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19 results on '"Di Ciaccio, Paola"'

1. Santander Statement: Towards Global Convergence in Transplantation: Sufficiency, Transparency, and Oversight

Author

Adamec, Milos, Ahn, Curie, Albreht, Katarina, Almén, Helena, Al Obaidli, Ali Abdul Kareem, Anušić Juričić, Martina, Arrabal, Samuel, Ascher, Nancy, Ashkenazi, Tamar, Avendaño-Solá, Cristina, Avsec, Danica, Badenes, Rafael, Bal, Omer, Ballesté, Chloë, Barquero, Teresita, Be, Alicia, Beltrán, Mauricio, Bengochea, Milka, Beqo, Flutra, Berenguer, Marina, Berishvili, Ekaterina, Bokhorst, Arlinke, Boletis, Ioannis, Bolocan, Vladimir, Koh, Mickey BC, Börgel, Martin, Briceño, Javier, Brix-Zuleger, Martina, Busic, Mirela, Buziuviene, Audrone, Caballero, Xavier, Caamaño, Aimée, Carmona, Mar, Capron, Alexander, Cardillo, Massimo, Carella, Claudia, Castillo, María Esther, Cervantes, Lilia, Chandrasekar, Akila, Chaouali, Mafaten, Chatzixiros, Efstratios, Ciccocioppo, Rachele, Cillo, Umberto, Cloherty, Jenny, Colenbie, Luc, Coll, Elisabeth, Cooper, Matthew, Correa-Rocha, Rafael, Cortesi, Paolo Angelo, Cozzi, Emanuele, Cuende, Natividad, Cuero, César, Antonio Da Silva, Juan, Daga, Domingo, Danielyan, Samvel, Danovitch, Gabriel, de Andrade, Joel, de Angelis, Vincenzo, Dedinska, Ivana, del Río, Francisco J., Delmonico, Francis L., Di Ciaccio, Paola, Doerr, Petra, Domínguez-Gil, Beatriz, Emery, Marie-Pierre, Espinel, Mauricio, Fadhil, Riadh, Foeken, Lydia, Forsberg, Anna, Forsythe, John L. R., Friend, Peter, Gadžijev, Andrej, Gallego, Daniel, Gardiner, Dale, Gatt, Sandra, Gjerek, Jernej, Gondolesi, Gabriel, Haraldsson, Börje, Hasal, Antonín, Hennerbichler, Simone, Hernández-Maraver, Dolores, Herson, Marisa, Hickey, Laura, Humar, Simona, Ilbawi, Andre, Immer, Franz, Izeta, Ander, Hawthorne, Wayne J., Jha, Vivekanand, Joyce, Ruth, Jusinskis, Janis, Kaminski, Artur, Kazancıoğlu, Rümeyza, Kim, Joe, Lentine, Krista L., Fraga, Marta López, Lundin, Kersti, Mahillo, Beatriz, Maier, Philip, Mallet, Laurent, Manas, Derek, Manyalich, Marti, Marco, Jaime, Martin, Dominique E., Martínez-Donate, María Dolores, Martjak, Marge, McGee, Andrew, McPhaden, Marcelle, Menjívar, Ana, Mey, Devi, Mihály, Sándor, Mihelčič, Petra, Miñambres, Eduardo, Mirabet, Sonia, Mojsova Mijovska, Maja, Montrasio, Lorenzo, María Moraleda, Jose, Morales, Fernando, Mueller, Thomas, Muller, Elmi, Musquera, Mireia, Nagral, Sanjay, Nathan, Naomi, Nikolac, Vanja, Niño Murcia, Alejandro, Noel, Luc, O’Sullivan, Siobhan, Oniscu, Gabriel C., Opdam, Helen, Orlando, Giuseppe, Ortega, Noelia, Padilla, Benita, Papatheodoridis, George, Pérez Bech, Eva, Pérez Blanco, Alicia, Pérez Martínez, Antonio, Perojo, Dolores, Pires Silva, Ana, Plattner, Verena, Porte, Robert, Potashnik, Anna, Potena, Luciano, Gilberto Prasca, Tomás, Premužić, Marina, Procaccio, Francesco, Rahmel, Axel, Randazzo, Enrico, Raptis, Dimitri A, Rela, Mohamed, Resanović, Vladimir, Rizzolo, Katherine, Adina Rugescu, Iona, Ruiz-Pérez, Blanca, Sainte-Marie, Isabelle, Angelica Salinas, Maria, Sánchez Ibáñez, Jacinto, Serrano, Roselyn, Shaheen, Faissal A., Shemie, Sam, Snyder, Jon, Marie Sørensen, Ragnhild, Spiro, Michael, Stock, Peter, Subotić-Popović, Andreja, Gracious, Noble, Sureda, Ana, Tassot, Johanna, ten Ham, Renske, Thomson, David, Timbalari, Tatiana, Torres, Martín, Tort, Jaume, Trias, Esteve, Trojan, Diletta, Tsimaratos, Mitchel, Tullius, Stefan G., Van Assche, Kristof, Van der Spiegel, Stefaan, Vatachki, Guenadiy, Velasco, Belén, Villatoro, Matías, Walsh, John, Wang, Haibo, and Waterman, Amy

