576 results on '"Di Donato S."'
Search Results
2. POS0404 MRI DAVIX INDEX SHOWS BIOLOGICAL FACE VALIDITY: CYTOFLUORIMETRY ANALYSIS TO UNCOVER THE RELATIONSHIP BETWEEN VASCULAR DAMAGE AND ENDOTHELIAL CELL POPULATIONS IN SYSTEMIC SCLEROSIS PATIENTS AND UNDERPIN A CELLULAR PHENOTYPING OF PATIENTS
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DI Donato, S., primary, Ross, R., additional, El-Sherbiny, Y., additional, Wasson, C. W., additional, Schmitz, J., additional, Visvanathan, S., additional, and Del Galdo, F., additional
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- 2024
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3. AB1208 CLINICALLY RELEVANT DIFFERENCES BETWEEN PRIMARY AND SECONDARY RAYNAUD’S PHENOMENON SECONDARY TO CONNECTIVE TISSUE DISEASES: RESULTS FROM A LARGE INTERNATIONAL SURVEY
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Di Donato, S., primary, Huang, S., additional, Pauling, J., additional, Sabbagh, M., additional, Khanna, D., additional, and Hughes, M., additional
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- 2024
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4. AB1150 TYPE I INTERFERON ACTIVATION OF MONOCYTES IN SYSTEMIC SCLEROSIS IS CGAS-STING DEPENDENT AND CAN BE DIRECTLY INDUCED BY DERMAL FIBROBALSTS: A PROMISING THERAPEUTIC TARGET
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Di Donato, S., primary, Ross, R., additional, Wasson, C. W., additional, Schmitz, J., additional, Li, J., additional, Visvanathan, S., additional, and Del Galdo, F., additional
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- 2024
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5. OP0314 INTERFERON SCORE AS A NOVEL TRIAL ENRICHMENT TOOL TO PREDICT CLINICAL OUTCOMES IN PATIENTS WITH LIMITED CUTANEOUS SYSTEMIC SCLEROSIS
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DI Donato, S., primary, Ross, R., additional, Karanth, R., additional, Kakkar, V., additional, De Lorenzis, E., additional, Abignano, G., additional, Clark, K., additional, Denton, C. P., additional, and Del Galdo, F., additional
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- 2024
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6. Prognostic and predictive role of neutrophil/lymphocytes ratio in metastatic colorectal cancer: a retrospective analysis of the TRIBE study by GONO
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Dell’Aquila, E., Cremolini, C., Zeppola, T., Lonardi, S., Bergamo, F., Masi, G., Stellato, M., Marmorino, F., Schirripa, M., Urbano, F., Ronzoni, M., Tomasello, G., Zaniboni, A., Racca, P., Buonadonna, A., Allegrini, G., Fea, E., Di Donato, S., Chiara, S., Tonini, G., Tomcikova, D., Boni, L., Falcone, A., and Santini, D.
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- 2018
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7. Pattern of recurrence and overall survival in esophagogastric cancer after perioperative FLOT and clinical outcomes in MSI-H population: the PROSECCO Study
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Nappo F., Fornaro L., Pompella L., Catanese S., Lavacchi D., Spallanzani A., Cappetta A., Puzzoni M., Murgioni S., Barsotti G., Tirino G., Pellino A., Vivaldi C., Strippoli A., Aprile G., Di Donato S., Mazza E., Prisciandaro M., Antonuzzo L., Zagonel V., Cascinu S., De Vita F., Lonardi S., Nappo, F., Fornaro, L., Pompella, L., Catanese, S., Lavacchi, D., Spallanzani, A., Cappetta, A., Puzzoni, M., Murgioni, S., Barsotti, G., Tirino, G., Pellino, A., Vivaldi, C., Strippoli, A., Aprile, G., Di Donato, S., Mazza, E., Prisciandaro, M., Antonuzzo, L., Zagonel, V., Cascinu, S., De Vita, F., and Lonardi, S.
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Cancer Research ,Gastro-esophageal junction adenocarcinoma ,Perioperative chemotherapy ,Oncology ,Microsatellite instability statu ,FLOT ,General Medicine ,Gastric cancer - Abstract
Background FLOT regimen is the standard perioperative treatment in Western countries for patients with locally advanced gastric (GC) or gastroesophageal junction cancer (GEJC). High microsatellite instability (MSI-H) and Mismatch Repair deficient (dMMR) demonstrated a favorable prognostic role and a concomitant negative predictive impact on the benefit of perioperative 5-fluorouracil-based doublets; however, its role in pts receiving FLOT chemotherapy is still unclear. Methods This is a retrospective, multicenter observational study of 265 pts with GC/GEJC treated with perioperative FLOT regimen in 11 Italian oncology centers between January 2017 to December 2021 and analyzed for microsatellite status. Results The MSI-H phenotype was found in 27 (10.2%) of 265 analyzed tumors. Compared to microsatellite stable (MSS) and Mismatch Repair proficient (pMMR) cases, MSI-H/dMMR were more frequently female (48.1% vs. 27.3%, p = 0.0424), elderly pts (age > 70 years, 44.4% vs. 13.4%, p = 0.0003), Laurens’s intestinal type (62.5% vs. 36.1%, p = 0.02) and pts with a primary location tumor in the antrum (37 vs. 14.3%, p = 0.0004). A statistically significant difference in the rate of pathologically negative lymph node emerged (63% vs 30.7%, p = 0.0018). Compared to the MSS/pMMR tumor population, the MSI-H/dMMR subgroup had a better DFS (median not reached [NR] vs. 19.5 [15.59–23.59] mos, p = 0.031) and OS (median NR vs. 34.84 [26.68–47.60] mos, p = 0.0316). Conclusions These real-world data confirm that FLOT treatment is effective in daily clinical practice for locally advanced GC/GEJC, also in the MSI-H/dMMR subgroup. It also showed a higher rate of nodal status downstaging and a better outcome of MSI-H/dMMR pts in comparison to MSS/pMMR.
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- 2023
8. POS1336 MRI DIGITAL ARTERY VOLUME INDEX (DAVIX©) AS QUANTITATIVE, CONTINUOUS IMAGING OUTCOME MEASURE OF VASCULAR DISEASE IN SYSTEMIC SCLEROSIS
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Hughes, M., primary, Di Donato, S., additional, Gjeloshi, K., additional, Abignano, G., additional, Danzo, F., additional, Lettieri, G., additional, De Lorenzis, E., additional, Bertham, D., additional, O’connor, P., additional, Kubassova, O., additional, Dehmeshki, J., additional, and Del Galdo, F., additional
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- 2023
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9. POS1257 CCL24 SERUM CONCENTRATION PREDICTS BOTH VASCULAR AND FIBROTIC COMPLICATIONS IN SYSTEMIC SCLEROSIS
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De Lorenzis, E., primary, Mor, A., additional, Ross, R., additional, DI Donato, S., additional, Aricha, R., additional, Levi, I., additional, Vaknin, I., additional, and Del Galdo, F., additional
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- 2023
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10. AB0881 CLINICAL TRAJECTORIES OF MULTIFACTORIAL HAND FUNCTION DETERIORATION IN SYSTEMIC SCLEROSIS
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De Lorenzis, E., primary, Kakkar, V., additional, Di Donato, S., additional, Wilson, M., additional, Barnes, T., additional, Saleem, B., additional, Herrick, A., additional, Nisar, M., additional, Morley, C., additional, Douglas, K., additional, Denton, C. P., additional, Derret-Smith, E., additional, Heliwell, P., additional, Green, L., additional, Alcacer-Pitarch, B., additional, and Del Galdo, F., additional
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- 2023
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11. Investigation of the skin contamination predictability by means of QForm UK extrusion code
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Kniazkin, I., Pelaccia, R., Negozio, M., Di Donato, S., Donati, L., Reggiani, B., Biba, N., Rezvykh, R., and Kulakov, I.
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Skin Contamination ,Back-End Defect ,FEM ,QForm Extrusion ,ALE Approach - Abstract
The paper presents an innovative approach implemented in QForm UK Extrusion FEM software to analyse one of the core defects encountered in profile extrusion known as billet skin defect. The validation of the algorithm has been performed based on a number of experimental case studies taken from the literature [1,2]. Additionally, the sensitivity of the accuracy of the results to the variation in initial parameters has been analysed for both types of profile shapes: solid and hollow. Based on this, practical recommendations have been formalised for the successful industrial use of the presented algorithm.
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- 2023
12. Experimental analysis and modeling of the recrystallization behaviour of a AA6060 extruded profile
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Negozio, M., Donati, L., Pelaccia, R., Reggiani, B., and Di Donato, S.
