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174 results on '"Ding, Y.H."'

7. A Review of Equation-of-State Models for Inertial Confinement Fusion Materials

Author

Gaffney, J.A., Hu, S.X., Arnault, P., Becker, A., Benedict, L.X., Boehly, T.R., Celliers, P.M., Ceperley, D.M., Čertík, O., Clérouin, J., Collins, G.W., Collins, L.A., Danel, J.-F., Desbiens, N., Dharma-wardana, M.W.C., Ding, Y.H., Fernandez-Pañella, A., Gregor, M.C., Grabowski, P.E., Hamel, S., Hansen, S.B., Harbour, L., He, X.T., Johnson, D.D., Kang, W., Karasiev, V.V., Kazandjian, L., Knudson, M.D., Ogitsu, T., Pierleoni, C., Piron, R., Redmer, R., Robert, G., Saumon, D., Shamp, A., Sjostrom, T., Smirnov, A.V., Starrett, C.E., Sterne, P.A., Wardlow, A., Whitley, H.D., Wilson, B., Zhang, P., and Zurek, E.

Published
2018
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17. Enhanced particle transport events approaching the density limit of the J-TEXT tokamak

Author

Long, T., primary, Diamond, P.H., additional, Ke, R., additional, Nie, L., additional, Xu, M., additional, Zhang, X.Y., additional, Li, B.L., additional, Chen, Z.P., additional, Xu, X., additional, Wang, Z.H., additional, Wu, T., additional, Tian, W.J., additional, Yuan, J.B., additional, Yuan, B.D., additional, Gong, S.B., additional, Xiao, C.Y., additional, Gao, J.M., additional, Hao, Z.G., additional, Wang, N.C., additional, Chen, Z.Y., additional, Yang, Z.J., additional, Gao, L., additional, Ding, Y.H., additional, Pan, Y., additional, Chen, W., additional, Hao, G.Z., additional, Li, J.Q., additional, Zhong, W.L., additional, and Duan, X.R., additional

Published
2021
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18. Comparison of disruption mitigation from shattered pellet injection with massive gas injection on J-TEXT

Author

Li, Y., primary, Chen, Z.Y., additional, Yan, W., additional, Wei, Y.N., additional, Tong, R.H., additional, Lin, Z.F., additional, Li, W., additional, Bai, W., additional, Wang, N.C., additional, Li, D., additional, Chen, Z.P., additional, Jiang, Z.H., additional, Yang, Z.J., additional, Ding, Y.H., additional, Pan, Y., additional, and J-TEXT Team, the, additional

Published
2021
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20. Enhancements of residual Reynolds stresses by magnetic perturbations in the edge plasmas of the J-TEXT tokamak

Author

Zhao, K.J., primary, Chen, Z.P., additional, Shi, Yuejiang, additional, Diamond, P.H., additional, Dong, J.Q., additional, Chen, Z.Y., additional, Ding, Y.H., additional, Zhuang, G., additional, Liu, Y.B., additional, Zhang, H.Q., additional, Chen, Y.Q., additional, Liu, H., additional, Cheng, J., additional, Nie, L., additional, Rao, B., additional, Cheng, Z.F., additional, Gao, L., additional, Zhang, X.Q., additional, Yang, Z.J., additional, Wang, N.C., additional, Wang, L., additional, Li, J.Q., additional, Jin, W., additional, Xu, J.Q., additional, Yan, L.W., additional, Liang, Y.F., additional, Xie, Y.Y., additional, and Liu, B., additional

Published
2020
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26. Overview of the recent experimental research on the J-TEXT tokamak

Author

Liang, Y., primary, Wang, N.C., additional, Ding, Y.H., additional, Chen, Z.Y., additional, Chen, Z.P., additional, Yang, Z.J., additional, Hu, Q.M., additional, Cheng, Z.F., additional, Wang, L., additional, Jiang, Z.H., additional, Rao, B., additional, Huang, Z., additional, Li, Y., additional, Yan, W., additional, Li, D., additional, Liu, H., additional, Zeng, L., additional, Huang, Y., additional, Huang, D.W., additional, Lin, Z.F., additional, Zheng, W., additional, Hu, F.R., additional, Zhao, K.J., additional, Jiang, M., additional, Shi, Y.J., additional, Zhou, H., additional, Peng, S.T., additional, Guo, W.X., additional, Gao, L., additional, Wang, Z.J., additional, Zhang, M., additional, Yu, K.X., additional, Hu, X.W., additional, Yu, Q., additional, Zhuang, G., additional, Gentle, K.W., additional, and Pan, Y., additional

Published
2019
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28. Influence of resonant magnetic perturbations and induced islands on plasma rotations and turbulence properties in the J-TEXT tokamak

