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279 results on '"Dequanter, Didier"'

5. Patient-reported outcomes in terms of swallowing and quality of life after prophylactic versus reactive percutaneous endoscopic gastrostomy tube placement in advanced oropharyngeal cancer patients treated with definitive chemo-radiotherapy: Swall PEG study

Author

Dragan, Tatiana, Van Gossum, André, Duprez, Frederic, Lalami, Yassine, Lefebvre, Yolene, Mootassim-Billah, Sofiana, Beauvois, Sylvie, Gulyban, Akos, Vandekerkhove, Christophe, Boegner, Petra, Paesmans, Marianne, Ameye, Lieveke, Digonnet, Antoine, Quiriny, Marie, Dequanter, Didier, Lipski, Samuel, Willemse, Esther, Rodriguez, Alejandra, Carlot, Sebastien, Karaca, Yasemin, Lemort, Marc, Emonts, Patrick, Al Wardi, Clémence, and Van Gestel, Dirk

Published
2022
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6. Features of Mild-to-Moderate COVID-19 Patients With Dysphonia

Author

Lechien, Jerome R., Chiesa-Estomba, Carlos M., Cabaraux, Pierre, Mat, Quentin, Huet, Kathy, Harmegnies, Bernard, Horoi, Mihaela, Le Bon, Serge Daniel, Rodriguez, Alexandra, Dequanter, Didier, Hans, Stéphane, Crevier-Buchman, Lise, Hochet, Baptiste, Distinguin, Lea, Chekkoury-Idrissi, Younes, Circiu, Marta, El Afia, Fahd, Barillari, Maria Rosaria, Cammaroto, Giovanni, Fakhry, Nicolas, Michel, Justin, Radulesco, Thomas, Martiny, Delphine, Lavigne, Philippe, Jouffe, Lionel, Descamps, Géraldine, Journe, Fabrice, Trecca, Eleonora M.C., Hsieh, Julien, Delgado, Irene Lopez, Calvo-Henriquez, Christian, Vergez, Sebastien, Khalife, Mohamad, Molteni, Gabriele, Mannelli, Giuditta, Cantarella, Giovanna, Tucciarone, Manuel, Souchay, Christel, Leich, Pierre, Ayad, Tareck, and Saussez, Sven

Published
2022
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7. Treatment of medication-related osteonecrosis of the jaw with cell therapy

Author

Bouland, Cyril Lucien, primary, Javadian, Rokneddine, additional, Gilis, Sarah, additional, Yanni, Antoine, additional, Le Clercq, Maxime, additional, Mestrallet, Pierre, additional, Kampouridis, Stelianos, additional, Bron, Dominique, additional, Lalmand, Martin, additional, Vanden Eynden, Xavier, additional, Boutremans, Edward, additional, Dequanter, Didier, additional, Loeb, Isabelle, additional, Philippart, Pierre, additional, Lagneaux, Laurence, additional, and Meuleman, Nathalie, additional

Published
2024
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9. Validity and reliability of the Group for Learning Useful and Performant Swallowing (GLUPS) tool

Author

Lechien, Jerome R., primary, Blouin, Auriane, additional, Baudouin, Robin, additional, Bousard, Laura, additional, Rodriguez, Alexandra, additional, Verhasselt, Marie, additional, Cavelier, Gaetan, additional, Vialatte de Pemille, Grégoire, additional, Circiu, Marta P., additional, Crevier-Buchman, Lise, additional, Hans, Stephane, additional, Vanderwegen, Jan, additional, and Dequanter, Didier, additional

Published
2023
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13. Preventive and Therapeutic Effect of Metformin in Head and Neck Cancer: A Concise Review

Author

Bouland, Cyril, primary, Vanden Eynden, Xavier, additional, Lalmand, Martin, additional, Buset, Thibaut, additional, Yanni, Antoine, additional, Javadian, Rokneddine, additional, Rodriguez, Alexandra, additional, Loeb, Isabelle, additional, Lechien, Jérôme R., additional, Journe, Fabrice, additional, Saussez, Sven, additional, and Dequanter, Didier, additional

Published
2023
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16. Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux

Author

Lechien, Jerome R., Bobin, Francois, Mouawad, Francois, Zelenik, Karol, Calvo-Henriquez, Christian, Chiesa-Estomba, Carlos M., Enver, Necati, Nacci, Andrea, Barillari, Maria Rosaria, Schindler, Antonio, Crevier-Buchman, Lise, Hans, Stéphane, Simeone, Virginie, Wlodarczyk, Elzbieta, Harmegnies, Bernard, Remacle, Marc, Rodriguez, Alexandra, Dequanter, Didier, Eisendrath, Pierre, Dapri, Giovanni, Finck, Camille, Karkos, Petros, Pendleton, Hillevi, Ayad, Tareck, Muls, Vinciane, and Saussez, Sven

