26 results on '"Digby, Gregory J."'
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2. Supplementary Figures 1-5 from GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon
3. Data from GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon
4. The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo
5. G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons
6. Some G Protein Heterotrimers Physically Dissociate in Living Cells
7. A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS
8. Differential dissociation of G protein heterotrimers
9. Further exploration of M1 allosteric agonists: Subtle structural changes abolish M1 allosteric agonism and result in pan-mAChR orthosteric antagonism
10. Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs
11. The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo
12. Development of a highly selective, orally bioavailable and CNS penetrant M 1 agonist derived from the MLPCN probe ML071
13. Differential dissociation of G protein heterotrimers
14. A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS*S⃞
15. Chemical Modification of the M1 Agonist VU0364572 Reveals Molecular Switches in Pharmacology and a Bitopic Binding Mode
16. Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071
17. Measuring arrestin binding to G Protein Coupled Receptors: BRET and recruitment assays tell different stories.
18. Allosteric activators of muscarinic receptors as novel approaches for treatment of CNS disorders
19. The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers
20. GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon
21. Rapid Binding of Gβγ Dimers to the c-terminus of GRK3
22. Novel Allosteric Agonists of M1 Muscarinic Acetylcholine Receptors Induce Brain Region-Specific Responses That Correspond with Behavioral Effects in Animal Models.
23. Development of a highly selective, orally bioavailable and CNS penetrant M1 agonist derived from the MLPCN probe ML071
24. Further exploration of M1 allosteric agonists: Subtle structural changes abolish M1 allosteric agonism and result in pan-mAChR orthosteric antagonism
25. Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models.
26. Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs.
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