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6XXX ,FEM ,Extrusion ,Aluminum Alloy ,Microstructure ,Recrystallization - Abstract
The microstructure of Al-Mg-Si alloys is gaining nowadays an increasing industrial interest because it influences the strength, crash, corrosion and esthetic properties of the extruded profiles. In order to investigate and predict the recrystallization behaviour in the extrusion of 6XXX aluminum alloys, experimental and numerical activities are still needed. In this work, the extrusion of an industrial-scale AA6060 aluminum alloy hollow profile was carried out. An innovative recrystallization model was developed and optimized by comparing the microstructural data experimentally acquired with the outputs of the simulation performed using the Finite Element commercial code Qform Extrusion. A good correlation between numerical prediction and experimental data was found, thus proving the reliability of the proposed AA6060 recrystallization model.
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- 2023
13. Investigation on the topological optimization of cooling channels for extrusion dies
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Pelaccia, R., Reggiani, B., Negozio, M., Di Donato, S., and Donati, L.
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Cooling Channels ,Extrusion ,Topological Optimization ,Liquid Nitrogen ,Dies - Abstract
During the extrusion process, high temperatures are generated, due to friction and deformation works, potentially leading to profile and die defects. Among the suggested solutions aimed at controlling the thermal field of the process, the most accredited one involves the manufacturing of cooling channels at the mating face between the die and a third plate. Despite the proven efficiency of well-designed channels, the main drawback lies in the managing of the many variables involved that strongly affect the cooling efficiency and balancing. In this frame, aim of the work is to investigate the applicability of the topological optimization tool, proposed by COMSOL Multiphysics software, for the design of cooling channels in extrusion dies. To validate the tool, an industrial case study has been selected and results compared between not optimized and optimized cooling solutions.
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- 2023
14. Autologous micro-fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis: an update at 3 year follow-up
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Russo, A., Screpis, D., Di Donato, S. L., Bonetti, S., Piovan, G., and Zorzi, C.
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- 2018
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15. Are all people with diabetes and cardiovascular risk factors or microvascular complications at very high risk? Findings from the Risk and Prevention Study
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Marzona, Irene, Avanzini, Fausto, Lucisano, Giuseppe, Tettamanti, Mauro, Baviera, Marta, Nicolucci, Antonio, Roncaglioni, Maria Carla, Tombesi, M., Tognoni, G., Massa, E., Marrocco, W., Micalella, M., Caimi, V., Longoni, P., Avanzini, F., Franzosi, M. G., Roncaglioni, M. C., Marzona, I., Baviera, M., Monesi, L., Pangrazzi, I., Barlera, S., Milani, V., Nicolis, E., Casola, C., Clerici, F., Palumbo, A., Sgaroni, G., Marchioli, R., Silletta, M. G., Pioggiarella, R., Scarano, M., Marfisi, R. M., Flamminio, A., Macino, L., Ferri, B., Pera, C., Polidoro, A., Abbatino, D., Acquati, M., Addorisio, G., Adinolfi, D., Adreani, L., Agistri, M. R., Agneta, A., Agnolio, M. L., Agostini, N., Agostino, G., Airò, A., Alaimo, N., Albano, M., Albano, N., Alecci, G., Alemanno, S., Alexanian, A., Alfarano, M., Alfè, L., Alonzo, N., Alvino, S., Ancora, A., Andiloro, S., Andreatta, E., Angeli, S., Angiari, F., Angilletti, V., Annicchiarico, C., Anzivino, M., Aprea, R., Aprile, A., Aprile, E., Aprile, I., Aprile, L., Armellani, V., Arnetoli, M., Aronica, A., Autiero, V., Bacca, G., Baccalaro, A. M., Bacci, M., Baglio, G., Bagnani, M., Baiano, A., Baldari, A., Ballarini, L., Banchi, G., Bandera, R., Bandini, F., Baratella, M., Barbieri, A., Barbieri Vita, A., Bardi, M., Barlocchi, M., Baron, P., Bartoli, M., Basile, A., Basile, F., Basile, S., Battaggia, A., Battaglia, A., Baù, A., Beconcini, G., Beggio, R., Belfiore, P. A., Belicchi, M., Bellamoli, S., Bellini, C., Bellomo, M., Benetollo, C., Benetti, R., Beretta, E., Bertalero, P., Bertaso, F. G., Bertolani, U., Bettelli, G., Biagiotti, G., Bianchi, S., Bianco, G., Biccari, F., Bigioli, F., Bindi, M., Bisanti, G., Bitetti, E. M., Blasetti, M. P., Blesi, F., Boato, V., Boga, S., Boidi, E., Boldrin, G., Bollati, A., Bolzan, L., Bolzonella, S., Bonardi, P., Bonato, G. B., Bonci, M., Bonfitto, G., Bonincontro, E., Boninsegna, F., Bonissone, D., Bono, L., Bonollo, E., Borghi, M., Borioli, N., Borsatto, M., Bosco, T., Bosisio Pioltelli, M., Botarelli, C., Botassis, S., Bottini, F., Bottos, C., Bova, G., Bova, V., Bozzani, A., Bozzetto, R. M., Braga, V. T., Braglia, M., Bramati, E., Brazzoli, C., Breglia, G., Brescia, A., Briganti, D., Brigato, G., Brocchi, A., Brosio, F. A., Bruni, E., Buscaglia, E., Bussini, M. D., Bussotti, A., Buzzaccarini, F., Buzzatti, A., Caccamo, G., Cacciavillani, C., Caggiano, G., Caimi, V., Calciano, F. P., Calderisi, M., Calienno, S., Caltagirone, P., Calzolari, I., Cammisa, M., Campanaro, M., Campanella, G. B., Campese, F., Canali, G., Candiani, D. E. L., Canepa, R., Canini, D., Canino, A., Cantoro, E. A., Capilupi, V., Capotosto, P., Cappelli, B., Capraro, G., Carafa, F. A., Carano, Q., Carcaterra, V., Carriero, D., Carrozzo, G., Cartanese, M., Casalena, M., Casarola, M., Caso, C., Casotto, M., Castaldi, F., Castegnaro, R., Castellani, G., Castri, S., Catalano, E., Catinello, N., Caturano, G., Cavallaro, R., Cavallo, A. M., Cavallo, G., Cavion, M. T., Cavirani, G., Cazzaniga, F., Cazzetta, D., Cecconi, V., Cefalo, A., Celebrano, M., Celora, A., Centonze, P., Cerati, D., Cesaretti, D., Checchia, G., Checchin, A., Cherubini, M., Chianese, L., Chiappa, A., Chiappa, M. V., Chiariello, G., Chiavini, G., Chicco, M., Chiumeo, F., Ciacciarelli, A., Ciaci, D., Ciancaglini, R., Cicale, C., Cicale, S., Cipolla, A., Ciruolo, A., Citeri, A. L., Citterio, G., Clerici, M., Coazzoli, E., Collecchia, G., Colletta, F., Colombo, I., Colorio, P., Coluccia, S., Comerio, M., Comoretto, P., Compagni, M., Conte, O., Contri, S., Contrisciani, A., Coppetti, T., Corasaniti, F., Corradi, M. T., Corsano, A., Corsini, A., Corti, N., Costantini, G., Costantino, A., Cotroneo, S., Cozzi, D., Cravello, M. G., Cristiano, E., Cucchi, R., Cusmai, L., D’Errico, G. B., D’Agostino, P., Dal Bianco, L., Dal Mutto, U., Dal Pozzo, G., Dallapiccola, P., Dallatorre, G., Dalle Molle, G., Dalloni, E., D’Aloiso, A., D’Amicis, G., Danese, R., Danieli, D., Danisi, G., D’Anna, M. A., Danti, G., D’Ascanio, S., Davidde, G., De Angeli, D., De Bastiani, R., De Battisti, A., De Bellis, A., De Berardinis, G., De Carlo, F., De Giorgi, D., De Gobbi, R., De Lorenzis, E., De Luca, P., De Martini, G., De Marzi, M., De Matteis, D., De Padova, S., De Polo, P., De Sabato, N., De Stefano, T., De Vita, M. T., De Vito, U., De