1. Development of a core outcome set for effectiveness trials aimed at optimising prescribing in older adults in care homes
- Author
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Millar, AN, Daffu-O'Reilly, A, Hughes, C, Alldred, DP, Barton, G, Bond, CM, Desborough, JA, Myint, P, Holland, R, Poland, F, and Wright, D
- Subjects
Optimising prescribing ,Clinical Trials as Topic ,Consensus ,Delphi Technique ,Medication Therapy Management ,Research ,Core outcome set ,Care homes ,Community Pharmacy Services ,Drug Prescriptions ,Medicines Optimisation ,Nursing Homes ,Research Design ,Older adults ,Practice Guidelines as Topic ,Homes for the Aged ,Humans ,Interdisciplinary Communication ,COS ,Guideline Adherence ,Prospective Studies ,Practice Patterns, Physicians' ,CHIPPS - Abstract
Background: Prescribing medicines for older adults in care homes is known to be sub-optimal. Whilst trials testing interventions to optimise prescribing in this setting have been published, heterogeneity in outcome reporting has hindered comparison of interventions, thus limiting evidence synthesis. The aim of this study was to develop a core outcome set (COS), a list of outcomes which should be measured and reported, as a minimum, for all effectiveness trials involving optimising prescribing in care homes. The COS was developed as part of the Care Homes Independent Pharmacist Prescribing Study (CHIPPS). Methods: A long-list of outcomes was identified through a review of published literature and stakeholder input. Outcomes were reviewed and refined prior to entering a two-round online Delphi exercise and then distributed via a web link to the CHIPPS Management Team, a multidisciplinary team including pharmacists, doctors and Patient Public Involvement representatives (amongst others), who comprised the Delphi panel. The Delphi panellists (n = 19) rated the importance of outcomes on a 9-point Likert scale from 1 (not important) to 9 (critically important). Consensus for an outcome being included in the COS was defined as ≥70% participants scoring 7–9 and
- Published
- 2017