238 results on '"Dikilitas, Ozan"'
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2. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
3. Abstract 4140097: Effect of Disclosing a Polygenic Risk Score for Coronary Heart Disease on Adverse Cardiovascular Events: 10-year Follow-up of the MI-GENES Randomized Clinical Trial
4. Abstract 4137518: The implications of polygenic versus phenotypic characterization of obesity for cardiovascular-kidney-metabolic health
5. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
6. Author Correction: Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection
7. Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection
8. Evaluation of the portability of computable phenotypes with natural language processing in the eMERGE network
9. Polygenic Risk, Rare Variants, and Family History: Independent and Additive Effects on Coronary Heart Disease
10. Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets
11. Returning integrated genomic risk and clinical recommendations: The eMERGE study
12. Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid
13. Abstract 15960: Mortality Differences Among Myocardial Injury Subtypes in Acute COVID-19, the Omicron Wave Was Different
14. Abstract 15784: Clonal Hematopoiesis of Indeterminate Potential is Associated With Increased Risk of Incident Hypertension
15. Abstract 15706: Common- and Rare-Variant Genetic Architecture of Heart Failure Across the Allele Frequency Spectrum
16. Abstract 13711: Clonal Hematopoiesis Driven by TET2 and ASXL1 but Not DNMT3A is Associated With Interleukin 6 Levels, Cardiac Biomarkers, Cardiac Remodeling, and Risk of Atrial Fibrillation
17. Abstract 12827: Daylight Savings Time Practice and the Rate of Adverse Cardiovascular Events in the United States: A Probabilistic Assessment in a Large Nationwide Study
18. Multiancestral polygenic risk score for pediatric asthma
19. Use of Polygenic Risk Scores for Coronary Heart Disease in Ancestrally Diverse Populations
20. Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
21. Genome-wide polygenic score to predict chronic kidney disease across ancestries
22. Transgelin: a new gene involved in LDL endocytosis identified by a genome-wide CRISPR-Cas9 screen
23. Neptune: an environment for the delivery of genomic medicine
24. Under-specification as the source of ambiguity and vagueness in narrative phenotype algorithm definitions
25. Author Correction: Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases
26. Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations
27. Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure
28. Leveraging the Electronic Health Record to Address the COVID-19 Pandemic
29. Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk
30. Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups
31. Abstract 13386: The Association of High Polygenic Risk With Future Coronary Heart Disease Events Diminishes Later in Life
32. Abstract 10822: Familial Hypercholesterolemia in the EMERGE Network: 1-Year Outcomes After Return of Results
33. Atrial Fibrillation and Clonal Hematopoiesis in TET2 and ASXL1
34. Making work visible for electronic phenotype implementation: Lessons learned from the eMERGE network
35. Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network
36. Facilitating phenotype transfer using a common data model
37. Daylight Saving Time Practice and the Rate of Adverse Cardiovascular Events in the United States: A Probabilistic Assessment in a Large Nationwide Study
38. Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases
39. Author Correction: Genetic basis of hypercholesterolemia in adults
40. Genetic basis of hypercholesterolemia in adults
41. Super and Nonresponders to Catheter Ablation for Atrial Fibrillation: A Quality-of-Life Assessment Using Patient Reported Outcomes
42. Abstract 15273: Estimating Coronary Heart Disease Risk and Treatment Benefit in Patients With Familial Hypercholesterolemia to Enable Shared Decision Making
43. Abstract 15209: LPA Variants Are Associated With Aortic Valve Stenosis, Heart Failure and Chronic Kidney Disease
44. Abstract 14663: High Rate of Arrhythmia Diagnoses Following Return of Pathogenic/likely Pathogenic Variants in an Unselected Population
45. Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program
46. A Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization
47. Returning integrated genomic risk and clinical recommendations: The eMERGE study
48. Familial Hypercholesterolemia in the Electronic Medical Records and Genomics Network: Prevalence, Penetrance, Cardiovascular Risk, and Outcomes After Return of Results
49. Genetic Predictors of Blood Pressure Traits are Associated with Preeclampsia
50. S-22-4: GENOME WIDE ASSOCIATION STUDY OF FIBROMUSCULAR DYSPLASIA REVEALS MECHANISTIC LINKS WITH BLOOD PRESSURE REGULATION AND OTHER VASCULAR DISEASES
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