Buenos Aires, DF, Argentina Univ Porto, Porto, Portugal Univ Zaragoza, Zaragoza, Spain Santiago de Compostela Univ, Santiago De Compostela, Spain Minist Hlth, Ankara, Turkey Council Agr Res & Econ, Rome, Italy Fed Univ Rio Grande, Rio Grande, Brazil India Diabet Res Fdn, Chennai, Tamil Nadu, India Duke NUS Med Sch, Singapore, Singapore ICMR Natl Inst Med Stat, New Delhi, India Singapore Eye Res Inst, Singapore, Singapore Acad Sinica, Taipei, Taiwan Capital Inst Pediat, Beijing, Peoples R China Duke Univ, Durham, NH USA Kailuan Gen Hosp, Tangshan, Peoples R China Univ Oxford, Oxford, England Ahvaz Jundishapur Univ Med Sci, Ahvaz, Iran Gertner Inst Epidemiol & Hlth Policy Res, Ramat Gan, Israel Natl Ctr Publ Hlth & Anal, Sofia, Bulgaria Univ Fribourg, Fribourg, Switzerland Minist Hlth & Welf, Taipei, Taiwan CIBER Epidemiol & Salud Publ, Murcia, Spain Univ Southern Denmark, Odense, Denmark Univ Estadual Paulista, Presidente Prudente, Brazil Med Univ Silesia, Katowice, Poland Charles Univ Prague, Prague, Czech Republic Primary Hlth Care, Floriana, Malta Carol Davila Univ Med & Pharm, Bucharest, Romania Katholieke Univ Leuven, Leuven, Belgium STAT Canada, Ottawa, ON, Canada UMR CNRS MNHN 7206 Ecoanthropol, Marseille, France Agcy Prevent & Social Med, Bregenz, Austria Univ Southampton, Southampton, Hants, England Inst Pasteur, Lille, France Malawi Epidemiol & Intervent Res Unit, Lilongwe, Malawi CIBEROBN, Madrid, Spain Univ Debrecen, Debrecen, Hungary Univ Med & Pharm Carol Davila, Bucharest, Romania Univ Fed Rio Grande do Sul, Porto Alegre, RS, Brazil CNR, Reggio Di Calabria, Italy Eftimie Murgu Univ Resita, Resita, Romania Spanish Agcy Food Safety & Nutr, Madrid, Spain Indian Stat Inst, Kolkata, India Tabriz Hlth Serv Management Res Ctr, Tabriz, Iran Geneva Univ Hosp, Geneva, Switzerland Sciensano, Brussels, Belgium Univ Med Ctr Groningen, Groningen, Netherlands Natl Res Ctr Prevent Med, Moscow, Russia Innovating Hlth Int, Port Au Prince, Haiti Univ Montreal, Montreal, PQ, Canada French Natl Res Inst Sustainable Dev, Montpellier, France French Publ Hlth Agcy, St Maurice, France Mediterranea Cardioctr, Naples, Italy Univ Vale Rio dos Sinos, Sao Leopoldo, Brazil Natl Inst Hyg Epidemiol & Microbiol, Havana, Cuba Natl Council Sci & Tech Res, Buenos Aires, DF, Argentina Minist Hlth & Med Educ, Tehran, Iran Univ Novi Sad, Novi Sad, Serbia Natl Inst Nutr, Hanoi, Vietnam Univ Queensland, Brisbane, Qld, Australia Ist Super Sanita, Rome, Italy Univ Cuenca, Cuenca, Ecuador Helmholtz Zentrum Munchen, Munich, Germany Univ Tehran Med Sci, Tehran, Iran Minist Sante & Hyg Publ, Abidjan, Cote Ivoire Univ Hosp Dusseldorf, Dusseldorf, Germany Natl Inst Cardiol, Warsaw, Poland Beijing Ctr Dis Prevent & Control, Beijing, Peoples R China UMI 3189 ESS, Marseille, France Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA Scuola Super Sant Anna, Pisa, Italy Univ Latvia, Riga, Latvia Minist Hlth & Med Serv, Gizo, Solomon Islands Hormozgan Univ Med Sci, Bandar Abbas, Iran Univ Benin, Benin, Nigeria Univ Skovde, Skovde, Sweden Natl Inst Nutr & Food Technol, Tunis, Tunisia Univ West Indies, Kingston, Jamaica Univ Calif Davis, Davis, CA 95616 USA Univ Stellenbosch, Cape Town, South Africa Univ Duisburg Essen, Duisburg, Germany Karadeniz Tech Univ, Trabzon, Turkey Univ Helsinki, Helsinki, Finland Mashhad Univ Med Sci, Mashhad, Razavi Khorasan, Iran Rafsanjan Univ Med Sci, Rafsanjan, Iran Queens Univ Belfast, Belfast, Antrim, North Ireland Tabriz Univ Med Sci, Tabriz, Iran Fasa Univ Med Sci, Fasa, Iran Shiraz Univ Med Sci, Shiraz, Iran Baqai Med Univ, Karachi, Pakistan Ctr Salud Villanueva Norte, Badajoz, Spain Hosp Don Benito Villanueva Serena, Badajoz, Spain Minist Hlth, Buenos Aires, DF, Argentina Univ Insubria, Varese, Italy Pontificia Univ Catolica Chile, Santiago, Chile Inst Mother & Child Hlth, Warsaw, Poland Swiss Trop & Publ Hlth Inst, Basel, Switzerland Univ Tartu, Tartu, Estonia Univ Sains Malaysia, Kota Baharu, Kelantan, Malaysia Umea Univ, Umea, Sweden Univ Fed Sao Paulo, Sao Paulo, Brazil Hosp Univ Son Espases, Palma De Mallorca, Spain Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil Univ Sumatera Utara, Medan, Indonesia Kindai Univ, Osaka, Japan Kyoto Univ, Kyoto, Japan Med Univ Warsaw, Warsaw, Poland Jagiellonian Univ, Med Coll, Krakow, Poland Minist Salute DG Prevenz Sanit, Rome, Italy Univ Catania, Catania, Italy CIBER Epidemiol & Salud Publ, Alicante, Spain Africa Hlth Res Inst, Mtubatuba, South Africa Univ Geneva, Med Sch, Geneva, Switzerland CIBER Epidemiol & Salud Publ, Barcelona, Spain Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil Univ Utrecht, Utrecht, Netherlands Wageningen Univ, Wageningen, Netherlands Univ Adelaide, Adelaide, SA, Australia Lund Univ, Lund, Sweden Aristotle Univ Thessaloniki, Thessaloniki, Greece Inst Natl Sante & Rech Med, Villejuif, France Minist Hlth, Jerusalem, Israel McGill Univ, Montreal, PQ, Canada Gasol Fdn, Barcelona, Spain PASs Hirszfeld Inst Immunol & Expt Therapy, Wroclaw, Poland Univ Politecn Madrid, Madrid, Spain St Annes Univ Hosp, Brno, Czech Republic Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico Ctr Estudios Diabet AC, Mexico City, DF, Mexico Univ Autonoma Santo Domingo, Santo Domingo, Dominican Rep Minist Hlth, Lisbon, Portugal Inst Clin & Expt Med, Prague, Czech Republic Childrens Mem Hlth Inst, Warsaw, Poland Natl Ctr Cardiovasc Dis, Beijing, Peoples R China Univ Ferrara, Ferrara, Italy Author Sanitaria San Marino, San Marino, CA USA Iceland Heart Assoc, Kopavogur, Iceland Univ Icesi, Cali, Colombia Univ Estadual Montes Claros, Montes Claros, MG, Brazil Kings Coll London, London, England Int Agcy Res Canc, Lyon, France Capital Med Univ, Beijing, Peoples R China Capital Med Univ, Beijing Tongren Hosp, Beijing, Peoples R China Healis Sekhsaria Inst Publ Hlth, Navi Mumbai, India Eternal Heart Care Ctr & Res Inst, Jaipur, Rajasthan, India Univ Ibadan, Ibadan, Nigeria Inst Clin Effectiveness & Hlth Policy, Buenos Aires, DF, Argentina Natl Hlth Insurance Serv, Wonju, South Korea Prevent Metab Disorders Res Ctr, Tehran, Iran Res & Educ Inst Child Hlth, Nicosia, Cyprus Danish Canc Soc Res Ctr, Copenhagen, Denmark Univ West Indies, Cave Hill, Barbados Kermanshah Univ Med Sci, Kermanshah, Iran Univ Eastern Finland, Kuopio, Finland Beijing Inst Ophthalmol, Beijing, Peoples R China Int Hellen Univ, Thessaloniki, Greece Kyushu Univ, Fukuoka, Japan Univ Bergen, Bergen, Norway Tulane Univ, New Orleans, LA USA Natl Res Inst Hlth & Family Planning, Beijing, Peoples R China Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China Univ Pecs, Pecs, Hungary Danish Hlth Author, Copenhagen, Denmark Joep Lange Inst, Amsterdam, Netherlands Univ Fed Pernambuco, Recife, PE, Brazil Oulu Univ Hosp, Oulu, Finland Univ Autonoma Bucaramanga, Bucaramanga, Colombia Swiss Fed Inst Technol, Zurich, Switzerland Chron Dis Res Ctr, Tehran, Iran Univ Hong Kong, Hong Kong, Peoples R China Chinese Univ Hong Kong, Hong Kong, Peoples R China Univ Western Australia, Perth, WA, Australia Kingston Hlth Sci Ctr, Kingston, ON, Canada Fdn Oftalmol Santander, Bucaramanga, Colombia Univ Oran 1, Oran, Algeria Nay Pyi Taw, Independent Publ Hlth Specialist, Nay Pyi Taw, Myanmar Minist Hlth & Sports, Nay Pyi Taw, Myanmar Peking Univ, Beijing, Peoples R China Natl Inst Publ Hlth, Bucharest, Romania Vrije Univ Amsterdam Med Ctr, Amsterdam, Netherlands Amer Univ Beirut, Beirut, Lebanon CIBER Epidemiol & Salud Publ, San Sebastian, Spain Cairo Univ, Cairo, Egypt Erasmus MC, Rotterdam, Netherlands Med Univ Varna, Varna, Bulgaria Univ Tokyo, Tokyo, Japan Deakin Univ, Geelong, Vic, Australia Tokyo Metropolitan Inst Gerontol, Tokyo, Japan Hadassah Univ Med Ctr, Jerusalem, Israel Norwegian Univ Sci & Technol, Trondheim, Norway Univ Melbourne, Melbourne, Vic, Australia Sports Univ Tirana, Tirana, Albania Univ Hosp Ctr Zagreb, Zagreb, Croatia Univ Zagreb, Sch Med, Zagreb, Croatia Heart Fdn, Melbourne, Vic, Australia Guangzhou 12th Hosp, Guangzhou, Peoples R China Univ Eugenio Maria Hostos, Santo Domingo, Dominican Rep Simon Fraser Univ, Burnaby, BC, Canada Inst Mol & Clin Ophthalmol Basel, Basel, Switzerland Univ New South Wales, Sydney, NSW, Australia World Hlth Org Country Off, Delhi, India Guilan Univ Med Sci, Rasht, Iran Inst Publ Hlth, Belgrade, Serbia Univ Opole, Opole, Poland Finnish Inst Hlth & Welf, Helsinki, Finland Gulu Univ, Gulu, Uganda Univ Crete, Iraklion, Greece Sri Venkateswara Univ, Tirupati, Andhra Pradesh, India Sree Chitra Tirunal Inst Med Sci & Technol, Trivandrum, Kerala, India Hellen Med Assoc Obes, Athens, Greece Natl & Kapodistrian Univ Athens, Athens, Greece Maharajgunj Med Campus, Kathmandu, Nepal Aarhus Univ, Aarhus, Denmark Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA Pennington Biomed Res Ctr, Baton Rouge, LA USA Natl Inst Epidemiol, Chennai, Tamil Nadu, India Univ Munster, Munster, Germany Israel Ctr Dis Control, Ramat Gan, Israel Res Inst Primordial Prevent Noncommunicable Dis, Esfahan, Iran Amsterdam UMC Publ Hlth Res Inst, Amsterdam, Netherlands South African Med Res Council, Cape Town, South Africa Kyrgyz State Med Acad, Bishkek, Kyrgyzstan Res Inst Child Nutr, Dortmund, Germany Shahid Beheshti Univ Med Sci, Tehran, Iran Univ Cambridge, Cambridge, England Mazandaran Univ Med Sci, Sari, Iran Hypertens Res Ctr, Esfahan, Iran Med Univ Innsbruck, Innsbruck, Austria Muhimbili Univ Hlth & Allied Sci, Dar Es Salaam, Tanzania Yonsei Univ, Coll Med, Seoul, South Korea Natl Canc Ctr, Goyang Si, South Korea Univ Coll South Denmark, Haderslev, Denmark Stat Austria, Vienna, Austria BP Koirala Inst Hlth Sci, Dharan, Nepal Univ Vienna, Vienna, Austria Tartu Univ Clin, Tartu, Estonia Kansai Med Univ, Hirakata, Osaka, Japan Hungarian Sch Sport Federat, Budapest, Hungary Minist Hlth & Qual Life, Port Louis, Mauritius Univ Hosp Ulm, Ulm, Germany North West Univ, Potchefstroom, South Africa Univ Jyvaskyla, Jyvaskyla, Finland Inst Publ Hlth, Podgorica, Montenegro Amrita Inst Med Sci, Cochin, Kerala, India Inst Endocrinol, Prague, Czech Republic All India Inst Med Sci, New Delhi, India African Populat & Hlth Res Ctr, Nairobi, Kenya Hanoi Univ Publ Hlth, Hanoi, Vietnam Hassan First Univ Settat, Settat, Morocco Minist Hlth, Algiers, Algeria Harokopio Univ, Athens, Greece Sahlgrens Acad, Gothenburg, Sweden Endocrinol & Metab Res Ctr, Tehran, Iran Univ Publ Hlth, Yangon, Myanmar Int Food Policy Res Inst, Dakar, Senegal Natl Univ Singapore, Singapore, Singapore Hong Kong Polytech Univ, Hong Kong, Peoples R China Tampere Univ Hosp, Tampere, Finland Univ Douala, Douala, Cameroon Univ Cape Town, Cape Town, South Africa Natl Inst Hlth Dev, Tallinn, Estonia West Virginia Univ, Morgantown, WV 26506 USA Oswaldo Cruz Fdn Rene Rachou Res Inst, Belo Horizonte, MG, Brazil Natl Taiwan Univ, Taipei, Taiwan Univ Chinese Acad Sci, Shanghai, Peoples R China Uppsala Univ, Uppsala, Sweden Taipei Med Univ, Taipei, Taiwan Sports Med Ctr Minho, Braga, Portugal Univ San Martin Porres, Lima, Peru Consejeria Sanidad Junta Castilla & Leon, Valladolid, Spain Univ Fed Ciencias Saude Porto Alegre, Porto Alegre, RS, Brazil Norrbotten Cty Council, Lulea, Sweden Ilembula Lutheran Hosp, Ilembula, Iran Univ Fed Ouro Preto, Ouro Preto, Brazil Univ Coimbra, Coimbra, Portugal Coimbra Univ Hosp Ctr, Coimbra, Portugal Inst Neurosci Natl Res Council, Padua, Italy Baker Heart & Diabet Inst, Melbourne, Vic, Australia Agr Univ Athens, Athens, Greece Hosp Israelita Albert Einstein, Sao Paulo, Brazil SB RAS Fed Res Ctr Inst Cytol & Genet, Novosibirsk, Russia Univ Otago, Dunedin, New Zealand Univ Padua, Padua, Italy Hellen Mediterranean Univ, Siteia, Greece Loughborough Univ, Loughborough, Leics, England Minist Hlth, Nicosia, Cyprus Lausanne Univ Hosp, Lausanne, Switzerland Escola Nacl Saude Publ Sergio Arouca, Rio De Janeiro, Brazil CIBERCV, Madrid, Spain Mary Immaculate Coll, Limerick, Ireland Emory Univ, Atlanta, GA 30322 USA Hungarian Soc Sports Med, Budapest, Hungary Paracelsus Med Univ, Salzburg, Austria Univ Estadual Centro Oeste, Guarapuava, Brazil Sherikashmir Inst Med Sci, Srinagar, India UiT Arctic Univ Norway, Tromso, Norway ICMR Natl Ctr Dis Informat & Res, Bengaluru, India Cape Peninsula Univ Technol, Cape Town, South Africa Brown Univ, Providence, RI 02912 USA London Sch Hyg & Trop Med, London, England Univ Edinburgh, Edinburgh, Midlothian, Scotland Shahid Sadoughi Univ Med Sci, Tehran, Iran Inst Natl Sante & Rech Med, Lille, France Robert Koch Inst, Berlin, Germany Univ Lisbon, Lisbon, Portugal Womens Social & Hlth Studies Fdn, Trivandrum, Kerala, India Democritus Univ, Alexandroupolis, Greece Grigore T Popa Univ Med & Pharm, Iasi, Romania Univ Firenze, Florence, Italy Ain Shams Univ, Cairo, Egypt Isfahan Cardiovasc Res Ctr, Esfahan, Iran Univ Strasbourg, Strasbourg, France Mulago Hosp, Kampala, Uganda Univ San Carlos, Guatemala City, Guatemala Univ Limpopo, Sovenga, South Africa Univ Med Sci Cienfuegos, Cienfuegos, Cuba Royal Coll Surgeons Ireland, Dublin, Ireland Trobe Univ, Melbourne, Vic, Australia Int Inst Mol & Cell Biol, Warsaw, Poland Inst Conmemorat Gorgas Estudios Salud, Panama City, Panama World Hlth Org Country Off, Lilongwe, Malawi Dept Publ Hlth, Nay Pyi Taw, Myanmar Univ Brescia, Brescia, Italy Minist Hlth & Social Protect, Dushanbe, Tajikistan Univ Limerick, Limerick, Ireland Croatian Inst Publ Hlth, Zagreb, Croatia Univ Kebangsaan Malaysia, Kuala Lumpur, Malaysia Bushehr Univ Med Sci, Bushehr, Iran Ulm Univ, Ulm, Germany Dept Stat, Kuala Lumpur, Malaysia Kobe Univ, Kobe, Hyogo, Japan Suraj Eye Inst, Nagpur, Maharashtra, India UNICEF, Yaounde, Cameroon Univ Med Greifswald, Greifswald, Germany Karolinska Inst, Stockholm, Sweden Natl Inst Hyg & Epidemiol, Hanoi, Vietnam Univ Med & Pharm Ho Chi Minh City, Ho Chi Minh City, Vietnam Hanoi Med Univ, Hanoi, Vietnam LifeDoc Hlth, Memphis, TN USA Heartfile, Islamabad, Pakistan Eastern Mediterranean Publ Hlth Network, Amman, Jordan Univ Manchester, Manchester, Lancs, England State Univ Med & Pharm, Kishinev, Moldova Tachikawa Gen Hosp, Nagaoka, Niigata, Japan Korea Ctr Dis Control & Prevent, Cheongju, South Korea Japan Wildlife Res Ctr, Tokyo, Japan Istanbul Univ, Istanbul, Turkey Minist Hlth, Bandar Seri Begawan, Brunei Univ Fed Parana, Curitiba, Parana, Brazil Univ Madeira, Funchal, Portugal Univ Puerto Rico, San Juan, PR 00936 USA Ctr Clin Res & Prevent, Glostrup, Denmark MRC Lifecourse Epidemiol Unit, Southampton, Hants, England Kwame Nkrumah Univ Sci & Technol, Kumasi, Ghana UniSante, Lausanne, Switzerland Inst Canc Res, Prevent & Clin Network, Florence, Italy Univ Wisconsin, Madison, WI USA Heidelberg Univ, Heidelberg, Germany IRCCS Ente Osped Specializzato Gastroenterol S de, Bari, Italy Zayed Univ, Abu Dhabi, U Arab Emirates Catholic Univ Daegu, Daegu, South Korea Univ Med Pharm Sci & Technol Targu Mures, Targu Mures, Romania Jivandeep Hosp, Anand, Gujarat, India South African Med Res Council, Durban, South Africa Natl Dent Care Ctr Singapore, Singapore, Singapore Univ Malaga, Malaga, Spain Univ Hosp Varese, Varese, Italy Vietnam Natl Heart Inst, Hanoi, Vietnam Clin Med Avanzada Dr Abel Gonzalez, Santo Domingo, Dominican Rep Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany Univ Sarajevo, Sarajevo, Bosnia & Herceg Cardiovasc Prevent Ctr Udine, Udine, Italy Pisa Univ Hosp, Pisa, Italy Minist Hlth & Med Serv, Honiara, Solomon Islands Publ Hlth Agcy Catalonia, Barcelona, Spain Inst Hosp del Mar Invest Med, Barcelona, Spain Ardabil Univ Med Sci, Ardebil, Iran Ctr Dis Prevent & Control, Riga, Latvia Alborz Univ Med Sci, Karaj, Iran Minist Hlth, Hanoi, Vietnam Pure Earth, Dhaka, Bangladesh Inst Epidemiol Dis Control & Res, Dhaka, Bangladesh Univ Turku, Turku, Finland Inst Univ Invest Atenc Primaria Jordi Gol, Girona, Spain Univ Putra Malaysia, Serdang, Malaysia Univ Malaya, Kuala Lumpur, Malaysia Sotiria Hosp, Athens, Greece Univ Valencia, Valencia, Spain Univ Philippines, Manila, Philippines Slovak Acad Sci, Bratislava, Slovakia Nutr Res Fdn, Barcelona, Spain Minas Gerais State Secretariat Hlth, Belo Horizonte, MG, Brazil CS S Agustin Ibsalut, Palma De Mallorca, Spain Amsterdam Inst Global Hlth & Dev, Amsterdam, Netherlands Natl Inst Hlth Doutor Ricardo Jorge, Lisbon, Portugal Univ Nove Julho, Sao Paulo, Brazil Publ Hlth Agcy Canada, Ottawa, ON, Canada Canarian Hlth Serv, Tenerife, Spain Univ Ind Santander, Bucaramanga, Colombia Assoc Calabrese Epatol, Reggio Di Calabria, Italy Univ Minho, Braga, Portugal Fiji Natl Univ, Suva, Fiji Spanish Nutr Fdn, Madrid, Spain Publ Hlth Agcy Sweden, Stockholm, Sweden Inst Food Sci Natl Res Council, Avellino, Italy Sitaram Bhartia Inst Sci & Res, New Delhi, India Kindergarten Avlonari, Evia, Greece Natl Inst Hlth, Lima, Peru Minist Hlth, Jakarta, Indonesia Catalan Dept Hlth, Barcelona, Spain Biodonostia Hlth Res Inst, San Sebastian, Spain Inst Saude Ambiental, Lisbon, Portugal South Karelia Social & Hlth Care Dist, Lappeenranta, Finland McMaster Univ, Hamilton, ON, Canada Natl Canc Ctr, Tokyo, Japan Univ Sao Paulo Clin Hosp, Sao Paulo, Brazil Hosp Italiano Buenos Aires, Buenos Aires, DF, Argentina Rigshosp, Copenhagen, Denmark Acad Med Ctr Univ Amsterdam, Amsterdam, Netherlands Ctr Oral Hlth Serv & Res Midnorway, Trondheim, Norway Lagos State Univ, Coll Med, Lagos, Nigeria Univ Las Palmas Gran Canaria, Las Palmas Gran Canaria, Spain Comenius Univ, Bratislava, Slovakia Natl Ctr Dis Control & Publ Hlth, Tbilisi, Georgia Nippon Med Sch, Tokyo, Japan Sungkyunkwan Univ, Seoul, South Korea Finnish Inst Occupat Hlth, Helsinki, Finland Publ Hlth Promot & Dev Org, Kathmandu, Nepal St Vincents Hosp, Sydney, NSW, Australia Nes Municipal, Aarnes, Norway Hlth Polytech Jakarta II Inst, Jakarta, Indonesia Diponegoro Univ, Semarang, Indonesia Univ Bari, Bari, Italy Inst Reg Sante Publ, Ouidah, Benin Univ Bordeaux, Bordeaux, France Oslo Metropolitan Univ, Oslo, Norway Inst Publ Hlth, Skopje, North Macedonia Univ Leuven, Leuven, Belgium Lamprecht & Stamm Sozialforsch & Beratung AG, Zurich, Switzerland Inst Natl Sante & Rech Med, Nancy, France Univ Bonn, Bonn, Germany Sotiria Hosp, Sotiria, Greece Kalina Malina Kindergarten, Pazardjik, Bulgaria Jikei Univ, Sch Med, Tokyo, Japan Fu Jen Catholic Univ, Taipei, Taiwan Natl Stat Off, Praia, Cape Verde Natl Inst Publ Hlth Natl Inst Hyg, Warsaw, Poland Deakin Univ, Sydney, NSW, Australia Sci Res Inst Maternal & Child Hlth, Ashkhabad, Turkmenistan Univ Lincoln, Lincoln, England Minist Hlth, Amman, Jordan UNICEF, Niamey, Niger Cent Univ Kerala, Kasaragod, India Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands Hlth Serv Murcia, Murcia, Spain Inst Invest Sanitaria Illes Balears, Menorca, Spain Univ Bologna, Bologna, Italy Hellen Hlth Fdn, Athens, Greece Govt Med Coll, Bhavnagar, Gujarat, India Sefako Makgatho Hlth Sci Univ, Ga Rankuwa, South Africa Addis Ababa Univ, Addis Ababa, Ethiopia Minist Hlth, Wellington, New Zealand Univ Ctr Occidental Lisandro Alvarado, Barquisimeto, Venezuela Meharry Med Coll, Nashville, TN 37208 USA Dokuz Eylul Univ, Izmir, Turkey Univ Tampere, Tays Eye Ctr, Tampere, Finland Sabiha Gokcen Ilkokulu, Ankara, Turkey Polytech Inst Porto, Porto, Portugal Icahn Sch Med Mt Sinai, New York, NY 10029 USA Univ CEU San Pablo, Madrid, Spain CNR, Pisa, Italy Univ Miguel Hernandez, Alicante, Spain Vrije Univ Amsterdam, Amsterdam, Netherlands Sunflower Nursery Sch, Craiova, Romania North Karelia Ctr Publ Hlth, Joensuu, Finland Univ Witwatersrand, Johannesburg, South Africa Med Univ Vienna, Vienna, Austria Cork Inst Technol, Cork, Ireland Inst Med Res, Kuala Lumpur, Malaysia Xinjiang Med Univ, Urumqi, Peoples R China Shanghai Educ Dev Co Ltd, Shanghai, Peoples R China Minist Hlth, Auckland, New Zealand Rebro Univ, Rebro, Sweden St Georges Univ London, London, England Univ Indonesia, Jakarta, Indonesia Minist Agr & Rural Affairs, Inst Food & Nutr Dev, Beijing, Peoples R China Fudan Univ, Childrens Hosp, Shanghai, Peoples R China Univ Cyprus, Nicosia, Cyprus Niigata Univ, Niigata, Japan Int Med Univ, Shah Alam, Selangor, Malaysia Hellen Mediterranean Univ, Iraklion, Greece Iran Univ Med Sci, Tehran, Iran Ctr Diabet & Endocrine Care, Srinagar, India Peking Univ First Hosp, Beijing, Peoples R China Jiangsu Prov Ctr Dis Control & Prevent, Nanjing, Peoples R China Sun Yat Sen Univ, Guangzhou, Peoples R China West Kazakhstan Med Univ, Aktobe, Kazakhstan Inner Mongolia Med Univ, Hohhot, Peoples R China Przedszkole 81, Warsaw, Poland Univ Estadual Paulista, Presidente Prudente, Brazil
Published: 2021

29. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

Author: Zhou, B, Carrillo-Larco, Rm, Danaei, G, Riley, Lm, Paciorek, Cj, Stevens, Ga, Gregg, Ew, Bennett, Je, Solomon, B, Singleton, Rk, Sophiea, Mk, Iurilli, Mlc, Lhoste, Vpf, Cowan, Mj, Savin, S, Woodward, M, Balanova, Y, Cifkova, R, Damasceno, A, Elliott, P, Farzadfar, F, He, J, Ikeda, N, Kengne, Ap, Khang, Yh, Kim, Hc, Laxmaiah, A, Lin, Hh, Maira, Pm, Miranda, Jj, Neuhauser, H, Sundstrom, J, Varghese, C, Widyahening, Is, Zdrojewski, T, Ezzati, M, Abarca-Gomez, L, Abdeen, Za, Rahim, Hfa, Abu-Rmeileh, Nm, Acosta-Cazares, B, Adams, Rj, Aekplakorn, W, Afsana, K, Afzal, S, Agdeppa, Ia, Aghazadeh-Attari, J, Aguilar-Salinas, Ca, Agyemang, C, Ahmad, Na, Ahmadi, A, Ahmadi, N, Ahmadizar, F, Ahmed, Sh, Ahrens, W, Ajlouni, K, Al-Raddadi, R, Alarouj, M, Albuhairan, F, Aldhukair, S, Ali, Mm, Alkandari, A, Alkerwi, A, Allin, K, Aly, E, Amarapurkar, Dn, Amougou, N, Amouyel, P, Andersen, Lb, Anderssen, Sa, Anjana, Rm, Ansari-Moghaddam, A, Ansong, D, Aounallah-Skhiri, H, Araujo, J, Ariansen, I, Aris, T, Arku, Re, Arlappa, N, Aryal, Kk, Aspelund, T, Assah, Fk, Assuncao, Mcf, Auvinen, J, Avdicova, M, Azevedo, A, Azimi-Nezhad, M, Azizi, F, Azmin, M, Babu, Bv, Bahijri, S, Balakrishna, N, Bamoshmoosh, M, Banach, M, Banadinovic, M, Bandosz, P, Banegas, Jr, Baran, J, Barbagallo, Cm, Barcelo, A, Barkat, A, Barreto, M, Barros, Ajd, Barros, Mvg, Bartosiewicz, A, Basit, A, Bastos, Jld, Bata, I, Batieha, Am, Batyrbek, A, Baur, La, Beaglehole, R, Belavendra, A, Ben Romdhane, H, Benet, M, Benson, Ls, Berkinbayev, S, Bernabe-Ortiz, A, Bettiol, H, Bezerra, J, Bhagyalaxmi, A, Bhargava, Sk, Bia, D, Biasch, K, Lele, Ecb, Bikbov, Mm, Bista, B, Bjerregaard, P, Bjertness, E, Bjertness, Mb, Bjorkelund, C, Bloch, Kv, Blokstra, A, Bo, S, Bobak, M, Boeing, H, Boggia, Jg, Boissonnet, Cp, Bojesen, Se, Bongard, V, Bonilla-Vargas, A, Bopp, M, Borghs, H, Bovet, P, Boyer, Cb, Braeckman, L, Brajkovich, I, Branca, F, Breckenkamp, J, Brenner, H, Brewster, Lm, Briceno, Y, Brito, M, Bruno, G, Bueno-de-Mesquita, Hb, Bueno, G, Bugge, A, Burns, C, Bursztyn, M, de Leon, Ac, Cacciottolo, J, Cameron, C, Can, G, Candido, Apc, Capanzana, Mv, Capkova, N, Capuano, E, Capuano, V, Cardoso, Vc, Carlsson, Ac, Carvalho, J, Casanueva, Ff, Censi, L, Cervantes-Loaiza, M, Chadjigeorgiou, Ca, Chamukuttan, S, Chan, Aw, Chan, Q, Chaturvedi, Hk, Chaturvedi, N, Chee, Ml, Chen, Cj, Chen, Ff, Chen, Hs, Chen, Sh, Chen, Zm, Cheng, Cy, Cheraghian, B, Dekkaki, Ic, Chetrit, A, Chien, Kl, Chiolero, A, Chiou, St, Chirita-Emandi, A, Chirlaque, Md, Cho, B, Christensen, K, Christofaro, Dg, Chudek, J, Cinteza, E, Claessens, F, Clarke, J, Clays, E, Cohen, E, Concin, H, Cooper, C, Coppinger, Tc, Costanzo, S, Cottel, D, Cowell, C, Craig, Cl, Crampin, Ac, Crujeiras, Ab, Cruz, Jj, Csilla, S, Cui, Lf, Cureau, Fv, Cuschieri, S, D'Arrigo, G, D'Orsi, E, Dallongeville, J, Dankner, R, Dantoft, Tm, Dauchet, L, Davletov, K, De Backer, G, De Bacquer, D, De Curtis, A, de Gaetano, G, De Henauw, S, de Oliveira, Pd, De Ridder, D, De Smedt, D, Deepa, M, Deev, Ad, Degennaro, V, Delisle, H, Demarest, S, Dennison, E, Deschamps, V, Dhimal, M, Di Castelnuovo, Af, Dias-da-Costa, Js, Diaz, A, Dickerson, Tt, Dika, Z, Djalalinia, S, Htp, Do, Dobson, Aj, Donfrancesco, C, Donoso, Sp, Doring, A, Dorobantu, M, Dorr, M, Doua, K, Dragano, N, Drygas, W, Duante, Ca, Duboz, P, Duda, Rb, Dulskiene, V, Dushpanova, A, Dzakula, A, Dzerve, V, Dziankowska-Zaborszczyk, E, Eddie, R, Eftekhar, E, Eggertsen, R, Eghtesad, S, Eiben, G, Ekelund, U, El-Khateeb, M, El Ati, J, Eldemire-Shearer, D, Eliasen, M, Elosua, R, Erasmus, Rt, Erbel, R, Erem, C, Eriksen, L, Eriksson, Jg, Escobedo-de la Pena, J, Eslami, S, Esmaeili, A, Evans, A, Faeh, D, Fakhretdinova, Aa, Fall, Ch, Faramarzi, E, Farjam, M, Fattahi, Mr, Fawwad, A, Felix-Redondo, Fj, Felix, Sb, Ferguson, Ts, Fernandes, Ra, Fernandez-Berges, D, Ferrante, D, Ferrao, T, Ferrari, M, Ferrario, Mm, Ferreccio, C, Ferreira, Hs, Ferrer, E, Ferrieres, J, Figueiro, Th, Fink, G, Fischer, K, Foo, Lh, Forsner, M, Fouad, Hm, Francis, Dk, Grego, Franco, Frikke-Schmidt, R, Frontera, G, Fuchs, Fd, Fuchs, Sc, Fujita, Y, Fumihiko, M, Furdela, V, Furer, A, Furusawa, T, Gaciong, Z, Galbarczyk, A, Galenkamp, H, Galvano, F, Gao, Jl, Gao, P, Garcia-de-la-Hera, M, Garcia, P, Gareta, D, Garnett, Sp, Gaspoz, Jm, Gasull, M, Gazzinelli, A, Gehring, U, Geleijnse, Jm, George, R, Ghanbari, A, Ghasemi, E, Gheorghe-Fronea, Of, Ghimire, A, Gialluisi, A, Giampaoli, S, Gieger, C, Gill, Tk, Giovannelli, J, Gironella, G, Giwercman, A, Gkiouras, K, Goldberg, M, Goldsmith, Ra, Gomez, Lf, Gomula, A, da Silva, Bgc, Goncalves, H, Goncalves, M, Gonzalez-Chica, Da, Gonzalez-Gross, M, Gonzalez-Rivas, Jp, Gonzalez-Villalpando, C, Gonzalez-Villalpando, Me, Gonzalez, Ar, Gorbea, Mb, Gottrand, F, Graff-Iversen, S, Grafnetter, D, Grajda, A, Grammatikopoulou, Mg, Gregor, Rd, Grodzicki, T, Grosso, G, Gruden, G, Df, Gu, Guan, Op, Gudmundsson, Ef, Gudnason, V, Guerrero, R, Guessous, I, Guimaraes, Al, Gulliford, Mc, Gunnlaugsdottir, J, Gunter, Mj, Gupta, Pc, Gupta, R, Gureje, O, Gurzkowska, B, Gutierrez, L, Gutzwiller, F, Ha, S, Hadaegh, F, Haghshenas, R, Hakimi, H, Halkjaer, J, Hambleton, Ir, Hamzeh, B, Hange, D, Hanif, Aam, Hantunen, S, Hao, J, Hardman, Cm, Kumar, Rh, Hashemi-Shahri, Sm, Hata, J, Haugsgjerd, T, Hayes, Aj, Yn, He, Heier, M, Hendriks, Me, Henrique, Rd, Henriques, A, Cadena, Lh, Herrala, S, Heshmat, R, Hill, Ag, Sy, Ho, Sc, Ho, Hobbs, M, Holdsworth, M, Homayounfar, R, Dinc, Gh, Horimoto, Arvr, Hormiga, Cm, Horta, Bl, Houti, L, Howitt, C, Htay, Tt, Htet, As, Htike, Mmt, Yh, Hu, Huerta, Jm, Huhtaniemi, It, Huiart, L, Huisman, M, Husseini, As, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, Ag, Ibrahim, Mm, Wong, Ni, Ikram, Ma, Iotova, V, Irazola, Ve, Ishida, T, Isiguzo, Gc, Islam, M, Islam, Sms, Iwasaki, M, Jackson, Rt, Jacobs, Jm, Jaddou, Hy, Jafar, T, James, K, Jamrozik, K, Janszky, I, Janus, E, Jarvelin, Mr, Jasienska, G, Jelakovic, A, Jelakovic, B, Jennings, G, Jha, Ak, Jiang, Cq, Jimenez, Ro, Jockel, Kh, Joffres, M, Johansson, M, Jokelainen, Jj, Jonas, Jb, Jorgensen, T, Joshi, P, Joukar, F, Jozwiak, J, Juolevi, A, Jurak, G, Juresa, V, Kaaks, R, Kafatos, A, Kajantie, Eo, Kalmatayeva, Z, Kalpourtzi, N, Kalter-Leibovici, O, Kampmann, Fb, Kannan, S, Karaglani, E, Karhus, Ll, Karki, Kb, Katibeh, M, Katz, J, Kauhanen, J, Kaur, P, Kavousi, M, Kazakbaeva, Gm, Keil, U, Boker, Lk, Keinanen-Kiukaanniemi, S, Kelishadi, R, Kemper, Hcg, Keramati, M, Kerimkulova, A, Kersting, M, Key, T, Khader, Ys, Khalili, D, Khaw, Kt, Kheiri, B, Kheradmand, M, Khosravi, A, Kiechl-Kohlendorfer, U, Kiechl, S, Killewo, J, Kim, Dw, Kim, J, Klakk, H, Klimek, M, Klumbiene, J, Knoflach, M, Kolle, E, Kolsteren, P, Kontto, Jp, Korpelainen, R, Korrovits, P, Kos, J, Koskinen, S, Kouda, K, Kowlessur, S, Koziel, S, Kratenova, J, Kriaucioniene, V, Kristensen, Pl, Krokstad, S, Kromhout, D, Kruger, Hs, Kubinova, R, Kuciene, R, Kujala, Um, Kulaga, Z, Kumar, Rk, Kurjata, P, Kusuma, Ys, Kutsenko, V, Kuulasmaa, K, Kyobutungi, C, Laatikainen, T, Lachat, C, Laid, Y, Lam, Th, Landrove, O, Lanska, V, Lappas, G, Larijani, B, Latt, Ts, Le Coroller, G, Bao, Kln, Le, THUY DUNG, Lee, J, Lehmann, N, Lehtimaki, T, Lemogoum, D, Levitt, Ns, Yp, Li, Lilly, Cl, Lim, Wy, Lima-Costa, Mf, Lin, X, Lin, Yt, Lind, L, Lingam, V, Linneberg, A, Lissner, L, Litwin, M, Wc, Lo, Loit, Hm, Lopez-Garcia, E, Lopez, T, Lotufo, Pa, Lozano, Je, Lovrencic, Il, Lukrafka, Jl, Luksiene, D, Lundqvist, A, Lundqvist, R, Lunet, N, Lustigova, M, Luszczki, E, Gs, Ma, Ma, J, Machado-Coelho, Gll, Machado-Rodrigues, Am, Macia, E, Macieira, Lm, Madar, Aa, Maggi, S, Magliano, Dj, Magriplis, E, Mahasampath, G, Maire, B, Majer, M, Makdisse, M, Malekzadeh, F, Malekzadeh, R, Malhotra, R, Mallikharjuna, K, Malyutina, Sk, Maniego, Lv, Manios, Y, Mann, Ji, Mansour-Ghanaei, F, Manzato, E, Marcil, A, Margozzini, P, Marild, Sb, Glavic, Mm, Marques-Vidal, P, Marques, Lp, Marrugat, J, Martorell, R, Mascarenhas, Lp, Matasin, M, Mathiesen, Eb, Mathur, P, Matijasevich, A, Matlosz, P, Matsha, Te, Mavrogianni, C, Mbanya, Jcn, Posso, Ajm, Mcfarlane, Sr, Mcgarvey, St, Mclachlan, S, Mclean, Rm, Mclean, Sb, Mcnulty, Ba, Benchekor, Sm, Medzioniene, J, Mehdipour, P, Mehlig, K, Mehrparvar, Ah, Meirhaeghe, A, Meisinger, C, Montano, Cm, Menezes, Amb, Menon, Gr, Mereke, A, Meshram, Ii, Metspalu, A, Meyer, He, Mi, J, Michels, N, Mikkel, K, Milkowska, K, Miller, Jc, Minderico, Cs, Mini, Gk, Mirjalili, Mr, Mirrakhimov, E, Misigoj-Durakovic, M, Modesti, Pa, Moghaddam, Ss, Mohajer, B, Mohamed, Mk, Mohamed, Sf, Mohammad, K, Mohammadi, Mr, Mohammadi, Z, Mohammadifard, N, Mohammadpourhodki, R, Mohan, V, Mohanna, S, Yusoff, Mfm, Mohebbi, I, Mohebi, F, Moitry, M, Mollehave, Lt, Molnar, D, Momenan, A, Mondo, Ck, Monterrubio-Flores, E, Monyeki, Kdk, Moon, Js, Moosazadeh, M, Moreira, Lb, Morejon, A, Moreno, La, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mostafavi, Sa, Mota, J, Motlagh, Me, Motta, J, Moura-dos-Santos, Ma, Mridha, Mk, Msyamboza, Kp, Tt, Mu, Muhihi, Aj, Muiesan, Ml, Muller-Nurasyid, M, Murphy, N, Mursu, J, Musa, Ki, Milanovic, Sm, Musil, V, Mustafa, N, Nabipour, I, Naderimagham, S, Nagel, G, Naidu, Bm, Najafi, F, Nakamura, H, Namesna, J, Nang, Eek, Nangia, Vb, Narake, S, Ndiaye, Nc, Neal, Wa, Nejatizadeh, A, Nenko, I, Neovius, M, Neuhauser, Hk, Nguyen, Ct, Nguyen, Nd, Nguyen, Qv, Nguyen, Qn, Nieto-Martinez, Re, Niiranen, Tj, Nikitin, Yp, Ninomiya, T, Nishtar, S, Njelekela, Ma, Noale, M, Noboa, Oa, Noorbala, Aa, Norat, T, Nordendahl, M, Nordestgaard, Bg, Noto, D, Nowak-Szczepanska, N, Al Nsour, M, Nunes, B, O'Neill, Tw, O'Reilly, D, Ochimana, C, Oda, E, Odili, An, Oh, K, Ohara, K, Ohtsuka, R, Olie, V, Olinto, Mta, Oliveira, Io, Omar, Ma, Onat, A, Ong, Sk, Ono, Lm, Ordunez, P, Ornelas, R, Ortiz, Pj, Osmond, C, Ostojic, Sm, Ostovar, A, Otero, Ja, Overvad, K, Owusu-Dabo, E, Paccaud, Fm, Padez, C, Pahomova, E, de Paiva, Km, Pajak, A, Palli, D, Palmieri, L, Pan, Wh, Panda-Jonas, S, Panza, F, Paoli, M, Papandreou, D, Park, Sw, Park, S, Parnell, Wr, Parsaeian, M, Pasquet, P, Patel, Nd, Pavlyshyn, H, Pecin, I, Pednekar, Ms, Pedro, Jm, Peer, N, Peixoto, Sv, Peltonen, M, Pereira, Ac, Peres, Kgda, Peres, Ma, Peters, A, Petkeviciene, J, Peykari, N, Pham, St, Pichardo, Rn, Pigeot, I, Pikhart, H, Pilav, A, Pilotto, L, Pitakaka, F, Piwonska, A, Pizarro, An, Plans-Rubio, P, Polasek, O, Porta, M, Poudyal, A, Pourfarzi, F, Pourshams, A, Poustchi, H, Pradeepa, R, Price, Aj, Price, Jf, Providencia, R, Puhakka, Se, Puiu, M, Punab, M, Qasrawi, Rf, Qorbani, M, Queiroz, D, Bao, Tq, Radic, I, Radisauskas, R, Rahimikazerooni, S, Rahman, M, Raitakari, O, Raj, M, Rakhimova, Em, Rao, Sr, Ramachandran, A, Ramos, E, Rampal, L, Rampal, S, Reina, Dar, Rarra, V, Rech, Cr, Redon, J, Reganit, Pfm, Regecova, V, Revilla, L, Rezaianzadeh, A, Ribeiro, R, Riboli, E, Richter, A, Rigo, F, de Wit, Tfr, Ritti-Dias, Rm, Robitaille, C, Rodriguez-Artalejo, F, Rodriguez-Perez, Md, Rodriguez-Villamizar, La, Roggenbuck, U, Rojas-Martinez, R, Romaguera, D, Romeo, El, Rosengren, A, Roy, Jgr, Rubinstein, A, Ruidavets, Jb, Ruiz-Betancourt, Bs, Ruiz-Castell, M, Rusakova, Ia, Russo, P, Rutkowski, M, Sabanayagam, C, Sabbaghi, H, Sachdev, Hs, Sadjadi, A, Safarpour, Ar, Safi, S, Safiri, S, Saidi, O, Sakarya, S, Saki, N, Salanave, B, Martinez, Es, Salmeron, D, Salomaa, V, Salonen, Jt, Salvetti, M, Sanchez-Abanto, J, Sans, S, Santos, Da, Santos, Is, Santos, Lc, Santos, Mp, Santos, R, Saramies, Jl, Sardinha, Lb, Sarganas, G, Sarrafzadegan, N, Sathish, T, Saum, Ku, Savva, S, Sawada, N, Sbaraini, M, Scazufca, M, Schaan, Bd, Schargrodsky, H, Schipf, S, Schmidt, Co, Schnohr, P, Schottker, B, Schramm, S, Schultsz, C, Schutte, Ae, Sebert, S, Sein, Aa, Sen, A, Senbanjo, Io, Sepanlou, Sg, Servais, J, Shalnova, Sa, Shamah-Levy, T, Shamshirgaran, M, Shanthirani, Cs, Sharafkhah, M, Sharma, Sk, Shaw, Je, Shayanrad, A, Shayesteh, Aa, Shi, Zm, Shibuya, K, Shimizu-Furusawa, H, Shin, Dw, Shirani, M, Shiri, R, Shrestha, N, Si-Ramlee, K, Siani, A, Siantar, R, Sibai, Am, Silva, Crd, Silva, Das, Simon, M, Simons, J, Simons, La, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Hk, So, Soares, Fc, Sobngwi, E, Soderberg, S, Soemantri, A, Sofat, R, Solfrizzi, V, Somi, Mh, Sonestedt, E, Song, Y, Sorensen, Tia, Sorgjerd, Ep, Soric, M, Jerome, Cs, Soumare, A, Sparboe-Nilsen, B, Sparrenberger, K, Staessen, Ja, Starc, G, Stavreski, B, Steene-Johannessen, J, Stehle, P, Stein, Ad, Stergiou, Gs, Stessman, J, Stieber, J, Stockl, D, Stocks, T, Stokwiszewski, J, Stronks, K, Strufaldi, Mw, Suka, M, Sun, Ca, Sung, Yt, Suriyawongpaisal, P, Rg, Sy, Syddall, He, Sylva, Rc, Szklo, M, Tai, Es, Tammesoo, Ml, Tamosiunas, A, Tan, Ej, Tang, X, Tanser, F, Tao, Y, Tarawneh, Mr, Tarqui-Mamani, Cb, Taylor, A, Taylor, J, Tebar, Wr, Tell, Gs, Tello, T, Tham, Yc, Thankappan, Kr, Theobald, H, Theodoridis, X, Thijs, L, Thinggaard, M, Thomas, N, Thorand, B, Thuesen, Bh, Timmermans, Ej, Tjandrarini, Dh, Tjonneland, A, Toft, U, Tolonen, Hk, Tolstrup, Js, Topbas, M, Topor-Madry, R, Tormo, Mj, Tornaritis, Mj, Torrent, M, Torres-Collado, L, Touloumi, G, Traissac, P, Triantafyllou, A, Trichopoulos, D, Trichopoulou, A, Trinh, Oth, Trivedi, A, Tshepo, L, Tsugane, S, Tuliakova, Am, Tulloch-Reid, Mk, Tullu, F, Tuomainen, Tp, Tuomilehto, J, Turley, Ml, Twig, G, Tynelius, P, Tzourio, C, Ueda, P, Ugel, E, Ulmer, H, Uusitalo, Hmt, Valdivia, G, Valvi, D, van Dam, Rm, van den Born, Bj, Van der Heyden, J, van der Schouw, Yt, Van Herck, K, Minh, Hv, Van Schoor, Nm, van Valkengoed, Igm, van Zutphen, Em, Vanderschueren, D, Vanuzzo, D, Varbo, A, Vasan, Sk, Vega, T, Veidebaum, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, Wmm, Verstraeten, R, Victora, Cg, Viet, L, Villalpando, S, Vineis, P, Vioque, J, Virtanen, Jk, Visvikis-Siest, S, Viswanathan, B, Vlasoff, T, Vollenweider, P, Voutilainen, A, Wade, An, Walton, J, Wambiya, Eoa, Bebakar, Wmw, Mohamud, Wnw, Wanderley, Rd, Wang, Md, Wang, Nl, Wang, Q, Wang, Xj, Wang, Yx, Wang, Yw, Wannamethee, Sg, Wareham, N, Wei, Wb, Weres, A, Werner, B, Whincup, Ph, Widhalm, K, Wiecek, A, Wilks, Rj, Willeit, J, Willeit, P, Williams, Ea, Wilsgaard, T, Wojtyniak, B, Wong-McClure, Ra, Wong, A, Wong, Ty, Woo, J, Fc, Wu, Sl, Wu, Wyszynska, J, Hq, Xu, Xu, L, Yaacob, Na, Yan, Wl, Yang, L, Yang, Xg, Yang, Y, Yasuharu, T, Xw, Ye, Yiallouros, Pk, Yoosefi, M, Yoshihara, A, You, Sl, Younger-Coleman, No, Yusoff, Af, Zainuddin, Aa, Zakavi, Sr, Zamani, F, Zambon, S, Zampelas, A, Zapata, Me, Zaw, Kk, Zejglicova, K, Vrkic, Tz, Zeng, Y, Zhang, Lx, Zhang, Zy, Zhao, D, Zhao, Mh, Zhen, Sq, Zheng, Yf, Zholdin, B, Zhu, D, Zins, M, Zitt, E, Zocalo, Y, Zoghlami, N, Cisneros, Jz, Borghs, Herman, Claessens, Frank, Staessen, Jan, Thijs, Lutgarde, Vanderschueren, Dirk, Zhang, Zhen-Yu, Imperial Coll London, Harvard TH Chan Sch Publ Hlth, WHO, Univ Calif Berkeley, Univ New South Wales, Natl Med Res Ctr Therapy & Prevent Med, Charles Univ Prague, Thomayer Hosp, Eduardo Mondlane Univ, Noncommunicable Dis Res Ctr, Tulane Univ, Natl Inst Biomed Innovat Hlth & Nutr, South African Med Res Council, Seoul Natl Univ, Yonsei Univ, ICMR Natl Inst Nutr, Natl Taiwan Univ, Pontificia Univ Catolica Chile, Univ Peruana Cayetano Heredia, Robert Koch Inst, Uppsala Univ, Univ Indonesia, Med Univ Gdansk, Univ Ghana, Caja Costarricense Seguro Social, Al Quds Univ, Qatar Univ, Birzeit Univ, Inst Mexicano Seguro Social, Flinders Univ S Australia, Mahidol Univ, BRAC Univ, Univ Copenhagen, Copenhagen Univ Hosp, Food & Nutr Res Inst, Urmia Univ Med Sci, Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Univ Amsterdam, Minist Hlth, Modeling Hlth Res Ctr, Shahid Sadoughi Univ Med Sci, Erasmus MC, Univ Oslo, Leibniz Inst Prevent Res & Epidemiol BIPS, Natl Ctr Diabet Endocrinol & Genet, King Abdulaziz Univ, Dasman Diabet Inst, Aldara Hosp & Med Ctr, King Abdullah Int Med Res Ctr, Luxembourg Inst Hlth, Bispebjerg, Frederiksberg Univ Hosp, WHO Reg Off Eastern Mediterranean, Bombay Hosp & Med Res Ctr, CNRS, Univ Lille, Lille Univ Hosp, Western Norway Univ Appl Sci, Norwegian Sch Sport Sci, Madras Diabet Res Fdn, Zahedan Univ Med Sci, Kwame Nkrumah Univ Sci & Technol, Natl Inst Publ Hlth, Univ Porto, Norwegian Inst Publ Hlth, Univ Massachusetts, Abt Associates Inc, Univ Iceland, Univ Yaounde I, Univ Fed Pelotas, Univ Oulu, Oulu Univ Hosp, Banska Bystr Reg Author Publ Hlth, Neyshabur Univ Med Sci, Res Inst Endocrine Sci, Indian Council Med Res, Univ Sci & Technol, Med Univ Lodz, Univ Zagreb, Univ Autonoma Madrid CIBERESP, Univ Rzeszow, Univ Palermo, Pan Amer Hlth Org, Mohammed V Univ Rabat, Natl Inst Hlth Doutor Ricardo Jorge, NOVA Univ Lisbon, Univ Pernambuco, Baqai Inst Diabetol & Endocrinol, Universidade Federal de Santa Catarina (UFSC), Dalhousie Univ, Jordan Univ Sci & Technol, Al Farabi Kazakh Natl Univ, Univ Sydney, Univ Auckland, Christian Med Coll Vellore, Univ Tunis El Manar, Cafam Univ Fdn, Univ Utah, Kazakh Natl Med Univ, Lithuanian Univ Hlth Sci, Universidade de São Paulo (USP), BJ Med Coll, Sunder Lal Jain Hosp, Univ Republica, Univ Strasbourg, Inst Med Res & Med Plant Studies, Ufa Eye Res Inst, Nepal Hlth Res Council, Univ Southern Denmark, Univ Gothenburg, Universidade Federal do Rio de Janeiro (UFRJ), Natl Inst Publ Hlth & Environm, Univ Turin, UCL, German Inst Human Nutr, Ctr Educ Med & Invest Clin, Toulouse Univ, Univ Zurich, Univ Hosp KU Leuven, Unisante, Univ Ghent, Univ Cent Venezuela, Bielefeld Univ, German Canc Res Ctr, Univ Andres, Inst Politecn Lisboa, Univ Zaragoza, Univ Coll Copenhagen, Munster Technol Univ, Hadassah Univ, Univ La Laguna, Univ Malta, Canadian Fitness & Lifestyle Res Inst, Istanbul Univ Cerrahpasa, Univ Fed Juiz de Fora, Gaetano Fucito Hosp, Karolinska Inst, Santiago Compostela Univ, Council Agr Res & Econ, Res & Educ Inst Child Hlth, India Diabet Res Fdn, Duke NUS Med Sch, ICMR Natl Inst Med Stat, Singapore Eye Res Inst, Acad Sinica, Capital Inst Pediat, Duke Univ, Kailuan Gen Hosp, Univ Oxford, Ahvaz