Search

Your search keyword '"Ding, Peiwen"' showing total 35 results
Start Over Author "Ding, Peiwen"
35 results on '"Ding, Peiwen"'

2. Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Author

Wang, Fei, Ding, Peiwen, Liang, Xue, Ding, Xiangning, Brandt, Camilla Blunk, Sjöstedt, Evelina, Zhu, Jiacheng, Bolund, Saga, Zhang, Lijing, de Rooij, Laura P. M. H., Luo, Lihua, Wei, Yanan, Zhao, Wandong, Lv, Zhiyuan, Haskó, János, Li, Runchu, Qin, Qiuyu, Jia, Yi, Wu, Wendi, Yuan, Yuting, Pu, Mingyi, Wang, Haoyu, Wu, Aiping, Xie, Lin, Liu, Ping, Chen, Fang, Herold, Jacqueline, Kalucka, Joanna, Karlsson, Max, Zhang, Xiuqing, Helmig, Rikke Bek, Fagerberg, Linn, Lindskog, Cecilia, Pontén, Fredrik, Uhlen, Mathias, Bolund, Lars, Jessen, Niels, Jiang, Hui, Xu, Xun, Yang, Huanming, Carmeliet, Peter, Mulder, Jan, Chen, Dongsheng, Lin, Lin, and Luo, Yonglun

Published
2022
Full Text
View/download PDF

3. Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Author

Wang, Fei, Ding, Peiwen, Liang, Xue, Ding, Xiangning, Brandt, Camilla Blunk, Sjöstedt, Evelina, Zhu, Jiacheng, Bolund, Saga, Zhang, Lijing, de Rooij, Laura P. M. H., Luo, Lihua, Wei, Yanan, Zhao, Wandong, Lv, Zhiyuan, Haskó, János, Li, Runchu, Qin, Qiuyu, Jia, Yi, Wu, Wendi, Yuan, Yuting, Pu, Mingyi, Wang, Haoyu, Wu, Aiping, Xie, Lin, Liu, Ping, Chen, Fang, Herold, Jacqueline, Kalucka, Joanna, Karlsson, Max, Zhang, Xiuqing, Helmig, Rikke Bek, Fagerberg, Linn, Lindskog, Cecilia, Pontén, Fredrik, Uhlen, Mathias, Bolund, Lars, Jessen, Niels, Jiang, Hui, Xu, Xun, Yang, Huanming, Carmeliet, Peter, Mulder, Jan, Chen, Dongsheng, Lin, Lin, and Luo, Yonglun

Published
2022
Full Text
View/download PDF

5. Single-cell atlas of domestic pig cerebral cortex and hypothalamus

Author

Zhu, Jiacheng, Chen, Fang, Luo, Lihua, Wu, Weiying, Dai, Jinxia, Zhong, Jixing, Lin, Xiumei, Chai, Chaochao, Ding, Peiwen, Liang, Langchao, Wang, Shiyou, Ding, Xiangning, Chen, Yin, Wang, Haoyu, Qiu, Jiaying, Wang, Feiyue, Sun, Chengcheng, Zeng, Yuying, Fang, Jian, Jiang, Xiaosen, Liu, Ping, Tang, Gen, Qiu, Xin, Zhang, Xingliang, Ruan, Yetian, Jiang, Sanjie, Li, Jiankang, Zhu, Shida, Xu, Xun, Li, Fang, Liu, Zhongmin, Cao, Gang, and Chen, Dongsheng

Published
2021
Full Text
View/download PDF

6. The trans-omics landscape of COVID-19

Author

Wu, Peng, Chen, Dongsheng, Ding, Wencheng, Wu, Ping, Hou, Hongyan, Bai, Yong, Zhou, Yuwen, Li, Kezhen, Xiang, Shunian, Liu, Panhong, Ju, Jia, Guo, Ensong, Liu, Jia, Yang, Bin, Fan, Junpeng, He, Liang, Sun, Ziyong, Feng, Ling, Wang, Jian, Wu, Tangchun, Wang, Hao, Cheng, Jin, Xing, Hui, Meng, Yifan, Li, Yongsheng, Zhang, Yuanliang, Luo, Hongbo, Xie, Gang, Lan, Xianmei, Tao, Ye, Li, Jiafeng, Yuan, Hao, Huang, Kang, Sun, Wan, Qian, Xiaobo, Li, Zhichao, Huang, Mingxi, Ding, Peiwen, Wang, Haoyu, Qiu, Jiaying, Wang, Feiyue, Wang, Shiyou, Zhu, Jiacheng, Ding, Xiangning, Chai, Chaochao, Liang, Langchao, Wang, Xiaoling, Luo, Lihua, Sun, Yuzhe, Yang, Ying, Zhuang, Zhenkun, Li, Tao, Tian, Lei, Zhang, Shaoqiao, Zhu, Linnan, Chang, Ashley, Chen, Lei, Wu, Yiquan, Ma, Xiaoyan, Chen, Fang, Ren, Yan, Xu, Xun, Liu, Siqi, Wang, Jian, Yang, Huanming, Wang, Lin, Sun, Chaoyang, Ma, Ding, Jin, Xin, and Chen, Gang