Zolt, V., Debernardi, F., Del Carlo, A., Del Re, G., Del Zotti, F., D’Elia, R., Della Giovanna, P., Dell’Acqua, L., Dell’Orco, R. L., Demaria, G., Di Benedetto, M. G., Di Chiara, G., Di Corcia, V., Di Domizio, O., Di Donato, P., Di Donato, S., Di Fermo, G., Di Franco, M., Di Giovannantonio, G., Di Lascio, G., Di Lecce, G., Di Lorenzo, N., Di Maro, T., Di Mattia, Q., Di Michele, E., Di Modica, R. S., Di Murro, D., Di Noi, M. C., Di Paoli, V., Di Santi, M., Di Sanzo, A., Di Turi, C., Diazzi, A., Dileo, I., D’Ingianna, A. P., Dolci, A., Donà, G., Donato, C., Donato, P., Donini, A., Donna, M. E., Donvito, T. V., Esposito, L., Esposito, N., Evangelista, M., Faita, G., Falco, M., Falcone, D. A., Falorni, F., Fanciullacci, A., Fanton, L., Fasolo, L., Fassina, R., Fassone, A., Fatarella, P., Fedele, F., Fera, I., Fera, L., Ferioli, S., Ferlini, M. G., Ferlino, R., Ferrante, G., Ferrara, F. N., Ferrarese, M. F., Ferrari, G., Ferrari, O., Ferreri, A., Ferroni, M., Fezzi, G., Figaroli, C., Fina, M. G., Fioretta, A., Fiorucci, C., Firrincieli, R., Fischetti, M., Fischietti, G., Fiume, D. C., Flecchia, G., Forastiere, G., Fossati, B., Franceschi, P. L., Franchi, L., Franzoso, F., Frapporti, G., Frasca, G., Frisotti, A., Fumagalli, G., Fusco, D., Gabriele, P., Gabrieli, A., Gagliano, D., Galimberti, G., Galli, A., Gallicchio, N., Gallio, F., Gallipoli, T., Gallo, P., Galopin, T., Gambarelli, L., Garbin, A., Garozzo, G. M., Gasparri, R., Gastaldo, M., Gatti, E., Gazzaniga, P., Gennachi, N., Gentile, R. V., Germani, P., Gesualdi, F., Gherardi, E., Ghezzi, C., Ghidini, M. G., Ghionda, F., Giacci, L., Gialdini, D., Giampaolo, C., Giancane, R., Giannanti, A., Giannese, S., Giannini, L., Giaretta, M., Giaretta, R., Giavardi, L., Giordano, P., Giordano, E., Giordano, B., Gioria, G. M., Giugliano, R., Grassi, E. A., Greco, A., Greco, L., Grilletti, N., Grimaldi, N., Grisetti, G., Groppelli, G., Gualtieri, L., Guarducci, M., Guastella, G., Guerra, M., Guerrini, F., Guglielmini, A., Guido, A., Gulotta, P., Iacono, E., Iadarola, G., Ianiro, G., Iarussi, V., Ieluzzi, M. L., Ierardi, C., Ingaldi, F., Interlandi, S., Iocca, M., Iorno, A., Ioverno, E., Iurato, R., La Pace, L., La Piscopia, C., La Selva, R., Lafratta, M., Lamparelli, M., Lanaro, G., Lancerotto, R., Larcher, M., Lassandro, M., Lattuada, G., Laurino, P., Lefons, C., Legrottaglie, F., Lemma, A., Leone, D., Leone, F., Leso, A., Leuzzi, G., Levato, G., Libardi, L., Libralesso, N., Licini, P. I., Licursi, G., Lidonnici, F., Lillo, C., Liveri, L., Livio, A., Loiero, R. A., Loison, M., Lombardo, G., Lombardo, T., Lomunno, V., Lomuscio, S., Lonedo, A., Longo, E., Longoni, P., Lora, L., Lotterio, A., Lucatello, L., Luongo, A., Lupoli, M., Macchia, C., Macri, G., Mafessanti, M., Maggialetti, V., Maggioni, A., Magnani, M., Maiellaro, G., Mancuso, A., Maniglio, A. R., Mannari, G. L., Manni, A., Manocchio, B., Mao, M., Maranò, A., Maraone, E., Marascio, D., Marcheselli, P., Marchetto, B., Marchetto, S., Marchi, A., Marchi, G. L., Mariano, C., Marinacci, S., Marinelli, S., Marini, G., Marra, V. C., Marrali, F., Marseglia, C., Martello, G., Martino, C., Martino, G., Martino, M., Marulli, C. F., Maruzzi, G., Marzotti, A., Mascheroni, G., Mascolo, P., Masoch, G., Masone, R., Massa, E., Massa, L., Massafra, M., Massi, M., Massignani, D. M., Matarese, A. M., Matini, G., Mauro, R., Mazzi, M., Mazzillo, A., Mazzocato, E., Mazzoleni, N. S., Mazzone, A., Melacci, A., Mele, E., Meliota, P., Menaspà, S., Meneghello, F., Merola, G., Merone, L., Metrucci, A., Mezzina, V., Micchi, A., Michielon, A., Migliore, N., Minero, G., Minotta, F., Mirandola, C., Mistrorigo, S., Modafferi, L., Moitre, R., Mola, E., Monachese, C., Mongiardini, C., Montagna, F., Montani, M., Montemurno, I., Montolli, R., Montorsi, S., Montresor, M., Monzani, M. G., Morabito, F., Mori, G., Moro, A., Mosca, M. F., Motti, F., Muddolon, L., Mugnai, M., Muscas, F., Naimoli, F., Nanci, G., Nargi, E., Nasorri, R., Nastrini, G., Negossi, M., Negrini, A., Negroni, A., Neola, V., Niccolini, F., Niro, C. M., Nosengo, C., Novella, G., Nuti, C., Obici, F., Olita, C., Oliverio, S. S., Olivieri, I., Oriente, S., Orlando, G., Paci, C., Pagano, G., Pagliara, C., Paita, G., Paladini, G., Paladino, G., Palano, T., Palatella, A., Palermo, P., Palmisano, M., Pando, P., Panessa, P., Panigo, F., Panozzo, G., Panvini, F., Panzieri, F., Panzino, A., Panzitta, F., Paoli, N., Papagna, R., Papaleo, M. G., Papalia, G., Parisi, R., Parotti, N., Parravicini, D., Passarella, P., Pastore, G. A., Patafio, M., Pavone, P., Pedroli, W., Pedroni, M., Pelligra, G., Pellizzari, M., Penati, A., Perlot, M., Perrone, A., Perrone, G., Peruzzi, P., Peselli, C., Petracchini, L., Petrera, L., Petrone, S., Peverelli, C., Pianorsi, F., Piazza, G. P., Piazzolla, G., Picci, A., Pienabarca, G., Pietronigro, T. P., Pignocchino, P., Pilone, R., Pinto, D., Pirovano, E., Pirrotta, D., Pisante, V., Pitotto, P., Pittari, L., Piva, A., Pizzoglio, A., Plantera, O. R., Plebani, W., Plessi, S., Podrecca, D., Poerio, V., Poggiani, F., Pogliani, W., Poli, L., Poloni, F. G., Porcelli, R., Porto, S., Pranzo, L., Prevedello, C., Profeta, C., Profico, D., Punzi, A., Quaglia, G. M., Racano, M., Raccone, A., Radice, F., Raho, C. A., Raimondi, R., Rainò, M., Ramponi, R., Ramunni, A., Ramunni, A. L., Ravasio, F., Ravera, M., Re Sartò, G., Rebustello, G., Regazzoli, S., Restelli, C., Rezzonico, M., Ricchiuto, F., Rigo, S., Rigon, G., Rigon, R., Rinaldi, O. V., Rinaldi, M., Risplendente, P. G., Rispoli, M., Riundi, R., Riva, M. G., Rizzi, A. L., Rizzi, D., Rizzo, L. D., Rocchi, L., Rondinone, B., Rosa, B., Rosati, F., Roselli, F., Rossetti, A., Rossetti, C., Rossi, R., Rossi, P. R., Rossi, A., Rossi, C. L., Rossitto, A., Ruffini, R., Ruffo, A., Ruggio, S., Ruo, M., Russo, B., Russo, L., Russo, R., Russo, S., Russo, U., Russo, V., Ruta, G., Sacchi, F., Sacco Botto, F., Saia, A., Salladini, G., Salmoiraghi, S., Saluzzo, F., Salvatore, C., Salvatori, E., Salvio, G., Sandri, P., Sandrini, T., Sangermano, V., Santoni, N., Saracino, A. D., Saracino, A., Sarasin, P., Sardo Infirri, C., Sarrì, B., Sartori, G., Sartori, N., Sauro, C., Scaglioni, M., Scalfi, C., Scamardella, A. M., Scandale, G., Scandone, L., Scannavini, G., Scarati, R., Scardi, A., Scarpa, F. M., Scazzi, P., Schifone, A., Schiroso, G., Scigliano, G., Scilla, A., Sciortino, M., Scolaro, G., Scollo, E., Scorretti, G., Sellitti, R., Selmo, A., Selvaggio, G., Sempio, A., Seren, F., Serio, L., Serra, C., Serra, L., Siciliano, D., Sideri, A., Sighele, M., Signore, R., Siliberto, F., Silvestro, M., Simioni, G., Simmini, G., Simonato, L., Sinchetto, F., Sizzano, E., Smajato, G., Smaldone, M., Sola, G., Sordillo, L., Sovran, C. S., Spagnul, P., Spanò, F., Sproviero, S., Squintani, A., Stella, L., Stilo, V., Stocchiero, B., Stornello, M. C., Stracka, G., Strada, S., Stranieri, G., Stucci, N., Stufano, N., Suppa, A., Susca, V. 