354 results on '"Di Stefano, Giuseppina"'
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2. Proteomic profile of BxPC-3 cells after treatment with BRC4
3. Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells.
4. Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells
5. Lactate Can Modulate the Antineoplastic Effects of Doxorubicin and Relieve the Drug’s Oxidative Damage on Cardiomyocytes
6. LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells
7. Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells
8. Balance Rehabilitation through Robot-Assisted Gait Training in Post-Stroke Patients: A Systematic Review and Meta-Analysis
9. An 19f Nmr Fragment-Based Approach for the Discovery and Development of Brca2-Rad51 Inhibitors to Pursuit Synthetic Lethality in Combination with Parp Inhibition in Pancreatic Cancer
10. Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors
11. Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes
12. Lactate is a potential promoter of tamoxifen resistance in MCF7 cells
13. Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme
14. The Report-AGE project: a permanent epidemiological observatory to identify clinical and biological markers of health outcomes in elderly hospitalized patients in Italy
15. The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination
16. Human lactate dehydrogenase A undergoes allosteric transitions under pH conditions inducing the dissociation of the tetrameric enzyme
17. Lactate Upregulates the Expression of DNA Repair Genes, Causing Intrinsic Resistance of Cancer Cells to Cisplatin
18. Lactosaminated human albumin, a hepatotropic carrier of drugs
19. Characterisation of the conjugate of the (6-maleimidocaproyl)hydrazone derivative of doxorubicin with lactosaminated human albumin by 13C NMR spectroscopy
20. Effects of robot-assisted gait training on postural instability in Parkinson's disease: a systematic review
21. Brain aging: The zinc connection
22. Doxorubicin coupled to lactosaminated albumin: Effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats
23. Doxorubicin coupled to lactosaminated human albumin: a hepatocellular carcinoma targeted drug
24. Peripheral inflammatory biomarkers of Alzheimer’s disease: the role of platelets
25. Inhibition of lactate dehydrogenase activity as an approach to cancer therapy
26. RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer
27. Transhepatic intraluminal brachytherapy combined with biliary stenting in the treatment of unresectable malignant biliary obstruction
28. Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment
29. Altered glycosylation profile of purified plasma ACT from Alzheimer’s disease
30. Aging-like alterations of SDH activity in Purkinje cell mitochondria of adult vitamin-E deficient rats
31. Dietary restriction modulates synaptic structural dynamics in the aging hippocampus
32. Effect of sorafenib on the energy metabolism of hepatocellular carcinoma cells
33. Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors
34. Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib
35. Contributors
36. Neurobiology of the Aging Brain
37. Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine
38. A Ketogenic Diet Increases Succinic Dehydrogenase Activity in Aging Cardiomyocytes
39. Neuronal Apoptosis in Alzheimerʼs Disease
40. Comment on “Expression of amyloid beta peptide in human platelets: Pivotal role of the phospholipase Cγ2-protein kinase C pathway in platelet activation” by Shen et al.
41. Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin
42. Synaptic and Mitochondrial Morphometry Provides Structural Correlates of Successful Brain Aging
43. Alterations of Synaptic Turnover Rate in Aging May Trigger Senile Plaque Formation and Neurodegeneration
44. Release of β-Amyloid from High-Density Platelets: Implications for Alzheimerʼs Disease Pathology
45. Preservation of Mitochondrial Volume Homeostasis at the Early Stages of Age-Related Synaptic Deterioration
46. Experimental Apoptosis Provides Clues about the Role of Mitochondrial Changes in Neuronal Death
47. Reactive Structural Dynamics of Synaptic Mitochondria in Ischemic Delayed Neuronal Death
48. A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade
49. Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors
50. Liver-targeted doxorubicin: effects on rat regenerating hepatocytes
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