21 results on '"Di Vetta V"'
Search Results
2. Impact of Preoperative Teaching on Surgical Option of Patients Qualifying for Bariatric Surgery
- Author
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Giusti, V, De Lucia, A, Di Vetta, V, Calmes, J M, Héraïef, E, Gaillard, R C, Burckhardt, P, and Suter, M
- Published
- 2004
- Full Text
- View/download PDF
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3. A non- invasive assessment of hepatic glycogen kinetics and post- absorptive gluconeogenesis in man
- Author
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Gay, L. J., Schneiter, Ph, Schutz, Y., Di Vetta, V., Jequier, E., and Tappy, L.
- Published
- 1994
- Full Text
- View/download PDF
4. Effect of physical exercise on glycogen turnover and net substrate utilization according to the nutritional state
- Author
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Schneiter, P., Di Vetta, V., Jequier, E., and Tappy, L.
- Subjects
Exercise -- Physiological aspects ,Glycogen metabolism -- Physiological aspects ,Fat metabolism -- Research ,Biological sciences - Abstract
A study was conducted to determine the effect on glycogen turnover and fat oxidation of physical exercise performed after a meal or in a fasting state. One group of healthy subjects exercised 90 min. after eating a standard breakfast, while another group exercised after an overnight fast and ate a standard breakfast 30 min. after exercising. The results showed that physical exercise in a fasting state stimulated faster glycogen turnover and promoted fat oxidation better than physical exercise performed after a meal. more...
- Published
- 1995
5. Nutrition – Obésité
- Author
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Giusti, V., primary, Clarisse, M., additional, and Di Vetta, V., additional
- Published
- 2005
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6. Ad libitum intake of a high-carbohydrate or high-fat diet in young men: effects on nutrient balances
- Author
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Proserpi, C, primary, Sparti, A, additional, Schutz, Y, additional, Di Vetta, V, additional, Milon, H, additional, and Jéquier, E, additional
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- 1997
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- View/download PDF
7. [Liraglutide in the treatment of obesity : a multidisciplinary approach].
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Nest S, Gilet P, Di Vetta V, Dudin F, Frantz J, and Favre L
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- Humans, Liraglutide therapeutic use, Obesity drug therapy, Weight Loss, Anti-Obesity Agents therapeutic use, Diabetes Mellitus, Type 2 drug therapy
- Abstract
Liraglutide, which has been prescribed for several years for the treatment of type 2 diabetes, is now proposed for the management of patients with BMI between 28 and 35 kg/m
2ipt> in the presence of metabolic comorbidity or BMI ≥ 35 kg/m 2 . Its reimbursement by the health insurance is conditioned on weight loss results and time limited. Careful preparation of the patient and his commitment to lifestyle changes are essential for the success and good tolerance of the treatment. The introduction of this treatment requires a multidisciplinary follow-up to ensure optimal results. The place of liraglutide in the pharmacopeia of obesity, a chronic disease that requires long-term treatment, should be clarified., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article. more...- Published
- 2022
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8. [Multidisciplinary management of dumping syndromes after bariatric surgery].
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Di Vetta V, Heller A, Pralong F, and Favre L
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- Bariatric Surgery methods, Cooperative Behavior, Dumping Syndrome etiology, Humans, Hypoglycemia etiology, Interdisciplinary Communication, Quality of Life, Bariatric Surgery adverse effects, Dumping Syndrome therapy, Postoperative Complications therapy
- Abstract
Dumping syndromes are a frequent complication of gastric or bariatric surgery and include early and late dumping. Early dumping is a consequence of rapid delivery of hyperosmolar nutrients into the bowel. Late dumping is the result of a reactive hypoglycemia induced by a hyperinsulinemic response. These syndromes are becoming increasingly prevalent with the rising incidence of bariatric surgery. Effective management of these complications requires multidisciplinary collaboration. First line management of early and late dumping syndrome involves specific dietary and behavioral modifications which generally improve the quality of life of patients., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article. more...
- Published
- 2017
9. Energy and macronutrient intake after gastric bypass for morbid obesity: a 3-y observational study focused on protein consumption.