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A., Zambon, N., Zammarrelli, A., Zanaboni, A., Zane, D., Zanetti, B., Zanibellato, R., Zappetti, M., Zappone, P., Zerilli, G., Zirino, V., Zoccali, R., Zuin, F., Altomonte, M., Anelli, N., Angiò, F., Annale, P., Antonacci, S., Anzilotta, R., Bano, F., Basadonna, O., Beduschi, L., Becagli, P., Bellotti, G., Blotta, C., Bruno, G., Cappuccini, A., Caramatti, S., Cariolato, M. P., Castellana, M., Castellani, L., Catania, R., Chielli, A., Chinellato, A., Ciaccia, A., Clerici, E., Cocci, A., Costanzo, G., D’Ercole, F., De Stefano, G., Decè, F., Di Cicco, N., Di Marco, A., Donati Sarti, C., Draghi, E., Dusi, G., Esposito, V., Ferraro, L., Ferretti, A., Ferri, E., Foggetti, L., Foglia, A., Fonzi, E., Frau, G., Fuoco, M. R., Furci, G., Gallo, L., Garra, V., Giannini, A., Gris, A., Iacovino, R., Interrigi, R., Joppi, R., Laner, B., La Fortezza, G., La Padula, A., Lista, M. R., Lupi, G., Maffei, D., Maggioni, G., Magnani, L., Marrazzo, E., Marcon, L., Marinò, V., Maroni, A., Martinelli, C., Mastandrea, E., Mastropierro, F., Meo, A. T., Mero, P., Minesso, E., Moschetta, V., Mosele, E., Nanni, C., Negretti, A., Nisticò, C., Orsini, A., Osti, M., Pacilli, M. C., Pennestre, C., Picerno, G., Piol, K., Pivano, L., Pizzuti, E., Poggi, L., Poidomani, I., Pozzetto, M., Presti, M. L., Ravani, R., Recalenda, V., Romagnuolo, F., Rossignoli, S., Rossin, E., Sabatella, C., Sacco, F., Sanità, F., Sansone, E., Servadei, F., Sisto, M. T., Sorio, A., Sorrentino, A., Spinelli, E., Spolaor, A., Squillacioti, A., Stella, P., Talerico, A., Todisco, C., Vadino, M., Zuliani, C., and Risk & Prevention Collaborative Group
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- 2017
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16. 1883P Impact of geriatrician-implemented Interventions on chemotherapy (CT) delivery in vulnerable elderly patients with early or advanced solid tumors: The GIVE trial
- Author
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Risi, E., Brunello, A., Biagioni, C., Calvani, D., Di Donato, S., Moretti, E., Bergamo, F., Pozzessere, D., Zafarana, E., Baldi, G.G., Mori, E., Palmieri, V.E., Luciani, A., Fratino, L., Del Monte, F., Malorni, L., Becheri, D., Battisti, N.M.L., Mottino, G., and Biganzoli, L.
- Published
- 2024
- Full Text
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17. 533P First-line treatment in older patients with metastatic colorectal cancer: A large real-world study
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Basile, D., Bergamo, F., Ongaro, E., Cinausero, M., Conca, V., Ambrosini, M., Lucchetti, J., rosati, G., Avallone, A., Di Paolo, G., Lai, E., Lutrino, E.S., Di Nardo, P., Zurlo, I.V., Cortese, C., carullo, M., Leo, S., Di Donato, S., Pietrantonio, F., and Aprile, G.
- Published
- 2024
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18. The Mitochondrial Machinery
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Di Donato, S., Desnuelle, Claude, and DiMauro, Salvatore
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- 2002
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19. Surgical treatment of sacral chordoma: survival and prognostic factors
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Ruosi, C., Colella, G., Di Donato, S. L., Granata, F., Di Salvatore, M. G., and Fazioli, F.
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- 2015
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20. AB0142 EVIDENCE OF TYPE I INTERFERON ACTIVATION DURING VASCULAR MANIFESTATIONS OF SYSTEMIC SCLEROSIS
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Di Donato, S., primary, Hughes, M., additional, Abignano, G., additional, Lettieri, G., additional, Ross, R., additional, De Lorenzis, E., additional, O’Connor, P., additional, Kubassova, O., additional, and Del Galdo, F., additional
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- 2022
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21. POS0876 SERUM INTERFERON SCORE PREDICTS SEVERITY OF PATIENT REPORTED HAND DISABILITY IN SYSTEMIC SCLEROSIS
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De Lorenzis, E., primary, Kakkar, V., additional, Ross, R., additional, DI Donato, S., additional, Barnes, T., additional, Saleem, B., additional, Herrick, A., additional, Nisar, M., additional, Morley, C., additional, Douglas, K., additional, Denton, C. P., additional, Derrett-Smith, E., additional, Helliwell, P., additional, and Del Galdo, F., additional
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- 2022
- Full Text
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22. AB0261 CARDIOMETABOLIC COMORBIDITIES MAY IDENTIFY A MORE SEVERE SUBSET OF RHEUMATOID ARTHRITIS, RESULTS FROM A “REAL-LIFE” STUDY
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Ruscitti, P., primary, Conforti, A., additional, DI Muzio, C., additional, Currado, D., additional, Navarini, L., additional, Pavlych, V., additional, DI Cola, I., additional, Sensini, F., additional, Biaggi, A., additional, DI Donato, S., additional, Marino, A., additional, Lorusso, S., additional, Ursini, F., additional, Giacomelli, R., additional, and Cipriani, P., additional
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- 2022
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23. AB1182 SPECIALIZED PRO-RESOLVING MEDIATORS (SPMS) AND INFLAMMATORY NETWORKS IN PATIENTS AFFECTED BY ADULT ONSET STILL’S DISEASE (AOSD) AND COVID-19
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Navarini, L., primary, Vomero, M., additional, Berardiucrti, O., additional, Currado, D., additional, Marino, A., additional, Biaggi, A., additional, DI Donato, S., additional, Ursini, F., additional, Ruscitti, P., additional, Meliconi, R., additional, Cipriani, P., additional, Iagnocco, A., additional, Afeltra, A., additional, and Giacomelli, R., additional
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- 2022
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24. Answer to the Letter to the Editor of J. Li et al. concerning “Surgical treatment of sacral chordoma: survival and prognostic factors” by C. Ruosi et al. (Eur Spine J; 2015; 24(Suppl 7):S912–S917)
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Ruosi, C., Colella, G., Di Donato, S. L., Granata, F., Di Salvatore, M. G., and Fazioli, F.
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- 2017
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25. Early tumor shrinkage and depth of response predict long-term outcome in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab: results from phase III TRIBE trial by the Gruppo Oncologico del Nord Ovest
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Cremolini, C., Loupakis, F., Antoniotti, C., Lonardi, S., Masi, G., Salvatore, L., Cortesi, E., Tomasello, G., Spadi, R., Zaniboni, A., Tonini, G., Barone, C., Vitello, S., Longarini, R., Bonetti, A., DʼAmico, M., Di Donato, S., Granetto, C., Boni, L., and Falcone, A.
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- 2015
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26. P-173 Outcomes of palliative gastrectomy in 549 asymptomatic patients with advanced gastric cancer
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Fanotto, V., Fontanella, C., Cordio, S., Pasquini, G., Baretti, M., Filippi, R., Rosati, G., Santini, D., Giampieri, R., Di Donato, S., Tomasello, G., Brunetti, O., Caporale, M., Bergamo, F., Avallone, A., Scartozzi, M., Lutrino, S., Melisi, D., Antonuzzo, L., Pellegrino, A., and Aprile, G.