Published
2025
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4. Building Kidney Exchange Programmes in Europe – An Overview of Exchange Practice and Activities

Author

Biró, Péter, Haase-Kromwijk, Bernadette, Andersson, Tommy, Ásgeirsson, Eyjólfur Ingi, Baltesová, Tatiana, Boletis, Ioannis, Bolotinha, Catarina, Bond, Gregor, Böhmig, Georg, Burnapp, Lisa, Cechlárová, Katarína, Di Ciaccio, Paola, Fronek, Jiri, Hadaya, Karine, Hemke, Aline, Jacquelinet, Christian, Johnson, Rachel, Kieszek, Rafal, Kuypers, Dirk, Leishman, Ruthanne, Macher, Marie-Alice, Manlove, David, Menoudakou, Georgia, Salonen, Mikko, Smeulders, Bart, Sparacino, Vito, Spieksma, Frits, de la Oliva Valentín Muñoz, María, Wilson, Nic, and vd Klundert, Joris

Published
2018
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7. Organ Donation: Perception and Will Expression in the Italian Population

Author

Cardillo Massimo, Tomaino, Silvia Caterina Maria, Procaccio, Francesco, Brena, Alessandra, Di Ciaccio, Paola, Margherita, Gentile, and Cipolletta, Sabrina

Subjects
Centro Nazionale Trapianti, attitudes, organ donation, post-mortem organ donation, focus groups, Italian population, will expression
Abstract

This study investigates the perception of organ donation and will expression in the Italian population, using focus groups in order to develop better intervention and campaign to raise awareness.

Published
2020
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8. Building Kidney Exchange Programmes in Europe—An Overview of Exchange Practice and Activities

Author

Biró, Péter, primary, Haase-Kromwijk, Bernadette, additional, Andersson, Tommy, additional, Ásgeirsson, Eyjólfur Ingi, additional, Baltesová, Tatiana, additional, Boletis, Ioannis, additional, Bolotinha, Catarina, additional, Bond, Gregor, additional, Böhmig, Georg, additional, Burnapp, Lisa, additional, Cechlárová, Katarína, additional, Di Ciaccio, Paola, additional, Fronek, Jiri, additional, Hadaya, Karine, additional, Hemke, Aline, additional, Jacquelinet, Christian, additional, Johnson, Rachel, additional, Kieszek, Rafal, additional, Kuypers, Dirk R., additional, Leishman, Ruthanne, additional, Macher, Marie-Alice, additional, Manlove, David, additional, Menoudakou, Georgia, additional, Salonen, Mikko, additional, Smeulders, Bart, additional, Sparacino, Vito, additional, Spieksma, Frits C.R., additional, Valentín, María Oliva, additional, Wilson, Nic, additional, and van der Klundert, Joris, additional

Published
2019
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9. Cross Border Organ Exchange Among EU Members States. Preliminary Results of the Foedus-EOEO it Portal

