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7. Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

Author

Nguyen, Bastien, Fong, Christopher, Luthra, Anisha, Smith, Shaleigh A., DiNatale, Renzo G., Nandakumar, Subhiksha, Walch, Henry, Chatila, Walid K., Madupuri, Ramyasree, Kundra, Ritika, Bielski, Craig M., Mastrogiacomo, Brooke, Donoghue, Mark T.A., Boire, Adrienne, Chandarlapaty, Sarat, Ganesh, Karuna, Harding, James J., Iacobuzio-Donahue, Christine A., Razavi, Pedram, Reznik, Ed, Rudin, Charles M., Zamarin, Dmitriy, Abida, Wassim, Abou-Alfa, Ghassan K., Aghajanian, Carol, Cercek, Andrea, Chi, Ping, Feldman, Darren, Ho, Alan L., Iyer, Gopakumar, Janjigian, Yelena Y., Morris, Michael, Motzer, Robert J., O’Reilly, Eileen M., Postow, Michael A., Raj, Nitya P., Riely, Gregory J., Robson, Mark E., Rosenberg, Jonathan E., Safonov, Anton, Shoushtari, Alexander N., Tap, William, Teo, Min Yuen, Varghese, Anna M., Voss, Martin, Yaeger, Rona, Zauderer, Marjorie G., Abu-Rustum, Nadeem, Garcia-Aguilar, Julio, Bochner, Bernard, Hakimi, Abraham, Jarnagin, William R., Jones, David R., Molena, Daniela, Morris, Luc, Rios-Doria, Eric, Russo, Paul, Singer, Samuel, Strong, Vivian E., Chakravarty, Debyani, Ellenson, Lora H., Gopalan, Anuradha, Reis-Filho, Jorge S., Weigelt, Britta, Ladanyi, Marc, Gonen, Mithat, Shah, Sohrab P., Massague, Joan, Gao, Jianjiong, Zehir, Ahmet, Berger, Michael F., Solit, David B., Bakhoum, Samuel F., Sanchez-Vega, Francisco, and Schultz, Nikolaus

Published
2022
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8. Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape

Author

Golkaram, Mahdi, Kuo, Fengshen, Gupta, Sounak, Carlo, Maria I., Salmans, Michael L., Vijayaraghavan, Raakhee, Tang, Cerise, Makarov, Vlad, Rappold, Phillip, Blum, Kyle A., Zhao, Chen, Mehio, Rami, Zhang, Shile, Godsey, Jim, Pawlowski, Traci, DiNatale, Renzo G., Morris, Luc G. T., Durack, Jeremy, Russo, Paul, Kotecha, Ritesh R., Coleman, Jonathan, Chen, Ying-Bei, Reuter, Victor E., Motzer, Robert J., Voss, Martin H., Liu, Li, Reznik, Ed, Chan, Timothy A., and Hakimi, A. Ari

Published
2022
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9. Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy

Author

Krishna, Chirag, DiNatale, Renzo G., Kuo, Fengshen, Srivastava, Raghvendra M., Vuong, Lynda, Chowell, Diego, Gupta, Sounak, Vanderbilt, Chad, Purohit, Tanaya A., Liu, Ming, Kansler, Emily, Nixon, Briana G., Chen, Ying-Bei, Makarov, Vladimir, Blum, Kyle A., Attalla, Kyrollis, Weng, Stanley, Salmans, Michael L., Golkaram, Mahdi, Liu, Li, Zhang, Shile, Vijayaraghavan, Raakhee, Pawlowski, Traci, Reuter, Victor, Carlo, Maria I., Voss, Martin H., Coleman, Jonathan, Russo, Paul, Motzer, Robert J., Li, Ming O., Leslie, Christina S., Chan, Timothy A., and Hakimi, A. Ari

Published
2021
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13. The Association Between Small Primary Tumor Size and Prognosis in Metastatic Renal Cell Carcinoma: Insights from Two Independent Cohorts of Patients Who Underwent Cytoreductive Nephrectomy

