189 results on '"Dichiara, Maria"'
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2. A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients
3. Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity
4. Design, Synthesis, and Cytotoxic Assessment of New Haloperidol Analogues as Potential Anticancer Compounds Targeting Sigma Receptors
5. Biostimulants for Sustainable Food Production: Effects of Wood Distillate to Fortify Chickpea Flour for Development of Functional Bakery Products
6. Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation
7. Exploring Structural Requirements for Sigma‑1 Receptor Linear Ligands: Experimental and Computational Approaches.
8. Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition
9. Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus
10. Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity
11. Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines
12. Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents
13. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
14. Structure–Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis
15. New Insights into the Opioid Analgesic Profile of cis-(−)-N-Normetazocine-derived Ligands
16. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands
17. Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition
18. Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands
19. Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
20. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis
21. CREB Binding Protein is a Required Coactivator for Smad-Dependent, Transforming Growth Factor β Transcriptional Responses in Endothelial Cells
22. Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands
23. Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity.
24. Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands
25. H2S releasing molecules in pharmaceutical development
26. Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain
27. Correction to “Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents”
28. Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5’‐monophosphate glycosidase
29. Dual Piperidine-Based Histamine H3 and Sigma‑1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.
30. Dual Piperidine-Based Histamine H3and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
31. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties
32. Haloperidol Metabolite II Valproate Ester (S)-(−)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma
33. Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents
34. Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity
35. Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinityElectronic supplementary information (ESI) available: (a) Synthetic procedure for preparing compound 1; (b) protocol validation of computational studies. See DOI: https://doi.org/10.1039/d3md00291h
36. Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1
37. Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation
38. Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist
39. Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists
40. Tuning Properties for Blood–Brain Barrier Permeation: A Statistics-Based Analysis
41. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma‑1 Receptor Antagonists with Promising Antinociceptive Properties.
42. CNS permeability parameters determination through a statistical analysis driven approach
43. Development of novel H2S-donor sigma receptor hybrids for the management of pain
44. La modellistica molecolare applicata ai recettori Sigma-1 e Sigma-2: un excursus
45. Development of NO-releasing sigma receptor hybrids as anticancer agents
46. CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor-beta transcriptional responses in endothelial cells
47. H2S-releasing molecules in pharmaceutical development.
48. The Egr-1 promoter contains information for constitutive and inducible expression in transgenic mice1
49. Inhibition of E-Selectin Gene Expression by Transforming Growth Factor β in Endothelial Cells Involves Coactivator Integration of Smad and Nuclear Factor κB-mediated Signals
50. New selective Sigma-1/HDACi prodrugs for neurodegenerative disorders
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