Published
2021
Full Text
View/download PDF

7. Single cell atlas for 11 non-model mammals, reptiles and birds

Author

Chen, Dongsheng, Sun, Jian, Zhu, Jiacheng, Ding, Xiangning, Lan, Tianming, Wang, Xiran, Wu, Weiying, Ou, Zhihua, Zhu, Linnan, Ding, Peiwen, Wang, Haoyu, Luo, Lihua, Xiang, Rong, Wang, Xiaoling, Qiu, Jiaying, Wang, Shiyou, Li, Haimeng, Chai, Chaochao, Liang, Langchao, An, Fuyu, Zhang, Le, Han, Lei, Zhu, Yixin, Wang, Feiyue, Yuan, Yuting, Wu, Wendi, Sun, Chengcheng, Lu, Haorong, Wu, Jihong, Sun, Xinghuai, Zhang, Shenghai, Sahu, Sunil Kumar, Liu, Ping, Xia, Jun, Zhang, Lijing, Chen, Haixia, Fang, Dongming, Zeng, Yuying, Wu, Yiquan, Cui, Zehua, He, Qian, Jiang, Sanjie, Ma, Xiaoyan, Feng, Weimin, Xu, Yan, Li, Fang, Liu, Zhongmin, Chen, Lei, Chen, Fang, Jin, Xin, Qiu, Wei, Wang, Tianjiao, Li, Yang, Xing, Xiumei, Yang, Huanming, Xu, Yanchun, Hua, Yan, Liu, Yahong, Liu, Huan, and Xu, Xun

Published
2021
Full Text
View/download PDF

10. Author Correction:Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level (Nature Communications, (2022), 13, 1, (3620), 10.1038/s41467-022-31388-z)

Author

Wang, Fei, Ding, Peiwen, Liang, Xue, Ding, Xiangning, Brandt, Camilla Blunk, Sjöstedt, Evelina, Zhu, Jiacheng, Bolund, Saga, Zhang, Lijing, de Rooij, Laura P.M.H., Luo, Lihua, Wei, Yanan, Zhao, Wandong, Lv, Zhiyuan, Haskó, János, Li, Runchu, Qin, Qiuyu, Jia, Yi, Wu, Wendi, Yuan, Yuting, Pu, Mingyi, Wang, Haoyu, Wu, Aiping, Xie, Lin, Liu, Ping, Chen, Fang, Herold, Jacqueline, Kalucka, Joanna, Karlsson, Max, Zhang, Xiuqing, Helmig, Rikke Bek, Fagerberg, Linn, Lindskog, Cecilia, Pontén, Fredrik, Uhlen, Mathias, Bolund, Lars, Jessen, Niels, Jiang, Hui, Xu, Xun, Yang, Huanming, Carmeliet, Peter, Mulder, Jan, Chen, Dongsheng, Lin, Lin, and Luo, Yonglun

Published
2022

12. Viral receptor profiles of masked palm civet revealed by single-cell transcriptomics

Author

Ding, Peiwen, primary, Wang, Haoyu, additional, Zhu, Jiacheng, additional, An, Fuyu, additional, Xu, Jinqian, additional, Ding, Xiangning, additional, Luo, Lihua, additional, Wu, Weiying, additional, Qin, Qiuyu, additional, Wei, Yanan, additional, Zhao, Wandong, additional, Lv, Zhiyuan, additional, Li, Haimeng, additional, Zhu, Yixin, additional, Li, Meiling, additional, Zhang, Wensheng, additional, Zhang, Yanan, additional, Ou, Zhihua, additional, Liu, Huan, additional, and Hua, Yan, additional