Author

DiNatale, Renzo G., Xie, Wanling, Becerra, Maria F., Silagy, Andrew W., Attalla, Kyrollis, Sanchez, Alejandro, Mano, Roy, Marcon, Julian, Blum, Kyle A., Benfante, Nicole E., Voss, Martin H., Motzer, Robert J., Coleman, Jonathan, Choueiri, Toni K., Reznik, Ed, Russo, Paul, Heng, Daniel Y.C., and Hakimi, A. Ari

Published
2020
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18. Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma

Author

Becerra, Maria F., Reznik, Ed, Redzematovic, Almedina, Tennenbaum, Daniel M., Kashan, Mahyar, Ghanaat, Mazyar, Casuscelli, Jozefina, Manley, Brandon, Jonsson, Philip, DiNatale, Renzo G., Blum, Kyle A., Durack, Jeremy C., Solomon, Stephen B., Arcila, Maria E., Bourque, Caitlin, Socci, Nick, Carlo, Maria I., Lee, Chung-Han, Voss, Martin H., Feldman, Darren R., Motzer, Robert J., Coleman, Jonathan A., Russo, Paul, Cheng, Emily H., Hakimi, A. Ari, and Hsieh, James J.

Published
2018
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21. Somatic mutations as preoperative predictors of metastases in patients with localized clear cell renal cell carcinoma – An exploratory analysis

Author

Mano, Roy, Duzgol, Cihan, Ganat, Maz, Goldman, Debra A., Blum, Kyle A., Silagy, Andrew W., Walasek, Aleksandra, Sanchez, Alejandro, DiNatale, Renzo G., Marcon, Julian, Kashan, Mahyar, Becerra, Maria F., Benfante, Nicole E., Coleman, Jonathan A., Kattan, Michael W., Russo, Paul, Akin, Oguz, Ostrovnaya, Irina, and Hakimi, A. Ari

Published
2021
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22. Localized Non‐Metastatic Sarcomatoid Renal Cell Carcinoma: A 31 Year Externally Verified Study

Author

Blum, Kyle A., primary, Silagy, Andrew W., additional, Knezevic, Andrea, additional, Weng, Stanley, additional, Wang, Alan, additional, Mano, Roy, additional, Marcon, Julian, additional, DiNatale, Renzo G., additional, Sanchez, Alejandro, additional, Tickoo, Satish, additional, Gupta, Sounak, additional, Motzer, Robert, additional, Haas, Naomi B., additional, Kim, Se Eun, additional, Uzzo, Robert G., additional, Coleman, Jonathan A., additional, Hakimi, A. Ari, additional, and Russo, Paul, additional

Published
2023
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23. Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers

Author

Malouf, Gabriel G., Flippot, Ronan, Dong, Yiyu, Dinatale, Renzo G., Chen, Ying-Bei, Su, Xiaoping, Compérat, Eva, Rouprêt, Morgan, Mano, Roy, Blum, Kyle A., Yao, Hui, Mouawad, Roger, Spano, Jean-Philippe, Khayat, David, Karam, Jose A., Ho, Thai H., Tickoo, Satish K., Russo, Paul, Hsieh, James J., Tannir, Nizar M., and Hakimi, Abraham A.

Published
2020
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24. Preoperative nomogram predicting 12-year probability of metastatic renal cancer – evaluation in a contemporary cohort

Author

Mano, Roy, Duzgol, Cihan, Ganat, Maz, Goldman, Debra A., Blum, Kyle A., Silagy, Andrew W., Walasek, Aleksandra, Sanchez, Alejandro, DiNatale, Renzo G., Marcon, Julian, Kashan, Mahyar, Becerra, Maria F., Benfante, Nicole, Coleman, Jonathan A., Kattan, Michael W., Russo, Paul, Akin, Oguz, Ostrovnaya, Irina, and Hakimi, A. Ari

Published
2020
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25. Localised non‐metastatic sarcomatoid renal cell carcinoma: a 31‐year externally verified study.