Author

Jiang, M., primary, Xu, Y., additional, Zhong, W.L., additional, Li, D., additional, Huang, Z., additional, Yang, Z.J., additional, Shi, Z.B., additional, Wang, N.C., additional, Cheng, Z.F., additional, Yang, Z.C., additional, Liang, A.S., additional, Shi, P.W., additional, Wen, J., additional, Chen, Z.Y., additional, Chen, Z.P., additional, Pan, X.M., additional, Shi, P., additional, Ruan, B.W., additional, Guo, D.J., additional, Cai, Q.X., additional, Hu, Q.M., additional, Wang, S., additional, Ding, Y.H., additional, Ji, X.Q., additional, Li, Y.C., additional, Liu, Y., additional, and Xu, M., additional

Published
2019
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29. Bioequivalence of Sarpogrelate in Healthy Chinese Subjects Under Fasting and Fed Conditions: A 4-Way Replicate Crossover Investigation by a Reference-Scaled Average Bioequivalence Approach

Author

Ding, Y.H., primary, Liu, B., additional, Lou, J.F., additional, Sun, J.X., additional, Wu, M., additional, Zhu, X.X., additional, Chen, G.L., additional, Zhang, H., additional, Li, X.J., additional, Chen, H., additional, Liu, C.J., additional, Shen, Z.W., additional, and Li, C.Y., additional

Published
2018
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30. Minor disruptions triggered by supersonic molecular beam injection on J-TEXT tokamak.

Author

Jiang, Z.H., Yang, T.T., Yuan, J.J., Li, C.H., Ye, X., Huang, J., Liang, Y., Izzo, V.A., Huang, M.X., Tong, R.H., Huang, Y., Cai, Q.X., Yan, X.T., Zhu, L.Z., Yang, Z.J., Ding, Y.H., Zhu, P., Chen, Z.Y., and J-TEXT

Subjects
MOLECULAR beams, FUSION reactors, MAGNETOHYDRODYNAMIC instabilities, FUSION reactor divertors, PLASMA temperature, FRONTS (Meteorology), HEAT flux, MOLECULAR evolution
Abstract

Disruption mitigation experiments with supersonic molecular beam injection of argon gas on J-TEXT were conducted to explore the evolution process during multistage minor disruption. The corresponding numerical simulation was performed using a 3D magnetohydrodynamic (MHD) code, namely, NIMROD (Sovinec et al 2004 J. Comput. Phys. 195 355). The experimental and numerical simulation results are shown in the following. The central plasma temperature decreases to less than tens of electovolts after a relatively long period of multistage thermal collapse. Different MHD instability modes appear when the impurity cold front propagates toward the q = 2 surface. During the burst of MHD activity and central plasma thermal collapse, the heat flux is transferred from the core region to the plasma boundary. Further numerical simulation results show that the MHD process is accompanied by a significant increase in the core-oriented spread of impurities through the q = 2 surface. During the transition stage from the minor disruption to the major disruption, the high order modes play an important role and the magnitude of the n = 3 growth rate is even larger than that of the n = 1 or n = 2 mode. What seems to separate major from minor disruptions is that in a minor disruption, a single MHD crash is not sufficient to cause a full radiative collapse. [ABSTRACT FROM AUTHOR]

Published
2020
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33. Bioequivalence of Sarpogrelate in Healthy Chinese Subjects Under Fasting and Fed Conditions: A 4‐Way Replicate Crossover Investigation by a Reference‐Scaled Average Bioequivalence Approach.

Author

Ding, Y.H., Liu, B., Lou, J.F., Sun, J.X., Wu, M., Zhu, X.X., Chen, G.L., Zhang, H., Li, X.J., Chen, H., Liu, C.J., Shen, Z.W., and Li, C.Y.

Subjects
*LIQUID chromatography-mass spectrometry, *BIOAVAILABILITY, *INGESTION
Abstract