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- 2016
- Full Text
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27. Measurement of the Higgs boson production rate in association with top quarks in final states with electrons, muons, and hadronically decaying tau leptons at [Formula: see text]
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Sirunyan, A. M. Tumasyan, A. Adam, W. Bergauer, T. Dragicevic, M. Erö, J. Valle, A. Escalante Del Frühwirth, R. Jeitler, M. Krammer, N. Lechner, L. Liko, D. Mikulec, I. Pitters, F. M. Rad, N. Schieck, J. Schöfbeck, R. Spanring, M. Templ, S. Waltenberger, W. Wulz, C.-E. Zarucki, M. Chekhovsky, V. Litomin, A. Makarenko, V. Gonzalez, J. Suarez Darwish, M. R. De Wolf, E. A. Croce, D. Di Janssen, X. Kello, T. Lelek, A. Pieters, M. Sfar, H. Rejeb Haevermaet, H. Van Mechelen, P. Van Putte, S. Van Remortel, N. Van Blekman, F. Bols, E. S. Chhibra, S. S. D'Hondt, J. De Clercq, J. Lontkovskyi, D. Lowette, S. Marchesini, I. Moortgat, S. Morton, A. Müller, D. Python, Q. Tavernier, S. Doninck, W. Van Mulders, P. Van Beghin, D. Bilin, B. Clerbaux, B. De Lentdecker, G. Dorney, B. Favart, L. Grebenyuk, A. Kalsi, A. K. Makarenko, I. Moureaux, L. Pétré, L. Popov, A. Postiau, N. Starling, E. Thomas, L. Velde, C. Vander Vanlaer, P. Vannerom, D. Wezenbeek, L. Cornelis, T. Dobur, D. Gruchala, M. Khvastunov, I. Niedziela, M. Roskas, C. Skovpen, K. Tytgat, M. Verbeke, W. Vermassen, B. Vit, M. Bruno, G. Bury, F. Caputo, C. David, P. Delaere, C. Delcourt, M. Donertas, I. S. Faham, H. El Giammanco, A. Lemaitre, V. Mondal, K. Prisciandaro, J. Taliercio, A. Teklishyn, M. Vischia, P. Wertz, S. Wuyckens, S. Alves, G. A. Hensel, C. Moraes, A. Júnior, W. L. Aldá Chagas, E. Belchior Batista Das Malbouisson, H. Brandao Carvalho, W. Chinellato, J. Coelho, E. Da Costa, E. M. Da Silveira, G. G. De Jesus Damiao, D. De Souza, S. Fonseca Martins, J. Figueiredo, D. Matos Jaime, M. Medina Herrera, C. Mora Mundim, L. Nogima, H. Teles, P. Rebello Rosas, L. J. Sanchez Santoro, A. Amaral, S. M. Silva Do Sznajder, A. Thiel, M. Da Silva De Araujo, F. Torres Pereira, A. Vilela Bernardes, C. A. Calligaris, L. Tomei, T. R. Fernandez Perez Gregores, E. M. Lemos, D. S. Mercadante, P. G. Novaes, S. F. Padula, Sandra S. Aleksandrov, A. Antchev, G. Atanasov, I. Hadjiiska, R. Iaydjiev, P. Misheva, M. Rodozov, M. Shopova, M. Sultanov, G. Dimitrov, A. Ivanov, T. Litov, L. Pavlov, B. Petkov, P. Petrov, A. Cheng, T. Fang, W. Guo, Q. Wang, H. Yuan, L. Ahmad, M. Bauer, G. Hu, Z. Wang, Y. Yi, K. Chapon, E. Chen, G. M. Chen, H. S. Chen, M. Javaid, T. Kapoor, A. Leggat, D. Li, B. Liao, H. Liu, Z.-A. Sharma, R. Spiezia, A. Tao, J. Thomas-Wilsker, J. Wang, J. Zhang, H. Zhang, S. Zhao, J. Agapitos, A. Ban, Y. Chen, C. Huang, Q. Levin, A. Li, Q. Lu, M. Lyu, X. Mao, Y. Qian, S. J. Wang, D. Wang, Q. Xiao, J. You, Z. Gao, X. Xiao, M. Avila, C. Cabrera, A. Florez, C. Fraga, J. Sarkar, A. Delgado, M. A. Segura Jaramillo, J. Guisao, J. Mejia Ramirez, F. Alvarez, J. D. Ruiz González, C. A. Salazar Arbelaez, N. Vanegas Giljanovic, D. Godinovic, N. Lelas, D. Puljak, I. Antunovic, Z. Kovac, M. Sculac, T. Brigljevic, V. Ferencek, D. Majumder, D. Roguljic, M. Starodumov, A. Susa, T. Ather, M. W. Attikis, A. Erodotou, E. Ioannou, A. Kole, G. Kolosova, M. Konstantinou, S. Mousa, J. Nicolaou, C. Ptochos, F. Razis, P. A. Rykaczewski, H. Saka, H. Tsiakkouri, D. Finger, M. Finger, M. Jr Kveton, A. Tomsa, J. Ayala, E. Jarrin, E. Carrera Abdalla, H. Assran, Y. Khalil, S. Mahmoud, M. A. Mohammed, Y. Bhowmik, S. De Oliveira, A. Carvalho Antunes Dewanjee, R. K. Ehataht, K. Kadastik, M. Raidal, M. Veelken, C. Eerola, P. Forthomme, L. Kirschenmann, H. Osterberg, K. Voutilainen, M. Brücken, E. Garcia, F. Havukainen, J. Karimäki, V. Kim, M. S. Kinnunen, R. Lampén, T. Lassila-Perini, K. Lehti, S. Lindén, T. Siikonen, H. Tuominen, E. Tuominiemi, J. Luukka, P. Tuuva, T. Amendola, C. Besancon, M. Couderc, F. Dejardin, M. Denegri, D. Faure, J. L. Ferri, F. Ganjour, S. Givernaud, A. Gras, P. de Monchenault, G. Hamel Jarry, P. Lenzi, B. Locci, E. Malcles, J. Rander, J. Rosowsky, A. Sahin, M. Ö Savoy-Navarro, A. Titov, M. Yu, G. B. Ahuja, S. Beaudette, F. Bonanomi, M. Perraguin, A. Buchot Busson, P. Charlot, C. Davignon, O. Diab, B. Falmagne, G. de Cassagnac, R. Granier Hakimi, A. Kucher, I. Lobanov, A. Perez, C. Martin Nguyen, M. Ochando, C. Paganini, P. Rembser, J. Salerno, R. Sauvan, J. B. Sirois, Y. Zabi, A. Zghiche, A. Agram, J.-L. Andrea, J. Bloch, D. Bourgatte, G. Brom, J.-M. Chabert, E. C. Collard, C. Fontaine, J.-C. Gelé, D. Goerlach, U. Grimault, C. Bihan, A.-C. Le Hove, P. Van Asilar, E. Beauceron, S. Bernet, C. Boudoul, G. Camen, C. Carle, A. Chanon, N. Contardo, D. Depasse, P. Mamouni, H. El Fay, J. Gascon, S. Gouzevitch, M. Ille, B. Jain, Sa Laktineh, I. B. Lattaud, H. Lesauvage, A. Lethuillier, M. Mirabito, L. Torterotot, L. Touquet, G. Donckt, M. Vander Viret, S. Khvedelidze, A. Tsamalaidze, Z. Feld, L. Klein, K. Lipinski, M. Meuser, D. Pauls, A. Preuten, M. Rauch, M. P. Schulz, J. Teroerde, M. Eliseev, D. Erdmann, M. Fackeldey, P. Fischer, B. Ghosh, S. Hebbeker, T. Hoepfner, K. Keller, H. Mastrolorenzo, L. Merschmeyer, M. Meyer, A. Mocellin, G. Mondal, S. Mukherjee, S. Noll, D. Novak, A. Pook, T. Pozdnyakov, A. Rath, Y. Reithler, H. Roemer, J. Schmidt, A. Schuler, S. C. Sharma, A. Wiedenbeck, S. Zaleski, S. Dziwok, C. Flügge, G. Ahmad, W. Haj Hlushchenko, O. Kress, T. Nowack, A. Pistone, C. Pooth, O. Roy, D. Sert, H. Stahl, A. Ziemons, T. Petersen, H. Aarup Martin, M. Aldaya Asmuss, P. Babounikau, I. Baxter, S. Behnke, O. Martínez, A. Bermúdez Anuar, A. A. Bin Borras, K. Botta, V. Brunner, D. Campbell, A. Cardini, A. Connor, P. Rodríguez, S. Consuegra Danilov, V. De Wit, A. Defranchis, M. M. Didukh, L. Damiani, D. Domínguez Eckerlin, G. Eckstein, D. Eichhorn, T. Banos, L. I. Estevez Gallo, E. Geiser, A. Giraldi, A. Grohsjean, A. Guthoff, M. Harb, A. Jafari, A. Jomhari, N. Z. Jung, H. Kasem, A. Kasemann, M. Kaveh, H. Kleinwort, C. Knolle, J. Krücker, D. Lange, W. Lenz, T. Lidrych, J. Lipka, K. Lohmann, W. Madlener, T. Mankel, R. Melzer-Pellmann, I.