1. Radiation therapy at compact Compton sources
- Author
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Pekka Suortti, Marie Jacquet, Dept. Accelerateurs, Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Univ. of Helsinki, Dept. of Physics, ThomX, and Department of Physics
- Subjects
Photon ,Technology Assessment, Biomedical ,ThomX ,[PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph] ,Biophysics ,General Physics and Astronomy ,Synchrotron radiation ,Electron ,Radiation ,Physics and Astronomy(all) ,Linear particle accelerator ,law.invention ,SYNCHROTRON-RADIATION ,Radiotherapy, High-Energy ,Optics ,law ,X-rays ,Animals ,Humans ,COMPUTED-TOMOGRAPHY ,Radiology, Nuclear Medicine and imaging ,[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,Physics ,Miniaturization ,Interaction point ,business.industry ,General Medicine ,Equipment Design ,Compton source ,3126 Surgery, anesthesiology, intensive care, radiology ,Laser ,Equipment Failure Analysis ,Radiation therapy ,Radiology Nuclear Medicine and imaging ,Physics::Accelerator Physics ,Dose Fractionation, Radiation ,Atomic physics ,business ,Storage ring ,Synchrotrons - Abstract
The principle of the compact Compton source is presented briefly. In collision with an ultrarelativistic electron bunch a laser pulse is back-scattered as hard X-rays. The radiation cone has an opening of a few mrad, and the energy bandwidth is a few percent. The electrons that have an energy of the order of a few tens of MeV either circulate in storage ring, or are injected to a linac at a frequency of 10-100 MHz. At the interaction point the electron bunch collides with the laser pulse that has been amplified in a Fabry-Perot resonator. There are several machines in design or construction phase, and projected fluxes are 1012 to 10(14) photons/s. The flux available at 80 keV from the ThomX machine is compared with that used in the Stereotactic Synchrotron Radiation Therapy clinical trials. It is concluded that ThomX has the potential of serving as the radiation source in future radiation therapy programs, and that ThomX can be integrated in hospital environment. (C) 2015 Published by Elsevier Ltd on behalf of Associazione Italiana di Fisica Medica.
- Published
- 2015
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