Published
2019
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27. Impact of Acid, Weakly Acid and Alkaline Laryngopharyngeal Reflux on Voice Quality

Author

Lechien, Jerome R., primary, Carroll, Thomas L., additional, Nowak, Géraldine, additional, Huet, Kathy, additional, Harmegnies, Bernard, additional, Lechien, Alain, additional, Horoi, Mihaela, additional, Dequanter, Didier, additional, Bon, Serge D. Le, additional, Saussez, Sven, additional, Hans, Stéphane, additional, and Rodriguez, Alexandra, additional

Published
2021
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28. Prognostic Significance of a Scoring System Combining p16, Smoking, and Drinking Status in a Series of 131 Patients with Oropharyngeal Cancers

Author

Bouland, Cyril, primary, Dequanter, Didier, additional, Lechien, Jérôme R., additional, Hanssens, Charlotte, additional, De Saint Aubain, Nicolas, additional, Digonnet, Antoine, additional, Javadian, Rokneddine, additional, Yanni, Antoine, additional, Rodriguez, Alexandra, additional, Loeb, Isabelle, additional, Journe, Fabrice, additional, and Saussez, Sven, additional

Published
2021
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29. Contribution of antiangiogenic agents to the risk of medication-related osteonecrosis of the jaw in combination with antiresorptive agents: Preliminary results in a comparative prospective report of 59 oncologic cases.

Author

Yanni, Antoine, Bouland, Cyril, Monteiro, Raquel, Rodriguez, Alexandra, Loeb, Isabelle, Javadian, Rokneddine, and Dequanter, Didier

Subjects
NEOVASCULARIZATION inhibitors, OSTEONECROSIS, STATISTICAL software, TOBACCO use, JAWS
Abstract

Aim: The aim of this preliminary study was to evaluate in an oncological population the association risk of antiangiogenic (AA) agents to antiresorptive (AR) agents on the incidence and the severity of medication-related osteonecrosis of the jaw (MRONJ). Materials and Methods: In this prospective study, we reviewed the medical records and clinical variables of 59 consecutive oncologic patients who developed MRONJ. For all patients, we retrieved the following variables: age, gender, alcohol and tobacco use, type of cancer, use of corticosteroids for >3 months, history of diabetes, MRONJ staging, combination of AR and AA agents, dental history (surgery, prosthesis) or spontaneous, site of MRONJ, delay between AR and AA first intake, and MRONJ development. Patients were divided into two groups according to drugs therapy they underwent: group 1 (G1) including patients treated with AR agents alone and group 2 (G2) including patients receiving antiresorptive–antiangiogenic drugs (AR+AA). The degree and the therapeutical success were defined as primary outcomes and the number, the localization, and the delay in onset of the lesions as secondary outcomes. In order to identify predictive factors of osteonecrosis-free interval time, univariate and multivariate Cox regression was performed. Statistical tests were carried out using the IBM® SPSS® Statistics software. All reported P-values are two-tailed and were considered to be significant when less than 0.05. Results: Among the 47 patients who received AR agent alone (group 1), the mean treatment duration before diagnosis of MRONJ was 39.2 months. In the second group (n = 12), patients developed MRONJ with a comparable mean time of 55 months (P = 0.16). According to the staging of MRONJ at the time of diagnosis, no significant difference (P = 0.736) was observed between the two groups. Moreover, the treatment applied was not statistically different in both the groups and was successful in 36.17% of the patients in group 1 and 58.33% of the patients in group 2. No statistically difference was reported in both the groups (P = 0.16). After statistical analysis, no significant difference in terms of MRONJ localization (P = 0.13) was observed. Finally, the incidence of spontaneous MRONJ was comparable in both the groups. Statistical analysis revealed that total time of treatment was the only factor associated with poor osteonecrosis-free interval time (hazard ratio 0.99; P = 0.001). Interestingly, the combination of an AA and AR agent was not a significant predictor factor of the interval time before the diagnosis of osteonecrosis. Additionally, corticosteroid use, diabetes mellitus, and dental consultation before treatment were not statistically related to poorer osteonecrosis-free interval time rates. Conclusion: In our preliminary study, neither the mean treatment time duration before the diagnosis of MRONJ nor the dose delivered was different in both the groups (AR vs. AR+AA). Moreover, no significant difference was observed between both the groups regarding the localization and the staging of MRONJ at the time of diagnosis. Interestingly, our results demonstrated that the risk of spontaneous MRONJ is statistically comparable in the AR and AR–AA groups. Additionally, the addition of an AA agent did not influence the treatment applied in the two groups of patients. [ABSTRACT FROM AUTHOR]