-A. Metwally, J. Meyer, A. B. Meyer, M. Missiroli, M. Mnich, J. Mussgiller, A. Myronenko, V. Otarid, Y. Adán, D. Pérez Pflitsch, S. K. Pitzl, D. Raspereza, A. Saggio, A. Saibel, A. Savitskyi, M. Scheurer, V. Schwanenberger, C. Singh, A. Ricardo, R. E. Sosa Tonon, N. Turkot, O. Vagnerini, A. De Klundert, M. Van Walsh, R. Walter, D. Wen, Y. Wichmann, K. Wissing, C. Wuchterl, S. Zenaiev, O. Zlebcik, R. Aggleton, R. Bein, S. Benato, L. Benecke, A. De Leo, K. Dreyer, T. Ebrahimi, A. Eich, M. Feindt, F. Fröhlich, A. Garbers, C. Garutti, E. Gunnellini, P. Haller, J. Hinzmann, A. Karavdina, A. Kasieczka, G. Klanner, R. Kogler, R. Kutzner, V. Lange, J. Lange, T. Malara, A. Niemeyer, C. E. N. Nigamova, A. Rodriguez, K. J. Pena Rieger, O. Schleper, P. Schumann, S. Schwandt, J. Schwarz, D. Sonneveld, J. Stadie, H. Steinbrück, G. Vormwald, B. Zoi, I. Bechtel, J. Berger, T. Butz, E. Caspart, R. Chwalek, T. De Boer, W. Dierlamm, A. Droll, A. Morabit, K. El Faltermann, N. Flöh, K. Giffels, M. Gottmann, A. Hartmann, F. Heidecker, C. Husemann, U. Katkov, I. Keicher, P. Koppenhöfer, R. Maier, S. Metzler, M. Mitra, S. Müller, Th Musich, M. Quast, G. Rabbertz, K. Rauser, J. Savoiu, D. Schäfer, D. 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Nahn, S. O'Dell, V. Papadimitriou, V. Pedro, K. Pena, C. Prokofyev, O. Ravera, F. Hall, A. Reinsvold Ristori, L. Schneider, B. Sexton-Kennedy, E. Smith, N. Soha, A. Spalding, W. J. Spiegel, L. Stoynev, S. Strait, J. Taylor, L. Tkaczyk, S. Tran, N. V. Uplegger, L. Vaandering, E. W. Weber, H. A. Woodard, A. Acosta, D. Avery, P. Bourilkov, D. Cadamuro, L. Cherepanov, V. Errico, F. Field, R. D. Guerrero, D. Joshi, B. M. Kim, M. Konigsberg, J. Korytov, A. Lo, K. H. Matchev, K. Menendez, N. Mitselmakher, G. Rosenzweig, D. Shi, K. Sturdy, J. Wang, J. Wang, S. Zuo, X. Adams, T. Askew, A. Diaz, D. Habibullah, R. Hagopian, S. Hagopian, V. Johnson, K. F. Khurana, R. Kolberg, T. Martinez, G. Prosper, H. Schiber, C. Yohay, R. Zhang, J. Baarmand, M. M. Butalla, S. Elkafrawy, T. Hohlmann, M. Noonan, D. Rahmani, M. Saunders, M. Yumiceva, F. Adams, M. R. Apanasevich, L. Gonzalez, H. Becerril Cavanaugh, R. Chen, X. Dittmer, S. Evdokimov, O. Gerber, C. E. Hangal, D. A. Hofman, D. J. Mills, C. Oh, G. Roy, T. Tonjes, M. B. Varelas, N. Viinikainen, J. Wang, X. Wu, Z. Ye, Z. Alhusseini, M. Dilsiz, K. Durgut, S. Gandrajula, R. P. Haytmyradov, M. Khristenko, V. Köseyan, O. K. Merlo, J.-P. Mestvirishvili, A. Moeller, A. Nachtman, J. Ogul, H. Onel, Y. Ozok, F. Penzo, A. Snyder, C. Tiras, E. Wetzel, J. Amram, O. Blumenfeld, B. Corcodilos, L. Eminizer, M. Gritsan, A. V. Kyriacou, S. Maksimovic, P. Mantilla, C. Roskes, J. Swartz, M. Vámi, T. Á Barrera, C. Baldenegro Baringer, P. Bean, A. Bylinkin, A. Isidori, T. Khalil, S. King, J. Krintiras, G. Kropivnitskaya, A. Lindsey, C. Minafra, N. Murray, M. Rogan, C. Royon, C. Sanders, S. Schmitz, E. Takaki, J. D. Tapia Wang, Q. Williams, J. Wilson, G. Duric, S. Ivanov, A. Kaadze, K. Kim, D. Maravin, Y. Mitchell, T. Modak, A. Mohammadi, A. Rebassoo, F. Wright, D. Adams, E. Baden, A. Baron, O. Belloni, A. Eno, S. C. Feng, Y. Hadley, N. J. Jabeen, S. Jeng, G. Y. Kellogg, R. G. Koeth, T. Mignerey, A. C. Nabili, S. Seidel, M. Skuja, A. Tonwar, S. C. Wang, L. Wong, K. Abercrombie, D. Allen, B. Bi, R. Brandt, S. Busza, W. Cali, I. A. Chen, Y. D'Alfonso, M. Ceballos, G. Gomez Goncharov, M. Harris, P. Hsu, D. Hu, M. Klute, M. Kovalskyi, D. Krupa, J. Lee, Y.-J. Luckey, P. D. Maier, B. Marini, A. C. Mcginn, C. Mironov, C. Narayanan, S. Niu, X. Paus, C. Rankin, D. Roland, C. Roland, G. Shi, Z. Stephans, G. S. F. Sumorok, K. Tatar, K. Velicanu, D. Wang, J. Wang, T. W. Wang, Z. Wyslouch, B. Chatterjee, R. M. Evans, A. Hansen, P. Hiltbrand, J. Jain, Sh Krohn, M. Kubota, Y. Lesko, Z. Mans, J. Revering, M. Rusack, R. Saradhy, R. Schroeder, N. Strobbe, N. Wadud, M. A. Acosta, J. G. Oliveros, S. Bloom, K. Chauhan, S. Claes, D. R. Fangmeier, C. Finco, L. Golf, F. Fernández, J. R. González Joo, C. Kravchenko, I. Siado, J. E. Snow, G. R. Tabb, W. Yan, F. Agarwal, G. Bandyopadhyay, H. Harrington, C. Hay, L. Iashvili, I. Kharchilava, A. McLean, C. Nguyen, D. Pekkanen, J. Rappoccio, S. Roozbahani, B. Alverson, G. Barberis, E. Freer, C. Haddad, Y. Hortiangtham, A. Li, J. Madigan, G. Marzocchi, B. Morse, D. M. Nguyen, V. Orimoto, T. Parker, A. Skinnari, L. Tishelman-Charny, A. Wamorkar, T. Wang, B. Wisecarver, A. Wood, D. Bhattacharya, S. Bueghly, J. Chen, Z. Gilbert, A. Gunter, T. Hahn, K. A. Odell, N. Schmitt, M. H. Sung, K. Velasco, M. Bucci, R. Dev, N. Goldouzian, R. Hildreth, M. Anampa, K. Hurtado Jessop, C. Karmgard, D. J. Lannon, K. Loukas, N. Marinelli, N. Mcalister, I. Meng, F. Mohrman, K. Musienko, Y. Ruchti, R. Siddireddy, P. Taroni, S. Wayne, M. Wightman, A. Wolf, M. Zygala, L. Alimena, J. Bylsma, B. Cardwell, B. Durkin, L. S. Francis, B. Hill, C. Lefeld, A. Winer, B. L. Yates, B. R. Bonham, B. Das, P. Dezoort, G. Dropulic, A. Elmer, P. Greenberg, B. Haubrich, N. Higginbotham, S. Kalogeropoulos, A. Kopp, G. Kwan, S. Lange, D. Lucchini, M. T. Luo, J. Marlow, D. Mei, K. Ojalvo, I. Olsen, J. Palmer, C. Piroué, P. Stickland, D. Tully, C. Malik, S. Norberg, S. Barnes, V. E. Chawla, R. Das, S. Gutay, L. Jones, M. Jung, A. W. Negro, G. Neumeister, N. Peng, C. C. Piperov, S. Purohit, A. Qiu, H. Schulte, J. F. Stojanovic, M. Trevisani, N. Wang, F. Wildridge, A. Xiao, R. Xie, W. Dolen, J. Parashar, N. Baty, A. Dildick, S. Ecklund, K. M. Freed, S. Geurts, F. J. M. Kilpatrick, M. Kumar, A. Li, W. Padley, B. P. Redjimi, R. Roberts, J. Rorie, J. Shi, W. Leiton, A. G. Stahl Bodek, A. de Barbaro, P. Demina, R. Dulemba, J. L. Fallon, C. Ferbel, T. Galanti, M. Garcia-Bellido, A. Hindrichs, O. Khukhunaishvili, A. Ranken, E. Taus, R. Chiarito, B. Chou, J. P. Gandrakota, A. Gershtein, Y. Halkiadakis, E. Hart, A. Heindl, M. Hughes, E. Kaplan, S. Karacheban, O. Laflotte, I. Lath, A. Montalvo, R. Nash, K. Osherson, M. Salur, S. Schnetzer, S. Somalwar, S. Stone, R. Thayil, S. A. Thomas, S. Wang, H. Acharya, H. Delannoy, A. G. Spanier, S. Bouhali, O. Dalchenko, M. Delgado, A. Eusebi, R. Gilmore, J. Huang, T. Kamon, T. Kim, H. Luo, S. Malhotra, S. Mueller, R. Overton, D. Perniè, L. Rathjens, D. Safonov, A. Akchurin, N. Damgov, J. Hegde, V. Kunori, S. Lamichhane, K. Lee, S. W. Mengke, T. Muthumuni, S. Peltola, T. Undleeb, S. Volobouev, I. Wang, Z. Whitbeck, A. Appelt, E. Greene, S. Gurrola, A. Janjam, R. Johns, W. Maguire, C. Melo, A. Ni, H. Padeken, K. Romeo, F. Sheldon, P. Tuo, S. Velkovska, J. Arenton, M. W. Cox, B. Cummings, G. Hakala, J. Hirosky, R. Joyce, M. Ledovskoy, A. Li, A. Neu, C. Tannenwald, B. Wang, Y. Wolfe, E. Xia, F. Karchin, P. E. Poudyal, N. Thapa, P. Black, K. Bose, T. Buchanan, J. Caillol, C. Dasu, S. De Bruyn, I. Everaerts, P. Galloni, C. He, H. Herndon, M. Hervé, A. Hussain, U. Lanaro, A. Loeliger, A. Loveless, R. Sreekala, J. Madhusudanan Mallampalli, A. Pinna, D. Savin, A. Shang, V. Sharma, V. Smith, W. H. Teague, D. Trembath-Reichert, S. Vetens, W.