Jundishapur Univ Med Sci, Gertner Inst Epidemiol & Hlth Policy Res, Univ Bern, Minist Hlth & Welf, Victor Babes Univ Med & Pharm Timisoara, CIBER Epidemiol & Salud Publ, Universidade Estadual Paulista (UNESP), Med Univ Silesia, Carol Davila Univ Med & Pharm, Katholieke Univ Leuven, STAT Canada, Agcy Prevent & Social Med, Univ Southampton, IRCCS Neuromed, Inst Pasteur, Malawi Epidemiol & Intervent Res Unit, CIBEROBN, Univ Autonoma Madrid, Univ Debrecen, Univ Fed Rio Grande do Sul, CNR, Geneva Univ Hosp, Innovating Hlth Int, Univ Montreal, Sciensano, French Publ Hlth Agcy, Mediterranea Cardioctr, Univ Vale Rio dos Sinos, Natl Council Sci & Tech Res, Minist Hlth & Med Educ, Natl Inst Nutr, Univ Queensland, Ist Super Sanita, Univ Cuenca, Helmholtz Zentrum Munchen, Univ Med Greifswald, Minist Sante & Hyg Publ, Univ Hosp Dusseldorf, Natl Inst Cardiol, IRL 3189 ESS, Beth Israel Deaconess Med Ctr, Harvard Med Sch, Scuola Super Sant Anna, Univ Latvia, Minist Hlth & Med Serv, Hormozgan Univ Med Sci, Univ Tehran Med Sci, Univ Skovde, Natl Inst Nutr & Food Technol, Univ West Indies, Inst Hosp Mar Invest Med, CIBERCV, Univ Stellenbosch, Univ Duisburg Essen, Karadeniz Tech Univ, Univ Helsinki, Mashhad Univ Med Sci, Rafsanjan Univ Med Sci, Queens Univ Belfast, Tabriz Univ Med Sci, Fasa Univ Med Sci, Shiraz Univ Med Sci, Baqai Med Univ, Ctr Salud Villanueva Norte, Hosp Don Benito Villanueva de la Serena, Univ Insubria, Univ Fed Alagoas, Swiss Trop & Publ Hlth Inst, Univ Basel, Univ Tartu, Univ Sains Malaysia, Umea Univ, Universidade Federal de São Paulo (UNIFESP), Hosp Univ Son Espases, Hosp Clin Porto Alegre, Kindai Univ, Kyoto Univ, I Horbachevsky Ternopil Natl Med Univ, Tel Aviv Univ, Hebrew Univ Jerusalem, Med Univ Warsaw, Jagiellonian Univ Med Coll, Univ Catania, Peking Univ, Wuqu Kawoq, Africa Hlth Res Inst, Univ Geneva, Universidade Federal de Minas Gerais (UFMG), Univ Utrecht, Wageningen Univ, Med Res Fdn, BP Koirala Inst Hlth Sci, Univ Adelaide, Lund Univ, Aristotle Univ Thessaloniki, Inst Natl Sante & Rech Med, Paris Univ, Pontificia Univ Javeriana, PASs Hirszfeld Inst Immunol & Expt Therapy, Univ Agostinho Neto, Univ Politecn Madrid, Int Clin Res Ctr, Ctr Estudios Diabet AC, Univ Autonoma Santo Domingo, Natl Inst Hyg Epidemiol & Microbiol, Inst Clin & Expt Med, Childrens Mem Hlth Inst, Int Hellen Univ, Natl Ctr Cardiovasc Dis, Iceland Heart Assoc, Univ ICESI, Univ Estadual Montes Claros, Kings Coll London, Int Agcy Res Canc, Healis Sekhsaria Inst Publ Hlth, Eternal Heart Care Ctr & Res Inst, Univ Ibadan, Inst Clin Effectiveness & Hlth Policy, Natl Hlth Insurance Serv, Prevent Metab Disorders Res Ctr, Danish Canc Soc Res Ctr, Kermanshah Univ Med Sci, BRAC James P Grant Sch Publ Hlth, Univ Eastern Finland, Beijing Inst Ophthalmol, Universidade Federal de Pernambuco (UFPE), Kyushu Univ, Univ Bergen, Chinese Ctr Dis Control & Prevent, Joep Lange Inst, Chron Dis Res Ctr, Univ Hong Kong, Chinese Univ Hong Kong, Univ Western Australia, French Natl Res Inst Sustainable Dev, Celal Bayar Univ, Fdn Oftalmol Santander, Univ Oran 1, Minist Hlth & Sports, Sante Publ France, Vrije Univ Amsterdam Med Ctr, Amer Univ Beirut, Cairo Univ, Med Univ Varna, Univ Tokyo, Universidade Estadual de Maringá (UEM), Hosp Sick Children, Deakin Univ, Tokyo Metropolitan Inst Gerontol, Hadassah Univ Med Ctr, Norwegian Univ Sci & Technol, Univ Melbourne, Univ Hosp Ctr Zagreb, Heart Fdn, Guangzhou 12th Hosp, Univ Eugenio Maria Hostos, Simon Fraser Univ, Inst Mol & Clin Ophthalmol Basel, WHO Country Off, Guilan Univ Med Sci, Univ Opole, Finnish Inst Hlth & Welf, Univ Ljubljana, Univ Crete, Natl & Kapodistrian Univ Athens, Sree Chitra Tirunal Inst Med Sci & Technol, Harokopio Univ, Maharajgunj Med Campus, Aarhus Univ, Johns Hopkins Bloomberg Sch Publ Hlth, Natl Inst Epidemiol, Univ Munster, Israel Ctr Dis Control, Res Inst Primordial Prevent Noncommunicable Dis, Amsterdam UMC Publ Hlth Res Inst, Kyrgyz State Med Acad, Res Inst Child Nutr, Shahid Beheshti Univ Med Sci, Univ Cambridge, Mazandaran Univ Med Sci, Hypertens Res Ctr, Med Univ Innsbruck, VASCage, Muhimbili Univ Hlth & Allied Sci, Natl Canc Ctr, Univ Coll South Denmark, Oulu Deaconess Inst Fdn, Tartu Univ Clin, Kansai Med Univ, Minist Hlth & Wellness, Univ Groningen, North West Univ, Amrita Inst Med Sci, All India Inst Med Sci, African Populat & Hlth Res Ctr, Minist Salud Publ, Sahlgrens Acad, Endocrinol & Metab Res Ctr, Univ Publ Hlth, Natl Univ Singapore, Tampere Univ Hosp, Tampere Univ, Univ Douala, Univ Cape Town, West Virginia Univ, Oswaldo Cruz Fdn Rene Rachou Res Inst, Shanghai Inst Nutr & Hlth, Taipei Med Univ, Natl Inst Hlth Dev, Univ San Martin de Porres, Consejeria Sanidad Junta Castilla & Leon, Univ Fed Ciencias Saude Porto Alegre, Norrbotten Cty Council, Univ Fed Ouro Preto, Univ Coimbra, Coimbra Univ Hosp Ctr, Inst Neurosci Natl Res Council, Baker Heart & Diabet Inst, Agr Univ Athens, Hosp Israelita Albert Einstein, SB RAS Fed Res Ctr Inst Cytol & Genet, Univ Otago, Univ Padua, Gothenburg Univ, Univ Rijeka, Lausanne Univ Hosp, Univ Lausanne, Escola Nacl Saude Publ Sergio Arouca, Emory Univ, Univ Estadual Centro Oeste, UiT Arctic Univ Norway, ICMR Natl Ctr Dis Informat & Res, Cape Peninsula Univ Technol, Inst Conmemorat Gorgas Estudios Salud, Brown Univ, Univ Edinburgh, Univ Coll Dublin, Inst Nutr Ctr Amer & Panama, Univ Lisbon, Womens Social & Hlth Studies Fdn, Univ Firenze, Ain Shams Univ, Psychiat & Psychol Res Canter, Isfahan Cardiovasc Res Ctr, Strasbourg Univ Hosp, Univ Pecs, Mulago Hosp, Univ Limpopo, Univ Med Sci Cienfuegos, Royal Coll Surgeons Ireland, La Trobe Univ, Int Inst Mol & Cell Biol, Dept Publ Hlth, Univ Brescia, Ludwig Maximilians Univ Munchen, Croatian Inst Publ Hlth, Univ Kebangsaan Malaysia, Bushehr Univ Med Sci, Ulm Univ, Dept Stat, Kobe Univ, Suraj Eye Inst, Natl Inst Hyg & Epidemiol, Univ Med & Pharm Ho Chi Minh City, Natl Hosp Endocrinol, Hanoi Med Univ, LifeDoc Hlth, Univ Turku, Heartfile, Eastern Mediterranean Publ Hlth Network, Univ Manchester, Tachikawa Gen Hosp, Univ Abuja, Korea Ctr Dis Control & Prevent, Japan Wildlife Res Ctr, Istanbul Univ, Univ Fed Parana, Univ Madeira, Univ Novi Sad, Osteoporosis Res Ctr, UniSante, Inst Canc Res Prevent & Clin Network, Inst Clin & Sci Ophthalmol & Acupuncture Jonas, IRCCS Ente Osped Specializzato Gastroenterol S de, Zayed Univ, Catholic Univ Daegu, Jivandeep Hosp, Ctr Invest Saude Angola, Griffith Univ, Natl Dent Care Ctr Singapore, Vietnam Natl Heart Inst, Clin Med Avanzada Dr Abel Gonzalez, Univ Sarajevo, Cardiovasc Prevent Ctr Udine, Publ Hlth Agcy Catalonia, Univ Split, Ardabil Univ Med Sci, London Sch Hyg & Trop Med, Alborz Univ Med Sci, Pure Earth, Univ Putra Malaysia, Univ Malaya, Sotiria Hosp, Univ Valencia, Univ Philippines, Slovak Acad Sci, Univ San Martin Porres, Minas Gerais State Secretariat Hlth, CS S Agustin Ibsalut, Amsterdam Inst Global Hlth & Dev, Univ Nove de Julho, Publ Hlth Agcy Canada, Canarian Hlth Serv, Univ Ind Santander, Assoc Calabrese Epatol, Sahlgrens Univ Hosp, Sitaram Bhartia Inst Sci & Res, Koc Univ, Natl Inst Hlth, Catalan Dept Hlth, South Karelia Social & Hlth Care Dist, German Ctr Cardiovasc Res, McMaster Univ, Hosp Italiano Buenos Aires, Acad Med Ctr Univ Amsterdam, George Inst Global Hlth, Ctr Oral Hlth Serv & Res Mid Norway, Lagos State Univ, Nippon Med Sch, Sungkyunkwan Univ, Shahrekord Univ Med Sci, Finnish Inst Occupat Hlth, Publ Hlth Promot & Dev Org, St Vincents Hosp, Diponegoro Univ, Univ Bari, Inst Reg Sante Publ, Univ Bordeaux, Oslo Metropolitan Univ, Univ Leuven, Univ Bonn, Natl Inst Hyg, Jikei Univ, Fu Jen Catholic Univ, Natl Stat Off, Univ Lincoln, Cent Univ Kerala, Amsterdam Publ Hlth Res Inst, Natl Inst Hlth Res & Dev, Hlth Serv Murcia, Inst Invest Sanitaria Illes Balears, CIBER Epidemiol Salud Publ, Hellen Hlth Fdn, Govt Med Coll, Sefako Makgatho Hlth Sci Univ, Addis Ababa Univ, Israel Def Forces Med Corps, Univ Ctr Occidental Lisandro Alvarado, Univ Tampere, Icahn Sch Med Mt Sinai, Hanoi Univ Publ Hlth, Inst Trop Med, Univ Miguel Hernandez, Univ Lorraine, North Karelia Ctr Publ Hlth, Univ Witwatersrand, Inst Med Res, Capital Med Univ, Xinjiang Med Univ, Shanghai Educ Dev Co Ltd, Orebro Univ, St Georges Univ London, Med Univ Vienna, Komfo Anokye Teaching Hosp, Minist Agr & Rural Affairs, Fudan Univ, Shanghai Educ Dev, Univ Cyprus, Niigata Univ, Iran Univ Med Sci, Ctr Estudios Nutr Infantil, Jiangsu Prov Ctr Dis Control & Prevent, Sun Yat Sen Univ, West Kazakhstan Med Univ, Inner Mongolia Med Univ, Éco-Anthropologie (EAE), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Universitas Indonesia (UI ), Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire (IGE-PCV), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Clinicum, Research Programs Unit, Johan Eriksson / Principal Investigator, Department of General Practice and Primary Health Care, University of Helsinki, HUS Helsinki and Uusimaa Hospital District, Department of Public Health, Tampere University, Clinical Medicine, Department of Clinical Chemistry, Eye Centre, Wellcome Trust, Epidemiology, Radiology & Nuclear Medicine, Éco-Anthropologie (EA), Cohortes épidémiologiques en population (CONSTANCES), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Epidemiology and Data Science, APH - Aging & Later Life, APH - Societal Participation & Health, Public and occupational health, APH - Health Behaviors & Chronic Diseases, VU University medical center, APH - Personalized Medicine, Psychiatry, APH - Mental Health, Bin Zhou, Rodrigo M Carrillo-Larco, Goodarz Danaei, Leanne M Riley, Christopher J Paciorek, Gretchen A Stevens, Edward W Gregg, James E Bennett, Bethlehem Solomon, Rosie K Singleton, Marisa K Sophiea, Maria Lc Iurilli, Victor Pf Lhoste, Melanie J Cowan, Stefan Savin, Mark Woodward, Yulia Balanova, Renata Cifkova, Albertino Damasceno, Paul Elliott, Farshad Farzadfar, Jiang He, Nayu Ikeda, Andre P Kengne, Young-Ho Khang, Hyeon Chang Kim, Avula Laxmaiah, Hsien-Ho Lin, Paula Margozzini Maira, J Jaime Miranda, Hannelore Neuhauser, Johan Sundström, Cherian Varghese, Indah S Widyahening, Tomasz Zdrojewski, Leandra Abarca-Gómez, Ziad A Abdeen, Hanan F Abdul Rahim, Niveen M Abu-Rmeileh, Benjamin Acosta-Cazares, Robert J Adams, Wichai Aekplakorn, Kaosar Afsana, Shoaib Afzal, Imelda A Agdeppa, Javad Aghazadeh-Attari, Carlos A Aguilar-Salinas, Charles Agyemang, Noor Ani Ahmad, Ali Ahmadi, Naser Ahmadi, Nastaran Ahmadi, Fariba Ahmadizar, Soheir H Ahmed, Wolfgang Ahrens, Kamel Ajlouni, Rajaa Al-Raddadi, Monira Alarouj, Fadia AlBuhairan, Shahla AlDhukair, Mohamed M Ali, Abdullah Alkandari, Ala'a Alkerwi, Kristine Allin, Eman Aly, Deepak N Amarapurkar, Norbert Amougou, Philippe Amouyel, Lars Bo Andersen, Sigmund A Anderssen, Ranjit Mohan Anjana, Alireza Ansari-Moghaddam, Daniel Ansong, Hajer Aounallah-Skhiri, Joana Araújo, Inger Ariansen, Tahir Aris, Raphael E Arku, Nimmathota Arlappa, Krishna K Aryal, Thor Aspelund, Felix K Assah, Maria Cecília F Assunção, Juha Auvinen, Mária Avdićová, Ana Azevedo, Mohsen Azimi-Nezhad, Fereidoun Azizi, Mehrdad Azmin, Bontha V Babu, Suhad Bahijri, Nagalla Balakrishna, Mohamed Bamoshmoosh, Maciej Banach, Maja Banadinović, Piotr Bandosz, José R Banegas, Joanna Baran, Barbagallo Carlo Maria, Alberto Barceló, Amina Barkat, Marta Barreto, Aluisio Jd Barros, Mauro Virgílio Gomes Barros, Anna Bartosiewicz, Abdul Basit, Joao Luiz D Bastos, Iqbal Bata, Anwar M Batieha, Assembekov Batyrbek, Louise A Baur, Robert Beaglehole, Antonisamy Belavendra, Habiba Ben Romdhane, Mikhail Benet, Lowell S Benson, Salim Berkinbayev, Antonio Bernabe-Ortiz, Gailute Bernotiene, Heloísa Bettiol, Jorge Bezerra, Aroor Bhagyalaxmi, Santosh K Bhargava, Daniel Bia, Katia Biasch, Elysée Claude Bika Lele, Mukharram M Bikbov, Bihungum Bista, Peter Bjerregaard, Espen Bjertness, Marius B Bjertness, Cecilia Björkelund, Katia V Bloch, Anneke Blokstra, Simona Bo, Martin Bobak, Heiner Boeing, Jose G Boggia, Carlos P Boissonnet, Stig E Bojesen, Vanina Bongard, Alice Bonilla-Vargas, Matthias Bopp, Herman Borghs, Pascal Bovet, Christopher B Boyer, Lutgart Braeckman, Imperia Brajkovich, Francesco Branca, Juergen Breckenkamp, Hermann Brenner, Lizzy M Brewster, Yajaira Briceño, Miguel Brito, Graziella Bruno, H Bas Bueno-de-Mesquita, Gloria Bueno, Anna Bugge, Con Burns, Michael Bursztyn, Antonio Cabrera de León, Joseph Cacciottolo, Christine Cameron, Günay Can, Ana Paula C Cândido, Mario V Capanzana, Naděžda Čapková, Eduardo Capuano, Vincenzo Capuano, Viviane C Cardoso, Axel C Carlsson, Joana Carvalho, Felipe F Casanueva, Laura Censi, Marvin Cervantes-Loaiza, Charalambos A Chadjigeorgiou, Snehalatha Chamukuttan, Angelique W Chan, Queenie Chan, Himanshu K Chaturvedi, Nish Chaturvedi, Miao Li Chee, Chien-Jen Chen, Fangfang Chen, Huashuai Chen, Shuohua Chen, Zhengming Chen, Ching-Yu Cheng, Bahman Cheraghian, Imane Cherkaoui Dekkaki, Angela Chetrit, Kuo-Liong Chien, Arnaud Chiolero, Shu-Ti Chiou, Adela Chirita-Emandi, María-Dolores Chirlaque, Belong Cho, Kaare Christensen, Diego G Christofaro, Jerzy Chudek, Eliza Cinteza, Frank Claessens, Janine Clarke, Els Clays, Emmanuel Cohen, Hans Concin, Cyrus Cooper, Tara C Coppinger, Simona Costanzo, Dominique Cottel, Chris Cowell, Cora L Craig, Amelia C Crampin, Ana B Crujeiras, Juan J Cruz, Semánová Csilla, Liufu Cui, Felipe V Cureau, Sarah Cuschieri, Graziella D'Arrigo, Eleonora d'Orsi, Jean Dallongeville, Rachel Dankner, Thomas M Dantoft, Luc Dauchet, Kairat Davletov, Guy De Backer, Dirk De Bacquer, Amalia De Curtis, Giovanni de Gaetano, Stefaan De Henauw, Paula Duarte de Oliveira, David De Ridder, Delphine De Smedt, Mohan Deepa, Alexander D Deev, Vincent Jr DeGennaro, Hélène Delisle, Stefaan Demarest, Elaine Dennison, Valérie Deschamps, Meghnath Dhimal, Augusto F Di Castelnuovo, Juvenal Soares Dias-da-Costa, Alejandro Diaz, Ty T Dickerson, Zivka Dika, Shirin Djalalinia, Ha Tp Do, Annette J Dobson, Chiara Donfrancesco, Silvana P Donoso, Angela Döring, Maria Dorobantu, Marcus Dörr, Kouamelan Doua, Nico Dragano, Wojciech Drygas, Charmaine A Duante, Priscilla Duboz, Rosemary B Duda, Virginija Dulskiene, Anar Dushpanova, Aleksandar Džakula, Vilnis Dzerve, Elzbieta Dziankowska-Zaborszczyk, Ricky Eddie, Ebrahim Eftekhar, Robert Eggertsen, Sareh Eghtesad, Gabriele Eiben, Ulf Ekelund, Mohammad El-Khateeb, Jalila El Ati, Denise Eldemire-Shearer, Marie Eliasen, Roberto Elosua, Rajiv T Erasmus, Raimund Erbel, Cihangir Erem, Louise Eriksen, Johan G Eriksson, Jorge Escobedo-de la Peña, Saeid Eslami, Ali Esmaeili, Alun Evans, David Faeh, Albina A Fakhretdinova, Caroline H Fall, Elnaz Faramarzi, Mojtaba Farjam, Mohammad Reza Fattahi, Asher Fawwad, Francisco J Felix-Redondo, Stephan B Felix, Trevor S Ferguson, Romulo A Fernandes, Daniel Fernández-Bergés, Daniel Ferrante, Thomas Ferrao, Marika Ferrari, Marco M Ferrario, Catterina Ferreccio, Haroldo S Ferreira, Eldridge Ferrer, Jean Ferrieres, Thamara Hubler Figueiró, Günther Fink, Krista Fischer, Leng Huat Foo, Maria Forsner, Heba M Fouad, Damian K Francis, Maria do Carmo Franco, Ruth Frikke-Schmidt, Guillermo Frontera, Flavio D Fuchs, Sandra C Fuchs, Yuki Fujita, Matsuda Fumihiko, Viktoriya Furdela, Ariel Furer, Takuro Furusawa, Zbigniew Gaciong, Andrzej Galbarczyk, Henrike Galenkamp, Fabio Galvano, Jingli Gao, Pei Gao, Manoli Garcia-de-la-Hera, Pablo Garcia, Dickman Gareta, Sarah P Garnett, Jean-Michel Gaspoz, Magda Gasull, Andrea Gazzinelli, Ulrike Gehring, Johanna M Geleijnse, Ronnie George, Ali Ghanbari, Erfan Ghasemi, Oana-Florentina Gheorghe-Fronea, Anup Ghimire, Alessandro Gialluisi, Simona Giampaoli, Christian Gieger, Tiffany K Gill, Jonathan Giovannelli, Glen Gironella, Aleksander Giwercman, Konstantinos Gkiouras, Marcel Goldberg, Rebecca A Goldsmith, Luis F Gomez, Aleksandra Gomula, Helen Gonçalves, Mauer Gonçalves, Bruna Gonçalves Cordeiro da Silva, David A Gonzalez-Chica, Marcela Gonzalez-Gross, Juan P González-Rivas, Clicerio González-Villalpando, María-Elena González-Villalpando, Angel R Gonzalez, Mariano Bonet Gorbea, Frederic Gottrand, Sidsel Graff-Iversen, Dušan Grafnetter, Aneta Grajda, Maria G Grammatikopoulou, Ronald D Gregor, Tomasz Grodzicki, Giuseppe Grosso, Gabriella Gruden, Dongfeng Gu, Ong Peng Guan, Elias F Gudmundsson, Vilmundur Gudnason, Ramiro Guerrero, Idris Guessous, Andre L Guimaraes, Martin C Gulliford, Johanna Gunnlaugsdottir, Marc J Gunter, Prakash C Gupta, Rajeev Gupta, Oye Gureje, Beata Gurzkowska, Laura Gutierrez, Felix Gutzwiller, Seongjun Ha, Farzad Hadaegh, Rosa Haghshenas, Hamid Hakimi, Jytte Halkjær, Ian R Hambleton, Behrooz Hamzeh, Dominique Hange, Abu Am Hanif, Sari Hantunen, Jie Hao, Carla Menêses Hardman, Rachakulla Hari Kumar, Seyed Mohammad Hashemi-Shahri, Jun Hata, Teresa Haugsgjerd, Alison J Hayes, Yuna He, Margit Heier, Marleen Elisabeth Hendriks, Rafael Dos Santos Henrique, Ana Henriques, Leticia Hernandez Cadena, Herqutanto, Sauli Herrala, Ramin Heshmat, Allan G Hill, Sai Yin Ho, Suzanne C Ho, Michael Hobbs, Michelle Holdsworth, Reza Homayounfar, Gonul Horasan Dinc, Andrea Rvr Horimoto, Claudia M Hormiga, Bernardo L Horta, Leila Houti, Christina Howitt, Thein Thein Htay, Aung Soe Htet, Maung Maung Than Htike, Yonghua Hu, José María Huerta, Ilpo Tapani Huhtaniemi, Laetitia Huiart, Martijn Huisman, Abdullatif S Husseini, Inge Huybrechts, Nahla Hwalla, Licia Iacoviello, Anna G Iannone, Mohsen M Ibrahim, Norazizah Ibrahim Wong, M Arfan Ikram, Violeta Iotova, Vilma E Irazola, Takafumi Ishida, Godsent C Isiguzo, Muhammad Islam, Sheikh Mohammed Shariful Islam, Masanori Iwasaki, Rod T Jackson, Jeremy M Jacobs, Hashem Y Jaddou, Tazeen Jafar, Kenneth James, Konrad Jamrozik, Imre Janszky, Edward Janus, Marjo-Riitta Jarvelin, Grazyna Jasienska, Ana Jelaković, Bojan Jelaković, Garry Jennings, Anjani Kumar Jha, Chao Qiang Jiang, Ramon O Jimenez, Karl-Heinz Jöckel, Michel Joffres, Mattias Johansson, Jari J Jokelainen, Jost B Jonas, Torben Jørgensen, Pradeep Joshi, Farahnaz Joukar, Jacek Jóżwiak, Anne Juolevi, Gregor