Published
2022
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35. The efficacy of a personalised treatment depending on the characteristics of reflux at multichannel intraluminal impedance‐pH monitoring in patients with acid, non‐acid and mixed laryngopharyngeal reflux

Author

Lechien, Jérôme R., primary, Bobin, Francois, additional, Muls, Vinciane, additional, Mouawad, Francois, additional, Dequanter, Didier, additional, Horoi, Mihaela, additional, Thill, Marie‐Paule, additional, Rodriguez Ruiz, Alexandra, additional, and Saussez, Sven, additional

Published
2021
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37. Clinical and histopathological risk factors for distant metastasis in head and neck cancer patients

Author

Chiesa-Estomba, Carlos Miguel, primary, Lechien, Jerome R., additional, Ayad, Tareck, additional, Calvo-Henriquez, Christian, additional, González-García, José Ángel, additional, Sistiaga-Suarez, Jon Alexander, additional, Dequanter, Didier, additional, Fakhry, Nicolas, additional, Melesse, Gebeyehu, additional, and Piazza, Cesare, additional

Published
2021
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38. Influence of Age and Sex on Clinical and Therapeutic Features of Laryngopharyngeal Reflux.

Author

Lechien, Jerome R., Carroll, Thomas L., Bobin, Francois, Muls, Vinciane, Rodriguez, Alexandra, Horoi, Mihaela, Dequanter, Didier, Crevier-Buchman, Lise, Hans, Stéphane, and Saussez, Sven

Abstract

Objective: To explore the influence of age and sex on the clinical presentation and therapeutic response of patients with laryngopharyngeal reflux (LPR). Study Design: Prospective study. Setting: Prospective multicenter study of 271 patients with a diagnosis of LPR confirmed by impedance-pH monitoring. Methods: Patients were prescribed 6 months of diet changes and a combination of pantoprazole and/or alginate depending on the results of their impedance-pH results. The Reflux Symptom Score (RSS) and Reflux Sign Assessment (RSA) were collected at baseline and at 3 and 6 months posttreatment. Data were explored according to sex and age. Results: A total of 237 patients completed the evaluations (138 females). On the RSS, patients of the oldest group (>60 years) had lower symptom scores (throat pain, ear pain, odynophagia, chest pain, tongue burning, nausea, halitosis, and indigestion) and lower quality-of-life scores than younger individuals. RSS and RSA outcomes significantly improved from pretreatment to 3 months posttreatment in all groups. Scores on the RSS and RSA continued to improve from 3 to 6 months posttreatment in the elderly group. Females with LPR had a higher score on the RSS at baseline as compared with males. On the RSS, scores significantly improved after 3 months in males and females; however, they continued to improve from 3 to 6 months in the female group. Conclusion: Age and sex may influence the clinical presentation and pre- to posttreatment evolution of symptoms and findings. Age and sex differences could be considered in future therapeutic approaches to guide more effective personalized treatment plans for patients with LPR. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Clinical and epidemiological characteristics of 1420 European patients with mild‐to‐moderate coronavirus disease 2019