Author

Blum, Kyle A., Silagy, Andrew W., Knezevic, Andrea, Weng, Stanley, Wang, Alan, Mano, Roy, Marcon, Julian, DiNatale, Renzo G., Sanchez, Alejandro, Tickoo, Satish, Gupta, Sounak, Motzer, Robert, Haas, Naomi B., Kim, Se Eun, Uzzo, Robert G., Coleman, Jonathan A., Hakimi, A. Ari, and Russo, Paul

Subjects
RENAL cell carcinoma, NEPHRECTOMY, MINIMALLY invasive procedures, CHI-squared test, TUMOR classification, OVERALL survival
Abstract

Objective: To evaluate post‐nephrectomy outcomes and predictors of cancer‐specific survival (CSS) between patients with localised sarcomatoid renal cell carcinoma (sRCC) and those with Grade 4 RCC (non‐sRCC), as most sRCC research focuses on advanced or metastatic disease with limited studies analysing outcomes of patients with localised non‐metastatic sRCC. Patients and Methods: A total of 564 patients with localised RCC underwent partial or radical nephrectomy between June 1988 to March 2019 for sRCC (n = 204) or World Health Organization/International Society of Urological Pathology Grade 4 non‐sRCC (n = 360). The CSS at every stage between groups was assessed. Phase III ASSURE clinical trial data were used to externally validate the CSS findings. The Mann–Whitney U‐test and chi‐squared test compared outcomes and the Kaplan–Meier method evaluated CSS, overall survival (OS) and recurrence‐free survival. Clinicopathological features associated with RCC death were evaluated using Cox proportional hazards regression. Results: The median follow‐up was 31.5 months. The median OS and CSS between the sRCC and Grade 4 non‐sRCC groups was 45 vs 102 months and 49 vs 152 months, respectively (P < 0.001). At every stage, sRCC had worse CSS compared to Grade 4 non‐sRCC. Notably, pT1 sRCC had worse CSS than pT3 Grade 4 non‐sRCC. Negative predictors of CSS were sarcomatoid features, non‐clear cell histology, positive margins, higher stage (pT3/pT4), and use of minimally invasive surgery (MIS). ASSURE external verification showed worse CSS in patients with sRCC (hazard ratio [HR] 1.63, 95% confidence interval [CI] 1.12–2.36; P = 0.01), but not worse outcomes in MIS surgery (HR 1.39, 95% CI 0.75–2.56; P = 0.30). Conclusions: Localised sRCC had worse CSS compared to Grade 4 non‐sRCC at every stage. Negative survival predictors included positive margins, higher pathological stage, use of MIS, and non‐clear cell histology. sRCC is an aggressive variant even at low stages requiring vigilant surveillance and possible inclusion in adjuvant therapy trials. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Supplementary Table from A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma

Author

Rappold, Phillip M., primary, Vuong, Lynda, primary, Leibold, Josef, primary, Chakiryan, Nicholas H., primary, Curry, Michael, primary, Kuo, Fengshen, primary, Sabio, Erich, primary, Jiang, Hui, primary, Nixon, Briana G., primary, Liu, Ming, primary, Berglund, Anders E., primary, Silagy, Andrew W., primary, Mascareno, Eduardo A., primary, Golkaram, Mahdi, primary, Marker, Mahtab, primary, Reising, Albert, primary, Savchenko, Alexander, primary, Millholland, John, primary, Chen, Ying-Bei, primary, Russo, Paul, primary, Coleman, Jonathan, primary, Reznik, Ed, primary, Manley, Brandon J., primary, Ostrovnaya, Irina, primary, Makarov, Vladimir, primary, DiNatale, Renzo G., primary, Blum, Kyle A., primary, Ma, Xiaoxiao, primary, Chowell, Diego, primary, Li, Ming O., primary, Solit, David B., primary, Lowe, Scott W., primary, Chan, Timothy A., primary, Motzer, Robert J., primary, Voss, Martin H., primary, and Hakimi, A. Ari, primary

Published
2023
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27. Supplementary Figure from A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma

Author

Rappold, Phillip M., primary, Vuong, Lynda, primary, Leibold, Josef, primary, Chakiryan, Nicholas H., primary, Curry, Michael, primary, Kuo, Fengshen, primary, Sabio, Erich, primary, Jiang, Hui, primary, Nixon, Briana G., primary, Liu, Ming, primary, Berglund, Anders E., primary, Silagy, Andrew W., primary, Mascareno, Eduardo A., primary, Golkaram, Mahdi, primary, Marker, Mahtab, primary, Reising, Albert, primary, Savchenko, Alexander, primary, Millholland, John, primary, Chen, Ying-Bei, primary, Russo, Paul, primary, Coleman, Jonathan, primary, Reznik, Ed, primary, Manley, Brandon J., primary, Ostrovnaya, Irina, primary, Makarov, Vladimir, primary, DiNatale, Renzo G., primary, Blum, Kyle A., primary, Ma, Xiaoxiao, primary, Chowell, Diego, primary, Li, Ming O., primary, Solit, David B., primary, Lowe, Scott W., primary, Chan, Timothy A., primary, Motzer, Robert J., primary, Voss, Martin H., primary, and Hakimi, A. Ari, primary