Sarpogrelate is widely used to treat peripheral vascular disorders. However, it has been demonstrated to have a poor pharmacokinetic (PK) profile and marked within‐subject variability. Here, the bioequivalence of 2 formulations of sarpogrelate (100‐mg tablets) was assessed by using the reference‐scaled average bioequivalence (RSABE) method, and the PK parameters were quantified in healthy Chinese subjects under fasting (n = 38) and fed (n = 35) conditions. In this open and randomized 4‐way replicate study, a single dose of sarpogrelate was administered followed by a 3‐day washout period. The sarpogrelate concentration in blood samples was measured by liquid chromatography‐tandem mass spectrometry within 6 hours (fasting) or 10 hours (fed) of drug administration, and the PK parameters were determined by a noncompartmental model. The bioequivalence of the 2 formulations under both conditions was assessed using the ratios of ln(peak concentration [Cmax]) and ln(area under the concentration‐time curve [AUC]) within the limits based on the RSABE method. The 90% CIs for the ratios of lnCmax, lnAUC0‐t, and lnAUC0‐∞ were 0.8531–1.1100, 0.9616–1.0737, and 0.9550–1.0684, respectively, under fasting conditions and 0.8918–1.1076, 0.9818–1.0694, and 0.9818–1.0686, respectively, under fed conditions, which were within the RSABE acceptance limits. Food intake decreased the systemic exposure and the Cmax of sarpogrelate by 0.9‐fold and 0.5‐fold, respectively. [ABSTRACT FROM AUTHOR]

Published
2019
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34. Theoretical study on potential-energy surface of C2N2.

Author

Ding, Y.H. and Huang, X.R.

Subjects
*POTENTIAL energy surfaces, *NUCLEAR isomers
Abstract

Examines the potential energy surface of C2N2 isomers. Use of 6-311G(d) as the basis of the calculations; Geometries of isomers obtained at B3LYP level; Transition states of C2N2 isomers.

Published
1998
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36. The behavior of runaway current in massive gas injection fast shutdown plasmas in J-TEXT

Author

Chen, Z.Y., primary, Huang, D.W., additional, Luo, Y.H., additional, Tang, Y., additional, Dong, Y.B., additional, Zeng, L., additional, Tong, R.H., additional, Wang, S.Y., additional, Wei, Y.N., additional, Wang, X.H., additional, Jian, X., additional, Li, J.C., additional, Zhang, X.Q., additional, Rao, B., additional, Yan, W., additional, Ma, T.K., additional, Hu, Q.M., additional, Yang, Z.J., additional, Gao, L., additional, Ding, Y.H., additional, Wang, Z.J., additional, Zhang, M., additional, Zhuang, G., additional, Pan, Y., additional, and Jiang, Z.H., additional

Published
2016
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47. Endovascular Treatment of Aneurysms: Healing Mechanisms in a Swine Model Are Associated with Increased Expression of Matrix Metalloproteinases, Vascular Cell Adhesion Molecule-1, and Vascular Endothelial Growth Factor, and Decreased Expression of Tissue Inhibitors of Matrix Metalloproteinases

Author

Kadirvel, R., Dai, D., Ding, Y.H., Danielson, M.A., Lewis, D.A., Cloft, H.J., and Kallmes, D.F.

Subjects
Carotid Artery Diseases, Vascular Endothelial Growth Factor A, Tissue Inhibitor of Metalloproteinase-2, Wound Healing, Tissue Inhibitor of Metalloproteinase-1, Interventional, Sus scrofa, Vascular Cell Adhesion Molecule-1, Aneurysm, Embolization, Therapeutic, Carotid Arteries, Matrix Metalloproteinase 9, cardiovascular system, Animals, Matrix Metalloproteinase 2, Female, cardiovascular diseases
Abstract

BACKGROUND AND PURPOSE: The mechanism of aneurysm healing after coiling remains poorly understood. The purpose of the study was to obtain a better understanding of the cellular and molecular events that are associated with aneurysm healing after endovascular coiling in a swine aneurysm model. MATERIALS AND METHODS: Twenty sidewall aneurysms were created surgically in common carotid arteries in 10 swine. These aneurysms were embolized immediately after creation by using platinum coils by endovascular means. Two and 12 weeks after implantation, aneurysm samples were collected for histologic and biochemical analysis. RESULTS: All aneurysms were completely or nearly completely occluded angiographically at the time of embolization and at follow-up. At 2 weeks, aneurysm cavities were filled with inflammatory cells and myofibroblasts. At 12 weeks, aneurysm cavities were filled with richly vascularized fibrous tissue and disorganized collagen bundles. The expression of matrix metalloproteinase (MMP)-2 and -9 was found to be elevated at 2 weeks. Expression remained greater than that in control tissue at 12 weeks but was significantly decreased compared with the earlier time point. Expression of tissue inhibitors of MMPs (TIMPs) was diminished at both time points. Expression of vascular cell adhesion molecule-1 (VCAM-1) and vascular endothelial growth factor (VEGF) was elevated at both 2 weeks and 12 weeks. Endothelial nitric oxide synthase expression was not different from that in controls. Transforming growth factor-beta expression was elevated at 2 weeks only. CONCLUSION: The coil occlusion in this model that is prone to heal is associated with increased expression of MMP-2, MMP-9, VCAM-1, and VEGF, and decreased expression of TIMPs.