Published
2022
Full Text
View/download PDF

13. SPEED: Single-cell Pan-species atlas in the light of Ecology and Evolution for Development and Diseases

Author

Chen, Yangfeng, primary, Zhang, Xingliang, additional, Peng, Xi, additional, Jin, Yicheng, additional, Ding, Peiwen, additional, Xiao, Jiedan, additional, Li, Changxiao, additional, Wang, Fei, additional, Chang, Ashley, additional, Yue, Qizhen, additional, Pu, Mingyi, additional, Chen, Peixin, additional, Shen, Jiayi, additional, Li, Mengrou, additional, Jia, Tengfei, additional, Wang, Haoyu, additional, Huang, Li, additional, Guo, Guoji, additional, Zhang, Wensheng, additional, Liu, Hebin, additional, Wang, Xiangdong, additional, and Chen, Dongsheng, additional

Published
2022
Full Text
View/download PDF

14. Comparative analysis of single cell lung atlas of bat, cat, tiger, and pangolin

Author

Wang, Xiran, primary, Ding, Peiwen, additional, Sun, Chengcheng, additional, Wang, Daxi, additional, Zhu, Jiacheng, additional, Wu, Wendi, additional, Wei, Yanan, additional, Xiang, Rong, additional, Ding, Xiangning, additional, Luo, Lihua, additional, Li, Meiling, additional, Zhang, Wensheng, additional, Jin, Xin, additional, Sun, Jian, additional, Liu, Huan, additional, and Chen, Dongsheng, additional

Published
2022
Full Text
View/download PDF

15. Screening of cell‐virus, cell‐cell, gene‐gene crosstalk among animal kingdom at single cell resolution

Author

Chen, Dongsheng, primary, Ou, Zhihua, additional, Zhu, Jiacheng, additional, Wang, Haoyu, additional, Ding, Peiwen, additional, Luo, Lihua, additional, Ding, Xiangning, additional, Sun, Chengcheng, additional, Lan, Tianming, additional, Sahu, Sunil Kumar, additional, Wu, Weiying, additional, Yuan, Yuting, additional, Wu, Wendi, additional, Qiu, Jiaying, additional, Zhu, Yixin, additional, Yue, Qizhen, additional, Jia, Yi, additional, Wei, Yanan, additional, Qin, Qiuyu, additional, Li, Runchu, additional, Zhao, Wandong, additional, Lv, Zhiyuan, additional, Pu, Mingyi, additional, Lv, Boqiong, additional, Yang, Shangchen, additional, Chang, Ashley, additional, Wei, Xiaofeng, additional, Chen, Fengzhen, additional, Yang, Tao, additional, Wei, Zhenyong, additional, Yang, Fan, additional, Zhang, Peijing, additional, Guo, Guoji, additional, Li, Yuejiao, additional, Hua, Yan, additional, and Liu, Huan, additional

Published
2022
Full Text
View/download PDF

16. Joint profiling of gene expression and chromatin accessibility during amphioxus development at single-cell resolution

Author

Ma, Pengcheng, primary, Liu, Xingyan, additional, Xu, Zaoxu, additional, Liu, Huimin, additional, Ding, Xiangning, additional, Huang, Zhen, additional, Shi, Chenggang, additional, Liang, Langchao, additional, Xu, Luohao, additional, Li, Xiaolu, additional, Li, Guimei, additional, He, Yuqi, additional, Ding, Zhaoli, additional, Chai, Chaochao, additional, Wang, Haoyu, additional, Qiu, Jiaying, additional, Zhu, Jiacheng, additional, Wang, Xiaoling, additional, Ding, Peiwen, additional, Zhou, Si, additional, Yuan, Yuting, additional, Wu, Wendi, additional, Wan, Cen, additional, Yan, Yanan, additional, Zhou, Yitao, additional, Zhou, Qi-Jun, additional, Wang, Guo-Dong, additional, Zhang, Qiujin, additional, Xu, Xun, additional, Li, Guang, additional, Zhang, Shihua, additional, Mao, Bingyu, additional, and Chen, Dongsheng, additional

Published
2022
Full Text
View/download PDF

18. Molecular mechanisms governing circulating immune cell heterogeneity across different species revealed by single‐cell sequencing

Author

Li, Zhibin, primary, Sun, Chengcheng, additional, Wang, Fei, additional, Wang, Xiran, additional, Zhu, Jiacheng, additional, Luo, Lihua, additional, Ding, Xiangning, additional, Zhang, Yanan, additional, Ding, Peiwen, additional, Wang, Haoyu, additional, Pu, Mingyi, additional, Li, Yuejiao, additional, Wang, Shiyou, additional, Qin, Qiuyu, additional, Wei, Yanan, additional, Sun, Jian, additional, Wang, Xiangdong, additional, Luo, Yonglun, additional, Chen, Dongsheng, additional, and Qiu, Wei, additional