Published
2023
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28. Data from A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma

Author

Rappold, Phillip M., primary, Vuong, Lynda, primary, Leibold, Josef, primary, Chakiryan, Nicholas H., primary, Curry, Michael, primary, Kuo, Fengshen, primary, Sabio, Erich, primary, Jiang, Hui, primary, Nixon, Briana G., primary, Liu, Ming, primary, Berglund, Anders E., primary, Silagy, Andrew W., primary, Mascareno, Eduardo A., primary, Golkaram, Mahdi, primary, Marker, Mahtab, primary, Reising, Albert, primary, Savchenko, Alexander, primary, Millholland, John, primary, Chen, Ying-Bei, primary, Russo, Paul, primary, Coleman, Jonathan, primary, Reznik, Ed, primary, Manley, Brandon J., primary, Ostrovnaya, Irina, primary, Makarov, Vladimir, primary, DiNatale, Renzo G., primary, Blum, Kyle A., primary, Ma, Xiaoxiao, primary, Chowell, Diego, primary, Li, Ming O., primary, Solit, David B., primary, Lowe, Scott W., primary, Chan, Timothy A., primary, Motzer, Robert J., primary, Voss, Martin H., primary, and Hakimi, A. Ari, primary

Published
2023
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29. Supplementary Data 2 from High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab

Author

Lee, Chung-Han, primary, DiNatale, Renzo G., primary, Chowell, Diego, primary, Krishna, Chirag, primary, Makarov, Vladimir, primary, Valero, Cristina, primary, Vuong, Lynda, primary, Lee, Mark, primary, Weiss, Kate, primary, Hoen, Doug, primary, Morris, Luc, primary, Reznik, Ed, primary, Murray, Samuel, primary, Kotecha, Ritesh, primary, Voss, Martin H., primary, Carlo, Maria I., primary, Feldman, Darren, primary, Sachdev, Pallavi, primary, Adachi, Yusuke, primary, Minoshima, Yukinori, primary, Matsui, Junji, primary, Funahashi, Yasuhiro, primary, Nomoto, Kenichi, primary, Hakimi, A. Ari, primary, Motzer, Robert J., primary, and Chan, Timothy A., primary

Published
2023
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30. Supplementary Data 1 from High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab

Author

Lee, Chung-Han, primary, DiNatale, Renzo G., primary, Chowell, Diego, primary, Krishna, Chirag, primary, Makarov, Vladimir, primary, Valero, Cristina, primary, Vuong, Lynda, primary, Lee, Mark, primary, Weiss, Kate, primary, Hoen, Doug, primary, Morris, Luc, primary, Reznik, Ed, primary, Murray, Samuel, primary, Kotecha, Ritesh, primary, Voss, Martin H., primary, Carlo, Maria I., primary, Feldman, Darren, primary, Sachdev, Pallavi, primary, Adachi, Yusuke, primary, Minoshima, Yukinori, primary, Matsui, Junji, primary, Funahashi, Yasuhiro, primary, Nomoto, Kenichi, primary, Hakimi, A. Ari, primary, Motzer, Robert J., primary, and Chan, Timothy A., primary

Published
2023
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31. Data from High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab

Author

Lee, Chung-Han, primary, DiNatale, Renzo G., primary, Chowell, Diego, primary, Krishna, Chirag, primary, Makarov, Vladimir, primary, Valero, Cristina, primary, Vuong, Lynda, primary, Lee, Mark, primary, Weiss, Kate, primary, Hoen, Doug, primary, Morris, Luc, primary, Reznik, Ed, primary, Murray, Samuel, primary, Kotecha, Ritesh, primary, Voss, Martin H., primary, Carlo, Maria I., primary, Feldman, Darren, primary, Sachdev, Pallavi, primary, Adachi, Yusuke, primary, Minoshima, Yukinori, primary, Matsui, Junji, primary, Funahashi, Yasuhiro, primary, Nomoto, Kenichi, primary, Hakimi, A. Ari, primary, Motzer, Robert J., primary, and Chan, Timothy A., primary

Published
2023
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32. Additional file 2 of Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape

Author

Golkaram, Mahdi, Kuo, Fengshen, Gupta, Sounak, Carlo, Maria I., Salmans, Michael L., Vijayaraghavan, Raakhee, Tang, Cerise, Makarov, Vlad, Rappold, Phillip, Blum, Kyle A., Zhao, Chen, Mehio, Rami, Zhang, Shile, Godsey, Jim, Pawlowski, Traci, DiNatale, Renzo G., Morris, Luc G. T., Durack, Jeremy, Russo, Paul, Kotecha, Ritesh R., Coleman, Jonathan, Chen, Ying-Bei, Reuter, Victor E., Motzer, Robert J., Voss, Martin H., Liu, Li, Reznik, Ed, Chan, Timothy A., and Hakimi, A. Ari

Abstract

Additional file2 Supplementary Figures: Provides additional data analysis supporting claims and conclusions drawn throughout the paper

Published
2023
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35. Figure S2 from Comprehensive Genomic Analysis of Translocation Renal Cell Carcinoma Reveals Copy-Number Variations as Drivers of Disease Progression

Author

Marcon, Julian, primary, DiNatale, Renzo G., primary, Sanchez, Alejandro, primary, Kotecha, Ritesh R., primary, Gupta, Sounak, primary, Kuo, Fengshen, primary, Makarov, Vladimir, primary, Sandhu, Amar, primary, Mano, Roy, primary, Silagy, Andrew W., primary, Blum, Kyle A., primary, Nassau, Daniel E., primary, Benfante, Nicole E., primary, Ortiz, Michael V., primary, Carlo, Maria I., primary, Chan, Timothy A., primary, Motzer, Robert J., primary, Voss, Martin H., primary, Coleman, Jonathan, primary, Russo, Paul, primary, Reuter, Victor, primary, Hakimi, A. Ari, primary, and Reznik, Ed, primary

Published
2023
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39. Urethral Melanoma – Clinical, Pathological and Molecular Characteristics

Author

Mano, Roy, primary, Hoeh, Benedikt, additional, DiNatale, Renzo G., additional, Sanchez, Alejandro, additional, Benfante, Nicole E., additional, Reznik, Ed, additional, Leitao, Mario M., additional, Shoushtari, Alexander N., additional, Goh, Alvin, additional, Donat, S. Machele, additional, Herr, Harry W., additional, Bochner, Bernard H., additional, Dalbagni, Guido, additional, and Donahue, Timothy F., additional

Published
2022
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41. Spatiotemporal evolution of the ccRCC microenvironment links intra-tumoral heterogeneity to immune escape

Author

Golkaram, Mahdi, primary, Kuo, Fengshen, additional, Gupta, Sounak, additional, Carlo, Maria I., additional, Salmans, Michael L., additional, Vijayaraghavan, Raakhee, additional, Tang, Cerise, additional, Makarov, Vlad, additional, Rappold, Phillip, additional, Blum, Kyle A., additional, Zhao, Chen, additional, Mehio, Rami, additional, Zhang, Shile, additional, Godsey, Jim, additional, Pawlowski, Traci, additional, DiNatale, Renzo G., additional, Morris, Luc GT, additional, Durack, Jeremy, additional, Kotecha, Ritesh R., additional, Russo, Paul, additional, Coleman, Jonathan, additional, Chen, Ying-Bei, additional, Reuter, Victor E, additional, Motzer, Robert J., additional, Voss, Martin H., additional, Liu, Li, additional, Reznik, Ed, additional, Chan, Timothy A., additional, and Hakimi, A Ari, additional

Published
2022
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42. A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma

Author

Rappold, Phillip M., primary, Vuong, Lynda, additional, Leibold, Josef, additional, Chakiryan, Nicholas H., additional, Curry, Michael, additional, Kuo, Fengshen, additional, Sabio, Erich, additional, Jiang, Hui, additional, Nixon, Briana G., additional, Liu, Ming, additional, Berglund, Anders E., additional, Silagy, Andrew W., additional, Mascareno, Eduardo A., additional, Golkaram, Mahdi, additional, Marker, Mahtab, additional, Reising, Albert, additional, Savchenko, Alexander, additional, Millholland, John, additional, Chen, Ying-Bei, additional, Russo, Paul, additional, Coleman, Jonathan, additional, Reznik, Ed, additional, Manley, Brandon J., additional, Ostrovnaya, Irina, additional, Makarov, Vladimir, additional, DiNatale, Renzo G., additional, Blum, Kyle A., additional, Ma, Xiaoxiao, additional, Chowell, Diego, additional, Li, Ming O., additional, Solit, David B., additional, Lowe, Scott W., additional, Chan, Timothy A., additional, Motzer, Robert J., additional, Voss, Martin H., additional, and Hakimi, A. Ari, additional

Published
2022
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44. PD16-07 NEUTROPHIL-TO-LYMPHOCYTE RATIO IN UNCLASSIFIED RENAL CELL CARCINOMA IS ASSOCIATED WITH OUTCOME AND DIFFERS BETWEEN MOLECULAR SUBGROUPS

Author

Marcon, Julian, primary, DiNatale, Renzo G., additional, Weng, Stanley, additional, Ghanaat, Mazyar, additional, Silagy, Andrew W., additional, Mano, Roy, additional, Blum, Kyle A., additional, Attalla, Kyrollis, additional, Reznik, Ed, additional, Carlo, Maria I., additional, Motzer, Robert J., additional, Coleman, Jonathan A., additional, Russo, Paul, additional, Hakimi, A. Ari, additional, and Chen, Ying-Bei, additional

Published
2021
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45. Evolving biological associations of upfront cytoreductive nephrectomy in metastatic renal cell carcinoma

Author

Silagy, Andrew W., primary, Kotecha, Ritesh R., additional, Weng, Stanley, additional, Holmes, Arturo, additional, Singla, Nirmish, additional, Mano, Roy, additional, Attalla, Kyrollis, additional, Weiss, Kate L., additional, DiNatale, Renzo G., additional, Patil, Sujata, additional, Coleman, Jonathan A., additional, Motzer, Robert J., additional, Russo, Paul, additional, Voss, Martin H., additional, and Hakimi, A. Ari, additional

Published
2021
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46. Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma

Author

Attalla, Kyrollis, primary, DiNatale, Renzo G., additional, Rappold, Phillip M., additional, Fong, Christopher J., additional, Sanchez-Vega, Francisco, additional, Silagy, Andrew W., additional, Weng, Stanley, additional, Coleman, Jonathan, additional, Lee, Chung-Han, additional, Carlo, Maria I., additional, Durack, Jeremy C., additional, Solomon, Stephen B., additional, Reuter, Victor E., additional, Russo, Paul, additional, Chan, Timothy A., additional, Motzer, Robert J., additional, Schultz, Nikolaus D., additional, Reznik, Ed, additional, Voss, Martin H., additional, and Hakimi, A. Ari, additional

Published
2021
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47. Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