Author

Carella, Claudia, primary, Di Ciaccio, Paola, additional, Adamec, Miloš, additional, Laouabdia, Karim, additional, Huot, Olivier, additional, Martínez, Itziar, additional, Uruñuela, David, additional, Immer, Franz, additional, Beyeler, Franziska, additional, Czerwiński, Jarosław, additional, Danek, Teresa, additional, Szemis, Łukasz, additional, Kuba, Daniel, additional, Kratka, Magdalena, additional, Roberts, Mark, additional, Johnson, Sally, additional, Būziuvienė, Audronė, additional, and Fryda, Premysl, additional

Published
2017
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10. The effect of differing kidney disease treatment modalities and organ donation and transplantation practices on health expenditure and patient outcomes

Author

Jager, Kitty J, primary, Stel, Vianda S, additional, Branger, Peter, additional, Guijt, Marja, additional, Busic, Mirela, additional, Dragović, Marijana, additional, Diekmann, Fritz, additional, Manyalich, Martí, additional, Di Ciaccio, Paola, additional, Nanni Costa, Alessandro, additional, Collett, Dave, additional, Mumford, Lisa, additional, Haase, Bernadette, additional, Hemke, Aline, additional, Deme, Orsolya, additional, Mihály, Sándor, additional, Murphy, Mark, additional, Couchoud, Cécile, additional, Massy, Ziad, additional, Lingemann, Marie, additional, and Rahmel, Axel, additional

Published
2017
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12. IItaly’s successful restructuring programme

Author

Venettoni Sante, Nanni Costa Alessandro, Di Ciaccio Paola, Ghirardini Angelo, Mattucci Dino, Santangelo Giorgia, Buscaroli Andrea, Peter Morris, and Venettoni Sante, Nanni Costa Alessandro, Di Ciaccio Paola, Ghirardini Angelo, Mattucci Dino, Santangelo Giorgia, Buscaroli Andrea

Subjects
surgical procedures, operative, transplants, bioethics
Abstract

Organ and tissue transplants are the result of a process that begins with identifying a potential donor and ends with the transplant operation itself.

Published
2003

13. Organ donor screening for carbapenem‐resistant gram‐negative bacteria in Italian intensive care units: the DRIn study

Author

Procaccio, Francesco, Masiero, Lucia, Vespasiano, Francesca, Grossi, Paolo A., Gagliotti, Carlo, Pantosti, Annalisa, Caprio, Mario, Lombardini, Letizia, Nanni Costa, Alessandro, Maccarone, Daniela, Giacon, Bruno, Saracino, Angelo, Mancini, Pellegrino, Giannattasio, Paolo, Sangiorgi, Gabriela, Licari, Maurizia, Valeri, Maurizio, Munoz Lopez, Montserrat, Moschini, Massimo, Giacometti, Raffaella, Panebianco, Annarita, Littera, Roberto, Butera, Angelita, Bonizzoli, Manuela, Pilati, Laura, Dovas, Atanassios, Lazzarini, Fabio, Coluccio, Elena, Vesconi, Sergio, Ghirardini, Angelo, Puoti, Francesca, Ricci, Andrea, and Di Ciaccio, Paola

Abstract

The 759 cases of brain death declaration (BDD [Italian law, 6 hours of observation time]) that occurred in 190 Italian intensive care units (ICUs) between May and September 2012 were studied to quantify carbapenem‐resistant gram‐negative bacteria (CR‐GN) isolated in organ donors, to evaluate adherence to national screening guidelines, and to identify risk factors for CR‐GNisolation. Mandatory blood, bronchoalveolar lavage, and urine cultures were performed on the BDDday in 99% of used donors. Because results were rarely made available before transplant, >20% of transplants were performed before obtaining any microbiological information, and organs from 15 of 22 CR‐GNcases were used. Two (lung–liver) of the 37 recipients died, likely because of donor‐derived early CR‐GNsepsis. ICUstay >3 days (odds ratio [OR] = 7.49, P= .004), fever (OR= 3.11, P= .04), age <60 years (OR= 2.80, P= .06), and positive ICUepidemiology (OR= 8.77, P= .07) were associated with CR‐GNisolation. An association between single ICUand risk of CR‐GNwas observed, as a result of differences across ICUs (ICC= 29%; 95% confidence interval [CI] 6.5%‐72%) probably related to inadequate practices of infection control. Continuous education aimed at implementing priority actions, including stewardship programs for a rational use of antimicrobials, is a priority in healthcare systems and transplant networks. Improved awareness among ICUpersonnel regarding the importance of early CR‐GNdetection and timely alert systems might facilitate decisions regarding organ suitability and eventually save recipient lives. In this national study, the authors evaluate the risk factors for carbapenem‐resistant, gram‐negative bacteria isolation in brain dead organ donors and possibly related recipient deaths, suggesting that tailored surveillance cultures, timely information, and alert systems based on critical care personnel education and transplant network organization might facilitate and improve decisions regarding organ suitability.