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High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
The rate for Higgs ( H ) bosons production in association with either one ( tH ) or two ( tt¯H ) top quarks is measured in final states containing multiple electrons, muons, or tau leptons decaying to hadrons and a neutrino, using proton-proton collisions recorded at a center-of-mass energy of 13 TeV by the CMS experiment. The analyzed data correspond to an integrated luminosity of 137 fb-1 . The analysis is aimed at events that contain H → WW , H → ττ , or H → ZZ decays and each of the top quark(s) decays either to lepton+jets or all-jet channels. Sensitivity to signal is maximized by including ten signatures in the analysis, depending on the lepton multiplicity. The separation among tH , tt¯H , and the backgrounds is enhanced through machine-learning techniques and matrix-element methods. The measured production rates for the tt¯H and tH signals correspond to 0.92 ± 0.19 (stat)-0.13+0.17 (syst) and 5.7 ± 2.7 (stat) ± 3.0 (syst) of their respective standard model (SM) expectations. The corresponding observed (expected) significance amounts to 4.7 (5.2) standard deviations for tt¯H , and to 1.4 (0.3) for tH production. Assuming that the Higgs boson coupling to the tau lepton is equal in strength to its expectation in the SM, the coupling yt of the Higgs boson to the top quark divided by its SM expectation, κt = yt/ytSM , is constrained to be within - 0.9 {\textless} κt {\textless} - 0.7 or 0.7 {\textless} κt {\textless} 1.1 , at 95\% confidence level. This result is the most sensitive measurement of the tt¯H production rate to date.
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- 2021
28. A validated prognostic classifier for V600EBRAF-mutated metastatic colorectal cancer: the ‘BRAF BeCool’ study
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Loupakis F., Intini R., Cremolini C., Orlandi A., Sartore-Bianchi A., Pietrantonio F., Pella N., Spallanzani A., Dell'Aquila E., Scartozzi M., De Luca E., Rimassa L., Formica V., Leone F., Calvetti L., Aprile G., Antonuzzo L., Urbano F., Prenen H., Negri F., Di Donato S., Buonandi P., Tomasello G., Avallone A., Zustovich F., Moretto R., Antoniotti C., Salvatore L., Calegari M. A., Siena S., Morano F., Ongaro E., Cascinu S., Santini D., Ziranu P., Schirripa M., Buggin F., Prete A. A., Depetris I., Biason P., Lonardi S., Zagonel V., Fassan M., Di Maio M., Loupakis, F., Intini, R., Cremolini, C., Orlandi, A., Sartore-Bianchi, A., Pietrantonio, F., Pella, N., Spallanzani, A., Dell'Aquila, E., Scartozzi, M., De Luca, E., Rimassa, L., Formica, V., Leone, F., Calvetti, L., Aprile, G., Antonuzzo, L., Urbano, F., Prenen, H., Negri, F., Di Donato, S., Buonandi, P., Tomasello, G., Avallone, A., Zustovich, F., Moretto, R., Antoniotti, C., Salvatore, L., Calegari, M. A., Siena, S., Morano, F., Ongaro, E., Cascinu, S., Santini, D., Ziranu, P., Schirripa, M., Buggin, F., Prete, A. A., Depetris, I., Biason, P., Lonardi, S., Zagonel, V., Fassan, M., and Di Maio, M.
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Adult ,Male ,Proto-Oncogene Proteins B-raf ,Scoring system ,DNA Mutational Analysis ,Metastases ,V600E ,BRAF ,Colorectal cancer ,Prognostic markers ,Risk Assessment ,Young Adult ,Predictive Value of Tests ,Risk Factors ,Biomarkers, Tumor ,Humans ,Genetic Predisposition to Disease ,Neoplasm Metastasis ,Aged ,Retrospective Studies ,Aged, 80 and over ,Middle Aged ,Prognosis ,Phenotype ,Italy ,Mutation ,Female ,Colorectal Neoplasms - Abstract
Background: Despite the well-known negative prognostic value of the V600EBRAF mutation in patients with metastatic colorectal cancer (mCRC), its outcome is quite heterogeneous, and the basis for this prognostic heterogeneity should be better defined. Methods: Two large retrospective series of V600EBRAF-mutated mCRC from 22 institutions served as an exploratory and validation set to develop a prognostic score. The model was internally and externally validated. Results: A total of 395 V600EBRAF-mutated mCRCs were included in the exploratory set. Performance status, CA19.9, lactate dehydrogenase, neutrophil/lymphocyte ratio, grading and liver, lung and nodal involvement emerged as independent prognostic factors for overall survival (OS). Two different scoring systems were built: a ‘complete’ score (0–16) including all significant covariates and a ‘simplified’ score (0–9), based only on clinicopathological covariates, and excluding laboratory values. Adopting the complete score, proportions of patients with a low (0–4), intermediate (5–8) and high (9–16) score were 44.7%, 42.6% and 12.6%, respectively. The median OS was 29.6, 15.5 (hazard ratio [HR] for intermediate vs low risk: 2.16, 95% confidence interval [CI]: 1.44–3.22, p < .001) and 6.6 months (HR for high vs low risk: 4.72, 95% CI: 2.72–8.20, p < .001). Similar results were observed also after adjusting for the type of first-line treatment and adopting the simplified score. The simplified prognostic score derived from the exploratory set was then applied to the validation set for external confirmation. Conclusions: These scoring systems are based on easy-to-collect data and defined specific subgroups with relevant differences in their life expectancy. These tools could be useful in clinical practice, would allow better stratification of patients in clinical trials and may be adopted for proper adjustments in exploratory translational analyses.
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- 2019
29. Spinocerebellar ataxia type 17 (SCA17): Oculomotor phenotype and clinical characterization of 15 Italian patients
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Mariotti, C., Alpini, D., Fancellu, R., Soliveri, P., Grisoli, M., Ravaglia, S., Lovati, C., Fetoni, V., Giaccone, G., Castucci, A., Taroni, F., Gellera, C., and Di Donato, S.
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- 2007
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30. Ataxia with isolated vitamin E deficiency: neurological phenotype, clinical follow-up and novel mutations in TTPAgene in Italian families
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Mariotti, C., Gellera, C., Rimoldi, M., Mineri, R., Uziel, G., Zorzi, G., Pareyson, D., Piccolo, G., Gambi, D., Piacentini, S., Squitieri, F., Capra, R., Castellotti, B., and Di Donato, S.