Published
2022
Full Text
View/download PDF

19. Comparative analysis of single cell lung atlas of bat, cat, tiger and pangolin

Author

Wang, Xiran, primary, Ou, Zhihua, additional, Ding, Peiwen, additional, Sun, Chengcheng, additional, Wang, Daxi, additional, Zhu, Jiacheng, additional, Wu, Wendi, additional, Wei, Yanan, additional, Ding, Xiangning, additional, Luo, Lihua, additional, Li, Meiling, additional, Zhang, Wensheng, additional, Jin, Xin, additional, Sun, Jian, additional, Liu, Huan, additional, and Chen, Dongsheng, additional

Published
2021
Full Text
View/download PDF

20. Molecular mechanisms governing circulating immune cell heterogeneity across different species revealed by single cell sequencing

Author

Li, Zhibin, primary, Sun, Chengcheng, additional, Wang, Fei, additional, Wang, Xiran, additional, Zhu, Jiacheng, additional, Luo, Lihua, additional, Ding, Xiangning, additional, Zhang, Yanan, additional, Ding, Peiwen, additional, Wang, Haoyu, additional, Pu, Mingyi, additional, Li, Yuejiao, additional, Wang, Shiyou, additional, Qin, Qiuyu, additional, Wei, Yanan, additional, Sun, Jian, additional, Wang, Xiangdong, additional, Luo, Yonglun, additional, Chen, Dongsheng, additional, and Qiu, Wei, additional

Published
2021
Full Text
View/download PDF

21. VThunter: a database for single-cell screening of virus target cells in the animal kingdom

Author

Chen, Dongsheng, primary, Tan, Cong, additional, Ding, Peiwen, additional, Luo, Lihua, additional, Zhu, Jiacheng, additional, Jiang, Xiaosen, additional, Ou, Zhihua, additional, Ding, Xiangning, additional, Lan, Tianming, additional, Zhu, Yixin, additional, Jia, Yi, additional, Wei, Yanan, additional, Li, Runchu, additional, Qin, Qiuyu, additional, Sun, Chengcheng, additional, Zhao, Wandong, additional, Lv, Zhiyuan, additional, Wang, Haoyu, additional, Wu, Wendi, additional, Yuan, Yuting, additional, Pu, Mingyi, additional, Li, Yuejiao, additional, Zhang, Yanan, additional, Chang, Ashley, additional, Guo, Guoji, additional, Bai, Yong, additional, Jin, Xin, additional, and Liu, Huan, additional

Published
2021
Full Text
View/download PDF

22. Screening of cell-virus, cell-cell, gene-gene cross-talks among kingdoms of life at single cell resolution

Author

Chen, Dongsheng, primary, Ou, Zhihua, additional, Zhu, Jiacheng, additional, Ding, Peiwen, additional, Wang, Haoyu, additional, Luo, Lihua, additional, Ding, Xiangning, additional, Lan, Tianming, additional, Wu, Weiying, additional, Yuan, Yuting, additional, Wu, Wendi, additional, Qiu, Jiaying, additional, Zhu, Yixin, additional, Jia, Yi, additional, Wei, Yanan, additional, Qin, Qiuyu, additional, Li, Runchu, additional, Sun, Chengcheng, additional, Zhao, Wandong, additional, Lv, Zhiyuan, additional, Pu, Mingyi, additional, Yang, Shangchen, additional, Chang, Ashley, additional, Wei, Xiaofeng, additional, Chen, Fengzhen, additional, Yang, Tao, additional, Wei, Zhenyong, additional, Yang, Fan, additional, Li, Yuejiao, additional, Hua, Yan, additional, and Liu, Huan, additional

Published
2021
Full Text
View/download PDF

23. Viral receptor profiles of masked palm civet revealed by single-cell transcriptomics

Author

Chen, Dongsheng, primary, Ou, Zhihua, additional, Wang, Haoyu, additional, Zhang, Yanan, additional, Zhu, Jiacheng, additional, An, Fuyu, additional, Xu, Jinqian, additional, Ding, Xiangning, additional, Ding, Peiwen, additional, Luo, Lihua, additional, Wu, Weiying, additional, Qin, Qiuyu, additional, Wei, Yanan, additional, Zhao, Wandong, additional, Lv, Zhiyuan, additional, Lan, Tianming, additional, Li, Meiling, additional, Zhang, Wensheng, additional, Liu, Huan, additional, and Hua, Yan, additional