Published
2007

48. mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays

Author

Mangrum, W.I., Farassati, F., Kadirvel, R., Kolbert, C.P., Raghavakaimal, S., Dai, D., Ding, Y.H., Grill, D., Khurana, V.G., and Kallmes, D.F.

Subjects
Disease Models, Animal, Interventional, Pancreatic Elastase, Carotid Artery, Common, Reverse Transcriptase Polymerase Chain Reaction, cardiovascular system, Animals, Intracranial Aneurysm, cardiovascular diseases, RNA, Messenger, Rabbits, Oligonucleotide Array Sequence Analysis
Abstract

BACKGROUND AND PURPOSE: The molecular characteristics of intracranial aneurysms are still poorly documented. A rabbit elastase aneurysm model has been helpful in the evaluation of devices and strategies involved in endovascular treatment of aneurysms. The goal of this project was to document the molecular changes, assessed by gene chip microarrays, associated with the creation of aneurysms in this model compared with the contralateral carotid artery. MATERIALS AND METHODS: A microarray of rabbit genes of interest was constructed using rabbit nucleotide sequences from GenBank. Elastase-induced saccular aneurysms were created at the origin of the right common carotid artery in 4 rabbits. Twelve weeks after aneurysm creation, RNA was isolated from the aneurysm as well as the contralateral common carotid artery and used for microarray experiments. Reverse transcription-polymerase chain reaction (RT-PCR) was performed on 1 animal as a confirmatory test. RESULTS: Ninety-six (46%) of 209 genes in the microarray were differentially expressed in the rabbit aneurysm compared with the contralateral common carotid artery. In general, differential gene expression followed specific molecular pathways. Similarities were found between rabbit aneurysms and human intracranial aneurysms, including increased metalloproteinase activity and decreased production of the extracellular matrix. RT-PCR results confirmed the differential expression found by the gene chip microarray. CONCLUSIONS: The molecular characteristics of the rabbit elastase-induced saccular aneurysm are described. The rabbit aneurysm model shares some molecular features with human intracranial aneurysms. Future studies can use the rabbit model and the new rabbit gene chip microarray to study the molecular aspects of saccular aneurysms.

Published
2007

49. Control of Aneurysm Volume by Adjusting the Position of Ligation During Creation of Elastase-Induced Aneurysms: A Prospective Study

Author

Ding, Y.H., Dai, D., Danielson, M.A., Kadirvel, R., Lewis, D.A., Cloft, H.J., and Kallmes, D.F.

Subjects
Disease Models, Animal, Interventional, Pancreatic Elastase, Angiography, Digital Subtraction, Animals, Intracranial Aneurysm, Rabbits, Ligation, Cerebral Angiography
Abstract

BACKGROUND AND PURPOSE: Animal models with appropriate volume are crucial for preclinical assessment of aneurysm therapies. Our purpose was to control the aneurysm volume by adjusting the position of ligation during creation of elastase-induced aneurysms in rabbits. MATERIALS AND METHODS: Sixty elastase-induced aneurysms in rabbits were created. Two different methods were used for creation, including group 1 (n = 30) by using a lower ligation (from the origin of the right common carotid artery [RCCA] to the ligation point, 10 mm) and group 2 (n = 30) by using a higher ligation (from the origin of the RCCA to the ligation point, 15 mm). Aneurysm sizes (neck diameter, width, and height) and volumes in the 2 groups were measured and calculated, and they were compared by using the Student t test. RESULTS: The mean aneurysm neck diameter, width, and height for group 2 were significantly larger than those of group 1 (3.3 ± 0.8 versus 2.7 ± 0.6 mm, P < .001; 3.7 ± 0.7 versus 2.5 ± 0.7 mm, P < .001; 9.0 ± 1.7 versus 7.3 ± 1.9 mm, P < .001, respectively). The aneurysm volume in group 2 was significantly larger than that in group 1 (102.4 ± 54.8 mm(3) versus 36.6 ± 26.8 mm(3), P < .001). CONCLUSION: The aneurysm volume of elastase-induced models in rabbits can be controlled by adjusting the position of the ligation. Using a higher ligation can create relatively more voluminous aneurysms, compared with using a lower ligation.

Published
2007

50. Introduction to resonant magnetic perturbation coils of the J-TEXT Tokamak

Author

Rao, B., primary, Wang, G., additional, Ding, Y.H., additional, Yu, K.X., additional, Li, Q.L., additional, Wang, N.C., additional, Yi, B., additional, Nan, J.Y., additional, Cen, Y.S., additional, Hu, Q.M., additional, Jin, W., additional, Li, J.C., additional, Jin, H., additional, Zhang, M., additional, and Zhuang, G., additional

Published
2014
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