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- 2004
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31. Molecular Diagnosis of Neurogenetic Disorders: Motoneuron, Peripheral Nerve and Muscle Disorders
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Burgunder, J-M., primary, Schöls, L., additional, Baets, J., additional, Andersen, P., additional, Gasser, T., additional, Szolnoki, Z., additional, Fontaine, B., additional, Van Broeckhoven, C., additional, Di Donato, S., additional, De Jonghe, P., additional, Lynch, T., additional, Mariotti, C., additional, Spinazzola, A., additional, Tabrizi, S. J., additional, Tallaksen, C., additional, Zeviani, M., additional, Harbo, H. F., additional, and Finsterer, J., additional
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- 2011
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32. Molecular Diagnosis of Mitochondrial Disorders
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Finsterer, J., primary, Harbo, H. F., additional, Baets, J., additional, Van Broeckhoven, C., additional, Di Donato, S., additional, Fontaine, B., additional, De Jonghe, P., additional, Lossos, A., additional, Lynch, T., additional, Mariotti, C., additional, Schöls, L., additional, Spinazzola, A., additional, Szolnoki, Z., additional, Tabrizi, S. J., additional, Tallaksen, C., additional, Zeviani, M., additional, Burgunder, J-M., additional, and Gasser, T., additional
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- 2011
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33. Molecular Diagnosis of Channelopathies, Epilepsies, Migraine, Stroke and Dementias
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Burgunder, J-M., primary, Finsterer, J., additional, Szolnoki, Z., additional, Fontaine, B., additional, Baets, J., additional, Van Broeckhoven, C., additional, Di Donato, S., additional, De Jonghe, P., additional, Lynch, T., additional, Mariotti, C., additional, Schöls, L., additional, Spinazzola, A., additional, Tabrizi, S. J., additional, Tallaksen, C., additional, Zeviani, M., additional, Harbo, H. F., additional, and Gasser, T., additional
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- 2011
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34. Molecular Diagnosis of Neurogenetic Disorders: General Issues, Huntington's Disease, Parkinson's Disease and Dystonias
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Harbo, H. F., primary, Finsterer, J., additional, Baets, J., additional, Van Broeckhoven, C., additional, Di Donato, S., additional, Fontaine, B., additional, De Jonghe, P., additional, Lossos, A., additional, Lynch, T., additional, Mariotti, C., additional, Schöls, L., additional, Spinazzola, A., additional, Szolnoki, Z., additional, Tabrizi, S. J., additional, Tallaksen, C., additional, Zeviani, M., additional, Burgunder, J-M., additional, and Gasser, T., additional
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- 2011
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35. Molecular Diagnosis of Ataxias and Spastic Paraplegias
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Gasser, T., primary, Finsterer, J., additional, Baets, J., additional, Van Broeckhoven, C., additional, Di Donato, S., additional, Fontaine, B., additional, De Jonghe, P., additional, Lossos, A., additional, Lynch, T., additional, Mariotti, C., additional, Schöls, L., additional, Spinazzola, A., additional, Szolnoki, Z., additional, Tabrizi, S. J., additional, Tallaksen, C. M. E., additional, Zeviani, M., additional, Burgunder, J-M., additional, and Harbo, H. F., additional
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- 2011
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36. Cerebellar/spinocerebellar syndromes
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Mariotti, C. and Di Donato, S.
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- 2001
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37. The complex clinical and genetic classification of inherited ataxias. II. Autosomal recessive ataxias
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Di Donato, S., Gellera, C., and Mariotti, C.
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- 2001
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38. Disorders related to mitochondrial membranes: Pathology of the respiratory chain and neurodegeneration
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Di Donato, S.
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- 2000
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39. F13 Progressive reduction of plasma 24S-hydroxycholestrol in prodromal HD subjects according with clinical and MRI features in the PREDICT-HD study
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Valerio, L, Di Donato, S, Long, J, Juhl, A, and Paulsen, J
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- 2012
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40. Clinical and molecular studies of 73 Italian families with autosomal dominant cerebellar ataxia type I: SCA1 and SCA2 are the most common genotypes
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Pareyson, Davide, Gellera, Cinzia, Castellotti, Barbara, Antonelli, Antonella, Riggio, Maria Concetta, Mazzucchelli, Franca, Girotti, Floriano, Pietrini, Vladimiro, Mariotti, Caterina, and Di Donato, S.
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- 1999
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41. EFNS guidelines for the molecular diagnosis of neurogenetic disorders: motoneuron, peripheral nerve and muscle disorders
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Burgunder, J.-M., Schöls, L., Baets, J., Andersen, P., Gasser, T., Szolnoki, Z., Fontaine, B., Van Broeckhoven, C., Di Donato, S., De Jonghe, P., Lynch, T., Mariotti, C., Spinazzola, A., Tabrizi, S. J., Tallaksen, C., Zeviani, M., Harbo, H. F., and Finsterer, J.
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- 2011
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42. The complex clinical and genetic classification of inherited ataxias. I. Dominant ataxias
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Di Donato, S.
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- 1998
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43. Cerebral and extra-cerebral cholesterol biosynthesis is impaired in HD patients: P1094
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Leoni, V., Mariotti, C., Nanetti, L., Tommasello, C., Salvatore, E., Di Michele, G., Soletti, F., Bentivoglio, A. R., di Poggio, Bandettini M., Abbruzzese, G., PIacentini, S., Squitieri, F., Valenza, M., Cattaneo, E., and Di Donato, S.
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- 2010
44. EFNS guidelines on the molecular diagnosis of channelopathies, epilepsies, migraine, stroke, and dementias
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Burgunder, J-M., Finsterer, J., Szolnoki, Z., Fontaine, B., Baets, J., Van Broeckhoven, C., Di Donato, S., De Jonghe, P., Lynch, T., Mariotti, C., Schöls, L., Spinazzola, A., Tabrizi, S. J., Tallaksen, C., Zeviani, M., Harbo, H. F., and Gasser, T.
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- 2010
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45. EFNS guidelines on the molecular diagnosis of ataxias and spastic paraplegias
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Gasser, T., Finsterer, J., Baets, J., Van Broeckhoven, C., Di Donato, S., Fontaine, B., De Jonghe, P., Lossos, A., Lynch, T., Mariotti, C., Schöls, L., Spinazzola, A., Szolnoki, Z., Tabrizi, S. J., Tallaksen, C.M.E., Zeviani, M., Burgunder, J-M., and Harbo, H. F.
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- 2010
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46. 12 Group
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PITZALIS E, BELARDO C, DE FELICE R, DI DONATO S, NATALE A, RUSSO M, AA. VV., Gelvi M, Tavoletta C, Pitzalis, E, Belardo, C, DE FELICE, R, DI DONATO, S, Natale, A, and Russo, M
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- 2018
47. I traduttori di fronte alle citazioni coraniche: errori ed estraneità culturale
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Di Donato, S., primary
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- 2006
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48. Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice
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Shankaran, M, Di Paolo, E, Leoni, V, Caccia, C, Ferrari Bardile, C, Mohammed, H, Di Donato, S, Kwak, S, Marchionini, D, Turner, S, Cattaneo, E, Valenza, M, Shankaran M, Di Paolo E, Leoni V, Caccia C, Ferrari Bardile C, Mohammed H, Di Donato S, Kwak S, Marchionini D, Turner S, Cattaneo E, Valenza M, Shankaran, M, Di Paolo, E, Leoni, V, Caccia, C, Ferrari Bardile, C, Mohammed, H, Di Donato, S, Kwak, S, Marchionini, D, Turner, S, Cattaneo, E, Valenza, M, Shankaran M, Di Paolo E, Leoni V, Caccia C, Ferrari Bardile C, Mohammed H, Di Donato S, Kwak S, Marchionini D, Turner S, Cattaneo E, and Valenza M
- Abstract
Cholesterol precursors and cholesterol levels are reduced in brain regions of Huntington's disease (HD) mice. Here we quantified the rate of in vivo de novo cholesterol biosynthesis in the HD brain. Samples from different brain regions and blood of the heterozygous knock-in mouse model carrying 175 CAG repeats (Q175) at different phenotypic stages were processed independently by two research units to quantify cholesterol synthesis rate by 2H2O labeling and measure the concentrations of lathosterol, cholesterol and its brain-specific cholesterol catabolite 24-hydroxy-cholesterol (24OHC) by isotope dilution mass spectrometry. The daily synthesis rate of cholesterol and the corresponding concentration of lathosterol were significantly reduced in the striatum of heterozygous Q175 mice early in the disease course. We also report that the decrease in lathosterol was inversely correlated with CAG-size at symptomatic stage, as observed in striatal samples from an allelic series of HD mice. There was also a significant correlation between the fractional synthesis rates of total cholesterol and 24OHC in brain of wild-type (WT) and Q175 mice, supporting the evidence that plasma 24OHC may reflect cholesterol synthesis in the adult brain. This comprehensive analysis demonstrates consistent cholesterol biosynthesis defects in HD mouse models and suggests that plasma 24OHC may serve as a biomarker of brain cholesterol metabolism.
- Published
- 2017
49. EFNS guidelines on the molecular diagnosis of mitochondrial disorders
- Author
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Finsterer, J., Harbo, H. F., Baets, J., Van Broeckhoven, C., Di Donato, S., Fontaine, B., De Jonghe, P., Lossos, A., Lynch, T., Mariotti, C., Schöls, L., Spinazzola, A., Szolnoki, Z., Tabrizi, S. J., Tallaksen, C. M. E., Zeviani, M., Burgunder, J.-M., and Gasser, T.
- Published
- 2009
- Full Text
- View/download PDF
50. PLASMA 24S-HYDROXYCHOLESTEROL AND CAUDATE MRI IN PREMANIFEST AND EARLY HUNTINGTONʼS DISEASE: C03
- Author
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Leoni, V, Mariotti, C, Tabrizi, S J, Valenza, M, Mandelli, L, Grisoli, M, Cattaneo, E, and Di Donato, S
- Published
- 2009
- Full Text
- View/download PDF
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