Published
2021
Full Text
View/download PDF

24. Joint profiling of gene expression and chromatin accessibility of amphioxus development at single cell resolution

Author

Ma, Pengcheng, primary, Liu, Xingyan, additional, Liu, Huimin, additional, Xu, Zaoxu, additional, Ding, Xiangning, additional, Huang, Zhen, additional, Shi, Chenggang, additional, Liang, Langchao, additional, Xu, Luohao, additional, Li, Xiaolu, additional, Li, Guimei, additional, He, Yuqi, additional, Ding, Zhaoli, additional, Chai, Chaochao, additional, Wang, Haoyu, additional, Qiu, Jiaying, additional, Zhu, Jiacheng, additional, Wang, Xiaoling, additional, Ding, Peiwen, additional, Zhou, Si, additional, Yuan, Yuting, additional, Wu, Wendi, additional, Yan, Yanan, additional, Zhou, Yitao, additional, Zhou, Qi-Jun, additional, Wang, Guo-Dong, additional, Zhang, Qiujin, additional, Xu, Xun, additional, Li, Guang, additional, Zhang, Shihua, additional, Mao, Bingyu, additional, and Chen, Dongsheng, additional

Published
2021
Full Text
View/download PDF

26. A single-cell atlas of mouse olfactory bulb chromatin accessibility

Author

Chen, Yin, primary, Ding, Xiangning, additional, Wang, Shiyou, additional, Ding, Peiwen, additional, Xu, Zaoxu, additional, Li, Jiankang, additional, Wang, Mingyue, additional, Xiang, Rong, additional, Wang, Xiaoling, additional, Wang, Haoyu, additional, Feng, Qikai, additional, Qiu, Jiaying, additional, Wang, Feiyue, additional, Huang, Zhen, additional, Zhang, Xingliang, additional, Tang, Gen, additional, and Tang, Shengping, additional

Published
2021
Full Text
View/download PDF

28. The Trans-omics Landscape of COVID-19

Author

Wu, Peng, primary, Chen, Dongsheng, additional, Ding, Wencheng, additional, Wu, Ping, additional, Hou, Hongyan, additional, Bai, Yong, additional, Zhou, Yuwen, additional, Li, Kezhen, additional, Xiang, Shunian, additional, Liu, Panhong, additional, Ju, Jia, additional, Guo, Ensong, additional, Liu, Jia, additional, Yang, Bin, additional, Fan, Junpeng, additional, He, Liang, additional, Sun, Ziyong, additional, Feng, Ling, additional, Wang, Jian, additional, Wu, Tangchun, additional, Wang, Hao, additional, Cheng, Jin, additional, Xing, Hui, additional, Meng, Yifan, additional, Li, Yongsheng, additional, Zhang, Yuanliang, additional, Luo, Hongbo, additional, Xie, Gang, additional, Lan, Xianmei, additional, Tao, Ye, additional, Li, Jiafeng, additional, Yuan, Hao, additional, Huang, Kang, additional, Sun, Wan, additional, Qian, Xiaobo, additional, Li, Zhichao, additional, Huang, Mingxi, additional, Ding, Peiwen, additional, Wang, Haoyu, additional, Qiu, Jiaying, additional, Wang, Feiyue, additional, Wang, Shiyou, additional, Zhu, Jiacheng, additional, Ding, Xiangning, additional, Chai, Chaochao, additional, Liang, Langchao, additional, Wang, Xiaoling, additional, Luo, Lihua, additional, Sun, Yuzhe, additional, Yang, Ying, additional, Zhuang, Zhenkun, additional, Li, Tao, additional, Tian, Lei, additional, Zhang, Shaoqiao, additional, Zhu, Linnan, additional, Chang, Ashley, additional, Chen, Lei, additional, Wu, Yiquan, additional, Ma, Xiaoyan, additional, Chen, Fang, additional, Ren, Yan, additional, Xu, Xun, additional, Liu, Siqi, additional, Yang, Huanming, additional, Wang, Lin, additional, Sun, Chaoyang, additional, Ma, Ding, additional, Jin, Xin, additional, and Chen, Gang, additional