Published
2020
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14. Vigilance: Lessons learned from the tissue and cell experiance in the European Union. Part I: Reporting and communication

Author

1. Fehily, Deirdre, Uhrynowska-Tyszkiewicz, Izabela, Creusvaux, Hervè, Pariente-Khayat, Ann, Kaminski, Artur, Olender, Ewa, Manjaji, Elvira, Swann, Imogen, Sornarajah, Renuka, Costello, Patrick, Harkin, Donna, Masterson, Sinead, Alvarez, Marina, Cantarero, Gregorio Garrido, Smith, Mike, Roels, Leo, Teskrat, Fewzi, O’Toole, Chris, Funk, Markus, Golubić Ćepulić, Branka, Nikolac, Vanja, Mareri, Maura, Porta, Eliana, Ghirardini, Angelo, di Ciaccio, Paola, Noel, Luc, and Nanni Costa, Alessandro

Subjects
Vigilance, tissues, cells, serious adverse events
Abstract

SOHO V&S (Vigilance and Surveillance of Substances of Human Origin) was a project co-funded by the European Union Public Health Programme. The project ran from March 2010 to February 2013. Its scope included tissues and cells for transplantation and gametes and embryos for assisted reproduction. The broad aim of the project was to support European Union Member States in the establishment of effective vigilance and surveillance (V&S) systems for tissues and cells used for human applications, including transplantation and assisted reproduction, ensuring the adoption of a common approach that would allow sharing of data and didactic information for the improvement of safety and quality. To achieve this broad objective, a number of key activities were carried out, including the development of guidance to EU Competent Authorities on the investigation and management of severe adverse reactions and events associated with tissues and cells for transplantation and for assisted reproduction. Equivalent guidance was developed for professionals in European Union hospitals and clinics who apply human tissues and cells to their patients. The latter guidance addressed the roles and responsibilities of clinical users in relation to supporting traceability and vigilance of tissues and cells for transplantation and assisted reproduction. This article, and its sister article (due to in March 2014), describe the key issues that arose and the conclusions reached in the development of these two guidance documents. This article describes the key points of guidance developed on reporting and communication of serious adverse events and reactions.

Published
2013

15. Vigilance: lessons learned from the tissue and cell experience in the european union. Part 1: reporting and communication

Author

Fehily, Deirdre, Uhrynowska-Tyszkiewicz, Izabela, Creusvaux, Hervè, Pariente-Khayat, Artur, Kaminski, Ann, Olender, Ewa, Manjaji, Elvira, Swann, Imogen, Sornarajah, Renuka, Costello, Patrick, Harkin, Donna, Sinead Masterson5 , Marina Alvarez6 , Gregorio Garrido Cantarero6 , Mike Smith7 , Leo Roels7 , Teskrat, Fewzi, O’Toole, Chris, Funk, Markus, Golubić Ćepulić, Branka, Nikolac, Vanja, Mareri, Maura, Porta, Eliana, Ghirardini, Angelo, di Ciaccio, Paola, Noel, Luc, and Nanni Costa, Alessandro

Subjects
Vigilance, tissues, cells, serious adverse events, serious adverse reactions, reporting, detection, communication
Abstract