- Author
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Giusti V, Theytaz F, Di Vetta V, Clarisse M, Suter M, and Tappy L
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- Adult, Basal Metabolism, Diet, Female, Humans, Prospective Studies, Dietary Carbohydrates administration & dosage, Dietary Fats administration & dosage, Dietary Proteins administration & dosage, Energy Intake, Gastric Bypass adverse effects, Obesity, Morbid surgery
- Abstract
Background: The effect of a Roux-en-Y gastric bypass (RYGB) on body weight has been amply documented, but few studies have simultaneously assessed the evolution of energy and macronutrient intakes, energy expenditure, and changes in body composition over time after an RYGB., Objective: We evaluated energy and macronutrient intakes, body composition, and the basal metabolic rate (BMR) in obese female patients during the initial 3 y after an RYGB., Methods: Sixteen women with a mean ± SEM body mass index (in kg/m(2)) of 44.1 ± 1.6 were included in this prospective observational study. The women were studied on 6 different occasions as follows: before and 1, 3, 6, 12 (n = 16), and 36 (n = 8) mo after surgery. On each occasion, food intake was evaluated from 4- or 7-d dietary records, body composition was assessed with the use of bio-impedancemetry, and energy expenditure was measured with the use of indirect calorimetry., Results: Body weight evolution showed the typical pattern reported after an RYGB. Total energy intake was 2072 ± 108 kcal/d at baseline and decreased to 681 ± 58 kcal/d at 1 mo after surgery (P < 0.05 compared with at baseline). Total energy intake progressively increased to reach 1240 ± 87 kcal/d at 12 mo after surgery (P < 0.05 compared with at 1 mo after surgery) and 1448 ± 57 kcal/d at 36 mo after surgery (P < 0.05 compared with at 12 mo after surgery). Protein intake was 87 ± 4 g/d at baseline and ± 2 g/d 1 mo after surgery (P < 0.05 compared with at baseline) and increased progressively thereafter to reach 57 ± 3 g/d at 36 mo after surgery (P < 0.05 compared with at 1 mo after surgery). Carbohydrate and fat intakes over time showed similar patterns. Protein intake from meat and cheese were significantly reduced early at 1 mo after surgery but increased thereafter (P < 0.05). The BMR decreased from 1.12 ± 0.04 kcal/min at baseline to 0.93 ± 0.03, 0.86 ± 0.03, and 0.85 ± 0.04 kcal/min at 3, 12, and 36 mo after surgery, respectively (all P < 0.05 compared with at baseline)., Conclusions: Total energy, carbohydrate, fat, and protein intakes decreased markedly during the initial 1-3 mo after an RYGB, whereas the BMR moderately decreased. The reduction in protein intake was particularly severe at 1 mo after surgery, and protein intake increased gradually after 3-6 mo after surgery. This trial was registered at clinicaltrials.gov as NCT01891591., (© 2016 American Society for Nutrition.) more...
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- 2016
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10. [How to facilitate protein consumption after gastric bypass?].
- Author
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Clarisse M, Di Vetta V, Siegrist C, and Giusti V
- Subjects
- Diet, Feeding Behavior psychology, Humans, Patient Education as Topic methods, Dietary Proteins administration & dosage, Gastric Bypass methods, Obesity surgery
- Abstract
After a gastric bypass, covering protein needs is impossible. This deficit is co-responsible for several postoperative complications so it is essential to inform, prepare and train every patient candidate for such an intervention. To increase protein intake, it is important to work on two different aspects: on the one hand on food sources, targeting the richest food and, on the other hand, on food tolerance so that these foods can be consumed. In fact, gastric bypass induces not only a reduction in gastric volume, but also reduces the passage from the stomach to the intestine. Changes in feeding behavior are much needed to improve food tolerance. more...
- Published
- 2013
11. [When the obese patient can't lose any weight or keeps putting some on].