Published
2020
Full Text
View/download PDF

29. Single-cell screening of SARS-CoV-2 target cells in pets, livestock, poultry and wildlife

Author

Chen, Dongsheng, primary, Sun, Jian, additional, Zhu, Jiacheng, additional, Ding, Xiangning, additional, Lan, Tianming, additional, Zhu, Linnan, additional, Xiang, Rong, additional, Ding, Peiwen, additional, Wang, Haoyu, additional, Wang, Xiaoling, additional, Wu, Weiying, additional, Qiu, Jiaying, additional, Wang, Shiyou, additional, Li, Haimeng, additional, An, Fuyu, additional, Bao, Heng, additional, Zhang, Le, additional, Han, Lei, additional, Zhu, Yixin, additional, Wang, Xiran, additional, Wang, Feiyue, additional, Yuan, Yuting, additional, Wu, Wendi, additional, Sun, Chengcheng, additional, Lu, Haorong, additional, Wu, Jihong, additional, Sun, Xinghuai, additional, Zhang, Shenghai, additional, Sahu, Sunil Kumar, additional, Chen, Haixia, additional, Fang, Dongming, additional, Luo, Lihua, additional, Zeng, Yuying, additional, Wu, Yiquan, additional, Cui, ZeHua, additional, He, Qian, additional, Jiang, Sanjie, additional, Ma, Xiaoyan, additional, Feng, Weimin, additional, Xu, Yan, additional, Li, Fang, additional, Liu, Zhongmin, additional, Chen, Lei, additional, Chen, Fang, additional, Jin, Xin, additional, Qiu, Wei, additional, Yang, Huanming, additional, Wang, Jian, additional, Hua, Yan, additional, Liu, Yahong, additional, Liu, Huan, additional, and Xu, Xun, additional

Published
2020
Full Text
View/download PDF

30. Single cell chromatin accessibility of the developmental cephalochordate

Author

Chen, Dongsheng, primary, Huang, Zhen, additional, Ding, Xiangning, additional, Xu, Zaoxu, additional, Zhong, Jixing, additional, Liang, Langchao, additional, Xu, Luohao, additional, Cai, Chaochao, additional, Wang, Haoyu, additional, Qiu, Jiaying, additional, Zhu, Jiacheng, additional, Wang, Xiaoling, additional, Xiang, Rong, additional, Wu, Weiying, additional, Ding, Peiwen, additional, Wang, Feiyue, additional, Feng, Qikai, additional, Zhou, Si, additional, Yuan, Yuting, additional, Wu, Wendi, additional, Yan, Yanan, additional, Zhou, Yitao, additional, Chen, Duo, additional, Li, Guang, additional, Zhu, Shida, additional, Chen, Fang, additional, Zhang, Qiujin, additional, Wu, Jihong, additional, and Xu, Xun, additional

Published
2020
Full Text
View/download PDF

31. Single cell atlas of trisomy 21 cerebral cortex

Author

Zhang, Jingxuan, primary, Wang, Shiyou, additional, Xu, Zaoxu, additional, Ding, Xiangning, additional, Li, Chen, additional, Zhang, Yonghong, additional, Chen, Yin, additional, Zhong, Jixing, additional, Liang, Langchao, additional, Chai, Chaochao, additional, Wang, Xiaoling, additional, Xiang, Rong, additional, Zhu, Jiacheng, additional, Lin, Xiumei, additional, Ding, Peiwen, additional, Zhang, Qiang, additional, Wang, Mingyue, additional, Feng, Qikai, additional, Zhang, Zhijun, additional, Guo, Guangling, additional, Xue, Shen, additional, Jin, Lin, additional, He, Zhikai, additional, Yan, Li, additional, Xiao, Bing, additional, Zhang, Changjun, additional, Xu, Yan, additional, Li, Wei, additional, Zhang, Yichi, additional, Wu, Weiying, additional, Jiang, Sanjie, additional, Xia, Jun, additional, Gao, Ya, additional, Wang, Lei, additional, Dong, Shichen, additional, Liu, Si, additional, Zhu, Shida, additional, Chen, Fang, additional, Chen, Dongsheng, additional, and Xu, Xun, additional

Published
2020
Full Text
View/download PDF

32. Single cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina

Author

Zhong, Jixing, primary, Chen, Dongsheng, additional, Hu, Fangyuan, additional, Chen, Fang, additional, Xu, Zaoxu, additional, Fang, Jian, additional, Xu, Jianjiang, additional, Wang, Shiyou, additional, Liang, Langchao, additional, Chai, Chaochao, additional, Ding, Xiangning, additional, Zhu, Jiacheng, additional, Ding, Peiwen, additional, Xia, Jun, additional, Jiang, Sanjie, additional, Li, Wei, additional, Gao, Ya, additional, Zhang, Jianguo, additional, Li, Jiankang, additional, Xu, Ping, additional, Gao, Fengjuan, additional, Wang, Dandan, additional, Zhang, Daowei, additional, Huang, Jie, additional, Qu, Shoufang, additional, Zhang, Shenghai, additional, Wu, Jihong, additional, and Sun, Xinghuai, additional