Author

Nguyen, Bastien, primary, Fong, Christopher, additional, Luthra, Anisha, additional, Smith, Shaleigh A., additional, DiNatale, Renzo G., additional, Nandakumar, Subhiksha, additional, Walch, Henry, additional, Chatila, Walid K., additional, Madupuri, Ramyasree, additional, Kundra, Ritika, additional, Bielski, Craig M., additional, Mastrogiacomo, Brooke, additional, Boire, Adrienne, additional, Chandarlapaty, Sarat, additional, Ganesh, Karuna, additional, Harding, James J., additional, lacobuzio-Donahue, Christine A., additional, Razavi, Pedram, additional, Reznik, Ed, additional, Rudin, Charles M., additional, Zamarin, Dmitriy, additional, Abida, Wassim, additional, Abou-Alfa, Ghassan K., additional, Aghajanian, Carol, additional, Cercek, Andrea, additional, Chi, Ping, additional, Feldman, Darren, additional, Ho, Alan L., additional, Iyer, Gopakumar, additional, Janjigian, Yelena Y., additional, Morris, Michael, additional, Motzer, Robert J., additional, O’Reilly, Eileen M., additional, Postow, Michael A., additional, Raj, Nitya P., additional, Riely, Gregory J., additional, Robson, Mark E., additional, Rosenberg, Jonathan E., additional, Safonov, Anton, additional, Shoushtari, Alexander N., additional, Tap, William, additional, Teo, Min Yuen, additional, Varghese, Anna M., additional, Voss, Martin, additional, Yaeger, Rona, additional, Zauderer, Marjorie G., additional, Abu-Rustum, Nadeem, additional, Garcia-Aguilar, Julio, additional, Bochner, Bernard, additional, Hakimi, Abraham, additional, Jarnagin, William R., additional, Jones, David R., additional, Molena, Daniela, additional, Morris, Luc, additional, Rios-Doria, Eric, additional, Russo, Paul, additional, Singer, Samuel, additional, Strong, Vivian E., additional, Chakravarty, Debyani, additional, Ellenson, Lora H., additional, Gopalan, Anuradha, additional, Reis-Filho, Jorge S., additional, Weigelt, Britta, additional, Ladanyi, Marc, additional, Gonen, Mithat, additional, Shah, Sohrab P., additional, Massague, Joan, additional, Gao, Jianjiong, additional, Zehir, Ahmet, additional, Berger, Michael F., additional, Solit, David B., additional, Bakhoum, Samuel F., additional, Sanchez-Vega, Francisco, additional, and Schultz, Nikolaus, additional

Published
2021
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48. Resource-efficient pooled sequencing expands translational impact in solid tumors

Author

DiNatale, Renzo G., primary, Mano, Roy, additional, Makarov, Vladimir, additional, Rusk, Nicole, additional, Drill, Esther, additional, Winer, Andrew, additional, Sankin, Alexander, additional, Yoo, Angela, additional, Freeman, Benjamin A., additional, Hsieh, James J., additional, Chen, Ying-Bei, additional, Coleman, Jonathan A., additional, Berger, Michael, additional, Ostrovnaya, Irina, additional, Chan, Timothy A., additional, Russo, Paul, additional, Reznik, Ed, additional, and Hakimi, A. Ari, additional

Published
2021
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49. High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab

Author

Lee, Chung-Han, primary, DiNatale, Renzo G., additional, Chowell, Diego, additional, Krishna, Chirag, additional, Makarov, Vladimir, additional, Valero, Cristina, additional, Vuong, Lynda, additional, Lee, Mark, additional, Weiss, Kate, additional, Hoen, Doug, additional, Morris, Luc, additional, Reznik, Ed, additional, Murray, Samuel, additional, Kotecha, Ritesh, additional, Voss, Martin H., additional, Carlo, Maria I., additional, Feldman, Darren, additional, Sachdev, Pallavi, additional, Adachi, Yusuke, additional, Minoshima, Yukinori, additional, Matsui, Junji, additional, Funahashi, Yasuhiro, additional, Nomoto, Kenichi, additional, Hakimi, A. Ari, additional, Motzer, Robert J., additional, and Chan, Timothy A., additional

Published
2021
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50. Putative Drivers of Aggressiveness in TCEB1-mutant Renal Cell Carcinoma: An Emerging Entity with Variable Clinical Course

Author

DiNatale, Renzo G., primary, Gorelick, Alexander N., additional, Makarov, Vladimir, additional, Blum, Kyle A., additional, Silagy, Andrew W., additional, Freeman, Benjamin, additional, Chowell, Diego, additional, Marcon, Julian, additional, Mano, Roy, additional, Sanchez, Alex, additional, Attalla, Kyrollis, additional, Weng, Stanley, additional, Voss, Martin, additional, Motzer, Robert J., additional, Russo, Paul, additional, Coleman, Jonathan A., additional, Reuter, Victor E., additional, Chen, Ying-Bei, additional, Chan, Timothy A., additional, Reznik, Ed, additional, Tickoo, Satish K., additional, and Hakimi, A. Ari, additional

Published
2021
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