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Di Vetta V, Szymanski J, Clarisse M, and Giusti V
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- Compulsive Behavior psychology, Emotions, Feeding and Eating Disorders psychology, Humans, Obesity psychology, Weight Gain, Weight Loss, Feeding Behavior psychology, Obesity therapy, Patient Education as Topic methods
- Abstract
The traditional obesity treatments have proven to be ineffective in the long-term. The presence of eating disorders frequently explains this phenomena. Eating educational and behavioral aspects must be addressed in a practical way so that patients could gradually become aware of their behavior towards food as well as internal sensations associated with hunger, satiety, craving and pleasure. Finally, the link between emotions and compulsive eating behaviors during and between meals is an essential aspect that the general practitioner can help the patient to understand. A specialized psychological treatment can then be considered when the patient shows sufficient motivation and consciousness. more...
- Published
- 2012
12. [Sweeteners: between myth and reality].
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Clarisse M, Di Vetta V, and Giusti V
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- Adult, Age Factors, Child, Child, Preschool, Diabetes Mellitus diet therapy, Diarrhea chemically induced, Energy Intake, Female, Humans, Obesity diet therapy, Overweight, Pregnancy, Time Factors, Weight Loss, Sweetening Agents administration & dosage, Sweetening Agents adverse effects
- Abstract
As the prevalence of obesity and diabetes are continually increasing, the use of "false sugars" otherwise known as sweeteners, and their associated health issues are being more and more discussed. A higher sugared power, less calories as well as a moderated or non-existent effect on blood sugar would lead to believe that sweeteners are helpful. However, we CANNOT say that they are THE solution as they can contain calories, may have some undesired effects, and moreover they ease the conscience without actually allowing a weight loss with their sole use. They are to be used with judgment, wittingly and especially when comparing sweetened products. The sweetener myth is often far from reality. It is therefore important to give our patients the means to analyze their dietary intake with regard to their sweeteners ingestion. more...
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- 2009
13. [Gastric bypass: management of complications and food tolerance].
- Author
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Di Vetta V, Kraytem A, and Giusti V
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- Humans, Patient Education as Topic, Postoperative Care, Eating, Gastric Bypass adverse effects
- Abstract
Bariatric surgery is the only treatment inducing effective weight loss on the long term. The success of such an intervention is possible by carefully selecting and educating the candidates. Good understanding of the bariatric surgery implications allows the patients to modify their eating habits and thus decrease complications and food intolerance. Therefore patient education requires a multidisciplinary approach which implies the follow-up of a dietician on the long term. Mastication, speed of food ingestion, avoidance of carbonated beverages as well as the obligation to drink at frequent and regular intervals are the most difficult aspects to be taught to the patients. more...
- Published
- 2008
14. [Hypocaloric diets: which ones to advise/avoid?].
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Di Vetta V, Clarisse M, and Giusti V
- Subjects
- Humans, Patient Compliance, Weight Loss, Diet Fads, Diet, Reducing, Energy Intake, Obesity diet therapy
- Abstract
A hypocaloric diet, whatever the proposed type, is an inadapted treatment to chronic disease, like obesity. All diets are inefficient on the long term. The weight loss is generally small, about 1-2 kg a year. The results are the same, independently of the type of diet, and the patient's compliance is clearly the main key to succeed. About 80% of patients regain weight the first month following the diet, and only 1% can keep the obtained weight a year later. Nearly half of the patients involved in a diet program give up before the end. Finally, because of risks of macro and micro nutriments deficiency, certain diets are to be avoided and hypocaloric diet shouldn't be proposed. more...