Published
2019
Full Text
View/download PDF

33. Single cell atlas for 11 non-model mammals, reptiles and birds

Author

Dongsheng Chen, Jian Sun, Jiacheng Zhu, Xiangning Ding, Tianming Lan, Xiran Wang, Weiying Wu, Zhihua Ou, Linnan Zhu, Peiwen Ding, Haoyu Wang, Lihua Luo, Rong Xiang, Xiaoling Wang, Jiaying Qiu, Shiyou Wang, Haimeng Li, Chaochao Chai, Langchao Liang, Fuyu An, Le Zhang, Lei Han, Yixin Zhu, Feiyue Wang, Yuting Yuan, Wendi Wu, Chengcheng Sun, Haorong Lu, Jihong Wu, Xinghuai Sun, Shenghai Zhang, Sunil Kumar Sahu, Ping Liu, Jun Xia, Lijing Zhang, Haixia Chen, Dongming Fang, Yuying Zeng, Yiquan Wu, Zehua Cui, Qian He, Sanjie Jiang, Xiaoyan Ma, Weimin Feng, Yan Xu, Fang Li, Zhongmin Liu, Lei Chen, Fang Chen, Xin Jin, Wei Qiu, Tianjiao Wang, Yang Li, Xiumei Xing, Huanming Yang, Yanchun Xu, Yan Hua, Yahong Liu, Huan Liu, Xun Xu, Ding, Peiwen [0000-0003-2905-0565], Wang, Shiyou [0000-0003-1901-3920], Sahu, Sunil Kumar [0000-0002-4742-9870], Jin, Xin [0000-0001-7554-4975], Liu, Huan [0000-0003-3909-0931], Xu, Xun [0000-0002-5338-5173], and Apollo - University of Cambridge Repository

Subjects
Science, General Physics and Astronomy, Cell Communication, Article, General Biochemistry, Genetics and Molecular Biology, Birds, Evolution, Molecular, Atlases as Topic, Animal physiology, parasitic diseases, Animals, Gene Regulatory Networks, Transcriptomics, Lung, Mammals, Multidisciplinary, SARS-CoV-2, fungi, Serine Endopeptidases, Reptiles, General Chemistry, Virus Internalization, body regions, Viral Tropism, Host-Pathogen Interactions, Molecular evolution, Receptors, Virus, Evolutionary developmental biology, sense organs, Angiotensin-Converting Enzyme 2, Single-Cell Analysis, Transcriptome, Cell signalling
Abstract

The availability of viral entry factors is a prerequisite for the cross-species transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell screening of animal cells could reveal the expression patterns of viral entry genes in different hosts. However, such exploration for SARS-CoV-2 remains limited. Here, we perform single-nucleus RNA sequencing for 11 non-model species, including pets (cat, dog, hamster, and lizard), livestock (goat and rabbit), poultry (duck and pigeon), and wildlife (pangolin, tiger, and deer), and investigated the co-expression of ACE2 and TMPRSS2. Furthermore, cross-species analysis of the lung cell atlas of the studied mammals, reptiles, and birds reveals core developmental programs, critical connectomes, and conserved regulatory circuits among these evolutionarily distant species. Overall, our work provides a compendium of gene expression profiles for non-model animals, which could be employed to identify potential SARS-CoV-2 target cells and putative zoonotic reservoirs., Here the authors report single-nucleus RNA sequencing for several anatomical locations in 11 species, including cat, dog, hamster, lizard, goat, rabbit, duck, pigeon, pangolin, tiger, and deer, highlighting coexpression of SARS-CoV-2 entry factors ACE2 and TMPRSS2.