Author

Lechien, Jerome R., Chiesa‐Estomba, Carlos M., Place, Sammy, Van Laethem, Yves, Cabaraux, Pierre, Mat, Quentin, Huet, Kathy, Plzak, Jan, Horoi, Mihaela, Hans, Stéphane, Rosaria Barillari, Maria, Cammaroto, Giovanni, Fakhry, Nicolas, Martiny, Delphine, Ayad, Tareck, Jouffe, Lionel, Hopkins, Claire, Saussez, Sven, Blecic, Serge, De Siati, Daniele R., Leich, Pierre, Souchay, Christel, Rossi, Camelia, Journe, Fabrice, Hsieh, Julien, Ris, Laurence, El Afia, Fahd, Harmegnies, Bernard, Distinguin, Lea, Chekkoury‐Idrissi, Younes, Circiu, Marta, Lavigne, Philippe, Lopez Delgado, Irene, Calvo‐Henriquez, Christian, Falanga, Chiara, Coppee, Frederique, Le Bon, Serge Daniel, Rodriguez, Alexandra, Dequanter, Didier, Cornelis, Jean‐Philippe, Vergez, Sebastien, Koenen, Lukas, Giuditta, Mannelli, Molteni, Gabriele, Tucciarone, Manuel, Radulesco, Thomas, Khalife, Mohamad, Fourneau, Anne‐Francoise, Cherifi, Soraya, Manto, Mario, Michel, Justin, Mannelli, Giuditta, Cantarella, Giovanna, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Assistance Publique - Hôpitaux de Marseille (APHM), Laboratoire Parole et Langage (LPL), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), We would like to thank Bayesia (BayesiaLab?, Chang?, France) for the Network Analysis, Jean-Louis Vincent and Michel Van Haeverbeek for the review of the paper or their useful comments, the heads of the Hospitals, which have been involved in the study, for their help in the rapid conduction of the study and the agreement of ethics committees, the European Press/Media (i.e. Le Monde, La Libre, Le Soir, MediQuality, MedScape, and Le Specialiste) for their help in the spread of the information about the study, and FRMH & UMONS for the grant and the support., Lechien, J. R., Chiesa-Estomba, C. M., Place, S., Van Laethem, Y., Cabaraux, P., Mat, Q., Huet, K., Plzak, J., Horoi, M., Hans, S., Barillari, M. R., Cammaroto, G., Fakhry, N., Martiny, D., Ayad, T., Jouffe, L., Hopkins, C., Saussez, S., Blecic, S., De Siati, D. R., Leich, P., Souchay, C., Rossi, C., Journe, F., Hsieh, J., Ris, L., El Afia, F., Harmegnies, B., Distinguin, L., Chekkoury-Idrissi, Y., Circiu, M., Lavigne, P., Lopez Delgado, I., Calvo-Henriquez, C., Falanga, C., Coppee, F., Le Bon, S. D., Rodriguez, A., Dequanter, D., Cornelis, J. -P., Vergez, S., Koenen, L., Giuditta, M., Molteni, G., Tucciarone, M., Radulesco, T., Khalife, M., Fourneau, A. -F., Cherifi, S., Manto, M., Michel, J., Mannelli, G., and Cantarella, G.

Subjects
0301 basic medicine, myalgia, Male, medicine, Original, [SDV]Life Sciences [q-bio], coronavirus, symptoms, Disease, epidemiological, 030204 cardiovascular system & hematology, patients, clinical, Olfaction Disorders, Taste Disorders, 0302 clinical medicine, Epidemiology, Sore throat, Prevalence, Nose, Age Factors, Headache, Middle Aged, 3. Good health, Europe, medicine.anatomical_structure, COVID-19, Female, patient, medicine.symptom, Symptom Assessment, Coronavirus Infections, Sex characteristics, Adult, medicine.medical_specialty, Pneumonia, Viral, 03 medical and health sciences, Betacoronavirus, Sex Factors, Throat, Internal medicine, Internal Medicine, Humans, Pandemics, covid‐19, rhinorrhea, business.industry, SARS-CoV-2, Bayes Theorem, Myalgia, coronaviru, 030104 developmental biology, business
Abstract

International audience; Background: The clinical presentation of European patients with mild-to-moderate COVID-19 infection is still unknown. Objective: To study the clinical presentation of COVID-19 in Europe. Methods: Patients with positive diagnosis of COVID-19 were recruited from 18 European hospitals. Epidemiological and clinical data were obtained through a standardized questionnaire. Bayesian analysis was used for analysing the relationship between outcomes. Results: A total of 1,420 patients completed the study (962 females, 30.7% of healthcare workers). The mean age of patients was 39.17 ± 12.09 years. The most common symptoms were headache (70.3%), loss of smell (70.2%), nasal obstruction (67.8%), cough (63.2%), asthenia (63.3%), myalgia (62.5%), rhinorrhea (60.1%), gustatory dysfunction (54.2%) and sore throat (52.9%). Fever was reported by 45.4%. The mean duration of COVID-19 symptoms of mild-to-moderate cured patients was 11.5 ± 5.7 days. The prevalence of symptoms significantly varied according to age and sex. Young patients more frequently had ear, nose and throat complaints, whereas elderly individuals often presented fever, fatigue and loss of appetite. Loss of smell, headache, nasal obstruction and fatigue were more prevalent in female patients. The loss of smell was a key symptom of mild-to-moderate COVID-19 patients and was not associated with nasal obstruction and rhinorrhea. Loss of smell persisted at least 7 days after the disease in 37.5% of cured patients. Conclusion: The clinical presentation of mild-to-moderate COVID-19 substantially varies according to the age and the sex characteristics of patients. Olfactory dysfunction seems to be an important underestimated symptom of mild-to-moderate COVID-19 that needs to be recognized as such by the WHO.