- Published
- 2005
15. Effect of carbohydrate overfeeding on whole body and adipose tissue metabolism in humans.
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Minehira K, Bettschart V, Vidal H, Vega N, Di Vetta V, Rey V, Schneiter P, and Tappy L
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- Adipose Tissue growth & development, Adult, Basal Metabolism physiology, Calorimetry, Indirect, Dietary Carbohydrates administration & dosage, Fatty Acids, Volatile blood, Female, Humans, Lipids blood, Male, Obesity etiology, Obesity metabolism, Oxygen Consumption, RNA, Messenger metabolism, Triglycerides biosynthesis, Triglycerides blood, Adipose Tissue metabolism, Dietary Carbohydrates metabolism, Energy Metabolism physiology, Lipids biosynthesis
- Abstract
Objective: To evaluate the effect of a 4-day carbohydrate overfeeding on whole body net de novo lipogenesis and on markers of de novo lipogenesis in subcutaneous adipose tissue of healthy lean humans., Research Methods and Procedures: Nine healthy lean volunteers (five men and four women) were studied after 4 days of either isocaloric feeding or carbohydrate overfeeding. On each occasion, they underwent a metabolic study during which their energy expenditure and net substrate oxidation rates (indirect calorimetry), and the fractional activity of the pentose-phosphate pathway in subcutaneous adipose tissue (subcutaneous microdialysis with 1,6(13)C2,6,6(2)H2 glucose) were assessed before and after administration of glucose. Adipose tissue biopsies were obtained at the end of the experiments to monitor mRNAs of key lipogenic enzymes., Results: Carbohydrate overfeeding increased basal and postglucose energy expenditure and net carbohydrate oxidation. Whole body net de novo lipogenesis after glucose loading was markedly increased at the expense of glycogen synthesis. Carbohydrate overfeeding also increased mRNA levels for the key lipogenic enzymes sterol regulatory element-binding protein-1c, acetyl-CoA carboxylase, and fatty acid synthase. The fractional activity of adipose tissue pentose-phosphate pathway was 17% to 22% and was not altered by carbohydrate overfeeding., Discussion: Carbohydrate overfeeding markedly increased net de novo lipogenesis at the expense of glycogen synthesis. An increase in mRNAs coding for key lipogenic enzymes suggests that de novo lipogenesis occurred, at least in part, in adipose tissue. The pentose-phosphate pathway is active in adipose tissue of healthy humans, consistent with an active role of this tissue in de novo lipogenesis. more...
- Published
- 2003
- Full Text
- View/download PDF
16. [Preparation and follow up of candidates for surgical treatment of obesity: pre- and postoperative courses].
- Author
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Giusti V, Di Vetta V, Suter M, Héraïef E, Gaillard RC, and Burckhardt P
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- Follow-Up Studies, Humans, Postoperative Care, Preoperative Care, Obesity, Morbid surgery, Patient Education as Topic
- Published
- 2002
17. Effect of diets high or low in unavailable and slowly digestible carbohydrates on the pattern of 24-h substrate oxidation and feelings of hunger in humans.
- Author
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Sparti A, Milon H, Di Vetta V, Schneiter P, Tappy L, Jéquier E, and Schutz Y
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- Adult, Analysis of Variance, Biological Availability, Body Composition, Calorimetry, Dietary Carbohydrates administration & dosage, Dietary Carbohydrates pharmacokinetics, Digestion, Female, Humans, Male, Oxidation-Reduction, Pain Measurement, Postprandial Period, Substrate Specificity, Diet, Dietary Carbohydrates metabolism, Energy Metabolism, Hunger
- Abstract
Background: The pattern of substrate utilization with diets containing a high or a low proportion of unavailable and slowly digestible carbohydrates may constitute an important factor in the control, time course, and onset of hunger in humans., Objective: We tested the hypothesis that isoenergetic diets differing only in their content of unavailable carbohydrates would result in different time courses of total, endogenous, and exogenous carbohydrate oxidation rates., Design: Two diets with either a high (H diet) or a low (L diet) content of unavailable carbohydrates were fed to 14 healthy subjects studied during two 24-h periods in a metabolic chamber. Substrate utilization was assessed by whole-body indirect calorimetry. In a subgroup of 8 subjects, endogenous and exogenous carbohydrate oxidation were assessed by prelabeling the body glycogen stores with [(13)C]carbohydrate. Subjective feelings of hunger were estimated with use of visual analogue scales., Results: Total energy expenditure and substrate oxidation did not differ significantly between the 2 diets. However, there was a significant effect of diet (P: = 0.03) on the carbohydrate oxidation pattern: the H diet elicited a lower and delayed rise of postprandial carbohydrate oxidation and was associated with lower hunger feelings than was the L diet. The differences in hunger scores between the 2 diets were significantly associated with the differences in the pattern of carbohydrate oxidation among diets (r = -0.67, P: = 0. 006). Exogenous and endogenous carbohydrate oxidation were not significantly influenced by diet., Conclusions: The pattern of carbohydrate utilization is involved in the modulation of hunger feelings. The greater suppression of hunger after the H diet than after the L diet may be helpful, at least over the short term, in individuals attempting to better control their food intake. more...