Jurak, Vesna Jureša, Rudolf Kaaks, Anthony Kafatos, Eero O Kajantie, Zhanna Kalmatayeva, Natasa Kalpourtzi, Ofra Kalter-Leibovici, Freja B Kampmann, Srinivasan Kannan, Eva Karaglani, Line L Kårhus, Khem B Karki, Marzieh Katibeh, Joanne Katz, Jussi Kauhanen, Prabhdeep Kaur, Maryam Kavousi, Gyulli M Kazakbaeva, Ulrich Keil, Lital Keinan Boker, Sirkka Keinänen-Kiukaanniemi, Roya Kelishadi, Han Cg Kemper, Maryam Keramati, Alina Kerimkulova, Mathilde Kersting, Timothy Key, Yousef Saleh Khader, Davood Khalili, Kay-Tee Khaw, Bahareh Kheiri, Motahareh Kheradmand, Alireza Khosravi, Ursula Kiechl-Kohlendorfer, Stefan Kiechl, Japhet Killewo, Dong Wook Kim, Jeongseon Kim, Heidi Klakk, Magdalena Klimek, Jurate Klumbiene, Michael Knoflach, Elin Kolle, Patrick Kolsteren, Jukka P Kontto, Raija Korpelainen, Paul Korrovits, Jelena Kos, Seppo Koskinen, Katsuyasu Kouda, Sudhir Kowlessur, Slawomir Koziel, Jana Kratenova, Vilma Kriaucioniene, Peter Lund Kristensen, Steiner Krokstad, Daan Kromhout, Herculina S Kruger, Ruzena Kubinova, Renata Kuciene, Urho M Kujala, Zbigniew Kulaga, R Krishna Kumar, Pawel Kurjata, Yadlapalli S Kusuma, Vladimir Kutsenko, Kari Kuulasmaa, Catherine Kyobutungi, Tiina Laatikainen, Carl Lachat, Youcef Laid, Tai Hing Lam, Orlando Landrove, Vera Lanska, Georg Lappas, Bagher Larijani, Tint Swe Latt, Gwenaëlle Le Coroller, Khanh Le Nguyen Bao, Tuyen D Le, Jeannette Lee, Jeonghee Lee, Nils Lehmann, Terho Lehtimäki, Daniel Lemogoum, Naomi S Levitt, Yanping Li, Christa L Lilly, Wei-Yen Lim, M Fernanda Lima-Costa, Xu Lin, Yi-Ting Lin, Lars Lind, Vijaya Lingam, Allan Linneberg, Lauren Lissner, Mieczyslaw Litwin, Wei-Cheng Lo, Helle-Mai Loit, Esther Lopez-Garcia, Tania Lopez, Paulo A Lotufo, José Eugenio Lozano, Iva Lukačević Lovrenčić, Janice L Lukrafka, Dalia Luksiene, Annamari Lundqvist, Robert Lundqvist, Nuno Lunet, Michala Lustigová, Edyta Luszczki, Guansheng Ma, Jun Ma, George Ll Machado-Coelho, Aristides M Machado-Rodrigues, Enguerran Macia, Luisa M Macieira, Ahmed A Madar, Stefania Maggi, Dianna J Magliano, Emmanuella Magriplis, Gowri Mahasampath, Bernard Maire, Marjeta Majer, Marcia Makdisse, Fatemeh Malekzadeh, Reza Malekzadeh, Rahul Malhotra, Kodavanti Mallikharjuna Rao, Sofia K Malyutina, Lynell V Maniego, Yannis Manios, Jim I Mann, Fariborz Mansour-Ghanaei, Enzo Manzato, Anie Marcil, Staffan B Mårild, Mihalea Marinović Glavić, Pedro Marques-Vidal, Larissa Pruner Marques, Jaume Marrugat, Reynaldo Martorell, Luis P Mascarenhas, Marija Matasin, Ellisiv B Mathiesen, Prashant Mathur, Alicia Matijasevich, Piotr Matlosz, Tandi E Matsha, Christina Mavrogianni, Jean Claude N Mbanya, Anselmo J Mc Donald Posso, Shelly R McFarlane, Stephen T McGarvey, Stela McLachlan, Rachael M McLean, Scott B McLean, Breige A McNulty, Sounnia Mediene Benchekor, Jurate Medzioniene, Parinaz Mehdipour, Kirsten Mehlig, Amir Houshang Mehrparvar, Aline Meirhaeghe, Christa Meisinger, Carlos Mendoza Montano, Ana Maria B Menezes, Geetha R Menon, Alibek Mereke, Indrapal I Meshram, Andres Metspalu, Haakon E Meyer, Jie Mi, Nathalie Michels, Kairit Mikkel, Karolina Milkowska, Jody C Miller, Cláudia S Minderico, G K Mini, Mohammad Reza Mirjalili, Erkin Mirrakhimov, Marjeta Mišigoj-Duraković, Pietro A Modesti, Sahar Saeedi Moghaddam, Bahram Mohajer, Mostafa K Mohamed, Shukri F Mohamed, Kazem Mohammad, Mohammad Reza Mohammadi, Zahra Mohammadi, Noushin Mohammadifard, Reza Mohammadpourhodki, Viswanathan Mohan, Salim Mohanna, Muhammad Fadhli Mohd Yusoff, Iraj Mohebbi, Farnam Mohebi, Marie Moitry, Line T Møllehave, Dénes Molnár, Amirabbas Momenan, Charles K Mondo, Eric Monterrubio-Flores, Kotsedi Daniel K Monyeki, Jin Soo Moon, Mahmood Moosazadeh, Leila B Moreira, Alain Morejon, Luis A Moreno, Karen Morgan, George Moschonis, Malgorzata Mossakowska, Aya Mostafa, Seyed-Ali Mostafavi, Jorge Mota, Mohammad Esmaeel Motlagh, Jorge Motta, Marcos André Moura-Dos-Santos, Malay K Mridha, Kelias P Msyamboza, Thet Thet Mu, Alfa J Muhihi, Maria L Muiesan, Martina Müller-Nurasyid, Neil Murphy, Jaakko Mursu, Kamarul Imran Musa, Sanja Musić Milanović, Vera Musil, Norlaila Mustafa, Iraj Nabipour, Shohreh Naderimagham, Gabriele Nagel, Balkish M Naidu, Farid Najafi, Harunobu Nakamura, Jana Námešná, Ei Ei K Nang, Vinay B Nangia, Sameer Narake, Ndeye Coumba Ndiaye, William A Neal, Azim Nejatizadeh, Ilona Nenko, Martin Neovius, Chung T Nguyen, Nguyen D Nguyen, Quang V Nguyen, Quang Ngoc Nguyen, Ramfis E Nieto-Martínez, Teemu J Niiranen, Yury P Nikitin, Toshiharu Ninomiya, Sania Nishtar, Marina A Njelekela, Marianna Noale, Oscar A Noboa, Ahmad Ali Noorbala, Teresa Norat, Maria Nordendahl, Børge G Nordestgaard, Noto Davide, Natalia Nowak-Szczepanska, Mohannad Al Nsour, Baltazar Nunes, Terence W O'Neill, Dermot O'Reilly, Caleb Ochimana, Eiji Oda, Augustine N Odili, Kyungwon Oh, Kumiko Ohara, Ryutaro Ohtsuka, Valérie Olié, Maria Teresa A Olinto, Isabel O Oliveira, Mohd Azahadi Omar, Altan Onat, Sok King Ong, Lariane M Ono, Pedro Ordunez, Rui Ornelas, Pedro J Ortiz, Clive Osmond, Sergej M Ostojic, Afshin Ostovar, Johanna A Otero, Kim Overvad, Ellis Owusu-Dabo, Fred Michel Paccaud, Cristina Padez, Elena Pahomova, Karina Mary de Paiva, Andrzej Pająk, Domenico Palli, Luigi Palmieri, Wen-Harn Pan, Songhomitra Panda-Jonas, Francesco Panza, Mariela Paoli, Dimitrios Papandreou, Soon-Woo Park, Suyeon Park, Winsome R Parnell, Mahboubeh Parsaeian, Patrick Pasquet, Nikhil D Patel, Halyna Pavlyshyn, Ivan Pećin, Mangesh S Pednekar, João M Pedro, Nasheeta Peer, Sergio Viana Peixoto, Markku Peltonen, Alexandre C Pereira, Karen Gda Peres, Marco A Peres, Annette Peters, Janina Petkeviciene, Niloofar Peykari, Son Thai Pham, Rafael N Pichardo, Iris Pigeot, Hynek Pikhart, Aida Pilav, Lorenza Pilotto, Freda Pitakaka, Aleksandra Piwonska, Andreia N Pizarro, Pedro Plans-Rubió, Ozren Polašek, Miquel Porta, Anil Poudyal, Farhad Pourfarzi, Akram Pourshams, Hossein Poustchi, Rajendra Pradeepa, Alison J Price, Jacqueline F Price, Rui Providencia, Soile E Puhakka, Maria Puiu, Margus Punab, Radwan F Qasrawi, Mostafa Qorbani, Daniel Queiroz, Tran Quoc Bao, Ivana Radić, Ricardas Radisauskas, Salar Rahimikazerooni, Mahfuzar Rahman, Olli Raitakari, Manu Raj, Ellina M Rakhimova, Sudha Ramachandra Rao, Ambady Ramachandran, Elisabete Ramos, Lekhraj Rampal, Sanjay Rampal, Daniel A Rangel Reina, Vayia Rarra, Cassiano Ricardo Rech, Josep Redon, Paul Ferdinand M Reganit, Valéria Regecová, Luis Revilla, Abbas Rezaianzadeh, Robespierre Ribeiro, Elio Riboli, Adrian Richter, Fernando Rigo, Tobias F Rinke de Wit, Raphael M Ritti-Dias, Cynthia Robitaille, Fernando Rodríguez-Artalejo, María Del Cristo Rodriguez-Perez, Laura A Rodríguez-Villamizar, Ulla Roggenbuck, Rosalba Rojas-Martinez, Dora Romaguera, Elisabetta L Romeo, Annika Rosengren, Joel Gr Roy, Adolfo Rubinstein, Jean-Bernard Ruidavets, Blanca Sandra Ruiz-Betancourt, Maria Ruiz-Castell, Iuliia A Rusakova, Paola Russo, Marcin Rutkowski, Charumathi Sabanayagam, Hamideh Sabbaghi, Harshpal S Sachdev, Alireza Sadjadi, Ali Reza Safarpour, Sare Safi, Saeid Safiri, Olfa Saidi, Sibel Sakarya, Nader Saki, Benoit Salanave, Eduardo Salazar Martinez, Diego Salmerón, Veikko Salomaa, Jukka T Salonen, Massimo Salvetti, Jose Sánchez-Abanto, Susana Sans, Diana A Santos, Ina S Santos, Lèlita C Santos, Maria Paula Santos, Rute Santos, Jouko L Saramies, Luis B Sardinha, Giselle Sarganas, Nizal Sarrafzadegan, Thirunavukkarasu Sathish, Kai-Uwe Saum, Savvas Savva, Norie Sawada, Mariana Sbaraini, Marcia Scazufca, Beatriz D Schaan, Herman Schargrodsky, Sabine Schipf, Carsten O Schmidt, Peter Schnohr, Ben Schöttker, Sara Schramm, Constance Schultsz, Aletta E Schutte, Sylvain Sebert, Aye Aye Sein, Abhijit Sen, Idowu O Senbanjo, Sadaf G Sepanlou, Jennifer Servais, Svetlana A Shalnova, Teresa Shamah-Levy, Morteza Shamshirgaran, Coimbatore Subramaniam Shanthirani, Maryam Sharafkhah, Sanjib K Sharma, Jonathan E Shaw, Amaneh Shayanrad, Ali Akbar Shayesteh, Zumin Shi, Kenji Shibuya, Hana Shimizu-Furusawa, Dong Wook Shin, Majid Shirani, Rahman Shiri, Namuna Shrestha, Khairil Si-Ramlee, Alfonso Siani, Rosalynn Siantar, Abla M Sibai, Caroline Ramos de Moura Silva, Diego Augusto Santos Silva, Mary Simon, Judith Simons, Leon A Simons, Michael Sjöström, Jolanta Slowikowska-Hilczer, Przemyslaw Slusarczyk, Liam Smeeth, Hung-Kwan So, Fernanda Cunha Soares, Eugène Sobngwi, Stefan Söderberg, Agustinus Soemantri, Reecha Sofat, Vincenzo Solfrizzi, Mohammad Hossein Somi, Emily Sonestedt, Yi Song, Thorkild Ia Sørensen, Elin P Sørgjerd, Maroje Sorić, Charles Sossa Jérome, Aïcha Soumaré, Bente Sparboe-Nilsen, Karen Sparrenberger, Jan A Staessen, Gregor Starc, Bill Stavreski, Jostein Steene-Johannessen, Peter Stehle, Aryeh D Stein, George S Stergiou, Jochanan Stessman, Jutta Stieber, Doris Stöckl, Tanja Stocks, Jakub Stokwiszewski, Karien Stronks, Maria Wany Strufaldi, Machi Suka, Chien-An Sun, Yn-Tz Sung, Paibul Suriyawongpaisal, Rody G Sy, Holly E Syddall, René Charles Sylva, Moyses Szklo, E Shyong Tai, Mari-Liis Tammesoo, Abdonas Tamosiunas, Eng Joo Tan, Xun Tang, Frank Tanser, Yong Tao, Mohammed Rasoul Tarawneh, Carolina B Tarqui-Mamani, Anne Taylor, Julie Taylor, William R Tebar, Grethe S Tell, Tania Tello, Yih Chung Tham, K R Thankappan, Holger Theobald, Xenophon Theodoridis, Lutgarde Thijs, Mikael Thinggaard, Nihal Thomas, Barbara Thorand, Betina H Thuesen, Erik J Timmermans, Dwi H Tjandrarini, Anne Tjonneland, Ulla Toft, Hanna K Tolonen, Janne S Tolstrup, Murat Topbas, Roman Topór-Madry, María José Tormo, Michael J Tornaritis, Maties Torrent, Laura Torres-Collado, Giota Touloumi, Pierre Traissac, Areti Triantafyllou, Dimitrios Trichopoulos, Antonia Trichopoulou, Oanh Th Trinh, Atul Trivedi, Lechaba Tshepo, Shoichiro Tsugane, Azaliia M Tuliakova, Marshall K Tulloch-Reid, Fikru Tullu, Tomi-Pekka Tuomainen, Jaakko Tuomilehto, Maria L Turley, Gilad Twig, Per Tynelius, Christophe Tzourio, Peter Ueda, Eunice Ugel, Hanno Ulmer, Hannu Mt Uusitalo, Gonzalo Valdivia, Damaskini Valvi, Rob M van Dam, Bert-Jan van den Born, Johan Van der Heyden, Yvonne T van der Schouw, Koen Van Herck, Hoang Van Minh, Natasja M Van Schoor, Irene Gm van Valkengoed, Elisabeth M van Zutphen, Dirk Vanderschueren, Diego Vanuzzo, Anette Varbo, Senthil K Vasan, Tomas Vega, Toomas Veidebaum, Gustavo Velasquez-Melendez, Giovanni Veronesi, Wm Monique Verschuren, Roosmarijn Verstraeten, Cesar G Victora, Lucie Viet, Salvador Villalpando, Paolo Vineis, Jesus Vioque, Jyrki K Virtanen, Sophie Visvikis-Siest, Bharathi Viswanathan, Tiina Vlasoff, Peter Vollenweider, Ari Voutilainen, Alisha N Wade, Janette Walton, Elvis Oa Wambiya, Wan Mohamad Wan Bebakar, Wan Nazaimoon Wan Mohamud, Rildo de Souza Wanderley Júnior, Ming-Dong Wang, Ningli Wang, Qian Wang, Xiangjun Wang, Ya Xing Wang, Ying-Wei Wang, S Goya Wannamethee, Nicholas Wareham, Wenbin Wei, Aneta Weres, Bo Werner, Peter H Whincup, Kurt Widhalm, Andrzej Wiecek, Rainford J Wilks, Johann Willeit, Peter Willeit, Emmanuel A Williams, Tom Wilsgaard, Bogdan Wojtyniak, Roy A Wong-McClure, Andrew Wong, Tien Yin Wong, Jean Woo, Frederick C Wu, Shouling Wu, Justyna Wyszynska, Haiquan Xu, Liang Xu, Nor Azwany Yaacob, Weili Yan, Ling Yang, Xiaoguang Yang, Yang Yang, Tabara Yasuharu, Xingwang Ye, Panayiotis K Yiallouros, Moein Yoosefi, Akihiro Yoshihara, San-Lin You, Novie O Younger-Coleman, Ahmad Faudzi Yusoff, Ahmad A Zainuddin, Seyed Rasoul Zakavi, Farhad Zamani, Sabina Zambon, Antonis Zampelas, Maria Elisa Zapata, Ko Ko Zaw, Kristyna Zejglicova, Tajana Zeljkovic Vrkic, Yi Zeng, Luxia Zhang, Zhen-Yu Zhang, Dong Zhao, Ming-Hui Zhao, Shiqi Zhen, Yingfeng Zheng, Bekbolat Zholdin, Dan Zhu, Marie Zins, Emanuel Zitt, Yanina Zocalo, Nada Zoghlami, Julio Zuñiga Cisneros, Majid Ezzati, Sakarya, Sibel (ORCID 0000-0002-9959-6240 & YÖK ID 172028), Zhou, Bin, Carrillo-Larco, Rodrigo M., Danaei, Goodarz, Riley, Leanne M., Paciorek, Christopher J., Stevens, Gretchen A., Gregg, Edward W., Bennett, James E., Solomon, Bethlehem, Singleton, Rosie K., Sophiea, Marisa K., Iurilli, Maria L. C., Lhoste, Victor P. F., Cowan, Melanie J., Savin, Stefan, Woodward, Mark, Balanova, Yulia, Cifkova, Renata, Damasceno, Albertino, Elliott, Paul, Farzadfar, Farshad, He, Jiang, Ikeda, Nayu, Kengne, Andre P., Khang, Young-Ho, Kim, Hyeon Chang, Laxmaiah, Avula, Lin, Hsien-Ho, Margozzini Maira, Paula, Miranda, J. Jaime, Neuhauser, Hannelore, Sundstrom, Johan, Varghese, Cherian, Widyahening, Indah S., Zdrojewski, Tomasz, Ezzati, Majid, Abarca-Gomez, Leandra, Abdeen, Ziad A., Rahim, Hanan F. Abdul, Abu-Rmeileh, Niveen M., Acosta-Cazares, Benjamin, Adams, Robert J., Aekplakorn, Wichai, Afsana, Kaosar, Afzal, Shoaib, Agdeppa, Imelda A., Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A., Agyemang, Charles, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmadizar, Fariba, Ahmed, Soheir H., Ahrens, Wolfgang, Ajlouni, Kamel, Al-Raddadi, Rajaa, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M., Alkandari, Abdullah, Alkerwi, Ala'a, Allin, Kristine, Aly, Eman, Amarapurkar, Deepak N., Amougou, Norbert, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A., Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Ansong, Daniel, Aounallah-Skhiri, Hajer, Araujo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E., Arlappa, Nimmathota, Aryal, Krishna K., Aspelund, Thor, Assah, Felix K., Assuncao, Maria Cecilia F., Auvinen, Juha, Avdicova, Maria, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha V., Bahijri, Suhad, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Banadinovic, Maja, Bandosz, Piotr, Banegas, Jose R., Baran, Joanna, Barbagallo, Carlo M., Barcelo, Alberto, Barkat, Amina, Barreto, Marta, Barros, Aluisio J. D., Gomes Barros, Mauro Virgilio, Bartosiewicz, Anna, Basit, Abdul, Bastos, Joao Luiz D., Bata, Iqbal, Batieha, Anwar M., Batyrbek, Assembekov, Baur, Louise A., Beaglehole, Robert, Belavendra, Antonisamy, Ben Romdhane, Habiba, Benet, Mikhail, Benson, Lowell S., Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bettiol, Heloisa, Bezerra, Jorge, Bhagyalaxmi, Aroor, Bhargava, Santosh K., Bia, Daniel, Biasch, Katia, Lele, Elysee Claude Bika, Bikbov, Mukharram M., Bista, Bihungum, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B., Bjorkelund, Cecilia, Bloch, Katia V., Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boeing, Heiner, Boggia, Jose G., Boissonnet, Carlos P., Bojesen, Stig E., Bongard, Vanina, Bonilla-Vargas, Alice, Bopp, Matthias, Bovet, Pascal, Boyer, Christopher B., Braeckman, Lutgart, Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Brenner, Hermann, Brewster, Lizzy M., Briceno, Yajaira, Brito, Miguel, Bruno, Graziella, Bueno-de-Mesquita, H. Bas, Bueno, Gloria, Bugge, Anna, Burns, Con, Bursztyn, Michael, Cabrera de Leon, Antonio, Cacciottolo, Joseph, Cameron, Christine, Can, Gunay, Candido, Ana Paula C., Capanzana, Mario V., Capkova, Nadezda, Capuano, Eduardo, Capuano, Vincenzo, Cardoso, Viviane C., Carlsson, Axel C., Carvalho, Joana, Casanueva, Felipe F., Censi, Laura, Cervantes-Loaiza, Marvin, Chadjigeorgiou, Charalambos A., Chamukuttan, Snehalatha, Chan, Angelique W., Chan, Queenie, Chaturvedi, Himanshu K., Chaturvedi, Nish, Chee, Miao Li, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Cheraghian, Bahman, Dekkaki, Imane Cherkaoui, Chetrit, Angela, Chien, Kuo-Liong, Chiolero, Arnaud, Chiou, Shu-Ti, Chirita-Emandi, Adela, Chirlaque, Maria-Dolores, Cho, Belong, Christensen, Kaare, Christofaro, Diego G., Chudek, Jerzy, Cinteza, Eliza, Clarke, Janine, Clays, Els, Cohen, Emmanuel, Concin, Hans, Cooper, Cyrus, Coppinger, Tara C., Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Craig, Cora L., Crampin, Amelia C., Crujeiras, Ana B., Cruz, Juan J., Csilla, Semanova, Cui, Liufu, Cureau, Felipe V., Cuschieri, Sarah, D'Arrigo, Graziella, d'Orsi, Eleonora, Dallongeville, Jean, Dankner, Rachel, Dantoft, Thomas M., Dauchet, Luc, Davletov, Kairat, De Backer, Guy, De Bacquer, Dirk, De Curtis, Amalia, de Gaetano, Giovanni, De Henauw, Stefaan, de Oliveira, Paula Duarte, De Ridder, David, De Smedt, Delphine, Deepa, Mohan, Deev, Alexander D., DeGennaro, Vincent Jr, Delisle, Helene, Demarest, Stefaan, Dennison, Elaine, Deschamps, Valerie, Dhimal, Meghnath, Di Castelnuovo, Augusto F., Dias-da-Costa, Juvenal Soares, Diaz, Alejandro, Dickerson, Ty T., Dika, Zivka, Djalalinia, Shirin, Do, Ha T. P., Dobson, Annette J., Donfrancesco, Chiara, Donoso, Silvana P., Doering, Angela, Dorobantu, Maria, Doerr, Marcus, Doua, Kouamelan, Dragano, Nico, Drygas, Wojciech, Duante, Charmaine A., Duboz, Priscilla, Duda, Rosemary B., Dulskiene, Virginija, Dushpanova, Anar, Dzakula, Aleksandar, Dzerve, Vilnis, Dziankowska-Zaborszczyk, Elzbieta, Eddie, Ricky, Eftekhar, Ebrahim, Eggertsen, Robert, Eghtesad, Sareh, Eiben, Gabriele, Ekelund, Ulf, El-Khateeb, Mohammad, El Ati, Jalila, Eldemire-Shearer, Denise, Eliasen, Marie, Elosua, Roberto, Erasmus, Rajiv T., Erbel, Raimund, Erem, Cihangir, Eriksen, Louise, Eriksson, Johan G., Escobedo-de la Pena, Jorge, Eslami, Saeid, Esmaeili, Ali, Evans, Alun, Faeh, David, Fakhretdinova, Albina A., Fall, Caroline H., Faramarzi, Elnaz, Farjam, Mojtaba, Fattahi, Mohammad Reza, Fawwad, Asher, Felix-Redondo, Francisco J., Felix, Stephan B., Ferguson, Trevor S., Fernandes, Romulo A., Fernandez-Berges, Daniel, Ferrante, Daniel, Ferrao, Thomas, Ferrari, Marika, Ferrario, Marco M., Ferreccio, Catterina, Ferreira, Haroldo S., Ferrer, Eldridge, Ferrieres, Jean, Figueiro, Thamara Hubler, Fink, Gunther, Fischer, Krista, Foo, Leng Huat, Forsner, Maria, Fouad, Heba M., Francis, Damian K., Franco, Maria do Carmo, Frikke-Schmidt, Ruth, Frontera, Guillermo, Fuchs, Flavio D., Fuchs, Sandra C., Fujita, Yuki, Fumihiko, Matsuda, Furdela, Viktoriya, Furer, Ariel, Furusawa, Takuro, Gaciong, Zbigniew, Galbarczyk, Andrzej, Galenkamp, Henrike, Galvano, Fabio, Gao, Jingli, Gao, Pei, Garcia-de-la-Hera, Manoli, Garcia, Pablo, Gareta, Dickman, Garnett, Sarah P., Gaspoz, Jean-Michel, Gasull, Magda, Gazzinelli, Andrea, Gehring, Ulrike, Geleijnse, Johanna