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167 results on '"Ditah, Ivo"'

11. Liver Transplantation Trends and Outcomes for Hereditary Hemorrhagic Telangiectasia in the United States

Author

Iyer, Vivek N., primary, Saberi, Behnam, additional, Heimbach, Julie K., additional, Larson, Joseph J., additional, Raghavaiah, Suresh, additional, Ditah, Ivo, additional, Swanson, Karen, additional, Kamath, Patrick S., additional, Watt, KD, additional, Taner, Timucin, additional, Krowka, Michael J., additional, and Leise, Michael D., additional

Published
2019
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13. Use of Transient Elastography in Patients with HIV-HCV Co-infection: A Systematic Review and Meta-analysis

Author

Njei, Basile, McCarty, Thomas R., Luk, Jeffrey, Ewelukwa, Oforbuike, Ditah, Ivo, and Lim, Joseph K.

Subjects
Liver Cirrhosis, Coinfection, Elasticity Imaging Techniques, Humans, HIV Infections, Hepatitis C, Sensitivity and Specificity, Article
Abstract

Patients with HIV-hepatitis C virus (HCV) coinfection progress towards liver fibrosis and cirrhosis more rapidly compared with HCV mono-infected individuals. This necessitates an accurate assessment of liver stiffness with transient elastography to guide treatment.Searches of PubMed, EMBASE, Web of Science, and the Cochrane Library databases were performed through January 2016 to assess the diagnostic accuracy of transient elastography for liver stiffness in the HIV-HCV population. Included studies were analyzed according to the Cochrane DTA Working Group methodology. Bivariate and hierarchical models were used to compute pooled sensitivity and specificity. Positive and negative likelihood ratios were also determined. A Fagan nomogram was constructed. Meta-regression analysis was performed with assessment of publication bias using Deeks' funnel plot asymmetry testing.A total of six studies (n = 756) met the inclusion criteria. The diagnostic accuracy of elastography for the diagnosis of moderate (≥F2) fibrosis was 88% (95% confidence interval [CI], 0.85-0.90). The pooled sensitivity and specificity of moderate fibrosis was 97% (95% CI, 0.82-0.91) and 64% (95% CI, 0.45-0.79), respectively. The diagnostic accuracy of elastography for the assessment of cirrhosis was 94% (95% CI, 0.91-0.95). The pooled sensitivity and specificity for cirrhosis was 90% (95% CI, 0.74-0.97) and 87% (95% CI, 0.80-0.92), respectively. Meta-regression analysis demonstrated that CD4 cell count did not impact diagnostic accuracy of elastography.Transient elastography is a noninvasive imaging modality with excellent ability to assess for cirrhosis in patients with HIV-HCV coinfection.

Published
2016

26. Trends and Racial/Ethnic Disparities in Gluten-Sensitive Problems in the United States: Findings from the National Health and Nutrition Examination Surveys From 1988 to 2012

Author

Choung, Rok Seon, primary, Ditah, Ivo C, additional, Nadeau, Ashley M, additional, Rubio-Tapia, Alberto, additional, Marietta, Eric V, additional, Brantner, Tricia L, additional, Camilleri, Michael J, additional, Rajkumar, Vincent S, additional, Landgren, Ola, additional, Everhart, James E, additional, and Murray, Joseph A, additional

Published
2015
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31. Anorectal pathology amongst HIV infected patients attending the Douala General Hospital: a cross-sectional study.

Author

Luma, Henry Namme, Eloumou, Servais Albert Fiacre Bagnaka, Fualefeh-Morfaw, Ellis Atemlefeh, Malongue, Agnes, Temfack, Elvis, Lekpa, Fernando Kemta, Donfack-Sontsa, Olivier, Ndip, Lucy, and Ditah, Ivo Che

Subjects
GASTROINTESTINAL diseases, ANORECTAL function tests, HEMORRHOIDS, PROCTITIS, HIV-positive persons, HIV infection epidemiology, HIV infections, HOSPITALS, QUALITY of life, RECTAL diseases, LOGISTIC regression analysis, HIGHLY active antiretroviral therapy, DISEASE prevalence, CROSS-sectional method, SEXUAL partners, CD4 lymphocyte count
Abstract

While gastrointestinal disease is common among HIV infected individuals, the prevalence and distribution of ano-rectal pathology has not been well studied in our setting. The objective of this study therefore was to determine the prevalence and determinants of ano-rectal pathology in HIV infected patients attending the Douala General Hospital HIV treatment centre. A hospital-based cross-sectional study was undertaken. We collected socio-demographic, clinical and laboratory data using a structured questionnaire and patients' files. Each study participant had a full physical and ano-rectal examination. We further studied factors associated with having at least one ano-rectal lesion by logistic regression reporting odds ratios (ORs) and their 95% confidence intervals (CI). We included 390 HIV infected patients. The mean age was 41 (SD: 8) years and 48% were men. Median duration since HIV diagnosis was 3 (interquartile range: 2-5) years and median CD4 cell count was 411 (interquartile range: 234-601) cells/mm3. Prevalence of ano-rectal pathology was 22.8% (95% CI: 18.7-27.3). Hemorrhoids and proctitis were most common lesions found; each in 10% of patients. From multivariate logistic regression, factors associated with ano-rectal pathology were CD4 < 350 cells/ml (OR: 2.1, 95% CI: 1.1-4.2), not on highly active antiretroviral therapy (OR: 2.2, 95% CI: 1.1-4.6), inpatient (OR: 2.3, 95% CI: 1.2-4.3), ano-rectal intercourse (OR: 5.0, 95% CI: 1.7-15.1), and more than one sexual partner (OR: 2.4, 95% CI: 1.3-4.2). Ano-rectal pathology is common amongst HIV infected patients. Care givers should actively investigate and treat them as this will improve the quality of life of people living with HIV/AIDS. [ABSTRACT FROM AUTHOR]

Published
2017
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