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- 2000
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18. Effects of short-term carbohydrate or fat overfeeding on energy expenditure and plasma leptin concentrations in healthy female subjects.
- Author
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Dirlewanger M, di Vetta V, Guenat E, Battilana P, Seematter G, Schneiter P, Jéquier E, and Tappy L
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- 3-Hydroxybutyric Acid blood, Adipose Tissue chemistry, Adult, Basal Metabolism, Calorimetry, Indirect, Exercise, Extracellular Space chemistry, Fatty Acids, Nonesterified blood, Female, Glucose analysis, Humans, Lactates analysis, Microdialysis, Time Factors, Dietary Carbohydrates administration & dosage, Dietary Fats administration & dosage, Eating, Energy Metabolism physiology, Leptin blood
- Abstract
Objective: To determine the effects of excess carbohydrate or fat intake on plasma leptin concentrations and energy expenditure., Design: Ten healthy lean females were studied: (a) during a 3 day isoenergetic diet (ISO); (b) during 3 day carbohydrate overfeeding (CHO OF); and (c) during 3 day fat overfeeding (FAT OF). During each test, basal metabolic rate, the energy expended during mild physical activity and recovery, and 24 h energy expenditure (24 h EE) were measured with indirect calorimetry. The concentrations of glucose and lactate were monitored in subcutaneous interstitial fluid over a 24 h period using microdialysis. Plasma hormone and substrate concentrations were measured in a blood sample collected in the morning of the fourth day., Results: CHO OF increased plasma leptin concentrations by 28%, and 24 h EE by 7%. Basal metabolic rate and the energy expended during physical activity were not affected. FAT OF did not significantly change plasma leptin concentrations or energy expenditure. There was no relationship between changes in leptin concentrations and changes in energy expenditure, suggesting that leptin is not involved in the stimulation of energy metabolism during overfeeding. Interstitial subcutaneous glucose and lactate concentrations were not altered by CHO OF and FAT OF., Conclusions: CHO OF, but not FAT OF, increases energy expenditure and leptin concentration. more...
- Published
- 2000
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19. Effect of moderate physical activity on plasma leptin concentration in humans.
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Dirlewanger M, Di Vetta V, Giusti V, Schneiter P, Jéquier E, and Tappy L
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- 3-Hydroxybutyric Acid blood, Adult, Energy Metabolism physiology, Fatty Acids, Nonesterified blood, Female, Humans, Leptin, Male, Osmolar Concentration, Physical Exertion physiology, Proteins analysis
- Abstract
In subjects who maintain a constant body mass, the increased energy expenditure induced by exercise must be compensated by a similar increase in energy intake. Since leptin has been shown to decrease food intake in animals, it can be expected that physical exercise would increase energy intake by lowering plasma leptin concentrations. This effect may be secondary either to exercise-induced negative energy balance or to other effects of exercise. To delineate the effects of moderate physical activity on plasma leptin concentrations, 11 healthy lean subjects (4 men, 7 women) were studied on three occasions over 3 days; in study 1 they consumed an isoenergetic diet (1.3 times resting energy expenditure) over 3 days with no physical activity; in study 2 the subjects received the same diet as in study 1, but they exercised twice daily during the 3 days (cycling at 60 W for 30 min); in study 3 the subjects exercised twice daily during the 3 days, and their energy intake was increased by 18% to cover the extra energy expenditure induced by the physical activity. Fasting plasma leptin concentration (measured on the morning of day 4) was unaltered by exercise [8.64 (SEM 2.22) 7.17 (SEM 1.66), 7.33 (SEM 1.72) 1 microg x l(-1) in studies 1, 2 and 3, respectively]. It was concluded that a moderate physical activity performed over a 3-day period does not alter plasma leptin concentrations, even when energy balance is slightly negative. This argues against a direct effect of physical exercise on plasma leptin concentrations, when body composition is unaltered. more...