M., George, Ronnie, Ghanbari, Ali, Ghasemi, Erfan, Gheorghe-Fronea, Oana-Florentina, Ghimire, Anup, Gialluisi, Alessandro, Giampaoli, Simona, Gieger, Christian, Gill, Tiffany K., Giovannelli, Jonathan, Gironella, Glen, Giwercman, Aleksander, Gkiouras, Konstantinos, Goldberg, Marcel, Goldsmith, Rebecca A., Gomez, Luis F., Gomula, Aleksandra, Cordeiro da Silva, Bruna Goncalves, Goncalves, Helen, Goncalves, Mauer, Gonzalez-Chica, David A., Gonzalez-Gross, Marcela, Gonzalez-Rivas, Juan P., Gonzalez-Villalpando, Clicerio, Gonzalez-Villalpando, Maria-Elena, Gonzalez, Angel R., Bonet Gorbea, Mariano, Gottrand, Frederic, Graff-Iversen, Sidsel, Grafnetter, Dusan, Grajda, Aneta, Grammatikopoulou, Maria G., Gregor, Ronald D., Grodzicki, Tomasz, Grosso, Giuseppe, Gruden, Gabriella, Gu, Dongfeng, Guan, Ong Peng, Gudmundsson, Elias F., Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idris, Guimaraes, Andre L., Gulliford, Martin C., Gunnlaugsdottir, Johanna, Gunter, Marc J., Gupta, Prakash C., Gupta, Rajeev, Gureje, Oye, Gurzkowska, Beata, Gutierrez, Laura, Gutzwiller, Felix, Ha, Seongjun, Hadaegh, Farzad, Haghshenas, Rosa, Hakimi, Hamid, Halkjaer, Jytte, Hambleton, Ian R., Hamzeh, Behrooz, Hange, Dominique, Hanif, Abu A. M., Hantunen, Sari, Hao, Jie, Hardman, Carla Meneses, Kumar, Rachakulla Hari, Hashemi-Shahri, Seyed Mohammad, Hata, Jun, Haugsgjerd, Teresa, Hayes, Alison J., He, Yuna, Heier, Margit, Hendriks, Marleen Elisabeth, Henrique, Rafael dos Santos, Henriques, Ana, Cadena, Leticia Hernandez, Herrala, Sauli, Heshmat, Ramin, Hill, Allan G., Ho, Sai Yin, Ho, Suzanne C., Hobbs, Michael, Holdsworth, Michelle, Homayounfar, Reza, Dinc, Gonul Horasan, Horimoto, Andrea R. V. R., Hormiga, Claudia M., Horta, Bernardo L., Houti, Leila, Howitt, Christina, Htay, Thein Thein, Htet, Aung Soe, Htike, Maung Maung Than, Hu, Yonghua, Huerta, Jose Maria, Huhtaniemi, Ilpo Tapani, Huiart, Laetitia, Huisman, Martijn, Husseini, Abdullatif S., Huybrechts, Inge, Hwalla, Nahla, Iacoviello, Licia, Iannone, Anna G., Ibrahim, Mohsen M., Wong, Norazizah Ibrahim, Ikram, M. Arfan, Iotova, Violeta, Irazola, Vilma E., Ishida, Takafumi, Isiguzo, Godsent C., Islam, Muhammad, Islam, Sheikh Mohammed Shariful, Iwasaki, Masanori, Jackson, Rod T., Jacobs, Jeremy M., Jaddou, Hashem Y., Jafar, Tazeen, James, Kenneth, Jamrozik, Konrad, Janszky, Imre, Janus, Edward, Jarvelin, Marjo-Riitta, Jasienska, Grazyna, Jelakovic, Ana, Jelakovic, Bojan, Jennings, Garry, Jha, Anjani Kumar, Jiang, Chao Qiang, Jimenez, Ramon O., Joeckel, Karl-Heinz, Joffres, Michel, Johansson, Mattias, Jokelainen, Jari J., Jonas, Jost B., Jorgensen, Torben, Joshi, Pradeep, Joukar, Farahnaz, Jozwiak, Jacek, Juolevi, Anne, Jurak, Gregor, Juresa, Vesna, Kaaks, Rudolf, Kafatos, Anthony, Kajantie, Eero O., Kalmatayeva, Zhanna, Kalpourtzi, Natasa, Kalter-Leibovici, Ofra, Kampmann, Freja B., Kannan, Srinivasan, Karaglani, Eva, Karhus, Line L., Karki, Khem B., Katibeh, Marzieh, Katz, Joanne, Kauhanen, Jussi, Kaur, Prabhdeep, Kavousi, Maryam, Kazakbaeva, Gyulli M., Keil, Ulrich, Boker, Lital Keinan, Keinanen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kemper, Han C. G., Keramati, Maryam, Kerimkulova, Alina, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khalili, Davood, Khaw, Kay-Tee, Kheiri, Bahareh, Kheradmand, Motahareh, Khosravi, Alireza, Kiechl-Kohlendorfer, Ursula, Kiechl, Stefan, Killewo, Japhet, Kim, Dong Wook, Kim, Jeongseon, Klakk, Heidi, Klimek, Magdalena, Klumbiene, Jurate, Knoflach, Michael, Kolle, Elin, Kolsteren, Patrick, Kontto, Jukka P., Korpelainen, Raija, Korrovits, Paul, Kos, Jelena, Koskinen, Seppo, Kouda, Katsuyasu, Kowlessur, Sudhir, Koziel, Slawomir, Kratenova, Jana, Kriaucioniene, Vilma, Kristensen, Peter Lund, Krokstad, Steiner, Kromhout, Daan, Kruger, Herculina S., Kubinova, Ruzena, Kuciene, Renata, Kujala, Urho M., Kulaga, Zbigniew, Kumar, R. Krishna, Kurjata, Pawel, Kusuma, Yadlapalli S., Kutsenko, Vladimir, Kuulasmaa, Kari, Kyobutungi, Catherine, Laatikainen, Tiina, Lachat, Carl, Laid, Youcef, Lam, Tai Hing, Landrove, Orlando, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Latt, Tint Swe, Le Coroller, Gwenaelle, Khanh Le Nguyen Bao, Le, Tuyen D., Lee, Jeannette, Lee, Jeonghee, Lehmann, Nils, Lehtimaki, Terho, Lemogoum, Daniel, Levitt, Naomi S., Li, Yanping, Lilly, Christa L., Lim, Wei-Yen, Lima-Costa, M. Fernanda, Lin, Xu, Lin, Yi-Ting, Lind, Lars, Lingam, Vijaya, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Lo, Wei-Cheng, Loit, Helle-Mai, Lopez-Garcia, Esther, Lopez, Tania, Lotufo, Paulo A., Lozano, Jose Eugenio, Lovrencic, Iva Lukacevic, Lukrafka, Janice L., Luksiene, Dalia, Lundqvist, Annamari, Lundqvist, Robert, Lunet, Nuno, Lustigova, Michala, Luszczki, Edyta, Ma, Guansheng, Ma, Jun, Machado-Coelho, George L. L., Machado-Rodrigues, Aristides M., Macia, Enguerran, Macieira, Luisa M., Madar, Ahmed A., Maggi, Stefania, Magliano, Dianna J., Magriplis, Emmanuella, Mahasampath, Gowri, Maire, Bernard, Majer, Marjeta, Makdisse, Marcia, Malekzadeh, Fatemeh, Malekzadeh, Reza, Malhotra, Rahul, Mallikharjuna, Kodavanti, Malyutina, Sofia K., Maniego, Lynell V., Manios, Yannis, Mann, Jim I., Mansour-Ghanaei, Fariborz, Manzato, Enzo, Marcil, Anie, Margozzini, Paula, Marild, Staffan B., Glavic, Mihalea Marinovic, Marques-Vidal, Pedro, Marques, Larissa Pruner, Marrugat, Jaume, Martorell, Reynaldo, Mascarenhas, Luis P., Matasin, Marija, Mathiesen, Ellisiv B., Mathur, Prashant, Matijasevich, Alicia, Matlosz, Piotr, Matsha, Tandi E., Mavrogianni, Christina, Mbanya, Jean Claude N., Mc Donald Posso, Anselmo J., McFarlane, Shelly R., McGarvey, Stephen T., McLachlan, Stela, McLean, Rachael M., McLean, Scott B., McNulty, Breige A., Benchekor, Sounnia Mediene, Medzioniene, Jurate, Mehdipour, Parinaz, Mehlig, Kirsten, Mehrparvar, Amir Houshang, Meirhaeghe, Aline, Meisinger, Christa, Mendoza Montano, Carlos, Menezes, Ana Maria B., Menon, Geetha R., Mereke, Alibek, Meshram, Indrapal I., Metspalu, Andres, Meyer, Haakon E., Mi, Jie, Michels, Nathalie, Mikkel, Kairit, Milkowska, Karolina, Miller, Jody C., Minderico, Claudia S., Mini, G. K., Mirjalili, Mohammad Reza, Mirrakhimov, Erkin, Misigoj-Durakovic, Marjeta, Modesti, Pietro A., Moghaddam, Sahar Saeedi, Mohajer, Bahram, Mohamed, Mostafa K., Mohamed, Shukri F., Mohammad, Kazem, Mohammadi, Mohammad Reza, Mohammadi, Zahra, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohan, Viswanathan, Mohanna, Salim, Yusoff, Muhammad Fadhli Mohd, Mohebbi, Iraj, Mohebi, Farnam, Moitry, Marie, Mollehave, Line T., Molnar, Denes, Momenan, Amirabbas, Mondo, Charles K., Monterrubio-Flores, Eric, Monyeki, Kotsedi Daniel K., Moon, Jin Soo, Moosazadeh, Mahmood, Moreira, Leila B., Morejon, Alain, Moreno, Luis A., Morgan, Karen, Moschonis, George, Mossakowska, Malgorzata, Mostafa, Aya, Mostafavi, Seyed-Ali, Mota, Jorge, Motlagh, Mohammad Esmaeel, Motta, Jorge, Andre Moura-dos-Santos, Marcos, Mridha, Malay K., Msyamboza, Kelias P., Mu, Thet Thet, Muhihi, Alfa J., Muiesan, Maria L., Muller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Musa, Kamarul Imran, Milanovic, Sanja Music, Musil, Vera, Mustafa, Norlaila, Nabipour, Iraj, Naderimagham, Shohreh, Nagel, Gabriele, Naidu, Balkish M., Najafi, Farid, Nakamura, Harunobu, Namesna, Jana, Nang, Ei Ei K., Nangia, Vinay B., Narake, Sameer, Ndiaye, Ndeye Coumba, Neal, William A., Nejatizadeh, Azim, Nenko, Ilona, Neovius, Martin, Neuhauser, Hannelore K., Nguyen, Chung T., Nguyen, Nguyen D., Nguyen, Quang V., Quang Ngoc Nguyen, Nieto-Martinez, Ramfis E., Niiranen, Teemu J., Nikitin, Yury P., Ninomiya, Toshiharu, Nishtar, Sania, Njelekela, Marina A., Noale, Marianna, Noboa, Oscar A., Noorbala, Ahmad Ali, Norat, Teresa, Nordendahl, Maria, Nordestgaard, Borge G., Noto, Davide, Nowak-Szczepanska, Natalia, Al Nsour, Mohannad, Nunes, Baltazar, O'Neill, Terence W., O'Reilly, Dermot, Ochimana, Caleb, Oda, Eiji, Odili, Augustine N., Oh, Kyungwon, Ohara, Kumiko, Ohtsuka, Ryutaro, Olie, Valerie, Olinto, Maria Teresa A., Oliveira, Isabel O., Omar, Mohd Azahadi, Onat, Altan, Ong, Sok King, Ono, Lariane M., Ordunez, Pedro, Ornelas, Rui, Ortiz, Pedro J., Osmond, Clive, Ostojic, Sergej M., Ostovar, Afshin, Otero, Johanna A., Overvad, Kim, Owusu-Dabo, Ellis, Paccaud, Fred Michel, Padez, Cristina, Pahomova, Elena, de Paiva, Karina Mary, Pajak, Andrzej, Palli, Domenico, Palmieri, Luigi, Pan, Wen-Harn, Panda-Jonas, Songhomitra, Panza, Francesco, Paoli, Mariela, Papandreou, Dimitrios, Park, Soon-Woo, Park, Suyeon, Parnell, Winsome R., Parsaeian, Mahboubeh, Pasquet, Patrick, Patel, Nikhil D., Pavlyshyn, Halyna, Pecin, Ivan, Pednekar, Mangesh S., Pedro, Joao M., Peer, Nasheeta, Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C., Peres, Karen G. D. A., Peres, Marco A., Peters, Annette, Petkeviciene, Janina, Peykari, Niloofar, Son Thai Pham, Pichardo, Rafael N., Pigeot, Iris, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pitakaka, Freda, Piwonska, Aleksandra, Pizarro, Andreia N., Plans-Rubio, Pedro, Polasek, Ozren, Porta, Miquel, Poudyal, Anil, Pourfarzi, Farhad, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Price, Alison J., Price, Jacqueline F., Providencia, Rui, Puhakka, Soile E., Puiu, Maria, Punab, Margus, Qasrawi, Radwan F., Qorbani, Mostafa, Queiroz, Daniel, Tran Quoc Bao, Radic, Ivana, Radisauskas, Ricardas, Rahimikazerooni, Salar, Rahman, Mahfuzar, Raitakari, Olli, Raj, Manu, Rakhimova, Ellina M., Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramos, Elisabete, Rampal, Lekhraj, Rampal, Sanjay, Rangel Reina, Daniel A., Rarra, Vayia, Rech, Cassiano Ricardo, Redon, Josep, Reganit, Paul Ferdinand M., Regecova, Valeria, Revilla, Luis, Rezaianzadeh, Abbas, Ribeiro, Robespierre, Riboli, Elio, Richter, Adrian, Rigo, Fernando, de Wit, Tobias F. Rinke, Ritti-Dias, Raphael M., Robitaille, Cynthia, Rodriguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, Maria, Rodriguez-Villamizar, Laura A., Roggenbuck, Ulla, Rojas-Martinez, Rosalba, Romaguera, Dora, Romeo, Elisabetta L., Rosengren, Annika, Roy, Joel G. R., Rubinstein, Adolfo, Ruidavets, Jean-Bernard, Sandra Ruiz-Betancourt, Blanca, Ruiz-Castell, Maria, Rusakova, Iuliia A., Russo, Paola, Rutkowski, Marcin, Sabanayagam, Charumathi, Sabbaghi, Hamideh, Sachdev, Harshpal S., Sadjadi, Alireza, Safarpour, Ali Reza, Safi, Sare, Safiri, Saeid, Saidi, Olfa, Saki, Nader, Salanave, Benoit, Salazar Martinez, Eduardo, Salmeron, Diego, Salomaa, Veikko, Salonen, Jukka T., Salvetti, Massimo, Sanchez-Abanto, Jose, Sans, Susana, Santos, Diana A., Santos, Ina S., Santos, Lelita C., Santos, Maria Paula, Santos, Rute, Saramies, Jouko L., Sardinha, Luis B., Sarganas, Giselle, Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savvas, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D., Schargrodsky, Herman, Schipf, Sabine, Schmidt, Carsten O., Schnohr, Peter, Schoettker, Ben, Schramm, Sara, Schultsz, Constance, Schutte, Aletta E., Sebert, Sylvain, Sein, Aye Aye, Sen, Abhijit, Senbanjo, Idowu O., Sepanlou, Sadaf G., Servais, Jennifer, Shalnova, Svetlana A., Shamah-Levy, Teresa, Shamshirgaran, Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K., Shaw, Jonathan E., Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shin, Dong Wook, Shirani, Majid, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M., de Moura Silva, Caroline Ramos, Santos Silva, Diego Augusto, Simon, Mary, Simons, Judith, Simons, Leon A., Sjostrom, Michael, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobngwi, Eugene, Soderberg, Stefan, Soemantri, Agustinus, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Sorensen, Thorkild I. A., Sorgjerd, Elin P., Soric, Maroje, Jerome, Charles Sossa, Soumare, Aicha, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Staessen, Jan A., Starc, Gregor, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D., Stergiou, George S., Stessman, Jochanan, Stieber, Jutta, Stoeckl, Doris, Stocks, Tanja, Stokwiszewski, Jakub, Stronks, Karien, Strufaldi, Maria Wany, Suka, Machi, Sun, Chien-An, Sung, Yn-Tz, Suriyawongpaisal, Paibul, Sy, Rody G., Syddall, Holly E., Sylva, Rene Charles, Szklo, Moyses, Tai, E. Shyong, Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarqui-Mamani, Carolina B., Taylor, Anne, Taylor, Julie, Tebar, William R., Tell, Grethe S., Tello, Tania, Tham, Yih Chung, Thankappan, K. R., Theobald, Holger, Theodoridis, Xenophon, Thinggaard, Mikael, Thomas, Nihal, Thorand, Barbara, Thuesen, Betina H., Timmermans, Erik J., Tjandrarini, Dwi H., Tjonneland, Anne, Toft, Ulla, Tolonen, Hanna K., Tolstrup, Janne S., Topbas, Murat, Topor-Madry, Roman, Jose Tormo, Maria, Tornaritis, Michael J., Torrent, Maties, Torres-Collado, Laura, Touloumi, Giota, Traissac, Pierre, Triantafyllou, Areti, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh T. H., Trivedi, Atul, Tshepo, Lechaba, Tsugane, Shoichiro, Tuliakova, Azaliia M., Tulloch-Reid, Marshall K., Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L., Twig, Gilad, Tynelius, Per, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ulmer, Hanno, Uusitalo, Hannu M. T., Valdivia, Gonzalo, Valvi, Damaskini, van Dam, Rob M., van den Born, Bert-Jan, Van der Heyden, Johan, van der Schouw, Yvonne T., Van Herck, Koen, Hoang Van Minh, Van Schoor, Natasja M., van Valkengoed, Irene G. M., van Zutphen, Elisabeth M., Vanuzzo, Diego, Varbo, Anette, Vasan, Senthil K., Vega, Tomas, Veidebaum, Toomas, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Verschuren, W. M. Monique, Verstraeten, Roosmarijn, Victora, Cesar G., Viet, Lucie, Villalpando, Salvador, Vineis, Paolo, Vioque, Jesus, Virtanen, Jyrki K., Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vlasoff, Tiina, Vollenweider, Peter, Voutilainen, Ari, Wade, Alisha N., Walton, Janette, Wambiya, Elvis O. A., Bebakar, Wan Mohamad Wan, Mohamud, Wan Nazaimoon Wan, Wanderley Junior, Rildo de Souza, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S. Goya, Wareham, Nicholas, Wei, Wenbin, Weres, Aneta, Werner, Bo, Whincup, Peter H., Widhalm, Kurt, Wiecek, Andrzej, Wilks, Rainford J., Willeit, Johann, Willeit, Peter, Williams, Emmanuel A., Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A., Wong, Andrew, Wong, Tien Yin, Woo, Jean, Wu, Frederick C., Wu, Shouling, Wyszynska, Justyna, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yasuharu, Tabara, Ye, Xingwang, Yiallouros, Panayiotis K., Yoosefi, Moein, Yoshihara, Akihiro, You, San-Lin, Younger-Coleman, Novie O., Yusoff, Ahmad Faudzi, Zainuddin, Ahmad A., Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antonis, Elisa Zapata, Maria, Zaw, Ko Ko, Zejglicova, Kristyna, Vrkic, Tajana Zeljkovic, Zeng, Yi, Zhang, Luxia, Zhao, Dong, Zhao, Ming-Hui, Zhen, Shiqi, Zheng, Yingfeng, Zholdin, Bekbolat, Zhu, Dan, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Zoghlami, Nada, Zuniga Cisneros, Julio., School of Medicine, ACS - Diabetes & metabolism, APH - Global Health, Pulmonology, Medical Informatics, Adult Psychiatry, Global Health, APH - Quality of Care, APH - Methodology, Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, Anesthesiology, Graduate School, and ACS - Heart failure & arrhythmias
Subjects: Male, Latin Americans, Nutrition and Disease, Epidemiology, [SDV]Life Sciences [q-bio], Medizin, BLOOD-PRESSURE, 030204 cardiovascular system & hematology, Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants, Hypertension, Prevalence, Control, Tretament, GUIDELINES, Global Health, Worldwide trends, 0302 clinical medicine, Hypertension prevalence, Voeding en Ziekte, Medicine and Health Sciences, kohonnut verenpaine, Medicine, 030212 general & internal medicine, Prevention and Control, 11 Medical and Health Sciences, ComputingMilieux_MISCELLANEOUS, education.field_of_study, food and beverages, Public Health, Global Health, Social Medicine and Epidemiology, General Medicine, Noncommunicable diseases, Period prevalence, Middle Aged, kansainvälinen vertailu, 3142 Public health care science, environmental and occupational health, 3. Good health, MIDDLE-INCOME, Pooled analysis, SYSTEMATIC ANALYSIS, INCOME COUNTRIES, ADULTS, PREVENTION, MANAGEMENT, ADHERENCE, DIAGNOSIS, Western europe, [SDE]Environmental Sciences, Hypertension/diagnosis, NCD Risk Factor Collaboration (NCD-RisC), Female, B990 Subjects Allied to Medicine not elsewhere classified, Life Sciences & Biomedicine, Adult, health-care, esiintyvyys, Central asia, Population, Nursing, 3121 Internal medicine, 03 medical and health sciences, Medicine, General & Internal, Drug Therapy, General & Internal Medicine, Life Science, Humans, ddc:610, education, Antihypertensive Agents, VLAG, Aged, Science & Technology, Antihypertensive Agents/therapeutic use, business.industry, Omvårdnad, fungi, General and internal medicine, Estados de Saúde e de Doença, Taking medication, Treatment, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Blood pressure, Faculdade de Ciências Sociais, 3121 General medicine, internal medicine and other clinical medicine, lääkehoito, 1182 Biochemistry, cell and molecular biology, business, Demography
Abstract: Background: hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. Methods: we used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age. Findings: the number of people aged 30-79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306-359) million women and 317 (292-344) million men in 1990 to 626 (584-668) million women and 652 (604-698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55-62) of women and 49% (46-52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43-51) of women and 38% (35-41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20-27) for women and 18% (16-21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran. Interpretation Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings., British Heart Foundation Centre of Research Excellence Grant; World Health Organization (WHO); Abdul Latif Jameel Institute for Disease and Emergency Analytics Fellowship
Published: 2021
Full Text: View/download PDF