SOHO V&S (Vigilance and Surveillance of Substances of Human Origin) was a project co-funded by the European Union Public Health Programme. The project ran from March 2010 to February 2013. Its scope included tissues and cells for transplantation and gametes and embryos for assisted reproduction. The broad aim of the project was to support European Union Member States in the establishment of effective vigilance and surveillance (V&S) systems for tissues and cells used for human applications, including transplantation and assisted reproduction, ensuring the adoption of a common approach that would allow sharing of data and didactic information for the improvement of safety and quality. To achieve this broad objective, a number of key activities were carried out, including the development of guidance to EU Competent Authorities on the investigation and management of severe adverse reactions and events associated with tissues and cells for transplantation and for assisted reproduction. Equivalent guidance was developed for professionals in European Union hospitals and clinics who apply human tissues and cells to their patients. The latter guidance addressed the roles and responsibilities of clinical users in relation to supporting traceability and vigilance of tissues and cells for transplantation and assisted reproduction. This article, and its sister article (due to in March 2014), describe the key issues that arose and the conclusions reached in the development of these two guidance documents. This article describes the key points of guidance developed on reporting and communication of serious adverse events and reactions

Published
2013

16. The effect of differing kidney disease treatment modalities and organ donation and transplantation practices on health expenditure and patient outcomes.

Author

Jager, Kitty J., Stel, Vianda S., Branger, Peter, Guijt, Marja, Busic, Mirela, Dragović, Marijana, Diekmann, Fritz, Manyalich, Martí, Di Ciaccio, Paola, Costa, Alessandro Nanni, Collett, Dave, Mumford, Lisa, Haase, Bernadette, Hemke, Aline, Deme, Orsolya, Mihály, Sándor, Murphy, Mark, Couchoud, Cécile, Massy, Ziad, and Lingemann, Marie

Subjects
KIDNEY disease treatments, KIDNEY transplantation, ORGAN donation, MEDICAL care costs, KIDNEY function tests
Abstract

The Effect of Differing Kidney Disease Treatment Modalities and Organ Donation and Transplantation Practices on Health Expenditure and Patient Outcomes (EDITH) aims to obtain information on long-term kidney transplant outcomes, long-term health outcomes of living kidney donors and detailed outcomes and costs related to the different treatment modalities of end-stage kidney disease. Nine partners from seven European Union countries will participate in this project. [ABSTRACT FROM AUTHOR]

Published
2018
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18. Infections in liver and lung transplant recipients. A national prospective cohort