- Published
- 1999
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20. Compliance to dietary advice directed towards increasing the carbohydrate to fat ratio of the everyday diet.
- Author
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Lyon XH, Di Vetta V, Milon H, Jéquier E, and Schutz Y
- Subjects
- Adult, Basal Metabolism physiology, Body Composition physiology, Body Weight physiology, Calorimetry, Indirect, Carbon Radioisotopes, Eating physiology, Energy Metabolism physiology, Female, Glucose metabolism, Humans, Middle Aged, Obesity physiopathology, Obesity psychology, Surveys and Questionnaires, Diet, Reducing standards, Dietary Carbohydrates administration & dosage, Dietary Fats administration & dosage, Obesity diet therapy, Patient Compliance
- Abstract
Objective: To assess the effects, on food intake, body weight and body composition, of compliance to advice aiming at increasing the carbohydrate to fat ratio of the everyday diet without imposing voluntary restriction on the amount of food consumed., Design: Eight moderately overweight women (body mass index > 27 kg/m2, relative body fat mass > 30%) received dietary advice during a 2 month period. Additionally, each evening the subjects had to consume a meal artificially enriched with 13C-glucose in order to assess their compliance from the 13CO2 enrichment in expired air., Measurements: Dietary intakes, body weight, body composition and individual compliance., Results: The energy derived from fat decreased from 44 +/- 1% to 31 +/- 1% and the proportion of carbohydrate increased from 38 +/- 2% to 50 +/- 1%, whereas the absolute carbohydrate intake remained constant (182 +/- 18 g/d). Energy intake decreased by 1569 +/- 520 kJ/d. There was a net loss of fat mass (1.7 +/- 0.7 kg, P = 0.016) with fat free mass maintenance. Dietary compliance ranged from 20 to 93% (mean: 60 +/- 8%) and was positively correlated to the loss of body fat mass., Conclusion: Advice aiming at increasing diet's carbohydrate to fat ratio induces a loss of fat mass with fat-free mass maintenance. more...
- Published
- 1995
21. Noninvasive assessment of in vivo glycogen kinetics in humans: effect of increased physical activity on glycogen breakdown and synthesis.
- Author
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Schneiter P, Pasche O, Di Vetta V, Jéquier E, and Tappy L
- Subjects
- Adult, Bicarbonates metabolism, Calorimetry, Indirect, Carbon Dioxide metabolism, Carbon Radioisotopes, Female, Glycogen biosynthesis, Humans, Kinetics, Male, Exercise physiology, Glycogen metabolism, Muscle, Skeletal metabolism
- Abstract
In vivo glycogen kinetics was estimated with the simultaneous use of indirect calorimetry and tracer technology in healthy humans during 24-h periods with low or moderate physical activity (1 or 3 exercise sessions each day). Two 13C-carbohydrates meals were administered at 9.30 a.m. and 1.30 p.m., and one 12C-carbohydrates meal at 6.30 p.m. Net carbohydrate oxidation (net CHO ox) was measured over a 24 h period by indirect calorimetry and oxidation of 13C-labelled carbohydrates (13C CHO ox) was estimated from 13CO2 production. Glycogen breakdown, assessed for the period 8.15 a.m.-6.30 p.m. as the difference between net CHO ox and 13C CHO ox, was increased 1.6 times with three exercise sessions [123.3 (SEM 8.0) g] versus one session [77.9 (SEM 7.7) g, P < 0.0001]. Carbohydrate balances over 24 h were close to zero under both conditions, indicating that glycogen breakdown was matched by an equivalent glycogen synthesis. It was concluded that simultaneous use of indirect calorimetry and tracer technology may make possible the estimation of glycogen kinetics in humans. Moderate physical activity enhanced both glycogen breakdown and synthesis. This stimulation of glycogen metabolism may therefore play a role in the enhanced insulin sensitivity induced by physical exercise. more...
- Published
- 1994
- Full Text
- View/download PDF
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