30. On the compactness of the set of L2 trajectories of the control system

Author: Anar Huseyin, Nesir Huseyin, and [Huseyin, Nesir] Cumhuriyet Univ, Dept Math & Sci Educ, Sivas, Turkey -- [Huseyin, Anar] Cumhuriyet Univ, Dept Stat, Sivas, Turkey
Subjects: Computer science, Applied Mathematics, lcsh:QA299.6-433, lcsh:Analysis, Topology, Urysohn integral equation, Set (abstract data type), Compact space, Control system, compactness, control system, set of L-2 trajectories, integral constraint, Analysis
Abstract: WOS: 000435477100008, In this paper, the compactness of the set of L-2 trajectories of the control system described by the Urysohn-type integral equation is studied. The control functions are chosen from the closed ball of the space L-2 with radius r and centered at the origin. Existence of an optimal trajectory of the optimal control problem with lower semicontinuous payoff functional is discussed.
Published: 2018
Full Text: View/download PDF

31. Synthesis and in vitro leishmanicidal activity of novel [1,2,3]triazolo[1,5-a]pyridine salts

Author: Rubén Martín-Escolano, Clotilde Marín, Ramón Guitierrez-Sánchez, Belén Abarca, Manuel Sánchez-Moreno, Rafael Ballesteros, Álvaro Martín-Montes, Rafael Ballesteros-Garrido, [Martin-Montes, Alvaro] Univ Granada, Hosp Univ Granada, Inst Invest Biosanitaria Ibs GRANADA, Granada, Spain, [Martin-Escolano, Ruben] Univ Granada, Hosp Univ Granada, Inst Invest Biosanitaria Ibs GRANADA, Granada, Spain, [Marin, Clotilde] Univ Granada, Hosp Univ Granada, Inst Invest Biosanitaria Ibs GRANADA, Granada, Spain, [Sanchez-Moreno, Manuel] Univ Granada, Hosp Univ Granada, Inst Invest Biosanitaria Ibs GRANADA, Granada, Spain, [Ballesteros-Garrido, Rafael] Univ Valencia, Fac Farm, Dept Quim Organ, Avda Vicente Andres Estelles S-N, E-46100 Valencia, Spain, [Abarca, Beier] Univ Valencia, Fac Farm, Dept Quim Organ, Avda Vicente Andres Estelles S-N, E-46100 Valencia, Spain, [Ballesteros, Rafael] Univ Valencia, Fac Farm, Dept Quim Organ, Avda Vicente Andres Estelles S-N, E-46100 Valencia, Spain, [Ballesteros-Garrido, Rafael] Univ Valencia, ICMol Inst Ciencia Mol, C Catedrat Jose Beltran 2, E-46100 Valencia, Spain, [Guitierrez-Sanchez, Ramon] Univ Granada, Dept Stat, Severo Ochoa S-N, E-18071 Granada, Spain, Ministerio de Ciencia e Innovacion (Spain), Generalitat Valenciana, and Universidad de Valencia (Valencia, Spain)
Subjects: 0301 basic medicine, Inhibitor, General Chemical Engineering, Leishmania donovani, Drug action, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, parasitic diseases, Triazolopyridines, Amastigote, Cytotoxicity, Imidazole, biology, Chronic phases, 010405 organic chemistry, Chemistry, Binding, Vivo trypanosomicidal activity, General Chemistry, biology.organism_classification, Leishmania braziliensis, In vitro, 0104 chemical sciences, 030104 developmental biology, Biochemistry, 1,2,3-triazoles, Antibacterial activity, Pyridinium, Leishmania infantum, Derivatives
Abstract: Leishmaniasis remains a significant worldwide problem; it is of great interest to develop new drugs to fight this disease. Recently we described some [1,2,3] triazolo[1,5-a] pyridine compounds with significant leishmanicidal activity. The importance of water solubility in drug action made us realise that we could transform non charged triazolopyridines into charged analogues that could increase the degree of water solubility. With this objective we report here the synthesis of novel [1,2,3] triazolo[1,5-a] pyridinium salts 2-7 from triazolopyridines 1, and the study of their in vitro leishmanicidal activity. The activity was tested on Leishmania infantum, Leishmania braziliensis and Leishmania donovani parasites, using promastigote and intracellular amastigote forms. The cytotoxicity of the tested compounds on J774.2 macrophage cells was also measured. Five of the tested compounds (2b, 4a, 4c, 6, 7d) showed selectivity indexes higher than those of the reference drug Glucantime for the three Leishmania species. Moreover, the data on infection rate and on amastigotes showed that these compounds are the most active against the three Leishmania species. The changes in the excretion product profiles of parasites treated with the compounds were also consistent with substantial cytoplasmic alterations. On the other hand, the most active compounds were potent inhibitors of Fe-SOD in the three parasite species considered whereas their impact on human CuZn-SOD was low.
Published: 2017
Full Text: View/download PDF

32. PSEUDO PROJECTIVE CURVATURE TENSOR SATISFYING SOME PROPERTIES ON A NORMAL PARACONTACT METRIC MANIFOLD

Author: Ümit Yildirim, Süleyman Dirik, Mehmet Atçeken, Gaziosmanpaşa Üniversitesi, 0-Belirlenecek, and [Yildirim, Umit -- Atceken, Mehmet] Gaziosmanpasa Univ, Fac Arts & Sci, Dept Math, Tokat, Turkey -- [Dirik, Suleyman] Amasya Univ, Fac Arts & Sci, Dept Stat, Amasya, Turkey
Subjects: Physics, concircular curvature tensor, Pure mathematics, Riemann curvature tensor, [Anahtar Kelime Yok], 010102 general mathematics, General Medicine, Curvature, Ricci tensor, 01 natural sciences, Manifold, Paracontact metric manifold,Ricci tensor,concircular curvature tensor, 010101 applied mathematics, symbols.namesake, paracontact metric manifold, Metric (mathematics), symbols, Mathematics::Differential Geometry, 0101 mathematics, Projective test, Computer Science::Data Structures and Algorithms, Ricci curvature, Flatness (mathematics)
Abstract: WOS: 000463698900083 In the present paper we have studied the curvature tensor of a normal paracontact metric manifold satisfying the conditions R(xi, X)(p) over tilde = 0, (P) over tilde(xi,X)(P) over tilde = 0, (P) over tilde(xi,X)S = 0, (P) over tilde(xi,X)(Z) over tilde = 0 and pseudo projective flatness, where R, (P) over tilde, S and (Z) over tilde denote the Riemannian curvature, pseudo projective curvature, Ricci and concircular curvature tensors, respectively.
Published: 2019

33. Determination Of Se, Cr, Mn, Zn, Co, Na, And K In Blood Samples Of Breast Cancer Patients To Investigate Their Variation Using Icp-Ms And Icp-Oes

Author: Önder Eyecioğlu, Orhan İçelli, Omer Topdagi, Sezgin Bakırdere, Mustafa Çağlar, Ozan Toker, Ertuğrul Osman Bursalıoğlu, Yaşar Karabul, Ersoy Öz, Toker, Ozan, Karabul, Yasar, Icelli, Orhan Yildiz Tech Univ, Dept Phys, Istanbul, Turkey, Topdagi, Omer Ataturk Univ, Dept Med, Erzurum, Turkey, Bakirdere, Sezgin Yildiz Tech Univ, Dept Chem, Istanbul, Turkey, Bursalioglu, Ertugrul Osman Sinop Univ, Dept Bioengn, Sinop, Turkey, Oz, Ersoy Yildiz Tech Univ, Dept Stat, Istanbul, Turkey, Eyecloglu, Onder Nisantasi Univ, Dept Comp Engn, Istanbul, Turkey, and Caglar, Mustafa Istanbul Medipol Univ, Dept Med Phys, Istanbul, Turkey
Subjects: Investigate, Breast cancer, Chemistry, Inductively coupled plasma atomic emission spectroscopy, Breast Cancer, medicine, medicine.disease, Determination, Inductively coupled plasma mass spectrometry, Spectroscopy, Nuclear chemistry
Abstract: WOS: 000466279600002 The aim of this study was to investigate the concentration changes of Se, Mn, Cr, Zn, Co, Na and K in blood samples of breast cancer patients. Determination of the elements was performed using ICP-MS and ICP-OES instruments. Kolmogorov-Smirnov normality tests, Mann-Whitney U tests, Independent sample T tests and Spearman's rank correlation tests were performed for statistical comparisons. It was found that the concentrations of Na and K in breast cancer patients were higher than for healthy people. The Se, Mn, and Cr concentrations were found to be lower in patients with breat cancer. No increase/decrease in Zn concentrations between the two groups was observed. A positive correlation was found between the distribution of Zn and K elements. Independent sample t and Mann-Whitney U tests demonstrated that statistical differences were observed between patients having the diagnosis of breast cancer and healthy people in terms of the concentrations of Se, Cr and Na. The results presented in this study will contribute to the literature by showing the relationship between breast cancer and element concentrations. TUBITAK [2210C]; Yildiz Technical University BAP [2015-01-01-YL04, 832] This research was supported financially by TUBITAK (2210C) and Yildiz Technical University BAP (2015-01-01-YL04, 832)
Published: 2019

34. Is There Any Relation Between Type 1 Halitosis and Oral Candida Colonisation?

Author: Aydin, Murat, Derici, Mustafa Cagri, Unal, Yener, Yeler, Defne, Demir, Yusuf Islam, [Derici, Mustafa Cagri] Adana Numune Educ & Res Hosp, Clin Ear Nose & Throat, Adana, Turkey -- [Unal, Yener] Cumhuriyet Univ, Dept Stat & Comp Sci, Fac Sci, Sivas, Turkey -- [Yeler, Defne] Cumhuriyet Univ, Dept Oral & Maxillofacial Radiol, Fac Dent, Sivas, Turkey -- [Demir, Yusuf Islam] Ataturk Univ, Fac Dent, Erzurum, Turkey, and Aydin, Murat -- 0000-0003-0030-8999
Subjects: halitosis, hydrogen sulfide, breath tests, Candida
Abstract: WOS: 000465377600007, PubMed ID: 31130123, Pathologic halitosis has been classified into 5 types: oral, airway, gastroesophageal, blood-borne and subjective, respectively. Type 1 (oral) halitosis mostly takes origin from anaerobic bacterial activities on oral surfaces. The role of anaerobic bacterial activities is clearly demonstrated, but despite the large number of anectodal claims, the role of Candida in patients with halitosis has not been adequately investigated. The aim of this study was to confirm the relationship between Candida and halitosis. A total of 136 subjects were enrolled and divided into two groups. The study group comprised of 69 patients with halitosis who had over 0.7 ppm H2S concentration in their oral cavity and the control group comprised of 67 healthly subjects. Self assesment scores for halitosis, Candida colony counts in saliva samples, oral NH3, SO2, H2S, H-2 and volatile organic gas concentrations were recorded. H2S producing capacity of subjects was quantified by applying cysteine challenge test. Candida samples were taken from the mouths of the patients with and without halitosis, and Candida albicans isolates were inoculated into broth medium. After 3 days of incubation at 37 degrees C, gas concentrations of the headspace of the flasks were read by a portable multigas detector. The rate of Candida positivity was 44.9% in the study group while it was 46.3% in the control group. There was no statistical significant difference between the groups according to the Candida growth (p=0.561). The oral gas concentrations were comparable in both groups (p
Published: 2019

35. Approximation of the integral funnel of the Urysohn type integral operator

Author: Anar Huseyin and [Huseyin, Anar] Cumhuriyet Univ, Fac Sci, Dept Stat, TR-58140 Sivas, Turkey
Subjects: 0209 industrial biotechnology, business.product_category, Discretization, Integral funnel, Applied Mathematics, Mathematical analysis, 020206 networking & telecommunications, 65R10, 02 engineering and technology, Computational Mathematics, 020901 industrial engineering & automation, Hausdorff distance, MSC 45P05, 0202 electrical engineering, electronic engineering, information engineering, Urysohn integral operator, Funnel, Ball (mathematics), business, Finite set, Approximation, Mathematics
Abstract: WOS: 000446451300018, The integral funnel of the closed ball of the space L-p, p > 1, with radius r and centered at the origin under Urysohn type integral operator is defined as the set of graphs of the images of all functions from given ball. Approximation of the integral funnel is considered. The closed ball of the space L-p, p > 1, with radius r is replaced by the set consisting of a finite number of functions. The Hausdorffdistance between integral funnel and the set consisting of the sections of the graphs of images of a finite number of functions is evaluated. It is proved that in the case of appropriate choosing of the discretization parameters the approximating sets converges to the integral funnel. (c) 2018 Elsevier Inc. All rights reserved.
Published: 2019

36. USING EXPLORATORY FACTOR ANALYSIS TO IMPROVE THE CALIBRATION OF SLEUTH URBAN GROWTH MODELS

Author: Ayazli, Ismail Ercument, Bilen, Omer, and [Ayazli, Ismail Ercument] Cumhuriyet Univ, Dept Geomat Engn, Univ Campus, TR-58140 Sivas, Turkey -- [Bilen, Omer] Yildiz Tech Univ, Dept Stat, Davutpasa Campus, TR-34220 Istanbul, Turkey
Subjects: Urban Growth Simulation Models, Exploratory Factor Analysis, Cellular Automata Model Calibration, SLEUTH
Abstract: 19th International MESAEP Symposium on Environmental Pollution and its Impact on Life in the Mediterranean Region -- OCT 04-06, 2017 -- Natl Res Council Headquarters, Rome, ITALY, WOS: 000461270700051, Simulation models based on cellular automata (CA) are often used to track changes in land cover caused by urban growth. The main program for these models is the SLEUTH Urban Growth Model, which is open source and free. This program uses Monte Carlo (MC) iteration in three phases: testing, calibration, and prediction. Calibration is based on 13 variables. The goal of this study is to test the effectiveness of exploratory factor analysis (EFA), a previously untested method, to improve the calibration of CA-based urban growth models. EFA was evaluated against two commonly-used methods, Lee-Sallee and Optimum SLEUTH Metrics (OSM), using synthetic test data from the Project Gigalopolis website. The results show that EFA had highest regression scores for six of the 13 metrics, performing better than OSM with high scores in four variables and Lee-Sallee with high scores in just three variables. Improving calibration with EFA will result in more accurate models and predictions of urban growth., Mediterranean Sci Assoc Environm Protect, Cumhuriyet University under CUBAP [M 673], The authors would like to thank Cumhuriyet University because of support the study under CUBAP project numbered M 673.
Published: 2019

37. Individual heterogeneity in life‐history trade‐offs with age at first reproduction in capital breeding elephant seals