Author

Gagliotti, Carlo, Morsillo, Filomena, Moro, Maria Luisa, Masiero, Lucia, Procaccio, Francesco, Vespasiano, Francesca, Pantosti, Annalisa, Monaco, Monica, Errico, Giulia, Ricci, Andrea, Grossi, Paolo, Nanni Costa, Alessandro, Adorno, D., Ambretti, S., Amoroso, A., Arghittu, M., Berloco, P., Bertani, A., Bonizzoli, M., Cambieri, P., Canzonieri, M., Caprio, M., Carrara, E., Carrinola, R., Cibelli, E., Cillo, U., Colledan, M., Colombo, R., Coluccio, E., Conaldi, P. G., Cusi, M., D’Armini, A. M., da Riva, A., D’Auria, B., de Carlis, L., de Cillia, C., de Gasperi, A., Di Caro, A., Di Ciaccio, P., Dondossola, D., Farina, C., Feltrin, G., Finarelli, A. C., Fossati, L., Gaibani, P., Garcia Fernandez, A., Gesu, G., Giacometti, R., Gona, F., Gridelli, B., Henrici de Angelis, L., Landini, M. P., Maldarelli, F., Mancini, C., Marone, P., Mularoni, A., Paglialunga, G., Paladini, P., Palù, G., Parisi, S., Peris, A., Pinna, A. D., Platto, M., Pugliese, F., Puoti, F., Rago, C., Ravini, M., Rea, F., Rinaldi, M., Rossi, G., Rossi, L., Rossi, M., Salizzoni, M., Sangiorgi, G., Santambrogio, L., Spada, M., Sparacino, V., Stella, F., Torelli, R., Torresani, E., Tosi, D., Vailati, F., Valeri, M., Venuta, F., Vesconi, S., Viale, P., Vismara, C., Gagliotti, C, Morsillo, F, Moro, M, Masiero, L, Procaccio, F, Vespasiano, F, Pantosti, A, Monaco, M, Errico, G, Ricci, A, Grossi, P, Nanni Costa, A, Adorno, D, Ambretti, S, Amoroso, A, Arghittu, M, Berloco, P, Bertani, A, Bonizzoli, M, Cambieri, P, Canzonieri, M, Caprio, M, Carrara, E, Carrinola, R, Cibelli, E, Cillo, U, Colledan, M, Colombo, R, Coluccio, E, Conaldi, P, Cusi, M, D’Armini, A, da Riva, A, D’Auria, B, de Carlis, L, de Cillia, C, de Gasperi, A, Di Caro, A, Di Ciaccio, P, Dondossola, D, Farina, C, Feltrin, G, Finarelli, A, Fossati, L, Gaibani, P, Garcia Fernandez, A, Gesu, G, Giacometti, R, Gona, F, Gridelli, B, Henrici de Angelis, L, Landini, M, Maldarelli, F, Mancini, C, Marone, P, Mularoni, A, Paglialunga, G, Paladini, P, Palù, G, Parisi, S, Peris, A, Pinna, A, Platto, M, Pugliese, F, Puoti, F, Rago, C, Ravini, M, Rea, F, Rinaldi, M, Rossi, G, Rossi, L, Rossi, M, Salizzoni, M, Sangiorgi, G, Santambrogio, L, Spada, M, Sparacino, V, Stella, F, Torelli, R, Torresani, E, Tosi, D, Vailati, F, Valeri, M, Venuta, F, Vesconi, S, Viale, P, Vismara, C, Gagliotti, Carlo, Morsillo, Filomena, Moro, Maria Luisa, Masiero, Lucia, Procaccio, Francesco, Vespasiano, Francesca, Pantosti, Annalisa, Monaco, Monica, Errico, Giulia, Ricci, Andrea, Grossi, Paolo, Costa, Alessandro Nanni, Adorno, Domenico, Ambretti, Simone, Amoroso, Antonio, Arghittu, Milena, Berloco, Pasquale, Bertani, Alessandro, Bonizzoli, Manuela, Cambieri, Patrizia, Canzonieri, Marco, Caprio, Mario, Carrara, Elena, Carrinola, Rosaria, Cibelli, Eva, Cillo, Umberto, Colledan, Michele, Colombo, Rosaria, Coluccio, Elena, Conaldi, Pier Giulio, Cusi, Mariagrazia, D’Armini, Andrea Maria, Da Riva, Adelaide, D'Auria, Bianca, De Carlis, Luciano, De Cillia, Carlo, De Gasperi, Andrea, Di Caro, Antonino, Di Ciaccio, Paola, Dondossola, Daniele, Farina, Claudio, Feltrin, Giuseppe, Finarelli, Alba Carola, Fossati, Lucina, Gaibani, Paolo, Fernandez, Aurora Garcia, Gesu, Giovanni, Giacometti, Raffaella, Gona, Floriana, Gridelli, Bruno, De Angelis, Lucia Henrici, Landini, Maria Paola, Maldarelli, Federica, Mancini, Carlo, Marone, Piero, Mularoni, Alessandra, Paglialunga, Giulia, Paladini, Piero, Palù, Giorgio, Parisi, Saverio, Peris, Adriano, Pinna, Antonio Daniele, Platto, Marco, Pugliese, Francesco, Puoti, Francesca, Rago, Claudio, Ravini, Mario, Rea, Federico, Rinaldi, Mauro, Rossi, Giorgio, Rossi, Lucia, Rossi, Massimo, Salizzoni, Mauro, Sangiorgi, Gabriela, Santambrogio, Luigi, Spada, Marco, Sparacino, Vito, Stella, Franco, Torelli, Rosanna, Torresani, Erminio, Tosi, Davide, Vailati, Francesca, Valeri, Maurizio, Venuta, Federico, Vesconi, Sergio, Viale, Pierluigi, and Vismara, Chiara