Published
2021

34. Clinicopathological and prognostic value of epithelial cell adhesion molecule in solid tumours: a meta-analysis.

Author

Ding P, Chen P, Ouyang J, Li Q, and Li S

Abstract

Background: Malignant tumors, mainly solid tumors, are a significant obstacle to the improvement of life expectancy at present. Epithelial cell adhesion molecule (EpCAM), a cancer stem cell biomarker, showed widespread expression in most normal epithelial cells and most cancers. Although the clinical significance of EpCAM in various malignant solid tumors has been studied extensively, the latent relationships between EpCAM and pathological and clinical characteristics in solid tumors and differences in the roles of EpCAM among tumors have not been clearly determined. The destination point of this study was to analyze the value of EpCAM in solid tumors in clinicopathological and prognostic dimension using a meta-analysis approach., Method and Materials: A comprehensive and systematic search of the researches published up to March 7th, 2022, in PubMed, EMBASE, Web of Science, Cochrane library and PMC databases was performed. The relationships between EpCAM overexpression, clinicopathological characteristics, and survival outcomes were analyzed. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) and odds ratios (ORs) were estimated as indicators of the degree of correlation. This research was registered on PROSPERO (International prospective register of systematic reviews), ID: CRD42022315070., Results: In total, 57 articles and 14184 cases were included in this study. High EpCAM expression had a significant coherence with a poorer overall survival (OS) (HR: 1.30, 95% CI: 1.08-1.58, P < 0.01) and a worse disease-free survival (DFS) (HR: 1.58, 95% CI: 1.28-1.95, P < 0.01), especially of gastrointestinal tumors' OS (HR: 1.50, 95% CI: 1.15-1.95, P < 0.01), and DFS (HR: 1.84, 95% CI: 1.52-2.33, P < 0.01). The DFS of head and neck tumors (HR: 2.33, 95% CI: 1.51-3.61, P < 0.01) was also associated with the overexpression of EpCAM. There were no positive relationships between the overexpression of EpCAM and sex (RR: 1.03, 95% CI: 0.99-1.07, P = 0.141), T classification (RR: 0.93, 95% CI: 0.82-1.06, P = 0.293), lymph node metastasis (RR: 0.85, 95% CI: 0.54-1.32, P = 0.461), distant metastasis (RR: 0.97, 95% CI: 0.84-1.10, P = 0.606), vascular infiltration (RR: 1.05, 95% CI: 0.85-1.29, P = 0.611), and TNM stage (RR: 0.93, 95% CI: 0.83-1.04, P = 0.187). However, the overexpression of EpCAM exhibited a significant association with the histological grades (RR: 0.88, 95% CI: 0.80-0.97, P < 0.01)., Conclusion: Based on pooled HRs, the positive expression of EpCAM was totally correlated to a worse OS and DFS in solid tumors. The expression of EpCAM was related to a worse OS in gastrointestinal tumors and a worse DFS in gastrointestinal tumors and head and neck tumors. Moreover, EpCAM expression was correlated with the histological grade. The results presented pointed out that EpCAM could serve as a prognostic biomarker for gastrointestinal and head and neck tumors., Systematic Review Registration: https://www.crd.york.ac.uk/prospero, identifier CRD42022315070., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Ding, Chen, Ouyang, Li and Li.)

Published
2023
Full Text
View/download PDF

35. Head-to-head comparison of 68 Ga-FAPI-04 PET/CT and 18 F-FDG PET/CT in the evaluation of primary digestive system cancer: a systematic review and meta-analysis.

Author

Ouyang J, Ding P, Zhang R, and Lu Y

Abstract

Introduction: Althoug 18 F-FDG positron emission tomography/computed tomography (PET/CT) is widely accepted as a diagnostic tool for detecting digestive cancers, 68 Ga-FAPI-04 PET/CT may perform better in detecting gastrointestinal malignancies at an earlier stage. This study aimed to systematically review the diagnostic performance of 68 Ga-FAPI-04 PET/CT compared with that of 18 F-FDG PET/CT in primary digestive system cancers., Methods: In this study, a comprehensive search using the PubMed, EMBASE, and Web of Science databases was performed to identify studies that met the eligibility criteria from the beginning of the databases to March 2023. The quality of the relevant studies with the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) method was assessed using the RevMan 5.3 software. Sensitivity and specificity were calculated using bivariate random-effects models, and heterogeneity was assessed with the I 2 statistic and meta-regression analysis using the R 4.22 software., Results: A total of 800 publications were identified in the initial search. Finally, 15 studies comprising 383 patients were included in the analysis. The pooled sensitivity and specificity of 68 Ga-FAPI-04 PET/CT were 0.98 (95% CI, 0.94-1.00) and 0.81 (95% CI, 0.23-1.00), whereas those of 18 F-FDG PET/CT were 0.73 (95% CI, 0.60-0.84) and 0.77 (95% CI, 0.52-0.95), respectively. 68 Ga-FAPI-04 PET/CT performed better for specific tumours, particularly in gastric, liver, biliary tract, and pancreatic cancers. Both imaging modalities had essentially the same diagnostic efficacy in colorectal cancer., Conclusions: 68 Ga-FAPI-04 PET/CT showed a higher diagnostic ability than 18 F-FDG PET/CT in terms of diagnosing primary digestive tract cancers, especially gastric, liver, biliary tract, and pancreatic cancers. The certainty of the evidence was high due to the moderately low risk of bias and low concern regarding applicability. However, the sample size of the included studies was small and heterogeneous. More high-quality prospective studies are needed to obtain higher-quality evidence in the future., Systematic Review Registration: The systematic review was registered in PROSPERO [CRD42023402892]., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Ouyang, Ding, Zhang and Lu.)

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results