Author: Marthán N Bester, Res Altwegg, W. Chris Oosthuizen, Roger Pradel, Marie Nevoux, Martin Postma, P J Nico de Bruyn, Department of Zoology and Entomology, University of Pretoria [South Africa], Kirstenbosch Research Centre, South African National Biodiversity Institute, Écologie et santé des écosystèmes (ESE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-École pratique des hautes études (EPHE)-Université de Montpellier (UM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université Paul-Valéry - Montpellier 3 (UM3), University of Cape Town, Dept Stat Sci, Ctr Stat Ecol Environm & Conservat, Rondebosch, Université Paul-Valéry - Montpellier 3 (UPVM)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), University of Pretoria, Mammal Res Inst, Dept Zool & Entomol, Hatfield, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA)-Université Paul-Valéry - Montpellier 3 (UPVM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut de Recherche pour le Développement (IRD [France-Sud])
Subjects: 0106 biological sciences, Offspring, media_common.quotation_subject, Population, Biology, 010603 evolutionary biology, 01 natural sciences, cost of reproduction, individual quality, Seasonal breeder, Life history, mixture models, education, Ecology, Evolution, Behavior and Systematics, ComputingMilieux_MISCELLANEOUS, media_common, hidden heterogeneity, education.field_of_study, Individual heterogeneity, recruitment age, 010604 marine biology & hydrobiology, Trade offs, Capital (economics), Reproduction, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, Demography
Abstract: International audience; ecruitment age plays a key role in life-history evolution. Because individuals allocate limited resources among competing life-history functions, theory predicts trade-offs between current reproduction and future growth, survival and/or reproduction. Reproductive costs tend to vary with recruitment age, but may also be overridden by fixed individual differences leading to persistent demographic heterogeneity and positive covariation among demographic traits at the population level. We tested for evidence of intra- and inter-generational trade-offs and individual heterogeneity relating to age at first reproduction using three decades of detailed individual life-history data of 6,439 capital breeding female southern elephant seals. Contrary to the predictions from trade-off hypotheses, we found that recruitment at an early age was associated with higher population level survival and subsequent breeding probabilities. Nonetheless, a survival cost of first reproduction was evident at the population level, as first-time breeders always had lower survival probabilities than prebreeders and experienced breeders of the same age. However, models accounting for hidden persistent demographic heterogeneity revealed that the trade-off between first reproduction and survival was only expressed in "low quality" individuals, comprising 35% of the population. The short-term somatic costs associated with breeding at an early age had no effect on the ability of females to allocate resources to offspring in the next breeding season. Our results provide strong evidence for individual heterogeneity in the life-history trajectories of female elephant seals. By explicitly modeling hidden persistent demographic heterogeneity we show that individual heterogeneity governs the expression of trade-offs with first reproduction in elephant seals.
Published: 2019
Full Text: View/download PDF

38. Pseudo-slant submanifolds in cosymplectic space forms

Author: Süleyman Dirik, Mehmet Atçeken, and [Dirik, Suleyman] Amasya Univ, Fac Arts & Sci, Dept Stat, Amasya, Turkey -- [Atceken, Mehmet] Gaziosmanpasa Univ, Fac Arts & Sci, Dept Math, Tokat, Turkey
Subjects: Pure mathematics, General Mathematics, Mathematics::History and Overview, 010102 general mathematics, cosymplectic manifold, Space (mathematics), Topology, 53d10, 01 natural sciences, 53c25, Computer Science::Computers and Society, 53d15, 53c15, cosymplectic space form, 53c17, Computer Science::Computer Vision and Pattern Recognition, QA1-939, Mathematics::Differential Geometry, 0101 mathematics, Mathematics::Symplectic Geometry, Mathematics, pseudo-slant submanifold
Abstract: In this paper, we study the geometry of the pseudo-slant submanifolds of a cosymplectic space form. Necessary and sufficient conditions are given for a submanifold to be a pseudo-slant submanifold, pseudo-slant product, mixed geodesic and totally geodesic in cosymplectic manifolds. Finally, we give some results for totally umbilical pseudo-slant submanifold in a cosymplectic manifold and cosymplectic space form.
Published: 2016
Full Text: View/download PDF

39. Approximation of the set of trajectories of the nonlinear control system with limited control resources

Author: Anar Huseyin, Nesir Huseyin, Khalik G. Guseinov, [Huseyin, Nesir] Cumhuriyet Univ, Fac Educ, Dept Math & Sci Educ, TR-58140 Sivas, Turkey -- [Huseyin, Anar] Cumhuriyet Univ, Fac Educ, Dept Stat, TR-58140 Sivas, Turkey -- [Guseinov, Khalik] Anadolu Univ, Fac Sci, Dept Math, TR-26470 Eskisehir, Turkey, Anadolu Üniversitesi, Fen Fakültesi, Matematik Bölümü, and Hüseyin, Haluk
Subjects: 010102 general mathematics, 010103 numerical & computational mathematics, Nonlinear control, Type (model theory), 01 natural sciences, Integral equation, nonlinear integral equation, Constraint (information theory), Set (abstract data type), Hausdorff distance, Modeling and Simulation, Control system, set of trajectories, QA1-939, Applied mathematics, 0101 mathematics, control system, Finite set, approximation, Mathematics, Analysis, integral constraint
Abstract: WOS: 000429148100010, In this paper the control system described by a Urysohn type integral equation is studied. It is assumed that the control functions have integral constraint. Approximation of the set of trajectories generated by all admissible control functions is considered. Step by step way, the set of admissible control functions is replaced by a set consisting of a finite number of control functions which generates a finite number of trajectories. An evaluation of the Hausdorff distance between the set of trajectories of the system and the set, consisting of a finite number of trajectories is obtained.
Published: 2018

40. Triple test with tumor markers CYFRA 21.1, HE4, and ProGRP might contribute to diagnosis and subtyping of lung cancer

Author: Emin Maden, Salih Emri, Elif Tugce Korkmaz, Filiz Akbiyik, Sevgen Onder, Z. Gunnur Dikmen, Deniz Koksal, Duygu İçen, Funda Aksu, Emri, Salih, and [Korkmaz, Elif Tugce] Aksaray Univ, Educ & Res Hosp, Dept Chest Dis, Aksaray, Turkey -- [Koksal, Deniz] Hacettepe Univ, Sch Med, Dept Chest Dis, TR-06100 Ankara, Turkey -- [Aksu, Funda] Ataturk Chest Dis & Chest Surg Educ & Res Hosp, Dept Chest Dis, Ankara, Turkey -- [Dikmen, Z. Gunnur -- Akbiyik, Filiz] Hacettepe Univ, Dept Med Biochem, Ankara, Turkey -- [Icen, Duygu] Hacettepe Univ, Dept Stat, Ankara, Turkey -- [Maden, Emin] Yuzuncu Yil Hosp, Dept Chest Dis, Van, Turkey -- [Onder, Sevgen] Hacettepe Univ, Dept Pathol, Ankara, Turkey -- [Emri, Salih] Altinbas Univ, Sch Med, Dept Chest Dis, Istanbul, Turkey -- [Korkmaz, Elif Tugce -- Aksu, Funda -- Maden, Emin -- Akbiyik, Filiz -- Emri, Salih] Hacettepe Univ, Sch Med, Ankara, Turkey
Subjects: Adult, Male, medicine.medical_specialty, Lung Neoplasms, Clinical Biochemistry, Small-cell carcinoma, Gastroenterology, 03 medical and health sciences, Cytokeratin, 0302 clinical medicine, WAP Four-Disulfide Core Domain Protein 2, Antigens, Neoplasm, Internal medicine, Diagnosis, medicine, Biomarkers, Tumor, Humans, 030212 general & internal medicine, Prospective Studies, CYFRA 21-1, Lung cancer, Tumor Markers, Aged, Keratin-19, medicine.diagnostic_test, biology, business.industry, Triple test, Lung Cancer, Area under the curve, Chromogranin A, Proteins, General Medicine, Middle Aged, medicine.disease, Small Cell Lung Carcinoma, Peptide Fragments, Recombinant Proteins, Neoplasm Proteins, 030220 oncology & carcinogenesis, Tumor markers, biology.protein, Adenocarcinoma, Female, business, Biomarkers
Abstract: WOS: 000438388500003, PubMed: 29729229, Background and aim: Early diagnosis and histological subtyping are important issues in the management of patients with lung cancer (LC). The aim of this study is to investigate the diagnostic value of a panel of serum tumor markers in newly diagnosed patients with LC. Methods: Venous blood samples were collected from 99 patients with LC (42 adenocarcinoma, 35 squamous, and 22 small cell carcinoma) and 30 patients with benign lung disease. Progastrin releasing peptide (ProGRP), squamous cell carcinoma antigen (SCCAg), cytokeratin 19-fragments (CYFRA 21.1), human epididymis protein 4 (HE4), Chromogranin A (CgA) and neuron specific enolase (NSE) levels were measured. The diagnostic value of the biomarkers was assessed with ROC curve analyses; the area under the curve (AUC) was calculated. Results: Serum CYFRA 21.1, ProGRP, SCCAg, NSE levels were significantly higher in LC patients. While ProGRP levels were higher (p = 0.009) in SCLC; CYFRA 21.1 and SCCAg levels were higher in NSCLC (p = 0.019 and p = 0.001, respectively). The sensitivity and specificity of tumor markers were 72%, 83% for CYFRA 21.1; 70%, 57% for HE4; 18%, 93% for ProGRP; 43%, 77% for SCCAg; 54%, 53% for CgA; 73%, 50% for NSE. CYFRA 21.1 (p < 0.001, r = 0.394), HE4 (p = 0.014, r = 0.279) and CgA (p = 0.023, r = 0.259) levels were positively correlated with tumor stage in NSCLC. CgA levels were significantly higher in extensive stage SCLC (p = 0.004). CYFRA 21.1 had the highest diagnostic value for LC (AUC = 0.865). When it is combined with HE4, diagnostic value increased (AUC = 0.899). ProGRP had the highest diagnostic value (AUC = 0.875, p < 0.001) for discriminating SCLC from NSCLC. Conclusion: A panel of three tumor markers CYFRA 21.1, HE4 and ProGRP may play a role for discriminating LC from benign lung disease and subtyping as SCLC., Hacettepe University Scientific Research Unit [014D12101003-818], Study was supported by Hacettepe University Scientific Research Unit (Project ID: 014D12101003-818).
Published: 2018

41. Test anxiety and self-esteem in senior high school students: a cross-sectional study

Author: Gunal Bilek, Ekrem Çelik, Seda Aybuke Sari, [Sari, Seda Aybuke] Cumhuriyet Univ, Dept Child & Adolescent Psychiat, Sivas, Turkey -- [Bilek, Gunal] Bitlis Eren Univ, Dept Stat, Bitlis, Turkey -- [Celik, Ekrem] Bitlis Sci High Sch, Bitlis, Turkey, and Bilek, Gunal -- 0000-0001-6417-7129
Subjects: Male, Adolescent, Turkey, Universities, Cross-sectional study, Performance Anxiety, media_common.quotation_subject, education, 050109 social psychology, Young Adult, Surveys and Questionnaires, medicine, Humans, 0501 psychology and cognitive sciences, Students, Test anxiety, media_common, self-esteem, Internet, Schools, students, 05 social sciences, Self-esteem, 050301 education, medicine.disease, Self Concept, Psychiatry and Mental health, Cross-Sectional Studies, Female, Psychology, 0503 education, Clinical psychology
Abstract: WOS: 000419981300002, PubMed ID: 29037120, Purpose: In this study, it is aimed to determine the level of test anxiety and self-esteem in the high school students preparing for the university exam in Bitlis, Turkey, and to investigate the effect of test anxiety on self-esteem.Material and methods: Seven-hundred and twenty-four high school students who were preparing for the university entrance examination in Bitlis participated in the study. A questionnaire which includes socio-demographic data form, Rosenberg Self-Esteem Scale and Revised Test Anxiety Scale was prepared as an e-questionnaire for the students to fill easily and uploaded to the Bitlis State Hospital's website. Schools were called and informed for the students to fill out the e-questionnaire on the Internet.Results: The most important findings from our study are that gender is influential on test anxiety and self-esteem score and test anxiety level are negatively correlated. It was observed that female students had more test anxiety than male students and those who had higher self-esteem had less test anxiety.Conclusion: Consequently, our study shows that university entrance examination creates anxiety on students and reduces self-esteem, especially in female students.
Published: 2018

42. Effects of MPO-463G/A and -129G/A polymorphisms on coronary artery disease risk and patient survival in a Turkish population

Author: Arslan, Serdal, Berkan, Ocal, Bayyurt, Burcu, Beton, Osman, Sahin, Nil Ozbilum, Aydemir, Eylem Itir, and [Arslan, Serdal -- Bayyurt, Burcu] Cumhuriyet Univ, Fac Med, Dept Med Biol, Kayseri St, TR-58140 Sivas, Turkey -- [Berkan, Ocal] Cumhuriyet Univ, Ctr Heart, Dept Cardiovasc Surg, Sivas, Turkey -- [Beton, Osman] Cumhuriyet Univ, Ctr Heart, Dept Cardiol, Sivas, Turkey -- [Sahin, Nil Ozbilum] Cumhuriyet Univ, Fac Sci, Dept Mol Biol & Genet, TR-58140 Sivas, Turkey -- [Aydemir, Eylem Itir] Cumhuriyet Univ, Fac Sci, Dept Stat, TR-58140 Sivas, Turkey
Subjects: myeloperoxidase, genetic polymorphism, Articles, coronary artery disease
Abstract: WOS: 000417417400010, Myeloperoxidase (MPO) is an oxidative hemoprotein compound expressed in polymorphonuclear leukocytes that contributes to inflammatory responses. Coronary artery disease (CAD), as the most prevalent form of heart disease, is considered to originate from an interaction between genetic and environmental factors. In the present study, the potential associations between MPO-463G/A and -129G/A polymorphisms with CAD were investigated in a Turkish population using a polymerase chain reaction-based restriction fragment length polymorphism (RFLP) assay technique. To the best of our knowledge, the study was the first to examine the association of MPO-463G/A and -129G/A with patient survival rate in a Turkish population. The study population consisted of 201 patients with CAD and 201 healthy controls. The results indicated that there was a significant association of the GA genotype of MPO-463G/A with the case population (P=0.048). Meanwhile, in the patients with CAD, the frequency distributions of the MPO-129A allele (P=0.006) and GA genotype (P=0.001) were significantly increased compared with the G allele and GG genotype, respectively, in CAD patients. Additionally, compared with the GG genotype, the frequency distribution of MPO-129A was significantly increased in the patient group regarding smoking status (P=0.001) and the presence of hypercholester-olemia (P=0.028). However, survival analysis did not detect an effect of either polymorphism on the survival rate of the CAD patients (P>0.05). Therefore, the MPO-129GA genotype may be a significant risk factor for the development of CAD., Research Council of Cumhuriyet University, Sivas, Turkey [F-340], The present study was supported by the Research Council of Cumhuriyet University, Sivas, Turkey (grant no. F-340).
Published: 2017

43. Approximate Bayesian Computation using Random Forest

Author: Marin, Jean-Michel, Pudlo, Pierre, Raynal, Louis, Estoup, Arnaud, Robert, Christian P., Institut Montpelliérain Alexander Grothendieck (IMAG), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie Computationnelle (IBC), Université de Montpellier (UM)-Institut National de la Recherche Agronomique (INRA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS), Institut de Mathématiques de Marseille (I2M), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Univ Warwick, Dept Stat, Coventry, W Midlands, England, Partenaires INRAE, PSL Res Univ, Univ Paris Dauphine, Paris, France, Banff International Research Station for Mathematical Innovation and Discovery (BIRS). MEX., Institut National de la Recherche Agronomique (INRA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), and University of Warwick [Coventry]
Subjects: [STAT.AP]Statistics [stat]/Applications [stat.AP], ComputingMilieux_MISCELLANEOUS
Abstract: International audience
Published: 2017

44. Clinical features and short-term outcomes of cancer patients with suspected and unsuspected pulmonary embolism: the EPIPHANY study

Author: Font, Carme, Carmona-Bayonas, Alberto, Beato, Carmen, Reig, Oscar, Saez, Antonia, Jimenez-Fonseca, Paula, Plasencia, Juana M., Calvo-Temprano, David, Sanchez, Marcelo, Benegas, Mariana, Biosca, Mercedes, Varona, Diego, Angeles Vicente, Maria, Faez, Laura, del Pilar Solis, Maria, de la Haba, Irma, Antonio, Maite, Madridano, Olga, Castanon, Eduardo, Jose Martinez, Maria, Marchena, Pablo, Ramchandani, Avinash, Dominguez, Angel, Puerta, Alejandro, Martinez de la Haza, David, Pueyo, Jesus, Hernandez, Susana, Fernandez-Plaza, Angela, Martinez-Encarnacion, Lourdes, Martin, Mar, Marin, Gema, Ayala, Francisco, Vicente, Vicente, Otero, Remedios, Asociacion Invest Enfermedad Tromo, [Font, Carme] Hosp Clin Barcelona, Dept Med Oncol, IDIBAPS Translat Genom & Targeted Therapeut Solid, Villarroel 170, E-08036 Barcelona, Spain, [Reig, Oscar] Hosp Clin Barcelona, Dept Med Oncol, IDIBAPS Translat Genom & Targeted Therapeut Solid, Villarroel 170, E-08036 Barcelona, Spain, [Carmona-Bayonas, Alberto] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain, [Angeles Vicente, Maria] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain, [Ayala, Francisco] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain, [Vicente, Vicente] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain, [Beato, Carmen] Hosp Nisa Aljarafe, Dept Med Oncol, Seville, Spain, [Saez, Antonia] Axioma Comunicac, Dept Stat, Seville, Spain, [Jimenez-Fonseca, Paula] Hosp Univ Cent Asturias, Dept Med Oncol, Oviedo, Spain, [Faez, Laura] Hosp Univ Cent Asturias, Dept Med Oncol, Oviedo, Spain, [del Pilar Solis, Maria] Hosp Univ Cent Asturias, Dept Med Oncol, Oviedo, Spain, [Plasencia, Juana M.] Hosp Univ Morales Meseguer, Dept Radiol, Murcia, Spain, [Calvo-Temprano, David] Hosp Univ Cent Asturias, Dept Radiol, Oviedo, Spain, [Sanchez, Marcelo] Hosp Clin Barcelona, Radiodiagnost Dept, Barcelona, Spain, [Benegas, Mariana] Hosp Clin Barcelona, Radiodiagnost Dept, Barcelona, Spain, [Biosca, Mercedes] Hosp Univ Vall Hebron, Dept Med Oncol, Barcelona, Spain, [Varona, Diego] Hosp Univ Vall Hebron, Dept Radiol, Barcelona, Spain, [de la Haba, Irma] Hosp Llobregat, Hosp Duran & Reynals, Inst Catalad Oncol, Dept Med Oncol, Barcelona, Spain, [Antonio, Maite] Hosp Llobregat, Hosp Duran & Reynals, Inst Catalad Oncol, Dept Med Oncol, Barcelona, Spain, [Madridano, Olga] Hosp Infanta Sof San Sebastian Ios Reves, Dept Internal Med, Madrid, Spain, [Martin, Mar] Hosp Infanta Sof San Sebastian Ios Reves, Dept Internal Med, Madrid, Spain, [Castanon, Eduardo] Univ Navarra Clin, Dept Med Oncol, Pamplona, Spain, [Jose Martinez, Maria] Hosp Santa Lucia, Dept Med Oncol, Murcia, Spain, [Marchena, Pablo] Hosp San Juan Dios, Dept Internal Med, Esplugues Llobregat, Barcelona, Spain, [Ramchandani, Avinash] Hosp Insular Gran Canaria, Dept Med Oncol, Las Palmas Gran Canaria, Spain, [Dominguez, Angel] Hosp Nisa Aljarafe, Dept Radiol, Seville, Spain, [Puerta, Alejandro] Hosp Reina Sofia, Dept Radiol, Murcia, Spain, [Martinez de la Haza, David] Hosp Llobregat, Hosp Duran & Reynals, Inst Catalad Oncol, Dept Radiol, Barcelona, Spain, [Pueyo, Jesus] Univ Navarra Clin, Dept Radiol, Pamplona, Spain, [Hernandez, Susana] Hosp Infanta Sofia San Sebastian los Reves, Dept Radiol, Madrid, Spain, [Fernandez-Plaza, Angela] Hosp Santa Lucia, Dept Radiol, Murcia, Spain, [Martinez-Encarnacion, Lourdes] Hosp Santa Lucia, Dept Radiol, Murcia, Spain, [Marin, Gema] Hosp Clin Univ Virgen la Arrixaca, Dept Med Oncol, Murcia, Spain, [Otero, Remedios] HUVR IBiS, CIBERES, Dept Pneumol, Seville, Spain, and LEO Pharma Spain
Subjects: Male, Time Factors, 030204 cardiovascular system & hematology, Cohort Studies, 0302 clinical medicine, Risk Factors, Neoplasms, Diagnosis, Young adult, Aged, 80 and over, Adversely impact survival, Mortality rate, Venous Thromboembolism, Middle Aged, Pulmonary embolism, 030220 oncology & carcinogenesis, Cohort, Female, medicine.symptom, Cohort study, Venous thromboembolism, Pulmonary and Respiratory Medicine, Adult, Risk, medicine.medical_specialty, Adolescent, Hemorrhage, Guidelines, Asymptomatic, Risk Assessment, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Humans, Aged, Performance status, business.industry, Outpatient management, Severity index, Cancer, medicine.disease, Surgery, Logistic Models, Spain, Multivariate Analysis, business, Pulmonary Embolism, Tomography, X-Ray Computed, Prognostic model
Abstract: The study aimed to identify predictors of overall 30-day mortality in cancer patients with pulmonary embolism including suspected pulmonary embolism (SPE) and unsuspected pulmonary embolism (UPE) events. Secondary outcomes included 30- and 90-day major bleeding and venous thromboembolism (VTE) recurrence.The study cohort included 1033 consecutive patients with pulmonary embolism from the multicentre observational ambispective EPIPHANY study (March 2006–October 2014). A subgroup of 497 patients prospectively assessed for the study were subclassified into three work-up scenarios (SPE, truly asymptomatic UPE and UPE with symptoms) to assess outcomes.The overall 30-day mortality rate was 14%. The following variables were associated with the overall 30-day mortality on multivariate analysis: VTE history, upper gastrointestinal cancers, metastatic disease, cancer progression, performance status, arterial hypotension 110 beats·min−1, basal oxygen saturation versus overall UPE).The overall 30-day mortality was significantly lower in patients with truly asymptomatic UPE events (3%) compared with those with UPE-S (20%) and SPE (21%) (pIn conclusion, variables associated with the severity of cancer and pulmonary embolism were associated with short-term mortality. Our findings may help to develop pulmonary embolism risk-assessment models in this setting.
Published: 2017

