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507 results on '"Di Matteo, Berardo"'

9. Society for translational medicine-expert consensus on the treatment of osteoarthritis

Author

Shi, Dongquan, Clement, Nicholas D, Bhonde, Rameah, Ikegawa, Shiro, Mascarenhas, Vasco V, Di Matteo, Berardo, Indelli, Pier Francesco, Kourkoumelis, Nikolaos, Rodríguez-Merchán, E Carlos, Sheykhhasan, Mohsen, Fu, Freddie H, Vaz, Marco Aurélio, Kong, Jian, Azantsa, Boris Gabin Kingue, Ye, Chuan, Halabchi, Farzin, Cornish, Stephen M, Hausmann, Leslie RM, Campos, André Luiz Siqueira, Lopes de Jesus, Carlos César, Jorgensen, Christian, Ilieva, Elena M, Wang, Weiguo, Martínez, Laura Villarreal, Ahn, Hyochol, Shirinsky, Ivan V, Cheung, Corjena, Knutsen, Gunnar, Petersen, Wolf, Lane, Nancy E, Cai, Hong, Xu, Wei, Wu, Jian, Lu, Jun, Zhang, Yingze, and Jiang, Qing

Published
2019

10. Scaffolds for Cartilage Repair

Author

Kon, Elizaveta, Altomare, Daniele, Dorotei, Andrea, Di Matteo, Berardo, Marcacci, Maurilio, Krych, Aaron J., editor, Biant, Leela C., editor, Gomoll, Andreas H., editor, Espregueira-Mendes, João, editor, Gobbi, Alberto, editor, and Nakamura, Norimasa, editor

Published
2021
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13. Limited evidence for the usage of renin–angiotensin–aldosterone pathway blockers to prevent arthrofibrosis after total knee arthroplasty. A systematic review of clinical evidence.

Author

Anzillotti, Giuseppe, Gomoll, Andreas H., Conte, Pietro, Bulgarelli, Alberto, Queirazza, Paolo, Marcacci, Maurilio, Kon, Elizaveta, and Di Matteo, Berardo

Subjects
TRANSFORMING growth factors-beta, TOTAL knee replacement, ANGIOTENSIN-receptor blockers, ACE inhibitors, OPERATIVE surgery
Abstract

Purpose: Despite advances in surgical techniques and rehabilitation protocols, arthrofibrosis following total knee arthroplasty (TKA) still has poor outcomes. In the last decade, attention has been focused on the pathogenesis and cascade of events leading to the development of fibrosis. Currently, one of the most promising approaches consists in the indirect antagonisation of transforming growth factor beta 1 (TGF‐beta 1) through the downregulation of the renin–angiotensin–aldosterone system (RAAS). This systematic review aims to analyse the available evidence regarding the use of angiotensin receptor blockers (ARBs)/angiotensin‐converting‐enzyme inhibitors (ACEi) in order to prevent post‐operative knee arthrofibrosis following TKA. Methods: Extensive research on the PubMed, Cochrane, and Google Scholar databases was performed on 8 July 2024, using keywords related to ARBs, ACE inhibitors and arthrofibrosis. Inclusion criteria included: (1) clinical trials of any level of evidence; (2) written in English; (3) studies conducted on humans; and (4) evaluating the antifibrotic effects of ACE inhibitors or ARBs administered for TKA surgeries. Exclusion criteria were articles written in other languages; preclinical studies; expert opinions; reviews and trials evaluating the effects of ACEi/ARBs not related to their antifibrotic effect after TKA. Results: A total of six studies met the inclusion criteria and were analysed. All studies were retrospective and involved a total of 158,310 patients. Time of administration varied among the studies as well as the dosage, which fell within the range for cardiological use. Four out of six studies focused exclusively on losartan. Three studies reported a clear, significant correlation between the use of ARBs and/or ACEi and a reduced likelihood of developing arthrofibrosis. Conclusions: The RAAS antagonism could have potential for stiffness prevention after TKA. However, given the side effects and the limited evidence available, the use of ACEi/sartans for the sole purpose of avoiding arthrofibrosis after TKA is not currently recommended. Level of Evidence: Level III. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Biological Treatment in Cartilage Injuries

Author

Kon, Elizaveta, Di Matteo, Berardo, Iacono, Francesco, Vandenbulcke, Filippo, Vitale, Nicolò Danilo, Marcacci, Maurilio, Rocha Piedade, Sérgio, editor, Imhoff, Andreas B., editor, Clatworthy, Mark, editor, Cohen, Moises, editor, and Espregueira-Mendes, João, editor

Published
2019
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22. The Trochlear Bisector as a New Landmark for Kinematic Alignment in Total Knee Arthroplasty: A Radiographic Study.

Author

Iacono, Francesco, Bonanzinga, Tommaso, Di Matteo, Berardo, Iacomella, Alberto, Delmedico, Michelangelo, Gambaro, Francesco Manlio, Favaro, Alberto, and Marcacci, Maurilio

Subjects
TOTAL knee replacement, BISECTORS (Geometry), X-ray imaging, OPERATIVE surgery
Abstract

Background: In recent years, there has been considerable interest in prosthetic alignment techniques for total knee arthroplasty (TKA), particularly in the so-called kinematic alignment, which aims to restore the knee's native alignment. However, implementing this technique requires specialized instruments and procedural steps that can be laborious. This study introduces the bisector of the trochlear groove as a reliable landmark for performing the distal femoral cut while maintaining parallelism with the native femoral joint line. Methods: Three orthopedic specialists assessed 110 X-ray images of full-leg, weight-bearing lower limbs obtained from healthy individuals between January 2021 and December 2022. The bisector of the trochlear groove was identified on the X-ray images, and the angle between this bisector and the femoral joint line was measured. The consistency of these measurements across repeated assessments and different examiners was evaluated. Results: The bisector of the trochlear groove was found to be perpendicular to the femoral joint line, with a mean angle of 89.4°. The inter-rater reliability was 68% within ±1.3° from the mean, while the intra-rater reliability was 82% within ±1.5° from the mean. Conclusions: These results suggest that by performing a femoral cut perpendicular to the bisector of the trochlear groove, surgeons can inherently restore the femoral joint line of the native knee in patients where the native joint line is no longer identifiable due to the effect of osteoarthritis. This method may offer a viable and straightforward alternative to the standard surgical technique currently practiced for kinematic alignment in TKA. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Ozone Therapy versus Hyaluronic Acid Injections for Pain Relief in Patients with Knee Osteoarthritis: Preliminary Findings on Molecular and Clinical Outcomes from a Randomized Controlled Trial

Author

Sconza, Cristiano, primary, Di Matteo, Berardo, additional, Queirazza, Paolo, additional, Dina, Arianna, additional, Amenta, Roberta, additional, Respizzi, Stefano, additional, Massazza, Giuseppe, additional, Ammendolia, Antonio, additional, Kon, Elizaveta, additional, and de Sire, Alessandro, additional

Published
2023
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38. Aragonite-Based Scaffold Versus Microfractures and Debridement for the Treatment of Knee Chondral and Osteochondral Lesions: Results of a Multicenter Randomized Controlled Trial

Author

Altschuler, Nir, primary, Zaslav, Kenneth R., additional, Di Matteo, Berardo, additional, Sherman, Seth L., additional, Gomoll, Andreas H., additional, Hacker, Scott A., additional, Verdonk, Peter, additional, Dulic, Oliver, additional, Patrascu, Jenel M., additional, Levy, Andrew S., additional, Robinson, Dror, additional, and Kon, Elizaveta, additional

Published
2023
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