Published
2020
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43. An Unusual Case of Primary Hyperparathyroidism: Case Report of a Bifocal Intrathyroidal Parathyroid Carcinoma.

Author

Damien, Maxime, Rodriguez, Alexandra, Kleynen, Pierre, Dequanter, Didier, and Bouland, Cyril

Subjects
NECK physiology, HYPERCALCEMIA, THYROIDECTOMY, ULTRASONIC imaging, THYROID gland tumors, ADRENALECTOMY, METHIONINE, HYPERPARATHYROIDISM, PARATHYROID gland tumors, RADIOPHARMACEUTICALS, COMPUTED tomography, DISEASE complications
Abstract

Intrathyroidal parathyroid carcinoma is an extremely rare cause of primary hyperparathyroidism. We reported a 51-year old woman who presented symptoms of hypercalcemia. 99mTc sestamibi single-photon emission computed tomography/computed tomography (CT) revealed a large hypermetabolic nodule in the left thyroid lobe suggestive of hyperfunctioning parathyroid tissue. 11C-methionine positron emission tomography/computed tomography (PET/CT) and 18F-fluorocholine PET/CT confirmed the nodule in the left thyroid lobe and also revealed a hypermetabolic activity on the posterior surface of the lower left pole. The patient underwent a total thyroidectomy and parathyroidectomy, and a diagnosis of bifocal intrathyroidal parathyroid carcinoma was confirmed. We present the first reported case of bifocal intrathyroidal carcinoma and discuss the discordant imaging results. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Psychophysical evaluation of chemosensory functions 5 weeks after olfactory loss due to COVID-19: a prospective cohort study on 72 patients

Author

Le Bon, Serge-Daniel, primary, Pisarski, Nathalie, additional, Verbeke, Justine, additional, Prunier, Léa, additional, Cavelier, Gaëtan, additional, Thill, Marie-Paule, additional, Rodriguez, Alexandra, additional, Dequanter, Didier, additional, Lechien, Jérôme R., additional, Le Bon, Olivier, additional, Hummel, Thomas, additional, and Horoi, Mihaela, additional

Published
2020
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46. Implications of a positive sentinel node in oral squamous cell carcinoma

Author

Gurney, Benjamin A. S., Schilling, Clare, Putcha, Venkata, Alkureishi, Lee W., Alvarez, Amezaga J., Bakholdt, Vivi, Barbier Herrero, Luis, Barzan, Luigi, Bilde, Anders, Bloemena, Elisabeth, Salces, Carmen Camarero, Palma, Paolo Dalla, de Bree, Remco, Dequanter, Didier, Dolivet, Gilles, Donner, Davide, Flach, Geke B., Fresno, Manuel, Grandi, Cesare, Haerle, Stephan, Huber, Gerhard F., Hunter, Keith, Lawson, George, Leroux, Agnes, Lothaire, Phillippe H., Mamelle, Gerard, Silini, Enrico M., Mastronicola, Romina, Odell, Edward W., OʼDoherty, Michael J., Poli, Tito, Rahimi, Siavash, Ross, Gary L., Zuazua, Santamaria J., Santini, Simone, Sebbesen, Lars, Shoaib, Taimur, Sloan, Philip, Sorensen, Jens Ahm, Soutar, David S., Therkildsen, Marianne H., Vigili, Maurizio Giovanni, Villarreal, Pedro M., von Buchwald, Christian, Werner, Jochen A., Wiegand, Susanne, and McGurk, Mark

Published
2012
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50. Hypopharyngeal‐Esophageal Impedance‐pH Monitoring Profiles of Laryngopharyngeal Reflux Patients

Author

Lechien, Jerome R., primary, Bobin, Francois, additional, Dapri, Giovanni, additional, Eisendrath, Pierre, additional, Salem, Charelle, additional, Mouawad, Francois, additional, Horoi, Mihaela, additional, Thill, Marie‐Paule, additional, Dequanter, Didier, additional, Rodriguez, Alexandra, additional, Muls, Vinciane, additional, and Saussez, Sven, additional

Published
2020
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