45. Library of Seleno-Compounds as Novel Agents against Leishmania Species

Author: Manuel Sánchez-Moreno, Marta Díaz, Clotilde Marín, Carmen Sanmartín, Rubén Martín-Escolano, Esther Moreno, Daniel Plano, Silvia Pérez-Silanes, Socorro Espuelas, Verónica Alcolea, Ramón Gutiérrez-Sánchez, Álvaro Martín-Montes, [Martin-Montes, Alvaro] Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, [Martin-Escolano, Ruben] Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, [Marin, Clotilde] Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, [Sanchez-Moreno, Manuel] Univ Granada, Fac Ciencias, Dept Parasitol, Severo Ochoa S-N, Granada, Spain, [Martin-Montes, Alvaro] Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Martin-Escolano, Ruben] Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Marin, Clotilde] Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Sanchez-Moreno, Manuel] Hosp Univ Granada, Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Plano, Daniel] Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, [Alcolea, Veronica] Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, [Diaz, Marta] Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, [Perez-Silanes, Silvia] Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, [Sanmartin, Carmen] Univ Navarra, Fac Pharm & Nutr, Dept Organ & Pharmaceut Chem, Campus Univ, Pamplona, Spain, [Plano, Daniel] Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, [Alcolea, Veronica] Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, [Diaz, Marta] Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, [Sanmartin, Carmen] Inst Invest Sanitaria Navarra, IdiSNA, Pamplona, Spain, [Perez-Silanes, Silvia] Univ Navarra, Inst Trop Hlth, Pamplona, Spain, [Espuelas, Socorro] Univ Navarra, Inst Trop Hlth, Pamplona, Spain, [Moreno, Esther] Univ Navarra, Inst Trop Hlth, Pamplona, Spain, [Gutierrez-Sanchez, Ramon] Univ Granada, Dept Stat, Severo Ochoa S-N, Granada, Spain, Spanish MINECO, FEDER, FIMA (Fundacion para la Investigacion Medica Aplicada) project, and FPU grant from Ministry of Education of Spain
Subjects: 0301 basic medicine, glucose metabolism, 030106 microbiology, Antiprotozoal Agents, Leishmania braziliensis, Superoxide dismutase, In-vitro, 03 medical and health sciences, Selenium, Meglumine, Parasitic Sensitivity Tests, Redox modulators, Organometallic Compounds, Parasite hosting, Animals, Humans, Organoselenocyanates, Pharmacology (medical), Leishmania infantum, Trypanosomatids, Cytotoxicity, Amastigote, Drug-resistance, Visceral leishmaniasis, Pharmacology, Leishmania, Meglumine Antimoniate, biology, Chemistry, Superoxide Dismutase, Promastigotes, Biosynthesis, Potent antileishmanial agents, biology.organism_classification, In vitro, Metabolism, 030104 developmental biology, Infectious Diseases, Biochemistry, biology.protein, Diselenides
Abstract: The in vitro leishmanicidal activities of a series of 48 recently synthesized selenium derivatives against Leishmania infantum and Leishmania braziliensis parasites were tested using promastigotes and intracellular amastigote forms. The cytotoxicity of the tested compounds for J774.2 macrophage cells was also measured in order to establish their selectivity. Six of the tested compounds (compounds 8, 10, 11, 15, 45, and 48) showed selectivity indexes higher than those of the reference drug, meglumine antimonate (Glucantime), for both Leishmania species; in the case of L. braziliensis , compound 20 was also remarkably selective. Moreover, data on infection rates and amastigote numbers per macrophage showed that compounds 8, 10, 11, 15, 45, and 48 were the most active against both Leishmania species studied. The observed changes in the excretion product profile of parasites treated with these six compounds were also consistent with substantial cytoplasmic alterations. On the other hand, the most active compounds were potent inhibitors of Fe superoxide dismutase (Fe-SOD) in the two parasite species considered, whereas their impact on human CuZn-SOD was low. The high activity, low toxicity, stability, low cost of the starting materials, and straightforward synthesis make these compounds appropriate molecules for the development of affordable antileishmanicidal agents.
Published: 2017

46. Towards personalized therapy for multiple sclerosis: prediction of individual treatment response

Author: Suzanne Hodgkinson, Patrizia Sola, Jose Luis Sanchez-Menoyo, Mark Slee, Vahid Shaygannejad, Alexandre Prat, Jeannette Lechner-Scott, Lukas Sobisek, Raymond Hupperts, Vincent Van Pesch, Cristina Ramo-Tello, Csilla Rozsa, Guillermo Izquierdo, Helmut Butzkueven, Fraser Moore, Pamela A. McCombe, Maria Laura Saladino, Murat Terzi, Vilija Jokubaitis, Cavit Boz, Eugenio Pucci, Raed Alroughani, Shlomo Flechter, Pierre Grammond, Roberto Bergamaschi, G. Iuliano, Daniele Spitaleri, Francois Grand'Maison, Ali Manouchehrinia, Pierre Duquette, Tomas Kalincik, Marc Girard, Radek Ampapa, Michael Barnett, Jan Hillert, Freek Verheul, Maria Trojano, Franco Granella, Edgardo Cristiano, Maria Pia Amato, Dana Horakova, Alessandra Lugaresi, Celia Oreja-Guevara, Steve Vucic, Eva Havrdova, Tim Spelman, Javier Olascoaga, Kalincik, Toma, Manouchehrinia, Ali, Sobisek, Luka, Jokubaitis, Vilija, Spelman, Tim, Horakova, Dana, Havrdova, Eva, Trojano, Maria, Izquierdo, Guillermo, Lugaresi, Alessandra, Girard, Marc, Prat, Alexandre, Duquette, Pierre, Grammond, Pierre, Sola, Patrizia, Hupperts, Raymond, Grand'Maison, Francoi, Pucci, Eugenio, Boz, Cavit, Alroughani, Raed, Van Pesch, Vincent, Lechner-scott, Jeannette, Terzi, Murat, Bergamaschi, Roberto, Iuliano, Gerardo, Granella, Franco, Spitaleri, Daniele, Shaygannejad, Vahid, Oreja-guevara, Celia, Slee, Mark, Ampapa, Radek, Verheul, Freek, Mccombe, Pamela, Olascoaga, Javier, Amato, Maria Pia, Vucic, Steve, Hodgkinson, Suzanne, Ramo-tello, Cristina, Flechter, Shlomo, Cristiano, Edgardo, Rozsa, Csilla, Moore, Fraser, Sanchez-menoyo, Jose Lui, Saladino, Maria Laura, Barnett, Michael, Hillert, Jan, Butzkueven, Helmut, DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE, OMÜ, [Kalincik, Tomas] Univ Melbourne, CORE, Dept Med, 300 Grattan St, Melbourne, Vic 3050, Australia, [Kalincik, Tomas] Royal Melbourne Hosp, Dept Neurol, 300 Grattan St, Melbourne, Vic 3050, Australia, [Jokubaitis, Vilija] Royal Melbourne Hosp, Dept Neurol, 300 Grattan St, Melbourne, Vic 3050, Australia, [Spelman, Tim] Royal Melbourne Hosp, Dept Neurol, 300 Grattan St, Melbourne, Vic 3050, Australia, [Manouchehrinia, Ali] Karolinska Inst, Dept Clin Neurosci, SE-17177 Stockholm, Sweden, [Sobisek, Lukas] Gen Univ Hosp, Dept Neurol, Katerinska 30, Prague 12808, Czech Republic, [Horakova, Dana] Gen Univ Hosp, Dept Neurol, Katerinska 30, Prague 12808, Czech Republic, [Havrdova, Eva] Gen Univ Hosp, Dept Neurol, Katerinska 30, Prague 12808, Czech Republic, [Sobisek, Lukas] Gen Univ Hosp, Ctr Clin Neurosci, Katerinska 30, Prague 12808, Czech Republic, [Horakova, Dana] Gen Univ Hosp, Ctr Clin Neurosci, Katerinska 30, Prague 12808, Czech Republic, [Havrdova, Eva] Gen Univ Hosp, Ctr Clin Neurosci, Katerinska 30, Prague 12808, Czech Republic, [Sobisek, Lukas] Charles Univ Prague, Katerinska 30, Prague 12808, Czech Republic, [Horakova, Dana] Charles Univ Prague, Katerinska 30, Prague 12808, Czech Republic, [Havrdova, Eva] Charles Univ Prague, Katerinska 30, Prague 12808, Czech Republic, [Sobisek, Lukas] Univ Econ Prague, Dept Stat & Probabil, Winston Churchill Sq 1938-4, Prague 13067, Czech Republic, [Jokubaitis, Vilija] Univ Melbourne, Dept Med, 300 Grattan St, Melbourne, Vic 3050, Australia, [Spelman, Tim] Univ Melbourne, Dept Med, 300 Grattan St, Melbourne, Vic 3050, Australia, [Trojano, Maria] Univ Bari, Via Calefati 53, I-70122 Bari, Italy, [Izquierdo, Guillermo] Hosp Univ Virgen Macarena, Amador De Los Rios 48-50 4a, Seville 41003, Spain, [Lugaresi, Alessandra] Univ G DAnnunzio, Dept Neurosci Imaging & Clin Sci, Via Vestini, I-66100 Chieti, Italy, [Lugaresi, Alessandra] Univ Bologna, Dept Biomed & Neuromotor Sci, Via Vestini, I-66100 Bologna, Italy, [Girard, Marc] Hop Notre Dame De Bon Secours, 1560 Sherbrooke East, Montreal, PQ H2L 4M1, Canada, [Prat, Alexandre] Hop Notre Dame De Bon Secours, 1560 Sherbrooke East, Montreal, PQ H2L 4M1, Canada, [Duquette, Pierre] Hop Notre Dame De Bon Secours, 1560 Sherbrooke East, Montreal, PQ H2L 4M1, Canada, [Girard, Marc] CHUM, Montreal, PQ, Canada, [Prat, Alexandre] CHUM, Montreal, PQ, Canada, [Duquette, Pierre] CHUM, Montreal, PQ, Canada, [Girard, Marc] Univ Montreal, Montreal, PQ, Canada, [Prat, Alexandre] Univ Montreal, Montreal, PQ, Canada, [Duquette, Pierre] Univ Montreal, Montreal, PQ, Canada, [Grammond, Pierre] Univ Montreal, Montreal, PQ, Canada, [Grammond, Pierre] Ctr Readaptat Deficience Phys Chaudiere Appalache, 9500 Blvd Ctr Hosp, Levis, AB G6X 0A1, Canada, [Sola, Patrizia] Nuovo Osped Civile St Agostino Estense, Via Giardini 1355, I-41100 Modena, Italy, [Hupperts, Raymond] Zuyderland Ziekenhuis, Walramstr 23, NL-6131 BK Sittard, Netherlands, [Grand'Maison, Francois] Neuro Rive Sud, 4896 Boul Taschereau,Suite 250, Greenfield Pk, PQ J4V 2J2, Canada, [Pucci, Eugenio] Azienda Sanitaria Unica Reg Marche AV3, Via Santa Lucia 2, I-62100 Macerata, Italy, [Boz, Cavit] Karadeniz Tech Univ, Farabi Hosp, Med Fac, TR-61080 Trabzon, Turkey, [Alroughani, Raed] Amiri Hosp, POB 1661, Kuwait 73767, Kuwait, [Van Pesch, Vincent] Clin Univ St Luc, Ave Hippocrate,10 UCL10-80, BXL-1200 Brussels, Belgium, [Lechner-Scott, Jeannette] Univ Newcastle, Lookout Rd, Newcastle, NSW 2305, Australia, [Terzi, Murat] Ondokuz Mayis Univ, Fac Med, TR-55160 Kurupelit, Turkey, [Bergamaschi, Roberto] C Mondino Natl Neurol Inst, Via Mondino 2, I-27100 Pavia, Italy, [Iuliano, Gerardo] Osped Riuniti Salerno, Via S Leonardo, I-84100 Salerno, Italy, [Granella, Franco] Univ Parma, Via Gramsci 14, I-43100 Parma, Italy, [Spitaleri, Daniele] Azienda Osped Rilievo Nazl San Giuseppe Moscati A, I-83100 Avellino, Italy, [Shaygannejad, Vahid] Isfahan Univ Med Sci, Soffeh St, Esfahan 81744, Iran, [Oreja-Guevara, Celia] Hosp Univ La Paz, Paseo Castellana 261, Madrid 28050, Spain, [Slee, Mark] Flinders Med Ctr, Flinders Dr, Adelaide, SA 5042, Australia, [Ampapa, Radek] Nemocnice Jihlava, Vrchlickeho 59, Jihlava 58633, Czech Republic, [Verheul, Freek] Groene Hart Ziekenhuis, Bleulandweg 10, NL-2800 BB Gouda, Netherlands, [McCombe, Pamela] Royal Brisbane & Womens Hosp, 33 North St, Spring Hill, Qld 4000, Australia, [Olascoaga, Javier] Hosp Donostia, Paseo Begiristain, San Sebastian 20014, Spain, [Amato, Maria Pia] Univ Florence, Viale Morgagni 85, I-50134 Florence, Italy, [Vucic, Steve] Westmead Hosp, Hawkesbury Rd, Sydney, NSW 2145, Australia, [Hodgkinson, Suzanne] Liverpool Hosp, Elizabeth St,21, Liverpool, SA, Australia, [Ramo-Tello, Cristina] Hosp Germans Trias i Pujol, Crtra Canyet S-N, Badalona 8916, Spain, [Flechter, Shlomo] Assaf Harofeh Med Ctr, IL-70100 Zerifin, Israel, [Cristiano, Edgardo] Hosp Italiano Buenos Aires, Guise 1870, RA-1425 Buenos Aires, DF, Argentina, [Rozsa, Csilla] Jahn Ferenc Teaching Hosp, Koves 1, H-1101 Budapest, Hungary, [Moore, Fraser] Jewish Gen Hosp, 3755 Cote St Catherine, Montreal, PQ J7A 4T8, Canada, [Luis Sanchez-Menoyo, Jose] Hosp Galdakao Usansolo, Barrio Labeaga S-N, Galdakao 48660, Spain, [Laura Saladino, Maria] INEBA Inst Neurosci Buenos Aires, Guardia Vieja 4435,C1192AAW, Buenos Aires, DF, Argentina, [Hillert, Jan] Univ Sydney, Brain & Mind Ctr, 100 Mallett, Camperdown, NSW 2050, Australia, [Butzkueven, Helmut] Monash Univ, Box Hill Hosp, Dept Neurol, Melbourne, Vic, Australia, National Health and Medical Research Council, National Health and Medical Research Council (centre for research excellence), University of Melbourne (Faculty of Medicine, Dentistry and Health Sciences research fellowship), Biogen, Novartis, Merck, Roche, Teva, Sanofi Genzyme, Klinische Neurowetenschappen, MUMC+: MA Med Staf Spec Neurologie (9), and RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience
Subjects: Male, 0301 basic medicine, relapses, Databases, Factual, Failure, disability, multiple sclerosis, precision medicine, prediction, Disability Evaluation, Glatiramer acetate, 0302 clinical medicine, Natalizumab, Recurrence, Risk Factors, Medicine, Relapse, Progression, Precision medicine, Switch, Prognosis, Clinical Trial, Fingolimod, Multicenter Study, Treatment Outcome, Cohort, Disease Progression, Female, Algorithms, Immunosuppressive Agents, medicine.drug, Cohort study, Adult, Registry, medicine.medical_specialty, Multiple Sclerosis, Interferon-beta therapy, External validity, Disability, Multiple sclerosis, Prediction, Relapses, Neurology (clinical), Databases, Young Adult, 03 medical and health sciences, Internal medicine, Journal Article, Humans, Multiple sclerosi, Internal validity, Factual, Disease burden, Demography, business.industry, Prognostic-factors, Reproducibility of Results, Discontinuation, 030104 developmental biology, Physical therapy, business, 030217 neurology & neurosurgery, Forecasting
Abstract: none 47 si Timely initiation of effective therapy is crucial for preventing disability in multiple sclerosis; however, treatment response varies greatly among patients. Comprehensive predictive models of individual treatment response are lacking. Our aims were: (i) to develop predictive algorithms for individual treatment response using demographic, clinical and paraclinical predictors in patients with multiple sclerosis; and (ii) to evaluate accuracy, and internal and external validity of these algorithms. This study evaluated 27 demographic, clinical and paraclinical predictors of individual response to seven disease-modifying therapies in MSBase, a large global cohort study. Treatment response was analysed separately for disability progression, disability regression, relapse frequency, conversion to secondary progressive disease, change in the cumulative disease burden, and the probability of treatment discontinuation. Multivariable survival and generalized linear models were used, together with the principal component analysis to reduce model dimensionality and prevent overparameterization. Accuracy of the individual prediction was tested and its internal validity was evaluated in a separate, non-overlapping cohort. External validity was evaluated in a geographically distinct cohort, the Swedish Multiple Sclerosis Registry. In the training cohort (n = 8513), the most prominent modifiers of treatment response comprised age, disease duration, disease course, previous relapse activity, disability, predominant relapse phenotype and previous therapy. Importantly, the magnitude and direction of the associations varied among therapies and disease outcomes. Higher probability of disability progression during treatment with injectable therapies was predominantly associated with a greater disability at treatment start and the previous therapy. For fingolimod, natalizumab or mitoxantrone, it was mainly associated with lower pretreatment relapse activity. The probability of disability regression was predominantly associated with pre-baseline disability, therapy and relapse activity. Relapse incidence was associated with pretreatment relapse activity, age and relapsing disease course, with the strength of these associations varying among therapies. Accuracy and internal validity (n = 1196) of the resulting predictive models was high (480%) for relapse incidence during the first year and for disability outcomes, moderate for relapse incidence in Years 2-4 and for the change in the cumulative disease burden, and low for conversion to secondary progressive disease and treatment discontinuation. External validation showed similar results, demonstrating high external validity for disability and relapse outcomes, moderate external validity for cumulative disease burden and low external validity for conversion to secondary progressive disease and treatment discontinuation. We conclude that demographic, clinical and paraclinical information helps predict individual response to disease-modifying therapies at the time of their commencement. none Kalincik, Tomas; Manouchehrinia, Ali; Sobisek, Lukas; Jokubaitis, Vilija; Spelman, Tim; Horakova, Dana; Havrdova, Eva; Trojano, Maria; Izquierdo, Guillermo; Lugaresi, Alessandra; Girard, Marc; Prat, Alexandre; Duquette, Pierre; Grammond, Pierre; Sola, Patrizia; Hupperts, Raymond; Grand'Maison, Francois; Pucci, Eugenio; Boz, Cavit; Alroughani, Raed; Van Pesch, Vincent; Lechner-scott, Jeannette; Terzi, Murat; Bergamaschi, Roberto; Iuliano, Gerardo; Granella, Franco; Spitaleri, Daniele; Shaygannejad, Vahid; Oreja-guevara, Celia; Slee, Mark; Ampapa, Radek; Verheul, Freek; Mccombe, Pamela; Olascoaga, Javier; Amato, Maria Pia; Vucic, Steve; Hodgkinson, Suzanne; Ramo-tello, Cristina; Flechter, Shlomo; Cristiano, Edgardo; Rozsa, Csilla; Moore, Fraser; Sanchez-menoyo, Jose Luis; Saladino, Maria Laura; Barnett, Michael; Hillert, Jan; Butzkueven, Helmut Kalincik, Tomas; Manouchehrinia, Ali; Sobisek, Lukas; Jokubaitis, Vilija; Spelman, Tim; Horakova, Dana; Havrdova, Eva; Trojano, Maria; Izquierdo, Guillermo; Lugaresi, Alessandra; Girard, Marc; Prat, Alexandre; Duquette, Pierre; Grammond, Pierre; Sola, Patrizia; Hupperts, Raymond; Grand'Maison, Francois; Pucci, Eugenio; Boz, Cavit; Alroughani, Raed; Van Pesch, Vincent; Lechner-scott, Jeannette; Terzi, Murat; Bergamaschi, Roberto; Iuliano, Gerardo; Granella, Franco; Spitaleri, Daniele; Shaygannejad, Vahid; Oreja-guevara, Celia; Slee, Mark; Ampapa, Radek; Verheul, Freek; Mccombe, Pamela; Olascoaga, Javier; Amato, Maria Pia; Vucic, Steve; Hodgkinson, Suzanne; Ramo-tello, Cristina; Flechter, Shlomo; Cristiano, Edgardo; Rozsa, Csilla; Moore, Fraser; Sanchez-menoyo, Jose Luis; Saladino, Maria Laura; Barnett, Michael; Hillert, Jan; Butzkueven, Helmut
Published: 2017

47. Liu estimator in partly linear regression models with correlated errors

Author: M. Revan Özkale, Gülin Tabakan, Çukurova Üniversitesi, [Tabakan, Gulin] Aksaray Univ, Dept Math, TR-68100 Aksaray, Turkey -- [Ozkale, M. Revan] Cukurova Univ, Dept Stat, Adana, Turkey, Ozkale, M.Revan -- 0000-0001-7085-7403, and İktisadi ve İdari Bilimler Fakültesi
Subjects: Statistics and Probability, Partly linear models, Mean squared error, Liu Sstimator, Liu estimator, Linear model, Estimator, 010103 numerical & computational mathematics, Trimmed estimator, 01 natural sciences, Least squares, 010104 statistics & probability, Minimum-variance unbiased estimator, Efficient estimator, Multicollinearity, Modeling and Simulation, Ordinary least squares, Statistics, Ridge estimator, 0101 mathematics, Smoothing parameter, Mathematics
Abstract: WOS: 000398114600022, This article is concerned with the parameter estimation in partly linear regression models when the errors are dependent. To overcome the multicollinearity problem, a generalized Liu estimator is proposed. The theoretical properties of the proposed estimator and its relationship with some existing methods designed for partly linear models are investigated. Finally, a hypothetical data is conducted to illustrate some of the theoretical results.
Published: 2017

48. ON THE EXISTENCE OF epsilon-OPTIMAL TRAJECTORIES OF THE CONTROL SYSTEMS WITH CONSTRAINED CONTROL RESOURCES

Author: Huseyin, Anar and [Huseyin, Anar] Cumhuriyet Univ, Fac Sci, Dept Stat, TR-58140 Sivas, Turkey
Subjects: set of trajectories, epsilon-optimal trajectory, control system, Urysohn integral equation, integral constraint
Abstract: WOS: 000407115700007, The control system described by a Urysohn type integral equation is considered. It is assumed that the admissible control functions are chosen from the closed ball of the space L-p, p > 1, with radius r and centered at the origin. Precompactness of the set of trajectories of the control system in the space of continuous functions is shown. This allows to prove that optimal control problem with lower semicontinuous payoff functional has an epsilon-optimal trajectory for every epsilon > 0.
Published: 2017

49. Sub-Manifolds of a Riemannian Manifold

Author: Atceken, Mehmet, Yildirim, Umit, Dirik, Suleyman, Bracken, P, and [Atceken, Mehmet -- Yildirim, Umit] Gaziosmanpasa Univ, Dept Math, Fac Arts & Sci, Tokat, Turkey -- [Dirik, Suleyman] Amasya Univ, Dept Stat, Fac Arts & Sci, Amasya, Turkey
Subjects: real product space forms, a distribution on a manifold, Riemannian product structure, integral manifold, Mathematics::Differential Geometry, Riemannian product manifold, Mathematics::Geometric Topology, Mathematics::Symplectic Geometry, a slant distribution
Abstract: WOS: 000411974300004 In this chapter, we introduce the theory of sub-manifolds of a Riemannian manifold. The fundamental notations are given. The theory of sub-manifolds of an almost Riemannian product manifold is one of the most interesting topics in differential geometry. According to the behaviour of the tangent bundle of a sub-manifold, with respect to the action of almost Riemannian product structure of the ambient manifolds, we have three typical classes of sub-manifolds such as invariant sub-manifolds, anti-invariant sub-manifolds and semi-invariant sub-manifolds. In addition, slant, semi-slant and pseudo-slant sub-manifolds are introduced by many geometers.
Published: 2017

50. Semiparallel Submanifolds of a Normal Paracontact Metric Manifold

Author: Mehmet Atçeken, Süleyman Dirik, Ümit Yildirim, Gaziosmanpaşa Üniversitesi, 0-Belirlenecek, and [Atceken, Mehmet -- Yildirim, Umit] Gaziosmanpasa Univ, Fac Arts & Sci, Dept Math, Tokat, Turkey -- [Dirik, Suleyman] Amasya Univ, Fac Arts & Sci, Dept Stat, Amasya, Turkey
Subjects: concircular curvature tensor, Pure mathematics, Matematik, invariant submanifold, Riemannian curvature tensor,concircular curvature tensor,invariant submanifold,semiparallel and 2-semiparallel submanifolds, General Medicine, Riemannian curvature tensor, semiparallel and 2-semiparallel submanifolds, Totally geodesic, İstatistik ve Olasılık, Mathematics::Differential Geometry, Invariant (mathematics), Mathematics::Symplectic Geometry, Mathematics
Abstract: WOS: 000464826600016 The object of the present paper is to study invariant semiparallel and 2-semiparallel submanifolds of a normal paracontact metric manifold. We see that parallel submanifolds of a normal paracontact metric manifold are totally geodesic.
Published: 2016

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Journal

Database

Publisher

82 results on '"Dept Stat"'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources