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Your search keyword '"Di Muzio, Jacopo"' showing total 11 results
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11 results on '"Di Muzio, Jacopo"'

1. Prevention and management of radiotherapy-related toxicities in gynecological malignancies. Position paper on behalf of AIRO (Italian Association of Radiotherapy and Clinical Oncology)

Author

Perrucci, Elisabetta, Macchia, Gabriella, Cerrotta, Annamaria, Andrulli, Angela Damiana, Autorino, Rosa, Barcellini, Amelia, Campitelli, Maura, Corrao, Giulia, Costantini, Sara, De Sanctis, Vitaliana, Di Muzio, Jacopo, Epifani, Valeria, Ferrazza, Patrizia, Fodor, Andrei, Garibaldi, Elisabetta, Laliscia, Concetta, Lazzari, Roberta, Magri, Elena, Mariucci, Cristina, Pace, Maria Paola, Pappalardi, Brigida, Pastorino, Alice, Piccolo, Federica, Scoglio, Claudio, Surgo, Alessia, Titone, Francesca, Tortoreto, Francesca, De Felice, Francesca, and Aristei, Cynthia

Published
2024
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2. Definitive chemoradiation in vulvar squamous cell carcinoma: outcome and toxicity from an observational multicenter Italian study on vulvar cancer (OLDLADY 1.1)

Author

Macchia, Gabriella, Lancellotta, Valentina, Ferioli, Martina, Casà, Calogero, Pezzulla, Donato, Pappalardi, Brigida, Laliscia, Concetta, Ippolito, Edy, Di Muzio, Jacopo, Huscher, Alessandra, Tortoreto, Francesca, Boccardi, Mariangela, Lazzari, Roberta, Perrone, Anna Myriam, Raspagliesi, Francesco, Gadducci, Angiolo, Garganese, Giorgia, Fragomeni, Simona Maria, Ferrandina, Gabriella, Morganti, Alessio Giuseppe, Gambacorta, Maria Antonietta, and Tagliaferri, Luca

Published
2024
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3. Observational multicenter Italian study on vulvar cancer adjuvant radiotherapy (OLDLADY 1.2): a cooperation among AIRO Gyn, MITO and MaNGO groups

Author

Macchia, Gabriella, Casà, Calogero, Ferioli, Martina, Lancellotta, Valentina, Pezzulla, Donato, Pappalardi, Brigida, Laliscia, Concetta, Ippolito, Edy, Di Muzio, Jacopo, Huscher, Alessandra, Tortoreto, Francesca, Boccardi, Mariangela, Lazzari, Roberta, De Iaco, Pierandrea, Raspagliesi, Francesco, Gadducci, Angiolo, Garganese, Giorgia, Ferrandina, Gabriella, Morganti, Alessio Giuseppe, and Tagliaferri, Luca

Published
2022
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6. Definitive chemoradiation in vulvar squamous cell carcinoma: outcome and toxicity from an observational multicenter Italian study on vulvar cancer (OLDLADY 1.1)

Author

Macchia, Gabriella, primary, Lancellotta, Valentina, additional, Ferioli, Martina, additional, Casà, Calogero, additional, Pezzulla, Donato, additional, Pappalardi, Brigida, additional, Laliscia, Concetta, additional, Ippolito, Edy, additional, Di Muzio, Jacopo, additional, Huscher, Alessandra, additional, Tortoreto, Francesca, additional, Boccardi, Mariangela, additional, Lazzari, Roberta, additional, Perrone, Anna Myriam, additional, Raspagliesi, Francesco, additional, Gadducci, Angiolo, additional, Garganese, Giorgia, additional, Fragomeni, Simona Maria, additional, Ferrandina, Gabriella, additional, Morganti, Alessio Giuseppe, additional, Gambacorta, Maria Antonietta, additional, and Tagliaferri, Luca, additional

Published
2023
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11. Induction Chemotherapy and Sequential Concomitant Chemo-radiation in Locally Advanced Head and Neck Cancers: How Induction-phase Intensity and Treatment Breaks May Impact on Clinical Outcomes.

Author

Franco P, Potenza I, Schena M, Riva G, Pecorari G, Garzino Demo P, Fasolis M, Moretto F, Garzaro M, Di Muzio J, Melano M, Airoldi M, Ragona R, Rampino M, and Ricardi U

Subjects
Carcinoma, Squamous Cell mortality, Carcinoma, Squamous Cell pathology, Cisplatin administration & dosage, Docetaxel, Female, Fluorouracil administration & dosage, Follow-Up Studies, Head and Neck Neoplasms mortality, Head and Neck Neoplasms pathology, Humans, Induction Chemotherapy, Male, Middle Aged, Neoplasm Grading, Neoplasm Recurrence, Local mortality, Neoplasm Recurrence, Local pathology, Neoplasm Staging, Prognosis, Radiotherapy, Intensity-Modulated, Remission Induction, Retrospective Studies, Survival Rate, Taxoids administration & dosage, Time Factors, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Carcinoma, Squamous Cell therapy, Chemoradiotherapy, Head and Neck Neoplasms therapy, Neoplasm Recurrence, Local therapy
Abstract

Aim: The purpose of the study was to assess outcomes of locally advanced head and neck (LAHNC) treated with induction chemotherapy (ICT) and subsequent concurrent chemo-radiation., Patients and Methods: A total of 71 LAHNC patients were treated with 2-3 cycles of docetaxel, cisplatin and 5-fluorouracil as induction chemotherapy and subsequent concurrent chemoradiation with weekly cisplatin or carboplatin. Definitive radiotherapy was delivered with intensity-modulated radiation and a simultaneous integrated boost approach up to a total dose of 70 Gy in 35 fractions to the macroscopic primary and nodal disease., Results: Actuarial 2-year OS, CSS, DFS, MFS, LC were 55.3% (95%CI=39.3-68.6), 58.6% (95%CI=41.9-72), 60.5% (95%CI=47.3-71.4), 87.3% (95%CI=76.2-93.5) and 74.7% (95%CI=61.5-83.9), respectively. On multivariate analysis undergoing to 3 vs. 2 cycles of TPF (HR=22.31; 95%CI=2.68-185.66; p=0.004) and radiotherapy treatment break >4 days (HR=1.28; 95%CI=1.06-1.55; p=0.01) negatively affected cancer-specific survival (CSS) with statistical significance. Achieving complete remission after ICT had a statistically significant impact on CSS (HR=0.9; 95%CI=0.01-0.54; p=0.009). Patients undergoing ICT with 3 cycles had more frequently treatment breaks compared to those submitted to 2 cycles (HR=1.36; 95%CI=1.06-1.73; p=0.01), and had statistically significant longer treatment break time (5.9+1.8 vs. 3+0.36; p=0.02)., Conclusion: A shorter ICT phase may be a better option enhancing patients' tolerance during concurrent chemoradiation and affecting clinical outcomes., (Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.)

Published
2015

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