Subjects
Microbiology (medical), Infectious Diseases, Male, 0301 basic medicine, medicine.medical_treatment, Drug Resistance, Transplant Recipient, 030230 surgery, Liver transplantation, Postoperative Complications, 0302 clinical medicine, Drug Resistance, Multiple, Bacterial, Medicine, Cumulative incidence, Prospective Studies, Prospective cohort study, Incidence, Incidence (epidemiology), Mortality rate, Bacterial, Bacterial Infections, General Medicine, Middle Aged, lung transplant, Anti-Bacterial Agents, infectious, Italy, Female, Multiple, Adult, Bacteria, Humans, Transplant Recipients, Liver Transplantation, Lung Transplantation, Human, medicine.medical_specialty, 030106 microbiology, Bacterial Infection, Infectious Diseases, transplantation, 03 medical and health sciences, Internal medicine, Anti-Bacterial Agent, Lung transplantation, business.industry, lung transplant, liver transplant, infectious, Transplantation, Prospective Studie, liver transplant, Etiology, Postoperative Complication, business, transplantation
Abstract

Infections are a major complication of solid organ transplants (SOTs). This study aimed to describe recipients’ characteristics, and the frequency and etiology of infections and transplant outcome in liver and lung SOTs, and to investigate exposures associated to infection and death in liver transplant recipients. The study population included recipients of SOTs performed in Italy during a 1-year period in ten Italian lung transplant units and eight liver transplant units. Data on comorbidities, infections, retransplantation, and death were prospectively collected using a web-based system, with a 6-month follow-up. The cumulative incidence of infection was 31.7% and 47.8% in liver and lung transplants, respectively, with most infections occurring within the first month after transplantation. Gram-negatives, which were primarily multidrug-resistant, were the most frequent cause of infection. Death rates were 0.42 per 1000 recipient-days in liver transplants and 1.41 per 1000 recipient-days in lung transplants. Infection after SOT in adult liver recipients is associated to an increased risk of death (OR = 13.25; p-value < 0.001). Given the frequency of infection caused by multidrug-resistant microorganisms in SOT recipients in Italy and the heavy impact of infections on the transplant outcome, the reinforcement of surveillance and control activities to prevent the transmission of multidrug-resistant microorganisms in SOT recipients represents a priority. The implementation of the study protocol in liver and lung transplant units and the sharing of results have increased the awareness about the threat due to antimicrobial resistance in the country.

Published
2018

19. Kidney transplantation and withdrawal rates among wait-listed first-generation immigrants in Italy.

Author

Grossi AA, Puoti F, Fiaschetti P, Di Ciaccio P, Maggiore U, and Cardillo M

Subjects
Adult, Humans, Living Donors, Retrospective Studies, Waiting Lists, Emigrants and Immigrants, Kidney Transplantation adverse effects
Abstract

Background: Multiple barriers diminish access to kidney transplantation (KT) in immigrant compared to non-immigrant populations. It is unknown whether immigration status reduces the likelihood of KT after wait-listing despite universal healthcare coverage with uniform access to transplantation., Methods: We retrospectively collected data of all adult waiting list (WL) registrants in Italy (2010-20) followed for 5 years until death, KT in a foreign center, deceased-donor kidney transplant (DDKT), living-donor kidney transplant (LDKT) or permanent withdrawal from the WL. We calculated adjusted relative probability of DDKT, LDKT and permanent WL withdrawal in different immigrant categories using competing-risks multiple regression models., Results: Patients were European Union (EU)-born (n = 21 624), Eastern European-born (n = 606) and non-European-born (n = 1944). After controlling for age, sex, blood type, dialysis vintage, case-mix and sensitization status, non-European-born patients had lower LDKT rates compared to other immigrant categories: LDKT adjusted relative probability of non-European-born vs. Eastern European-born 0.51 (95% CI: 0.33-0.79; P = 0.002); of non-European-born vs. EU-Born: 0.65 (95% CI: 0.47-0.82; P = 0.001). Immigration status did not affect the rate of DDKT or permanent WL withdrawal., Conclusions: Among EU WL registrants, non-European immigration background is associated with reduced likelihood of LDKT but similar likelihood of DDKT and permanent WL withdrawal. Wherever not available, new national policies should enable coverage of travel and medical fees for living-donor surgery and follow-up for non-resident donors to improve uptake of LDKT in immigrant patients, and provide KT education that is culturally competent, individually tailored and easily understandable for patients and their potential living donors., (© The Author(s) 2022. Published by Oxford University Press on behalf of the European Public Health Association.)

Published
2022
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